pamidronate has been researched along with Paget Disease, Extramammary in 2 studies
Paget Disease, Extramammary: A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intravenous drip of pamidronate was given at the dose of 30 - 60 mg per day for 2 - 3 weeks with a total dosage of 90 - 270 (168 +/- 84) mg to 5 patients with Paget's disease of bone, 2 males and 3 females, aged 27 - 74 (61 on average) with the course of disease of 4 - 48 years (24 years on average), all of them having multiple bone lesions, 2 being in grade 4 of pain assessment and bedridden and 3 being in grade 3 with impaired mobility." | 1.32 | [Prospective study of pamidronate disodium in treatment of Paget's disease of bone]. ( Fu, Y; Jiang, Y; Li, M; Meng, XW; Wang, O; Xia, WB; Xing, XP; Zhang, ZL; Zhou, XY, 2003) |
| " There was no dose-response relationship between the dose of APD given and the percentage reduction in ALP and HYPRO at 6 months." | 1.28 | Bisphosphonate space measurement in Paget's disease of bone treated with APD. ( Evans, AJ; Hosking, DJ; Marshall, DH; Perkins, AC; Stone, MD; Wastie, ML, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, ZL | 1 |
| Meng, XW | 1 |
| Xing, XP | 1 |
| Wang, O | 1 |
| Xia, WB | 1 |
| Li, M | 1 |
| Jiang, Y | 1 |
| Fu, Y | 1 |
| Zhou, XY | 1 |
| Stone, MD | 1 |
| Marshall, DH | 1 |
| Hosking, DJ | 1 |
| Perkins, AC | 1 |
| Evans, AJ | 1 |
| Wastie, ML | 1 |
2 other studies available for pamidronate and Paget Disease, Extramammary
| Article | Year |
|---|---|
[Prospective study of pamidronate disodium in treatment of Paget's disease of bone].
Topics: Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Diphosphonates; Female; Humans; Male; Middle Age | 2003 |
Bisphosphonate space measurement in Paget's disease of bone treated with APD.
Topics: Alkaline Phosphatase; Bone and Bones; Creatinine; Diphosphonates; Humans; Hydroxyproline; Infusions, | 1992 |