Page last updated: 2024-11-02

pamidronate and Milk-Alkali Syndrome

pamidronate has been researched along with Milk-Alkali Syndrome in 311 studies

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the efficacy and safety of pamidronate in HD patients affected by severe secondary hyperparathyroidism and moderate hypercalcemia who were receiving intravenous calcitriol (Calcijex)."9.10Usefulness of pamidronate in severe secondary hyperparathyroidism in patients undergoing hemodialysis. ( Fuster, D; Mas, M; Moreno, A; Torregrosa, JV; Ybarra, J, 2003)
"To compare the efficacy and safety of ibandronate and pamidronate in patients with hypercalcemia of malignancy (HCM)."9.10Efficacy and safety of ibandronate in the treatment of hypercalcemia of malignancy: a randomized multicentric comparison to pamidronate. ( Bergström, B; Pecherstorfer, M; Rizzoli, R; Steinhauer, EU; Wetterwald, M, 2003)
"To assess whether pamidronate can reduce the frequency of skeletal morbidity in women with lytic bone metastases from breast cancer treated with hormone therapy."9.09Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: a randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group. ( Costello, S; Glück, S; Heffernan, M; Hortobagyi, GN; Kennedy, I; Knight, RD; Leff, R; Lipton, A; Mellars, K; Reitsma, DJ; Seaman, JJ; Simeone, J; Stewart, JF; Theriault, RL, 1999)
"Patients with stage III multiple myeloma and at least one lytic lesion received either placebo or pamidronate (90 mg) as a four-hour intravenous infusion given every four weeks for nine cycles in addition to antimyeloma therapy."9.08Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group. ( Ballester, O; Bell, R; Berenson, JR; Blacklock, HA; Bordoni, R; Dimopoulos, MA; George, S; Heffernan, M; Keller, A; Knight, RD; Kovacs, MJ; Lichtenstein, A; Lipton, A; Porter, L; Reitsma, DJ; Seaman, J; Simeone, J, 1996)
"A group of 38 female patients with advanced breast cancer experiencing the first occurrence of tumour-induced hypercalcaemia (TIH), mostly with osteolytic progressive bone metastases, were included in a prospective calcaemia-adapted study using three different doses of pamidronate (30 mg, 45 mg and 60 mg)."9.08Treatment of tumour-induced hypercalcaemia in advanced breast cancer patients with three different doses of disodium pamidronate adapted to the initial level of calcaemia. ( Mitrović, L; Nesković-Konstantinović, Z; Petrović, J; Ristović, Z; Stamatović, L, 1995)
"Women with stage IV breast cancer who were receiving cytotoxic chemotherapy and had at least one lytic bone lesion were given either placebo or pamidronate (90 mg) as a two-hour intravenous infusion monthly for 12 cycles."9.08Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group. ( Blayney, D; Hortobagyi, GN; Knight, RD; Lipton, A; Porter, L; Seaman, J; Simeone, JF; Sinoff, C; Theriault, RL; Wheeler, H, 1996)
"The superiority of pamidronate in controlling hypercalcemia is mirrored by the changes observed in these markers."9.08Evaluation of new bone resorption markers in a randomized comparison of pamidronate or clodronate for hypercalcemia of malignancy. ( Coleman, RE; Eastell, R; Guo, CY; Purohit, OP; Vinholes, J, 1997)
"We assessed the effects of 60-mg single doses of pamidronate disodium compared with saline alone in the treatment of cancer-associated hypercalcemia."9.07Treatment of cancer-associated hypercalcemia. Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone. ( Ahmann, F; Chapman, R; Gill, I; Gucalp, R; Heffernan, M; Knight, RD; Madajewicz, S; Navari, R; Theriault, R; Zelenakas, K, 1994)
"To determine the efficacy, dose-response relationship, and safety of 30, 60, and 90 mg of a single intravenous dose of an aminobisphosphonate, pamidronate (APD), for the treatment of moderate to severe hypercalcemia of malignancy."9.07Single-dose intravenous therapy with pamidronate for the treatment of hypercalcemia of malignancy: comparison of 30-, 60-, and 90-mg dosages. ( Chapman, R; Gagel, RF; Henderson, IC; Mallette, LE; Nussbaum, SR; Vandepol, CJ; Younger, J; Zubler, MA, 1993)
"We have conducted a randomized crossover comparative trial of a single-dose course of disodium (3-amino-1-hydroxypropylidene) bisphosphonate pentahydrate (pamidronate) and plicamycin in 48 patients with a first occurrence of tumor-related hypercalcemia."9.07Plicamycin and pamidronate in symptomatic tumor-related hypercalcemia: a prospective randomized crossover trial. ( Senn, HJ; Thiébaud, D; Thürlimann, B; Waldburger, R, 1992)
"This multicenter, double-blind, randomized trial was performed to determine the efficacy and safety of pamidronate disodium (APD) in comparison to etidronate disodium (EHDP) in the treatment of cancer-related hypercalcemia."9.07Comparative study of pamidronate disodium and etidronate disodium in the treatment of cancer-related hypercalcemia. ( Gucalp, R; Keller, A; Mallette, LE; Neidhart, J; Richman, SP; Ritch, P; Sarma, PR; Siegel, R; Tauer, K; Wiernik, PH, 1992)
"The improved efficacy of zoledronic acid compared with pamidronate disodium has been demonstrated in a pooled analysis of two randomized clinical trials in patients with hypercalcemia of malignancy."8.81The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy. ( Major, P, 2002)
"Two identical, concurrent, parallel, multicenter, randomized, double-blind, double-dummy trials were conducted to compare the efficacy and safety of zoledronic acid and pamidronate for treating hypercalcemia of malignancy (HCM)."8.81Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials. ( Abdi, E; Bell, R; Body, J; Hon, J; Lortholary, A; Major, P; Menssen, HD; Mills, G; Quebe-Fehling, E; Seaman, J; Yunus, F, 2001)
"Salmon calcitonin has been used for the management of acute hypercalcemia for the past several years."8.78Salmon calcitonin in the acute management of hypercalcemia. ( Wisneski, LA, 1990)
"The primary objective was to compare the incidence of acute kidney injury (AKI) within 7 days of receiving pamidronate for the treatment of HCM with pre-existing renal dysfunction versus normal renal function at the time of pamidronate administration."8.02Use of Pamidronate for Hypercalcemia of Malignancy in Renal Dysfunction. ( Norman, SJ; Reeves, DJ; Saum, LM, 2021)
"This is a case report of a patient who developed severe, irreversible hypocalcemia after receiving one dose of pamidronate 90 mg for hypercalcemia of malignancy."7.91A case of severe, irreversible hypocalcemia after one dose of pamidronate administered for hypercalcemia of malignancy. ( Kim, S, 2019)
" Acute renal failure due to severe hypercalcemia and nephrocalcinosis treated with two doses of pamidronate in an infant with Williams-Beuren syndrome."7.88Acute renal failure due to severe hypercalcemia and nephrocalcinosis treated with two doses of pamidronate in an infant with Williams-Beuren syndrome. ( Baş, VN; Baştuğ, F; Çetinkaya, H; Nalçacıoğlu, H; Tekatlı-Çelik, B; Yel, S, 2018)
" We report a case in which a patient with tertiary hyperparathyroidism and refractory hypercalcemia who was not a surgical candidate was managed with the bisphosphonate pamidronate."7.75Hypercalcemia associated with tertiary hyperparathyroidism managed conservatively with pamidronate in a hemodialysis patient. ( Canada, RB; Czosnowski, LM; Hudson, JQ, 2009)
" When conventional treatment of hypercalcemia failed, pamidronate dramatically decreased both the calcium levels and the frequency of uterine contractions."7.73Malignant hypercalcemia in pregnancy: effect of pamidronate on uterine contractions. ( Culbert, EC; Schfirin, BS, 2006)
"To describe extreme hypercalcemia as the presenting feature of acute lymphoblastic leukemia in an 8-yr-old girl and the combined use of pamidronate and calcitonin for its treatment."7.72Treatment of acute lymphoblastic leukemia-induced extreme hypercalcemia with pamidronate and calcitonin. ( Goldman, GM; Mathur, M; Rao, SP; Saxena, VR; Sykes, JA, 2003)
"The purpose of this study is to evaluate the acute effect of pamidronate on plasma ionized calcium (iCa) level reduction and dynamic parathyroid hormone (PTH) secretion in postmenopausal hemodialysis-dependent women with secondary hyperparathyroidism."7.72Acute effect of pamidronate on PTH secretion in postmenopausal hemodialysis patients with secondary hyperparathyroidism. ( Chu, P; Lin, SH; Lin, YF; Lu, KC; Yeung, LK, 2003)
"We commend the short-term use of pamidronate in neonatal severe hyperparathyroidism to treat extreme hypercalcaemia and halt hyperparathyroid-driven skeletal demineralisation in preparation for parathyroidectomy."7.72Neonatal severe hyperparathyroidism: genotype/phenotype correlation and the use of pamidronate as rescue therapy. ( Cheetham, T; Cranston, T; Kurzawinski, T; Pearce, S; Spitz, L; Thakker, R; van't Hoff, WG; Waller, S, 2004)
"To report the efficacy of Pamidronate to treat hypercalcaemia in a patient with Williams-Beuren syndrome (WBS)."7.72Long-term control of hypercalcaemia in an infant with williams-Beuren syndrome after a single infusion of biphosphonate (Pamidronate). ( Gravano, JC; Mastaglia, SR; Mautalen, C; Oliveri, B; Pardo Argerich, L, 2004)
"To determine whether pamidronate is a safe and effective agent for the treatment of severe hypercalcemia of malignancy in children."7.70Use of pamidronate in the management of acute cancer-related hypercalcemia in children. ( Shende, A; Young, G, 1998)
"Pamidronate disodium, a bone resorption inhibitor through osteoclast mediation, has been used to treat chronic hypercalcemia secondary to malignancy and chronic renal failure."7.70The use of pamidronate for hypercalcemia secondary to acute vitamin D intoxication. ( Lee, DC; Lee, GY, 1998)
" He was treated with seven courses of combined chemotherapy (CDDP + etoposide), until he showed extreme hypercalcemia and acute renal failure."7.70[A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate]. ( Kametani, T; Koshida, H; Masuda, S, 1999)
"To review the use of pamidronate to treat immobilization hypercalcemia after acute spinal cord injury (SCI) in 9 cases."7.70Immobilization hypercalcemia treatment with pamidronate disodium after spinal cord injury. ( Cardenas, DD; Massagli, TL, 1999)
"Two patients with malignancy-associated hypercalcemia from bone metastases of breast cancer, accompanied by consciousness disturbance, were treated by a combination therapy of pamidronate and salmon calcitonin."7.70[Two cases of malignancy-associated hypercalcemia from bone metastases of breast cancer successfully treated with combination therapy using pamidronate and calcitonin]. ( Aoki, T; Kaise, H; Koyanagi, Y; Kusama, M; Matsunaga, T; Nakamura, Y; Nakayama, S; Ota, D, 2000)
"The purpose of this study was to investigate the effects of pamidronate, a second generation bisphosphonate, on the change in calcium homeostasis in patients with tumor-associated hypercalcemia."7.69Pamidronate treatment in patients with tumor-associated hypercalcemia: pharmacological effects and pharmacokinetics. ( Ariyoshi, Y; Hasegawa, H; Niinomi, M; Oiso, Y; Sakiyama, N; Takano, T; Tomita, A; Yamamoto, M, 1994)
"Intravenous pamidronate disodium has been used successfully in the treatment of malignancy-associated hypercalcemia and Paget's disease of bone."7.69Intravenous pamidronate for hypercalcemia of primary hyperparathyroidism. ( Graves, L; Tal, A, 1996)
"Pamidronate (APD) is a drug widely used for the treatment of hypercalcemia of malignancy."7.69Safety of pamidronate in patients with renal failure and hypercalcemia. ( Flombaum, CD; Machado, CE, 1996)
"A 65-year-old woman admitted for palliative care of metastatic renal/bladder carcinoma developed symptomatic hypocalcemia nine days following a single dose of pamidronate."7.69Symptomatic hypocalcemia after intravenous pamidronate. ( Bruera, E; McIntyre, E, 1996)
"Pamidronate is a second generation bisphosphonate used for treating tumor-induced hypercalcemia and for preventing the development of new bone metastasis."7.69[Effect of pamidronate and interferon-alpha on bone and lung metastases and hypercalcemia in a patient with renal cell carcinoma]. ( Arima, K; Hioki, T; Kawamura, J; Kise, H; Kobayashi, K; Sugiura, Y; Tochigi, H; Yanagawa, M, 1996)
"The response to the bisphosphonate, pamidronate, is reported in a child with osteogenesis imperfecta who had recurrent symptomatic hypercalcaemia after immobilisation following fractures."7.69Hypercalcaemia in osteogenesis imperfecta treated with pamidronate. ( Ball, RJ; Smith, RA; Wilkinson, H; Williams, CJ, 1997)
"Hypercalcemia in a 4-year-old boy with non-Hodgkin lymphoma treated with pamidronate is presented."7.69Childhood cancer and hypercalcemia: report of a case treated with pamidronate. ( Akyüz, C; Büyükpamukçu, M; Hazar, V; Kutluk, MT; Varan, A, 1997)
" The time course study on the antihypercalcemic effect of pamidronate was performed using a rat hypercalcemia model induced by orally administered cholecalciferol."7.68Effect of pamidronate in a rat hypercalcemia model induced by cholecalciferol. ( Hasegawa, Y; Inukai, T; Noguchi, S; Okada, M, 1992)
"Pamidronate (aminopropylidene diphosphonate, APD) is known to be an effective agent in lowering plasma calcium in cancer associated hypercalcaemia and in primary hyperparathyroidism."7.68[Combination therapy with pamidronate and calcitonin in hypercalcemic crisis caused by primary hyperparathyroidism]. ( Christensen, JH; Kristiansen, JH, 1992)
"The effect of lowering ionized calcium on circulating parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) was assessed in twenty patients with hypercalcemia of malignancy following treatment with Pamidronate Disodium."7.68Circulating PTH and PTHrP levels before and after treatment of tumor induced hypercalcemia with Pamidronate Disodium (APD). ( Grill, V; Ho, PW; Jerums, G; Martin, TJ; Murray, RM; Pitt, P; Potts, C; Santamaria, JD, 1992)
"Nine patients (median age, 81 years) with primary hyperparathyroidism were treated with intravenous infusions of disodium pamidronate (APD), which is a bisphosphonate drug."7.68Disodium pamidronate in the preoperative treatment of hypercalcemia in patients with primary hyperparathyroidism. ( Jansson, S; Lindstedt, G; Lundberg, PA; Tisell, LE, 1991)
"Seventeen patients with malignant hypercalcemia were treated with a combination of a single dose of 3-amino 1-hydroxypropylidene-1-bisphosphonate (APD [also known as AHPrBP or palmidronate disodium]) and salmon calcitonin given as suppositories for 3 days."7.68Fast and effective treatment of malignant hypercalcemia. Combination of suppositories of calcitonin and a single infusion of 3-amino 1-hydroxypropylidene-1-bisphosphonate. ( Burckhardt, P; Jacquet, AF; Thiébaud, D, 1990)
"Pamidronate treatment also did not have any influence on patient survival or on the frequency of hypercalcaemia."6.69Failure of oral pamidronate to reduce skeletal morbidity in multiple myeloma: a double-blind placebo-controlled trial. Danish-Swedish co-operative study group. ( Abildgaard, N; Brincker, H; Ford, J; Gimsing, P; Hedenus, M; Kandra, A; Turesson, I; Westin, J, 1998)
"Pamidronate was given in a single infusion on day 0, the dose of pamidronate adapted to the severity of hypercalcemia."6.67[Pamidronate in the treatment of tumor-associated hypercalcemia]. ( Bosse, C; Fortelny, A; Gerber, E; Janisch, S; Lenzhofer, R; Marosi, C; Pecherstorfer, M; Rainer, H; Schratzberger, W; Wogritsch, C, 1991)
" Review of the published literature suggests that a clinically relevant dose-response relationship exists in the dose range 30-60 mg; most hypercalcemic patients will achieve normocalcemia with a dose of 60 mg pamidronate or more."6.39Progress in the treatment and palliation of advanced breast cancer: does the dose of pamidronate determine its effects? ( Thürlimann, B, 1994)
"This study demonstrates that Pam is effective and safe for treating PTHRH, while ensuring close laboratory monitoring of calcium and phosphorus metabolism."5.62Efficacy and Safety of Intravenous Pamidronate for Parathyroid Hormone-dependent Hypercalcemia in Hospitalized Patients. ( Barzilay-Yoseph, L; Klein, N; Ramaty, E; Rosenblum, RC; Rotman-Pikielny, P; Twito, O, 2021)
"BACKGROUND Hypercalcemia is a common complication in the intensive care unit (ICU)."5.48Use of Pamidronate to Treat Hypercalcemia in an Oncology Dialysis Patient: A Case Report. ( El Madhoun, I; El Zeer, HS; Khatib, M; Mahmoud, S; Mitwally, H, 2018)
"Pamidronate has a beneficial effect in those patients with IIH where glucocorticoids and furosemide fail to meet the expectations."5.39Intravenous pamidronate in the treatment of severe idiopathic infantile hypercalcemia. ( Bayer, M; Cerna, L; Konrad, M; Kutilek, S; Schlingmann, KP; Skalova, S, 2013)
"Subcutaneous fat necrosis of the newborn (SCFN) is a panniculitis that develops in fatty areas during the first weeks of life after foetal distress or perinatal complications."5.35Effectiveness of pamidronate in severe neonatal hypercalcemia caused by subcutaneous fat necrosis: a case report. ( Bollani, L; Cabano, R; Del Forno, C; Lombardi, G; Stronati, M, 2009)
"Treatments of hypercalcemia have included hydration, furosemide and corticosteroids."5.33Pamidronate: Treatment for severe hypercalcemia in neonatal subcutaneous fat necrosis. ( Alos, N; Chabot, G; Eugène, D; Fillion, M; Kokta, V; Powell, J, 2006)
"The use of pamidronate for treatment of hypercalcemia and chronic conditions that affect normal bone growth is increasing in children."5.32Pamidronate treatment for hypercalcemia in an infant receiving parenteral nutrition. ( Bryowsky, JJ; Bugnitz, MC; Hak, EB, 2004)
"Although treatment of hypercalcemia with pamidronate is palliative, it is effective against the deterioration of quality of life."5.31[Treatment of hypercalcemia of malignancy with pamidronate in a patient with advanced recurrent oral cancer]. ( Hashitani, S; Matsushita, Y; Nishimura, N; Noguchi, K; Takaoka, K; Urade, M, 2002)
"Alendronate is an aminobisphosphonate that acts as a potent inhibitor of osteoclastic bone resorption."5.29Alendronate distributed on bone surfaces inhibits osteoclastic bone resorption in vitro and in experimental hypercalcemia models. ( Azuma, Y; Kiyoki, M; Ohta, T; Okabe, K; Oue, Y; Sato, H; Tsuchimoto, M, 1995)
"Parathyroid carcinoma is rare and the associated hypercalcaemia is often resistant to all treatment."5.29Prolonged remission of hypercalcaemia due to parathyroid carcinoma with pamidronate. ( Braatvedt, GD; Corrall, RJ; Newrick, PG; Sheffield, E; Webb, AJ, 1994)
"The aim of this study was to evaluate the efficacy and safety of pamidronate in HD patients affected by severe secondary hyperparathyroidism and moderate hypercalcemia who were receiving intravenous calcitriol (Calcijex)."5.10Usefulness of pamidronate in severe secondary hyperparathyroidism in patients undergoing hemodialysis. ( Fuster, D; Mas, M; Moreno, A; Torregrosa, JV; Ybarra, J, 2003)
"To compare the efficacy and safety of ibandronate and pamidronate in patients with hypercalcemia of malignancy (HCM)."5.10Efficacy and safety of ibandronate in the treatment of hypercalcemia of malignancy: a randomized multicentric comparison to pamidronate. ( Bergström, B; Pecherstorfer, M; Rizzoli, R; Steinhauer, EU; Wetterwald, M, 2003)
" infusion of pamidronate 90 mg in the treatment of malignant hypercalcemia."5.10Clodronate as a single-dose intravenous infusion effectively provides short-term correction of malignant hypercalcemia. ( Atula, ST; Nevalainen, JI; Pylkkänen, LH; Tähtelä, RK, 2003)
"To assess whether pamidronate can reduce the frequency of skeletal morbidity in women with lytic bone metastases from breast cancer treated with hormone therapy."5.09Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: a randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group. ( Costello, S; Glück, S; Heffernan, M; Hortobagyi, GN; Kennedy, I; Knight, RD; Leff, R; Lipton, A; Mellars, K; Reitsma, DJ; Seaman, JJ; Simeone, J; Stewart, JF; Theriault, RL, 1999)
"Bisphosphonates are now the standard treatment for tumor-induced hypercalcemia (TIH), and pamidronate can normalize serum Ca in at least 90% of the patients treated for the first time."5.09Decreased efficacy of bisphosphonates for recurrences of tumor-induced hypercalcemia. ( Body, JJ; Dumon, JC; Louviaux, I, 2000)
"Patients with stage III multiple myeloma and at least one lytic lesion received either placebo or pamidronate (90 mg) as a four-hour intravenous infusion given every four weeks for nine cycles in addition to antimyeloma therapy."5.08Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group. ( Ballester, O; Bell, R; Berenson, JR; Blacklock, HA; Bordoni, R; Dimopoulos, MA; George, S; Heffernan, M; Keller, A; Knight, RD; Kovacs, MJ; Lichtenstein, A; Lipton, A; Porter, L; Reitsma, DJ; Seaman, J; Simeone, J, 1996)
"A group of 38 female patients with advanced breast cancer experiencing the first occurrence of tumour-induced hypercalcaemia (TIH), mostly with osteolytic progressive bone metastases, were included in a prospective calcaemia-adapted study using three different doses of pamidronate (30 mg, 45 mg and 60 mg)."5.08Treatment of tumour-induced hypercalcaemia in advanced breast cancer patients with three different doses of disodium pamidronate adapted to the initial level of calcaemia. ( Mitrović, L; Nesković-Konstantinović, Z; Petrović, J; Ristović, Z; Stamatović, L, 1995)
"Women with stage IV breast cancer who were receiving cytotoxic chemotherapy and had at least one lytic bone lesion were given either placebo or pamidronate (90 mg) as a two-hour intravenous infusion monthly for 12 cycles."5.08Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group. ( Blayney, D; Hortobagyi, GN; Knight, RD; Lipton, A; Porter, L; Seaman, J; Simeone, JF; Sinoff, C; Theriault, RL; Wheeler, H, 1996)
"The superiority of pamidronate in controlling hypercalcemia is mirrored by the changes observed in these markers."5.08Evaluation of new bone resorption markers in a randomized comparison of pamidronate or clodronate for hypercalcemia of malignancy. ( Coleman, RE; Eastell, R; Guo, CY; Purohit, OP; Vinholes, J, 1997)
"We assessed the effects of 60-mg single doses of pamidronate disodium compared with saline alone in the treatment of cancer-associated hypercalcemia."5.07Treatment of cancer-associated hypercalcemia. Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone. ( Ahmann, F; Chapman, R; Gill, I; Gucalp, R; Heffernan, M; Knight, RD; Madajewicz, S; Navari, R; Theriault, R; Zelenakas, K, 1994)
"To determine the efficacy, dose-response relationship, and safety of 30, 60, and 90 mg of a single intravenous dose of an aminobisphosphonate, pamidronate (APD), for the treatment of moderate to severe hypercalcemia of malignancy."5.07Single-dose intravenous therapy with pamidronate for the treatment of hypercalcemia of malignancy: comparison of 30-, 60-, and 90-mg dosages. ( Chapman, R; Gagel, RF; Henderson, IC; Mallette, LE; Nussbaum, SR; Vandepol, CJ; Younger, J; Zubler, MA, 1993)
"We have conducted a randomized crossover comparative trial of a single-dose course of disodium (3-amino-1-hydroxypropylidene) bisphosphonate pentahydrate (pamidronate) and plicamycin in 48 patients with a first occurrence of tumor-related hypercalcemia."5.07Plicamycin and pamidronate in symptomatic tumor-related hypercalcemia: a prospective randomized crossover trial. ( Senn, HJ; Thiébaud, D; Thürlimann, B; Waldburger, R, 1992)
"This multicenter, double-blind, randomized trial was performed to determine the efficacy and safety of pamidronate disodium (APD) in comparison to etidronate disodium (EHDP) in the treatment of cancer-related hypercalcemia."5.07Comparative study of pamidronate disodium and etidronate disodium in the treatment of cancer-related hypercalcemia. ( Gucalp, R; Keller, A; Mallette, LE; Neidhart, J; Richman, SP; Ritch, P; Sarma, PR; Siegel, R; Tauer, K; Wiernik, PH, 1992)
"The improved efficacy of zoledronic acid compared with pamidronate disodium has been demonstrated in a pooled analysis of two randomized clinical trials in patients with hypercalcemia of malignancy."4.81The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy. ( Major, P, 2002)
"Two identical, concurrent, parallel, multicenter, randomized, double-blind, double-dummy trials were conducted to compare the efficacy and safety of zoledronic acid and pamidronate for treating hypercalcemia of malignancy (HCM)."4.81Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials. ( Abdi, E; Bell, R; Body, J; Hon, J; Lortholary, A; Major, P; Menssen, HD; Mills, G; Quebe-Fehling, E; Seaman, J; Yunus, F, 2001)
" They now constitute the standard treatment for cancer hypercalcemia, for which we recommend a dose of 1,500 mg of clodronate or 90 mg of pamidronate; the latter compound is more potent and has a longer lasting effect."4.80Current use of bisphosphonates in oncology. International Bone and Cancer Study Group. ( Bartl, R; Body, JJ; Burckhardt, P; Delmas, PD; Diel, IJ; Fleisch, H; Kanis, JA; Kyle, RA; Mundy, GR; Paterson, AH; Rubens, RD, 1998)
" In multiple myeloma, one study with oral clodronate has reported a decrease in bone events and two other studies, one with intravenous pamidronate and the other with oral clodronate have both reported a decrease in skeletal events and bone pain."4.80[Bisphosphonates and bone metastases]. ( Berthaud, P; Jadaud, E; Lortholary, A, 1999)
" Followed by hydration with saline, pamidronate is effective for the control of symptomatic hypercalcemia."4.79[Paraneoplastic syndrome]. ( Hara, N; Nakanishi, Y; Takayama, K, 1997)
"Recent information on the pathophysiology and treatment of hypercalcemia of malignancy is reviewed, and the roles of two new agents, gallium nitrate and pamidronate, are discussed."4.78Update on the medical treatment of hypercalcemia of malignancy. ( Hall, TG; Schaiff, RA, 1993)
"Salmon calcitonin has been used for the management of acute hypercalcemia for the past several years."4.78Salmon calcitonin in the acute management of hypercalcemia. ( Wisneski, LA, 1990)
"The primary objective was to compare the incidence of acute kidney injury (AKI) within 7 days of receiving pamidronate for the treatment of HCM with pre-existing renal dysfunction versus normal renal function at the time of pamidronate administration."4.02Use of Pamidronate for Hypercalcemia of Malignancy in Renal Dysfunction. ( Norman, SJ; Reeves, DJ; Saum, LM, 2021)
"No large study has been conducted to date to compare the effectiveness of prednisolone, alendronate and pamidronate as first-line treatment in children with hypercalcemia due to vitamin D intoxication."3.91Comparison of Treatment Regimens in Management of Severe Hypercalcemia Due to Vitamin D Intoxication in Children ( Anık, A; Atay, Z; Aycan, Z; Aydın, M; Bereket, A; Can Yılmaz, G; Çayır, A; Çetinkaya, S; Demir, K; Döneray, H; Eren, E; Kara, C; Kendirci, M; Orbak, Z; Özkan, B; Törel Ergür, A; Uçaktürk, A, 2019)
"This is a case report of a patient who developed severe, irreversible hypocalcemia after receiving one dose of pamidronate 90 mg for hypercalcemia of malignancy."3.91A case of severe, irreversible hypocalcemia after one dose of pamidronate administered for hypercalcemia of malignancy. ( Kim, S, 2019)
" Acute renal failure due to severe hypercalcemia and nephrocalcinosis treated with two doses of pamidronate in an infant with Williams-Beuren syndrome."3.88Acute renal failure due to severe hypercalcemia and nephrocalcinosis treated with two doses of pamidronate in an infant with Williams-Beuren syndrome. ( Baş, VN; Baştuğ, F; Çetinkaya, H; Nalçacıoğlu, H; Tekatlı-Çelik, B; Yel, S, 2018)
"Our results show that the majority of patients with breast cancer, who develop bony metastases in Newfoundland and Labrador, are initially treated with the bisphosphonate, pamidronate."3.79Use of bisphosphonates in metastatic breast cancer: single institution review at the Dr. H. Bliss Murphy Cancer Centre. ( Edwards, S; Laing, K; McCarthy, J; McCrate, F; Murphy, L; Powell, E; Seal, M, 2013)
"Pamidronate has a pharmacologic profile similar to that of etidronate, but pamidronate is more potent and has a longer duration of effect."3.77Pamidronate. ( Kellihan, MJ; Mangino, PD, 1992)
" We report a case in which a patient with tertiary hyperparathyroidism and refractory hypercalcemia who was not a surgical candidate was managed with the bisphosphonate pamidronate."3.75Hypercalcemia associated with tertiary hyperparathyroidism managed conservatively with pamidronate in a hemodialysis patient. ( Canada, RB; Czosnowski, LM; Hudson, JQ, 2009)
" Hypercalcemia and high serum level of calcitriol were found."3.74[Hypercalcaemia and malignant lymphoma. One case report]. ( Berrut, G; Foussard, C; Frein, D; Josselin, N; Lavigne, C; Moles, MP; Sivova, N, 2007)
" When conventional treatment of hypercalcemia failed, pamidronate dramatically decreased both the calcium levels and the frequency of uterine contractions."3.73Malignant hypercalcemia in pregnancy: effect of pamidronate on uterine contractions. ( Culbert, EC; Schfirin, BS, 2006)
"To describe extreme hypercalcemia as the presenting feature of acute lymphoblastic leukemia in an 8-yr-old girl and the combined use of pamidronate and calcitonin for its treatment."3.72Treatment of acute lymphoblastic leukemia-induced extreme hypercalcemia with pamidronate and calcitonin. ( Goldman, GM; Mathur, M; Rao, SP; Saxena, VR; Sykes, JA, 2003)
"The purpose of this study is to evaluate the acute effect of pamidronate on plasma ionized calcium (iCa) level reduction and dynamic parathyroid hormone (PTH) secretion in postmenopausal hemodialysis-dependent women with secondary hyperparathyroidism."3.72Acute effect of pamidronate on PTH secretion in postmenopausal hemodialysis patients with secondary hyperparathyroidism. ( Chu, P; Lin, SH; Lin, YF; Lu, KC; Yeung, LK, 2003)
"We commend the short-term use of pamidronate in neonatal severe hyperparathyroidism to treat extreme hypercalcaemia and halt hyperparathyroid-driven skeletal demineralisation in preparation for parathyroidectomy."3.72Neonatal severe hyperparathyroidism: genotype/phenotype correlation and the use of pamidronate as rescue therapy. ( Cheetham, T; Cranston, T; Kurzawinski, T; Pearce, S; Spitz, L; Thakker, R; van't Hoff, WG; Waller, S, 2004)
"To report the efficacy of Pamidronate to treat hypercalcaemia in a patient with Williams-Beuren syndrome (WBS)."3.72Long-term control of hypercalcaemia in an infant with williams-Beuren syndrome after a single infusion of biphosphonate (Pamidronate). ( Gravano, JC; Mastaglia, SR; Mautalen, C; Oliveri, B; Pardo Argerich, L, 2004)
"Treatment of immobilization hypercalcemia in these two patients with pamidronate was successful."3.71Immobilization hypercalcemia in critical illness following bariatric surgery. ( Alborzi, F; Leibowitz, AB, 2002)
"The most serious, potentially life-threatening manifestation of 'flare' is hypercalcemia, registered in 4-5% of breast cancer patients with bone metastases, usually during the first few weeks of tamoxifen treatment."3.71Tumor 'flare' hypercalcemia--an additional indication for bisphosphonates? ( Jelic, S; Mitrović, L; Nikolic-Tomasević, Z; Popov, I; Radosavljević, D, 2001)
"To determine whether pamidronate is a safe and effective agent for the treatment of severe hypercalcemia of malignancy in children."3.70Use of pamidronate in the management of acute cancer-related hypercalcemia in children. ( Shende, A; Young, G, 1998)
"Clodronate, etidronate and pamidronate are bisphosphonates introduced in the treatment of hypercalcaemia and osteoporosis."3.70Accumulation of bisphosphonates in human artery and their effects on human and rat arterial function in vitro. ( Kalliovalkama, J; Kankaanranta, H; Lähteenmäki, T; Pörsti, I; Salenius, JP; Sisto, T; Wu, X; Ylitalo, P; Ylitalo, R, 1998)
"Pamidronate disodium, a bone resorption inhibitor through osteoclast mediation, has been used to treat chronic hypercalcemia secondary to malignancy and chronic renal failure."3.70The use of pamidronate for hypercalcemia secondary to acute vitamin D intoxication. ( Lee, DC; Lee, GY, 1998)
"The successful use of pamidronate, a bisphosphonate, for the treatment of hypercalcemia and/or osteopenia is reported in three children with renal failure or following renal transplant."3.70The use of pamidronate in three children with renal disease. ( Rodd, C; Sellers, E; Sharma, A, 1998)
" He was treated with seven courses of combined chemotherapy (CDDP + etoposide), until he showed extreme hypercalcemia and acute renal failure."3.70[A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate]. ( Kametani, T; Koshida, H; Masuda, S, 1999)
"To review the use of pamidronate to treat immobilization hypercalcemia after acute spinal cord injury (SCI) in 9 cases."3.70Immobilization hypercalcemia treatment with pamidronate disodium after spinal cord injury. ( Cardenas, DD; Massagli, TL, 1999)
"To determine whether pamidronate disodium can reduce vitamin D3-induced hypercalcemia in dogs and whether combination treatment with calcitonin is more effective than treatment with pamidronate alone."3.70Use of pamidronate to reverse vitamin D3-induced toxicosis in dogs. ( Braselton, WE; Chiapuzio, CL; Fitzgerald, SF; Kaneene, JB; Kruger, JM; Nachreiner, RF; Rumbeiha, WK, 1999)
"Two patients with malignancy-associated hypercalcemia from bone metastases of breast cancer, accompanied by consciousness disturbance, were treated by a combination therapy of pamidronate and salmon calcitonin."3.70[Two cases of malignancy-associated hypercalcemia from bone metastases of breast cancer successfully treated with combination therapy using pamidronate and calcitonin]. ( Aoki, T; Kaise, H; Koyanagi, Y; Kusama, M; Matsunaga, T; Nakamura, Y; Nakayama, S; Ota, D, 2000)
" Pamidronate (Aredia(TM)) is the most widely evaluated bisphosphonate and is recommended for most patients with multiple myeloma or breast cancer with bone metastases."3.70Optimising treatment of bone metastases by Aredia(TM) and Zometa(TM). ( Coleman, RE, 2000)
"The purpose of this study was to investigate the effects of pamidronate, a second generation bisphosphonate, on the change in calcium homeostasis in patients with tumor-associated hypercalcemia."3.69Pamidronate treatment in patients with tumor-associated hypercalcemia: pharmacological effects and pharmacokinetics. ( Ariyoshi, Y; Hasegawa, H; Niinomi, M; Oiso, Y; Sakiyama, N; Takano, T; Tomita, A; Yamamoto, M, 1994)
"25 mmol/L external Ca2+, 200 mumol/L gallium nitrate inhibited PTH release from preparations of primary and uremic hyperparathyroidism by 14% and 22%, respectively."3.69Effects of the antihypercalcemic drugs gallium nitrate and pamidronate on hormone release of pathologic human parathyroid cells. ( Akerström, G; Gylfe, E; Rastad, J; Ridefelt, P, 1995)
"We reviewed our experience with pamidronate in 160 patients with tumour-induced hypercalcemia (TIH) persisting after rehydration, particularly the influence of the dose administered, the tumour type and the presence of bone metastatic involvement on the calcaemic and calciuric response to pamidronate therapy."3.69Treatment of tumour-induced hypercalcaemia with the bisphosphonate pamidronate: dose-response relationship and influence of tumour type. ( Body, JJ; Dumon, JC, 1994)
"Intravenous pamidronate disodium has been used successfully in the treatment of malignancy-associated hypercalcemia and Paget's disease of bone."3.69Intravenous pamidronate for hypercalcemia of primary hyperparathyroidism. ( Graves, L; Tal, A, 1996)
" This article presents a patient with hypoparathyroidism who was treated with calcium carbonate and calcitriol resulting in two admissions to the hospital for milk-alkali syndrome."3.69Milk-alkali syndrome induced by 1,25(OH)2D in a patient with hypoparathyroidism. ( Powers, K; Tal, A, 1996)
"Pamidronate (APD) is a drug widely used for the treatment of hypercalcemia of malignancy."3.69Safety of pamidronate in patients with renal failure and hypercalcemia. ( Flombaum, CD; Machado, CE, 1996)
" One of the earliest agents to be investigated, etidronate, is effective in the management of malignant hypercalcemia and, when used orally and intermittently, results in reduced bone loss in osteoporosis."3.69Role of bisphosphonates in prevention and treatment of bone metastases from breast cancer. ( Ashley, S; Hanson, J; Kanis, JA; McCloskey, E; Paterson, AH; Powles, TJ, 1995)
"A 65-year-old woman admitted for palliative care of metastatic renal/bladder carcinoma developed symptomatic hypocalcemia nine days following a single dose of pamidronate."3.69Symptomatic hypocalcemia after intravenous pamidronate. ( Bruera, E; McIntyre, E, 1996)
"Autopsy specimens of a bone metastasis from a woman with a primary squamous cell carcinoma of the tongue who developed multiple osteolytic lesions and hypercalcemia and was treated with pamidronate were studied histologically, histochemically, and ultrastructurally."3.69Effects of bisphosphonate (pamidronate) on bone resorption resulting from metastasis of a squamous cell carcinoma: report of an autopsy case and evaluation of bone resorbing activity in an experimental animal model. ( Hiraga, T; Nakajima, T; Ozawa, H; Takada, M, 1996)
"Pamidronate is a second generation bisphosphonate used for treating tumor-induced hypercalcemia and for preventing the development of new bone metastasis."3.69[Effect of pamidronate and interferon-alpha on bone and lung metastases and hypercalcemia in a patient with renal cell carcinoma]. ( Arima, K; Hioki, T; Kawamura, J; Kise, H; Kobayashi, K; Sugiura, Y; Tochigi, H; Yanagawa, M, 1996)
"The response to the bisphosphonate, pamidronate, is reported in a child with osteogenesis imperfecta who had recurrent symptomatic hypercalcaemia after immobilisation following fractures."3.69Hypercalcaemia in osteogenesis imperfecta treated with pamidronate. ( Ball, RJ; Smith, RA; Wilkinson, H; Williams, CJ, 1997)
"Hypercalcemia in a 4-year-old boy with non-Hodgkin lymphoma treated with pamidronate is presented."3.69Childhood cancer and hypercalcemia: report of a case treated with pamidronate. ( Akyüz, C; Büyükpamukçu, M; Hazar, V; Kutluk, MT; Varan, A, 1997)
" The time course study on the antihypercalcemic effect of pamidronate was performed using a rat hypercalcemia model induced by orally administered cholecalciferol."3.68Effect of pamidronate in a rat hypercalcemia model induced by cholecalciferol. ( Hasegawa, Y; Inukai, T; Noguchi, S; Okada, M, 1992)
"Pamidronate (aminopropylidene diphosphonate, APD) is known to be an effective agent in lowering plasma calcium in cancer associated hypercalcaemia and in primary hyperparathyroidism."3.68[Combination therapy with pamidronate and calcitonin in hypercalcemic crisis caused by primary hyperparathyroidism]. ( Christensen, JH; Kristiansen, JH, 1992)
"The effect of lowering ionized calcium on circulating parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) was assessed in twenty patients with hypercalcemia of malignancy following treatment with Pamidronate Disodium."3.68Circulating PTH and PTHrP levels before and after treatment of tumor induced hypercalcemia with Pamidronate Disodium (APD). ( Grill, V; Ho, PW; Jerums, G; Martin, TJ; Murray, RM; Pitt, P; Potts, C; Santamaria, JD, 1992)
"Nine patients (median age, 81 years) with primary hyperparathyroidism were treated with intravenous infusions of disodium pamidronate (APD), which is a bisphosphonate drug."3.68Disodium pamidronate in the preoperative treatment of hypercalcemia in patients with primary hyperparathyroidism. ( Jansson, S; Lindstedt, G; Lundberg, PA; Tisell, LE, 1991)
"Seventeen patients with malignant hypercalcemia were treated with a combination of a single dose of 3-amino 1-hydroxypropylidene-1-bisphosphonate (APD [also known as AHPrBP or palmidronate disodium]) and salmon calcitonin given as suppositories for 3 days."3.68Fast and effective treatment of malignant hypercalcemia. Combination of suppositories of calcitonin and a single infusion of 3-amino 1-hydroxypropylidene-1-bisphosphonate. ( Burckhardt, P; Jacquet, AF; Thiébaud, D, 1990)
"Glucocorticoids may be used as primary treatment when hypercalcemia is due to excessive intestinal calcium absorption (vitamin D intoxication, granulomatous disorders, some lymphomas)."2.82Hypercalcemia: A Review. ( Shane, E; Walker, MD, 2022)
"Pamidronate treatment also did not have any influence on patient survival or on the frequency of hypercalcaemia."2.69Failure of oral pamidronate to reduce skeletal morbidity in multiple myeloma: a double-blind placebo-controlled trial. Danish-Swedish co-operative study group. ( Abildgaard, N; Brincker, H; Ford, J; Gimsing, P; Hedenus, M; Kandra, A; Turesson, I; Westin, J, 1998)
" In a randomized phase III trial of 377 patients with multiple myeloma, Aredia was administered in a dosage of 90 mg i."2.68The role of bisphosphonates in the treatment of bone metastases--the U.S. experience. ( Harvey, HA; Lipton, A, 1996)
"Hypercalcemia of malignancy (HM) is one of the commonest metabolic complications associated with cancer."2.67Significance of plasma PTH-rp in patients with hypercalcemia of malignancy treated with bisphosphonate. ( Wimalawansa, SJ, 1994)
"Pamidronate was given in a single infusion on day 0, the dose of pamidronate adapted to the severity of hypercalcemia."2.67[Pamidronate in the treatment of tumor-associated hypercalcemia]. ( Bosse, C; Fortelny, A; Gerber, E; Janisch, S; Lenzhofer, R; Marosi, C; Pecherstorfer, M; Rainer, H; Schratzberger, W; Wogritsch, C, 1991)
"Thirty-three cancer patients remaining hypercalcemic after a 48-h rehydration period were included and monitored daily until normocalcemia or treatment failure was documented."2.66Aminohydroxypropylidene bisphosphonate (APD) treatment for tumor-associated hypercalcemia: a randomized comparison between a 3-day treatment and single 24-hour infusions. ( Body, JJ; Borkowski, A; Magritte, A; Sculier, JP; Seraj, F, 1989)
"Thirty-nine patients with cancer-associated hypercalcaemia were randomly allocated to receive aminohydroxypropylidene diphosphonate (APD), mithramycin, or corticosteroids and salmon calcitonin."2.66Comparison of aminohydroxypropylidene diphosphonate, mithramycin, and corticosteroids/calcitonin in treatment of cancer-associated hypercalcaemia. ( Boyle, IT; Cowan, RA; Dryburgh, FJ; Gardner, MD; Jenkins, AS; Ralston, SH, 1985)
"There was a significant reduction in pathological fractures and severe bone pain in the APD group, and hypercalcaemia was prevented."2.66Reduced morbidity from skeletal metastases in breast cancer patients during long-term bisphosphonate (APD) treatment. ( Beex, LV; Bijvoet, OL; Cleton, FJ; Elte, JW; Harinck, HI; Hermans, J; Kroon, HM; Neijt, JP; van Holten-Verzantvoort, AT; Vermey, P, 1987)
"Hypercalcemia is sustained by an inability of the kidney to deal efficiently with a chronically increased calcium load."2.66Role of bone and kidney in tumor-induced hypercalcemia and its treatment with bisphosphonate and sodium chloride. ( Bijvoet, OL; Body, JJ; Elte, JW; Harinck, HI; Neijt, JP; Plantingh, AS; Sleeboom, HP; Wildiers, J, 1987)
"Indomethacin was effective in only one of five patients to whom it was given, and EHDP was effective also in only one of five patients."2.65Comparative study of available medical therapy for hypercalcemia of malignancy. ( Heath, DA; Mundy, GR; Wilkinson, R, 1983)
"As hypercalcemia is a serious metabolic complication, a gradual dose reduction should be considered when interruption of high dose denosumab therapy is planned."2.61Acute hypercalcemia and excessive bone resorption following anti-RANKL withdrawal: Case report and brief literature review. ( Brazeau-Lamontagne, L; Dufresne, J; Huot Daneault, A; Massicotte, MH; Roux, S, 2019)
"Williams-Beuren syndrome (WBS) is a rare genetic disorder caused by the deletion of 26-28 genes on chromosome 7."2.50Importance of dietary calcium and vitamin D in the treatment of hypercalcaemia in Williams-Beuren syndrome. ( Geesing, CL; Hoenderop, JG; Lameris, AL; Schreuder, MF, 2014)
"Hypercalcemia has been described as a possible complication of many pediatric malignancies."2.45Hypercalcemia in pediatric acute megakaryocytic leukemia: case report and review of the literature. ( Ahmed, I; Cushing, B; Qayed, M; Rajpurkar, M; Valentini, RP, 2009)
"Pamidronate was given to treat hypercalcemia of unknown etiology."2.42Short-term, high-dose pamidronate-induced acute tubular necrosis: the postulated mechanisms of bisphosphonate nephrotoxicity. ( Asif, A; Banerjee, D; Bourgoignie, JJ; Preston, RA; Roth, D; Striker, L, 2003)
"Recurrent hypercalcemia is nevertheless difficult to control and antibodies against parathyroid hormone-related protein could be useful for that matter in selected patients who are not in the terminal stage of their disease."2.42Hypercalcemia of malignancy. ( Body, JJ, 2004)
"Zoledronic acid has also received the broadest regulatory approval of any bisphosphonate and can be used to treat HCM or bone lesions secondary to multiple myeloma and a wide variety of solid tumors, including breast, prostate, and lung cancers."2.42Safety and convenience of a 15-minute infusion of zoledronic acid. ( Berenson, J; Hirschberg, R, 2004)
"Hypercalcemia of malignancy (HCM) is a potentially life-threatening complication of cancer resulting from increased bone resorption by osteoclasts."2.41Treatment of hypercalcemia of malignancy with bisphosphonates. ( Berenson, JR, 2002)
"Myelomatosis is associated with considerable skeletal morbidity, particularly bone pain and fractures."2.41Bisphosphonates in multiple myeloma. ( Kanis, JA; McCloskey, EV, 2000)
"Specific treatment of cancer remains essential to prevent TIH relapse."2.41[Tumor-induced hypercalcemia. Review of bisphosphonate treatment]. ( Lortholary, A, 2001)
"Patients with breast cancer associated solely with osseous metastasis may live for a number of years."2.41Treatment of metastatic bone disease in breast cancer: bisphosphonates. ( Bastert, G; Diel, IJ; Solomayer, EF, 2000)
"Pamidronate (APD) is a potent inhibitor of bone resorption that is useful in the management of patients with osteolytic bone metastases from breast cancer or multiple myeloma, tumour-induced hypercalcaemia or Paget's disease of bone."2.40Pamidronate. A review of its use in the management of osteolytic bone metastases, tumour-induced hypercalcaemia and Paget's disease of bone. ( Coukell, AJ; Markham, A, 1998)
"We present a case of undifferentiated pancreatic cancer associated with humoral hypercalcemia of malignancy (HHM) in which parathyroid hormone-related protein (PTH-rP) is identified as the causative factor of hypercalcemia."2.40Undifferentiated pancreatic cancer associated with humoral hypercalcemia of malignancy. ( Higuchi, T; Kakizaki, S; Kitazawa, R; Mori, M; Nagamine, T; Ohya, N; Takagi, H; Takayama, H; Yoshinaga, T, 1998)
"This is particularly true in multiple myeloma (MM), where bone involvement markedly influences the quality of life of patients."2.40The role of bisphosphonates for the treatment of bone disease in multiple myeloma. ( Musto, P, 1998)
" Review of the published literature suggests that a clinically relevant dose-response relationship exists in the dose range 30-60 mg; most hypercalcemic patients will achieve normocalcemia with a dose of 60 mg pamidronate or more."2.39Progress in the treatment and palliation of advanced breast cancer: does the dose of pamidronate determine its effects? ( Thürlimann, B, 1994)
"Treatment of cancer associated hypercalcaemia is based on an initial phase of volume repletion with isotonic saline, followed by drug treatment to inhibit bone resorption."2.39Pathogenesis and management of cancer associated hypercalcaemia. ( Ralston, SH, 1994)
"The variability of different breast cancers in the susceptibility to metastatic bone disease is poorly understood."2.39Rationale for the use of bisphosphonates in breast cancer. ( Kanis, JA, 1996)
" Long term use of low-dose pamidronate in conjunction with conventional antiosteoporotic therapy may halt bone loss in steroid-induced and idiopathic osteoporosis."2.38Pamidronate. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease. ( Fitton, A; McTavish, D, 1991)
"Congenital mesoblastic nephroma is a rare pediatric renal tumor and has been reported in patients presenting with palpable abdominal mass, arterial hypertension, hematuria, polyuria, or hypercalcemia."1.72Severe neonatal hypercalcemia revealing congenital mesoblastic nephroma: A case report and management of neonatal hypercalcemia: Severe neonatal hypercalcemia revealing congenital mesoblastic nephroma. ( Bacchetta, J; Bordet, F; Dijoud, F; Duncan, A; Mure, PY; Pracros, JP; Tanné, C, 2022)
"This study demonstrates that Pam is effective and safe for treating PTHRH, while ensuring close laboratory monitoring of calcium and phosphorus metabolism."1.62Efficacy and Safety of Intravenous Pamidronate for Parathyroid Hormone-dependent Hypercalcemia in Hospitalized Patients. ( Barzilay-Yoseph, L; Klein, N; Ramaty, E; Rosenblum, RC; Rotman-Pikielny, P; Twito, O, 2021)
"BACKGROUND Hypercalcemia is a common complication in the intensive care unit (ICU)."1.48Use of Pamidronate to Treat Hypercalcemia in an Oncology Dialysis Patient: A Case Report. ( El Madhoun, I; El Zeer, HS; Khatib, M; Mahmoud, S; Mitwally, H, 2018)
"He had a prior diagnosis of autism and his mother had consulted an alternative therapist who had recommended many supplements, including calcium and vitamin D."1.43Severe hypercalcaemia in a child secondary to use of alternative therapies. ( Boyd, C; Moodambail, A, 2016)
"Hypercalcemia is a common complication of malignancy and portends a worse prognosis."1.40Approach to diagnosis and treatment of hypercalcemia in a patient with malignancy. ( Pani, A; Reagan, P; Rosner, MH, 2014)
"Primary hyperparathyroidism is characterised by high parathyroid hormone (PTH) levels and concomitant hypercalcaemia."1.40Exceptional localisation of an ectopic parathyroid adenoma at the level of the hyoid bone. ( Musters, L; Smit, C; van Ginhoven, TM, 2014)
"Pamidronate has a beneficial effect in those patients with IIH where glucocorticoids and furosemide fail to meet the expectations."1.39Intravenous pamidronate in the treatment of severe idiopathic infantile hypercalcemia. ( Bayer, M; Cerna, L; Konrad, M; Kutilek, S; Schlingmann, KP; Skalova, S, 2013)
"Hypercalcemia is mainly caused by bone resorption due to either secretion of cytokines including parathyroid hormone-related protein (PTHrP) or bone metastases."1.38Impact of chemotherapy on hypercalcemia in breast and lung cancer patients. ( Hassali, MA; Hassan, BA; Othman, SB; Weiderpass, E; Yusoff, ZB, 2012)
"Uterine leiomyomas are the most common pelvic tumor, and a frequent indication of the need for gynecologic surgery."1.37Severe hypercalcemia associated with uterine leiomyoma in pregnancy. ( Richardson, M; Spruill, L; Sullivan, S; Tarnawa, E; Underwood, P, 2011)
"Subcutaneous fat necrosis of the newborn (SCFN) is a panniculitis that develops in fatty areas during the first weeks of life after foetal distress or perinatal complications."1.35Effectiveness of pamidronate in severe neonatal hypercalcemia caused by subcutaneous fat necrosis: a case report. ( Bollani, L; Cabano, R; Del Forno, C; Lombardi, G; Stronati, M, 2009)
"For patients with HCM who do not achieve a response from bisphosphonates, or for those who need repeated dosing more often than expected, changing to a different drug class could be an alternative."1.35A case of resistant hypercalcemia of malignancy with a proposed treatment algorithm. ( Linneman, T; McMahan, J, 2009)
"Hypercalcemia is rare and when it is diagnosed, primary hyperparathyroidism should be ruled out."1.35[Paget's disease and hypercalcemia: coincidence or causal relationship?]. ( Altman, A; Green, I, 2009)
"Tumor-induced hypercalcemia is a frequent complication of advanced cancers, but it has been rarely reported in patients with sarcoma."1.34Tumor induced hypercalcemia in a patient with mediastinal synovial sarcoma. ( Badiei, Z; Hiradfar, M; Vakili, R; Zabolinejad, N, 2007)
"Pamidronate was well tolerated apart from one case of multifactorial renal failure."1.33Hypercalcemia and childhood cancer: a 7-year experience. ( Aerts, I; Chevret, L; Doz, F; Fattet, S; Garabedian, M; Kerdudo, C; Michon, J; Orbach, D; Pacquement, H, 2005)
"Hypercalcemia was induced either by sc inoculation of syngeneic colon (C-26) adenocarcinoma cells or by sc injection of high-dose recombinant PTHrP (0."1.33The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy. ( Adamu, S; Asuncion, F; Capparelli, C; Dunstan, CR; Geng, Z; Grisanti, M; Kostenuik, PJ; Morony, S; Starnes, C; Tan, HL; Warmington, K; Weimann, B, 2005)
"Treatments of hypercalcemia have included hydration, furosemide and corticosteroids."1.33Pamidronate: Treatment for severe hypercalcemia in neonatal subcutaneous fat necrosis. ( Alos, N; Chabot, G; Eugène, D; Fillion, M; Kokta, V; Powell, J, 2006)
"The frequency of bone metastases of breast cancer has been reported to be 65-75% of all breast cancer patients, and, in autopsy example at Shikoku Cancer Center, metastasis was recognized to be 74."1.33[The incidence and management of bone metastasis from breast cancer]. ( Fujiuchi, N; Ookubo, K; Saeki, T; Takeuchi, H, 2006)
"A patient with multiple myeloma who developed hypercalcemia during three different stages of his disease, with a different hypercalcemic agent elevated in his serum on each occasion, is described."1.32Hypercalcemia due to sun exposure in a patient with multiple myeloma and elevated parathyroid hormone-related protein. ( Bergi-Stamatelou, M; Karga, H; Papapetrou, PD; Thanou, S, 2003)
"The pamidronate dose was increased to 60 mg once a week and was well tolerated."1.32Pamidronate in a girl with chronic renal insufficiency dependent on parenteral nutrition. ( Chesney, RW; Duke, JL; Frizzell, NK; Hak, EB; Jones, DP, 2003)
"By inhibiting bone resorption, bisphosphonate administration caused transient normalization of calcemia, associated with improved FIM, at a significantly higher level than in untreated patients (+16."1.32A single bisphosphonate infusion is associated with improved functional capacity in elderly subjects with primary hyperparathyroidism. ( Ammann, P; Herter-Clavel, C; Lubrano, A; Rizzoli, R, 2003)
"The use of pamidronate for treatment of hypercalcemia and chronic conditions that affect normal bone growth is increasing in children."1.32Pamidronate treatment for hypercalcemia in an infant receiving parenteral nutrition. ( Bryowsky, JJ; Bugnitz, MC; Hak, EB, 2004)
"Zoledronic acid (6i) has thus been selected for clinical development under the registered trade name Zometa."1.31Highly potent geminal bisphosphonates. From pamidronate disodium (Aredia) to zoledronic acid (Zometa). ( Bachmann, R; Bisping, M; Born, AR; Cortesi, R; Glatt, M; Green, JR; Guiglia, G; Jaeggi, KA; Jeker, H; Klein, R; Müller, K; Ramseier, U; Schmid, J; Schreiber, G; Seltenmeyer, Y; Widler, L, 2002)
"Hypercalcemia is a serious complication of malignancies, but it is uncommon in acute leukemia."1.31Megakaryoblastic transformation of polycythemia vera with hypercalcemia. ( Iwasaki, H; Kurosawa, M, 2002)
"Although treatment of hypercalcemia with pamidronate is palliative, it is effective against the deterioration of quality of life."1.31[Treatment of hypercalcemia of malignancy with pamidronate in a patient with advanced recurrent oral cancer]. ( Hashitani, S; Matsushita, Y; Nishimura, N; Noguchi, K; Takaoka, K; Urade, M, 2002)
"Treatment with pamidronate (Aredia) was successful and reduced the serum calcium to normal values."1.31[Immobilization hypercalcemia as a complication of polyneuropathy]. ( Block, F; Brandenburg, VM; Dietrich, CG; Riehl, J, 2000)
"We report on a patient with parathyroid carcinoma with hypercalcaemia and pulmonary metastases, treated with pamidronate and radiotherapy and later with surgery."1.31Positive effect of radiotherapy and surgery on hormonally active pulmonary metastases of primary parathyroid carcinoma. ( Boquist, L; Kristoffersson, A; Rasmuson, T, 2000)
"Hypercalcemia was defined as a serum Ca concentration higher than 11 mg/dl of the correction for serum albumin concentration."1.31Hypercalcemia in patients with oral squamous cell carcinoma. ( Iwase, M; Kakuta, S; Kurachi, Y; Nagumo, M; Nakamura-Mitsuhashi, M; Sakamaki, H, 2001)
"We report a male patient with advanced AIDS who developed hypercalcemia 2 weeks after institution of rhGH therapy."1.30Hypercalcemia in an AIDS patient treated with growth hormone. ( Hartzband, P; Lally, M; Sakoulas, G; Tritos, NA; Wanke, C, 1997)
"Tumor-induced osteolysis is essentially mediated by the osteoclasts whose number and activity appear to be stimulated under the influence of tumor secretory products."1.30[Bone metastases: pathogenesis and treatment with diphosphonates]. ( Body, JJ, 1997)
"The hypercalcemia was refractory to extensive hydration and calcitonin, but was ameliorated by pamidronate."1.30Hypercalcemia in an euthyroid patient with secondary hypoadrenalism and diabetes insipidus due to hypothalamic tumor. ( Demura, H; Hotta, M; Sato, K; Shibasaki, T, 1998)
"In those patients in whom systemic anti-cancer therapy is available, treatment with APD improves survival, but in all other patients the primary aim of treatment should be symptom control."1.29Analysis of survival following treatment of tumour-induced hypercalcaemia with intravenous pamidronate (APD). ( A'Hern, RP; Hardy, JR; Ling, PJ, 1995)
"Pamidronate therapy was effective in restoring serum calcium to normal."1.29Hypercalcaemia in primary oxalosis: role of increased bone resorption and effects of treatment with pamidronate. ( Barnes, ND; Compston, JE; Grant, J; Jamieson, N; Noble-Jamieson, G; Yamaguchi, K, 1995)
"Alendronate is an aminobisphosphonate that acts as a potent inhibitor of osteoclastic bone resorption."1.29Alendronate distributed on bone surfaces inhibits osteoclastic bone resorption in vitro and in experimental hypercalcemia models. ( Azuma, Y; Kiyoki, M; Ohta, T; Okabe, K; Oue, Y; Sato, H; Tsuchimoto, M, 1995)
"Pamidronate was given to 10 patients with end stage renal failure who had become symptomatically hypercalcaemic due to the use of calcium based phosphate binders and alphacalcidol."1.29Treatment of hypercalcaemia with pamidronate in patients with end stage renal failure. ( Davenport, A; Goel, S; Mackenzie, JC, 1993)
"Breast cancers were more common in group N, squamous cell cancers predominated in group E (p < 0."1.29Parathyroid hormone-related protein and life expectancy in hypercalcemic cancer patients. ( Baumgartner, G; Blind, E; Pecherstorfer, M; Raue, F; Schilling, T; Ziegler, R; Zimmer-Roth, I, 1994)
"Parathyroid carcinoma is rare and the associated hypercalcaemia is often resistant to all treatment."1.29Prolonged remission of hypercalcaemia due to parathyroid carcinoma with pamidronate. ( Braatvedt, GD; Corrall, RJ; Newrick, PG; Sheffield, E; Webb, AJ, 1994)
"Primary hyperparathyroidism is usually associated with normal or elevated serum 1,25-dihydroxyvitamin D [1,25(OH)2D] levels."1.29Inhibition of 1,25(OH)2D production by hypercalcemia in osteitis fibrosa cystica: influence on parathyroid hormone secretion and hungry bone disease. ( Brossard, JH; D'Amour, P; Garon, J; Gascon-Barré, M; Lepage, R, 1993)
"A 57-year-old man with lung squamous cell carcinoma revealed hypercalcemia, hypophosphoremia, elevation of nephrogenous cAMP and metabolic alkalosis."1.29A case of squamous cell lung carcinoma with high concentration of parathyroid hormone-related peptide in serum and pleural effusion presenting hypercalcemia. ( Haji, M; Hara, N; Ichinose, Y; Iguchi, H; Katakami, H; Nawata, H; Nishi, Y; Ohta, M; Tanaka, S, 1993)
"Pamidronate treatment resulted in a brisk reduction in plasma calcium concentration."1.29Vitamin D intoxication causes hypercalcaemia by increased bone resorption which responds to pamidronate. ( Davies, M; Marks, JS; Mawer, EB; Selby, PL, 1995)
" Patients received, on average, 30 mg less pamidronate than that given in the manufacturer's dosing schedule."1.29An audit of the management of malignant hypercalcaemia. ( Dodwell, DJ; Gerrard, GE; Overend, MA; Vail, A; Watters, J, 1996)
"Pamidronate has been demonstrated to be an effective agent in the treatment of cancer-associated hypercalcaemia."1.28A comparison of low versus high dose pamidronate in cancer-associated hypercalcaemia. ( Boyle, IT; Cowan, RA; Dryburgh, FJ; Fraser, WD; Gallacher, SJ; Logue, FC; Ralston, SH, 1991)
" The author discusses the administration, dosage and side effects, and results of current studies."1.28Bisphosphonate treatment of bone metastases and hypercalcemia of malignancy. ( Coleman, RE, 1991)
"The rat Walker carcinosarcoma 256 is an animal model for humoral hypercalcaemia of malignancy (HHM)."1.28Relative role of bone and kidney in the hypercalcaemia associated with the rat Walker carcinosarcoma 256. ( Esbrit, P; Hurtado, J; Rapado, A, 1991)
"Life expectancy is poor in cancer-associated hypercalcemia even in patients who are actively treated."1.28Cancer-associated hypercalcemia: morbidity and mortality. Clinical experience in 126 treated patients. ( Boyle, IT; Campbell, J; Gallacher, SJ; Patel, U; Ralston, SH, 1990)
"A 10-year-old boy with leukaemia-associated hypercalcaemia was treated with aminohydroxypropylidene biphosphonate (AHPrBP previously APD) in a total dosage of 60 mg over 5 days, when the condition failed to respond to rehydration and frusemide and no sustained effect was produced by haemodialysis with a calcium (Ca)-free dialysate."1.28Leukaemia-associated hypercalcaemia in a 10-year-old boy: effectiveness of aminohydroxypropylidene biphosphonate. ( Boudailliez, BR; Kremp, O; Pautard, BJ; Piussan, CX; Sebert, JL, 1990)
"Retreatment with pamidronate again resulted in normocalcaemia."1.28Immobilization-related hypercalcaemia--a possible novel mechanism and response to pamidronate. ( Allam, BF; Boyce, BF; Boyle, IT; Dryburgh, FJ; Gallacher, SJ; Logue, FC; Ralston, SH, 1990)
"While patients with renal osteodystrophy react favorably to supplementation of active vitamin D metabolites to prevent or reverse renal osteodystrophy, the use of these drugs is bound to result in greater hypercalcemia in those patients who are already hypercalcemic."1.28No effect of APD (amino hydroxypropylidene bisphosphonate) on hypercalcemia in patients with renal osteodystrophy. ( de bos Kuil, RJ; Dorhout Mees, EJ; Duursma, SA; Hené, RJ; Raymakers, JA; Visser, WJ, 1990)
"Malignant hypercalcemia is caused by both increased bone resorption and enhanced tubular reabsorption of calcium."1.28Response to retreatment of malignant hypercalcemia with the bisphosphonate AHPrBP (APD): respective role of kidney and bone. ( Burckhardt, P; Jaeger, P; Thiebaud, D, 1990)
"There were seven patients with breast cancer, eight with lung cancer, and ten with a variety of other cancers."1.28Single high-dose (45 mg) infusions of aminohydroxypropylidene diphosphonate for severe malignant hypercalcemia. ( Cantwell, BM; Carmichael, J; Harris, AL; Mannix, KA, 1989)
"Eight patients with cancer associated hypercalcaemia were treated with the combination of aminohydroxypropylidene diphosphonate and salmon calcitonin for six days."1.27Treatment of cancer associated hypercalcaemia with combined aminohydroxypropylidene diphosphonate and calcitonin. ( Alzaid, AA; Boyle, IT; Gardner, MD; Ralston, SH, 1986)
" In order to establish a dose-response in humans, patients were divided into four groups receiving 30 mg, 45 mg, 60 mg, or 90 mg, respectively, as a 24-hour infusion."1.27Dose-response in the treatment of hypercalcemia of malignancy by a single infusion of the bisphosphonate AHPrBP. ( Burckhardt, P; Jacquet, AF; Jaeger, P; Thiébaud, D, 1988)
"The hypercalcemia was corrected by a single intravenous dose of (3-amino-1-hydroxypropylidene)-1,1-diphosphonate (15 mg), allowing parathyroidectomy to be performed electively and on a well patient."1.27Aminohydroxypropylidene diphosphonate treatment of hypercalcemic crisis due to primary hyperparathyroidism. ( Evans, RA, 1987)
" AHPrBP was given as two-hour daily infusions for three days, and three different patients were treated at each of the six following dosage levels: 0."1.27Dose/response study of aminohydroxypropylidene bisphosphonate in tumor-associated hypercalcemia. ( Body, JJ; Borkowski, A; Klastersky, J; Pot, M; Sculier, JP, 1987)

Research

Studies (311)

TimeframeStudies, this research(%)All Research%
pre-199047 (15.11)18.7374
1990's146 (46.95)18.2507
2000's77 (24.76)29.6817
2010's35 (11.25)24.3611
2020's6 (1.93)2.80

Authors

AuthorsStudies
Widler, L1
Jaeggi, KA1
Glatt, M1
Müller, K1
Bachmann, R1
Bisping, M1
Born, AR1
Cortesi, R1
Guiglia, G1
Jeker, H1
Klein, R1
Ramseier, U1
Schmid, J1
Schreiber, G1
Seltenmeyer, Y1
Green, JR1
Zubair Ullah, HM1
Surya, A1
Morley, N1
Ahmad, S1
Tanné, C1
Pracros, JP1
Dijoud, F1
Mure, PY1
Bordet, F1
Duncan, A1
Bacchetta, J1
Shulman, R1
Geara, AS1
Berns, JS1
Walker, MD1
Shane, E1
Norman, SJ1
Reeves, DJ1
Saum, LM1
Satyarengga, M1
Silver, KD1
Rosenblum, RC1
Twito, O1
Barzilay-Yoseph, L1
Ramaty, E1
Klein, N1
Rotman-Pikielny, P1
Arif, H1
Beg, M1
Zahid, S1
Sial, M1
Talwar, A1
Christou, A1
Babich, M1
Basok, AB1
Rogachev, B1
Haviv, YS1
Vorobiov, M1
Ellis, S1
Tsiopanis, G1
Lad, T1
Mahmoud, S1
Mitwally, H1
El Zeer, HS1
El Madhoun, I1
Khatib, M1
Baştuğ, F1
Nalçacıoğlu, H1
Baş, VN1
Tekatlı-Çelik, B1
Çetinkaya, H1
Yel, S1
Demir, K1
Döneray, H1
Kara, C1
Atay, Z1
Çetinkaya, S1
Çayır, A1
Anık, A1
Eren, E1
Uçaktürk, A1
Can Yılmaz, G1
Törel Ergür, A1
Kendirci, M1
Aycan, Z1
Bereket, A1
Aydın, M1
Orbak, Z1
Özkan, B1
Kim, S1
Roux, S1
Massicotte, MH1
Huot Daneault, A1
Brazeau-Lamontagne, L1
Dufresne, J1
Haykal, T1
Sundus, S1
Bachuwa, G1
Danish, R1
Arango, ML1
Shah, AN1
Hooman, N1
Skalova, S1
Cerna, L1
Bayer, M1
Kutilek, S1
Konrad, M1
Schlingmann, KP1
Reagan, P1
Pani, A1
Rosner, MH1
Boumans, D1
de Vries, PA1
Rikken, NE1
Laverman, GD1
Guarino, S1
Marzuillo, P1
Apicella, A1
Annicchiarico Petruzzelli, L1
La Manna, A1
Lameris, AL1
Geesing, CL1
Hoenderop, JG1
Schreuder, MF1
Musters, L1
van Ginhoven, TM1
Smit, C1
Pittaway, JF1
Srirangalingam, U1
Hanson, PL1
Jones, P1
Drake, WM1
Ismail, J1
Wright, JD1
Tergas, AI1
Ananth, CV1
Burke, WM1
Hou, JY1
Chen, L1
Neugut, AI1
Richards, CA1
Hershman, DL1
Liao, M1
Magcalas, P1
Hopkins-Braddock, P1
Patnaik, S1
Lai, YK1
Boyd, C1
Moodambail, A1
Lombardi, G1
Cabano, R1
Bollani, L1
Del Forno, C1
Stronati, M1
Lombet, J1
Auron, A1
Tal, L1
Srivastava, T1
Alon, US1
Pao, VY1
Chang, S1
Shoback, DM1
Bikle, DD1
Czosnowski, LM1
Hudson, JQ1
Canada, RB1
Qayed, M1
Ahmed, I1
Valentini, RP1
Cushing, B1
Rajpurkar, M1
Labossiere, R1
Hintzke, C1
Ileana, S1
McMahan, J1
Linneman, T1
Green, I1
Altman, A1
Bergstein, KR1
Jacobsen, RB1
Jacobsen, BB1
Christesen, HT1
ten Dam, MA1
Hilbrands, LB1
Wetzels, JF1
Whitney, JL1
Barrs, VR1
Wilkinson, MR1
Briscoe, KA1
Beatty, JA1
Tarnawa, E1
Sullivan, S1
Underwood, P1
Richardson, M1
Spruill, L1
Ludwig, H1
Zojer, N1
Sangun, O1
Dundar, BN1
Erdogan, E1
Legrand, SB1
Hoi, WH1
Leow, MK1
Sule, A1
Lee, HY1
Mmed, TA1
Tay, JC1
Shimizu, H1
Monden, T1
Tomotsune, T1
Nakatani, Y1
Domeki, N1
Matsumura, M1
Jojima, T1
Kawagoe, Y1
Kasai, K1
Hassan, BA1
Yusoff, ZB1
Hassali, MA1
Othman, SB1
Weiderpass, E1
Murphy, L1
McCarthy, J1
McCrate, F1
Laing, K1
Powell, E1
Seal, M1
Edwards, S1
Kurosawa, M1
Iwasaki, H1
Major, P2
Nishimura, N1
Matsushita, Y1
Takaoka, K1
Hashitani, S1
Noguchi, K1
Urade, M1
Major, PP1
Cook, R1
Alborzi, F1
Leibowitz, AB1
Berenson, JR2
Papapetrou, PD1
Bergi-Stamatelou, M1
Karga, H1
Thanou, S1
Mathur, M1
Sykes, JA1
Saxena, VR1
Rao, SP1
Goldman, GM1
Duke, JL1
Jones, DP1
Frizzell, NK1
Chesney, RW1
Hak, EB2
Torregrosa, JV1
Moreno, A1
Mas, M1
Ybarra, J1
Fuster, D1
Banerjee, D1
Asif, A1
Striker, L1
Preston, RA1
Bourgoignie, JJ1
Roth, D1
Pecherstorfer, M5
Steinhauer, EU1
Rizzoli, R3
Wetterwald, M1
Bergström, B1
Duncan, AR1
Kato, A1
Shinozaki, S1
Goga, T1
Hishida, A1
Musto, P2
Falcone, A1
Sanpaolo, G1
Bodenizza, C1
Cascavilla, N1
Melillo, L1
Scalzulli, PR1
Dell'Olio, M1
La Sala, A1
Mantuano, S1
Nobile, M1
Carella, AM1
Lu, KC1
Yeung, LK1
Lin, SH2
Lin, YF1
Chu, P1
Atula, ST1
Tähtelä, RK1
Nevalainen, JI1
Pylkkänen, LH1
Ezgu, FS1
Buyan, N1
Gündüz, M1
Tümer, L1
Okur, I1
Hasanoglu, A1
Caldwell, JW1
Arsura, EL1
Kilgore, WB1
Reddy, CM1
Johnson, RH1
Body, JJ16
Ammann, P2
Herter-Clavel, C1
Lubrano, A1
Wenzel, C1
Bartsch, R1
Hussian, D1
Pluschnig, U1
Locker, GJ1
Sevelda, U1
Zielinski, CC1
Steger, GG1
Berenson, J1
Hirschberg, R1
Waller, S1
Kurzawinski, T1
Spitz, L1
Thakker, R1
Cranston, T1
Pearce, S1
Cheetham, T1
van't Hoff, WG1
Bryowsky, JJ1
Bugnitz, MC1
Oliveri, B1
Mastaglia, SR1
Mautalen, C1
Gravano, JC1
Pardo Argerich, L1
Díaz, C1
Soutelo, MJ1
Quiroga, L1
Palmer, L1
Lutfi, R1
Cagle, AP1
Waguespack, SG1
Buckingham, BA1
Shankar, RR1
Dimeglio, LA1
Jansson, S3
Morgan, E1
Kerdudo, C2
Aerts, I2
Fattet, S2
Chevret, L2
Pacquement, H2
Doz, F2
Michon, J2
Garabedian, M2
Orbach, D2
Morony, S1
Warmington, K1
Adamu, S1
Asuncion, F1
Geng, Z1
Grisanti, M1
Tan, HL1
Capparelli, C1
Starnes, C1
Weimann, B1
Dunstan, CR1
Kostenuik, PJ1
Balla, J1
Lugassy, G1
Waterfield, KE1
Lee, MA1
Regnard, CF1
Duque, G1
Segal, R1
Wise, F1
Bianco, J1
Tavil, B1
Sipahi, T1
Kara, A1
Pastor-Zuazaga, D1
Garatea-Crelgo, J1
Martino-Gorbea, R1
Etayo-Pérez, A1
Sebastián-López, C1
Klomp, CM1
van den Broek, MW1
Buijs, J1
Beekman, R1
Alos, N1
Eugène, D1
Fillion, M1
Powell, J1
Kokta, V1
Chabot, G1
Cheng, CJ1
Chou, CH1
Diaz-Borjon, A1
Seyler, TM1
Chen, NL1
Lim, SS1
Saeki, T1
Ookubo, K1
Takeuchi, H1
Fujiuchi, N1
Trimarchi, H1
Lombi, F1
Forrester, M1
Elizondo, C1
Sawinski, D1
Pereyra, H1
Freixas, E1
Culbert, EC1
Schfirin, BS1
Griz, L1
Colares, V1
Bandeira, F1
Beckers, MM1
Slee, PH1
Frein, D1
Lavigne, C1
Josselin, N1
Foussard, C1
Sivova, N1
Moles, MP1
Berrut, G1
Manouras, A1
Toutouzas, KG1
Markogiannakis, H1
Lagoudianakis, E1
Papadima, A1
Antonakis, PT1
Kafiri, G1
Bramis, I1
Vakili, R1
Hiradfar, M1
Zabolinejad, N1
Badiei, Z1
Chatterjee, M1
Speiser, PW1
Sleeboom, HP4
Bijvoet, OL7
van Oosterom, AT2
Gleed, JH2
O'Riordan, JL2
Mundy, GR3
Wilkinson, R1
Heath, DA2
Tubiana-Hulin, M1
de Vernejoul, MC1
Brière, M1
Miravet, L1
Clavel, B1
Delmas, PD3
Meunier, PJ1
Schürer, CC1
Peters, U1
Fischer, JT1
van Breukelen, FJ1
Frijlink, WB1
Mulder, H1
Thürlimann, B2
Purohit, OP2
Radstone, CR1
Anthony, C1
Kanis, JA6
Coleman, RE6
Ling, PJ1
A'Hern, RP1
Hardy, JR1
Macro, M1
Bouvard, G1
Le Gangneux, E1
Colin, T1
Loyau, G1
Oiso, Y1
Tomita, A1
Hasegawa, H1
Ariyoshi, Y1
Niinomi, M1
Yamamoto, M1
Takano, T1
Sakiyama, N1
Solomon, CG1
Dluhy, RG1
Tamion, F1
Bonmarchand, F1
Girault, C1
Chevron, V1
Leroy, J1
Yamaguchi, K1
Grant, J1
Noble-Jamieson, G1
Jamieson, N1
Barnes, ND1
Compston, JE1
Azuma, Y1
Sato, H1
Oue, Y1
Okabe, K1
Ohta, T1
Tsuchimoto, M1
Kiyoki, M1
Ridefelt, P1
Gylfe, E1
Akerström, G1
Rastad, J1
Wimalawansa, SJ2
Anand, A1
Anand, N1
Sato, K2
Imaki, T1
Toraya, S1
Demura, H2
Tanaka, M1
Kasajima, T1
Takeuchi, A1
Kobayashi, T1
Walls, J1
Ratcliffe, WA1
Howell, A4
Bundred, NJ1
Budayr, AA1
Zysset, E1
Jenzer, A1
Thiébaud, D11
Jaquet-Müller, F1
Bonjour, JP1
Gertz, B1
Burckhardt, P10
Gucalp, R2
Theriault, R2
Gill, I1
Madajewicz, S1
Chapman, R2
Navari, R1
Ahmann, F1
Zelenakas, K1
Heffernan, M3
Knight, RD4
Dumon, JC4
Kotzmann, H1
Svoboda, T1
Bernecker, P1
Clodi, M1
Woloszczuk, W1
Niederle, B1
Waldhäusl, W1
Luger, A1
Gurney, H2
Grill, V2
Martin, TJ3
Davenport, A1
Goel, S1
Mackenzie, JC1
Schilling, T2
Blind, E2
Zimmer-Roth, I1
Baumgartner, G1
Ziegler, R2
Raue, F2
Newrick, PG1
Braatvedt, GD1
Webb, AJ1
Sheffield, E1
Corrall, RJ1
Ishimura, E1
Miki, T1
Koyama, H1
Harada, K1
Nakatsuka, K1
Inaba, M1
Nishizawa, Y1
Morii, H1
Brossard, JH1
Garon, J1
Lepage, R1
Gascon-Barré, M1
D'Amour, P1
Lichinitser, MR1
Vyshinskaia, GV1
Kupchan, DZ1
Liubimova, NV1
Profumo, RJ1
Reese, JC1
Foy, TM1
Garibaldi, LR1
Kane, RE1
Thirion, M1
Cleeren, A3
Nussbaum, SR1
Younger, J1
Vandepol, CJ1
Gagel, RF1
Zubler, MA1
Henderson, IC1
Mallette, LE2
Grutters, JC1
Hermus, AR1
de Mulder, PH1
Beex, LV2
Leidig, G1
Hall, TG1
Schaiff, RA1
Rosenmund, A1
Kinirons, MT1
Iguchi, H2
Katakami, H1
Ichinose, Y1
Nishi, Y1
Tanaka, S1
Hara, N2
Ohta, M1
Haji, M1
Nawata, H1
Carbone, LD1
Land, MA1
Stentz, FB1
Palmieri, GM1
Selby, PL1
Davies, M2
Marks, JS1
Mawer, EB1
Lichtenstein, A1
Porter, L2
Dimopoulos, MA1
Bordoni, R1
George, S1
Lipton, A6
Keller, A2
Ballester, O1
Kovacs, MJ1
Blacklock, HA1
Bell, R2
Simeone, J2
Reitsma, DJ2
Seaman, J3
Nesković-Konstantinović, Z1
Mitrović, L2
Petrović, J1
Stamatović, L1
Ristović, Z1
Ralston, SH13
Tal, A2
Graves, L1
Powers, K1
Gerrard, GE1
Dodwell, DJ3
Vail, A1
Watters, J1
Overend, MA1
Machado, CE1
Flombaum, CD1
Harvey, HA1
Stewart, GO1
Stuckey, BG1
Ward, LC1
Prince, RL1
Gutteridge, DH1
Constable, IJ1
Paterson, AH2
Powles, TJ1
McCloskey, E1
Hanson, J1
Ashley, S1
McIntyre, E1
Bruera, E1
Illidge, TM1
Hussey, M1
Godden, CW1
Hiraga, T1
Takada, M1
Nakajima, T1
Ozawa, H1
Possinger, K1
Flath, B1
Akrivakis, K1
Hortobagyi, GN2
Theriault, RL2
Blayney, D1
Sinoff, C1
Wheeler, H1
Simeone, JF1
Kise, H1
Kobayashi, K1
Arima, K1
Yanagawa, M1
Tochigi, H1
Kawamura, J1
Hioki, T1
Sugiura, Y1
Ford, JF1
Green, J1
Vinholes, J1
Guo, CY1
Eastell, R1
Piccart, M1
Williams, CJ1
Smith, RA1
Ball, RJ1
Wilkinson, H1
MacConnachie, AM1
Malnick, SD1
Ariel-Ronen, S1
Evron, E1
Sthoeger, ZM1
Reading, PJ1
Newman, PK1
Kelly, WF1
Bateson, MC1
Rothwell, P1
Sinha, RN1
Fraser, WD5
Casson, IF1
Kutluk, MT1
Hazar, V1
Akyüz, C3
Varan, A2
Büyükpamukçu, M2
Sakoulas, G1
Tritos, NA1
Lally, M1
Wanke, C1
Hartzband, P1
Nakanishi, Y1
Takayama, K1
Young, G1
Shende, A1
Kedlaya, D1
Brandstater, ME1
Lee, JK1
Coukell, AJ1
Markham, A1
Greenwald, RA1
Stein, B1
Miller, F1
Kutluk, T2
Yalçin, B2
Büyükpamuküçu, M1
Brincker, H1
Westin, J1
Abildgaard, N1
Gimsing, P1
Turesson, I1
Hedenus, M1
Ford, J1
Kandra, A1
Westphal, SA1
Endo, K1
Katsumata, K1
Kubodera, N1
Teramoto, T1
Ikeda, K1
Fujita, T1
Ogata, E1
Lteif, AN1
Zimmerman, D1
Ylitalo, R1
Kalliovalkama, J1
Wu, X1
Kankaanranta, H1
Salenius, JP1
Sisto, T1
Lähteenmäki, T1
Ylitalo, P1
Pörsti, I1
Kakizaki, S1
Ohya, N1
Yoshinaga, T1
Higuchi, T1
Kitazawa, R1
Takayama, H1
Takagi, H1
Nagamine, T1
Mori, M1
Loh, K1
Matthay, KK1
Hoover, M1
Bracho, FA1
Cortez, AB1
Conte, FA1
Albanese, CT1
Miller, TR1
Price, DC1
Flores, AJ1
Kaviani, A1
Shoback, D1
Bartl, R1
Diel, IJ2
Fleisch, H2
Kyle, RA1
Rubens, RD2
Lee, DC1
Lee, GY1
Sellers, E1
Sharma, A1
Rodd, C1
Sims, EC1
Rogers, PB1
Besser, GM1
Plowman, PN1
Leff, R1
Glück, S1
Stewart, JF1
Costello, S1
Kennedy, I1
Seaman, JJ1
Mellars, K1
Attard, TM1
Dhawan, A1
Kaufman, SS1
Collier, DS1
Langnas, AN1
Hotta, M1
Shibasaki, T1
Cila, A1
Koshida, H1
Kametani, T1
Masuda, S1
De Schepper, J1
de Pont, S1
Smitz, J1
De Coster, D1
Schots, R1
Otten, J1
Massagli, TL1
Cardenas, DD1
Rumbeiha, WK1
Kruger, JM1
Fitzgerald, SF1
Nachreiner, RF1
Kaneene, JB1
Braselton, WE1
Chiapuzio, CL1
Lortholary, A4
Jadaud, E1
Berthaud, P1
Tezer Kutluk, M1
Kusama, M1
Kaise, H1
Nakayama, S1
Ota, D1
Aoki, T1
Koyanagi, Y1
Matsunaga, T1
Nakamura, Y1
McCloskey, EV1
Felsenfeld, AJ1
Jara, A1
Avedian, G1
Kleeman, CR1
Louviaux, I1
Riehl, J1
Brandenburg, VM1
Dietrich, CG1
Block, F1
Akbulut, H1
Icli, F1
Rasmuson, T1
Kristoffersson, A1
Boquist, L1
Hon, J1
Abdi, E1
Mills, G1
Menssen, HD1
Yunus, F1
Body, J1
Quebe-Fehling, E1
Nikolic-Tomasević, Z1
Jelic, S1
Popov, I1
Radosavljević, D1
Khan, N1
Licata, A1
Rogers, D1
Iwase, M1
Kurachi, Y1
Kakuta, S1
Sakamaki, H1
Nakamura-Mitsuhashi, M1
Nagumo, M1
Shanks, D1
Linke, R1
Saxon, B1
Solomayer, EF1
Bastert, G1
Ostenstad, B1
Andersen, OK1
Okada, M1
Noguchi, S1
Hasegawa, Y1
Inukai, T1
Gallacher, SJ8
Logue, FC4
Dryburgh, FJ6
Cowan, RA5
Boyle, IT15
Kellihan, MJ1
Mangino, PD1
Weatherall, M1
Morton, AR4
Daley-Yates, PT1
Hoggarth, CR1
Waldburger, R1
Senn, HJ1
Christensen, JH1
Kristiansen, JH1
Seraj, F2
Murray, RM2
Ho, PW1
Santamaria, JD1
Pitt, P1
Potts, C1
Jerums, G1
Fitton, A1
McTavish, D1
Ritch, P1
Wiernik, PH1
Sarma, PR1
Richman, SP1
Tauer, K1
Neidhart, J1
Siegel, R1
Abbas, SK1
Varache, N1
Audran, M1
Clochon, P1
Bouachour, G1
Alquier, P1
Basle, MF1
Janisch, S1
Marosi, C1
Wogritsch, C1
Bosse, C1
Schratzberger, W1
Gerber, E1
Fortelny, A1
Lenzhofer, R1
Rainer, H1
Vega, EM1
Mautalen, CA1
Campbell, JH1
Ralston, S1
Banham, SW1
Tisell, LE2
Lindstedt, G2
Lundberg, PA2
Hurtado, J1
Esbrit, P1
Rapado, A1
O'Reilly, DS1
Beastall, GH1
Kwan, JT1
Cunningham, J3
Patel, U2
Judson, I1
Booth, F1
Gore, M1
McElwain, T1
Friefeld, J1
Halperin, F1
Rawlinson, PS1
Green, RH1
Coggins, AM1
Gibson, BE1
Hoekman, K1
Tjandra, YI1
Papapoulos, SE2
Wisneski, LA1
Campbell, J1
Warrell, RP3
Raymakers, JA2
Cantwell, BM3
Wingren, U1
Jacquet, AF5
Boudailliez, BR1
Pautard, BJ1
Sebert, JL1
Kremp, O1
Piussan, CX1
Devogelaer, JP1
Lambert, M1
Boland, B1
Godfraind, C1
Noel, H1
Nagant de Deuxchaisnes, C1
Allam, BF1
Boyce, BF1
Yap, AS1
Hockings, GI1
Fleming, SJ1
Khafagi, FA1
Hené, RJ1
Visser, WJ1
Duursma, SA1
de bos Kuil, RJ1
Dorhout Mees, EJ1
Jaeger, P5
Sawyer, N2
Newstead, C2
Drummond, A2
Canivet, JL1
Damas, P1
Lamy, M1
Kefford, R1
Stuart-Harris, R1
Newland, A1
McIntyre, HD1
Cameron, DP1
Urquhart, SM1
Davies, WE1
Magritte, A1
Sculier, JP2
Borkowski, A4
Perey, L1
von Fliedner, V1
Mannix, KA1
Carmichael, J1
Harris, AL3
Davis, JR1
Gardner, MD5
Jenkins, AS2
Cantwell, B1
Jodrell, DI1
Iveson, TJ1
Smith, IE1
van Holten-Verzantvoort, AT1
Cleton, FJ1
Hermans, J1
Kroon, HM1
Harinck, HI3
Vermey, P1
Elte, JW2
Neijt, JP2
McKillop, JH1
Alzaid, AA3
Cantrill, JA1
Craig, AE1
Anderson, DC1
Tan, TT1
Sutcliffe, N1
Thomson, JA1
Heaf, JG1
Hansen, M1
Rischin, D1
Bishop, JF1
Plantingh, AS1
Wildiers, J1
Glibert, F1
Nejai, S1
Yates, AJ1
Jerums, GJ1
Evans, RA1
Fraher, LJ1
Pot, M1
Klastersky, J1
Portmann, L1
Gibbs, CJ1
Peacock, M1
Fuss, M1
Karmali, R1
Gillet, C1
Corvilain, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420]Phase 14 participants (Actual)Interventional2005-12-31Completed
Bone Biopsy for Histomorphometry and Analysis of Bone Marrow Derived Osteoblast and Osteoclast Progenitors to Explore Mechanisms of Decreased Bone Mineral Density in Depression[NCT00001916]17 participants Observational1999-03-31Completed
Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation[NCT02074631]Phase 280 participants (Actual)Interventional2015-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

45 reviews available for pamidronate and Milk-Alkali Syndrome

ArticleYear
Hypercalcemia: A Review.
    JAMA, 2022, 10-25, Volume: 328, Issue:16

    Topics: Calcium; Coma; COVID-19; Dehydration; Denosumab; Humans; Hypercalcemia; Hyperparathyroidism, Primary

2022
Refractory Hypercalcemia in Squamous Cell Carcinoma of the Esophagus-a Case Report and Review of Literature.
    Journal of gastrointestinal cancer, 2019, Volume: 50, Issue:4

    Topics: Calcitonin; Calcium; Calcium-Regulating Hormones and Agents; Carcinoma, Squamous Cell; Cinacalcet; D

2019
Acute hypercalcemia and excessive bone resorption following anti-RANKL withdrawal: Case report and brief literature review.
    Bone, 2019, Volume: 120

    Topics: Acute Disease; Bone and Bones; Bone Resorption; Female; Humans; Hypercalcemia; Middle Aged; Pamidron

2019
Importance of dietary calcium and vitamin D in the treatment of hypercalcaemia in Williams-Beuren syndrome.
    Journal of pediatric endocrinology & metabolism : JPEM, 2014, Volume: 27, Issue:7-8

    Topics: Calcitriol; Calcium, Dietary; Child, Preschool; Diphosphonates; Female; Gene Deletion; Humans; Hyper

2014
Hypercalcemia in pediatric acute megakaryocytic leukemia: case report and review of the literature.
    Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Bone Diseases, Met

2009
Supportive therapy in multiple myeloma.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2011, Volume: 183

    Topics: Anemia; Blood Transfusion; Bone Diseases; Calcitonin; Clodronic Acid; Diphosphonates; Erythropoietin

2011
Modern management of malignant hypercalcemia.
    The American journal of hospice & palliative care, 2011, Volume: 28, Issue:7

    Topics: Bone Density Conservation Agents; Calcitonin; Clinical Protocols; Diphosphonates; Fluid Therapy; Gal

2011
The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy.
    The oncologist, 2002, Volume: 7, Issue:6

    Topics: Anti-Inflammatory Agents; Bone Resorption; Diphosphonates; Dose-Response Relationship, Drug; Humans;

2002
Efficacy of bisphosphonates in the management of skeletal complications of bone metastases and selection of clinical endpoints.
    American journal of clinical oncology, 2002, Volume: 25, Issue:6 Suppl 1

    Topics: Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Data Interpretation, Statistical; Diphosphonates;

2002
Treatment of hypercalcemia of malignancy with bisphosphonates.
    Seminars in oncology, 2002, Volume: 29, Issue:6 Suppl 21

    Topics: Bone Resorption; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; H

2002
Short-term, high-dose pamidronate-induced acute tubular necrosis: the postulated mechanisms of bisphosphonate nephrotoxicity.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:5

    Topics: Aged; Creatinine; Diphosphonates; Humans; Hypercalcemia; Kidney; Kidney Tubular Necrosis, Acute; Mal

2003
Hypercalcemia of malignancy.
    Seminars in nephrology, 2004, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Diphosphonates; Forecasting; Humans; Hypercalcemia; Imidazoles; Neoplasms; Pa

2004
Safety and convenience of a 15-minute infusion of zoledronic acid.
    The oncologist, 2004, Volume: 9, Issue:3

    Topics: Antineoplastic Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandr

2004
[Treatment of Paget's disease of bone: importance of the zoledronic acid].
    Arquivos brasileiros de endocrinologia e metabologia, 2006, Volume: 50, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Bone Resorption; Calcitonin; Dipho

2006
Progress in the treatment and palliation of advanced breast cancer: does the dose of pamidronate determine its effects?
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 7

    Topics: Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Diphosphonates; Female; Humans; Hypercal

1994
Update on the medical treatment of hypercalcemia of malignancy.
    Clinical pharmacy, 1993, Volume: 12, Issue:2

    Topics: Animals; Antineoplastic Agents; Calcitonin; Diphosphonates; Etidronic Acid; Gallium; Humans; Hyperca

1993
[Hypercalcemia as an emergency].
    Schweizerische medizinische Wochenschrift, 1993, Apr-17, Volume: 123, Issue:15

    Topics: Calcitonin; Calcium; Diphosphonates; Emergencies; Fluid Therapy; Furosemide; Humans; Hypercalcemia;

1993
Newer agents for the treatment of malignant hypercalcemia.
    The American journal of the medical sciences, 1993, Volume: 305, Issue:6

    Topics: Diphosphonates; Etidronic Acid; Gallium; Humans; Hypercalcemia; Neoplasms; Pamidronate

1993
Pathogenesis and management of cancer associated hypercalcaemia.
    Cancer surveys, 1994, Volume: 21

    Topics: Antineoplastic Agents; Calcitonin; Calcium; Clodronic Acid; Diphosphonates; Diuretics; Etidronic Aci

1994
Bone and cancer: pathophysiology and treatment of metastases.
    Bone, 1995, Volume: 17, Issue:2 Suppl

    Topics: Analgesics, Non-Narcotic; Bone and Bones; Bone Diseases, Metabolic; Bone Neoplasms; Breast Neoplasms

1995
[Bisphosphonates in the treatment concept of metastatic breast carcinoma].
    Geburtshilfe und Frauenheilkunde, 1996, Volume: 56, Issue:7

    Topics: Administration, Oral; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Female; Humans; Hypercalcemi

1996
Use of bisphosphonates in cancer patients.
    Cancer treatment reviews, 1996, Volume: 22, Issue:4

    Topics: Alendronate; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etid

1996
Pamidronate (Aredia, Ciba) in malignant hypercalcaemia.
    Intensive & critical care nursing, 1997, Volume: 13, Issue:1

    Topics: Diphosphonates; Drug Monitoring; Humans; Hypercalcemia; Neoplasms; Pamidronate

1997
Rationale for the use of bisphosphonates in breast cancer.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35 Suppl 5

    Topics: Bone Neoplasms; Bone Remodeling; Breast Neoplasms; Clodronic Acid; Cost-Benefit Analysis; Diphosphon

1996
[Paraneoplastic syndrome].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24 Suppl 3

    Topics: Alendronate; Anticoagulants; Cushing Syndrome; Diagnosis, Differential; Diphosphonates; Disseminated

1997
Pamidronate. A review of its use in the management of osteolytic bone metastases, tumour-induced hypercalcaemia and Paget's disease of bone.
    Drugs & aging, 1998, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Diphosphonates; Humans; Hypercalcemia; Neopl

1998
Bisphosphonates for treatment of childhood hypercalcemia.
    Pediatrics, 1998, Volume: 102, Issue:4 Pt 1

    Topics: Adolescent; Calcium; Child, Preschool; Diphosphonates; Female; Humans; Hypercalcemia; Immobilization

1998
Undifferentiated pancreatic cancer associated with humoral hypercalcemia of malignancy.
    Japanese journal of clinical oncology, 1998, Volume: 28, Issue:9

    Topics: Antineoplastic Agents; Carcinoma; Diphosphonates; Humans; Hypercalcemia; Liver Neoplasms; Male; Midd

1998
Current use of bisphosphonates in oncology. International Bone and Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:12

    Topics: Analgesics, Non-Narcotic; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clodron

1998
The role of bisphosphonates for the treatment of bone disease in multiple myeloma.
    Leukemia & lymphoma, 1998, Volume: 31, Issue:5-6

    Topics: Adult; Aged; Aged, 80 and over; Bone Remodeling; Clinical Trials as Topic; Clodronic Acid; Diphospho

1998
[Bisphosphonates and bone metastases].
    Bulletin du cancer, 1999, Volume: 86, Issue:9

    Topics: Antineoplastic Agents; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonat

1999
Bisphosphonates in multiple myeloma.
    Cancer, 2000, Jun-15, Volume: 88, Issue:12 Suppl

    Topics: Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Multiple Myeloma; Pain; Pamid

2000
Current and future directions in medical therapy: hypercalcemia.
    Cancer, 2000, Jun-15, Volume: 88, Issue:12 Suppl

    Topics: Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandronic Acid; Imidazoles; Neoplasms; Pamid

2000
Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Jan-15, Volume: 19, Issue:2

    Topics: Adult; Aged; Diphosphonates; Female; Humans; Hypercalcemia; Imidazoles; Male; Middle Aged; Neoplasms

2001
[Tumor-induced hypercalcemia. Review of bisphosphonate treatment].
    La Revue de medecine interne, 2001, Volume: 22, Issue:7

    Topics: Diagnosis, Differential; Diagnostic Errors; Diphosphonates; Etidronic Acid; Fluid Therapy; Hematolog

2001
Treatment of metastatic bone disease in breast cancer: bisphosphonates.
    Clinical breast cancer, 2000, Volume: 1, Issue:1

    Topics: Analgesics, Non-Narcotic; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; D

2000
Pamidronate.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:10

    Topics: Bone Neoplasms; Clinical Trials as Topic; Diphosphonates; Humans; Hypercalcemia; Osteitis Deformans;

1992
Bone metastases and tumor-induced hypercalcemia.
    Current opinion in oncology, 1992, Volume: 4, Issue:4

    Topics: Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Calcitonin; Combined Modality Therapy; Dipho

1992
Pamidronate. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease.
    Drugs, 1991, Volume: 41, Issue:2

    Topics: Animals; Bone Resorption; Diphosphonates; Drug Evaluation; Humans; Hypercalcemia; Osteitis Deformans

1991
Salmon calcitonin in the acute management of hypercalcemia.
    Calcified tissue international, 1990, Volume: 46 Suppl

    Topics: Adrenal Cortex Hormones; Calcitonin; Calcium; Diphosphonates; Gallium; Humans; Hypercalcemia; Pamidr

1990
Hypercalcemia and bone metastases in breast cancer.
    Current opinion in oncology, 1990, Volume: 2, Issue:6

    Topics: Alendronate; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Hyper

1990
[Hypercalcemia in the elderly].
    Tijdschrift voor gerontologie en geriatrie, 1990, Volume: 21, Issue:1

    Topics: Aged; Calcitonin; Calcium; Combined Modality Therapy; Diphosphonates; Female; Fluid Therapy; Homeost

1990
Disodium pamidronate, bisphosphonate for malignant hypercalcaemia.
    Irish medical journal, 1990, Volume: 83, Issue:1

    Topics: Diphosphonates; Drug Administration Schedule; Female; Humans; Hypercalcemia; Pamidronate

1990
1,25-Dihydroxyvitamin D-related hypercalcemia in lymphoma: two case reports.
    Clinical rheumatology, 1990, Volume: 9, Issue:3

    Topics: Aged; Calcitriol; Cataract; Diphosphonates; Female; Glucocorticoids; Humans; Hypercalcemia; Lymphoma

1990
[Biphosphonate as a therapeutic drug--experimental studies and clinical application].
    Therapeutische Umschau. Revue therapeutique, 1985, Volume: 42, Issue:6

    Topics: Animals; Calcinosis; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Hyperpar

1985

Trials

41 trials available for pamidronate and Milk-Alkali Syndrome

ArticleYear
Usefulness of pamidronate in severe secondary hyperparathyroidism in patients undergoing hemodialysis.
    Kidney international. Supplement, 2003, Issue:85

    Topics: Aged; Bone Density; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyroidism, Secondary; K

2003
Efficacy and safety of ibandronate in the treatment of hypercalcemia of malignancy: a randomized multicentric comparison to pamidronate.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2003, Volume: 11, Issue:8

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Bone Resorption; Diphosphonates; Female; Human

2003
Pamidronate reduces skeletal events but does not improve progression-free survival in early-stage untreated myeloma: results of a randomized trial.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

2003
Clodronate as a single-dose intravenous infusion effectively provides short-term correction of malignant hypercalcemia.
    Acta oncologica (Stockholm, Sweden), 2003, Volume: 42, Issue:7

    Topics: Calcium; Clodronic Acid; Diphosphonates; Double-Blind Method; Female; Humans; Hypercalcemia; Infusio

2003
Comparison of intravenous (3-amino-1-hydroxypropylidene)-1, 1-bisphosphonate and volume repletion in tumour-induced hypercalcaemia.
    Lancet (London, England), 1983, Jul-30, Volume: 2, Issue:8344

    Topics: Adult; Aged; Calcium; Diphosphonates; Female; Fluid Therapy; Follow-Up Studies; Glomerular Filtratio

1983
Comparative study of available medical therapy for hypercalcemia of malignancy.
    The American journal of medicine, 1983, Volume: 74, Issue:3

    Topics: Administration, Oral; Adult; Aged; Calcium; Clinical Trials as Topic; Diphosphonates; Etidronic Acid

1983
A randomised double-blind comparison of intravenous pamidronate and clodronate in the hypercalcaemia of malignancy.
    British journal of cancer, 1995, Volume: 72, Issue:5

    Topics: Bone Neoplasms; Bone Resorption; Clodronic Acid; Diphosphonates; Double-Blind Method; Humans; Hyperc

1995
Optimal frequency of administration of pamidronate in patients with hypercalcaemia of malignancy.
    Clinical endocrinology, 1994, Volume: 41, Issue:5

    Topics: Diphosphonates; Drug Administration Schedule; Female; Humans; Hypercalcemia; Pamidronate; Time Facto

1994
Response to intravenous bisphosphonate therapy in hypercalcaemic patients with and without bone metastases: the role of parathyroid hormone-related protein.
    British journal of cancer, 1994, Volume: 70, Issue:1

    Topics: Bone Neoplasms; Calcium; Diphosphonates; Humans; Hypercalcemia; Infusions, Intravenous; Kidney Tubul

1994
Treatment of cancer-associated hypercalcemia. Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone.
    Archives of internal medicine, 1994, Sep-12, Volume: 154, Issue:17

    Topics: Adult; Breast Neoplasms; Calcium; Diphosphonates; Double-Blind Method; Drug Administration Schedule;

1994
Significance of plasma PTH-rp in patients with hypercalcemia of malignancy treated with bisphosphonate.
    Cancer, 1994, Apr-15, Volume: 73, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle

1994
Single-dose intravenous therapy with pamidronate for the treatment of hypercalcemia of malignancy: comparison of 30-, 60-, and 90-mg dosages.
    The American journal of medicine, 1993, Volume: 95, Issue:3

    Topics: Aged; Diphosphonates; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hyperca

1993
Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group.
    The New England journal of medicine, 1996, Feb-22, Volume: 334, Issue:8

    Topics: Aged; Diphosphonates; Disease-Free Survival; Double-Blind Method; Female; Fractures, Bone; Humans; H

1996
Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group.
    The New England journal of medicine, 1996, Feb-22, Volume: 334, Issue:8

    Topics: Aged; Diphosphonates; Disease-Free Survival; Double-Blind Method; Female; Fractures, Bone; Humans; H

1996
Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group.
    The New England journal of medicine, 1996, Feb-22, Volume: 334, Issue:8

    Topics: Aged; Diphosphonates; Disease-Free Survival; Double-Blind Method; Female; Fractures, Bone; Humans; H

1996
Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group.
    The New England journal of medicine, 1996, Feb-22, Volume: 334, Issue:8

    Topics: Aged; Diphosphonates; Disease-Free Survival; Double-Blind Method; Female; Fractures, Bone; Humans; H

1996
Treatment of tumour-induced hypercalcaemia in advanced breast cancer patients with three different doses of disodium pamidronate adapted to the initial level of calcaemia.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1995, Volume: 3, Issue:6

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Calcium; Diphosphonates; Drug Monitoring; Female; Hum

1995
The role of bisphosphonates in the treatment of bone metastases--the U.S. experience.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1996, Volume: 4, Issue:3

    Topics: Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clinical Trials as Topic;

1996
[Bisphosphonates in the treatment concept of metastatic breast carcinoma].
    Geburtshilfe und Frauenheilkunde, 1996, Volume: 56, Issue:7

    Topics: Administration, Oral; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Female; Humans; Hypercalcemi

1996
Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group.
    The New England journal of medicine, 1996, Dec-12, Volume: 335, Issue:24

    Topics: Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Diphosphonates; Disease-Fr

1996
Pamidronate in the treatment of osteolytic bone metastases in breast cancer patients.
    British journal of clinical practice. Supplement, 1996, Volume: 87

    Topics: Bone Neoplasms; Bone Resorption; Breast Neoplasms; Diphosphonates; Female; Humans; Hypercalcemia; Pa

1996
Evaluation of new bone resorption markers in a randomized comparison of pamidronate or clodronate for hypercalcemia of malignancy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Biomarkers; Bone Neoplasms; Bone Resorption; Calcium; C

1997
Failure of oral pamidronate to reduce skeletal morbidity in multiple myeloma: a double-blind placebo-controlled trial. Danish-Swedish co-operative study group.
    British journal of haematology, 1998, Volume: 101, Issue:2

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols

1998
Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: a randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Disea

1999
Decreased efficacy of bisphosphonates for recurrences of tumor-induced hypercalcemia.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2000, Volume: 8, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents; Breast Neoplasms; Diphosphonates; Female; Humans; Hypercalcem

2000
Disodium pamidronate versus mithramycin in the management of tumour-associated hypercalcemia.
    Acta oncologica (Stockholm, Sweden), 1992, Volume: 31, Issue:8

    Topics: Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate; Plicamycin

1992
Pamidronate.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:10

    Topics: Bone Neoplasms; Clinical Trials as Topic; Diphosphonates; Humans; Hypercalcemia; Osteitis Deformans;

1992
Infusion rate and pharmacokinetics of intravenous pamidronate in the treatment of tumour-induced hypercalcaemia.
    Postgraduate medical journal, 1992, Volume: 68, Issue:800

    Topics: Adult; Aged; Aged, 80 and over; Diphosphonates; Drug Administration Schedule; Female; Humans; Hyperc

1992
Plicamycin and pamidronate in symptomatic tumor-related hypercalcemia: a prospective randomized crossover trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle Aged; Ne

1992
Comparative study of pamidronate disodium and etidronate disodium in the treatment of cancer-related hypercalcemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Calcium; Diphosphonates; Double-Blind Method; Etidronic Acid; Fem

1992
[Pamidronate in the treatment of tumor-associated hypercalcemia].
    Klinische Wochenschrift, 1991, Oct-02, Volume: 69, Issue:15

    Topics: Adult; Aged; Calcium; Diphosphonates; Female; Fluid Therapy; Humans; Hypercalcemia; Male; Middle Age

1991
Hypercalcemia and bone metastases in breast cancer.
    Current opinion in oncology, 1990, Volume: 2, Issue:6

    Topics: Alendronate; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Hyper

1990
[A new osteoclast inhibitor is useful in the treatment of severe hypercalcemia].
    Lakartidningen, 1990, Jul-25, Volume: 87, Issue:30-31

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Diphosphonates; Female; Humans; Hypercalcemia; Ma

1990
Fast (4-h) or slow (24-h) infusions of pamidronate disodium (aminohydroxypropylidene diphosphonate (APD)) as single shot treatment of hypercalcaemia.
    Bone and mineral, 1990, Volume: 9, Issue:2

    Topics: Calcium; Creatinine; Diphosphonates; Humans; Hypercalcemia; Kinetics; Neoplasms; Pamidronate

1990
Aminohydroxypropylidene bisphosphonate (APD) treatment for tumor-associated hypercalcemia: a randomized comparison between a 3-day treatment and single 24-hour infusions.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1989, Volume: 4, Issue:6

    Topics: Adult; Aged; Bone Resorption; Diphosphonates; Drug Administration Schedule; Female; Hematologic Test

1989
Comparison of different dose regimes of aminohydroxypropylidene-1,1-bisphosphonate (APD) in hypercalcaemia of malignancy.
    British journal of clinical pharmacology, 1989, Volume: 28, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Infusions, I

1989
Comparison of aminohydroxypropylidene diphosphonate, mithramycin, and corticosteroids/calcitonin in treatment of cancer-associated hypercalcaemia.
    Lancet (London, England), 1985, Oct-26, Volume: 2, Issue:8461

    Topics: Calcitonin; Calcium; Clinical Trials as Topic; Creatinine; Diphosphonates; Drug Therapy, Combination

1985
Reduced morbidity from skeletal metastases in breast cancer patients during long-term bisphosphonate (APD) treatment.
    Lancet (London, England), 1987, Oct-31, Volume: 2, Issue:8566

    Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Diphosph

1987
Effect of single high dose infusions of aminohydroxypropylidene diphosphonate on hypercalcaemia caused by cancer.
    British medical journal (Clinical research ed.), 1987, Feb-21, Volume: 294, Issue:6570

    Topics: Adult; Aged; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle Aged; Neoplasms; Pamidronat

1987
Single dose versus daily intravenous aminohydroxypropylidene biphosphonate (APD) for the hypercalcaemia of malignancy.
    British medical journal (Clinical research ed.), 1988, Mar-19, Volume: 296, Issue:6625

    Topics: Calcium; Diphosphonates; Drug Administration Schedule; Female; Humans; Hypercalcemia; Infusions, Int

1988
Treatment of hypercalcaemia of malignancy.
    British medical journal (Clinical research ed.), 1988, May-21, Volume: 296, Issue:6634

    Topics: Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate

1988
Questions about clinical trials in hypercalcemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:5

    Topics: Clinical Trials as Topic; Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate

1988
Role of bone and kidney in tumor-induced hypercalcemia and its treatment with bisphosphonate and sodium chloride.
    The American journal of medicine, 1987, Volume: 82, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bone Resorption; Calcium; Clinical Trials as Topic; Diphosphonates;

1987
[Treatment of neoplastic hypercalcemia using single-infusion diphosphonate].
    Schweizerische medizinische Wochenschrift, 1988, Jan-23, Volume: 118, Issue:3

    Topics: Adult; Aged; Bone Neoplasms; Calcium; Diphosphonates; Dose-Response Relationship, Drug; Female; Huma

1988

Other Studies

228 other studies available for pamidronate and Milk-Alkali Syndrome

ArticleYear
Highly potent geminal bisphosphonates. From pamidronate disodium (Aredia) to zoledronic acid (Zometa).
    Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17

    Topics: Animals; Bone Resorption; Calcitriol; Diphosphonates; Hypercalcemia; Imidazoles; In Vitro Techniques

2002
Isolated splenic sarcoidosis: a rare cause of hypercalcaemia in a patient with type 1 diabetes.
    BMJ case reports, 2021, Oct-13, Volume: 14, Issue:10

    Topics: Adult; Diabetes Mellitus, Type 1; Humans; Hypercalcemia; Male; Pamidronate; Sarcoidosis; Splenic Dis

2021
Severe neonatal hypercalcemia revealing congenital mesoblastic nephroma: A case report and management of neonatal hypercalcemia: Severe neonatal hypercalcemia revealing congenital mesoblastic nephroma.
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2022, Volume: 29, Issue:2

    Topics: Calcium; Female; Food, Fortified; Furosemide; Humans; Hypercalcemia; Hypertension; Infant Formula; I

2022
Pamidronate versus zoledronic acid for the treatment of multiple myeloma-related hypercalcemia.
    Kidney international, 2022, Volume: 101, Issue:5

    Topics: Diphosphonates; Humans; Hypercalcemia; Imidazoles; Multiple Myeloma; Pamidronate; Zoledronic Acid

2022
Use of Pamidronate for Hypercalcemia of Malignancy in Renal Dysfunction.
    Journal of pharmacy practice, 2021, Volume: 34, Issue:4

    Topics: Acute Kidney Injury; Diphosphonates; Humans; Hypercalcemia; Indiana; Neoplasms; Pamidronate; Retrosp

2021
Severe hypercalcaemia due to household cleaner ingestion.
    BMJ case reports, 2019, Oct-30, Volume: 12, Issue:10

    Topics: Acute Kidney Injury; Anti-Inflammatory Agents; Bone Density Conservation Agents; Eating; Household P

2019
Efficacy and Safety of Intravenous Pamidronate for Parathyroid Hormone-dependent Hypercalcemia in Hospitalized Patients.
    The Journal of clinical endocrinology and metabolism, 2021, 10-21, Volume: 106, Issue:11

    Topics: Administration, Intravenous; Aged; Bone Density Conservation Agents; Calcium; Case-Control Studies;

2021
Treatment of extreme hypercalcaemia: the role of haemodialysis.
    BMJ case reports, 2018, Jun-04, Volume: 2018

    Topics: Adenoma; Aged; Bone Density Conservation Agents; Calcitonin; Dexamethasone; Diphosphonates; Fluid Th

2018
Risks of the 'Sunshine pill' - a case of hypervitaminosis D.
    Clinical medicine (London, England), 2018, Volume: 18, Issue:4

    Topics: Aged; Bone Density Conservation Agents; Humans; Hypercalcemia; Male; Nutrition Disorders; Pamidronat

2018
Use of Pamidronate to Treat Hypercalcemia in an Oncology Dialysis Patient: A Case Report.
    The American journal of case reports, 2018, Sep-13, Volume: 19

    Topics: Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Female; Humans; Hypercalcemia; K

2018
Acute renal failure due to severe hypercalcemia and nephrocalcinosis treated with two doses of pamidronate in an infant with Williams-Beuren syndrome.
    The Turkish journal of pediatrics, 2018, Volume: 60, Issue:2

    Topics: Acute Kidney Injury; Bone Density Conservation Agents; Female; Humans; Hypercalcemia; In Situ Hybrid

2018
Comparison of Treatment Regimens in Management of Severe Hypercalcemia Due to Vitamin D Intoxication in Children
    Journal of clinical research in pediatric endocrinology, 2019, 05-28, Volume: 11, Issue:2

    Topics: Bone Density Conservation Agents; Female; Follow-Up Studies; Humans; Hypercalcemia; Infant; Male; Pa

2019
A case of severe, irreversible hypocalcemia after one dose of pamidronate administered for hypercalcemia of malignancy.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:7

    Topics: Bone Neoplasms; Calcium; Humans; Hypercalcemia; Hypocalcemia; Male; Middle Aged; Pamidronate; Risk F

2019
Primary isolated hepatosplenic sarcoidosis mimicking malignancy and causing symptomatic hypercalcaemia.
    BMJ case reports, 2019, Jan-22, Volume: 12, Issue:1

    Topics: Aftercare; Aged; Bone Density Conservation Agents; Diagnosis, Differential; Female; Humans; Hypercal

2019
Visual Diagnosis: An Infant with Rash and Hypercalcemia.
    Pediatrics in review, 2019, Volume: 40, Issue:3

    Topics: Exanthema; Fat Necrosis; Humans; Hypercalcemia; Hypothermia, Induced; Infant, Newborn; Male; Pamidro

2019
Bisphosphonates for treatment of severe idiopathic infantile hypercalcemia.
    Iranian journal of kidney diseases, 2013, Volume: 7, Issue:2

    Topics: Bone Density Conservation Agents; Calcium; Diphosphonates; Humans; Hypercalcemia; Male; Pamidronate;

2013
Intravenous pamidronate in the treatment of severe idiopathic infantile hypercalcemia.
    Iranian journal of kidney diseases, 2013, Volume: 7, Issue:2

    Topics: Biomarkers; Bone Density Conservation Agents; Calcium; Child, Preschool; Diagnosis, Differential; Di

2013
Approach to diagnosis and treatment of hypercalcemia in a patient with malignancy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:1

    Topics: Aged; Antineoplastic Agents; Bone and Bones; Bone Density Conservation Agents; Carcinoma, Squamous C

2014
Prolonged hypocalcaemia after pamidronate infusion in Riedel's thyroiditis associated hypoparathyroidism.
    The Netherlands journal of medicine, 2013, Volume: 71, Issue:8

    Topics: Bone Density Conservation Agents; Calcium Carbonate; Dihydrotachysterol; Diphosphonates; Female; Gas

2013
An infant with hypercalcemia: questions.
    Pediatric nephrology (Berlin, Germany), 2014, Volume: 29, Issue:11

    Topics: Bone Density Conservation Agents; Diagnosis, Differential; Diphosphonates; Humans; Hypercalcemia; In

2014
Exceptional localisation of an ectopic parathyroid adenoma at the level of the hyoid bone.
    BMJ case reports, 2014, Jun-11, Volume: 2014

    Topics: Adenoma; Bone Density Conservation Agents; Diphosphonates; Female; Humans; Hyoid Bone; Hypercalcemia

2014
Renal replacement therapy as a treatment for severe refractory hypercalcemia.
    Minerva endocrinologica, 2014, Volume: 39, Issue:3

    Topics: Adenoma; Adult; Carcinoma; Cinacalcet; Diphosphonates; Drug Resistance; Emergencies; Female; Furosem

2014
Pamidronate for long-term control of hypercalcemia associated with Williams syndrome.
    Indian pediatrics, 2015, Volume: 52, Issue:2

    Topics: Child, Preschool; Diphosphonates; Humans; Hypercalcemia; Male; Pamidronate; Williams Syndrome

2015
Quality and Outcomes of Treatment of Hypercalcemia of Malignancy.
    Cancer investigation, 2015, Volume: 33, Issue:8

    Topics: Aged; Bone Neoplasms; Calcitonin; Diphosphonates; Diuretics; Female; Glucocorticoids; Humans; Hyperc

2015
Case 4: How Much Is Too Much? A Case of Hypercalcemia in a 6-year-old Boy.
    Pediatrics in review, 2015, Volume: 36, Issue:9

    Topics: Bone Density Conservation Agents; Calcitonin; Child; Diagnosis, Differential; Dietary Supplements; D

2015
Just hypercalcaemia or acute ST elevation myocardial infarction? A review of hypercalcaemia-related electrocardiographic changes.
    BMJ case reports, 2015, Oct-21, Volume: 2015

    Topics: Aged; Bone Density Conservation Agents; Calcitonin; Calcium; Diphosphonates; Disease Management; Ele

2015
Severe hypercalcaemia in a child secondary to use of alternative therapies.
    BMJ case reports, 2016, Oct-06, Volume: 2016

    Topics: Autistic Disorder; Bone Density Conservation Agents; Calcium; Child, Preschool; Complementary Therap

2016
Effectiveness of pamidronate in severe neonatal hypercalcemia caused by subcutaneous fat necrosis: a case report.
    European journal of pediatrics, 2009, Volume: 168, Issue:5

    Topics: Anti-Inflammatory Agents; Child; Child, Preschool; Diphosphonates; Fat Necrosis; Female; Humans; Hyp

2009
Commentary on 'Pamidronate: treatment for severe hypercalcemia in neonatal subcutaneous fat necrosis' by Alos N. et al., Hormone Research 2006;65:289-294.
    Hormone research, 2008, Volume: 70, Issue:4

    Topics: Bone Density Conservation Agents; Calcium; Diphosphonates; Fat Necrosis; Female; Humans; Hypercalcem

2008
Reversal of hypercalcemic acute kidney injury by treatment with intravenous bisphosphonates.
    Pediatric nephrology (Berlin, Germany), 2009, Volume: 24, Issue:3

    Topics: Acute Disease; Adolescent; Bone Density Conservation Agents; Child; Child, Preschool; Diphosphonates

2009
Hypercalcemia and overexpression of CYP27B1 in a patient with nephrogenic systemic fibrosis: clinical vignette and literature review.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2009, Volume: 24, Issue:6

    Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Aged; Diphosphonates; Humans; Hypercalcemia; Leukemia, Lym

2009
Hypercalcemia associated with tertiary hyperparathyroidism managed conservatively with pamidronate in a hemodialysis patient.
    The American journal of the medical sciences, 2009, Volume: 337, Issue:4

    Topics: Aged; Calcium; Diphosphonates; Humans; Hypercalcemia; Hyperparathyroidism; Kidney Failure, Chronic;

2009
Hypercalcemia of immobilization.
    Journal of the American Medical Directors Association, 2009, Volume: 10, Issue:4

    Topics: Bone Density Conservation Agents; Diphosphonates; Diuretics; Fluid Therapy; Furosemide; Humans; Hype

2009
A case of resistant hypercalcemia of malignancy with a proposed treatment algorithm.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:9

    Topics: Aged; Algorithms; Bone Density Conservation Agents; Calcitonin; Carcinoma, Transitional Cell; Crysta

2009
[Paget's disease and hypercalcemia: coincidence or causal relationship?].
    Harefuah, 2009, Volume: 148, Issue:10

    Topics: Aged; Anti-Inflammatory Agents; Diphosphonates; Female; Fractures, Bone; Humans; Hypercalcemia; Oste

2009
[Efficient treatment of hypercalcaemia in neonatal subcutaneous fat necrosis].
    Ugeskrift for laeger, 2010, Jul-19, Volume: 172, Issue:29

    Topics: Asphyxia Neonatorum; Diphosphonates; Fat Necrosis; Female; Humans; Hypercalcemia; Infant, Newborn; I

2010
Nephrotic syndrome induced by pamidronate.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:4

    Topics: Adenocarcinoma; Aged; Bone Density Conservation Agents; Bone Neoplasms; Diphosphonates; Female; Huma

2011
Use of bisphosphonates to treat severe idiopathic hypercalcaemia in a young Ragdoll cat.
    Journal of feline medicine and surgery, 2011, Volume: 13, Issue:2

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Cat Diseases; Cats; Diphosphonates; Female;

2011
Severe hypercalcemia associated with uterine leiomyoma in pregnancy.
    Obstetrics and gynecology, 2011, Volume: 117, Issue:2 Pt 2

    Topics: Adult; Calcitriol; Calcium; Critical Care; Diphosphonates; Female; Gynecologic Surgical Procedures;

2011
Severe hypercalcemia associated with Williams syndrome successfully treated with pamidronate infusion therapy.
    Journal of pediatric endocrinology & metabolism : JPEM, 2011, Volume: 24, Issue:1-2

    Topics: Bone Density Conservation Agents; Diphosphonates; Female; Humans; Hypercalcemia; Infant; Infusion Pu

2011
Hyperparathyroidism due to eutopic PTH secretion from an ectopic intrathymic parathyroid cyst.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2011, Volume: 17, Issue:5

    Topics: Biomarkers; Biopsy; Calcitonin; Calcium; Choristoma; Diphosphonates; Diuretics; Female; Fluid Therap

2011
A case of myeloma with hypercalcemia caused by high serum concentrations of both parathyroid hormone-related peptide (PTHrP) and macrophage inflammatory protein-1α (MIP-1α).
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:24

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Calcitonin; Calciu

2011
Impact of chemotherapy on hypercalcemia in breast and lung cancer patients.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conserv

2012
Use of bisphosphonates in metastatic breast cancer: single institution review at the Dr. H. Bliss Murphy Cancer Centre.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013, Volume: 21, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Bone Diseases; Bone Neoplasms; Bre

2013
Megakaryoblastic transformation of polycythemia vera with hypercalcemia.
    Annals of hematology, 2002, Volume: 81, Issue:11

    Topics: Adrenocorticotropic Hormone; Bone Resorption; Busulfan; Calcium; Cell Transformation, Neoplastic; Di

2002
[Treatment of hypercalcemia of malignancy with pamidronate in a patient with advanced recurrent oral cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:13

    Topics: Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Consciousness Disorders; Diphosphonates; Dru

2002
Immobilization hypercalcemia in critical illness following bariatric surgery.
    Obesity surgery, 2002, Volume: 12, Issue:6

    Topics: Adult; Diphosphonates; Gastroplasty; Humans; Hypercalcemia; Immobilization; Male; Pamidronate; Parat

2002
Hypercalcemia due to sun exposure in a patient with multiple myeloma and elevated parathyroid hormone-related protein.
    European journal of endocrinology, 2003, Volume: 148, Issue:3

    Topics: Adult; Alkaline Phosphatase; Anti-Inflammatory Agents, Non-Steroidal; Diphosphonates; Humans; Hyperc

2003
Treatment of acute lymphoblastic leukemia-induced extreme hypercalcemia with pamidronate and calcitonin.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2003, Volume: 4, Issue:2

    Topics: Antineoplastic Agents; Calcitonin; Child; Diphosphonates; Female; Humans; Hypercalcemia; Pamidronate

2003
Pamidronate in a girl with chronic renal insufficiency dependent on parenteral nutrition.
    Pediatric nephrology (Berlin, Germany), 2003, Volume: 18, Issue:7

    Topics: Anti-Inflammatory Agents; Calcitonin; Child; Chlorothiazide; Colonic Diseases; Diphosphonates; Diure

2003
The use of subcutaneous pamidronate.
    Journal of pain and symptom management, 2003, Volume: 26, Issue:1

    Topics: Anti-Inflammatory Agents; Diphosphonates; Humans; Hypercalcemia; Injections, Subcutaneous; Pamidrona

2003
Isolated adrenocorticotropic hormone deficiency presenting with hypercalcemia in a patient on long-term hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:2

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Calcitriol; Corticotropin-Releasing Hormo

2003
Acute effect of pamidronate on PTH secretion in postmenopausal hemodialysis patients with secondary hyperparathyroidism.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:6

    Topics: Aged; Chronic Kidney Disease-Mineral and Bone Disorder; Diphosphonates; Female; Humans; Hypercalcemi

2003
Vitamin D intoxication and hypercalcaemia in an infant treated with pamidronate infusions.
    European journal of pediatrics, 2004, Volume: 163, Issue:3

    Topics: Anti-Inflammatory Agents; Diphosphonates; Humans; Hypercalcemia; Infant; Infusions, Intravenous; Mal

2004
Hypercalcemia in patients with disseminated coccidioidomycosis.
    The American journal of the medical sciences, 2004, Volume: 327, Issue:1

    Topics: Adult; Aged; Calcium; Coccidioidomycosis; Diphosphonates; Etidronic Acid; Female; Humans; Hypercalce

2004
A single bisphosphonate infusion is associated with improved functional capacity in elderly subjects with primary hyperparathyroidism.
    Aging clinical and experimental research, 2003, Volume: 15, Issue:6

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Antimetabolites; Bone and Bones; Bone Resorptio

2003
Zoledronate in a patient with pamidronate refractory hypercalcemia syndrome.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2004, Volume: 12, Issue:9

    Topics: Bone Resorption; Breast Neoplasms; Diphosphonates; Drug Resistance; Female; Humans; Hypercalcemia; I

2004
Neonatal severe hyperparathyroidism: genotype/phenotype correlation and the use of pamidronate as rescue therapy.
    European journal of pediatrics, 2004, Volume: 163, Issue:10

    Topics: Antineoplastic Agents; Dehydration; Diphosphonates; DNA Mutational Analysis; Female; Genotype; Human

2004
Pamidronate treatment for hypercalcemia in an infant receiving parenteral nutrition.
    Pharmacotherapy, 2004, Volume: 24, Issue:7

    Topics: Diphosphonates; Humans; Hypercalcemia; Infant, Newborn; Male; Pamidronate; Parenteral Nutrition

2004
Long-term control of hypercalcaemia in an infant with williams-Beuren syndrome after a single infusion of biphosphonate (Pamidronate).
    Acta paediatrica (Oslo, Norway : 1992), 2004, Volume: 93, Issue:7

    Topics: Anti-Inflammatory Agents; Calcium; Diphosphonates; Follow-Up Studies; Humans; Hypercalcemia; Infant;

2004
[Treatment of multiple myeloma with intravenous pamidronate. Pain prevention and suppression of hypercalcemia risk].
    Medicina, 2004, Volume: 64, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Diphosphonates; Female; Humans; Hypercalcemia; Injec

2004
Severe infantile hypercalcemia associated with Williams syndrome successfully treated with intravenously administered pamidronate.
    Pediatrics, 2004, Volume: 114, Issue:4

    Topics: Calcium, Dietary; Diphosphonates; Female; Humans; Hypercalcemia; Infant; Infusions, Intravenous; Mal

2004
Biochemical effects from treatment with bisphosphonate and surgery in patients with primary hyperparathyroidism.
    World journal of surgery, 2004, Volume: 28, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Diphosphonates; Female; Homeostasis; Human

2004
Hypercalcemia and childhood cancer: a 7-year experience.
    Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Diphosphonates; Female; Humans; Hypercal

2005
The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy.
    Endocrinology, 2005, Volume: 146, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bone Resorption; Calcium; Carrier Proteins; Cell Lin

2005
The issue of renal safety of zoledronic acid from a nephrologist's point of view.
    The oncologist, 2005, Volume: 10, Issue:5

    Topics: Antineoplastic Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandr

2005
"Safety and convenience of a 15-minute infusion of zoledronic acid": not so safe.
    The oncologist, 2005, Volume: 10, Issue:5

    Topics: Antineoplastic Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandr

2005
[Hypercalcemia and childhood cancer].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Diphosphonates; Female; Humans; Hypercal

2005
Ionized calcium in isolation may not detect all cases of symptomatic hypercalcaemia.
    Palliative medicine, 2005, Volume: 19, Issue:5

    Topics: Aged; Biomarkers; Bone Density Conservation Agents; Calcium; Diphosphonates; Female; Humans; Hyperca

2005
Chronic hypercalcemia as a reversible cause of cognitive impairment: improvement after a single administration of pamidronate.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:9

    Topics: Aged; Chronic Disease; Cognition Disorders; Diphosphonates; Female; Humans; Hypercalcemia; Hyperpara

2005
The use of pamidronate in a leukemic child with immobilization hypercalcemia.
    Leukemia research, 2006, Volume: 30, Issue:7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Diphos

2006
Osteonecrosis of the jaws and bisphosphonates. Report of three cases.
    Medicina oral, patologia oral y cirugia bucal, 2006, Jan-01, Volume: 11, Issue:1

    Topics: Aged; Bone Density Conservation Agents; Breast Neoplasms; Diphosphonates; Female; Humans; Hypercalce

2006
[Reversible posterior leucoencephalopathy due to hypercalcaemia].
    Nederlands tijdschrift voor geneeskunde, 2006, Mar-04, Volume: 150, Issue:9

    Topics: Antineoplastic Agents; Blindness, Cortical; Brain Diseases; Cognition Disorders; Diagnosis, Differen

2006
Pamidronate: Treatment for severe hypercalcemia in neonatal subcutaneous fat necrosis.
    Hormone research, 2006, Volume: 65, Issue:6

    Topics: Bone Density Conservation Agents; Calcium; Diphosphonates; Fat Necrosis; Female; Humans; Hypercalcem

2006
An unrecognized cause of recurrent hypercalcemia: immobilization.
    Southern medical journal, 2006, Volume: 99, Issue:4

    Topics: Aged; Bone Density Conservation Agents; Calcium; Diphosphonates; Exercise Therapy; Gout; Humans; Hyp

2006
Bisphosphonate-associated arthritis.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2006, Volume: 12, Issue:3

    Topics: Arthritis; Bone Density Conservation Agents; Breast Neoplasms; Diphosphonates; Fatal Outcome; Female

2006
[The incidence and management of bone metastasis from breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:8

    Topics: Bone and Bones; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Diphosphonates;

2006
Disodium pamidronate for treating severe hypercalcemia in a hemodialysis patient.
    Nature clinical practice. Nephrology, 2006, Volume: 2, Issue:8

    Topics: Antineoplastic Agents; Diphosphonates; Humans; Hypercalcemia; Kidney Failure, Chronic; Male; Middle

2006
Malignant hypercalcemia in pregnancy: effect of pamidronate on uterine contractions.
    Obstetrics and gynecology, 2006, Volume: 108, Issue:3 Pt 2

    Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Breech Presentation; Cesarean Sectio

2006
Hypercalcaemia in a patient with a gastrointestinal stromal tumour.
    Clinical endocrinology, 2007, Volume: 66, Issue:1

    Topics: Antineoplastic Agents; Benzamides; Bone Density Conservation Agents; Diphosphonates; Drug Therapy, C

2007
[Hypercalcaemia and malignant lymphoma. One case report].
    La Revue de medecine interne, 2007, Volume: 28, Issue:10

    Topics: Aged, 80 and over; Bone Density Conservation Agents; Calcitriol; Diphosphonates; Glucocorticoids; Hu

2007
Intracystic hemorrhage in a mediastinal cystic adenoma causing parathyrotoxic crisis.
    Head & neck, 2008, Volume: 30, Issue:1

    Topics: Adenoma; Adult; Bone Density Conservation Agents; Cystadenoma; Diphosphonates; Diuretics; Fluid Ther

2008
Tumor induced hypercalcemia in a patient with mediastinal synovial sarcoma.
    Journal of pediatric endocrinology & metabolism : JPEM, 2007, Volume: 20, Issue:7

    Topics: Adolescent; Bone Density Conservation Agents; Diphosphonates; Humans; Hypercalcemia; Male; Mediastin

2007
Pamidronate treatment of hypercalcemia caused by vitamin D toxicity.
    Journal of pediatric endocrinology & metabolism : JPEM, 2007, Volume: 20, Issue:11

    Topics: Bone Density Conservation Agents; Calcium; Diphosphonates; Drug Overdose; Humans; Hypercalcemia; Inf

2007
Hypercalcaemia due to malignancy. Role of the kidney and treatment.
    Contributions to nephrology, 1982, Volume: 33

    Topics: Calcitonin; Calcium; Diphosphonates; Extracellular Space; Fluid Therapy; Glomerular Filtration Rate;

1982
[Treatment of hypercalcemia in osteolytic metastases with oral amino-hydroxypropylidene-diphosphonate].
    Presse medicale (Paris, France : 1983), 1984, Feb-25, Volume: 13, Issue:8

    Topics: Administration, Oral; Adult; Aged; Bone Neoplasms; Bone Resorption; Calcium; Diphosphonates; Female;

1984
[Diphosphonates in the treatment of hypercalcemia].
    La Revue de medecine interne, 1984, Volume: 5, Issue:4

    Topics: Bone Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Hyperparathyr

1984
[Therapeutic possibilities in paraneoplastic hypercalcemia].
    Die Medizinische Welt, 1981, Aug-14, Volume: 32, Issue:32-33

    Topics: Adrenal Cortex Hormones; Adult; Aged; Calcitonin; Diphosphonates; Drug Therapy, Combination; Female;

1981
Efficacy of amino-hydroxypropylidene bisphosphonate in hypercalcemia: observations on regulation of serum calcium.
    Calcified tissue international, 1982, Volume: 34, Issue:4

    Topics: Adult; Aged; Bone Resorption; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyro

1982
Analysis of survival following treatment of tumour-induced hypercalcaemia with intravenous pamidronate (APD).
    British journal of cancer, 1995, Volume: 72, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle Aged; Ne

1995
Intravenous aminohydroxypropylidene bisphosphonate does not modify 99mTc-hydroxymethylene bisphosphonate bone scintigraphy. A prospective study.
    Revue du rhumatisme (English ed.), 1995, Volume: 62, Issue:2

    Topics: Aged; Bone Neoplasms; Diphosphonates; Female; Humans; Hypercalcemia; Infusions, Intravenous; Male; M

1995
Pamidronate treatment in patients with tumor-associated hypercalcemia: pharmacological effects and pharmacokinetics.
    Endocrine journal, 1994, Volume: 41, Issue:6

    Topics: Aged; Calcium; Diphosphonates; Female; Homeostasis; Humans; Hypercalcemia; Infusions, Intravenous; K

1994
Paraneoplastic endocrine syndromes.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Acromegaly; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Calcitonin; Cushing Syndr

1994
Intravenous pamidronate sodium therapy in immobilization-related hypercalcemia.
    Clinical nephrology, 1995, Volume: 43, Issue:2

    Topics: Acute Kidney Injury; Adult; Diphosphonates; Female; Humans; Hypercalcemia; Immobilization; Injection

1995
Hypercalcaemia in primary oxalosis: role of increased bone resorption and effects of treatment with pamidronate.
    Bone, 1995, Volume: 16, Issue:1

    Topics: Bone Resorption; Calcium Oxalate; Diphosphonates; Humans; Hypercalcemia; Immunohistochemistry; Kidne

1995
Alendronate distributed on bone surfaces inhibits osteoclastic bone resorption in vitro and in experimental hypercalcemia models.
    Bone, 1995, Volume: 16, Issue:2

    Topics: Alendronate; Animals; Autoradiography; Bone and Bones; Bone Resorption; Calcium; Carbon Radioisotope

1995
Effects of the antihypercalcemic drugs gallium nitrate and pamidronate on hormone release of pathologic human parathyroid cells.
    Surgery, 1995, Volume: 117, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Cytoplasm; Diphosphonates; Gallium; Humans; Hypercalcemia;

1995
Pamidronate for cancer-associated hypercalcemia.
    Archives of internal medicine, 1995, Mar-27, Volume: 155, Issue:6

    Topics: Diphosphonates; Drug Administration Schedule; Humans; Hypercalcemia; Neoplasms; Pamidronate

1995
Increased 1,25-(OH)2D2 concentration in a patient with malignancy-associated hypercalcemia receiving intravenous hyperalimentation inadvertently supplemented with vitamin D2.
    Internal medicine (Tokyo, Japan), 1993, Volume: 32, Issue:11

    Topics: Calcitriol; Contraindications; Diphosphonates; Ergocalciferols; Humans; Hypercalcemia; Male; Middle

1993
Effects of treatment of malignancy-associated hypercalcemia on serum parathyroid hormone-related protein.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:4

    Topics: Alendronate; Calcitriol; Calcium; Creatinine; Diphosphonates; Female; Humans; Hypercalcemia; Male; N

1994
Treatment of tumour-induced hypercalcaemia with the bisphosphonate pamidronate: dose-response relationship and influence of tumour type.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Calcium; Diphosphonates; Dose-Response Relationship,

1994
[Disodium pamidronate (APD) in therapy of hypercalcemia in primary hyperparathyroidism].
    Wiener klinische Wochenschrift, 1994, Volume: 106, Issue:13

    Topics: Aged; Aged, 80 and over; Calcium; Diphosphonates; Dose-Response Relationship, Drug; Female; Humans;

1994
Parathyroid hormone-related protein and response to pamidronate in tumour-induced hypercalcaemia.
    Lancet (London, England), 1993, Jun-26, Volume: 341, Issue:8861

    Topics: Bone Neoplasms; Calcium; Cyclic AMP; Diphosphonates; Electrolytes; Humans; Hypercalcemia; Kidney Tub

1993
Treatment of hypercalcaemia with pamidronate in patients with end stage renal failure.
    Scandinavian journal of urology and nephrology, 1993, Volume: 27, Issue:4

    Topics: Calcium Carbonate; Diphosphonates; Female; Humans; Hydroxycholecalciferols; Hypercalcemia; Kidney Fa

1993
Parathyroid hormone-related protein and life expectancy in hypercalcemic cancer patients.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Diphosphonates; Female; Humans; Hypercalcemia

1994
Prolonged remission of hypercalcaemia due to parathyroid carcinoma with pamidronate.
    Postgraduate medical journal, 1994, Volume: 70, Issue:821

    Topics: Calcium; Carcinoma; Diphosphonates; Female; Humans; Hypercalcemia; Middle Aged; Pamidronate; Parathy

1994
Evaluation and treatment of hypercalcemia.
    Hospital practice (Office ed.), 1994, Jun-15, Volume: 29, Issue:6

    Topics: Adenoma; Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Diagnosis, Differential; Diphosphonates; Fe

1994
Effect of aminohydroxypropylidene diphosphonate on the bone metabolism of patients with parathyroid adenoma.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1993, Volume: 25, Issue:9

    Topics: Adenoma; Adult; Alkaline Phosphatase; Bone and Bones; Calcitriol; Calcium; Creatinine; Diphosphonate

1993
Inhibition of 1,25(OH)2D production by hypercalcemia in osteitis fibrosa cystica: influence on parathyroid hormone secretion and hungry bone disease.
    Bone and mineral, 1993, Volume: 23, Issue:1

    Topics: Adenoma; Alkaline Phosphatase; Bone Resorption; Calcitonin; Calcitriol; Calcium; Calcium Carbonate;

1993
[Results of using Aredia for hypercalcemia in oncology patients].
    Terapevticheskii arkhiv, 1993, Volume: 65, Issue:9

    Topics: Bone Neoplasms; Breast Neoplasms; Calcium; Diphosphonates; Drug Evaluation; Female; Humans; Hypercal

1993
Severe immobilization-induced hypercalcemia in a child after liver transplantation successfully treated with pamidronate.
    Transplantation, 1994, Volume: 57, Issue:2

    Topics: Alkaline Phosphatase; Calcium; Child; Diphosphonates; Humans; Hypercalcemia; Immobilization; Infusio

1994
Circulating PTHrP concentrations in tumor-induced hypercalcemia: influence on the response to bisphosphonate and changes after therapy.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:6

    Topics: Adult; Aged; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle Aged; Neoplasms; P

1993
Long-term follow up of breast cancer patients treated for hypercalcaemia with aminohydroxypropylidene bisphosphate (APD).
    Breast cancer research and treatment, 1993, Volume: 25, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Calcium; Diphosphonates; Female; Follow-Up Studies; Humans; Hypercalc

1993
Parathyroid hormone-related protein (PTHrP) does not regulate 1,25-dihydroxyvitamin D serum levels in hypercalcemia of malignancy.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:3

    Topics: Adult; Aged; Dihydroxycholecalciferols; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle

1993
A case of squamous cell lung carcinoma with high concentration of parathyroid hormone-related peptide in serum and pleural effusion presenting hypercalcemia.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:4

    Topics: Blotting, Northern; Carcinoma, Squamous Cell; Chromatography, Gel; Diagnosis, Differential; Diphosph

1993
Elevated cytokine levels in a patient with AIDS and hypercalcemia: effects of therapy with pamidronate.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Cachexia; Cytokines; Diphosphonates; Humans; Hypercalcemi

1995
Vitamin D intoxication causes hypercalcaemia by increased bone resorption which responds to pamidronate.
    Clinical endocrinology, 1995, Volume: 43, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Bone Resorption; Calcium; Diphosphonates; Female; Humans; Hydroxycho

1995
Intravenous pamidronate for hypercalcemia of primary hyperparathyroidism.
    Southern medical journal, 1996, Volume: 89, Issue:6

    Topics: Aged; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyroidism; Infusions, Intrav

1996
Milk-alkali syndrome induced by 1,25(OH)2D in a patient with hypoparathyroidism.
    Journal of the National Medical Association, 1996, Volume: 88, Issue:5

    Topics: Aged; Anti-Inflammatory Agents; Calcitriol; Calcium Carbonate; Diphosphonates; Emergencies; Female;

1996
An audit of the management of malignant hypercalcaemia.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1996, Volume: 8, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Clinical Protocols; Diphosphonates; Female; Follow-Up Studi

1996
Safety of pamidronate in patients with renal failure and hypercalcemia.
    Clinical nephrology, 1996, Volume: 45, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Creatinine; Diphosphonates; Female; Follow-Up Studies; Huma

1996
Iritis following intravenous pamidronate.
    Australian and New Zealand journal of medicine, 1996, Volume: 26, Issue:3

    Topics: Aged; Diphosphonates; Female; Humans; Hypercalcemia; Iritis; Male; Middle Aged; Osteitis Deformans;

1996
Role of bisphosphonates in prevention and treatment of bone metastases from breast cancer.
    The Canadian journal of oncology, 1995, Volume: 5 Suppl 1

    Topics: Analgesics, Non-Narcotic; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; D

1995
Symptomatic hypocalcemia after intravenous pamidronate.
    Journal of palliative care, 1996,Spring, Volume: 12, Issue:1

    Topics: Aged; Alberta; Carcinoma, Transitional Cell; Diphosphonates; Female; Humans; Hypercalcemia; Hypocalc

1996
Malignant hypercalcaemia in pregnancy and antenatal administration of intravenous pamidronate.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1996, Volume: 8, Issue:4

    Topics: Adult; Breast Neoplasms; Diphosphonates; Fatal Outcome; Female; Humans; Hypercalcemia; Infant, Newbo

1996
Effects of bisphosphonate (pamidronate) on bone resorption resulting from metastasis of a squamous cell carcinoma: report of an autopsy case and evaluation of bone resorbing activity in an experimental animal model.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1996, Volume: 54, Issue:11

    Topics: Acid Phosphatase; Aged; Animals; Bone Neoplasms; Bone Resorption; Carcinoma, Squamous Cell; Diphosph

1996
[Effect of pamidronate and interferon-alpha on bone and lung metastases and hypercalcemia in a patient with renal cell carcinoma].
    Hinyokika kiyo. Acta urologica Japonica, 1996, Volume: 42, Issue:11

    Topics: Antineoplastic Agents; Bone Neoplasms; Carcinoma, Renal Cell; Diphosphonates; Humans; Hypercalcemia;

1996
Pamidronate (Aredia) and zoledronate: update on clinical results. Introduction.
    British journal of clinical practice. Supplement, 1996, Volume: 87

    Topics: Bone Neoplasms; Diphosphonates; Humans; Hypercalcemia; Imidazoles; Organophosphorus Compounds; Osteo

1996
Pamidronate (Aredia).
    British journal of clinical practice. Supplement, 1996, Volume: 87

    Topics: Bone Resorption; Diphosphonates; Humans; Hypercalcemia; Osteoclasts; Pamidronate

1996
Pamidronate in the treatment of bone metastases--the European experience.
    British journal of clinical practice. Supplement, 1996, Volume: 87

    Topics: Bone Neoplasms; Bone Resorption; Clinical Trials as Topic; Diphosphonates; Europe; Humans; Hypercalc

1996
Zoledronate: the preclinical pharmacology.
    British journal of clinical practice. Supplement, 1996, Volume: 87

    Topics: Animals; Bone Resorption; Cholecalciferol; Depression, Chemical; Diphosphonates; Disease Models, Ani

1996
Hypercalcaemia in osteogenesis imperfecta treated with pamidronate.
    Archives of disease in childhood, 1997, Volume: 76, Issue:2

    Topics: Adolescent; Diphosphonates; Fractures, Spontaneous; Humans; Hypercalcemia; Male; Osteogenesis Imperf

1997
Acute pseudogout as a complication of pamidronate.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:4

    Topics: Aged; Chondrocalcinosis; Diphosphonates; Female; Humans; Hypercalcemia; Pamidronate

1997
Treatment of immobilisation hypercalcaemia in acute intermittent porphyria: experience from three cases.
    Journal of neurology, neurosurgery, and psychiatry, 1997, Volume: 62, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Diphosphonates; Female; Humans; Hypercalcemia; Pamidronate; Porphy

1997
Long-term management of hypercalcaemia in chronically active sarcoidosis.
    Journal of the Royal Society of Medicine, 1997, Volume: 90, Issue:3

    Topics: Adult; Chronic Disease; Diphosphonates; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Hy

1997
Childhood cancer and hypercalcemia: report of a case treated with pamidronate.
    The Journal of pediatrics, 1997, Volume: 130, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Calcitonin; Child, Preschool; Diphosphonates; Glucoc

1997
Hypercalcemia in an AIDS patient treated with growth hormone.
    AIDS (London, England), 1997, Volume: 11, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Calcium; Diphosphonates; Growth Hormone; HIV Wasting Synd

1997
Use of pamidronate in the management of acute cancer-related hypercalcemia in children.
    Medical and pediatric oncology, 1998, Volume: 30, Issue:2

    Topics: Acute Disease; Adolescent; Calcium; Child; Child, Preschool; Diphosphonates; Female; Humans; Hyperca

1998
Immobilization hypercalcemia in incomplete paraplegia: successful treatment with pamidronate.
    Archives of physical medicine and rehabilitation, 1998, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Diphosphonates; Humans; Hypercalcemia; Male; Pamidronate; Paraplegia

1998
[Bone metastases: pathogenesis and treatment with diphosphonates].
    Bulletin et memoires de l'Academie royale de medecine de Belgique, 1997, Volume: 152, Issue:3

    Topics: Antineoplastic Agents; Bone Neoplasms; Diphosphonates; Humans; Hypercalcemia; Neoplasm Proteins; Ost

1997
Rapid skeletal turnover and hypercalcemia associated with markedly elevated interleukin-6 levels in a young black man.
    Bone, 1998, Volume: 22, Issue:3

    Topics: Adult; Alendronate; Alkaline Phosphatase; Black People; Bone and Bones; Bone Remodeling; Collagen; C

1998
Use of pamidronate in the management of acute cancer-related hypercalcemia in children.
    Medical and pediatric oncology, 1998, Volume: 31, Issue:1

    Topics: Antineoplastic Agents; Child; Diphosphonates; Humans; Hypercalcemia; Hypocalcemia; Hypophosphatemia;

1998
Disseminated coccidioidomycosis associated with hypercalcemia.
    Mayo Clinic proceedings, 1998, Volume: 73, Issue:9

    Topics: Adult; Antifungal Agents; Bone and Bones; Coccidioidomycosis; Diphosphonates; Humans; Hypercalcemia;

1998
Effect of combination treatment with a vitamin D analog (OCT) and a bisphosphonate (AHPrBP) in a nude mouse model of cancer-associated hypercalcemia.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:9

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cachexia; Calcitriol

1998
Accumulation of bisphosphonates in human artery and their effects on human and rat arterial function in vitro.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:3

    Topics: Animals; Arteries; Calcium Channel Blockers; Clodronic Acid; Diphosphonates; Drug Synergism; Etidron

1998
Hypercalcemia in malignant paraganglioma due to parathyroid hormone-related protein.
    Hormone research, 1998, Volume: 50, Issue:4

    Topics: Adolescent; Diphosphonates; Humans; Hypercalcemia; Male; Pamidronate; Paraganglioma; Parathyroid Hor

1998
The use of pamidronate for hypercalcemia secondary to acute vitamin D intoxication.
    Journal of toxicology. Clinical toxicology, 1998, Volume: 36, Issue:7

    Topics: Aged; Diphosphonates; Drug Overdose; Female; Humans; Hypercalcemia; Iatrogenic Disease; Pamidronate;

1998
The use of pamidronate in three children with renal disease.
    Pediatric nephrology (Berlin, Germany), 1998, Volume: 12, Issue:9

    Topics: Adolescent; Anti-Inflammatory Agents; Bone Density; Bone Diseases, Metabolic; Child; Diphosphonates;

1998
Severe prolonged hypocalcaemia following pamidronate for malignant hypercalcaemia.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1998, Volume: 10, Issue:6

    Topics: Adenocarcinoma; Adenoma; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols

1998
Bisphosphonates for metastatic bone pain.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1999, Volume: 7, Issue:1

    Topics: Analgesics, Non-Narcotic; Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Breast Neoplasms;

1999
Use of disodium pamidronate in children with hypercalcemia awaiting liver transplantation.
    Pediatric transplantation, 1998, Volume: 2, Issue:2

    Topics: Child; Child, Preschool; Diphosphonates; Drug Administration Schedule; Female; Humans; Hypercalcemia

1998
Hypercalcemia in an euthyroid patient with secondary hypoadrenalism and diabetes insipidus due to hypothalamic tumor.
    Endocrine journal, 1998, Volume: 45, Issue:6

    Topics: Acute Kidney Injury; Adrenal Insufficiency; Adult; Antineoplastic Agents; Diabetes Insipidus; Diphos

1998
Brief report: Medulloblastoma with widespread skeletal metastases presenting with hypercalcemia.
    Medical and pediatric oncology, 1999, Volume: 33, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Cerebellar Neoplasms; Diphosphonates; Female; Hum

1999
[A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Di

1999
Metabolic disturbances after a single dose of 30 mg pamidronate for leukaemia-associated hypercalcaemia in a 11-year-old boy.
    European journal of pediatrics, 1999, Volume: 158, Issue:9

    Topics: Antineoplastic Agents; Calcium; Child; Diphosphonates; Humans; Hypercalcemia; Hypocalcemia; Leukemia

1999
Immobilization hypercalcemia treatment with pamidronate disodium after spinal cord injury.
    Archives of physical medicine and rehabilitation, 1999, Volume: 80, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Calcium; Diphosphonates; Dose-Response R

1999
Use of pamidronate to reverse vitamin D3-induced toxicosis in dogs.
    American journal of veterinary research, 1999, Volume: 60, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Blood Chemical Analysis; Calcitonin; Cholecalciferol;

1999
Use of bisphosphonates in hypercalcemia associated with childhood cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:6

    Topics: Antineoplastic Agents; Child; Diphosphonates; Dose-Response Relationship, Drug; Humans; Hypercalcemi

1999
[Two cases of malignancy-associated hypercalcemia from bone metastases of breast cancer successfully treated with combination therapy using pamidronate and calcitonin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:5

    Topics: Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Calcitonin; Consciousness Disorders; Diphos

2000
Effects of fasting, feeding, and bisphosphonate administration on serum calcitriol levels in phosphate-deprived rats.
    Kidney international, 2000, Volume: 58, Issue:3

    Topics: Animals; Antineoplastic Agents; Calcitriol; Calcium; Diphosphonates; Eating; Fasting; Hypercalcemia;

2000
[Immobilization hypercalcemia as a complication of polyneuropathy].
    Der Nervenarzt, 2000, Volume: 71, Issue:8

    Topics: Anti-Inflammatory Agents; Calcium; Diphosphonates; Humans; Hypercalcemia; Immobilization; Male; Midd

2000
Overdosage of pamidronate in a patient with renal cell carcinoma.
    Medical oncology (Northwood, London, England), 2000, Volume: 17, Issue:4

    Topics: Aged; Anti-Inflammatory Agents; Carcinoma, Renal Cell; Diphosphonates; Female; Humans; Hypercalcemia

2000
Optimising treatment of bone metastases by Aredia(TM) and Zometa(TM).
    Breast cancer (Tokyo, Japan), 2000, Volume: 7, Issue:4

    Topics: Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Female; Humans; Hypercalcem

2000
Positive effect of radiotherapy and surgery on hormonally active pulmonary metastases of primary parathyroid carcinoma.
    European journal of endocrinology, 2000, Volume: 143, Issue:6

    Topics: Antineoplastic Agents; Calcium; Combined Modality Therapy; Diphosphonates; Female; Follow-Up Studies

2000
Tumor 'flare' hypercalcemia--an additional indication for bisphosphonates?
    Oncology, 2001, Volume: 60, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Bone Neoplasms; Breast Neoplasm

2001
Intravenous bisphosphonate for hypercalcemia accompanying subcutaneous fat necrosis: a novel treatment approach.
    Clinical pediatrics, 2001, Volume: 40, Issue:4

    Topics: Diphosphonates; Fat Necrosis; Humans; Hypercalcemia; Infant; Infusions, Intravenous; Male; Pamidrona

2001
Hypercalcemia in patients with oral squamous cell carcinoma.
    Clinical oral investigations, 2001, Volume: 5, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Calcitonin; Carcinoma, Squamous Cell; Diphosphona

2001
Bones, groans and blasts.
    Journal of paediatrics and child health, 2001, Volume: 37, Issue:5

    Topics: Adolescent; Antineoplastic Agents; Diagnosis, Differential; Diphosphonates; Female; Humans; Hypercal

2001
Effect of pamidronate in a rat hypercalcemia model induced by cholecalciferol.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:4

    Topics: Animals; Body Weight; Calcitonin; Calcium; Cholecalciferol; Diphosphonates; Female; Hypercalcemia; P

1992
Factors predicting the acute effect of pamidronate on serum calcium in hypercalcemia of malignancy.
    Calcified tissue international, 1992, Volume: 51, Issue:6

    Topics: Absorption; Calcium; Cyclic AMP; Diphosphonates; Humans; Hypercalcemia; Infusions, Intravenous; Kidn

1992
Pamidronate use in two cases of hypercalcaemia secondary to hyperparathyroidism.
    The New Zealand medical journal, 1992, Sep-23, Volume: 105, Issue:942

    Topics: Aged; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyroidism; Pamidronate

1992
Treatment of resistant tumor-induced hypercalcemia with escalating doses of pamidronate (APD).
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:8

    Topics: Bone Resorption; Diphosphonates; Drug Resistance; Female; Humans; Hypercalcemia; Middle Aged; Neopla

1992
[Combination therapy with pamidronate and calcitonin in hypercalcemic crisis caused by primary hyperparathyroidism].
    Ugeskrift for laeger, 1992, Nov-16, Volume: 154, Issue:47

    Topics: Aged; Calcitonin; Diphosphonates; Drug Therapy, Combination; Female; Humans; Hypercalcemia; Hyperpar

1992
Recovery of parathyroid hormone secretion during correction of tumor-associated hypercalcemia.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:6

    Topics: Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle Aged; Neoplasms; Pamidronate; P

1992
Circulating PTH and PTHrP levels before and after treatment of tumor induced hypercalcemia with Pamidronate Disodium (APD).
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:6

    Topics: Calcium; Diphosphonates; Humans; Hypercalcemia; Neoplasm Proteins; Neoplasms; Pamidronate; Parathyro

1992
Pamidronate.
    The Medical letter on drugs and therapeutics, 1992, Jan-10, Volume: 34, Issue:861

    Topics: Clinical Trials as Topic; Diphosphonates; Humans; Hypercalcemia; Hyperparathyroidism; Neoplasms; Ost

1992
A comparison of low versus high dose pamidronate in cancer-associated hypercalcaemia.
    Bone and mineral, 1991, Volume: 15, Issue:3

    Topics: Calcium; Creatinine; Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate

1991
Parathyroid hormone-related protein(50-69) and response to pamidronate therapy for tumour-induced hypercalcaemia.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Female; Humans; Hy

1991
Aminohydroxypropylidene bisphosphonate (AHPrBP) treatment of severe immobilization hypercalcaemia in a young patient.
    Clinical rheumatology, 1991, Volume: 10, Issue:3

    Topics: Adolescent; Biopsy; Calcium; Diphosphonates; Humans; Hypercalcemia; Ilium; Immobilization; Male; Ost

1991
Intravenous pamidronic acid in hypercalcemia due to parathyroid carcinoma.
    Medicina, 1991, Volume: 51, Issue:2

    Topics: Adult; Diphosphonates; Female; Humans; Hypercalcemia; Infusions, Intravenous; Male; Middle Aged; Pam

1991
Symptomatic hypercalcaemia in lung cancer.
    Respiratory medicine, 1991, Volume: 85, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcitonin; Diphosphonates; Drug Therapy, Combination; Female; Human

1991
Bisphosphonate treatment of bone metastases and hypercalcemia of malignancy.
    Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:8

    Topics: Animals; Bone and Bones; Bone Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hyp

1991
Disodium pamidronate in the preoperative treatment of hypercalcemia in patients with primary hyperparathyroidism.
    Surgery, 1991, Volume: 110, Issue:3

    Topics: Adolescent; Aged; Aged, 80 and over; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyroid

1991
Relative role of bone and kidney in the hypercalcaemia associated with the rat Walker carcinosarcoma 256.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:1

    Topics: Amifostine; Animals; Bone and Bones; Calcium; Carcinoma 256, Walker; Diphosphonates; Female; Hyperca

1991
Direct and indirect assessment of the parathyroid hormone response to pamidronate therapy in Paget's disease of bone and hypercalcaemia of malignancy.
    Bone and mineral, 1991, Volume: 12, Issue:2

    Topics: Aged; Calcium; Cyclic AMP; Diphosphonates; Female; Glomerular Filtration Rate; Humans; Hypercalcemia

1991
Comment on "Use of aminohydroxypropylidene bisphosphonate (AHPrBP, "APD") for the treatment of hypercalcemia in patients with renal impairment" by Yap et al.
    Clinical nephrology, 1991, Volume: 35, Issue:4

    Topics: Diphosphonates; Humans; Hypercalcemia; Pamidronate; Renal Dialysis

1991
Use of bisphosphonates in hypercalcaemia due to malignancy.
    Lancet (London, England), 1990, Mar-24, Volume: 335, Issue:8691

    Topics: Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate

1990
Chronic high-dose pamidronate in refractory malignant hypercalcaemia.
    Lancet (London, England), 1990, Mar-31, Volume: 335, Issue:8692

    Topics: Diphosphonates; Drug Tolerance; Humans; Hypercalcemia; Male; Middle Aged; Multiple Myeloma; Pamidron

1990
Dose of bisphosphonate for hypercalcaemia of malignancy.
    Lancet (London, England), 1990, Jun-16, Volume: 335, Issue:8703

    Topics: Aged; Carcinoma, Renal Cell; Diphosphonates; Female; Humans; Hypercalcemia; Infusions, Intravenous;

1990
Malignant osteopetrosis: hypercalcaemia after bone marrow transplantation.
    Archives of disease in childhood, 1991, Volume: 66, Issue:5

    Topics: Bone Marrow Transplantation; Calcitonin; Child, Preschool; Diphosphonates; Female; Humans; Hypercalc

1991
The role of 1,25-dihydroxyvitamin D in the maintenance of hypercalcemia in a patient with an ovarian carcinoma producing parathyroid hormone-related protein.
    Cancer, 1991, Aug-01, Volume: 68, Issue:3

    Topics: Aged; Bone Resorption; Calcitriol; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Ovarian N

1991
Cancer-associated hypercalcemia: morbidity and mortality. Clinical experience in 126 treated patients.
    Annals of internal medicine, 1990, Apr-01, Volume: 112, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Calcitonin; Diphosphonates; Dru

1990
Fast and effective treatment of malignant hypercalcemia. Combination of suppositories of calcitonin and a single infusion of 3-amino 1-hydroxypropylidene-1-bisphosphonate.
    Archives of internal medicine, 1990, Volume: 150, Issue:10

    Topics: Aged; Calcitonin; Diphosphonates; Drug Therapy, Combination; Female; Fluid Therapy; Humans; Hypercal

1990
Leukaemia-associated hypercalcaemia in a 10-year-old boy: effectiveness of aminohydroxypropylidene biphosphonate.
    Pediatric nephrology (Berlin, Germany), 1990, Volume: 4, Issue:5

    Topics: Calcium; Child; Diphosphonates; Humans; Hypercalcemia; Leukemia; Male; Pamidronate

1990
Immobilization-related hypercalcaemia--a possible novel mechanism and response to pamidronate.
    Postgraduate medical journal, 1990, Volume: 66, Issue:781

    Topics: Adult; Calcium; Creatinine; Diphosphonates; Female; Humans; Hypercalcemia; Immobilization; Male; Mid

1990
Use of aminohydroxypropylidene bisphosphonate (AHPrBP, "APD") for the treatment of hypercalcemia in patients with renal impairment.
    Clinical nephrology, 1990, Volume: 34, Issue:5

    Topics: Acute Kidney Injury; Adult; Diphosphonates; Female; Humans; Hypercalcemia; Kidney Failure, Chronic;

1990
No effect of APD (amino hydroxypropylidene bisphosphonate) on hypercalcemia in patients with renal osteodystrophy.
    Bone, 1990, Volume: 11, Issue:1

    Topics: Adult; Chronic Kidney Disease-Mineral and Bone Disorder; Diphosphonates; Female; Humans; Hypercalcem

1990
Response to retreatment of malignant hypercalcemia with the bisphosphonate AHPrBP (APD): respective role of kidney and bone.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1990, Volume: 5, Issue:3

    Topics: Bone and Bones; Breast Neoplasms; Calcium; Carcinoma, Squamous Cell; Diphosphonates; Female; Humans;

1990
Posttraumatic parathyroid crisis and severe hypercalcemia treated with intravenous bisphosphonate (APD). Case report.
    Acta anaesthesiologica Belgica, 1990, Volume: 41, Issue:1

    Topics: Abdominal Injuries; Acute Disease; Brain Concussion; Diphosphonates; Female; Humans; Hypercalcemia;

1990
Renal phosphate threshold and response to pamidronate in humoral hypercalcaemia of malignancy.
    Lancet (London, England), 1989, Jul-29, Volume: 2, Issue:8657

    Topics: Bone Neoplasms; Diphosphonates; Humans; Hypercalcemia; Infusions, Intravenous; Kidney; Neoplasms; Pa

1989
Pamidronate and hypercalcaemia of malignancy.
    Lancet (London, England), 1989, Sep-09, Volume: 2, Issue:8663

    Topics: Breast Neoplasms; Combined Modality Therapy; Diphosphonates; Drug Evaluation; Female; Humans; Hyperc

1989
One-shot high-dose pamidronate disodium (APD): effective, simple treatment for hypercalcaemia in haematological malignancy.
    Clinical and laboratory haematology, 1989, Volume: 11, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Diphosphonates; Drug Administration Schedule;

1989
Immobilization hypercalcaemia responding to intravenous pamidronate sodium therapy.
    Postgraduate medical journal, 1989, Volume: 65, Issue:762

    Topics: Adolescent; Diphosphonates; Humans; Hypercalcemia; Immobilization; Infusions, Intravenous; Male; Pam

1989
Treatment of tumor-induced osteolysis by APD.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1989, Volume: 116

    Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Dose-Response Rela

1989
Single high-dose (45 mg) infusions of aminohydroxypropylidene diphosphonate for severe malignant hypercalcemia.
    Cancer, 1989, Sep-15, Volume: 64, Issue:6

    Topics: Adult; Aged; Diphosphonates; Female; Follow-Up Studies; Humans; Hypercalcemia; Hypocalcemia; Infusio

1989
Single high dose aminohydroxypropylidene diphosphonate infusions to treat cancer-associated hypercalcaemia.
    Lancet (London, England), 1986, Jan-18, Volume: 1, Issue:8473

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Calcium; Diphosphonates; Female; Humans; Hypercalcemi

1986
Symptomatic hypocalcaemia after treatment with high-dose aminohydroxypropylidene diphosphonate.
    Lancet (London, England), 1987, Mar-14, Volume: 1, Issue:8533

    Topics: Diphosphonates; Female; Humans; Hypercalcemia; Hypocalcemia; Middle Aged; Pamidronate

1987
Treatment of severe hypercalcaemia with mithramycin and aminohydroxypropylidene bisphosphonate.
    Lancet (London, England), 1988, Jul-30, Volume: 2, Issue:8605

    Topics: Diphosphonates; Drug Therapy, Combination; Humans; Hypercalcemia; Pamidronate; Plicamycin

1988
Malignancy-associated hypercalcaemia: relationship between mechanisms of hypercalcaemia and response to antihypercalcaemic therapy.
    Bone and mineral, 1987, Volume: 2, Issue:3

    Topics: Calcitonin; Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate; Plicamycin

1987
New inhibitors of osteolysis: implications for hypercalcemia and bone metastases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:8

    Topics: Amifostine; Bone Neoplasms; Bone Resorption; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia;

1986
Treatment of malignancy-associated hypercalcemia with intravenous aminohydroxypropylidene diphosphonate.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:8

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Calcium; Cyclic AMP; Diphosphonates; Female; Head and

1986
Treatment of cancer associated hypercalcaemia with combined aminohydroxypropylidene diphosphonate and calcitonin.
    British medical journal (Clinical research ed.), 1986, Jun-14, Volume: 292, Issue:6535

    Topics: Bone Resorption; Calcitonin; Calcium; Creatinine; Diphosphonates; Drug Therapy, Combination; Humans;

1986
Dose-dependent effect of AHPrBP in malignant hypercalcemia: wishful thinking and facts.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:10

    Topics: Diphosphonates; Dose-Response Relationship, Drug; Humans; Hypercalcemia; Neoplasms; Pamidronate

1988
Treatment of hypercalcaemia in thyrotoxicosis with aminohydroxypropylidene diphosphonate.
    Postgraduate medical journal, 1988, Volume: 64, Issue:749

    Topics: Adult; Diphosphonates; Female; Humans; Hypercalcemia; Infusions, Intravenous; Male; Pamidronate; Thy

1988
Treatment of refractory cancer-associated hypercalcemia with aminohydroxypropylidene diphosphonate.
    Acta medica Scandinavica, 1988, Volume: 224, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Diphosphonates; Female; Humans; Hypercalcemia; Lung Neoplasms

1988
Treatment of hypercalcemia of malignancy with intermittent single infusions of 3-amino-1-hydroxypropylidene-1, 1-biphosphonate (APD)
    Australian and New Zealand journal of medicine, 1988, Volume: 18, Issue:5

    Topics: Breast Neoplasms; Diphosphonates; Drug Administration Schedule; Female; Humans; Hypercalcemia; Middl

1988
Clinical experience with aminohydroxypropylidene bisphosphonate (APD) in the management of cancer-associated hypercalcaemia.
    The Quarterly journal of medicine, 1988, Volume: 68, Issue:258

    Topics: Diphosphonates; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hype

1988
Dose-response in the treatment of hypercalcemia of malignancy by a single infusion of the bisphosphonate AHPrBP.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Creatinine; Diphosphonates; Dose-Response Relationship, Dru

1988
[Bone metastases and hypercalcemia in cancer].
    Revue medicale de Liege, 1988, Mar-15, Volume: 43, Issue:6

    Topics: Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Female; Humans; Hypercalcem

1988
A comparison of single and multiple intravenous infusions of 3-amino-1-hydroxypropylidene-1, 1-bisphosphonate (APD) in the treatment of hypercalcemia of malignancy.
    Australian and New Zealand journal of medicine, 1987, Volume: 17, Issue:4

    Topics: Bone Neoplasms; Calcium; Diphosphonates; Drug Administration Schedule; Female; Humans; Hypercalcemia

1987
Aminohydroxypropylidene diphosphonate treatment of hypercalcemic crisis due to primary hyperparathyroidism.
    Australian and New Zealand journal of medicine, 1987, Volume: 17, Issue:1

    Topics: Adult; Diphosphonates; Humans; Hypercalcemia; Hyperparathyroidism; Male; Pamidronate

1987
A single-day treatment of tumor-induced hypercalcemia by intravenous amino-hydroxypropylidene bisphosphonate.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1986, Volume: 1, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Infusions, I

1986
Effects of decreasing serum calcium on circulating parathyroid hormone and vitamin D metabolites in normocalcaemic and hypercalcaemic patients treated with APD.
    Bone and mineral, 1986, Volume: 1, Issue:1

    Topics: Calcium; Diphosphonates; Humans; Hypercalcemia; Osteitis Deformans; Pamidronate; Parathyroid Hormone

1986
Dose/response study of aminohydroxypropylidene bisphosphonate in tumor-associated hypercalcemia.
    The American journal of medicine, 1987, Volume: 82, Issue:5

    Topics: Adult; Aged; Diphosphonates; Dose-Response Relationship, Drug; Female; Humans; Hypercalcemia; Male;

1987
3(Amino-1,1-hydroxypropylidene) bisphosphonate (APD) for hypercalcaemia of breast cancer.
    British journal of cancer, 1987, Volume: 56, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Calcium; Diphosphonates; Female; Fluid Therapy; Humans; Hydroxyprolin

1987
Oral versus intravenous AHPrBP (APD) in the treatment of hypercalcemia of malignancy.
    Bone, 1986, Volume: 7, Issue:4

    Topics: Administration, Oral; Aged; Diphosphonates; Female; Humans; Hypercalcemia; Infusions, Parenteral; Ma

1986
Hypercalcaemia due to sarcoidosis corrects with bisphosphonate treatment.
    Postgraduate medical journal, 1986, Volume: 62, Issue:732

    Topics: Calcium; Diphosphonates; Humans; Hypercalcemia; Male; Middle Aged; Pamidronate; Retrospective Studie

1986
[Treatment of hypercalcemia].
    Revue medicale de Bruxelles, 1986, Volume: 7, Issue:1

    Topics: Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate

1986