pamidronate has been researched along with Melanoma in 4 studies
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the protective effect of apigenin against growth inhibition of normal epithelial human prostatic (PNT2), transgenic adenocarcinoma of mouse prostate (TRAMP-C1) and metastatic melanoma cells (B16F10) in combined treatments with bisphosphonates and ionizing radiation (IR)." | 3.79 | Effects of bisphosphonates in combination with ionizing radiation and antioxidants on the growth of prostate and melanoma cells lines. ( Achel, DG; Alcaraz, M; Alcaraz-Saura, M; Olivares, A, 2013) |
| "Cutaneous melanoma is one of the highly malignant human tumours, due to its tendency to generate early metastases and its resistance to classical chemotherapy." | 1.32 | Nitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells. ( Forsea, AM; Geilen, CC; Müller, C; Orfanos, CE; Riebeling, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alcaraz, M | 1 |
| Olivares, A | 1 |
| Achel, DG | 1 |
| Alcaraz-Saura, M | 1 |
| Riebeling, C | 2 |
| Forsea, AM | 2 |
| Raisova, M | 1 |
| Orfanos, CE | 2 |
| Geilen, CC | 3 |
| Müller, C | 1 |
| Oppermann, M | 1 |
| Fecker, LF | 1 |
| Gillissen, B | 1 |
| Daniel, PT | 1 |
| Eberle, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420] | Phase 1 | 4 participants (Actual) | Interventional | 2005-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for pamidronate and Melanoma
| Article | Year |
|---|---|
Effects of bisphosphonates in combination with ionizing radiation and antioxidants on the growth of prostate and melanoma cells lines.
Topics: Animals; Antioxidants; Apigenin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modal | 2013 |
The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Division; Diphosphonates; Diterpenes; En | 2002 |
Nitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells.
Topics: Antimetabolites; Antineoplastic Agents; Cell Cycle; Clodronic Acid; Diphosphonates; Disease Progress | 2004 |
Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk / Bik.
Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; A | 2005 |