Page last updated: 2024-11-02

pamidronate and Lung Neoplasms

pamidronate has been researched along with Lung Neoplasms in 34 studies

Lung Neoplasms: Tumors or cancer of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"Intravenous injection of 4 mg zoledronic acid can significantly reduce bone pain and bone resorption marker in urine in the Chinese patients with bone metastasis from solid tumor or multiple myeloma, which is tolerable and also comparable to pamidronate in the efficacy and safety."9.13[Phase III clinical study of zoledronic acid in the treatment of pain induced by bone metastasis from solid tumor or multiple myeloma]. ( Chen, Q; Dong, M; Feng, FY; Feng, JF; Jiao, SC; Li, J; Liu, JW; Ren, J; Song, ST; Wang, XW; Wang, YJ; Wang, ZH; Xie, GR; Xu, N; Zhang, Y; Zhou, QH, 2008)
"Clinical studies showed that pamidronate has curative effects on pain induced by bone metastasis."9.11[Pamidronate in treatment of pain caused by bone metastasis]. ( Cai, Y; Chen, YL; Liu, HQ; Liu, MZ; Ren, J; Wang, DJ; Zhan, QY, 2004)
"We assessed the effects of 60-mg single doses of pamidronate disodium compared with saline alone in the treatment of cancer-associated hypercalcemia."9.07Treatment of cancer-associated hypercalcemia. Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone. ( Ahmann, F; Chapman, R; Gill, I; Gucalp, R; Heffernan, M; Knight, RD; Madajewicz, S; Navari, R; Theriault, R; Zelenakas, K, 1994)
" He was treated with seven courses of combined chemotherapy (CDDP + etoposide), until he showed extreme hypercalcemia and acute renal failure."7.70[A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate]. ( Kametani, T; Koshida, H; Masuda, S, 1999)
"Pamidronate is a second generation bisphosphonate used for treating tumor-induced hypercalcemia and for preventing the development of new bone metastasis."7.69[Effect of pamidronate and interferon-alpha on bone and lung metastases and hypercalcemia in a patient with renal cell carcinoma]. ( Arima, K; Hioki, T; Kawamura, J; Kise, H; Kobayashi, K; Sugiura, Y; Tochigi, H; Yanagawa, M, 1996)
"Treatment with pamidronate, an inhibitor of osteoclastic bone resorption, given every 2 weeks by i."5.31Pamidronate-induced remission of pain associated with hypertrophic pulmonary osteoarthropathy in chemoendocrine therapy-refractory inoperable metastatic breast carcinoma. ( Naito, Y; Sakurai, T; Suzuma, T; Tamaki, T; Umemura, T; Yoshimasu, T; Yoshimura, G, 2001)
"Intravenous injection of 4 mg zoledronic acid can significantly reduce bone pain and bone resorption marker in urine in the Chinese patients with bone metastasis from solid tumor or multiple myeloma, which is tolerable and also comparable to pamidronate in the efficacy and safety."5.13[Phase III clinical study of zoledronic acid in the treatment of pain induced by bone metastasis from solid tumor or multiple myeloma]. ( Chen, Q; Dong, M; Feng, FY; Feng, JF; Jiao, SC; Li, J; Liu, JW; Ren, J; Song, ST; Wang, XW; Wang, YJ; Wang, ZH; Xie, GR; Xu, N; Zhang, Y; Zhou, QH, 2008)
"Clinical studies showed that pamidronate has curative effects on pain induced by bone metastasis."5.11[Pamidronate in treatment of pain caused by bone metastasis]. ( Cai, Y; Chen, YL; Liu, HQ; Liu, MZ; Ren, J; Wang, DJ; Zhan, QY, 2004)
"We assessed the effects of 60-mg single doses of pamidronate disodium compared with saline alone in the treatment of cancer-associated hypercalcemia."5.07Treatment of cancer-associated hypercalcemia. Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone. ( Ahmann, F; Chapman, R; Gill, I; Gucalp, R; Heffernan, M; Knight, RD; Madajewicz, S; Navari, R; Theriault, R; Zelenakas, K, 1994)
"Zoledronic acid (Zometa is a third-generation nitrogen-containing parenteral bisphosphonate indicated for the treatment of bone metastases due to solid tumours or multiple myeloma and for hypercalcaemia of malignancy (HCM)."4.84Zoledronic acid: a pharmacoeconomic review of its use in the management of bone metastases. ( McKeage, K; Plosker, GL, 2008)
" Followed by hydration with saline, pamidronate is effective for the control of symptomatic hypercalcemia."4.79[Paraneoplastic syndrome]. ( Hara, N; Nakanishi, Y; Takayama, K, 1997)
" He was treated with seven courses of combined chemotherapy (CDDP + etoposide), until he showed extreme hypercalcemia and acute renal failure."3.70[A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate]. ( Kametani, T; Koshida, H; Masuda, S, 1999)
"Pamidronate is a second generation bisphosphonate used for treating tumor-induced hypercalcemia and for preventing the development of new bone metastasis."3.69[Effect of pamidronate and interferon-alpha on bone and lung metastases and hypercalcemia in a patient with renal cell carcinoma]. ( Arima, K; Hioki, T; Kawamura, J; Kise, H; Kobayashi, K; Sugiura, Y; Tochigi, H; Yanagawa, M, 1996)
"Hypercalcemia is mainly caused by bone resorption due to either secretion of cytokines including parathyroid hormone-related protein (PTHrP) or bone metastases."1.38Impact of chemotherapy on hypercalcemia in breast and lung cancer patients. ( Hassali, MA; Hassan, BA; Othman, SB; Weiderpass, E; Yusoff, ZB, 2012)
"Pamidronate was well tolerated and only grade 1 or 2 toxicities were registered."1.35Routine use of pamidronate in NSCLC patients with bone metastasis: results from a retrospective analysis. ( Mitterer, M; Seeber, A; Spizzo, G, 2009)
"We report a renal cell carcinoma case in which multiple lung and bone metastases displayed remarkable remission to BP therapy using 30 mg pamidronate once, 4 mg zoledronate once, and weekly 10 mg incadronate 10 times for 3 months."1.35Lung and bone metastases from renal cell carcinoma responsive to bisphosphonates: a case report. ( Fujii, Y; Fukui, I; Kijima, T; Okubo, Y; Suyama, T; Yonese, J, 2008)
"We report on a patient with parathyroid carcinoma with hypercalcaemia and pulmonary metastases, treated with pamidronate and radiotherapy and later with surgery."1.31Positive effect of radiotherapy and surgery on hormonally active pulmonary metastases of primary parathyroid carcinoma. ( Boquist, L; Kristoffersson, A; Rasmuson, T, 2000)
"Treatment with pamidronate, an inhibitor of osteoclastic bone resorption, given every 2 weeks by i."1.31Pamidronate-induced remission of pain associated with hypertrophic pulmonary osteoarthropathy in chemoendocrine therapy-refractory inoperable metastatic breast carcinoma. ( Naito, Y; Sakurai, T; Suzuma, T; Tamaki, T; Umemura, T; Yoshimasu, T; Yoshimura, G, 2001)
"Pamidronate appears to be an effective therapy for HPOA."1.30The use of pamidronate in hypertrophic pulmonary osteoarthropathy (HPOA). ( Francis, H; Nicklason, F; Speden, D; Ward, J, 1997)
"A 57-year-old man with lung squamous cell carcinoma revealed hypercalcemia, hypophosphoremia, elevation of nephrogenous cAMP and metabolic alkalosis."1.29A case of squamous cell lung carcinoma with high concentration of parathyroid hormone-related peptide in serum and pleural effusion presenting hypercalcemia. ( Haji, M; Hara, N; Ichinose, Y; Iguchi, H; Katakami, H; Nawata, H; Nishi, Y; Ohta, M; Tanaka, S, 1993)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19903 (8.82)18.7374
1990's12 (35.29)18.2507
2000's14 (41.18)29.6817
2010's5 (14.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oster, G1
Lamerato, L1
Glass, AG1
Richert-Boe, KE1
Lopez, A1
Chung, K1
Richhariya, A1
Dodge, T1
Wolff, GG1
Balakumaran, A1
Edelsberg, J1
Huang, CY1
Wang, L1
Feng, CJ1
Yu, P1
Cai, XH1
Yao, WX1
Xu, Y1
Liu, XK1
Zhu, WJ1
Wang, Y1
Zhou, J1
Lu, Y1
Wang, YS1
Dong, M1
Feng, FY1
Zhang, Y1
Xie, GR1
Wang, YJ1
Liu, JW1
Song, ST1
Zhou, QH1
Ren, J2
Jiao, SC1
Li, J1
Wang, XW1
Chen, Q1
Wang, ZH1
Xu, N1
Feng, JF1
Crawford, BS1
McNulty, RM1
Kraut, EH1
Turowski, RC1
Spizzo, G1
Seeber, A1
Mitterer, M1
Heras, P1
Hatzopoulos, A1
Heras, V1
Kritikos, N1
Karagiannis, S1
Kritikos, K1
Hassan, BA1
Yusoff, ZB1
Hassali, MA1
Othman, SB1
Weiderpass, E1
Rai, Y1
Sagara, Y2
Takahama, T1
Ando, M1
Wang, DJ1
Liu, HQ1
Chen, YL1
Zhan, QY1
Cai, Y1
Liu, MZ1
Saba, N1
Khuri, F1
Andritzky, B1
Schuch, G1
Thoem, I1
Goern, M1
Brandl, S1
Bokemeyer, C1
Laack, E1
McKeage, K1
Plosker, GL1
Kijima, T1
Fujii, Y1
Suyama, T1
Okubo, Y1
Yonese, J1
Fukui, I1
Gucalp, R1
Theriault, R1
Gill, I1
Madajewicz, S1
Chapman, R1
Navari, R1
Ahmann, F1
Zelenakas, K1
Heffernan, M1
Knight, RD1
Mundy, GR1
Iguchi, H2
Katakami, H1
Ichinose, Y1
Nishi, Y1
Tanaka, S1
Hara, N2
Ohta, M1
Haji, M1
Nawata, H1
Kise, H1
Kobayashi, K1
Arima, K1
Yanagawa, M1
Tochigi, H1
Kawamura, J1
Hioki, T1
Sugiura, Y1
Speden, D1
Nicklason, F1
Francis, H1
Ward, J1
Nakanishi, Y1
Takayama, K1
Vainas, IG1
Tsilikas, C1
Grecu, A1
Pasaitu, K1
Stergiou, I1
Kortsaris, AH1
Endo, K1
Katsumata, K1
Kubodera, N1
Teramoto, T1
Ikeda, K1
Fujita, T1
Ogata, E1
Koshida, H1
Kametani, T1
Masuda, S1
Jin, M1
Yang, B1
Lei, L1
Oura, S1
Yoshimasu, T2
Sakurai, T2
Nakamura, T1
Kokawa, Y1
Matsuyama, K1
Ohta, F1
Naito, Y2
Rasmuson, T1
Kristoffersson, A1
Boquist, L1
Bileckot, R1
Touazi, S1
Auvinet, B1
Le Lain, JC1
Rudlowski, C1
Rath, W1
Becker, AJ1
Wiestler, OD1
Buttner, R1
Suzuma, T1
Yoshimura, G1
Umemura, T1
Tamaki, T1
Dodwell, DJ1
Abbas, SK1
Morton, AR1
Howell, A1
Campbell, JH1
Ralston, S1
Boyle, IT1
Banham, SW1
Mann, K1
Body, JJ1
Borkowski, A1
Cleeren, A1
Bijvoet, OL1
Heaf, JG1
Hansen, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420]Phase 14 participants (Actual)Interventional2005-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for pamidronate and Lung Neoplasms

ArticleYear
The role of bisphosphonates in the management of advanced cancer with a focus on non-small-cell lung cancer. Part 1: Mechanisms of action, role of biomarkers and preclinical applications.
    Oncology, 2005, Volume: 68, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung;

2005
Zoledronic acid: a pharmacoeconomic review of its use in the management of bone metastases.
    PharmacoEconomics, 2008, Volume: 26, Issue:3

    Topics: Administration, Oral; Bone Density Conservation Agents; Bone Neoplasms; Bone Resorption; Breast Neop

2008
[Paraneoplastic syndrome].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24 Suppl 3

    Topics: Alendronate; Anticoagulants; Cushing Syndrome; Diagnosis, Differential; Diphosphonates; Disseminated

1997
Metastatic parathyroid carcinoma (mPCa): natural history and treatment of a case.
    Journal of experimental & clinical cancer research : CR, 1997, Volume: 16, Issue:4

    Topics: Antineoplastic Agents; Calcitonin; Carcinoma; Diagnosis, Differential; Diphosphonates; Humans; Lung

1997

Trials

4 trials available for pamidronate and Lung Neoplasms

ArticleYear
[Phase III clinical study of zoledronic acid in the treatment of pain induced by bone metastasis from solid tumor or multiple myeloma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2008, Volume: 30, Issue:3

    Topics: Adult; Aged; Analgesics; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Collage

2008
A comparative study of intravenous ibandronate and pamindronate in patients with bone metastases from breast or lung cancer: effect on metastatic bone pain.
    American journal of therapeutics, 2011, Volume: 18, Issue:5

    Topics: Bone Density Conservation Agents; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Diphosphonates;

2011
[Pamidronate in treatment of pain caused by bone metastasis].
    Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:11 Suppl

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Dose-Response Relationship, Drug; Fem

2004
Treatment of cancer-associated hypercalcemia. Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone.
    Archives of internal medicine, 1994, Sep-12, Volume: 154, Issue:17

    Topics: Adult; Breast Neoplasms; Calcium; Diphosphonates; Double-Blind Method; Drug Administration Schedule;

1994

Other Studies

26 other studies available for pamidronate and Lung Neoplasms

ArticleYear
You're the Flight Surgeon.
    Aerospace medicine and human performance, 2017, May-01, Volume: 88, Issue:5

    Topics: Adenocarcinoma; Adult; Bone Density Conservation Agents; Chemotherapy, Adjuvant; Diphosphonates; Hum

2017
Use of intravenous bisphosphonates in patients with breast, lung, or prostate cancer and metastases to bone: a 15-year study in two large US health systems.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2014, Volume: 22, Issue:5

    Topics: Aged; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Female; Hu

2014
Bisphosphonates enhance EGFR-TKIs efficacy in advanced NSCLC patients with EGFR activating mutation: A retrospective study.
    Oncotarget, 2016, Oct-11, Volume: 7, Issue:41

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carc

2016
Extended use of intravenous bisphosphonate therapy for the prevention of skeletal complications in patients with cancer.
    Cancer investigation, 2009, Volume: 27, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms;

2009
Routine use of pamidronate in NSCLC patients with bone metastasis: results from a retrospective analysis.
    Anticancer research, 2009, Volume: 29, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Ad

2009
Impact of chemotherapy on hypercalcemia in breast and lung cancer patients.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conserv

2012
[Effective weekly paclitaxel therapy for massive metastatic breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:5

    Topics: Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; D

2004
Long-term survival after second-line therapy with docetaxel and carboplatin and monthly pamidronic acid in a woman with metastatic non-small cell lung cancer.
    Onkologie, 2006, Volume: 29, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung;

2006
Lung and bone metastases from renal cell carcinoma responsive to bisphosphonates: a case report.
    International journal of urology : official journal of the Japanese Urological Association, 2008, Volume: 15, Issue:6

    Topics: Bone Density Conservation Agents; Bone Neoplasms; Carcinoma, Renal Cell; Diphosphonates; Humans; Imi

2008
Evaluation and treatment of hypercalcemia.
    Hospital practice (Office ed.), 1994, Jun-15, Volume: 29, Issue:6

    Topics: Adenoma; Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Diagnosis, Differential; Diphosphonates; Fe

1994
A case of squamous cell lung carcinoma with high concentration of parathyroid hormone-related peptide in serum and pleural effusion presenting hypercalcemia.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:4

    Topics: Blotting, Northern; Carcinoma, Squamous Cell; Chromatography, Gel; Diagnosis, Differential; Diphosph

1993
[Effect of pamidronate and interferon-alpha on bone and lung metastases and hypercalcemia in a patient with renal cell carcinoma].
    Hinyokika kiyo. Acta urologica Japonica, 1996, Volume: 42, Issue:11

    Topics: Antineoplastic Agents; Bone Neoplasms; Carcinoma, Renal Cell; Diphosphonates; Humans; Hypercalcemia;

1996
The use of pamidronate in hypertrophic pulmonary osteoarthropathy (HPOA).
    Australian and New Zealand journal of medicine, 1997, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Aged; Carcinoma, Non-Small-Cell Lung; Diphosphonates; Fatal Outcome; Female; Humans;

1997
Effect of combination treatment with a vitamin D analog (OCT) and a bisphosphonate (AHPrBP) in a nude mouse model of cancer-associated hypercalcemia.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:9

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cachexia; Calcitriol

1998
[A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Di

1999
[Treatment of metastatic bone pain with Aredia(Pamidronate)].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1998, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Bone Neoplasms; Breast Neop

1998
[Pamidronate therapy for lung cancer patients with bone metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:7

    Topics: Aged; Analgesics, Opioid; Antineoplastic Agents; Bone Neoplasms; Diphosphonates; Female; Humans; Lun

2000
Positive effect of radiotherapy and surgery on hormonally active pulmonary metastases of primary parathyroid carcinoma.
    European journal of endocrinology, 2000, Volume: 143, Issue:6

    Topics: Antineoplastic Agents; Calcium; Combined Modality Therapy; Diphosphonates; Female; Follow-Up Studies

2000
[Analgesic effect of Pamidronate on bone pain in patient with hypertrophic pulmonary osteoarthropathy].
    Revue de pneumologie clinique, 2001, Volume: 57, Issue:3

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Carcinoma, Squamous Cell; Diphosphonates; Drug Admi

2001
Trastuzumab and breast cancer.
    The New England journal of medicine, 2001, Sep-27, Volume: 345, Issue:13

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2001
Pamidronate-induced remission of pain associated with hypertrophic pulmonary osteoarthropathy in chemoendocrine therapy-refractory inoperable metastatic breast carcinoma.
    Anti-cancer drugs, 2001, Volume: 12, Issue:9

    Topics: Adult; Breast Neoplasms; Diphosphonates; Female; Humans; Lung Neoplasms; Osteoarthropathy, Secondary

2001
Parathyroid hormone-related protein(50-69) and response to pamidronate therapy for tumour-induced hypercalcaemia.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Female; Humans; Hy

1991
Symptomatic hypercalcaemia in lung cancer.
    Respiratory medicine, 1991, Volume: 85, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcitonin; Diphosphonates; Drug Therapy, Combination; Female; Human

1991
Oral biphosphonate therapy in metastatic parathyroid carcinoma.
    Lancet (London, England), 1985, Jan-12, Volume: 1, Issue:8420

    Topics: Diphosphonates; Female; Humans; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Pamidronate

1985
Treatment of malignancy-associated hypercalcemia with intravenous aminohydroxypropylidene diphosphonate.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:8

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Calcium; Cyclic AMP; Diphosphonates; Female; Head and

1986
Treatment of refractory cancer-associated hypercalcemia with aminohydroxypropylidene diphosphonate.
    Acta medica Scandinavica, 1988, Volume: 224, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Diphosphonates; Female; Humans; Hypercalcemia; Lung Neoplasms

1988