Page last updated: 2024-11-02

pamidronate and Kidney Failure, Chronic

pamidronate has been researched along with Kidney Failure, Chronic in 29 studies

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"Secondary hyperparathyroidism may worsen after the administration of pamidronate in postmenopausal hemodialysis (HD) patients."9.16Effects of pamidronate and calcitriol on the set point of the parathyroid gland in postmenopausal hemodialysis patients with secondary hyperparathyroidism. ( Chu, P; Huang, CY; Lo, L; Lu, KC; Wu, CC; Zheng, CM, 2012)
"The aim of this study was to evaluate the efficacy and safety of pamidronate in HD patients affected by severe secondary hyperparathyroidism and moderate hypercalcemia who were receiving intravenous calcitriol (Calcijex)."9.10Usefulness of pamidronate in severe secondary hyperparathyroidism in patients undergoing hemodialysis. ( Fuster, D; Mas, M; Moreno, A; Torregrosa, JV; Ybarra, J, 2003)
" We report a case in which a patient with tertiary hyperparathyroidism and refractory hypercalcemia who was not a surgical candidate was managed with the bisphosphonate pamidronate."7.75Hypercalcemia associated with tertiary hyperparathyroidism managed conservatively with pamidronate in a hemodialysis patient. ( Canada, RB; Czosnowski, LM; Hudson, JQ, 2009)
"The purpose of this study is to evaluate the acute effect of pamidronate on plasma ionized calcium (iCa) level reduction and dynamic parathyroid hormone (PTH) secretion in postmenopausal hemodialysis-dependent women with secondary hyperparathyroidism."7.72Acute effect of pamidronate on PTH secretion in postmenopausal hemodialysis patients with secondary hyperparathyroidism. ( Chu, P; Lin, SH; Lin, YF; Lu, KC; Yeung, LK, 2003)
"Pamidronate 30 mg was given intravenously every 3 months after LT for the duration of 1 year to 43 patients with osteopenia or osteoporosis prior LT."6.73Pamidronate and osteoporosis prevention in liver transplant recipients. ( Fiore, CE; Giostra, E; Mentha, G; Pennisi, P; Rizzoli, R; Trombetti, A, 2007)
"BACKGROUND Hypercalcemia is a common complication in the intensive care unit (ICU)."5.48Use of Pamidronate to Treat Hypercalcemia in an Oncology Dialysis Patient: A Case Report. ( El Madhoun, I; El Zeer, HS; Khatib, M; Mahmoud, S; Mitwally, H, 2018)
"Secondary hyperparathyroidism may worsen after the administration of pamidronate in postmenopausal hemodialysis (HD) patients."5.16Effects of pamidronate and calcitriol on the set point of the parathyroid gland in postmenopausal hemodialysis patients with secondary hyperparathyroidism. ( Chu, P; Huang, CY; Lo, L; Lu, KC; Wu, CC; Zheng, CM, 2012)
"The aim of this study was to evaluate the efficacy and safety of pamidronate in HD patients affected by severe secondary hyperparathyroidism and moderate hypercalcemia who were receiving intravenous calcitriol (Calcijex)."5.10Usefulness of pamidronate in severe secondary hyperparathyroidism in patients undergoing hemodialysis. ( Fuster, D; Mas, M; Moreno, A; Torregrosa, JV; Ybarra, J, 2003)
" Calciphylaxis process started when she received calcium gluconate intravenously the day before the surgery to correct hypocalcemia and continued progressively despite peritoneal dialysis and forced stopping calcium-containing medication."3.81Successful treatment of calciphylaxis with pamidronate. ( Hooman, N; Jahangiri, F; Mehrazma, M; Naghshi-Zadiyan, R, 2015)
" We report a case in which a patient with tertiary hyperparathyroidism and refractory hypercalcemia who was not a surgical candidate was managed with the bisphosphonate pamidronate."3.75Hypercalcemia associated with tertiary hyperparathyroidism managed conservatively with pamidronate in a hemodialysis patient. ( Canada, RB; Czosnowski, LM; Hudson, JQ, 2009)
"The purpose of this study is to evaluate the acute effect of pamidronate on plasma ionized calcium (iCa) level reduction and dynamic parathyroid hormone (PTH) secretion in postmenopausal hemodialysis-dependent women with secondary hyperparathyroidism."3.72Acute effect of pamidronate on PTH secretion in postmenopausal hemodialysis patients with secondary hyperparathyroidism. ( Chu, P; Lin, SH; Lin, YF; Lu, KC; Yeung, LK, 2003)
"The successful use of pamidronate, a bisphosphonate, for the treatment of hypercalcemia and/or osteopenia is reported in three children with renal failure or following renal transplant."3.70The use of pamidronate in three children with renal disease. ( Rodd, C; Sellers, E; Sharma, A, 1998)
" Immunosuppression was cyclosporine and prednisolone, with no difference in dosing between the 2 groups."2.74Effect of pamidronate on bone loss after kidney transplantation: a randomized trial. ( Altmann, P; Andrews, C; Banks, LM; Cockwell, P; Cunningham, J; Dudley, C; Hall-Craggs, M; Noonan, K; Pattison, J; Sweny, P; Walsh, SB; Wilkie, M; Yaqoob, MM, 2009)
"Pamidronate 30 mg was given intravenously every 3 months after LT for the duration of 1 year to 43 patients with osteopenia or osteoporosis prior LT."2.73Pamidronate and osteoporosis prevention in liver transplant recipients. ( Fiore, CE; Giostra, E; Mentha, G; Pennisi, P; Rizzoli, R; Trombetti, A, 2007)
"Pamidronate treatment was associated with development of adynamic bone histology."2.71Prevention of bone loss in renal transplant recipients: a prospective, randomized trial of intravenous pamidronate. ( Bognar, I; Burris, L; Coco, M; Durkin, P; Faugere, MC; Figueroa, K; Glicklich, D; Greenstein, S; Malluche, H; McDonough, P; Schechner, R; Tellis, V; Wang, G, 2003)
"Very rapid bone loss, osteopenia and skeletal morbidity after renal transplantation have been well documented and found to occur in a sex dependent fashion."2.69Pamidronate therapy as prevention of bone loss following renal transplantation. ( Almond, MK; Ball, E; Cunningham, J; Evans, K; Fan, SL, 2000)
"Collapsing focal segmental glomerulosclerosis is well described in its idiopathic form, mostly seen in young African American patients, and in association with HIV virus."2.45[Bisphosphonate-induced collapsing focal segmental glomerulosclerosis; two clinical cases and literature review]. ( Jotterand, V; Martin, PY; Moll, S; Saudan, P, 2009)
"Hypocalcemia was treated with calcium and vitamin D3 supplements."2.44[Zoledronate-associated end stage renal failure and hypocalcaemia]. ( Bodmer, M; Kummer, O; Ramazzina, C; Rätz Bravo, AE; Zysset Aschmann, Y, 2007)
"BACKGROUND Hypercalcemia is a common complication in the intensive care unit (ICU)."1.48Use of Pamidronate to Treat Hypercalcemia in an Oncology Dialysis Patient: A Case Report. ( El Madhoun, I; El Zeer, HS; Khatib, M; Mahmoud, S; Mitwally, H, 2018)
"Calciphylaxis is an infrequent disease that almost exclusively affects patients with chronic kidney disease, although cases have been observed in patients without renal function impairment."1.48Sodium thiosulfate and pamidronate for treatment of calciphylaxis: case report. ( Alvarez, CL; Estifan Ksabji, J; Fernández Cañabate, S; Ortega Valin, L, 2018)
"Calciphylaxis is a rare complication of chronic renal failure mostly with poor prognosis."1.36Skin wounds associated with calciphylaxis in end-stage renal disease patients on dialysis. ( Sulková, SD; Válek, M, 2010)
"In the distal femur, a high-turnover renal osteodystrophy was found but pamidronate suppressed this bone turnover and increased bone mineral content."1.35Treatment of experimental renal osteodystrophy with pamidronate. ( Iwaniec, UT; Järvinen, TL; Jokihaara, J; Jolma, PM; Kannus, P; Kööbi, P; Mustonen, JT; Pörsti, IH; Saha, HH; Sievänen, H; Turner, RT, 2008)
"The pamidronate dose was increased to 60 mg once a week and was well tolerated."1.32Pamidronate in a girl with chronic renal insufficiency dependent on parenteral nutrition. ( Chesney, RW; Duke, JL; Frizzell, NK; Hak, EB; Jones, DP, 2003)
"Pamidronate was given to 10 patients with end stage renal failure who had become symptomatically hypercalcaemic due to the use of calcium based phosphate binders and alphacalcidol."1.29Treatment of hypercalcaemia with pamidronate in patients with end stage renal failure. ( Davenport, A; Goel, S; Mackenzie, JC, 1993)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (17.24)18.2507
2000's17 (58.62)29.6817
2010's7 (24.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jain, N1
Reilly, RF1
Mahmoud, S1
Mitwally, H1
El Zeer, HS1
El Madhoun, I1
Khatib, M1
Akhtar, J1
Gorantla, VK1
Snell, PD1
Wall, BM1
Fernández Cañabate, S1
Alvarez, CL1
Ortega Valin, L1
Estifan Ksabji, J1
Huang, CY1
Zheng, CM1
Wu, CC1
Lo, L1
Lu, KC2
Chu, P2
Hooman, N1
Naghshi-Zadiyan, R1
Mehrazma, M1
Jahangiri, F1
Jotterand, V1
Moll, S1
Martin, PY1
Saudan, P1
Czosnowski, LM1
Hudson, JQ1
Canada, RB1
Walsh, SB1
Altmann, P1
Pattison, J1
Wilkie, M1
Yaqoob, MM1
Dudley, C1
Cockwell, P1
Sweny, P1
Banks, LM1
Hall-Craggs, M1
Noonan, K1
Andrews, C1
Cunningham, J2
Sulková, SD1
Válek, M1
Saghafi, D1
Suzuki, Y3
Kuriyama, S1
Atsumi, Y1
Murata, C1
Matsuoka, K1
Taniyama, M1
Muramatsu, T1
Ohta, S1
Duke, JL1
Jones, DP1
Frizzell, NK1
Chesney, RW1
Hak, EB1
Torregrosa, JV1
Moreno, A1
Mas, M1
Ybarra, J1
Fuster, D1
Coco, M1
Glicklich, D1
Faugere, MC1
Burris, L1
Bognar, I1
Durkin, P1
Tellis, V1
Greenstein, S1
Schechner, R1
Figueroa, K1
McDonough, P1
Wang, G1
Malluche, H1
Yeung, LK1
Lin, SH2
Lin, YF1
Monney, P1
Nguyen, QV1
Perroud, H1
Descombes, E1
Cheng, CJ1
Chou, CH1
Trimarchi, H1
Lombi, F1
Forrester, M1
Elizondo, C1
Sawinski, D1
Pereyra, H1
Freixas, E1
Pennisi, P1
Trombetti, A1
Giostra, E1
Mentha, G1
Rizzoli, R1
Fiore, CE1
Ramazzina, C1
Zysset Aschmann, Y1
Kummer, O1
Rätz Bravo, AE1
Bodmer, M1
Jokihaara, J1
Pörsti, IH1
Kööbi, P1
Jolma, PM1
Mustonen, JT1
Saha, HH1
Sievänen, H1
Kannus, P1
Iwaniec, UT1
Turner, RT1
Järvinen, TL1
Garnero, P1
Grimaux, M1
Seguin, P1
Delmas, PD1
Davenport, A1
Goel, S1
Mackenzie, JC1
Sinha, RN1
Fraser, WD1
Casson, IF1
Sellers, E1
Sharma, A1
Rodd, C1
Fan, SL1
Almond, MK1
Ball, E1
Evans, K1
Svendsen, OL1
Yap, AS1
Hockings, GI1
Fleming, SJ1
Khafagi, FA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A 2 Year Prospective, Multicentre, Open-label, Randomised, Controlled Study to Investigate the Effectiveness of Pamidronate in the Prevention of Bone Loss in de Novo Renal Transplant Patients (With a PTH > 150pg/ml) on a Ciclosporin A and Glucocorticoid B[NCT00738257]Phase 4126 participants (Actual)Interventional2000-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for pamidronate and Kidney Failure, Chronic

ArticleYear
Hungry bone syndrome.
    Current opinion in nephrology and hypertension, 2017, Volume: 26, Issue:4

    Topics: Bone Density Conservation Agents; Bone Diseases, Metabolic; Calcitriol; Calcium; Diphosphonates; Hum

2017
[Bisphosphonate-induced collapsing focal segmental glomerulosclerosis; two clinical cases and literature review].
    Nephrologie & therapeutique, 2009, Volume: 5, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Diphosphonates; Female; Fractures, Spontaneous

2009
[Zoledronate-associated end stage renal failure and hypocalcaemia].
    Praxis, 2007, Apr-25, Volume: 96, Issue:17

    Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over;

2007

Trials

6 trials available for pamidronate and Kidney Failure, Chronic

ArticleYear
Effects of pamidronate and calcitriol on the set point of the parathyroid gland in postmenopausal hemodialysis patients with secondary hyperparathyroidism.
    Nephron. Clinical practice, 2012, Volume: 122, Issue:3-4

    Topics: Anti-Inflammatory Agents; Bone Density Conservation Agents; Calcitriol; Calcium; Calcium Channel Ago

2012
Effect of pamidronate on bone loss after kidney transplantation: a randomized trial.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:5

    Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Bone Density Conservation Agents; Bone Resorption;

2009
Usefulness of pamidronate in severe secondary hyperparathyroidism in patients undergoing hemodialysis.
    Kidney international. Supplement, 2003, Issue:85

    Topics: Aged; Bone Density; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyroidism, Secondary; K

2003
Prevention of bone loss in renal transplant recipients: a prospective, randomized trial of intravenous pamidronate.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:10

    Topics: Adult; Anti-Inflammatory Agents; Biopsy; Bone Density; Diphosphonates; Female; Hormones; Humans; Imm

2003
Pamidronate and osteoporosis prevention in liver transplant recipients.
    Rheumatology international, 2007, Volume: 27, Issue:3

    Topics: Adult; Aged; Bone Density; Bone Density Conservation Agents; Calcification, Physiologic; Diphosphona

2007
Pamidronate therapy as prevention of bone loss following renal transplantation.
    Kidney international, 2000, Volume: 57, Issue:2

    Topics: Absorptiometry, Photon; Adult; Aged; Alkaline Phosphatase; Aluminum; Anti-Inflammatory Agents; Bone

2000

Other Studies

20 other studies available for pamidronate and Kidney Failure, Chronic

ArticleYear
Use of Pamidronate to Treat Hypercalcemia in an Oncology Dialysis Patient: A Case Report.
    The American journal of case reports, 2018, Sep-13, Volume: 19

    Topics: Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Female; Humans; Hypercalcemia; K

2018
Acute esophageal necrosis (black esophagus) complicating calcific uremic arteriolopathy
.
    Clinical nephrology, 2019, Volume: 91, Issue:1

    Topics: Acute Disease; Aged; Arterioles; Bone Density Conservation Agents; Esophagitis; Esophagoscopy; Esoph

2019
Sodium thiosulfate and pamidronate for treatment of calciphylaxis: case report.
    Colombia medica (Cali, Colombia), 2018, Dec-30, Volume: 49, Issue:4

    Topics: Administration, Intravenous; Aged; Calciphylaxis; Chelating Agents; Drug Therapy, Combination; Femal

2018
Successful treatment of calciphylaxis with pamidronate.
    Iranian journal of kidney diseases, 2015, Volume: 9, Issue:1

    Topics: Biopsy; Calciphylaxis; Calcium Gluconate; Debridement; Diphosphonates; Female; Humans; Hypocalcemia;

2015
Hypercalcemia associated with tertiary hyperparathyroidism managed conservatively with pamidronate in a hemodialysis patient.
    The American journal of the medical sciences, 2009, Volume: 337, Issue:4

    Topics: Aged; Calcium; Diphosphonates; Humans; Hypercalcemia; Hyperparathyroidism; Kidney Failure, Chronic;

2009
Skin wounds associated with calciphylaxis in end-stage renal disease patients on dialysis.
    Nutrition (Burbank, Los Angeles County, Calif.), 2010, Volume: 26, Issue:9

    Topics: Aged; Anti-Inflammatory Agents; Calciphylaxis; Cinacalcet; Diphosphonates; Female; Humans; Hyperpara

2010
Use of bisphosphonates in patients with myeloma and renal failure.
    Mayo Clinic proceedings, 2003, Volume: 78, Issue:1

    Topics: Antineoplastic Agents; Bone Remodeling; Chronic Kidney Disease-Mineral and Bone Disorder; Contraindi

2003
Maternal inheritance of diabetes is associated with inactive ALDH2 genotype in diabetics with renal failure in Japanese.
    Diabetes research and clinical practice, 2003, Volume: 60, Issue:2

    Topics: Adult; Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Body Mass Index; Diabeti

2003
Pamidronate in a girl with chronic renal insufficiency dependent on parenteral nutrition.
    Pediatric nephrology (Berlin, Germany), 2003, Volume: 18, Issue:7

    Topics: Anti-Inflammatory Agents; Calcitonin; Child; Chlorothiazide; Colonic Diseases; Diphosphonates; Diure

2003
Acute effect of pamidronate on PTH secretion in postmenopausal hemodialysis patients with secondary hyperparathyroidism.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:6

    Topics: Aged; Chronic Kidney Disease-Mineral and Bone Disorder; Diphosphonates; Female; Humans; Hypercalcemi

2003
Rapid improvement of calciphylaxis after intravenous pamidronate therapy in a patient with chronic renal failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:8

    Topics: Anti-Inflammatory Agents; C-Reactive Protein; Calciphylaxis; Diphosphonates; Female; Humans; Infusio

2004
An unrecognized cause of recurrent hypercalcemia: immobilization.
    Southern medical journal, 2006, Volume: 99, Issue:4

    Topics: Aged; Bone Density Conservation Agents; Calcium; Diphosphonates; Exercise Therapy; Gout; Humans; Hyp

2006
Disodium pamidronate for treating severe hypercalcemia in a hemodialysis patient.
    Nature clinical practice. Nephrology, 2006, Volume: 2, Issue:8

    Topics: Antineoplastic Agents; Diphosphonates; Humans; Hypercalcemia; Kidney Failure, Chronic; Male; Middle

2006
Treatment of experimental renal osteodystrophy with pamidronate.
    Kidney international, 2008, Volume: 74, Issue:3

    Topics: Animals; Bone Demineralization, Pathologic; Bone Density; Bone Remodeling; Chronic Kidney Disease-Mi

2008
Characterization of immunoreactive forms of human osteocalcin generated in vivo and in vitro.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Bone Diseases, Metabolic; Bone Neoplasms; Cell Line; Diphosphonates;

1994
Treatment of hypercalcaemia with pamidronate in patients with end stage renal failure.
    Scandinavian journal of urology and nephrology, 1993, Volume: 27, Issue:4

    Topics: Calcium Carbonate; Diphosphonates; Female; Humans; Hydroxycholecalciferols; Hypercalcemia; Kidney Fa

1993
Long-term management of hypercalcaemia in chronically active sarcoidosis.
    Journal of the Royal Society of Medicine, 1997, Volume: 90, Issue:3

    Topics: Adult; Chronic Disease; Diphosphonates; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Hy

1997
The use of pamidronate in three children with renal disease.
    Pediatric nephrology (Berlin, Germany), 1998, Volume: 12, Issue:9

    Topics: Adolescent; Anti-Inflammatory Agents; Bone Density; Bone Diseases, Metabolic; Child; Diphosphonates;

1998
Statistical error in pamidronate study?
    Kidney international, 2000, Volume: 58, Issue:1

    Topics: Anti-Inflammatory Agents; Diphosphonates; Humans; Kidney Failure, Chronic; Kidney Transplantation; P

2000
Use of aminohydroxypropylidene bisphosphonate (AHPrBP, "APD") for the treatment of hypercalcemia in patients with renal impairment.
    Clinical nephrology, 1990, Volume: 34, Issue:5

    Topics: Acute Kidney Injury; Adult; Diphosphonates; Female; Humans; Hypercalcemia; Kidney Failure, Chronic;

1990