pamidronate has been researched along with Giant Cell Tumor of Bone in 3 studies
Giant Cell Tumor of Bone: A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Giant cell tumor of bone is an aggressive tumor characterized by extensive bone destruction and high recurrence rates." | 1.32 | Bisphosphonates may reduce recurrence in giant cell tumor by inducing apoptosis. ( Blaine, TA; Chang, SS; Doppelt, JD; Jung, KM; Kim, TW; Lee, FY; Suratwala, SJ; Winchester, RJ; Zhang, HZ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lau, CP | 1 |
| Huang, L | 2 |
| Tsui, SK | 1 |
| Ng, PK | 1 |
| Leung, PY | 1 |
| Kumta, SM | 2 |
| Cheng, YY | 1 |
| Lee, KM | 1 |
| Xu, JK | 1 |
| Zheng, MH | 1 |
| Chang, SS | 1 |
| Suratwala, SJ | 1 |
| Jung, KM | 1 |
| Doppelt, JD | 1 |
| Zhang, HZ | 1 |
| Blaine, TA | 1 |
| Kim, TW | 1 |
| Winchester, RJ | 1 |
| Lee, FY | 1 |
3 other studies available for pamidronate and Giant Cell Tumor of Bone
| Article | Year |
|---|---|
Pamidronate, farnesyl transferase, and geranylgeranyl transferase-I inhibitors affects cell proliferation, apoptosis, and OPG/RANKL mRNA expression in stromal cells of giant cell tumor of bone.
Topics: Alkyl and Aryl Transferases; Apoptosis; Benzamides; Bone Density Conservation Agents; Bone Neoplasms | 2011 |
Bisphosphonates induce apoptosis of stromal tumor cells in giant cell tumor of bone.
Topics: Alendronate; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Diphosphonates; DNA Fragmentation; DN | 2004 |
Bisphosphonates may reduce recurrence in giant cell tumor by inducing apoptosis.
Topics: Annexin A5; Apoptosis; Bone Neoplasms; Caspase 3; Caspases; Diphosphonates; Dose-Response Relationsh | 2004 |