pamidronate has been researched along with Gaucher Disease in 7 studies
Gaucher Disease: An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It could be posited that pamidronate exerted a positive protective effect on the mother's skeleton with no evidence of adverse effects on pregnancy or on the baby's health to date." | 3.76 | Intravenous bisphosphonate treatment and pregnancy: its effects on mother and infant bone health. ( Mastaglia, SR; Oliveri, B; Watman, NP, 2010) |
| "Gaucher disease is the most prevalent lysosomal storage disorder." | 1.29 | Aminohydroxypropylidene-biphosphonate in the treatment of bone lesions in a case of Gaucher's disease type 3. ( Agosti, E; Bembi, B; Boehm, P; Nassimbeni, G; Vidoni, L; Zanatta, M, 1994) |
| "Two patients with Type 1 (adult) Gaucher's disease and major skeletal involvement with multiple fractures have been treated with the second generation bisphosphonate pamidronate for extensive periods." | 1.28 | Treatment of type 1 Gaucher's disease affecting bone with aminohydroxypropylidene bisphosphonate (pamidronate). ( Hesp, R; Hulme, P; Meunier, PJ; Ostlere, L; Reeve, J; Warner, T; Watts, RW, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mastaglia, SR | 1 |
| Watman, NP | 1 |
| Oliveri, B | 1 |
| Abe, M | 1 |
| Minoguchi, M | 1 |
| Jinbo, J | 1 |
| Kikuchi, Y | 1 |
| Chiba, A | 1 |
| Shibata, Y | 1 |
| Kogo, Y | 1 |
| Harinck, HI | 1 |
| Bijvoet, OL | 1 |
| van der Meer, JW | 1 |
| Jones, B | 1 |
| Onvlee, GJ | 1 |
| Samuel, R | 1 |
| Katz, K | 1 |
| Papapoulos, SE | 1 |
| Yosipovitch, Z | 1 |
| Zaizov, R | 1 |
| Liberman, UA | 1 |
| Bembi, B | 2 |
| Agosti, E | 1 |
| Boehm, P | 1 |
| Nassimbeni, G | 1 |
| Zanatta, M | 1 |
| Vidoni, L | 1 |
| Ciana, G | 1 |
| Cuttini, M | 1 |
| Ostlere, L | 1 |
| Warner, T | 1 |
| Meunier, PJ | 1 |
| Hulme, P | 1 |
| Hesp, R | 1 |
| Watts, RW | 1 |
| Reeve, J | 1 |
7 other studies available for pamidronate and Gaucher Disease
| Article | Year |
|---|---|
Intravenous bisphosphonate treatment and pregnancy: its effects on mother and infant bone health.
Topics: Bone Density; Bone Density Conservation Agents; Diphosphonates; Female; Follow-Up Studies; Gaucher D | 2010 |
[Gaucher disease with multiple bone necrosis treated by enzyme replacement therapy and pamidronate].
Topics: Adult; Diphosphonates; Dose-Response Relationship, Drug; Drug Administration Schedule; Gaucher Disea | 2004 |
Regression of bone lesions in Gaucher's disease during treatment with aminohydroxypropylidene bisphosphonate.
Topics: Adolescent; Bone and Bones; Diphosphonates; Gaucher Disease; Humans; Male; Pamidronate | 1984 |
Aminohydroxy propylidene bisphosphonate (APD) treatment improves the clinical skeletal manifestations of Gaucher's disease.
Topics: Adolescent; Bone Diseases; Diphosphonates; Female; Femur; Follow-Up Studies; Fractures, Spontaneous; | 1994 |
Aminohydroxypropylidene-biphosphonate in the treatment of bone lesions in a case of Gaucher's disease type 3.
Topics: Bone Diseases; Child, Preschool; Diphosphonates; Female; Gaucher Disease; Humans; Pamidronate | 1994 |
Short-term effects of pamidronate in patients with Gaucher's disease and severe skeletal involvement.
Topics: Adult; Bone Density; Bone Remodeling; Diphosphonates; Female; Gaucher Disease; Humans; Male; Middle | 1997 |
Treatment of type 1 Gaucher's disease affecting bone with aminohydroxypropylidene bisphosphonate (pamidronate).
Topics: Adult; Bone and Bones; Bone Density; Bone Diseases; Bone Marrow; Calcium; Diphosphonates; Female; Ga | 1991 |