Page last updated: 2024-11-02

pamidronate and Femoral Fractures

pamidronate has been researched along with Femoral Fractures in 11 studies

Femoral Fractures: Fractures of the femur.

Research Excerpts

ExcerptRelevanceReference
"The multidisciplinary, rational approach, which involves early surgical intramedullary fixation of fractures with subsequent rehabilitation and Pamidronate administration, is considered to provide a more effective therapy with better results and therefore better quality of life in patients with osteogenesis imperfecta."3.74[Role of an interdisciplinary approach in the healing of long bone fractures in patients with osteogenesis imperfecta]. ( Kokavec, M; Novorolský, K; Pribilincová, Z, 2008)
" At this point, closed fractures were made using an Einhorn apparatus, and bisphosphonate dosing was continued until the experimental endpoint."1.56Pretreatment with Pamidronate Decreases Bone Formation but Increases Callus Bone Volume in a Rat Closed Fracture Model. ( Little, DG; McDonald, MM; Mikulec, K; Morse, A; Munns, CF; Schindeler, A, 2020)
"Pamidronate was discontinued after 7 years of therapy, following which she sustained two further nontraumatic femur fractures, and continued to show delayed tibial osteotomy healing."1.43Recurrent Proximal Femur Fractures in a Teenager With Osteogenesis Imperfecta on Continuous Bisphosphonate Therapy: Are We Overtreating? ( Bishop, NJ; Högler, W; Sanghrajka, A; Vasanwala, RF, 2016)
" These traceable BPs were dosed to Wistar rats in models of normal growth and closed fracture repair."1.42PTH(1-34) Treatment Increases Bisphosphonate Turnover in Fracture Repair in Rats. ( Cantrill, LC; Little, DG; Mikulec, K; Murphy, CM; Peacock, L; Schindeler, A, 2015)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's7 (63.64)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Morse, A1
McDonald, MM1
Mikulec, K2
Schindeler, A2
Munns, CF1
Little, DG3
Chen, Y1
Sebag, M1
Powell, TI1
Morin, SN1
Kumar, G1
Dunlop, CC1
Murphy, CM1
Cantrill, LC1
Peacock, L1
Palomo, T1
Fassier, F1
Ouellet, J1
Sato, A1
Montpetit, K1
Glorieux, FH1
Rauch, F1
Vasanwala, RF1
Sanghrajka, A1
Bishop, NJ2
Högler, W1
Menzdorf, L1
Weuster, M1
Klüter, T1
Brüggemann, S1
Behrendt, P1
Fitchen-Oestern, S1
Varoga, D1
Seekamp, A1
Purcz, N1
Glueer, CC1
Pufe, T1
Lippross, S1
Kokavec, M1
Novorolský, K1
Pribilincová, Z1
Arundel, P1
Offiah, A1
Kumar, D1
Kumar, V1
Howman-Giles, RB1
Wong, E1
Ali, SO1
Ward, KA1
Adams, JE1
Freemont, TJ1
Mughal, MZ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Intraoperative Use of Tranexamic Acid in Reducing Blood Loss During Telescoping Nail Application in Osteogenesis Imperfecta - Randomized Control Trials[NCT05321199]20 participants (Actual)Interventional2022-05-01Completed
Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation[NCT02074631]Phase 280 participants (Actual)Interventional2015-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

11 other studies available for pamidronate and Femoral Fractures

ArticleYear
Pretreatment with Pamidronate Decreases Bone Formation but Increases Callus Bone Volume in a Rat Closed Fracture Model.
    Calcified tissue international, 2020, Volume: 106, Issue:2

    Topics: Animals; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Bony Callus; Disease Model

2020
Atypical femur fracture in a woman with osteogenesis imperfecta and multiple myeloma.
    Journal of musculoskeletal & neuronal interactions, 2018, 09-01, Volume: 18, Issue:3

    Topics: Bone Density Conservation Agents; Diphosphonates; Female; Femoral Fractures; Humans; Middle Aged; Mu

2018
Effects of bilateral distal femoral stress in a patient on long-term pamidronate.
    American journal of orthopedics (Belle Mead, N.J.), 2013, Volume: 42, Issue:7

    Topics: Accidental Falls; Bone Density Conservation Agents; Diphosphonates; Female; Femoral Fractures; Fract

2013
PTH(1-34) Treatment Increases Bisphosphonate Turnover in Fracture Repair in Rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2015, Volume: 30, Issue:6

    Topics: Animals; Carbon Isotopes; Diphosphonates; Femoral Fractures; Fracture Healing; Imidazoles; Isotope L

2015
Intravenous Bisphosphonate Therapy of Young Children With Osteogenesis Imperfecta: Skeletal Findings During Follow Up Throughout the Growing Years.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2015, Volume: 30, Issue:12

    Topics: Absorptiometry, Photon; Adolescent; Anthropometry; Bone and Bones; Bone Density; Bone Density Conser

2015
Recurrent Proximal Femur Fractures in a Teenager With Osteogenesis Imperfecta on Continuous Bisphosphonate Therapy: Are We Overtreating?
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016, Volume: 31, Issue:7

    Topics: Adolescent; Child; Child, Preschool; Diphosphonates; Female; Femoral Fractures; Humans; Osteogenesis

2016
Local pamidronate influences fracture healing in a rodent femur fracture model: an experimental study.
    BMC musculoskeletal disorders, 2016, 06-09, Volume: 17

    Topics: Animals; Bone Density Conservation Agents; Collagen; Diphosphonates; Disease Models, Animal; Female;

2016
[Role of an interdisciplinary approach in the healing of long bone fractures in patients with osteogenesis imperfecta].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2008, Volume: 75, Issue:3

    Topics: Adolescent; Bone Density Conservation Agents; Child; Child, Preschool; Diphosphonates; Female; Femor

2008
Evolution of the radiographic appearance of the metaphyses over the first year of life in type V osteogenesis imperfecta: clues to pathogenesis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011, Volume: 26, Issue:4

    Topics: Arm Bones; Bone Density Conservation Agents; Bone Diseases, Metabolic; Cranial Fontanelles; Diphosph

2011
Evaluation of biodistribution by local versus systemic administration of 99mTc-labeled pamidronate.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2006, Volume: 11, Issue:5

    Topics: Administration, Topical; Animals; Bone Density Conservation Agents; Diphosphonates; Disease Models,

2006
Can bisphosphonate treatment be stopped in a growing child with skeletal fragility?
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2007, Volume: 18, Issue:8

    Topics: Accidental Falls; Bone Density; Bone Density Conservation Agents; Child, Preschool; Diphosphonates;

2007