Page last updated: 2024-11-02

pamidronate and Benign Neoplasms

pamidronate has been researched along with Benign Neoplasms in 107 studies

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy and safety of ibandronate and pamidronate in patients with hypercalcemia of malignancy (HCM)."9.10Efficacy and safety of ibandronate in the treatment of hypercalcemia of malignancy: a randomized multicentric comparison to pamidronate. ( Bergström, B; Pecherstorfer, M; Rizzoli, R; Steinhauer, EU; Wetterwald, M, 2003)
"We have conducted a randomized crossover comparative trial of a single-dose course of disodium (3-amino-1-hydroxypropylidene) bisphosphonate pentahydrate (pamidronate) and plicamycin in 48 patients with a first occurrence of tumor-related hypercalcemia."9.07Plicamycin and pamidronate in symptomatic tumor-related hypercalcemia: a prospective randomized crossover trial. ( Senn, HJ; Thiébaud, D; Thürlimann, B; Waldburger, R, 1992)
"A single-dose infusion of 60 to 90 mg of pamidronate was highly effective and well tolerated and normalized corrected serum calcium in nearly all patients (61% to 100%) with hypercalcemia of malignancy."9.07Single-dose intravenous therapy with pamidronate for the treatment of hypercalcemia of malignancy: comparison of 30-, 60-, and 90-mg dosages. ( Chapman, R; Gagel, RF; Henderson, IC; Mallette, LE; Nussbaum, SR; Vandepol, CJ; Younger, J; Zubler, MA, 1993)
"A 4-hour infusion of pamidronate disodium, 60 mg, was as safe and effective as a 24-hour infusion, and both were superior to saline alone in lowering corrected serum calcium concentrations in patients with cancer-associated hypercalcemia."9.07Treatment of cancer-associated hypercalcemia. Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone. ( Ahmann, F; Chapman, R; Gill, I; Gucalp, R; Heffernan, M; Knight, RD; Madajewicz, S; Navari, R; Theriault, R; Zelenakas, K, 1994)
"This multicenter, double-blind, randomized trial was performed to determine the efficacy and safety of pamidronate disodium (APD) in comparison to etidronate disodium (EHDP) in the treatment of cancer-related hypercalcemia."9.07Comparative study of pamidronate disodium and etidronate disodium in the treatment of cancer-related hypercalcemia. ( Gucalp, R; Keller, A; Mallette, LE; Neidhart, J; Richman, SP; Ritch, P; Sarma, PR; Siegel, R; Tauer, K; Wiernik, PH, 1992)
"Given the superior efficacy and comparable safety profile of zoledronic acid compared with pamidronate disodium, zoledronic acid is likely to become the treatment of choice for hypercalcemia of malignancy."8.81The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy. ( Major, P, 2002)
"Zoledronic acid is superior to pamidronate; 4 mg is the dose recommended for initial treatment of HCM and 8 mg for relapsed or refractory hypercalcemia."8.81Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials. ( Abdi, E; Bell, R; Body, J; Hon, J; Lortholary, A; Major, P; Menssen, HD; Mills, G; Quebe-Fehling, E; Seaman, J; Yunus, F, 2001)
"The primary objective was to compare the incidence of acute kidney injury (AKI) within 7 days of receiving pamidronate for the treatment of HCM with pre-existing renal dysfunction versus normal renal function at the time of pamidronate administration."8.02Use of Pamidronate for Hypercalcemia of Malignancy in Renal Dysfunction. ( Norman, SJ; Reeves, DJ; Saum, LM, 2021)
"A time-motion study was performed by evaluating time and use of medical supply resources in the administration of zoledronic acid and pamidronate as palliative care of tumor-induced osteolysis within the clinical setting of three Italian oncology day-hospital sites."7.74[Cost analysis of tumor-induced osteolysis treated with intravenous zoledronic acid and pamidronate: a time-motion study]. ( Baldini, E; Berto, P; Cortesi, E; Dauria, G; Roila, F; Schivazappa, C, 2007)
"Pamidronate at a dose of 1 mg/kg is a safe and effective treatment for severe, refractory hypercalcemia of malignancy in children."7.70Use of pamidronate in the management of acute cancer-related hypercalcemia in children. ( Shende, A; Young, G, 1998)
"The purpose of this study was to investigate the effects of pamidronate, a second generation bisphosphonate, on the change in calcium homeostasis in patients with tumor-associated hypercalcemia."7.69Pamidronate treatment in patients with tumor-associated hypercalcemia: pharmacological effects and pharmacokinetics. ( Ariyoshi, Y; Hasegawa, H; Niinomi, M; Oiso, Y; Sakiyama, N; Takano, T; Tomita, A; Yamamoto, M, 1994)
"Pamidronate (APD) is a drug widely used for the treatment of hypercalcemia of malignancy."7.69Safety of pamidronate in patients with renal failure and hypercalcemia. ( Flombaum, CD; Machado, CE, 1996)
"The effect of lowering ionized calcium on circulating parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) was assessed in twenty patients with hypercalcemia of malignancy following treatment with Pamidronate Disodium."7.68Circulating PTH and PTHrP levels before and after treatment of tumor induced hypercalcemia with Pamidronate Disodium (APD). ( Grill, V; Ho, PW; Jerums, G; Martin, TJ; Murray, RM; Pitt, P; Potts, C; Santamaria, JD, 1992)
"Seventeen patients with malignant hypercalcemia were treated with a combination of a single dose of 3-amino 1-hydroxypropylidene-1-bisphosphonate (APD [also known as AHPrBP or palmidronate disodium]) and salmon calcitonin given as suppositories for 3 days."7.68Fast and effective treatment of malignant hypercalcemia. Combination of suppositories of calcitonin and a single infusion of 3-amino 1-hydroxypropylidene-1-bisphosphonate. ( Burckhardt, P; Jacquet, AF; Thiébaud, D, 1990)
"Pamidronate was given in a single infusion on day 0, the dose of pamidronate adapted to the severity of hypercalcemia."6.67[Pamidronate in the treatment of tumor-associated hypercalcemia]. ( Bosse, C; Fortelny, A; Gerber, E; Janisch, S; Lenzhofer, R; Marosi, C; Pecherstorfer, M; Rainer, H; Schratzberger, W; Wogritsch, C, 1991)
" infusion of pamidronate 90 mg in the treatment of malignant hypercalcemia."5.10Clodronate as a single-dose intravenous infusion effectively provides short-term correction of malignant hypercalcemia. ( Atula, ST; Nevalainen, JI; Pylkkänen, LH; Tähtelä, RK, 2003)
"To compare the efficacy and safety of ibandronate and pamidronate in patients with hypercalcemia of malignancy (HCM)."5.10Efficacy and safety of ibandronate in the treatment of hypercalcemia of malignancy: a randomized multicentric comparison to pamidronate. ( Bergström, B; Pecherstorfer, M; Rizzoli, R; Steinhauer, EU; Wetterwald, M, 2003)
"Bisphosphonates are now the standard treatment for tumor-induced hypercalcemia (TIH), and pamidronate can normalize serum Ca in at least 90% of the patients treated for the first time."5.09Decreased efficacy of bisphosphonates for recurrences of tumor-induced hypercalcemia. ( Body, JJ; Dumon, JC; Louviaux, I, 2000)
"A 4-hour infusion of pamidronate disodium, 60 mg, was as safe and effective as a 24-hour infusion, and both were superior to saline alone in lowering corrected serum calcium concentrations in patients with cancer-associated hypercalcemia."5.07Treatment of cancer-associated hypercalcemia. Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone. ( Ahmann, F; Chapman, R; Gill, I; Gucalp, R; Heffernan, M; Knight, RD; Madajewicz, S; Navari, R; Theriault, R; Zelenakas, K, 1994)
"This multicenter, double-blind, randomized trial was performed to determine the efficacy and safety of pamidronate disodium (APD) in comparison to etidronate disodium (EHDP) in the treatment of cancer-related hypercalcemia."5.07Comparative study of pamidronate disodium and etidronate disodium in the treatment of cancer-related hypercalcemia. ( Gucalp, R; Keller, A; Mallette, LE; Neidhart, J; Richman, SP; Ritch, P; Sarma, PR; Siegel, R; Tauer, K; Wiernik, PH, 1992)
"A single-dose infusion of 60 to 90 mg of pamidronate was highly effective and well tolerated and normalized corrected serum calcium in nearly all patients (61% to 100%) with hypercalcemia of malignancy."5.07Single-dose intravenous therapy with pamidronate for the treatment of hypercalcemia of malignancy: comparison of 30-, 60-, and 90-mg dosages. ( Chapman, R; Gagel, RF; Henderson, IC; Mallette, LE; Nussbaum, SR; Vandepol, CJ; Younger, J; Zubler, MA, 1993)
"We have conducted a randomized crossover comparative trial of a single-dose course of disodium (3-amino-1-hydroxypropylidene) bisphosphonate pentahydrate (pamidronate) and plicamycin in 48 patients with a first occurrence of tumor-related hypercalcemia."5.07Plicamycin and pamidronate in symptomatic tumor-related hypercalcemia: a prospective randomized crossover trial. ( Senn, HJ; Thiébaud, D; Thürlimann, B; Waldburger, R, 1992)
"Of 73 patients, 68 (93%) were treated with pamidronate or zoledronate; 69 (94%) patients suffered from malignant diseases, 3 (5%) had osteoporosis, and 1 (1%) had Paget's disease."4.83[Bisphosphonate-associated osteonecrosis of the jaw]. ( Abu-Id, MH; Açil, Y; Gottschalk, J; Kreusch, T, 2006)
"Given the superior efficacy and comparable safety profile of zoledronic acid compared with pamidronate disodium, zoledronic acid is likely to become the treatment of choice for hypercalcemia of malignancy."4.81The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy. ( Major, P, 2002)
"Zoledronic acid is superior to pamidronate; 4 mg is the dose recommended for initial treatment of HCM and 8 mg for relapsed or refractory hypercalcemia."4.81Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials. ( Abdi, E; Bell, R; Body, J; Hon, J; Lortholary, A; Major, P; Menssen, HD; Mills, G; Quebe-Fehling, E; Seaman, J; Yunus, F, 2001)
"Recent information on the pathophysiology and treatment of hypercalcemia of malignancy is reviewed, and the roles of two new agents, gallium nitrate and pamidronate, are discussed."4.78Update on the medical treatment of hypercalcemia of malignancy. ( Hall, TG; Schaiff, RA, 1993)
"The primary objective was to compare the incidence of acute kidney injury (AKI) within 7 days of receiving pamidronate for the treatment of HCM with pre-existing renal dysfunction versus normal renal function at the time of pamidronate administration."4.02Use of Pamidronate for Hypercalcemia of Malignancy in Renal Dysfunction. ( Norman, SJ; Reeves, DJ; Saum, LM, 2021)
"A time-motion study was performed by evaluating time and use of medical supply resources in the administration of zoledronic acid and pamidronate as palliative care of tumor-induced osteolysis within the clinical setting of three Italian oncology day-hospital sites."3.74[Cost analysis of tumor-induced osteolysis treated with intravenous zoledronic acid and pamidronate: a time-motion study]. ( Baldini, E; Berto, P; Cortesi, E; Dauria, G; Roila, F; Schivazappa, C, 2007)
"Pamidronate at a dose of 1 mg/kg is a safe and effective treatment for severe, refractory hypercalcemia of malignancy in children."3.70Use of pamidronate in the management of acute cancer-related hypercalcemia in children. ( Shende, A; Young, G, 1998)
"Pamidronate (APD) is a drug widely used for the treatment of hypercalcemia of malignancy."3.69Safety of pamidronate in patients with renal failure and hypercalcemia. ( Flombaum, CD; Machado, CE, 1996)
"We reviewed our experience with pamidronate in 160 patients with tumour-induced hypercalcemia (TIH) persisting after rehydration, particularly the influence of the dose administered, the tumour type and the presence of bone metastatic involvement on the calcaemic and calciuric response to pamidronate therapy."3.69Treatment of tumour-induced hypercalcaemia with the bisphosphonate pamidronate: dose-response relationship and influence of tumour type. ( Body, JJ; Dumon, JC, 1994)
"The purpose of this study was to investigate the effects of pamidronate, a second generation bisphosphonate, on the change in calcium homeostasis in patients with tumor-associated hypercalcemia."3.69Pamidronate treatment in patients with tumor-associated hypercalcemia: pharmacological effects and pharmacokinetics. ( Ariyoshi, Y; Hasegawa, H; Niinomi, M; Oiso, Y; Sakiyama, N; Takano, T; Tomita, A; Yamamoto, M, 1994)
"Seventeen patients with malignant hypercalcemia were treated with a combination of a single dose of 3-amino 1-hydroxypropylidene-1-bisphosphonate (APD [also known as AHPrBP or palmidronate disodium]) and salmon calcitonin given as suppositories for 3 days."3.68Fast and effective treatment of malignant hypercalcemia. Combination of suppositories of calcitonin and a single infusion of 3-amino 1-hydroxypropylidene-1-bisphosphonate. ( Burckhardt, P; Jacquet, AF; Thiébaud, D, 1990)
"The effect of lowering ionized calcium on circulating parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) was assessed in twenty patients with hypercalcemia of malignancy following treatment with Pamidronate Disodium."3.68Circulating PTH and PTHrP levels before and after treatment of tumor induced hypercalcemia with Pamidronate Disodium (APD). ( Grill, V; Ho, PW; Jerums, G; Martin, TJ; Murray, RM; Pitt, P; Potts, C; Santamaria, JD, 1992)
"Hypercalcemia of malignancy is associated with poor survival."2.82Hypercalcemia: A Review. ( Shane, E; Walker, MD, 2022)
"Twenty-five consecutive cancer patients with bone metastases treated monthly with disodium pamidronate infusion were evaluated prospectively for circulating levels of vascular endothelial growth factor (VEGF), gamma-IFN, interleukin (IL)-6, and IL-8 at different time points: just before and after 1, 2, and 7 days after pamidronate infusion."2.70Pamidronate induces modifications of circulating angiogenetic factors in cancer patients. ( Avvisati, G; Battistoni, F; Denaro, V; Dicuonzo, G; Gavasci, M; Salerno, A; Santini, D; Tonini, G; Vincenzi, B, 2002)
"Pamidronate was given in a single infusion on day 0, the dose of pamidronate adapted to the severity of hypercalcemia."2.67[Pamidronate in the treatment of tumor-associated hypercalcemia]. ( Bosse, C; Fortelny, A; Gerber, E; Janisch, S; Lenzhofer, R; Marosi, C; Pecherstorfer, M; Rainer, H; Schratzberger, W; Wogritsch, C, 1991)
"Hypercalcemia of malignancy (HM) is one of the commonest metabolic complications associated with cancer."2.67Significance of plasma PTH-rp in patients with hypercalcemia of malignancy treated with bisphosphonate. ( Wimalawansa, SJ, 1994)
"Thirty-nine patients with cancer-associated hypercalcaemia were randomly allocated to receive aminohydroxypropylidene diphosphonate (APD), mithramycin, or corticosteroids and salmon calcitonin."2.66Comparison of aminohydroxypropylidene diphosphonate, mithramycin, and corticosteroids/calcitonin in treatment of cancer-associated hypercalcaemia. ( Boyle, IT; Cowan, RA; Dryburgh, FJ; Gardner, MD; Jenkins, AS; Ralston, SH, 1985)
"Thirty-three cancer patients remaining hypercalcemic after a 48-h rehydration period were included and monitored daily until normocalcemia or treatment failure was documented."2.66Aminohydroxypropylidene bisphosphonate (APD) treatment for tumor-associated hypercalcemia: a randomized comparison between a 3-day treatment and single 24-hour infusions. ( Body, JJ; Borkowski, A; Magritte, A; Sculier, JP; Seraj, F, 1989)
"The results demonstrated that increased bone resorption is the major contributory factor and that inhibition with bisphosphonate normalizes the serum calcium concentration within five days in more than 90 percent of patients."2.66Role of bone and kidney in tumor-induced hypercalcemia and its treatment with bisphosphonate and sodium chloride. ( Bijvoet, OL; Body, JJ; Elte, JW; Harinck, HI; Neijt, JP; Plantingh, AS; Sleeboom, HP; Wildiers, J, 1987)
"Indomethacin was effective in only one of five patients to whom it was given, and EHDP was effective also in only one of five patients."2.65Comparative study of available medical therapy for hypercalcemia of malignancy. ( Heath, DA; Mundy, GR; Wilkinson, R, 1983)
"Recurrent hypercalcemia is nevertheless difficult to control and antibodies against parathyroid hormone-related protein could be useful for that matter in selected patients who are not in the terminal stage of their disease."2.42Hypercalcemia of malignancy. ( Body, JJ, 2004)
"Hypercalcemia of malignancy (HCM) is a potentially life-threatening complication of cancer resulting from increased bone resorption by osteoclasts."2.41Treatment of hypercalcemia of malignancy with bisphosphonates. ( Berenson, JR, 2002)
"Specific treatment of cancer remains essential to prevent TIH relapse."2.41[Tumor-induced hypercalcemia. Review of bisphosphonate treatment]. ( Lortholary, A, 2001)
"Pamidronate (APD) is a potent inhibitor of bone resorption that is useful in the management of patients with osteolytic bone metastases from breast cancer or multiple myeloma, tumour-induced hypercalcaemia or Paget's disease of bone."2.40Pamidronate. A review of its use in the management of osteolytic bone metastases, tumour-induced hypercalcaemia and Paget's disease of bone. ( Coukell, AJ; Markham, A, 1998)
"Basic guidelines for cancer pain treatment can be found in many different handbooks published in the last years."2.40[Treatment of pain in oncology]. ( De Conno, F; Polastri, D, 1997)
"Treatment of cancer associated hypercalcaemia is based on an initial phase of volume repletion with isotonic saline, followed by drug treatment to inhibit bone resorption."2.39Pathogenesis and management of cancer associated hypercalcaemia. ( Ralston, SH, 1994)
"Haematologic malignancies and solid tumors are often complicated by the bone tissue destruction."2.39[Pharmacologic therapy of bone tissue changes due to hematologic malignancies and bone metastasis]. ( Kiełbiński, M, 1994)
"Main indications for BP treatment were breast cancer (36%), multiple myeloma (24%), prostate cancer (16%) and kidney cancer (4%)."1.42Risk factors influencing the duration of treatment with bisphosphonates until occurrence of an osteonecrosis of the jaw in 963 cancer patients. ( Felsenberg, D; Gabbert, TI; Hoffmeister, B, 2015)
"In this study, cancer patients who had received zoledronate exhibited a significant 30-fold increase in their risk to develop ONJ."1.35Zoledronate, smoking, and obesity are strong risk factors for osteonecrosis of the jaw: a case-control study. ( Dodson, TB; Wessel, JH; Zavras, AI, 2008)
"Pamidronate was well tolerated apart from one case of multifactorial renal failure."1.33Hypercalcemia and childhood cancer: a 7-year experience. ( Aerts, I; Chevret, L; Doz, F; Fattet, S; Garabedian, M; Kerdudo, C; Michon, J; Orbach, D; Pacquement, H, 2005)
"Pamidronate is a second-generation bisphosphonate that undergoes negligible biodegradation and is eliminated exclusively by renal excretions."1.30Pharmacokinetics of pamidronate disodium in patients with cancer with normal or impaired renal function. ( Berenson, JR; Knight, RD; Kowalski, MO; Lau, HS; Rosen, L; Seaman, JJ; Sioufi, A; Vescio, R; Woo, M, 1997)
"Breast cancers were more common in group N, squamous cell cancers predominated in group E (p < 0."1.29Parathyroid hormone-related protein and life expectancy in hypercalcemic cancer patients. ( Baumgartner, G; Blind, E; Pecherstorfer, M; Raue, F; Schilling, T; Ziegler, R; Zimmer-Roth, I, 1994)
" Patients received, on average, 30 mg less pamidronate than that given in the manufacturer's dosing schedule."1.29An audit of the management of malignant hypercalcaemia. ( Dodwell, DJ; Gerrard, GE; Overend, MA; Vail, A; Watters, J, 1996)
"In those patients in whom systemic anti-cancer therapy is available, treatment with APD improves survival, but in all other patients the primary aim of treatment should be symptom control."1.29Analysis of survival following treatment of tumour-induced hypercalcaemia with intravenous pamidronate (APD). ( A'Hern, RP; Hardy, JR; Ling, PJ, 1995)
"Pamidronate has been demonstrated to be an effective agent in the treatment of cancer-associated hypercalcaemia."1.28A comparison of low versus high dose pamidronate in cancer-associated hypercalcaemia. ( Boyle, IT; Cowan, RA; Dryburgh, FJ; Fraser, WD; Gallacher, SJ; Logue, FC; Ralston, SH, 1991)
"All three are useful for the treatment of hypercalcemia, but pamidronate seems to be the most effective."1.28Bisphosphonate treatment of bone metastases and hypercalcemia of malignancy. ( Coleman, RE, 1991)
"Life expectancy is poor in cancer-associated hypercalcemia even in patients who are actively treated."1.28Cancer-associated hypercalcemia: morbidity and mortality. Clinical experience in 126 treated patients. ( Boyle, IT; Campbell, J; Gallacher, SJ; Patel, U; Ralston, SH, 1990)
"There were seven patients with breast cancer, eight with lung cancer, and ten with a variety of other cancers."1.28Single high-dose (45 mg) infusions of aminohydroxypropylidene diphosphonate for severe malignant hypercalcemia. ( Cantwell, BM; Carmichael, J; Harris, AL; Mannix, KA, 1989)
"Eight patients with cancer associated hypercalcaemia were treated with the combination of aminohydroxypropylidene diphosphonate and salmon calcitonin for six days."1.27Treatment of cancer associated hypercalcaemia with combined aminohydroxypropylidene diphosphonate and calcitonin. ( Alzaid, AA; Boyle, IT; Gardner, MD; Ralston, SH, 1986)
" In order to establish a dose-response in humans, patients were divided into four groups receiving 30 mg, 45 mg, 60 mg, or 90 mg, respectively, as a 24-hour infusion."1.27Dose-response in the treatment of hypercalcemia of malignancy by a single infusion of the bisphosphonate AHPrBP. ( Burckhardt, P; Jacquet, AF; Jaeger, P; Thiébaud, D, 1988)
" AHPrBP was given as two-hour daily infusions for three days, and three different patients were treated at each of the six following dosage levels: 0."1.27Dose/response study of aminohydroxypropylidene bisphosphonate in tumor-associated hypercalcemia. ( Body, JJ; Borkowski, A; Klastersky, J; Pot, M; Sculier, JP, 1987)

Research

Studies (107)

TimeframeStudies, this research(%)All Research%
pre-199024 (22.43)18.7374
1990's47 (43.93)18.2507
2000's23 (21.50)29.6817
2010's11 (10.28)24.3611
2020's2 (1.87)2.80

Authors

AuthorsStudies
Walker, MD1
Shane, E1
Norman, SJ1
Reeves, DJ1
Saum, LM1
Owosho, AA1
Liang, STY1
Sax, AZ1
Wu, K1
Yom, SK1
Huryn, JM1
Estilo, CL1
Haykal, T1
Sundus, S1
Bachuwa, G1
Danish, R1
Gabbert, TI1
Hoffmeister, B1
Felsenberg, D1
Wang, Z1
Qiao, D1
Lu, Y1
Curtis, D1
Wen, X1
Yao, Y1
Zhao, H1
Wright, JD1
Tergas, AI1
Ananth, CV1
Burke, WM1
Hou, JY1
Chen, L1
Neugut, AI1
Richards, CA1
Hershman, DL1
O'Ryan, FS1
Khoury, S1
Liao, W1
Han, MM1
Hui, RL1
Baer, D1
Martin, D1
Liberty, D1
Lo, JC1
Weinstein, E1
Arnold, RM1
Nicolatou-Galitis, O1
Papadopoulou, E1
Sarri, T1
Boziari, P1
Karayianni, A1
Kyrtsonis, MC1
Repousis, P1
Barbounis, V1
Migliorati, CA1
Legrand, SB1
Goyne, H1
Stone, PJ1
Cannon, MJ1
Jacobsen, C1
Metzler, P1
Rössle, M1
Obwegeser, J1
Zemann, W1
Grätz, KW1
Thumbigere-Math, V1
Tu, L1
Huckabay, S1
Dudek, AZ1
Lunos, S1
Basi, DL1
Hughes, PJ1
Leach, JW1
Swenson, KK1
Gopalakrishnan, R1
Major, P2
Berenson, JR2
Pecherstorfer, M6
Steinhauer, EU1
Rizzoli, R2
Wetterwald, M1
Bergström, B1
Atula, ST1
Tähtelä, RK1
Nevalainen, JI1
Pylkkänen, LH1
Body, JJ9
Kerdudo, C2
Aerts, I2
Fattet, S2
Chevret, L2
Pacquement, H2
Doz, F2
Michon, J2
Garabedian, M2
Orbach, D2
Guarino, MJ1
Hill, CE1
Patel, K1
Zarychanski, R1
Elphee, E1
Walton, P1
Johnston, J1
Abu-Id, MH2
Açil, Y2
Gottschalk, J2
Kreusch, T2
Schivazappa, C1
Baldini, E1
Cortesi, E1
Dauria, G1
Roila, F1
Berto, P1
Shenker, NG1
Jawad, AS1
Warnke, PH1
Springer, I1
Wiltfang, J1
Russo, PA1
Wessel, JH1
Dodson, TB1
Zavras, AI1
Sleeboom, HP4
Bijvoet, OL4
van Oosterom, AT2
Gleed, JH1
O'Riordan, JL1
Mundy, GR2
Wilkinson, R1
Heath, DA2
van Breukelen, FJ1
Frijlink, WB1
Mulder, H1
Ling, PJ1
A'Hern, RP1
Hardy, JR1
Oiso, Y1
Tomita, A1
Hasegawa, H1
Ariyoshi, Y1
Niinomi, M1
Yamamoto, M1
Takano, T1
Sakiyama, N1
Anand, A1
Anand, N1
Walls, J1
Ratcliffe, WA1
Howell, A3
Bundred, NJ1
Budayr, AA1
Zysset, E1
Jenzer, A1
Thiébaud, D9
Ammann, P1
Jaquet-Müller, F1
Bonjour, JP1
Gertz, B1
Burckhardt, P7
Kiełbiński, M1
Gucalp, R2
Theriault, R1
Gill, I1
Madajewicz, S1
Chapman, R2
Navari, R1
Ahmann, F1
Zelenakas, K1
Heffernan, M1
Knight, RD2
Dumon, JC4
Gurney, H2
Grill, V2
Martin, TJ2
Wimalawansa, SJ1
Schilling, T2
Blind, E2
Zimmer-Roth, I2
Baumgartner, G1
Ziegler, R2
Raue, F2
Thirion, M1
Cleeren, A2
Redalieu, E1
Coleman, JM1
Chan, K1
Seaman, J2
Degen, PH1
Flesch, G1
Brox, A1
Batiste, G1
Nussbaum, SR1
Younger, J1
Vandepol, CJ1
Gagel, RF1
Zubler, MA1
Henderson, IC1
Mallette, LE2
Leidig, G1
Hall, TG1
Schaiff, RA1
Rosenmund, A1
Kinirons, MT1
Ralston, SH12
Gerrard, GE1
Dodwell, DJ2
Vail, A1
Watters, J1
Overend, MA1
Machado, CE1
Flombaum, CD1
Sauty, A1
Fioroni, P1
Juillerat, L1
Markert, M1
Ludwig, H1
Leuenberger, P1
MacConnachie, AM1
Rosen, L1
Vescio, R1
Lau, HS1
Woo, M1
Sioufi, A1
Kowalski, MO2
Seaman, JJ1
De Conno, F1
Polastri, D1
Young, G1
Shende, A1
Coukell, AJ1
Markham, A1
Tezer Kutluk, M1
Frye, D1
Paule, B1
Clerc, D1
Brion, N1
Louviaux, I1
Lortholary, A2
Hon, J1
Abdi, E1
Mills, G1
Menssen, HD1
Yunus, F1
Bell, R1
Body, J1
Quebe-Fehling, E1
Das, H1
Wang, L1
Kamath, A1
Bukowski, JF1
Kato, Y1
Tanaka, Y1
Miyagawa, F1
Yamashita, S1
Minato, N1
Santini, D1
Vincenzi, B1
Avvisati, G1
Dicuonzo, G1
Battistoni, F1
Gavasci, M1
Salerno, A1
Denaro, V1
Tonini, G1
Ostenstad, B1
Andersen, OK1
Gallacher, SJ7
Fraser, WD5
Logue, FC3
Dryburgh, FJ5
Cowan, RA5
Boyle, IT11
Morton, AR2
Daley-Yates, PT1
Hoggarth, CR1
Thürlimann, B1
Waldburger, R1
Senn, HJ1
Seraj, F2
Murray, RM1
Ho, PW1
Santamaria, JD1
Pitt, P1
Potts, C1
Jerums, G1
Ritch, P1
Wiernik, PH1
Sarma, PR1
Keller, A1
Richman, SP1
Tauer, K1
Neidhart, J1
Siegel, R1
Janisch, S1
Marosi, C1
Wogritsch, C1
Bosse, C1
Schratzberger, W1
Gerber, E1
Fortelny, A1
Lenzhofer, R1
Rainer, H1
Coleman, RE1
O'Reilly, DS1
Beastall, GH1
Patel, U3
Campbell, J1
Jacquet, AF4
Sawyer, N1
Newstead, C1
Drummond, A1
Cunningham, J1
Kefford, R1
Stuart-Harris, R1
Magritte, A1
Sculier, JP2
Borkowski, A2
Mannix, KA1
Carmichael, J1
Harris, AL2
Cantwell, BM2
Davis, JR1
Gardner, MD4
Jenkins, AS2
McKillop, JH1
Alzaid, AA2
Cantrill, JA1
Craig, AE1
Davies, M1
Anderson, DC1
Warrell, RP1
Harinck, HI1
Plantingh, AS1
Elte, JW1
Wildiers, J1
Neijt, JP1
Jaeger, P3
Pot, M1
Klastersky, J1
Portmann, L1
Fuss, M1
Karmali, R1
Gillet, C1
Corvilain, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer: A Non-inferiority, Randomized, Open, Parallel and Controlled Prospective Clinical Study[NCT02480634]Phase 4280 participants (Anticipated)Interventional2019-06-30Not yet recruiting
A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420]Phase 14 participants (Actual)Interventional2005-12-31Completed
Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation[NCT02074631]Phase 280 participants (Actual)Interventional2015-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

19 reviews available for pamidronate and Benign Neoplasms

ArticleYear
Hypercalcemia: A Review.
    JAMA, 2022, 10-25, Volume: 328, Issue:16

    Topics: Calcium; Coma; COVID-19; Dehydration; Denosumab; Humans; Hypercalcemia; Hyperparathyroidism, Primary

2022
Systematic literature review and network meta-analysis comparing bone-targeted agents for the prevention of skeletal-related events in cancer patients with bone metastasis.
    The oncologist, 2015, Volume: 20, Issue:4

    Topics: Bone Density Conservation Agents; Bone Diseases; Bone Neoplasms; Denosumab; Diphosphonates; Humans;

2015
Modern management of malignant hypercalcemia.
    The American journal of hospice & palliative care, 2011, Volume: 28, Issue:7

    Topics: Bone Density Conservation Agents; Calcitonin; Clinical Protocols; Diphosphonates; Fluid Therapy; Gal

2011
The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy.
    The oncologist, 2002, Volume: 7, Issue:6

    Topics: Anti-Inflammatory Agents; Bone Resorption; Diphosphonates; Dose-Response Relationship, Drug; Humans;

2002
Treatment of hypercalcemia of malignancy with bisphosphonates.
    Seminars in oncology, 2002, Volume: 29, Issue:6 Suppl 21

    Topics: Bone Resorption; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; H

2002
Hypercalcemia of malignancy.
    Seminars in nephrology, 2004, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Diphosphonates; Forecasting; Humans; Hypercalcemia; Imidazoles; Neoplasms; Pa

2004
[Bisphosphonate-associated osteonecrosis of the jaw].
    Mund-, Kiefer- und Gesichtschirurgie : MKG, 2006, Volume: 10, Issue:2

    Topics: Aged; Bone Density Conservation Agents; Clinical Trials as Topic; Diphosphonates; Female; Humans; Im

2006
[Pharmacologic therapy of bone tissue changes due to hematologic malignancies and bone metastasis].
    Acta haematologica Polonica, 1994, Volume: 25, Issue:2

    Topics: Bone Neoplasms; Calcitonin; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Neoplasms; Osteo

1994
Update on the medical treatment of hypercalcemia of malignancy.
    Clinical pharmacy, 1993, Volume: 12, Issue:2

    Topics: Animals; Antineoplastic Agents; Calcitonin; Diphosphonates; Etidronic Acid; Gallium; Humans; Hyperca

1993
[Hypercalcemia as an emergency].
    Schweizerische medizinische Wochenschrift, 1993, Apr-17, Volume: 123, Issue:15

    Topics: Calcitonin; Calcium; Diphosphonates; Emergencies; Fluid Therapy; Furosemide; Humans; Hypercalcemia;

1993
Newer agents for the treatment of malignant hypercalcemia.
    The American journal of the medical sciences, 1993, Volume: 305, Issue:6

    Topics: Diphosphonates; Etidronic Acid; Gallium; Humans; Hypercalcemia; Neoplasms; Pamidronate

1993
Pathogenesis and management of cancer associated hypercalcaemia.
    Cancer surveys, 1994, Volume: 21

    Topics: Antineoplastic Agents; Calcitonin; Calcium; Clodronic Acid; Diphosphonates; Diuretics; Etidronic Aci

1994
Pamidronate (Aredia, Ciba) in malignant hypercalcaemia.
    Intensive & critical care nursing, 1997, Volume: 13, Issue:1

    Topics: Diphosphonates; Drug Monitoring; Humans; Hypercalcemia; Neoplasms; Pamidronate

1997
[Treatment of pain in oncology].
    Tumori, 1997, Volume: 83, Issue:2 Suppl

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Dissociative; Diphosphonates; Fentanyl;

1997
Pamidronate. A review of its use in the management of osteolytic bone metastases, tumour-induced hypercalcaemia and Paget's disease of bone.
    Drugs & aging, 1998, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Diphosphonates; Humans; Hypercalcemia; Neopl

1998
Bisphosphonates as cancer drugs.
    Hospital practice (1995), 1999, May-15, Volume: 34, Issue:5

    Topics: Antineoplastic Agents; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Neoplasm Proteins; Ne

1999
Current and future directions in medical therapy: hypercalcemia.
    Cancer, 2000, Jun-15, Volume: 88, Issue:12 Suppl

    Topics: Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandronic Acid; Imidazoles; Neoplasms; Pamid

2000
Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Jan-15, Volume: 19, Issue:2

    Topics: Adult; Aged; Diphosphonates; Female; Humans; Hypercalcemia; Imidazoles; Male; Middle Aged; Neoplasms

2001
[Tumor-induced hypercalcemia. Review of bisphosphonate treatment].
    La Revue de medecine interne, 2001, Volume: 22, Issue:7

    Topics: Diagnosis, Differential; Diagnostic Errors; Diphosphonates; Etidronic Acid; Fluid Therapy; Hematolog

2001

Trials

27 trials available for pamidronate and Benign Neoplasms

ArticleYear
Efficacy and safety of ibandronate in the treatment of hypercalcemia of malignancy: a randomized multicentric comparison to pamidronate.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2003, Volume: 11, Issue:8

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Bone Resorption; Diphosphonates; Female; Human

2003
Clodronate as a single-dose intravenous infusion effectively provides short-term correction of malignant hypercalcemia.
    Acta oncologica (Stockholm, Sweden), 2003, Volume: 42, Issue:7

    Topics: Calcium; Clodronic Acid; Diphosphonates; Double-Blind Method; Female; Humans; Hypercalcemia; Infusio

2003
Comparison of intravenous (3-amino-1-hydroxypropylidene)-1, 1-bisphosphonate and volume repletion in tumour-induced hypercalcaemia.
    Lancet (London, England), 1983, Jul-30, Volume: 2, Issue:8344

    Topics: Adult; Aged; Calcium; Diphosphonates; Female; Fluid Therapy; Follow-Up Studies; Glomerular Filtratio

1983
Comparative study of available medical therapy for hypercalcemia of malignancy.
    The American journal of medicine, 1983, Volume: 74, Issue:3

    Topics: Administration, Oral; Adult; Aged; Calcium; Clinical Trials as Topic; Diphosphonates; Etidronic Acid

1983
Response to intravenous bisphosphonate therapy in hypercalcaemic patients with and without bone metastases: the role of parathyroid hormone-related protein.
    British journal of cancer, 1994, Volume: 70, Issue:1

    Topics: Bone Neoplasms; Calcium; Diphosphonates; Humans; Hypercalcemia; Infusions, Intravenous; Kidney Tubul

1994
Treatment of cancer-associated hypercalcemia. Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone.
    Archives of internal medicine, 1994, Sep-12, Volume: 154, Issue:17

    Topics: Adult; Breast Neoplasms; Calcium; Diphosphonates; Double-Blind Method; Drug Administration Schedule;

1994
Significance of plasma PTH-rp in patients with hypercalcemia of malignancy treated with bisphosphonate.
    Cancer, 1994, Apr-15, Volume: 73, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle

1994
Urinary excretion of aminohydroxypropylidene bisphosphonate in cancer patients after single intravenous infusions.
    Journal of pharmaceutical sciences, 1993, Volume: 82, Issue:6

    Topics: Adult; Aged; Bone Resorption; Chromatography, High Pressure Liquid; Diphosphonates; Female; Humans;

1993
Single-dose intravenous therapy with pamidronate for the treatment of hypercalcemia of malignancy: comparison of 30-, 60-, and 90-mg dosages.
    The American journal of medicine, 1993, Volume: 95, Issue:3

    Topics: Aged; Diphosphonates; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hyperca

1993
Interleukin-6 and tumor necrosis factor alpha levels after bisphosphonates treatment in vitro and in patients with malignancy.
    Bone, 1996, Volume: 18, Issue:2

    Topics: Aged; Aged, 80 and over; Bone Resorption; Clodronic Acid; Diphosphonates; Female; Follow-Up Studies;

1996
Decreased efficacy of bisphosphonates for recurrences of tumor-induced hypercalcemia.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2000, Volume: 8, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents; Breast Neoplasms; Diphosphonates; Female; Humans; Hypercalcem

2000
Pamidronate induces modifications of circulating angiogenetic factors in cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:5

    Topics: Aged; Angiogenesis Inducing Agents; Antineoplastic Agents; Cytokines; Diphosphonates; Endothelial Gr

2002
Disodium pamidronate versus mithramycin in the management of tumour-associated hypercalcemia.
    Acta oncologica (Stockholm, Sweden), 1992, Volume: 31, Issue:8

    Topics: Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate; Plicamycin

1992
Infusion rate and pharmacokinetics of intravenous pamidronate in the treatment of tumour-induced hypercalcaemia.
    Postgraduate medical journal, 1992, Volume: 68, Issue:800

    Topics: Adult; Aged; Aged, 80 and over; Diphosphonates; Drug Administration Schedule; Female; Humans; Hyperc

1992
Plicamycin and pamidronate in symptomatic tumor-related hypercalcemia: a prospective randomized crossover trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle Aged; Ne

1992
Comparative study of pamidronate disodium and etidronate disodium in the treatment of cancer-related hypercalcemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Calcium; Diphosphonates; Double-Blind Method; Etidronic Acid; Fem

1992
[Pamidronate in the treatment of tumor-associated hypercalcemia].
    Klinische Wochenschrift, 1991, Oct-02, Volume: 69, Issue:15

    Topics: Adult; Aged; Calcium; Diphosphonates; Female; Fluid Therapy; Humans; Hypercalcemia; Male; Middle Age

1991
Fast (4-h) or slow (24-h) infusions of pamidronate disodium (aminohydroxypropylidene diphosphonate (APD)) as single shot treatment of hypercalcaemia.
    Bone and mineral, 1990, Volume: 9, Issue:2

    Topics: Calcium; Creatinine; Diphosphonates; Humans; Hypercalcemia; Kinetics; Neoplasms; Pamidronate

1990
Comparison of three intravenous bisphosphonates in cancer-associated hypercalcaemia.
    Lancet (London, England), 1989, Nov-18, Volume: 2, Issue:8673

    Topics: Administration, Oral; Bone Resorption; Calcium; Clodronic Acid; Diphosphonates; Drug Administration

1989
Aminohydroxypropylidene bisphosphonate (APD) treatment for tumor-associated hypercalcemia: a randomized comparison between a 3-day treatment and single 24-hour infusions.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1989, Volume: 4, Issue:6

    Topics: Adult; Aged; Bone Resorption; Diphosphonates; Drug Administration Schedule; Female; Hematologic Test

1989
Comparison of different dose regimes of aminohydroxypropylidene-1,1-bisphosphonate (APD) in hypercalcaemia of malignancy.
    British journal of clinical pharmacology, 1989, Volume: 28, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Infusions, I

1989
Comparison of aminohydroxypropylidene diphosphonate, mithramycin, and corticosteroids/calcitonin in treatment of cancer-associated hypercalcaemia.
    Lancet (London, England), 1985, Oct-26, Volume: 2, Issue:8461

    Topics: Calcitonin; Calcium; Clinical Trials as Topic; Creatinine; Diphosphonates; Drug Therapy, Combination

1985
Effect of single high dose infusions of aminohydroxypropylidene diphosphonate on hypercalcaemia caused by cancer.
    British medical journal (Clinical research ed.), 1987, Feb-21, Volume: 294, Issue:6570

    Topics: Adult; Aged; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle Aged; Neoplasms; Pamidronat

1987
Single dose versus daily intravenous aminohydroxypropylidene biphosphonate (APD) for the hypercalcaemia of malignancy.
    British medical journal (Clinical research ed.), 1988, Mar-19, Volume: 296, Issue:6625

    Topics: Calcium; Diphosphonates; Drug Administration Schedule; Female; Humans; Hypercalcemia; Infusions, Int

1988
Treatment of hypercalcaemia of malignancy.
    British medical journal (Clinical research ed.), 1988, May-21, Volume: 296, Issue:6634

    Topics: Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate

1988
Questions about clinical trials in hypercalcemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:5

    Topics: Clinical Trials as Topic; Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate

1988
Role of bone and kidney in tumor-induced hypercalcemia and its treatment with bisphosphonate and sodium chloride.
    The American journal of medicine, 1987, Volume: 82, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bone Resorption; Calcium; Clinical Trials as Topic; Diphosphonates;

1987

Other Studies

61 other studies available for pamidronate and Benign Neoplasms

ArticleYear
Use of Pamidronate for Hypercalcemia of Malignancy in Renal Dysfunction.
    Journal of pharmacy practice, 2021, Volume: 34, Issue:4

    Topics: Acute Kidney Injury; Diphosphonates; Humans; Hypercalcemia; Indiana; Neoplasms; Pamidronate; Retrosp

2021
Medication-related osteonecrosis of the jaw: An update on the memorial sloan kettering cancer center experience and the role of premedication dental evaluation in prevention.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2018, Volume: 125, Issue:5

    Topics: Adult; Aged; Angiogenesis Inhibitors; Bevacizumab; Bisphosphonate-Associated Osteonecrosis of the Ja

2018
Primary isolated hepatosplenic sarcoidosis mimicking malignancy and causing symptomatic hypercalcaemia.
    BMJ case reports, 2019, Jan-22, Volume: 12, Issue:1

    Topics: Aftercare; Aged; Bone Density Conservation Agents; Diagnosis, Differential; Female; Humans; Hypercal

2019
Risk factors influencing the duration of treatment with bisphosphonates until occurrence of an osteonecrosis of the jaw in 963 cancer patients.
    Journal of cancer research and clinical oncology, 2015, Volume: 141, Issue:4

    Topics: Aged; Bone Density Conservation Agents; Breast Neoplasms; Diphosphonates; Disease-Free Survival; Fem

2015
Quality and Outcomes of Treatment of Hypercalcemia of Malignancy.
    Cancer investigation, 2015, Volume: 33, Issue:8

    Topics: Aged; Bone Neoplasms; Calcitonin; Diphosphonates; Diuretics; Female; Glucocorticoids; Humans; Hyperc

2015
Intravenous bisphosphonate-related osteonecrosis of the jaw: bone scintigraphy as an early indicator.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:7

    Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Diphosphonates; Early Diagnosis

2009
Bisphosphonates for bone pain #113.
    Journal of palliative medicine, 2010, Volume: 13, Issue:7

    Topics: Bone Density Conservation Agents; Bone Neoplasms; Diphosphonates; Female; Humans; Imidazoles; Neopla

2010
Osteonecrosis of the jaw in oncology patients treated with bisphosphonates: prospective experience of a dental oncology referral center.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2011, Volume: 112, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bone Density Co

2011
Combinatorial strategies for alleviation of tumor-associated immune suppression and therapeutic vaccination against ovarian cancer.
    Immunotherapy, 2011, Volume: 3, Issue:7

    Topics: Adjuvants, Immunologic; Antineoplastic Agents, Alkylating; B7-H1 Antigen; Cancer Vaccines; Clonal An

2011
Osteopathology induced by bisphosphonates and dental implants: clinical observations.
    Clinical oral investigations, 2013, Volume: 17, Issue:1

    Topics: Actinomycosis; Administration, Intravenous; Administration, Oral; Alendronate; Anti-Bacterial Agents

2013
A retrospective study evaluating frequency and risk factors of osteonecrosis of the jaw in 576 cancer patients receiving intravenous bisphosphonates.
    American journal of clinical oncology, 2012, Volume: 35, Issue:4

    Topics: Bone Density Conservation Agents; Diphosphonates; Female; Humans; Imidazoles; Incidence; Injections,

2012
Hypercalcemia and childhood cancer: a 7-year experience.
    Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Diphosphonates; Female; Humans; Hypercal

2005
[Hypercalcemia and childhood cancer].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Diphosphonates; Female; Humans; Hypercal

2005
Bisphosphonates, cancer, and osteonecrosis--a single practice experience.
    Delaware medical journal, 2005, Volume: 77, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2005
Osteonecrosis of the jaw associated with pamidronate therapy.
    American journal of hematology, 2006, Volume: 81, Issue:1

    Topics: Actinomycosis; Antineoplastic Agents; Diphosphonates; Female; Humans; Male; Mandible; Neoplasms; Ost

2006
[Cost analysis of tumor-induced osteolysis treated with intravenous zoledronic acid and pamidronate: a time-motion study].
    Recenti progressi in medicina, 2007, Volume: 98, Issue:1

    Topics: Bone Density Conservation Agents; Costs and Cost Analysis; Diphosphonates; Humans; Imidazoles; Infus

2007
Bisphosphonates and osteonecrosis of the jaw.
    Rheumatology (Oxford, England), 2007, Volume: 46, Issue:7

    Topics: Bone Remodeling; Diphosphonates; Humans; Imidazoles; Jaw Diseases; Neoplasms; Osteonecrosis; Osteopo

2007
"Bis-phossy jaws" - high and low risk factors for bisphosphonate-induced osteonecrosis of the jaw.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2008, Volume: 36, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bone Density Conservation Agents; Diphosphona

2008
Zoledronate, smoking, and obesity are strong risk factors for osteonecrosis of the jaw: a case-control study.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008, Volume: 66, Issue:4

    Topics: Age Factors; Aged; Antineoplastic Agents; Bone Density Conservation Agents; Case-Control Studies; Co

2008
Hypercalcaemia due to malignancy. Role of the kidney and treatment.
    Contributions to nephrology, 1982, Volume: 33

    Topics: Calcitonin; Calcium; Diphosphonates; Extracellular Space; Fluid Therapy; Glomerular Filtration Rate;

1982
Efficacy of amino-hydroxypropylidene bisphosphonate in hypercalcemia: observations on regulation of serum calcium.
    Calcified tissue international, 1982, Volume: 34, Issue:4

    Topics: Adult; Aged; Bone Resorption; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyro

1982
Analysis of survival following treatment of tumour-induced hypercalcaemia with intravenous pamidronate (APD).
    British journal of cancer, 1995, Volume: 72, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle Aged; Ne

1995
Pamidronate treatment in patients with tumor-associated hypercalcemia: pharmacological effects and pharmacokinetics.
    Endocrine journal, 1994, Volume: 41, Issue:6

    Topics: Aged; Calcium; Diphosphonates; Female; Homeostasis; Humans; Hypercalcemia; Infusions, Intravenous; K

1994
Pamidronate for cancer-associated hypercalcemia.
    Archives of internal medicine, 1995, Mar-27, Volume: 155, Issue:6

    Topics: Diphosphonates; Drug Administration Schedule; Humans; Hypercalcemia; Neoplasms; Pamidronate

1995
Effects of treatment of malignancy-associated hypercalcemia on serum parathyroid hormone-related protein.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:4

    Topics: Alendronate; Calcitriol; Calcium; Creatinine; Diphosphonates; Female; Humans; Hypercalcemia; Male; N

1994
Treatment of tumour-induced hypercalcaemia with the bisphosphonate pamidronate: dose-response relationship and influence of tumour type.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Calcium; Diphosphonates; Dose-Response Relationship,

1994
Parathyroid hormone-related protein and response to pamidronate in tumour-induced hypercalcaemia.
    Lancet (London, England), 1993, Jun-26, Volume: 341, Issue:8861

    Topics: Bone Neoplasms; Calcium; Cyclic AMP; Diphosphonates; Electrolytes; Humans; Hypercalcemia; Kidney Tub

1993
Parathyroid hormone-related protein and life expectancy in hypercalcemic cancer patients.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Diphosphonates; Female; Humans; Hypercalcemia

1994
Circulating PTHrP concentrations in tumor-induced hypercalcemia: influence on the response to bisphosphonate and changes after therapy.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:6

    Topics: Adult; Aged; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle Aged; Neoplasms; P

1993
Parathyroid hormone-related protein (PTHrP) does not regulate 1,25-dihydroxyvitamin D serum levels in hypercalcemia of malignancy.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:3

    Topics: Adult; Aged; Dihydroxycholecalciferols; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle

1993
An audit of the management of malignant hypercalcaemia.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1996, Volume: 8, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Clinical Protocols; Diphosphonates; Female; Follow-Up Studi

1996
Safety of pamidronate in patients with renal failure and hypercalcemia.
    Clinical nephrology, 1996, Volume: 45, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Creatinine; Diphosphonates; Female; Follow-Up Studies; Huma

1996
Pharmacokinetics of pamidronate disodium in patients with cancer with normal or impaired renal function.
    Journal of clinical pharmacology, 1997, Volume: 37, Issue:4

    Topics: Aged; Aged, 80 and over; Area Under Curve; Diphosphonates; Female; Fever; Headache; Humans; Male; Me

1997
Use of pamidronate in the management of acute cancer-related hypercalcemia in children.
    Medical and pediatric oncology, 1998, Volume: 30, Issue:2

    Topics: Acute Disease; Adolescent; Calcium; Child; Child, Preschool; Diphosphonates; Female; Humans; Hyperca

1998
Use of bisphosphonates in hypercalcemia associated with childhood cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:6

    Topics: Antineoplastic Agents; Child; Diphosphonates; Dose-Response Relationship, Drug; Humans; Hypercalcemi

1999
Readers question whether drug increases side effects of chemotherapy.
    Clinical journal of oncology nursing, 1999, Volume: 3, Issue:3

    Topics: Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Diphosphonates; Drug Monitoring; D

1999
[Biosphonates in oncology].
    Presse medicale (Paris, France : 1983), 2000, Apr-08, Volume: 29, Issue:13

    Topics: Bone Neoplasms; Clodronic Acid; Diphosphonates; Fractures, Bone; Humans; Neoplasms; Osteolysis; Pain

2000
Vgamma2Vdelta2 T-cell receptor-mediated recognition of aminobisphosphonates.
    Blood, 2001, Sep-01, Volume: 98, Issue:5

    Topics: Alendronate; Antigens; Cell Line, Transformed; Cytotoxicity, Immunologic; Diphosphonates; Etidronic

2001
Targeting of tumor cells for human gammadelta T cells by nonpeptide antigens.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Nov-01, Volume: 167, Issue:9

    Topics: Cytotoxicity, Immunologic; Diphosphates; Diphosphonates; Humans; Immunotherapy; Interferon-gamma; Ly

2001
Factors predicting the acute effect of pamidronate on serum calcium in hypercalcemia of malignancy.
    Calcified tissue international, 1992, Volume: 51, Issue:6

    Topics: Absorption; Calcium; Cyclic AMP; Diphosphonates; Humans; Hypercalcemia; Infusions, Intravenous; Kidn

1992
Treatment of resistant tumor-induced hypercalcemia with escalating doses of pamidronate (APD).
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:8

    Topics: Bone Resorption; Diphosphonates; Drug Resistance; Female; Humans; Hypercalcemia; Middle Aged; Neopla

1992
Recovery of parathyroid hormone secretion during correction of tumor-associated hypercalcemia.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:6

    Topics: Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Male; Middle Aged; Neoplasms; Pamidronate; P

1992
Circulating PTH and PTHrP levels before and after treatment of tumor induced hypercalcemia with Pamidronate Disodium (APD).
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:6

    Topics: Calcium; Diphosphonates; Humans; Hypercalcemia; Neoplasm Proteins; Neoplasms; Pamidronate; Parathyro

1992
Pamidronate.
    The Medical letter on drugs and therapeutics, 1992, Jan-10, Volume: 34, Issue:861

    Topics: Clinical Trials as Topic; Diphosphonates; Humans; Hypercalcemia; Hyperparathyroidism; Neoplasms; Ost

1992
A comparison of low versus high dose pamidronate in cancer-associated hypercalcaemia.
    Bone and mineral, 1991, Volume: 15, Issue:3

    Topics: Calcium; Creatinine; Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate

1991
Bisphosphonate treatment of bone metastases and hypercalcemia of malignancy.
    Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:8

    Topics: Animals; Bone and Bones; Bone Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hyp

1991
Direct and indirect assessment of the parathyroid hormone response to pamidronate therapy in Paget's disease of bone and hypercalcaemia of malignancy.
    Bone and mineral, 1991, Volume: 12, Issue:2

    Topics: Aged; Calcium; Cyclic AMP; Diphosphonates; Female; Glomerular Filtration Rate; Humans; Hypercalcemia

1991
Use of bisphosphonates in hypercalcaemia due to malignancy.
    Lancet (London, England), 1990, Mar-24, Volume: 335, Issue:8691

    Topics: Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate

1990
Cancer-associated hypercalcemia: morbidity and mortality. Clinical experience in 126 treated patients.
    Annals of internal medicine, 1990, Apr-01, Volume: 112, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Calcitonin; Diphosphonates; Dru

1990
Fast and effective treatment of malignant hypercalcemia. Combination of suppositories of calcitonin and a single infusion of 3-amino 1-hydroxypropylidene-1-bisphosphonate.
    Archives of internal medicine, 1990, Volume: 150, Issue:10

    Topics: Aged; Calcitonin; Diphosphonates; Drug Therapy, Combination; Female; Fluid Therapy; Humans; Hypercal

1990
Renal phosphate threshold and response to pamidronate in humoral hypercalcaemia of malignancy.
    Lancet (London, England), 1989, Jul-29, Volume: 2, Issue:8657

    Topics: Bone Neoplasms; Diphosphonates; Humans; Hypercalcemia; Infusions, Intravenous; Kidney; Neoplasms; Pa

1989
Single high-dose (45 mg) infusions of aminohydroxypropylidene diphosphonate for severe malignant hypercalcemia.
    Cancer, 1989, Sep-15, Volume: 64, Issue:6

    Topics: Adult; Aged; Diphosphonates; Female; Follow-Up Studies; Humans; Hypercalcemia; Hypocalcemia; Infusio

1989
Malignancy-associated hypercalcaemia: relationship between mechanisms of hypercalcaemia and response to antihypercalcaemic therapy.
    Bone and mineral, 1987, Volume: 2, Issue:3

    Topics: Calcitonin; Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate; Plicamycin

1987
Treatment of cancer associated hypercalcaemia with combined aminohydroxypropylidene diphosphonate and calcitonin.
    British medical journal (Clinical research ed.), 1986, Jun-14, Volume: 292, Issue:6535

    Topics: Bone Resorption; Calcitonin; Calcium; Creatinine; Diphosphonates; Drug Therapy, Combination; Humans;

1986
Dose-dependent effect of AHPrBP in malignant hypercalcemia: wishful thinking and facts.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:10

    Topics: Diphosphonates; Dose-Response Relationship, Drug; Humans; Hypercalcemia; Neoplasms; Pamidronate

1988
Clinical experience with aminohydroxypropylidene bisphosphonate (APD) in the management of cancer-associated hypercalcaemia.
    The Quarterly journal of medicine, 1988, Volume: 68, Issue:258

    Topics: Diphosphonates; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hype

1988
Dose-response in the treatment of hypercalcemia of malignancy by a single infusion of the bisphosphonate AHPrBP.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Creatinine; Diphosphonates; Dose-Response Relationship, Dru

1988
A single-day treatment of tumor-induced hypercalcemia by intravenous amino-hydroxypropylidene bisphosphonate.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1986, Volume: 1, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Infusions, I

1986
Dose/response study of aminohydroxypropylidene bisphosphonate in tumor-associated hypercalcemia.
    The American journal of medicine, 1987, Volume: 82, Issue:5

    Topics: Adult; Aged; Diphosphonates; Dose-Response Relationship, Drug; Female; Humans; Hypercalcemia; Male;

1987
Oral versus intravenous AHPrBP (APD) in the treatment of hypercalcemia of malignancy.
    Bone, 1986, Volume: 7, Issue:4

    Topics: Administration, Oral; Aged; Diphosphonates; Female; Humans; Hypercalcemia; Infusions, Parenteral; Ma

1986
[Treatment of hypercalcemia].
    Revue medicale de Bruxelles, 1986, Volume: 7, Issue:1

    Topics: Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate

1986