Page last updated: 2024-10-19

palmitic acid and Necrosis

palmitic acid has been researched along with Necrosis in 15 studies

Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
" Palmitic acid (PA)-overload was used to assess lipotoxicity-induced necrosis."4.12The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2. ( Cao, X; Carver, W; Cui, T; Gao, C; Kiaris, H; Nguyen, V; Tan, W; Tian, Y; Zhang, Y, 2022)
" The toxic effects of DG are linked to glucose metabolism and require a functional Rim101 signaling cascade involving the Rim21-dependent sensing complex and the activation of a calpain-like protease."1.48Diacylglycerol triggers Rim101 pathway-dependent necrosis in yeast: a model for lipotoxicity. ( Bashir, M; Büttner, S; Carmona-Gutierrez, D; Diessl, J; Eisenberg, T; Foessl, I; Franz, J; Gourlay, CW; Graier, WF; Khan, MJ; Knittelfelder, O; Kohlwein, SD; Kroemer, G; Kühnlein, RP; Madeo, F; Ring, J; Rockenfeller, P; Rost, R; Schmiedhofer, V; Sigrist, SJ; Smolnig, M; Zimmermann, A, 2018)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's6 (40.00)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Nguyen, V1
Zhang, Y1
Gao, C1
Cao, X1
Tian, Y1
Carver, W1
Kiaris, H1
Cui, T1
Tan, W1
Dauda, WP1
Singh Rana, V1
Solanke, AU1
Krishnan, G1
Bashya, BM1
Aggarwal, R1
Shanmugam, V1
Gezginci-Oktayoglu, S1
Sancar, S1
Karatug-Kacar, A1
Bolkent, S1
Rockenfeller, P2
Smolnig, M1
Diessl, J1
Bashir, M1
Schmiedhofer, V1
Knittelfelder, O1
Ring, J1
Franz, J1
Foessl, I1
Khan, MJ2
Rost, R1
Graier, WF2
Kroemer, G1
Zimmermann, A1
Carmona-Gutierrez, D1
Eisenberg, T1
Büttner, S1
Sigrist, SJ1
Kühnlein, RP1
Kohlwein, SD1
Gourlay, CW1
Madeo, F2
Kim, SK3
Oh, E2
Yun, M2
Lee, SB3
Chae, GT2
Moravcová, A1
Červinková, Z1
Kučera, O1
Mezera, V1
Rychtrmoc, D1
Lotková, H1
Seo, G2
Lee, JY1
Rizwan Alam, M1
Waldeck-Weiermair, M1
Karsten, F1
Groschner, L1
Riederer, M1
Hallström, S1
Konya, V1
Heinemann, A1
Malli, R1
Jin, SH1
Jiang, YZ1
Xue, YM1
Deng, Y1
Zhu, ZY1
BUCHANAN, KD1
MACGREGOR, RF1
Aronis, A1
Madar, Z1
Tirosh, O1
Kong, JY1
Rabkin, SW1
Le Dinh, T1
Freneaux, E1
Labbe, G1
Letteron, P1
Degott, C1
Geneve, J1
Berson, A1
Larrey, D1
Pessayre, D1
Farghali, H1
Machková, J1
Julis, I1
Buchar, E1
Janků, I1
Masek, K1

Other Studies

15 other studies available for palmitic acid and Necrosis

ArticleYear
The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2.
    Cells, 2022, 06-14, Volume: 11, Issue:12

    Topics: COVID-19; HEK293 Cells; Humans; Lipid Metabolism; Necrosis; NF-E2-Related Factor 2; Palmitic Acid; S

2022
Metabolomic analysis of sheath blight disease of rice (Oryza sativa L.) induced by Rhizoctonia solani phytotoxin.
    Journal of applied microbiology, 2022, Volume: 133, Issue:5

    Topics: Necrosis; Oryza; Palmitic Acid; Plant Diseases; Rhizoctonia; Virulence Factors; Water

2022
miR-375 induces adipogenesis through targeting Erk1 in pancreatic duct cells under the influence of sodium palmitate.
    Journal of cellular physiology, 2021, Volume: 236, Issue:5

    Topics: Adipogenesis; Animals; Cell Death; Cell Differentiation; Cell Line; Cell Proliferation; Glucose; Ins

2021
Diacylglycerol triggers Rim101 pathway-dependent necrosis in yeast: a model for lipotoxicity.
    Cell death and differentiation, 2018, Volume: 25, Issue:4

    Topics: Animals; Diglycerides; Drosophila melanogaster; Endothelial Cells; Humans; Models, Biological; Necro

2018
Palmitate induces cisternal ER expansion via the activation of XBP-1/CCTα-mediated phospholipid accumulation in RAW 264.7 cells.
    Lipids in health and disease, 2015, Jul-16, Volume: 14

    Topics: Animals; Choline-Phosphate Cytidylyltransferase; DNA-Binding Proteins; Down-Regulation; Endoplasmic

2015
The effect of oleic and palmitic acid on induction of steatosis and cytotoxicity on rat hepatocytes in primary culture.
    Physiological research, 2015, Volume: 64, Issue:Suppl 5

    Topics: Albumins; Animals; Apoptosis; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Hepa

2015
Palmitate induces RIP1/RIP3-dependent necrosis via MLKL-mediated pore formation in the plasma membrane of RAW 264.7 cells.
    Biochemical and biophysical research communications, 2017, Jan-08, Volume: 482, Issue:2

    Topics: Animals; Cell Membrane; Cell Membrane Permeability; GTPase-Activating Proteins; Mice; Necrosis; Palm

2017
Inhibition of autophagy rescues palmitic acid-induced necroptosis of endothelial cells.
    The Journal of biological chemistry, 2012, Jun-15, Volume: 287, Issue:25

    Topics: Autophagy; Autophagy-Related Protein 7; Calcium Signaling; Cells, Cultured; Chelating Agents; Class

2012
Palmitate induces RIP1-dependent necrosis in RAW 264.7 cells.
    Atherosclerosis, 2012, Volume: 225, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Cell Line; Cell Shape; Cell Survival; Cyclic N-Oxides; Dose-Respon

2012
[Apoptosis-inducing effect of palmitic acids on rat pancreatic islet cells in primary culture: a preliminary study].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:5

    Topics: Animals; Apoptosis; Cells, Cultured; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; In

2003
PROLONGATION OF THE SURVIVAL OF HUMAN RED CELLS IN MICE BY "CHEMICAL SPLENECTOMY".
    British journal of experimental pathology, 1964, Volume: 45

    Topics: Chromium Isotopes; Erythrocytes; Hemoglobins; Liver; Mice; Necrosis; Palmitic Acid; Pathology; Pharm

1964
Lipotoxic effects of triacylglycerols in J774.2 macrophages.
    Nutrition (Burbank, Los Angeles County, Calif.), 2008, Volume: 24, Issue:2

    Topics: Animals; Cell Cycle; Cell Death; Cell Line; DNA; Linoleic Acid; Macrophages; Mice; Necrosis; Oleic A

2008
Palmitate-induced apoptosis in cardiomyocytes is mediated through alterations in mitochondria: prevention by cyclosporin A.
    Biochimica et biophysica acta, 2000, May-06, Volume: 1485, Issue:1

    Topics: Animals; Apoptosis; Cell Nucleus; Cell Survival; Cells, Cultured; Chick Embryo; Cyclosporine; Cytoch

2000
Amineptine, a tricyclic antidepressant, inhibits the mitochondrial oxidation of fatty acids and produces microvesicular steatosis of the liver in mice.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Antidepressive Agents, Tricyclic; Breath Tests; Chemical and Drug Induce

1988
Possible effects of muramyl dipeptide on liver cell membranes.
    Methods and findings in experimental and clinical pharmacology, 1986, Volume: 8, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Carbon Tetrachloride; Cell Membrane; Cell Survival; Hist

1986