palmitic acid has been researched along with Hyperinsulinism in 14 studies
Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aging rats showed hyperinsulinemia and hyperlipidemia, and insulin resistance as examined by the decreased glucose decay constant rate during insulin tolerance test (kITT)." | 5.39 | Genipin ameliorates age-related insulin resistance through inhibiting hepatic oxidative stress and mitochondrial dysfunction. ( Cai, L; Feng, H; Gong, D; Guan, L; Wu, Q; Yang, M; Yuan, B; Zhao, J; Zhao, X; Zou, Y, 2013) |
| "Obesity impairs cognition, and the leptin-induced increase of brain-derived neurotrophic factor (BDNF) and neurogenesis." | 3.81 | Teasaponin improves leptin sensitivity in the prefrontal cortex of obese mice. ( Huang, XF; Szabo, A; Wang, Q; Wang, S; Wu, Y; Yu, S; Yu, Y, 2015) |
| "The aging rats showed hyperinsulinemia and hyperlipidemia, and insulin resistance as examined by the decreased glucose decay constant rate during insulin tolerance test (kITT)." | 1.39 | Genipin ameliorates age-related insulin resistance through inhibiting hepatic oxidative stress and mitochondrial dysfunction. ( Cai, L; Feng, H; Gong, D; Guan, L; Wu, Q; Yang, M; Yuan, B; Zhao, J; Zhao, X; Zou, Y, 2013) |
| "Skeletal muscle insulin resistance is associated with lipid accumulation, but whether insulin resistance is due to reduced or enhanced flux of long-chain fatty acids into the mitochondria is both controversial and unclear." | 1.35 | Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance. ( Allen, TL; Bruce, CR; Carpenter, K; Cooney, GJ; Febbraio, MA; Hoy, AJ; Kraegen, EW; Turner, N; Watt, MJ, 2009) |
| "We hypothesised that in subjects with type 2 diabetes muscle malonyl-CoA (an inhibitor of fatty acid oxidation) would be elevated at baseline in comparison with control subjects and in particular during physiological hyperinsulinaemia with hyperglycaemia." | 1.33 | Dysregulation of muscle fatty acid metabolism in type 2 diabetes is independent of malonyl-CoA. ( Bell, JA; Cadenas, JG; Fujita, S; Rasmussen, BB; Volpi, E, 2006) |
| "Despite hyperinsulinemia, the amount of glucose infused was lower in the Lard compared with the Low-Fat group." | 1.31 | The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats. ( Dobbins, RL; Giacca, A; McGarry, JD; Myhill, J; Szczepaniak, LS; Tamura, Y; Uchino, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mazibuko, SE | 1 |
| Muller, CJ | 1 |
| Joubert, E | 1 |
| de Beer, D | 1 |
| Johnson, R | 1 |
| Opoku, AR | 1 |
| Louw, J | 1 |
| Kanaley, JA | 1 |
| Shadid, S | 1 |
| Sheehan, MT | 1 |
| Guo, Z | 1 |
| Jensen, MD | 1 |
| Guan, L | 1 |
| Feng, H | 1 |
| Gong, D | 1 |
| Zhao, X | 1 |
| Cai, L | 1 |
| Wu, Q | 1 |
| Yuan, B | 1 |
| Yang, M | 1 |
| Zhao, J | 1 |
| Zou, Y | 1 |
| Li, Y | 1 |
| Lu, Z | 1 |
| Zhang, X | 1 |
| Yu, H | 1 |
| Kirkwood, KL | 1 |
| Lopes-Virella, MF | 1 |
| Huang, Y | 1 |
| Yu, Y | 1 |
| Wu, Y | 1 |
| Szabo, A | 1 |
| Wang, S | 1 |
| Yu, S | 1 |
| Wang, Q | 1 |
| Huang, XF | 1 |
| Titov, VN | 1 |
| Shoibonov, BB | 1 |
| Fabbrini, E | 1 |
| deHaseth, D | 1 |
| Deivanayagam, S | 1 |
| Mohammed, BS | 1 |
| Vitola, BE | 1 |
| Klein, S | 1 |
| Bruce, CR | 1 |
| Hoy, AJ | 1 |
| Turner, N | 1 |
| Watt, MJ | 1 |
| Allen, TL | 1 |
| Carpenter, K | 1 |
| Cooney, GJ | 1 |
| Febbraio, MA | 1 |
| Kraegen, EW | 1 |
| Iozzo, P | 1 |
| Bucci, M | 1 |
| Roivainen, A | 1 |
| Någren, K | 1 |
| Järvisalo, MJ | 1 |
| Kiss, J | 1 |
| Guiducci, L | 1 |
| Fielding, B | 1 |
| Naum, AG | 1 |
| Borra, R | 1 |
| Virtanen, K | 1 |
| Savunen, T | 1 |
| Salvadori, PA | 1 |
| Ferrannini, E | 1 |
| Knuuti, J | 1 |
| Nuutila, P | 1 |
| Bernardi, S | 1 |
| Zauli, G | 1 |
| Tikellis, C | 1 |
| Candido, R | 1 |
| Fabris, B | 1 |
| Secchiero, P | 1 |
| Cooper, ME | 1 |
| Thomas, MC | 1 |
| Bell, JA | 1 |
| Volpi, E | 1 |
| Fujita, S | 1 |
| Cadenas, JG | 1 |
| Rasmussen, BB | 1 |
| Morris, RT | 1 |
| Laye, MJ | 1 |
| Lees, SJ | 1 |
| Rector, RS | 1 |
| Thyfault, JP | 1 |
| Booth, FW | 1 |
| Guerre-Millo, M | 1 |
| Rouault, C | 1 |
| Poulain, P | 1 |
| André, J | 1 |
| Poitout, V | 1 |
| Peters, JM | 1 |
| Gonzalez, FJ | 1 |
| Fruchart, JC | 1 |
| Reach, G | 1 |
| Staels, B | 1 |
| Dobbins, RL | 1 |
| Szczepaniak, LS | 1 |
| Myhill, J | 1 |
| Tamura, Y | 1 |
| Uchino, H | 1 |
| Giacca, A | 1 |
| McGarry, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Insulin and Sarcopenia in the Elderly[NCT00690534] | Phase 1 | 88 participants (Actual) | Interventional | 2005-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 other studies available for palmitic acid and Hyperinsulinism
| Article | Year |
|---|---|
Amelioration of palmitate-induced insulin resistance in C₂C₁₂ muscle cells by rooibos (Aspalathus linearis).
Topics: Animals; Aspalathus; Cell Line; Hyperinsulinism; Insulin Resistance; Mice; Muscle, Skeletal; Palmiti | 2013 |
Hyperinsulinemia and skeletal muscle fatty acid trafficking.
Topics: Adult; Carbon Radioisotopes; Carnitine; Cohort Studies; Down-Regulation; Fatty Acids, Nonesterified; | 2013 |
Genipin ameliorates age-related insulin resistance through inhibiting hepatic oxidative stress and mitochondrial dysfunction.
Topics: Adenosine Triphosphate; Age Factors; Aging; Animals; Antioxidants; Cell Line; Dose-Response Relation | 2013 |
Metabolic syndrome exacerbates inflammation and bone loss in periodontitis.
Topics: Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Animals; Chemokine CCL2; Cytokines; Diet, | 2015 |
Teasaponin improves leptin sensitivity in the prefrontal cortex of obese mice.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Diet, High-Fat; Hyperinsulinism; Insuli | 2015 |
[THE UNESTERIFIED FATTY ACIDS IN BLOOD PLASMA AND INTERCELLULAR MEDIUM: EFFECT OF INSULIN AND ALBUMIN (THE LECTURE)].
Topics: Adenosine Triphosphate; Adipose Tissue; Biological Transport; Fatty Acids, Nonesterified; Glucose; H | 2016 |
Alterations in fatty acid kinetics in obese adolescents with increased intrahepatic triglyceride content.
Topics: Abdomen; Adipose Tissue; Adolescent; Body Composition; Body Mass Index; Fatty Liver; Female; Glucose | 2009 |
Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance.
Topics: Animals; Carnitine O-Palmitoyltransferase; Dietary Fats; Electroporation; Fatty Acids; Glucose Clamp | 2009 |
Fatty acid metabolism in the liver, measured by positron emission tomography, is increased in obese individuals.
Topics: Animals; Carbon Radioisotopes; Case-Control Studies; Disease Models, Animal; Fasting; Fatty Acids; H | 2010 |
TNF-related apoptosis-inducing ligand significantly attenuates metabolic abnormalities in high-fat-fed mice reducing adiposity and systemic inflammation.
Topics: Adiposity; Animals; Apoptosis; Calorimetry; Cytokines; Dietary Fats; Energy Intake; Glucose Toleranc | 2012 |
Dysregulation of muscle fatty acid metabolism in type 2 diabetes is independent of malonyl-CoA.
Topics: Adult; Blood Glucose; Carbon Isotopes; Case-Control Studies; Diabetes Mellitus, Type 2; Fatty Acids; | 2006 |
Exercise-induced attenuation of obesity, hyperinsulinemia, and skeletal muscle lipid peroxidation in the OLETF rat.
Topics: Adipose Tissue; Aging; Aldehydes; Animals; Blood Glucose; Disease Models, Animal; Eating; Glutathion | 2008 |
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Dietary Fats; Drug Synergism; Fastin | 2001 |
The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats.
Topics: Animals; Blood Glucose; Body Composition; C-Peptide; Dietary Fats; Eating; Fatty Acids, Nonesterifie | 2002 |