Page last updated: 2024-10-19

palmitic acid and Glucose Intolerance

palmitic acid has been researched along with Glucose Intolerance in 16 studies

Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.

Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.

Research Excerpts

ExcerptRelevanceReference
" This study examined the effect of a novel neuroprotective curcuminoid, CNB-001 [4-((1E)-2-(5-(4-hydroxy-3-methoxystyryl-)-1-phenyl-1H-pyrazoyl-3-yl)vinyl)-2-methoxy-phenol], on glucose intolerance and insulin signaling in high-fat diet (HFD)-fed mice."7.80Novel curcumin derivative CNB-001 mitigates obesity-associated insulin resistance. ( Hua, Y; Lapchak, PA; Lehmann, TE; Nair, S; Panzhinskiy, E; Ren, J; Topchiy, E, 2014)
"C2C12 myotubes were challenged by palmitic acid (PA) to mimic the obese microenvironment and inflammation, cell vitality, and glucose utilization were determined."4.31Lunasin ameliorates glucose utilization in C2C12 myotubes and metabolites profile in diet-induced obese mice benefiting metabolic disorders. ( Chiang, CC; Hsieh, CC; Huang, CY; Huang, PY; Kuo, CH; Kuo, HC; Lin, PY, 2023)
" For primary skeletal muscle satellite cells, inhibition of differentiation was observed in palmitic acid-induced insulin resistance model."3.91Mitochondrial dysfunction and inhibition of myoblast differentiation in mice with high-fat-diet-induced pre-diabetes. ( Fan, S; Han, S; Hassan, HM; Jiang, Z; Sun, Z; Wang, L; Wang, T; Xu, D; Zhang, L; Zhao, G; Zhou, W, 2019)
" This study examined the effect of a novel neuroprotective curcuminoid, CNB-001 [4-((1E)-2-(5-(4-hydroxy-3-methoxystyryl-)-1-phenyl-1H-pyrazoyl-3-yl)vinyl)-2-methoxy-phenol], on glucose intolerance and insulin signaling in high-fat diet (HFD)-fed mice."3.80Novel curcumin derivative CNB-001 mitigates obesity-associated insulin resistance. ( Hua, Y; Lapchak, PA; Lehmann, TE; Nair, S; Panzhinskiy, E; Ren, J; Topchiy, E, 2014)
"Insulin sensitivity was assessed using a hyperinsulinemic-euglycemic clamp."2.82Altered Skeletal Muscle Fatty Acid Handling in Subjects with Impaired Glucose Tolerance as Compared to Impaired Fasting Glucose. ( Blaak, EE; Diamant, M; Goossens, GH; Jans, A; Jocken, JW; Konings, E; Moors, CC; van der Zijl, NJ, 2016)
"Non-alcoholic fatty liver disease (NAFLD), an emerging risk factor for diabetes, is now recognized as the most common liver disease worldwide."1.62Mesenchymal stem cell-conditioned medium improved mitochondrial function and alleviated inflammation and apoptosis in non-alcoholic fatty liver disease by regulating SIRT1. ( Chen, L; Cui, C; Cui, Y; Guo, X; He, Q; Hu, H; Liang, K; Sha, S; Song, J; Sun, L; Wang, C; Wang, L; Yang, M; Zang, N, 2021)
"The glucose intolerance was accompanied by a rise in the fasting plasma NEFA level."1.31Glucose intolerance induced by a high-fat/low-carbohydrate diet in rats effects of nonesterified fatty acids. ( Kaneko, T; Li, J; Matsui, H; Miura, Y; Qin, LQ; Sato, A; Wang, PY; Wang, Y, 2002)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (31.25)29.6817
2010's9 (56.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Huang, PY1
Chiang, CC1
Huang, CY1
Lin, PY1
Kuo, HC1
Kuo, CH1
Hsieh, CC1
Yang, M1
Cui, Y1
Song, J1
Cui, C1
Wang, L2
Liang, K1
Wang, C1
Sha, S1
He, Q1
Hu, H1
Guo, X1
Zang, N1
Sun, L1
Chen, L1
Luan, Y1
Zhang, F1
Cheng, Y1
Liu, J1
Huang, R1
Yan, M1
Wang, Y2
He, Z1
Lai, H1
Wang, H1
Ying, H1
Guo, F1
Zhai, Q1
Xu, D1
Jiang, Z1
Sun, Z1
Zhao, G1
Hassan, HM1
Fan, S1
Zhou, W1
Han, S1
Zhang, L1
Wang, T1
Panzhinskiy, E1
Hua, Y2
Lapchak, PA1
Topchiy, E1
Lehmann, TE1
Ren, J2
Nair, S2
Goossens, GH1
Moors, CC1
Jocken, JW1
van der Zijl, NJ1
Jans, A1
Konings, E1
Diamant, M1
Blaak, EE1
Talukder, MA1
Preda, M1
Ryzhova, L1
Prudovsky, I1
Pinz, IM1
Sutherland, LN1
Capozzi, LC1
Turchinsky, NJ1
Bell, RC1
Wright, DC1
Symons, JD1
McMillin, SL1
Riehle, C1
Tanner, J1
Palionyte, M1
Hillas, E1
Jones, D1
Cooksey, RC1
Birnbaum, MJ1
McClain, DA1
Zhang, QJ1
Gale, D1
Wilson, LJ1
Abel, ED1
Akerfeldt, MC1
Laybutt, DR1
Billestrup, N1
Carvalho-Filho, MA1
Carvalho, BM1
Oliveira, AG1
Guadagnini, D1
Ueno, M1
Dias, MM1
Tsukumo, DM1
Hirabara, SM1
Reis, LF1
Curi, R1
Carvalheira, JB1
Saad, MJ1
Zhang, Y1
Dolence, J1
Shi, GP1
Rocca, AS1
LaGreca, J1
Kalitsky, J1
Brubaker, PL1
Knuuti, J1
Takala, TO1
Någren, K1
Sipilä, H1
Turpeinen, AK1
Uusitupa, MI1
Nuutila, P1
Miura, Y1
Kaneko, T1
Li, J1
Qin, LQ1
Wang, PY1
Matsui, H1
Sato, A1

Trials

1 trial available for palmitic acid and Glucose Intolerance

ArticleYear
Altered Skeletal Muscle Fatty Acid Handling in Subjects with Impaired Glucose Tolerance as Compared to Impaired Fasting Glucose.
    Nutrients, 2016, Mar-14, Volume: 8, Issue:3

    Topics: Biomarkers; Blood Glucose; Diglycerides; Double-Blind Method; Fasting; Female; Gene Expression Regul

2016

Other Studies

15 other studies available for palmitic acid and Glucose Intolerance

ArticleYear
Lunasin ameliorates glucose utilization in C2C12 myotubes and metabolites profile in diet-induced obese mice benefiting metabolic disorders.
    Life sciences, 2023, Nov-15, Volume: 333

    Topics: Animals; Diet; Glucose; Glucose Intolerance; Inflammation; Insulin Resistance; Metabolic Diseases; M

2023
Mesenchymal stem cell-conditioned medium improved mitochondrial function and alleviated inflammation and apoptosis in non-alcoholic fatty liver disease by regulating SIRT1.
    Biochemical and biophysical research communications, 2021, 03-26, Volume: 546

    Topics: Animals; Apoptosis; Cell Line; Cells, Cultured; Culture Media, Conditioned; Diabetes Mellitus, Type

2021
Hemin Improves Insulin Sensitivity and Lipid Metabolism in Cultured Hepatocytes and Mice Fed a High-Fat Diet.
    Nutrients, 2017, Jul-26, Volume: 9, Issue:8

    Topics: Animals; Biomarkers; Blood Glucose; Cells, Cultured; Diet, High-Fat; Dose-Response Relationship, Dru

2017
Mitochondrial dysfunction and inhibition of myoblast differentiation in mice with high-fat-diet-induced pre-diabetes.
    Journal of cellular physiology, 2019, Volume: 234, Issue:5

    Topics: Adenosine Triphosphate; Animals; Blood Glucose; Cell Differentiation; Diabetes Mellitus, Type 2; Die

2019
Novel curcumin derivative CNB-001 mitigates obesity-associated insulin resistance.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 349, Issue:2

    Topics: Adiposity; Animals; Catalytic Domain; Cell Line; Cell Survival; Curcumin; Dietary Fats; Endoplasmic

2014
Heterozygous caveolin-3 mice show increased susceptibility to palmitate-induced insulin resistance.
    Physiological reports, 2016, Volume: 4, Issue:6

    Topics: Animals; Blood Glucose; Caveolae; Caveolin 3; CD36 Antigens; Cell Line; Diet, High-Fat; Disease Mode

2016
Time course of high-fat diet-induced reductions in adipose tissue mitochondrial proteins: potential mechanisms and the relationship to glucose intolerance.
    American journal of physiology. Endocrinology and metabolism, 2008, Volume: 295, Issue:5

    Topics: Adipose Tissue, White; AMP-Activated Protein Kinases; Animals; Blood Glucose; Body Weight; Dietary F

2008
Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.
    Circulation research, 2009, May-08, Volume: 104, Issue:9

    Topics: Animals; Blood Pressure; Cells, Cultured; Dietary Fats; Disease Models, Animal; Dose-Response Relati

2009
Inhibition of Id1 augments insulin secretion and protects against high-fat diet-induced glucose intolerance.
    Diabetes, 2011, Volume: 60, Issue:10

    Topics: Animals; Blood Glucose; Cell Line; Dietary Fats; Gene Expression Regulation; Glucose Intolerance; In

2011
ID'ing a novel inhibitor of β-cell function, Id1.
    Diabetes, 2011, Volume: 60, Issue:10

    Topics: Animals; Cell Differentiation; Diabetes Mellitus; Dietary Fats; DNA Fingerprinting; Enzymes; Gene Ex

2011
Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice.
    Endocrinology, 2012, Volume: 153, Issue:11

    Topics: Animals; Blood Glucose; Eating; eIF-2 Kinase; Glucose; Glucose Intolerance; Insulin Receptor Substra

2012
Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction.
    Diabetes, 2013, Volume: 62, Issue:2

    Topics: Animals; Apoptosis; Calcium; Cardiomegaly; Cathepsin K; Cell Line; Cytochromes c; Cytoplasm; Diet, H

2013
Monounsaturated fatty acid diets improve glycemic tolerance through increased secretion of glucagon-like peptide-1.
    Endocrinology, 2001, Volume: 142, Issue:3

    Topics: Administration, Oral; Animals; Body Weight; Cell Line; Dietary Fats; Duodenum; Eating; Fatty Acids;

2001
Myocardial fatty acid oxidation in patients with impaired glucose tolerance.
    Diabetologia, 2001, Volume: 44, Issue:2

    Topics: Blood Glucose; Carbon Radioisotopes; Cholesterol, HDL; Cholesterol, LDL; Coronary Circulation; Fasti

2001
Glucose intolerance induced by a high-fat/low-carbohydrate diet in rats effects of nonesterified fatty acids.
    Endocrine, 2002, Volume: 17, Issue:3

    Topics: Animals; Area Under Curve; Blood Glucose; Diet; Dietary Carbohydrates; Dietary Fats; Fatty Acids, No

2002