Page last updated: 2024-10-19

palmitic acid and Diabetic Retinopathy

palmitic acid has been researched along with Diabetic Retinopathy in 8 studies

Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.

Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

Research Excerpts

ExcerptRelevanceReference
" We then describe glial transcriptome alterations in response to systemic circulating factors that are upregulated in patients with diabetes and diabetes-related comorbidities; namely glucose in hyperglycemia, angiotensin II in hypertension, and the free fatty acid palmitic acid in hyperlipidemia."5.41Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis. ( Capozzi, ME; Padovani-Claudio, DA; Penn, JS; Ramos, CJ, 2023)
"Gambogic acid has been reported to have anti-inflammatory effect."1.62Gambogic acid ameliorates high glucose- and palmitic acid-induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo. ( Chen, J; Chen, L; Li, L; Zhang, J; Zhou, Y, 2021)
"The incidence of type 2 diabetes, the most common cause of diabetic retinopathy (DR), is rapidly on the rise in developed countries due to overconsumption of calorie rich diets."1.48Consumption of a high fat diet promotes protein O-GlcNAcylation in mouse retina via NR4A1-dependent GFAT2 expression. ( Dai, W; Dennis, MD; Dierschke, SK; Toro, AL, 2018)
"Although hyperglycemia is the main instigator in the development of diabetic retinopathy, dyslipidemia is also considered to play an important role."1.42Lipotoxicity augments glucotoxicity-induced mitochondrial damage in the development of diabetic retinopathy. ( Kowluru, A; Kowluru, RA; Kumar, B, 2015)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Alka, K1
Mohammad, G1
Kowluru, RA2
Padovani-Claudio, DA1
Ramos, CJ1
Capozzi, ME2
Penn, JS2
Chen, J1
Li, L1
Zhou, Y1
Zhang, J1
Chen, L1
Giblin, MJ1
Dai, W1
Dierschke, SK1
Toro, AL1
Dennis, MD1
Kumar, B1
Kowluru, A1
KEEN, H1
CHLOUVERAKIS, C1
Cacicedo, JM1
Benjachareowong, S1
Chou, E1
Ruderman, NB1
Ido, Y1

Reviews

1 review available for palmitic acid and Diabetic Retinopathy

ArticleYear
Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis.
    Progress in retinal and eye research, 2023, Volume: 94

    Topics: Angiotensin II; Diabetes Mellitus; Diabetic Retinopathy; Glucose; Humans; Hyperglycemia; Hypertensio

2023

Other Studies

7 other studies available for palmitic acid and Diabetic Retinopathy

ArticleYear
Regulation of serine palmitoyl-transferase and Rac1-Nox2 signaling in diabetic retinopathy.
    Scientific reports, 2022, 10-06, Volume: 12, Issue:1

    Topics: Animals; Ceramides; Cytosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic R

2022
Gambogic acid ameliorates high glucose- and palmitic acid-induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo.
    Cell stress & chaperones, 2021, Volume: 26, Issue:2

    Topics: Cell Line; Diabetic Retinopathy; Humans; Inflammation; NF-E2-Related Factor 2; Palmitic Acid; Xantho

2021
Palmitic Acid Induces Müller Cell Inflammation that is Potentiated by Co-treatment with Glucose.
    Scientific reports, 2018, 04-03, Volume: 8, Issue:1

    Topics: Diabetic Retinopathy; Drug Interactions; Ependymoglial Cells; Gene Expression Regulation; Glucose; H

2018
Consumption of a high fat diet promotes protein O-GlcNAcylation in mouse retina via NR4A1-dependent GFAT2 expression.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:12

    Topics: Acetylglucosamine; Acylation; Animals; Cell Line; Ceramides; Diabetes Mellitus, Type 2; Diabetic Ret

2018
Lipotoxicity augments glucotoxicity-induced mitochondrial damage in the development of diabetic retinopathy.
    Investigative ophthalmology & visual science, 2015, Volume: 56, Issue:5

    Topics: Animals; Cytochromes b; Diabetic Retinopathy; DNA Damage; DNA, Mitochondrial; Drug Synergism; Endoth

2015
METABOLISM OF ISOLATED RAT RETINA. THE ROLE OF NON-ESTERIFIED FATTY ACID.
    The Biochemical journal, 1965, Volume: 94

    Topics: Animals; Carbon Dioxide; Carbon Isotopes; Cattle; Diabetic Retinopathy; Esters; Fatty Acids; Fatty A

1965
Palmitate-induced apoptosis in cultured bovine retinal pericytes: roles of NAD(P)H oxidase, oxidant stress, and ceramide.
    Diabetes, 2005, Volume: 54, Issue:6

    Topics: Animals; Apoptosis; Cattle; Cells, Cultured; Ceramides; Diabetic Retinopathy; Gene Expression; NADPH

2005