Page last updated: 2024-10-19

palmitic acid and Diabetes Mellitus

palmitic acid has been researched along with Diabetes Mellitus in 53 studies

Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
" We then describe glial transcriptome alterations in response to systemic circulating factors that are upregulated in patients with diabetes and diabetes-related comorbidities; namely glucose in hyperglycemia, angiotensin II in hypertension, and the free fatty acid palmitic acid in hyperlipidemia."5.41Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis. ( Capozzi, ME; Padovani-Claudio, DA; Penn, JS; Ramos, CJ, 2023)
"Our data suggest three possible clinically actionable endotypes in primary OA: muscle weakness, arginine deficit and low inflammatory OA."4.02Endotypes of primary osteoarthritis identified by plasma metabolomics analysis. ( Furey, A; Liu, M; Rahman, P; Randell, EW; Sun, G; Werdyani, S; Zhai, G; Zhang, H, 2021)
"Palmitic acid effects were dependent on TLR4 and impaired by methyltransferase inhibition and AMPK activation."1.72Weight cycling induces innate immune memory in adipose tissue macrophages. ( Boney, LY; Caslin, HL; Cottam, MA; Hasty, AH; Piñon, JM, 2022)
"The onset of NIDDM in obese Zucker diabetic fatty (fa/fa) rats is preceded by a striking increase in the plasma levels of free fatty acids (FFAs) and by a sixfold rise in triglyceride content in the pancreatic islets."1.30Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM. ( Esser, V; Hirose, H; Lee, Y; McGarry, JD; Unger, RH; Zhou, YT, 1997)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199014 (26.42)18.7374
1990's4 (7.55)18.2507
2000's5 (9.43)29.6817
2010's18 (33.96)24.3611
2020's12 (22.64)2.80

Authors

AuthorsStudies
Liu, S1
Da, J1
Yu, J1
Dong, R1
Yuan, J1
Yu, F1
Zha, Y1
Pérez-Martí, A1
Ramakrishnan, S1
Li, J1
Dugourd, A1
Molenaar, MR1
De La Motte, LR1
Grand, K1
Mansouri, A1
Parisot, M1
Lienkamp, SS1
Saez-Rodriguez, J1
Simons, M1
Xu, SX1
Han, YW1
Guo, JL1
Bian, XK1
Hu, HM1
Lee, SC1
Başçıl Tütüncü, N1
Verdi, H1
Yalçın, Y1
Baysan Çebi, P1
Kınık, S1
Tütüncü, T1
Ataç, FB1
Zhao, C1
Li, L1
Li, C1
Tang, C1
Cai, J1
Liu, Y3
Yang, J2
Xi, Y1
Yang, M1
Jiang, N1
Han, Y2
Luo, S1
Xiao, L1
Sun, L1
Zhang, W1
Hu, Z2
Wu, S1
Zhu, J1
Wu, G1
Ying, P1
Bao, Z1
Ding, Z1
Tan, X1
Caslin, HL1
Cottam, MA1
Piñon, JM1
Boney, LY1
Hasty, AH1
Padovani-Claudio, DA1
Ramos, CJ1
Capozzi, ME1
Penn, JS1
Wang, X2
Zhang, JQ1
Xiu, CK1
Fang, JY1
Lei, Y1
Werdyani, S1
Liu, M2
Zhang, H1
Sun, G1
Furey, A1
Randell, EW1
Rahman, P1
Zhai, G1
Choi, HE1
Kim, Y1
Lee, HJ1
Cheon, HG1
Hilvo, M1
Salonurmi, T1
Havulinna, AS1
Kauhanen, D1
Pedersen, ER1
Tell, GS1
Meyer, K1
Teeriniemi, AM1
Laatikainen, T1
Jousilahti, P1
Savolainen, MJ1
Nygård, O1
Salomaa, V1
Laaksonen, R1
Dohl, J1
Foldi, J1
Heller, J1
Gasier, HG1
Deuster, PA1
Yu, T1
Bian, Y1
Ma, X1
Wang, R1
Yuan, H1
Chen, N1
Du, Y1
Jiang, X1
Deng, B1
Xiao, J1
Jin, J1
Huang, Z1
Kebede, MA1
Oler, AT1
Gregg, T1
Balloon, AJ1
Johnson, A1
Mitok, K1
Rabaglia, M1
Schueler, K1
Stapleton, D1
Thorstenson, C1
Wrighton, L1
Floyd, BJ1
Richards, O1
Raines, S1
Eliceiri, K1
Seidah, NG1
Rhodes, C1
Keller, MP1
Coon, JL1
Audhya, A1
Attie, AD1
Gjoni, E1
Brioschi, L1
Cinque, A1
Coant, N1
Islam, MN1
Ng, CK1
Verderio, C1
Magnan, C1
Riboni, L1
Viani, P1
Le Stunff, H1
Giussani, P1
Lemaitre, RN1
Fretts, AM1
Sitlani, CM1
Biggs, ML1
Mukamal, K1
King, IB1
Song, X1
Djoussé, L1
Siscovick, DS1
McKnight, B1
Sotoodehnia, N1
Kizer, JR1
Mozaffarian, D1
Tian, X1
Li, Y1
Liu, D1
Zhang, X1
Zhang, Q1
Yan, C1
Zhao, L1
Ni, Y1
Yu, H1
Zhang, P1
Zhao, A1
Bao, Y1
Liu, J1
Chen, T1
Xie, G1
Panee, J1
Chen, W1
Rajani, C1
Wei, R1
Su, M1
Jia, W2
Kishino, T1
Watanabe, K1
Urata, T1
Takano, M1
Uemura, T1
Nishikawa, K1
Mine, Y1
Matsumoto, M1
Ohtsuka, K1
Ohnishi, H1
Mori, H1
Takahashi, S1
Ishida, H1
Watanabe, T1
Chae, SY1
Choi, YG1
Son, S1
Jung, SY1
Lee, DS1
Lee, KC3
Xu, M1
Wang, W1
Frontera, JR1
Neely, MC1
Lu, J1
Aires, D1
Hsu, FF1
Turk, J1
Swerdlow, RH1
Carlson, SE1
Zhu, H1
Billestrup, N1
Lee, J2
Lee, C2
Kim, I1
Moon, HR1
Kim, TH2
Oh, KT1
Lee, ES2
Youn, YS2
Turban, S1
Liu, X1
Ramage, L1
Webster, SP1
Walker, BR1
Dunbar, DR1
Mullins, JJ1
Seckl, JR1
Morton, NM1
Magkos, F1
Fabbrini, E1
Conte, C1
Patterson, BW1
Klein, S1
Ou, HY1
Wu, HT1
Hung, HC1
Yang, YC1
Wu, JS1
Chang, CJ1
Shin, BS1
Chi, SC1
Park, ES1
Qi, Y1
Xia, P1
FORD, CR1
STEVENS, R1
BOLINGER, RE1
MORRIS, JH1
ISSEKUTZ, B1
MILLER, HI1
RODAHL, K1
DOI, H2
OKAMOTO, H2
KATSURA, E1
AMAKO, T1
TARRANT, ME1
MAHLER, R1
ASHMORE, J1
SCHWARTZ, S1
BRODY, JI1
BEIZER, LH1
OGINO, K1
Allagnat, F1
Alonso, F1
Martin, D1
Abderrahmani, A1
Waeber, G1
Haefliger, JA1
Pieper, GM1
Salhany, JM1
Murray, WJ1
Wu, ST1
Eliot, RS1
Yue, KT1
Davis, JW1
Phillips, PE1
Graham, BA1
Laitinen, J1
Uusitupa, M1
Ahola, I1
Siitonen, O1
Lee, Y2
Hirose, H1
Zhou, YT2
Esser, V1
McGarry, JD1
Unger, RH3
Shimabukuro, M2
Levi, M1
Wang, MY1
Trinh, KY1
Chen, JL1
Newgard, CB1
Ide, T1
Nakazawa, T1
Mochizuki, T1
Murakami, K1
Belke, DD1
Larsen, TS1
Gibbs, EM1
Severson, DL1
Bassilian, S1
Ahmed, S1
Lim, SK1
Boros, LG1
Mao, CS1
Lee, WN1
Murtiashaw, MH1
Winterhalter, KH1
Yamaguchi, M1
Matsunaga, R1
Hara, S1
Nakamura, M1
Ohkura, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Cardiovascular Health Study[NCT00005133]5,888 participants (Actual)Observational1988-06-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for palmitic acid and Diabetes Mellitus

ArticleYear
Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis.
    Progress in retinal and eye research, 2023, Volume: 94

    Topics: Angiotensin II; Diabetes Mellitus; Diabetic Retinopathy; Glucose; Humans; Hyperglycemia; Hypertensio

2023

Trials

3 trials available for palmitic acid and Diabetes Mellitus

ArticleYear
[
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2022, Sep-20, Volume: 42, Issue:9

    Topics: Animals; Anthracenes; Apoptosis; Autophagy; Blood Glucose; Diabetes Mellitus; Drinking Water; Drugs,

2022
Relationship between adipose tissue lipolytic activity and skeletal muscle insulin resistance in nondiabetic women.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:7

    Topics: Adipose Tissue; Adult; Aged; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucose Clamp Te

2012
Metabolic and dietary determinants of serum lipids in obese patients with recently diagnosed non-insulin-dependent diabetes.
    Annals of medicine, 1994, Volume: 26, Issue:2

    Topics: Adult; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet, Reducing; Female; Follow-Up

1994

Other Studies

49 other studies available for palmitic acid and Diabetes Mellitus

ArticleYear
Renal tubule ectopic lipid deposition in diabetic kidney disease rat model and in vitro mechanism of leptin intervention.
    Journal of physiology and biochemistry, 2022, Volume: 78, Issue:2

    Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus; Diabetic Nephropathies; Leptin; Lipid Met

2022
Reducing lipid bilayer stress by monounsaturated fatty acids protects renal proximal tubules in diabetes.
    eLife, 2022, 05-12, Volume: 11

    Topics: Animals; Diabetes Mellitus; Endoplasmic Reticulum Stress; Fatty Acids; Fatty Acids, Monounsaturated;

2022
The binding between NPM and H2B proteins signals for the diabetes-associated centrosome amplification.
    Cell biochemistry and function, 2022, Volume: 40, Issue:5

    Topics: Centrosome; Diabetes Mellitus; Glucose; HCT116 Cells; Histones; Humans; Insulin; Molecular Docking S

2022
Beta-Cell Golgi Stress Response to Lipotoxicity and Glucolipotoxicity: A Preliminary Study of a Potential Mechanism of Beta-Cell Failure in Posttransplant Diabetes and Intraportal Islet Transplant.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2022, Volume: 20, Issue:6

    Topics: Animals; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus; Glucose; Golgi Apparatus; P

2022
PACS-2 deficiency in tubular cells aggravates lipid-related kidney injury in diabetic kidney disease.
    Molecular medicine (Cambridge, Mass.), 2022, 09-23, Volume: 28, Issue:1

    Topics: Animals; Cholesterol; Diabetes Mellitus; Diabetic Nephropathies; Glucose; Hypercholesterolemia; Kidn

2022
6-Gingerol Alleviates Ferroptosis and Inflammation of Diabetic Cardiomyopathy via the Nrf2/HO-1 Pathway.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Animals; Diabetes Mellitus; Diabetic Cardiomyopathies; Glucose; Inflammation; Mice; NF-E2-Related Fa

2022
Weight cycling induces innate immune memory in adipose tissue macrophages.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adipose Tissue; Animals; Culture Media, Conditioned; Diabetes Mellitus; Glucose; Insulin Resistance;

2022
Ginseng-Sanqi-Chuanxiong (GSC) Extracts Ameliorate Diabetes-Induced Endothelial Cell Senescence through Regulating Mitophagy via the AMPK Pathway.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: AMP-Activated Protein Kinases; Autophagy; Cell Survival; Cellular Senescence; Diabetes Mellitus; Dru

2020
Endotypes of primary osteoarthritis identified by plasma metabolomics analysis.
    Rheumatology (Oxford, England), 2021, 06-18, Volume: 60, Issue:6

    Topics: Aged; Arginine; Body Mass Index; Carnitine; Case-Control Studies; Coronary Disease; Diabetes Mellitu

2021
Novel FoxO1 inhibitor, JY-2, ameliorates palmitic acid-induced lipotoxicity and gluconeogenesis in a murine model.
    European journal of pharmacology, 2021, May-15, Volume: 899

    Topics: Animals; Blood Glucose; Diabetes Mellitus; Diet, High-Fat; Disease Models, Animal; Gene Expression R

2021
Ceramide stearic to palmitic acid ratio predicts incident diabetes.
    Diabetologia, 2018, Volume: 61, Issue:6

    Topics: Aged; Angina Pectoris; Body Mass Index; Ceramides; Cohort Studies; Coronary Angiography; Diabetes Me

2018
Acclimation of C
    Life sciences, 2018, Oct-15, Volume: 211

    Topics: Acclimatization; Animals; Cells, Cultured; Diabetes Mellitus; Glucose; Mice; Mitochondria; Myoblasts

2018
Human amnion-derived mesenchymal stem cells promote osteogenesis of human bone marrow mesenchymal stem cells against glucolipotoxicity.
    FEBS open bio, 2019, Volume: 9, Issue:1

    Topics: Amnion; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coculture Tech

2019
Lipopolysaccharide and palmitic acid synergistically induced MCP-1 production via MAPK-meditated TLR4 signaling pathway in RAW264.7 cells.
    Lipids in health and disease, 2019, Mar-25, Volume: 18, Issue:1

    Topics: Animals; Chemokine CCL2; Diabetes Mellitus; Disease Models, Animal; Drug Synergism; Gene Expression

2019
SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:10

    Topics: Animals; Diabetes Mellitus; Gene Deletion; Genotype; Glucose; Insulin; Insulin-Secreting Cells; Mice

2014
Glucolipotoxicity impairs ceramide flow from the endoplasmic reticulum to the Golgi apparatus in INS-1 β-cells.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Animals; Cell Line; Cell Survival; Ceramides; Diabetes Mellitus; Endoplasmic Reticulum; Endoplasmic

2014
Plasma phospholipid very-long-chain saturated fatty acids and incident diabetes in older adults: the Cardiovascular Health Study.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:5

    Topics: Aged; Aged, 80 and over; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus; Diet; Eicosanoic Ac

2015
Up-Regulation of CREG Expression by the Transcription Factor GATA1 Inhibits High Glucose- and High Palmitate-Induced Apoptosis in Human Umbilical Vein Endothelial Cells.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Apoptosis; Atherosclerosis; Base Sequence; Diabetes Mellitus; Dose-Response Relationship, Drug; GATA

2016
Serum stearic acid/palmitic acid ratio as a potential predictor of diabetes remission after Roux-en-Y gastric bypass in obesity.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017, Volume: 31, Issue:4

    Topics: Acetyltransferases; Adult; Aged; Biomarkers; Diabetes Mellitus; Fatty Acid Elongases; Female; Gastri

2017
Visceral fat thickness in overweight men correlates with alterations in serum fatty acid composition.
    Clinica chimica acta; international journal of clinical chemistry, 2008, Volume: 398, Issue:1-2

    Topics: Adiposity; Adult; Aged; Alcohol Drinking; Body Mass Index; Chromatography, Gas; Diabetes Mellitus; F

2008
The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, May-21, Volume: 144, Issue:1

    Topics: Animals; Antigens; Diabetes Mellitus; Diabetes Mellitus, Type 2; Exenatide; Fatty Acids; Glucagon-Li

2010
Ncb5or deficiency increases fatty acid catabolism and oxidative stress.
    The Journal of biological chemistry, 2011, Apr-01, Volume: 286, Issue:13

    Topics: Animals; Cytochrome-B(5) Reductase; Diabetes Mellitus; Diabetes Mellitus, Lipoatrophic; Gene Express

2011
ID'ing a novel inhibitor of β-cell function, Id1.
    Diabetes, 2011, Volume: 60, Issue:10

    Topics: Animals; Cell Differentiation; Diabetes Mellitus; Dietary Fats; DNA Fingerprinting; Enzymes; Gene Ex

2011
Preparation and evaluation of palmitic acid-conjugated exendin-4 with delayed absorption and prolonged circulation for longer hypoglycemia.
    International journal of pharmaceutics, 2012, Mar-15, Volume: 424, Issue:1-2

    Topics: Absorption; Animals; Blood Glucose; Delayed-Action Preparations; Diabetes Mellitus; Diabetes Mellitu

2012
Optimal elevation of β-cell 11β-hydroxysteroid dehydrogenase type 1 is a compensatory mechanism that prevents high-fat diet-induced β-cell failure.
    Diabetes, 2012, Volume: 61, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Cyclic AMP-Dependent Protein Kinases; Cyclin-D

2012
Endoplasmic reticulum stress induces the expression of fetuin-A to develop insulin resistance.
    Endocrinology, 2012, Volume: 153, Issue:7

    Topics: Aged; alpha-2-HS-Glycoprotein; Animals; Biomarkers; Diabetes Mellitus; Endoplasmic Reticulum; Fatty

2012
Self-assembled glycol chitosan nanogels containing palmityl-acylated exendin-4 peptide as a long-acting anti-diabetic inhalation system.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Aug-10, Volume: 161, Issue:3

    Topics: Acylation; Administration, Inhalation; Animals; Chitosan; Desoxycorticosterone; Diabetes Mellitus; D

2012
Cellular inhibitor of apoptosis protein-1 (cIAP1) plays a critical role in β-cell survival under endoplasmic reticulum stress: promoting ubiquitination and degradation of C/EBP homologous protein (CHOP).
    The Journal of biological chemistry, 2012, Sep-14, Volume: 287, Issue:38

    Topics: Animals; Cell Survival; Diabetes Mellitus; Endoplasmic Reticulum; HEK293 Cells; Humans; Inhibitor of

2012
Turnover of palmitate C-14 in diabetics and normals.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 113

    Topics: Diabetes Mellitus; Humans; Palmitates; Palmitic Acid

1963
EFFECT OF EXERCISE ON FFA METABOLISM OF PANCREATECTOMIZED DOGS.
    The American journal of physiology, 1963, Volume: 205

    Topics: Animals; Blood Chemical Analysis; Blood Glucose; Carbon Isotopes; Diabetes Mellitus; Dogs; Fatty Aci

1963
[CLINICAL STUDIES ON EFFECT OF GLUCOSE ON LIPIDS, ESPECIALLY, NEFA METABOLISM].
    Naika hokan. Japanese archives of internal medicine, 1963, Volume: 10

    Topics: Aging; Arteriosclerosis; Blood Chemical Analysis; Blood Glucose; Blood Proteins; Carbohydrate Metabo

1963
[EFFECT OF INSULIN ON GLUCOSE AND LIPIDS ESPECIALLY NEFA METABOLISM].
    Naika hokan. Japanese archives of internal medicine, 1963, Volume: 10

    Topics: Aging; Blood Chemical Analysis; Blood Proteins; Carbohydrate Metabolism; Carbon Isotopes; Cholestero

1963
[DIET IN DISORDERS OF LIPID METABOLISM].
    Wiener medizinische Wochenschrift (1946), 1963, Dec-14, Volume: 113

    Topics: Diabetes Mellitus; Diet; Diet Therapy; Fats, Unsaturated; Fatty Acids; Fatty Acids, Essential; Human

1963
[NUTRITIONAL ASPECTS IN CLINICAL MEDICINE. IV. LIPIDS AND VITAMINS. EFFECTS OF VITAMINS ON LIPID METABOLISM IN DIABETES MELLITUS].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1963, Oct-10, Volume: 52

    Topics: Acetates; Diabetes Mellitus; Fatty Acids; Fatty Acids, Essential; Lipid Metabolism; Palmitic Acid; P

1963
[STUDIES ON LIPID METABOLISM IN LIVER INJURY].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1964, Apr-10, Volume: 53

    Topics: Blood Protein Electrophoresis; Diabetes Mellitus; Lipid Metabolism; Liver Diseases; Palmitic Acid; R

1964
STUDIES IN EXPERIMENTAL DIABETES. IV. FREE FATTY ACID MOBILIZATION.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adipose Tissue; Animals; Blood Glucose; Carbon Isotopes; Diabetes Mellitus; Diabetes Mellitus, Exper

1964
LIPID THROMBOPLASTINS AND MYOCARDIAL INFARCTION.
    The American journal of the medical sciences, 1965, Volume: 249

    Topics: Angina Pectoris; Blood Coagulation; Blood Coagulation Tests; Cholesterol; Diabetes Mellitus; Dietary

1965
CLINICAL STUDY ON LIPID METABOLISM. EFFECT OF GLUCOSE AND INSULIN ON NEFA METABOLISM.
    Japanese circulation journal, 1965, Volume: 29

    Topics: Arteriosclerosis; Carbohydrate Metabolism; Carbon Isotopes; Diabetes Mellitus; Fatty Acids; Fatty Ac

1965
ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells.
    The Journal of biological chemistry, 2008, Feb-29, Volume: 283, Issue:9

    Topics: Animals; Cell Line, Tumor; Connexins; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP-

2008
Abnormal phosphocreatine metabolism in perfused diabetic hearts. A 31P nuclear-magnetic-resonance study.
    The Biochemical journal, 1983, Feb-15, Volume: 210, Issue:2

    Topics: Adenosine Triphosphate; Animals; Diabetes Mellitus; In Vitro Techniques; Magnetic Resonance Spectros

1983
Effect of glucose on plasma concentrations of individual non-esterified fatty acids of non-diabetic and insulin-independent diabetic men.
    Postgraduate medical journal, 1981, Volume: 57, Issue:672

    Topics: Adult; Aged; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose; Glucose Tolerance Test; Humans;

1981
Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM.
    Diabetes, 1997, Volume: 46, Issue:3

    Topics: Acyl-CoA Oxidase; Animals; Brain; Cells, Cultured; Coenzyme A Ligases; Diabetes Mellitus; Diabetes M

1997
Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-03, Volume: 95, Issue:5

    Topics: Animals; Apoptosis; Cells, Cultured; Ceramides; Chromans; Coenzyme A Ligases; Diabetes Mellitus; Dia

1998
Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function.
    Diabetes, 1999, Volume: 48, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenoviridae; Animals; Diabetes Mellitus; Gene Expres

1999
Tissue-specific actions of antidiabetic thiazolidinediones on the reduced fatty acid oxidation in skeletal muscle and liver of Zucker diabetic fatty rats.
    Metabolism: clinical and experimental, 2000, Volume: 49, Issue:4

    Topics: Administration, Oral; Animals; Chromans; Diabetes Mellitus; Fatty Acids; Hypoglycemic Agents; Liver;

2000
Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:5

    Topics: Animals; Blood Glucose; Blood Pressure; Carbon Radioisotopes; Cardiac Output; Diabetes Mellitus; Fat

2000
Loss of regulation of lipogenesis in the Zucker diabetic rat. II. Changes in stearate and oleate synthesis.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:3

    Topics: Adipose Tissue; Animals; Deuterium; Diabetes Mellitus; Dietary Carbohydrates; Dietary Fats; Epididym

2002
Non-enzymatic glycation of human albumin does not alter its palmitate binding.
    Diabetologia, 1986, Volume: 29, Issue:6

    Topics: Biological Transport, Active; Cell Line; Diabetes Mellitus; Erythrocytes; Fatty Acids; Humans; In Vi

1986
Highly sensitive determination of free fatty acids in human serum by high-performance liquid chromatography with fluorescence detection.
    Journal of chromatography, 1986, Feb-14, Volume: 375, Issue:1

    Topics: Adult; Chromatography, High Pressure Liquid; Diabetes Mellitus; Fatty Acids, Nonesterified; Female;

1986