Page last updated: 2024-10-19

palmitic acid and Cirrhosis

palmitic acid has been researched along with Cirrhosis in 10 studies

Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.

Research Excerpts

ExcerptRelevanceReference
"In primary hepatocytes and AML-12 cells, JM-2 treatment significantly suppressed palmitic acid (PA)-induced JNK activation and PA-induced inflammation and cell apoptosis."4.31A small-molecule JNK inhibitor JM-2 attenuates high-fat diet-induced non-alcoholic fatty liver disease in mice. ( Jin, L; Liang, G; Lou, S; Luo, W; Wang, M; Yang, B; Ye, L; Zhang, Q; Zhang, Y; Zhu, W, 2023)
" To simulate a similar in-vivo condition, we persuaded insulin resistance in H9c2 cells by palmitic acid (PA) treatment."4.12Empagliflozin prohibits high-fructose diet-induced cardiac dysfunction in rats via attenuation of mitochondria-driven oxidative stress. ( Alam, MJ; Arava, S; Banerjee, SK; Bugga, P; Katare, P; Maulik, SK; Meghwani, H; Mohammed, SA, 2022)
" Here, we report that KIM-1 mediates PT uptake of palmitic acid (PA)-bound albumin, leading to enhanced tubule injury with DNA damage, PT cell-cycle arrest, interstitial inflammation and fibrosis, and secondary glomerulosclerosis."4.02KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease. ( Ajay, AK; Bonventre, JV; Brooks, CR; Chang, JH; Galichon, P; Hawkins, J; Henderson, JM; Ichimura, T; Kishi, S; Kuchroo, VK; Li, J; Li, L; Mori, Y; Mou, S; Palmer, SC; Sabbisetti, VS; Woo, HM; Xiao, S; Zhao, H, 2021)
" We observed that palmitic acid treatment in cardiac-derived H9c2 cells induced a significant increase in reactive oxygen species, inflammation, apoptosis, fibrosis and hypertrophy."3.83Inhibition of inflammation and oxidative stress by an imidazopyridine derivative X22 prevents heart injury from obesity. ( Chen, G; Chen, X; Li, X; Liang, G; Lu, K; Peng, K; Qian, Y; Xu, Z; Zhang, Y; Zhong, P, 2016)
"Renal fibrosis is a potent predictor of progression in patients and is often accompanied by inflammation and oxidative stress; however, the mechanisms involved in these alterations are not well established."1.62Role of endoplasmic reticulum stress in renal damage after myocardial infarction. ( Cachofeiro, V; de la Fuente-Chávez, L; Delgado-Valero, B; Islas, F; Luaces, M; Martínez-Martínez, E; Ramchandani, B; Romero-Miranda, A; Visitación Bartolomé, M, 2021)
"Treatment with Senicapoc decreased palmitic acid-driven HepG2 cell death."1.46Anti-steatotic and anti-fibrotic effects of the KCa3.1 channel inhibitor, Senicapoc, in non-alcoholic liver disease. ( Duan, B; Goldberg, ID; Hao, YJ; Jiang, K; Jung, D; Li, JS; McCormack, S; Narayan, P; Paka, L; Shi, J; Smith, DE; Yamin, M; Zhou, P, 2017)
"As obesity is one of the major risk factors of chronic and end-stage renal disease, we studied the role of Smad3 signaling in the pathogenesis of obesity-related renal disease."1.42Smad3 deficiency protects mice from obesity-induced podocyte injury that precedes insulin resistance. ( Bertram, JF; Caruana, G; Dai, L; Fu, P; Howard, V; Jiang, X; Li, J; Nikolic-Paterson, DJ; Puelles, VG; Qu, X; Ren, Y; Sleeman, MW; Sun, YB, 2015)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (50.00)24.3611
2020's5 (50.00)2.80

Authors

AuthorsStudies
Bugga, P1
Mohammed, SA1
Alam, MJ1
Katare, P1
Meghwani, H1
Maulik, SK1
Arava, S1
Banerjee, SK1
Jin, L1
Wang, M1
Yang, B1
Ye, L1
Zhu, W1
Zhang, Q1
Lou, S1
Zhang, Y2
Luo, W1
Liang, G2
Gao, LP1
Chen, HC1
Ma, ZL1
Chen, AD1
Du, HL1
Yin, J1
Jing, YH1
Delgado-Valero, B1
de la Fuente-Chávez, L1
Romero-Miranda, A1
Visitación Bartolomé, M1
Ramchandani, B1
Islas, F1
Luaces, M1
Cachofeiro, V1
Martínez-Martínez, E1
Mori, Y1
Ajay, AK1
Chang, JH1
Mou, S1
Zhao, H1
Kishi, S1
Li, J2
Brooks, CR1
Xiao, S1
Woo, HM1
Sabbisetti, VS1
Palmer, SC1
Galichon, P1
Li, L1
Henderson, JM1
Kuchroo, VK1
Hawkins, J1
Ichimura, T1
Bonventre, JV1
Paka, L1
Smith, DE1
Jung, D1
McCormack, S1
Zhou, P1
Duan, B1
Li, JS1
Shi, J1
Hao, YJ1
Jiang, K1
Yamin, M1
Goldberg, ID1
Narayan, P1
Khan, S1
Cabral, PD1
Schilling, WP1
Schmidt, ZW1
Uddin, AN1
Gingras, A1
Madhavan, SM1
Garvin, JL1
Schelling, JR1
Sun, YB1
Qu, X1
Howard, V1
Dai, L1
Jiang, X1
Ren, Y1
Fu, P1
Puelles, VG1
Nikolic-Paterson, DJ1
Caruana, G1
Bertram, JF1
Sleeman, MW1
Qian, Y1
Zhong, P1
Peng, K1
Xu, Z1
Chen, X1
Lu, K1
Chen, G1
Li, X1
Lee, L1
Ito, T1
Nakamura, T1
Jensen, RT1
Igarashi, H1
Takayanagi, R1

Other Studies

10 other studies available for palmitic acid and Cirrhosis

ArticleYear
Empagliflozin prohibits high-fructose diet-induced cardiac dysfunction in rats via attenuation of mitochondria-driven oxidative stress.
    Life sciences, 2022, Oct-15, Volume: 307

    Topics: Animals; Benzhydryl Compounds; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mel

2022
A small-molecule JNK inhibitor JM-2 attenuates high-fat diet-induced non-alcoholic fatty liver disease in mice.
    International immunopharmacology, 2023, Volume: 115

    Topics: Animals; Diet, High-Fat; Fibrosis; Hepatocytes; Inflammation; Liver; Mice; Mice, Inbred C57BL; Non-a

2023
Fibrillation of human islet amyloid polypeptide and its toxicity to pancreatic β-cells under lipid environment.
    Biochimica et biophysica acta. General subjects, 2020, Volume: 1864, Issue:1

    Topics: Amyloid; Apoptosis; Cell Membrane; Endoplasmic Reticulum Stress; Fatty Acids, Nonesterified; Fibrosi

2020
Role of endoplasmic reticulum stress in renal damage after myocardial infarction.
    Clinical science (London, England : 1979), 2021, 01-15, Volume: 135, Issue:1

    Topics: Adult; Animals; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum Stress; Female; Fibro

2021
KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease.
    Cell metabolism, 2021, 05-04, Volume: 33, Issue:5

    Topics: Animals; Benzamides; Cell Cycle Checkpoints; Diabetes Mellitus, Experimental; Diabetic Nephropathies

2021
Anti-steatotic and anti-fibrotic effects of the KCa3.1 channel inhibitor, Senicapoc, in non-alcoholic liver disease.
    World journal of gastroenterology, 2017, Jun-21, Volume: 23, Issue:23

    Topics: Acetamides; Animals; Apoptosis; Biomarkers, Tumor; Diet, High-Fat; Fibrosis; Gene Expression Regulat

2017
Kidney Proximal Tubule Lipoapoptosis Is Regulated by Fatty Acid Transporter-2 (FATP2).
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:1

    Topics: Animals; Apoptosis; Atrophy; Biological Transport; Cells, Cultured; Coenzyme A Ligases; Epithelial C

2018
Smad3 deficiency protects mice from obesity-induced podocyte injury that precedes insulin resistance.
    Kidney international, 2015, Volume: 88, Issue:2

    Topics: Animals; Cells, Cultured; Dietary Fats; Enzyme Inhibitors; Fibrosis; Flavonoids; Gene Knockdown Tech

2015
Inhibition of inflammation and oxidative stress by an imidazopyridine derivative X22 prevents heart injury from obesity.
    Journal of cellular and molecular medicine, 2016, Volume: 20, Issue:8

    Topics: Animals; Apoptosis; Blood Glucose; Cardiomegaly; Cell Line; Diet, High-Fat; Fibrosis; Heart Injuries

2016
Antifibrotic Effect of Saturated Fatty Acids via Endoplasmic Reticulum Stress Response in Rat Pancreatic Stellate Cells.
    Pancreas, 2017, Volume: 46, Issue:3

    Topics: Actins; Animals; Apoptosis; Cells, Cultured; Diet, High-Fat; Endoplasmic Reticulum Stress; Enzyme In

2017