palmitic acid has been researched along with Cirrhosis, Liver in 17 studies
Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six control subjects and 10 patients with (n = 5) and without (n = 5) cirrhotic ascites were fed [1-(13)C]palmitic and oleic acids in a test meal." | 3.73 | Absorption and transport of dietary long-chain fatty acids in cirrhosis: a stable-isotope-tracing study. ( Cabré, E; Corominas, A; Fluvià, L; Gassull, MA; Hernández-Pérez, JM; Pastor, C, 2005) |
| "Auranofin reduced liver fibrosis and lipid accumulation in NASH model mice fed on a Western diet." | 1.72 | Auranofin attenuates hepatic steatosis and fibrosis in nonalcoholic fatty liver disease via NRF2 and NF- κB signaling pathways. ( Jun, DW; Kang, HT; Kim, HS; Koh, DH; Lee, SM; Oh, JH; Roh, YJ, 2022) |
| "Dietary palmitic acid (PA) promotes liver fibrosis in patients with nonalcoholic steatohepatitis (NASH)." | 1.62 | The mechanism of increased intestinal palmitic acid absorption and its impact on hepatic stellate cell activation in nonalcoholic steatohepatitis. ( Hanayama, M; Hiasa, Y; Ikeda, Y; Liu, S; Matsuura, B; Mogi, M; Takeshita, E; Utsunomiya, H; Yamamoto, Y; Yoshida, O, 2021) |
| "Treatment with Senicapoc decreased palmitic acid-driven HepG2 cell death." | 1.46 | Anti-steatotic and anti-fibrotic effects of the KCa3.1 channel inhibitor, Senicapoc, in non-alcoholic liver disease. ( Duan, B; Goldberg, ID; Hao, YJ; Jiang, K; Jung, D; Li, JS; McCormack, S; Narayan, P; Paka, L; Shi, J; Smith, DE; Yamin, M; Zhou, P, 2017) |
| "Liver fibrosis is characterized by an activation of hepatic stellate cells (HSC)." | 1.33 | Growth arrest and decrease of alpha-SMA and type I collagen expression by palmitic acid in the rat hepatic stellate cell line PAV-1. ( Abergel, A; Chassard, C; Darcha, C; Dechelotte, P; Dif, N; Gaillard-Martinie, B; Marcand-Sauvant, J; Rock, E; Sapin, V; Sauvant, P, 2006) |
| "Palmitic acid was the most representative saturated FFA (which together accounted for 2." | 1.29 | Free fatty acid analysis in ascitic fluid improves diagnosis in malignant abdominal tumors. ( Gasbarrini, G; Greco, AV; Mingrone, G, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SM | 1 |
| Koh, DH | 1 |
| Jun, DW | 1 |
| Roh, YJ | 1 |
| Kang, HT | 1 |
| Oh, JH | 1 |
| Kim, HS | 1 |
| Aggarwal, S | 1 |
| Yadav, V | 1 |
| Maiwall, R | 1 |
| Rastogi, A | 1 |
| Pamecha, V | 1 |
| Bedi, O | 1 |
| Maras, JS | 1 |
| Trehanpati, N | 1 |
| Ramakrishna, G | 1 |
| Schilcher, K | 1 |
| Dayoub, R | 1 |
| Kubitza, M | 1 |
| Riepl, J | 1 |
| Klein, K | 1 |
| Buechler, C | 1 |
| Melter, M | 1 |
| Weiss, TS | 1 |
| Hanayama, M | 1 |
| Yamamoto, Y | 2 |
| Utsunomiya, H | 1 |
| Yoshida, O | 1 |
| Liu, S | 1 |
| Mogi, M | 1 |
| Matsuura, B | 2 |
| Takeshita, E | 1 |
| Ikeda, Y | 2 |
| Hiasa, Y | 2 |
| Lee, YS | 1 |
| Kim, SY | 1 |
| Ko, E | 1 |
| Lee, JH | 1 |
| Yi, HS | 1 |
| Yoo, YJ | 1 |
| Je, J | 1 |
| Suh, SJ | 1 |
| Jung, YK | 1 |
| Kim, JH | 1 |
| Seo, YS | 1 |
| Yim, HJ | 1 |
| Jeong, WI | 1 |
| Yeon, JE | 1 |
| Um, SH | 1 |
| Byun, KS | 1 |
| Paka, L | 1 |
| Smith, DE | 1 |
| Jung, D | 1 |
| McCormack, S | 1 |
| Zhou, P | 1 |
| Duan, B | 1 |
| Li, JS | 1 |
| Shi, J | 1 |
| Hao, YJ | 1 |
| Jiang, K | 1 |
| Yamin, M | 1 |
| Goldberg, ID | 1 |
| Narayan, P | 1 |
| Liu, J | 1 |
| Yang, P | 1 |
| Zuo, G | 1 |
| He, S | 1 |
| Tan, W | 1 |
| Zhang, X | 1 |
| Su, C | 1 |
| Zhao, L | 1 |
| Wei, L | 1 |
| Chen, Y | 2 |
| Ruan, X | 1 |
| Cansanção, K | 1 |
| Silva Monteiro, L | 1 |
| Carvalho Leite, N | 1 |
| Dávalos, A | 1 |
| Tavares do Carmo, MDG | 1 |
| Arantes Ferreira Peres, W | 1 |
| Kwan, HY | 1 |
| Niu, X | 1 |
| Dai, W | 1 |
| Tong, T | 1 |
| Chao, X | 1 |
| Su, T | 1 |
| Chan, CL | 1 |
| Lee, KC | 1 |
| Fu, X | 1 |
| Yi, H | 1 |
| Yu, H | 1 |
| Li, T | 1 |
| Tse, AK | 1 |
| Fong, WF | 1 |
| Pan, SY | 1 |
| Lu, A | 1 |
| Yu, ZL | 1 |
| Chong, LW | 1 |
| Hsu, YC | 1 |
| Lee, TF | 1 |
| Lin, Y | 1 |
| Chiu, YT | 1 |
| Yang, KC | 1 |
| Wu, JC | 1 |
| Huang, YT | 1 |
| Murakami, H | 1 |
| Yamanishi, H | 1 |
| Abe, M | 1 |
| Onji, M | 1 |
| Miura, K | 1 |
| Yang, L | 1 |
| van Rooijen, N | 1 |
| Brenner, DA | 1 |
| Ohnishi, H | 1 |
| Seki, E | 1 |
| Cabré, E | 1 |
| Hernández-Pérez, JM | 1 |
| Fluvià, L | 1 |
| Pastor, C | 1 |
| Corominas, A | 1 |
| Gassull, MA | 1 |
| Abergel, A | 1 |
| Sapin, V | 1 |
| Dif, N | 1 |
| Chassard, C | 1 |
| Darcha, C | 1 |
| Marcand-Sauvant, J | 1 |
| Gaillard-Martinie, B | 1 |
| Rock, E | 1 |
| Dechelotte, P | 1 |
| Sauvant, P | 1 |
| Greco, AV | 1 |
| Mingrone, G | 1 |
| Gasbarrini, G | 1 |
| Brivet, M | 1 |
| Tardieu, M | 1 |
| Khellaf, A | 1 |
| Boutron, A | 1 |
| Rocchiccioli, F | 1 |
| Haengeli, CA | 1 |
| Lemonnier, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Statins for Prevention of Disease Progression and Hospitalization in Liver Cirrhosis: A Multi-center, Randomized, Double Blind, Placebo-controlled Trial. The STATLiver Trial[NCT04072601] | Phase 4 | 78 participants (Actual) | Interventional | 2019-11-08 | Terminated (stopped due to Study part one completed) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for palmitic acid and Cirrhosis, Liver
| Article | Year |
|---|---|
Rapid alternative absorption of dietary long-chain fatty acids with upregulation of intestinal glycosylated CD36 in liver cirrhosis.
Topics: Aged; Caprylates; CD36 Antigens; Dietary Fats; Female; Glucagon-Like Peptide 2; Glycosylation; Human | 2012 |
16 other studies available for palmitic acid and Cirrhosis, Liver
| Article | Year |
|---|---|
Auranofin attenuates hepatic steatosis and fibrosis in nonalcoholic fatty liver disease via NRF2 and NF- κB signaling pathways.
Topics: Animals; Antioxidants; Auranofin; Collagen; Endothelin-1; Fibronectins; Humans; Liver; Liver Cirrhos | 2022 |
Metabolomic analysis shows dysregulation in amino acid and NAD+ metabolism in palmitate treated hepatocytes and plasma of non-alcoholic fatty liver disease spectrum.
Topics: Amino Acids; Hepatocytes; Humans; Kynurenine; Liver; Liver Cirrhosis; NAD; Non-alcoholic Fatty Liver | 2023 |
Saturated Fat-Mediated Upregulation of IL-32 and CCL20 in Hepatocytes Contributes to Higher Expression of These Fibrosis-Driving Molecules in MASLD.
Topics: Carcinoma, Hepatocellular; Chemokine CCL20; Chemokines; Fats, Unsaturated; Fatty Liver; Hepatocytes; | 2023 |
The mechanism of increased intestinal palmitic acid absorption and its impact on hepatic stellate cell activation in nonalcoholic steatohepatitis.
Topics: Animals; Chylomicrons; Hepatic Stellate Cells; Humans; Intestinal Absorption; Liver; Liver Cirrhosis | 2021 |
Exosomes derived from palmitic acid-treated hepatocytes induce fibrotic activation of hepatic stellate cells.
Topics: Animals; Cell Line, Tumor; Exosomes; Gene Expression Profiling; Hepatic Stellate Cells; Hepatocytes; | 2017 |
Anti-steatotic and anti-fibrotic effects of the KCa3.1 channel inhibitor, Senicapoc, in non-alcoholic liver disease.
Topics: Acetamides; Animals; Apoptosis; Biomarkers, Tumor; Diet, High-Fat; Fibrosis; Gene Expression Regulat | 2017 |
Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress.
Topics: Actins; Animals; CD36 Antigens; Cell Line; Desmin; Diet, High-Fat; Gene Expression Regulation; Hepat | 2018 |
Advanced Liver Fibrosis Is Independently Associated with Palmitic Acid and Insulin Levels in Patients with Non-Alcoholic Fatty Liver Disease.
Topics: Acetyltransferases; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Delta-5 Fatty Acid Desa | 2018 |
Lipidomic-based investigation into the regulatory effect of Schisandrin B on palmitic acid level in non-alcoholic steatotic livers.
Topics: Animals; Cyclooctanes; Diet, High-Fat; Disease Models, Animal; Fasting; Fatty Acid Synthases; Fatty | 2015 |
Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells.
Topics: Actins; Animals; Choline; Collagen Type I; Culture Media, Conditioned; Diet; Fatty Acids, Monounsatu | 2015 |
Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice.
Topics: Animals; Caspase 1; Fatty Liver; Hepatic Stellate Cells; Inflammasomes; Interleukin-1alpha; Interleu | 2013 |
[DIET IN DISORDERS OF LIPID METABOLISM].
Topics: Diabetes Mellitus; Diet; Diet Therapy; Fats, Unsaturated; Fatty Acids; Fatty Acids, Essential; Human | 1963 |
Absorption and transport of dietary long-chain fatty acids in cirrhosis: a stable-isotope-tracing study.
Topics: Aged; Area Under Curve; Ascites; Breath Tests; Carbon Isotopes; Case-Control Studies; Chylomicrons; | 2005 |
Growth arrest and decrease of alpha-SMA and type I collagen expression by palmitic acid in the rat hepatic stellate cell line PAV-1.
Topics: Actins; Animals; Cell Cycle; Cell Line; Cell Proliferation; Collagen Type I; Liver; Liver Cirrhosis; | 2006 |
Free fatty acid analysis in ascitic fluid improves diagnosis in malignant abdominal tumors.
Topics: Adult; Aged; Albumins; Arachidonic Acid; Ascitic Fluid; Carcinoma, Hepatocellular; Fatty Acids, None | 1995 |
Riboflavin responsive ethylmalonic-adipic aciduria in a 9-month-old boy with liver cirrhosis, myopathy and encephalopathy.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Adipates; Brain Diseases; Fatty Acids; Female; Fibroblasts; Humans | 1991 |