palmitic acid has been researched along with Bipolar Disorder in 3 studies
Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lithium and certain anticonvulsants, including carbamazepine and valproic acid, are effective antimanic drugs for treating bipolar disorder, but their mechanisms of action remain uncertain." | 8.81 | Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder? ( Bosetti, F; Rapoport, SI, 2002) |
| "Several drugs used to treat bipolar disorder (lithium and carbamazepine), when administered chronically to rats, reduce the turnover of arachidonic acid, but not docosahexaenoic acid, in brain phospholipids by decreasing the activity of an arachidonic acid-selective phospholipase A(2)." | 7.73 | Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl-CoA by brain microsomal long-chain fatty acyl-CoA synthetases: relevance to bipolar disorder. ( Bazinet, RP; Rapoport, SI; Rosenberger, TA; Weis, MT, 2006) |
| "Lithium and certain anticonvulsants, including carbamazepine and valproic acid, are effective antimanic drugs for treating bipolar disorder, but their mechanisms of action remain uncertain." | 4.81 | Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder? ( Bosetti, F; Rapoport, SI, 2002) |
| "Several drugs used to treat bipolar disorder (lithium and carbamazepine), when administered chronically to rats, reduce the turnover of arachidonic acid, but not docosahexaenoic acid, in brain phospholipids by decreasing the activity of an arachidonic acid-selective phospholipase A(2)." | 3.73 | Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl-CoA by brain microsomal long-chain fatty acyl-CoA synthetases: relevance to bipolar disorder. ( Bazinet, RP; Rapoport, SI; Rosenberger, TA; Weis, MT, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McNamara, RK | 1 |
| Jandacek, R | 1 |
| Rider, T | 1 |
| Tso, P | 1 |
| Stanford, KE | 1 |
| Hahn, CG | 1 |
| Richtand, NM | 1 |
| Bazinet, RP | 1 |
| Weis, MT | 1 |
| Rapoport, SI | 2 |
| Rosenberger, TA | 1 |
| Bosetti, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prophylactic Trial of Omega-3 Polyunsaturated Fatty Acids in Bipolar Disorder[NCT04210804] | Phase 2 | 80 participants (Actual) | Interventional | 2014-04-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for palmitic acid and Bipolar Disorder
| Article | Year |
|---|---|
Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder?
Topics: Animals; Anticonvulsants; Antimanic Agents; Arachidonic Acid; Bipolar Disorder; Brain; Brain Chemist | 2002 |
2 other studies available for palmitic acid and Bipolar Disorder
| Article | Year |
|---|---|
Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder.
Topics: Adult; Alcoholism; Antipsychotic Agents; Arachidonic Acid; Autopsy; Bipolar Disorder; Cerebral Corte | 2008 |
Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl-CoA by brain microsomal long-chain fatty acyl-CoA synthetases: relevance to bipolar disorder.
Topics: Acyl Coenzyme A; Animals; Antimanic Agents; Arachidonic Acid; Bipolar Disorder; Brain; Coenzyme A Li | 2006 |