palmitic acid has been researched along with Adrenoleukodystrophy in 8 studies
Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Adrenoleukodystrophy: An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This disease occurs almost exclusively in the males. Clinical features include the childhood onset of ATAXIA; NEUROBEHAVIORAL MANIFESTATIONS; HYPERPIGMENTATION; ADRENAL INSUFFICIENCY; SEIZURES; MUSCLE SPASTICITY; and DEMENTIA. The slowly progressive adult form is called adrenomyeloneuropathy. The defective gene ABCD1 is located at Xq28, and encodes the adrenoleukodystrophy protein (ATP-BINDING CASSETTE TRANSPORTERS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although plasma very-long-chain fatty acid profile suggested X-linked adrenoleukodystrophy, marked reduction in fibroblast lignoceric acid oxidation and the presence of cytosolic catalase were consistent with Zellweger syndrome (ZS)." | 3.69 | Late-onset generalized disorder of peroxisomes. ( Burdette, DE; Fink, JK; Kremser, K; Pahan, K; Singh, I; Stanley, W, 1996) |
| "Very long chain fatty acids (lignoceric acid) are oxidized in peroxisomes and pathognomonic amounts of these fatty acids accumulate in X-adrenoleukodystrophy (X-ALD) due to a defect in their oxidation." | 3.67 | Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency. ( Bhushan, A; Contreras, M; Lazo, O; Singh, I; Stanley, W, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, I | 5 |
| Lazo, O | 4 |
| Kremser, K | 2 |
| Pahan, K | 2 |
| Dhaunsi, GS | 1 |
| Ozand, P | 1 |
| Burdette, DE | 1 |
| Fink, JK | 1 |
| Stanley, W | 3 |
| Dvoráková, L | 1 |
| Storkánová, G | 1 |
| Unterrainer, G | 1 |
| Hujová, J | 1 |
| Kmoch, S | 1 |
| Zeman, J | 1 |
| Hrebícek, M | 1 |
| Berger, J | 1 |
| Reubsaet, FA | 1 |
| Veerkamp, JH | 1 |
| Brückwilder, ML | 1 |
| Trijbels, JM | 1 |
| Hashimoto, T | 1 |
| Monnens, LA | 1 |
| Contreras, M | 2 |
| Yoshida, Y | 1 |
| Singh, AK | 1 |
| Weise, M | 1 |
| Bhushan, A | 1 |
| Sacktor, NC | 1 |
| Griffin, J | 1 |
| Moser, AB | 1 |
| Moser, HW | 1 |
8 other studies available for palmitic acid and Adrenoleukodystrophy
| Article | Year |
|---|---|
Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain.
Topics: Adrenoleukodystrophy; Animals; Antibodies; Brain Chemistry; Coenzyme A Ligases; Fatty Acids; Liver; | 1993 |
Phytanic acid alpha-oxidation. Differential subcellular localization in rat and human tissues and its inhibition by nycodenz.
Topics: Adrenoleukodystrophy; Animals; Cell Fractionation; Cells, Cultured; Centrifugation, Density Gradient | 1993 |
Late-onset generalized disorder of peroxisomes.
Topics: Adrenoleukodystrophy; Adult; Catalase; Fatty Acids; Genetic Linkage; Humans; Male; Microbodies; Oxid | 1996 |
Eight novel ABCD1 gene mutations and three polymorphisms in patients with X-linked adrenoleukodystrophy: The first polymorphism causing an amino acid exchange.
Topics: 5' Untranslated Regions; Adolescent; Adrenoleukodystrophy; Adult; Alleles; Amino Acid Motifs; ATP Bi | 2001 |
Immunochemical and biochemical studies of fatty acid oxidation in fibroblasts of Zellweger and X-linked adrenoleukodystrophy patients.
Topics: Acetyl-CoA C-Acyltransferase; Acyl-CoA Oxidase; Adrenoleukodystrophy; Fatty Acids; Fibroblasts; Huma | 1991 |
Cellular oxidation of lignoceric acid is regulated by the subcellular localization of lignoceroyl-CoA ligases.
Topics: Adrenoleukodystrophy; Cell Fractionation; Cell Line; Coenzyme A Ligases; Diffuse Cerebral Sclerosis | 1990 |
Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency.
Topics: Adrenoleukodystrophy; Animals; Coenzyme A Ligases; Diffuse Cerebral Sclerosis of Schilder; Fatty Aci | 1989 |
Effects of subperineurial injections of very-long-chain and medium-chain fatty acids into rat sciatic nerve.
Topics: Adrenoleukodystrophy; Animals; Cholesterol Esters; Diffuse Cerebral Sclerosis of Schilder; Disease M | 1986 |