palmidrol has been researched along with Spinal Cord Injuries in 13 studies
palmidrol: a cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection
palmitoyl ethanolamide : An N-(long-chain-acyl)ethanolamine that is the ethanolamide of palmitic (hexadecanoic) acid.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We randomized 73 individuals with neuropathic pain due to SCI, of which 5 had a major protocol violation, and thus 68 were included in the primary analysis." | 2.82 | Ultramicronized palmitoylethanolamide in spinal cord injury neuropathic pain: a randomized, double-blind, placebo-controlled trial. ( Andresen, SR; Bach, FW; Biering-Sørensen, F; Bing, J; Finnerup, NB; Hagen, EM; Hansen, RM; Johannesen, IL; Nielsen, JF; Rice, ASC, 2016) |
| "Inflammation is fundamentally a protective cellular response aimed at removing injurious stimuli and initiating the healing process." | 2.52 | N-Palmitoylethanolamine and Neuroinflammation: a Novel Therapeutic Strategy of Resolution. ( Barbierato, M; Bruschetta, G; Cuzzocrea, S; Facci, L; Giusti, P; Impellizzeri, D; Skaper, SD; Zusso, M, 2015) |
| "in spinal cord and traumatic brain injuries and in age-related pathological processes." | 2.49 | Palmitoylethanolamide in homeostatic and traumatic central nervous system injuries. ( Cuzzocrea, S; Esposito, E, 2013) |
| "The mechanisms involved in neuropathic pain are complex and involve both peripheral and central phenomena." | 2.48 | Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system. ( Przewlocka, B; Starowicz, K, 2012) |
| "Spinal cord trauma was induced in mice by the application of vascular clips to the dura via a four-level T5-T8 laminectomy." | 1.37 | Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury. ( Cuzzocrea, S; Di Paola, R; Esposito, E; Galuppo, M; Genovese, T; Mazzon, E; Paterniti, I, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, H | 1 |
| Xiang, D | 1 |
| Liu, X | 1 |
| Xiang, L | 1 |
| Paterniti, I | 4 |
| Impellizzeri, D | 5 |
| Di Paola, R | 3 |
| Navarra, M | 1 |
| Cuzzocrea, S | 9 |
| Esposito, E | 7 |
| Skaper, SD | 1 |
| Facci, L | 1 |
| Barbierato, M | 1 |
| Zusso, M | 1 |
| Bruschetta, G | 3 |
| Giusti, P | 1 |
| Siracusa, R | 2 |
| Cordaro, M | 2 |
| Crupi, R | 3 |
| Andresen, SR | 1 |
| Bing, J | 1 |
| Hansen, RM | 1 |
| Biering-Sørensen, F | 1 |
| Johannesen, IL | 1 |
| Hagen, EM | 1 |
| Rice, ASC | 1 |
| Nielsen, JF | 1 |
| Bach, FW | 1 |
| Finnerup, NB | 1 |
| Garcia-Ovejero, D | 1 |
| Arevalo-Martin, A | 1 |
| Petrosino, S | 1 |
| Docagne, F | 1 |
| Hagen, C | 1 |
| Bisogno, T | 1 |
| Watanabe, M | 1 |
| Guaza, C | 1 |
| Di Marzo, V | 1 |
| Molina-Holgado, E | 1 |
| Solorzano, C | 1 |
| Zhu, C | 1 |
| Battista, N | 1 |
| Astarita, G | 1 |
| Lodola, A | 1 |
| Rivara, S | 1 |
| Mor, M | 1 |
| Russo, R | 1 |
| Maccarrone, M | 1 |
| Antonietti, F | 1 |
| Duranti, A | 1 |
| Tontini, A | 1 |
| Tarzia, G | 1 |
| Piomelli, D | 2 |
| Mazzon, E | 2 |
| Genovese, T | 2 |
| Galuppo, M | 1 |
| Starowicz, K | 1 |
| Przewlocka, B | 1 |
| Morabito, R | 1 |
| Campolo, M | 1 |
| Meli, R | 1 |
| Bramanti, P | 1 |
| Calignano, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Postoperative Pain and Inflammation Following Below Knee Fracture Fixation: A Pilot Study.[NCT05317676] | Phase 2 | 0 participants (Actual) | Interventional | 2023-05-31 | Withdrawn (stopped due to Sponsor suspending temporarily.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for palmidrol and Spinal Cord Injuries
| Article | Year |
|---|---|
N-Palmitoylethanolamine and Neuroinflammation: a Novel Therapeutic Strategy of Resolution.
Topics: Administration, Oral; Amides; Amidohydrolases; Animals; Anti-Inflammatory Agents; Antidepressive Age | 2015 |
Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system.
Topics: Amides; Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; Behavior; Benzamides; Carbama | 2012 |
Palmitoylethanolamide in homeostatic and traumatic central nervous system injuries.
Topics: Amides; Animals; Brain Injuries; Endocannabinoids; Ethanolamines; Homeostasis; Humans; Neuroglia; Ne | 2013 |
1 trial available for palmidrol and Spinal Cord Injuries
| Article | Year |
|---|---|
Ultramicronized palmitoylethanolamide in spinal cord injury neuropathic pain: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Amides; Analgesics; Analysis of Variance; Double-Blind Method; Ethanolamines; Female; F | 2016 |
9 other studies available for palmidrol and Spinal Cord Injuries
| Article | Year |
|---|---|
PPARα agonist relieves spinal cord injury in rats by activating Nrf2/HO-1 via the Raf-1/MEK/ERK pathway.
Topics: Amides; Animals; Ethanolamines; Heme Oxygenase (Decyclizing); Male; MAP Kinase Signaling System; NF- | 2021 |
A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury.
Topics: Amides; Animals; Blotting, Western; Cell Survival; Coloring Agents; Cyclooxygenase 2; Drug Combinati | 2013 |
The Association of Palmitoylethanolamide with Luteolin Decreases Autophagy in Spinal Cord Injury.
Topics: Amides; Animals; Autophagy; Beclin-1; DNA-Binding Proteins; Drug Combinations; Ethanolamines; Fluore | 2016 |
N-Palmitoylethanolamine-Oxazoline as a New Therapeutic Strategy to Control Neuroinflammation: Neuroprotective Effects in Experimental Models of Spinal Cord and Brain Injury.
Topics: Amides; Animals; Brain Injuries; Cytokines; Ethanolamines; Glial Fibrillary Acidic Protein; Inflamma | 2017 |
The endocannabinoid system is modulated in response to spinal cord injury in rats.
Topics: Amides; Amidohydrolases; Animals; Arachidonic Acids; Astrocytes; Cannabinoid Receptor Modulators; En | 2009 |
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.
Topics: Amides; Amidohydrolases; Animals; Anti-Inflammatory Agents; Butyrates; Carrageenan; Catalytic Domain | 2009 |
Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Cell Degranulation; Chymases; | 2011 |
Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Endocannabinoids; Ethanolamines; Mice; Mic | 2013 |
Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury.
Topics: Amides; Animals; Endocannabinoids; Ethanolamines; Male; Mice; Motor Skills; Nitric Oxide Synthase Ty | 2008 |