Page last updated: 2024-11-02

palmidrol and Schizophrenia

palmidrol has been researched along with Schizophrenia in 5 studies

palmidrol: a cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection
palmitoyl ethanolamide : An N-(long-chain-acyl)ethanolamine that is the ethanolamide of palmitic (hexadecanoic) acid.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"This 8-week (trial timepoints: baseline, week 4, week 8), double-blind, placebo-controlled clinical trial randomized patients with schizophrenia in a 1:1 ratio to compare the efficacy and safety of 600 mg twice a day of PEA and matched placebo alongside a stable dose of risperidone."9.51Adjuvant palmitoylethanolamide therapy with risperidone improves negative symptoms in patients with schizophrenia: A randomized, double-blinded, placebo-controlled trial. ( Akhondzadeh, S; Bagheri, S; Khodaei Ardakani, MR; Moradi, K; Namaei, P; Salehi, A; TaghaviZanjani, F, 2022)
"In agreement with the neurodevelopmental hypothesis of schizophrenia, prenatal exposure of rats to the antimitotic agent methylazoxymethanol acetate (MAM) at gestational day 17 produced long-lasting behavioral alterations such as social withdrawal and cognitive impairment in the social interaction test and in the novel object recognition test, respectively."7.91Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia. ( Babinska, Z; Bari, M; D'Addario, C; Di Bartolomeo, M; Di Marco, R; Di Marzo, V; Drago, F; Drazanova, E; Giurdanella, G; Iannotti, FA; Maccarrone, M; Mechoulam, R; Micale, V; Pekarik, V; Piscitelli, F; Ruda-Kucerova, J; Salomone, S; Starcuk, Z; Stark, T; Sulcova, A; Wotjak, CT, 2019)
"This 8-week (trial timepoints: baseline, week 4, week 8), double-blind, placebo-controlled clinical trial randomized patients with schizophrenia in a 1:1 ratio to compare the efficacy and safety of 600 mg twice a day of PEA and matched placebo alongside a stable dose of risperidone."5.51Adjuvant palmitoylethanolamide therapy with risperidone improves negative symptoms in patients with schizophrenia: A randomized, double-blinded, placebo-controlled trial. ( Akhondzadeh, S; Bagheri, S; Khodaei Ardakani, MR; Moradi, K; Namaei, P; Salehi, A; TaghaviZanjani, F, 2022)
"We analyzed plasma concentrations of anandamide, 2-arachidonoyl-sn-glycerol, palmitoylethanolamide and oleoylethanolamide from 25 twin pairs discordant for schizophrenia, six discordant for bipolar disorder and eight healthy twin pairs to determine hereditary traits."3.91Familial abnormalities of endocannabinoid signaling in schizophrenia. ( Hellmich, M; Koethe, D; Leweke, FM; Meyer-Lindenberg, A; Mueller, JK; Pahlisch, F; Piomelli, D; Rohleder, C; Torrey, EF, 2019)
"In agreement with the neurodevelopmental hypothesis of schizophrenia, prenatal exposure of rats to the antimitotic agent methylazoxymethanol acetate (MAM) at gestational day 17 produced long-lasting behavioral alterations such as social withdrawal and cognitive impairment in the social interaction test and in the novel object recognition test, respectively."3.91Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia. ( Babinska, Z; Bari, M; D'Addario, C; Di Bartolomeo, M; Di Marco, R; Di Marzo, V; Drago, F; Drazanova, E; Giurdanella, G; Iannotti, FA; Maccarrone, M; Mechoulam, R; Micale, V; Pekarik, V; Piscitelli, F; Ruda-Kucerova, J; Salomone, S; Starcuk, Z; Stark, T; Sulcova, A; Wotjak, CT, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Salehi, A1
Namaei, P1
TaghaviZanjani, F1
Bagheri, S1
Moradi, K1
Khodaei Ardakani, MR1
Akhondzadeh, S1
Koethe, D2
Pahlisch, F2
Hellmich, M2
Rohleder, C1
Mueller, JK1
Meyer-Lindenberg, A1
Torrey, EF1
Piomelli, D3
Leweke, FM3
Stark, T1
Ruda-Kucerova, J1
Iannotti, FA1
D'Addario, C1
Di Marco, R1
Pekarik, V1
Drazanova, E1
Piscitelli, F1
Bari, M1
Babinska, Z1
Giurdanella, G1
Di Bartolomeo, M1
Salomone, S1
Sulcova, A1
Maccarrone, M1
Wotjak, CT1
Starcuk, Z1
Drago, F1
Mechoulam, R1
Di Marzo, V1
Micale, V1
Muhl, D1
Gerth, CW1
Hoyer, C1
Klosterkötter, J1
Giuffrida, A1
Wurster, U1
Emrich, HM1

Trials

2 trials available for palmidrol and Schizophrenia

ArticleYear
Adjuvant palmitoylethanolamide therapy with risperidone improves negative symptoms in patients with schizophrenia: A randomized, double-blinded, placebo-controlled trial.
    Psychiatry research, 2022, Volume: 316

    Topics: Amides; Antipsychotic Agents; Basal Ganglia Diseases; Double-Blind Method; Drug Therapy, Combination

2022
Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia.
    Translational psychiatry, 2012, Mar-20, Volume: 2

    Topics: Acute Disease; Adult; Amides; Amisulpride; Antipsychotic Agents; Arachidonic Acids; Cannabidiol; Dou

2012

Other Studies

3 other studies available for palmidrol and Schizophrenia

ArticleYear
Familial abnormalities of endocannabinoid signaling in schizophrenia.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2019, Volume: 20, Issue:2

    Topics: Adult; Amides; Arachidonic Acids; Bipolar Disorder; Endocannabinoids; Ethanolamines; Female; Genetic

2019
Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia.
    Neuropharmacology, 2019, 03-01, Volume: 146

    Topics: Amides; Animals; Arachidonic Acids; Cannabidiol; Disease Models, Animal; Endocannabinoids; Ethanolam

2019
Elevated endogenous cannabinoids in schizophrenia.
    Neuroreport, 1999, Jun-03, Volume: 10, Issue:8

    Topics: Adult; Amides; Arachidonic Acids; Cannabinoids; Chromatography, High Pressure Liquid; Endocannabinoi

1999