palmidrol has been researched along with Pain, Chronic in 22 studies
palmidrol: a cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection
palmitoyl ethanolamide : An N-(long-chain-acyl)ethanolamine that is the ethanolamide of palmitic (hexadecanoic) acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic pain is a major source of morbidity for which there are limited effective treatments." | 3.01 | Palmitoylethanolamide in the Treatment of Chronic Pain: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials. ( Bornemann-Cimenti, H; Brenna, CTA; Klivinyi, C; Lang-Illievich, K; Lasser, C; Szilagyi, IS, 2023) |
| " PEA (600 mg) was administered twice daily for 3 weeks followed by single daily dosing for 4 weeks, in addition to standard analgesic therapies or as single therapy." | 2.77 | Palmitoylethanolamide in the treatment of chronic pain caused by different etiopathogenesis. ( Di Paolo, A; Gatti, A; Gianfelice, V; Lazzari, M; Sabato, AF; Sabato, E, 2012) |
| "The population will be patients who have chronic pain, the intervention will be the administration of PEA alone or in combination with other drugs for the pain management; the comparison will be the standard therapy in accordance with the current guidelines for the treatment of pain." | 2.61 | Clinical applications of palmitoylethanolamide in pain management: protocol for a scoping review. ( Alfieri, A; Aurilio, C; Barbarisi, M; Fiore, M; Pace, MC; Passavanti, MB; Piccinno, G; Pota, V; Sansone, P, 2019) |
| "The terms chronic pain, neuropathic pain, and micronized and ultra-micronized PEA were used for the search." | 2.53 | Palmitoylethanolamide, a Special Food for Medical Purposes, in the Treatment of Chronic Pain: A Pooled Data Meta-analysis. ( Cenacchi, T; Fusco, M; Paladini, A; Piroli, A; Schievano, C; Varrassi, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 18 (81.82) | 24.3611 |
| 2020's | 4 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Indraccolo, U | 1 |
| Favilli, A | 1 |
| Dell'Anna, A | 1 |
| Di Francesco, A | 1 |
| Dionisi, B | 1 |
| Giugliano, E | 2 |
| Murina, F | 1 |
| Stocco, E | 1 |
| Lang-Illievich, K | 1 |
| Klivinyi, C | 1 |
| Lasser, C | 1 |
| Brenna, CTA | 1 |
| Szilagyi, IS | 1 |
| Bornemann-Cimenti, H | 1 |
| Cervigni, M | 1 |
| Nasta, L | 1 |
| Schievano, C | 2 |
| Lampropoulou, N | 1 |
| Ostardo, E | 1 |
| Kiso, T | 1 |
| Watabiki, T | 1 |
| Sekizawa, T | 1 |
| Mabou Tagne, A | 1 |
| Fotio, Y | 1 |
| Lin, L | 1 |
| Squire, E | 1 |
| Ahmed, F | 1 |
| Rashid, TI | 1 |
| Karimian Azari, E | 1 |
| Piomelli, D | 1 |
| Giammusso, B | 1 |
| Di Mauro, R | 1 |
| Bernardini, R | 1 |
| Stensson, N | 2 |
| Ghafouri, B | 4 |
| Gerdle, B | 4 |
| Ghafouri, N | 4 |
| Artukoglu, BB | 1 |
| Beyer, C | 1 |
| Zuloff-Shani, A | 1 |
| Brener, E | 1 |
| Bloch, MH | 1 |
| Germini, F | 2 |
| Coerezza, A | 2 |
| Andreinetti, L | 2 |
| Nobili, A | 2 |
| Rossi, PD | 2 |
| Mari, D | 2 |
| Guyatt, G | 1 |
| Marcucci, M | 2 |
| Passavanti, MB | 1 |
| Alfieri, A | 1 |
| Pace, MC | 1 |
| Pota, V | 1 |
| Sansone, P | 1 |
| Piccinno, G | 1 |
| Barbarisi, M | 1 |
| Aurilio, C | 1 |
| Fiore, M | 1 |
| De Leo, V | 1 |
| Cagnacci, A | 1 |
| Cappelli, V | 1 |
| Biasioli, A | 1 |
| Leonardi, D | 1 |
| Seracchioli, R | 1 |
| Cagnazzo, E | 1 |
| Soave, I | 2 |
| Lo Monte, G | 2 |
| Wenger, JM | 1 |
| Marci, R | 2 |
| Larsson, B | 3 |
| Fowler, CJ | 3 |
| Turkina, MV | 2 |
| Karlsson, L | 2 |
| Di Cesare Mannelli, L | 1 |
| Corti, F | 1 |
| Micheli, L | 1 |
| Zanardelli, M | 1 |
| Ghelardini, C | 1 |
| Caruso, S | 1 |
| Iraci Sareri, M | 1 |
| Casella, E | 1 |
| Ventura, B | 1 |
| Fava, V | 1 |
| Cianci, A | 1 |
| Paladini, A | 1 |
| Fusco, M | 1 |
| Cenacchi, T | 1 |
| Piroli, A | 1 |
| Varrassi, G | 1 |
| Silva, M | 1 |
| Martins, D | 1 |
| Charrua, A | 1 |
| Piscitelli, F | 1 |
| Tavares, I | 1 |
| Morgado, C | 1 |
| Di Marzo, V | 1 |
| Bellintani, L | 1 |
| Gatti, A | 1 |
| Lazzari, M | 1 |
| Gianfelice, V | 1 |
| Di Paolo, A | 1 |
| Sabato, E | 1 |
| Sabato, AF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Postoperative Pain and Inflammation Following Below Knee Fracture Fixation: A Pilot Study.[NCT05317676] | Phase 2 | 0 participants (Actual) | Interventional | 2023-05-31 | Withdrawn (stopped due to Sponsor suspending temporarily.) | ||
| N-of-1 Randomised Trials to Assess the Efficacy of Ultra-micronized Palmitoylethanolamide (Um-PEA) in Geriatric Patients With Chronic Pain[NCT02699281] | Phase 4 | 11 participants (Actual) | Interventional | 2015-10-31 | Completed | ||
| The Effects (Pain, Function, Biochemistry and Psychological Factors) of Two Different Home-exercise Programmes on Women Suffering Long Term Nack/Shoulder Muscle Pain[NCT01876680] | Phase 2 | 57 participants (Actual) | Interventional | 2009-09-30 | Completed | ||
| The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced Hyperalgesia[NCT04662827] | 14 participants (Actual) | Interventional | 2020-02-09 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for palmidrol and Pain, Chronic
| Article | Year |
|---|---|
Looking for Responders among Women with Chronic Pelvic Pain Treated with a Comicronized Formulation of Micronized Palmitoylethanolamide and Polydatin.
Topics: Amides; Chronic Pain; Dysmenorrhea; Endometriosis; Ethanolamines; Female; Glucosides; Humans; Palmit | 2022 |
Palmitoylethanolamide in the Treatment of Chronic Pain: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials.
Topics: Amides; Analgesics; Chronic Pain; Humans; Quality of Life; Randomized Controlled Trials as Topic | 2023 |
Efficacy of Palmitoylethanolamide for Pain: A Meta-Analysis.
Topics: Acute Pain; Amides; Analgesics; Chronic Pain; Ethanolamines; Humans; Outcome Assessment, Health Care | 2017 |
Clinical applications of palmitoylethanolamide in pain management: protocol for a scoping review.
Topics: Amides; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Ethanolamines; Humans; Pain Managemen | 2019 |
Palmitoylethanolamide, a Special Food for Medical Purposes, in the Treatment of Chronic Pain: A Pooled Data Meta-analysis.
Topics: Adult; Amides; Analgesics; Chemistry, Pharmaceutical; Chronic Pain; Clinical Trials as Topic; Ethano | 2016 |
7 trials available for palmidrol and Pain, Chronic
| Article | Year |
|---|---|
The efficacy of an association of palmitoylethanolamide and alpha-lipoic acid in patients with chronic prostatitis/chronic pelvic pain syndrome: A randomized clinical trial.
Topics: Adult; Amides; Chronic Disease; Chronic Pain; Ethanolamines; Humans; Male; Middle Aged; Palmitic Aci | 2017 |
N-of-1 Randomized Trials of Ultra-Micronized Palmitoylethanolamide in Older Patients with Chronic Pain.
Topics: Aged; Aged, 80 and over; Amides; Analgesics; Chronic Pain; Ethanolamines; Female; Geriatric Assessme | 2017 |
[Administration of micronized palmitoylethanolamide (PEA)-transpolydatin in the treatment of chronic pelvic pain in women affected by endometriosis: preliminary results].
Topics: Adult; Amides; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Drug Combinations; Dysmenorrhe | 2013 |
Effects of two different specific neck exercise interventions on palmitoylethanolamide and stearoylethanolamide concentrations in the interstitium of the trapezius muscle in women with chronic neck shoulder pain.
Topics: Adult; Amides; Chronic Pain; Ethanolamines; Exercise Therapy; Female; Humans; Mass Spectrometry; Mic | 2014 |
Chronic pelvic pain, quality of life and sexual health of women treated with palmitoylethanolamide and α-lipoic acid.
Topics: Adolescent; Adult; Amides; Chronic Pain; Drug Therapy, Combination; Endometriosis; Ethanolamines; Fe | 2015 |
Efficacy of ultra-micronized palmitoylethanolamide (um-PEA) in geriatric patients with chronic pain: study protocol for a series of N-of-1 randomized trials.
Topics: Aged; Amides; Analgesics; Bayes Theorem; Chronic Pain; Clinical Protocols; Cross-Over Studies; Ethan | 2016 |
Palmitoylethanolamide in the treatment of chronic pain caused by different etiopathogenesis.
Topics: Adult; Aged; Aged, 80 and over; Amides; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Endoc | 2012 |
10 other studies available for palmidrol and Pain, Chronic
| Article | Year |
|---|---|
Micronized Palmitoylethanolamide-Polydatin Reduces the Painful Symptomatology in Patients with Interstitial Cystitis/Bladder Pain Syndrome.
Topics: Administration, Oral; Adult; Aged; Amides; Chronic Pain; Cystitis, Interstitial; Ethanolamines; Fema | 2019 |
ASP8477, a fatty acid amide hydrolase inhibitor, exerts analgesic effects in rat models of neuropathic and dysfunctional pain.
Topics: Amides; Amidohydrolases; Analgesics; Animals; Behavior, Animal; Brain; Chronic Pain; Disease Models, | 2020 |
Palmitoylethanolamide and hemp oil extract exert synergistic anti-nociceptive effects in mouse models of acute and chronic pain.
Topics: Acute Pain; Amides; Analgesics; Animals; Cannabis; Chronic Pain; Disease Models, Animal; Drug Synerg | 2021 |
Alterations of anti-inflammatory lipids in plasma from women with chronic widespread pain - a case control study.
Topics: Adult; Aged; Amides; Anti-Inflammatory Agents; Chronic Pain; Cytokines; Endocannabinoids; Ethanolami | 2017 |
Role of a natural integrator based on lipoic acid, palmitoiletanolamide and myrrh in the treatment of chronic pelvic pain and endometriosis.
Topics: Adult; Amides; Analgesics; Chronic Pain; Dietary Supplements; Endometriosis; Ethanolamines; Female; | 2019 |
The adjuvant use of N-palmitoylethanolamine and transpolydatin in the treatment of endometriotic pain.
Topics: Adult; Amides; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Contraceptives, Oral, Combined | 2013 |
Palmitoylethanolamide and stearoylethanolamide levels in the interstitium of the trapezius muscle of women with chronic widespread pain and chronic neck-shoulder pain correlate with pain intensity and sensitivity.
Topics: Adult; Aged; Amides; Chronic Pain; Endocannabinoids; Ethanolamines; Exercise; Female; Humans; Microd | 2013 |
Delay of morphine tolerance by palmitoylethanolamide.
Topics: Amides; Analgesics; Animals; Astrocytes; Chronic Pain; Drug Resistance; Ethanolamines; Male; Morphin | 2015 |
Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy.
Topics: Amides; Amidohydrolases; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Capsaicin; Chronic Pa | 2016 |
High levels of N-palmitoylethanolamide and N-stearoylethanolamide in microdialysate samples from myalgic trapezius muscle in women.
Topics: Adult; Amides; Chromatography, Liquid; Chronic Pain; Dialysis Solutions; Endocannabinoids; Ethanolam | 2011 |