Page last updated: 2024-11-02

palmidrol and Neurodegenerative Diseases

palmidrol has been researched along with Neurodegenerative Diseases in 10 studies

palmidrol: a cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection
palmitoyl ethanolamide : An N-(long-chain-acyl)ethanolamine that is the ethanolamide of palmitic (hexadecanoic) acid.

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research Excerpts

ExcerptRelevanceReference
"Here, we aim to investigate the effects of palmitoylethanolamide (PEA) combined with luteoline (PEA-LUT), an endocannabinoid with anti-inflammatory and neuroprotective effects, on behavior, cognition, and cortical activity in a sample of FTD patients."5.56Effects of Palmitoylethanolamide Combined with Luteoline on Frontal Lobe Functions, High Frequency Oscillations, and GABAergic Transmission in Patients with Frontotemporal Dementia. ( Assogna, M; Bonnì, S; Borghi, I; Caltagirone, C; Casula, EP; D'Acunto, A; Di Lorenzo, F; Koch, G; Martorana, A; Minei, M; Motta, C; Porrazzini, F; Samà, D, 2020)
" The properties of PEA, especially of its micronized or ultra-micronized forms maximizing bioavailability and efficacy, have sparked a series of innovative research to evaluate its possible application as therapeutic agent for neurodegenerative diseases."2.82Effects of Palmitoylethanolamide on Neurodegenerative Diseases: A Review from Rodents to Humans. ( Caltagirone, C; Cutuli, D; Landolfo, E; Petrosini, L, 2022)
"Here, we aim to investigate the effects of palmitoylethanolamide (PEA) combined with luteoline (PEA-LUT), an endocannabinoid with anti-inflammatory and neuroprotective effects, on behavior, cognition, and cortical activity in a sample of FTD patients."1.56Effects of Palmitoylethanolamide Combined with Luteoline on Frontal Lobe Functions, High Frequency Oscillations, and GABAergic Transmission in Patients with Frontotemporal Dementia. ( Assogna, M; Bonnì, S; Borghi, I; Caltagirone, C; Casula, EP; D'Acunto, A; Di Lorenzo, F; Koch, G; Martorana, A; Minei, M; Motta, C; Porrazzini, F; Samà, D, 2020)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (60.00)24.3611
2020's4 (40.00)2.80

Authors

AuthorsStudies
Landolfo, E1
Cutuli, D1
Petrosini, L1
Caltagirone, C2
Assogna, M2
Di Lorenzo, F2
Martorana, A2
Koch, G2
Casula, EP1
Borghi, I1
Bonnì, S1
Samà, D1
Motta, C1
D'Acunto, A1
Porrazzini, F1
Minei, M1
Petrosino, S2
Schiano Moriello, A1
Davis, MP1
Behm, B1
Mehta, Z1
Fernandez, C1
Fidaleo, M1
Fanelli, F1
Ceru, MP1
Moreno, S1
Mattace Raso, G1
Russo, R1
Calignano, A1
Meli, R1
Di Marzo, V1
Skaper, SD1
Facci, L1
Scuderi, C1
Steardo, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Postoperative Pain and Inflammation Following Below Knee Fracture Fixation: A Pilot Study.[NCT05317676]Phase 20 participants (Actual)Interventional2023-05-31Withdrawn (stopped due to Sponsor suspending temporarily.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for palmidrol and Neurodegenerative Diseases

ArticleYear
Effects of Palmitoylethanolamide on Neurodegenerative Diseases: A Review from Rodents to Humans.
    Biomolecules, 2022, 05-05, Volume: 12, Issue:5

    Topics: Amides; Animals; Ethanolamines; Humans; Neurodegenerative Diseases; Palmitic Acids; Rodentia

2022
Synaptic Effects of Palmitoylethanolamide in Neurodegenerative Disorders.
    Biomolecules, 2022, 08-22, Volume: 12, Issue:8

    Topics: Alzheimer Disease; Amides; Animals; Ethanolamines; Neurodegenerative Diseases; Palmitic Acids

2022
Palmitoylethanolamide: A Nutritional Approach to Keep Neuroinflammation within Physiological Boundaries-A Systematic Review.
    International journal of molecular sciences, 2020, Dec-15, Volume: 21, Issue:24

    Topics: Alzheimer Disease; Amides; Amyotrophic Lateral Sclerosis; Animals; Autism Spectrum Disorder; Endocan

2020
The Potential Benefits of Palmitoylethanolamide in Palliation: A Qualitative Systematic Review.
    The American journal of hospice & palliative care, 2019, Volume: 36, Issue:12

    Topics: Amides; Animals; Ethanolamines; Humans; Mental Disorders; Neurodegenerative Diseases; Pain; Palmitic

2019
Neuroprotective properties of peroxisome proliferator-activated receptor alpha (PPARα) and its lipid ligands.
    Current medicinal chemistry, 2014, Volume: 21, Issue:24

    Topics: Amides; Animals; Endocannabinoids; Ethanolamines; Humans; Ligands; Mental Disorders; Neurodegenerati

2014
Palmitoylethanolamide in CNS health and disease.
    Pharmacological research, 2014, Volume: 86

    Topics: Amides; Animals; Anti-Inflammatory Agents; Central Nervous System; Ethanolamines; Humans; Inflammati

2014
The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations.
    British journal of pharmacology, 2017, Volume: 174, Issue:11

    Topics: Amides; Analgesics; Animals; Anti-Inflammatory Agents; Chemistry, Pharmaceutical; Dietary Supplement

2017
Mast cell-glia axis in neuroinflammation and therapeutic potential of the anandamide congener palmitoylethanolamide.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2012, Dec-05, Volume: 367, Issue:1607

    Topics: Amides; Animals; Cell Communication; Central Nervous System; Endocannabinoids; Ethanolamines; Humans

2012

Other Studies

2 other studies available for palmidrol and Neurodegenerative Diseases

ArticleYear
Effects of Palmitoylethanolamide Combined with Luteoline on Frontal Lobe Functions, High Frequency Oscillations, and GABAergic Transmission in Patients with Frontotemporal Dementia.
    Journal of Alzheimer's disease : JAD, 2020, Volume: 76, Issue:4

    Topics: Activities of Daily Living; Aged; Amides; Cognition; Ethanolamines; Evoked Potentials, Motor; Female

2020
Neuroglial roots of neurodegenerative diseases: therapeutic potential of palmitoylethanolamide in models of Alzheimer's disease.
    CNS & neurological disorders drug targets, 2013, Feb-01, Volume: 12, Issue:1

    Topics: Alzheimer Disease; Amides; Animals; Cell Survival; Cells, Cultured; Disease Models, Animal; Endocann

2013