Page last updated: 2024-11-02

palmidrol and Edema

palmidrol has been researched along with Edema in 12 studies

palmidrol: a cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection
palmitoyl ethanolamide : An N-(long-chain-acyl)ethanolamine that is the ethanolamide of palmitic (hexadecanoic) acid.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
", PEA co-ultramicronized with the natural antioxidant quercetin (PEA-Q), administered orally in two different rat models of inflammatory and OA pain, namely carrageenan paw oedema and sodium monoiodoacetate (MIA)-induced OA."7.85A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models. ( Britti, D; Crupi, R; Cuzzocrea, S; Di Paola, R; Evangelista, M; Fusco, R; Gugliandolo, E; Impellizzeri, D; Morittu, VM; Schievano, C, 2017)
" The antiinflammatory activity of synthetic cannabinoid nabilone in the rat model of carrageenan-induced acute hindpaw inflammation was compared with that of the endocannabinoid palmitoylethanolamide and the nonsteroidal antiinflammatory drug indomethacin."7.71Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat. ( Colleoni, M; Conti, S; Costa, B; Giagnoni, G; Parolaro, D, 2002)
", PEA co-ultramicronized with the natural antioxidant quercetin (PEA-Q), administered orally in two different rat models of inflammatory and OA pain, namely carrageenan paw oedema and sodium monoiodoacetate (MIA)-induced OA."3.85A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models. ( Britti, D; Crupi, R; Cuzzocrea, S; Di Paola, R; Evangelista, M; Fusco, R; Gugliandolo, E; Impellizzeri, D; Morittu, VM; Schievano, C, 2017)
" Intraplantar injection of CAR led to a time-dependent development of peripheral inflammation, in terms of paw edema, cytokine release in paw exudates, nitrotyrosine formation, inducible nitric oxide synthase and cyclooxygenase-2 expression."3.83A new co-micronized composite containing palmitoylethanolamide and polydatin shows superior oral efficacy compared to their association in a rat paw model of carrageenan-induced inflammation. ( Bruschetta, G; Cordaro, M; Crupi, R; Cuzzocrea, S; Esposito, E; Gugliandolo, E; Impellizzeri, D; Siracusa, R, 2016)
" The antiinflammatory activity of synthetic cannabinoid nabilone in the rat model of carrageenan-induced acute hindpaw inflammation was compared with that of the endocannabinoid palmitoylethanolamide and the nonsteroidal antiinflammatory drug indomethacin."3.71Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat. ( Colleoni, M; Conti, S; Costa, B; Giagnoni, G; Parolaro, D, 2002)
" The lipidic nature and large particle size of PEA in the native state may limit its solubility and bioavailability when given orally, however."1.40Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain. ( Bruschetta, G; Cordaro, M; Crupi, R; Cuzzocrea, S; Esposito, E; Impellizzeri, D; Siracusa, R, 2014)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's5 (41.67)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Ardizzone, A1
Fusco, R2
Casili, G1
Lanza, M1
Impellizzeri, D5
Esposito, E5
Cuzzocrea, S6
Britti, D1
Crupi, R4
Gugliandolo, E2
Schievano, C1
Morittu, VM1
Evangelista, M1
Di Paola, R2
Bartolucci, ML1
Marini, I1
Bortolotti, F1
Bruschetta, G3
Portelli, M1
Militi, A1
Oteri, G1
Cordaro, M2
Siracusa, R2
Tronino, D1
Offerta, A1
Ostacolo, C1
Russo, R3
De Caro, C1
Calignano, A3
Puglia, C1
Blasi, P1
Lo Verme, J2
Fu, J1
Astarita, G1
La Rana, G2
Piomelli, D2
Jonsson, KO1
Persson, E1
Fowler, CJ1
D'Agostino, G1
Sasso, O1
Iacono, A1
Raso, GM1
Meli, R1
Dalle Carbonare, M1
Del Giudice, E1
Stecca, A1
Colavito, D1
Fabris, M1
D'Arrigo, A1
Bernardini, D1
Dam, M1
Leon, A2
Mazzari, S1
Canella, R1
Petrelli, L1
Marcolongo, G1
Conti, S1
Costa, B1
Colleoni, M1
Parolaro, D1
Giagnoni, G1

Other Studies

12 other studies available for palmidrol and Edema

ArticleYear
Effect of Ultra-Micronized-Palmitoylethanolamide and Acetyl-l-Carnitine on Experimental Model of Inflammatory Pain.
    International journal of molecular sciences, 2021, Feb-17, Volume: 22, Issue:4

    Topics: Acetylcarnitine; Amides; Animals; Carrageenan; Cell Count; Cyclooxygenase 2; Disease Models, Animal;

2021
A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models.
    BMC veterinary research, 2017, Aug-02, Volume: 13, Issue:1

    Topics: Administration, Oral; Amides; Animals; Anti-Inflammatory Agents; Carrageenan; Drug Combinations; Ede

2017
Micronized palmitoylethanolamide reduces joint pain and glial cell activation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2018, Volume: 67, Issue:10

    Topics: Amides; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Edema; Ethanolamin

2018
Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain.
    Journal of neuroinflammation, 2014, Aug-28, Volume: 11

    Topics: Administration, Oral; Amides; Analgesics; Animals; Carrageenan; Chemistry, Pharmaceutical; Chromatog

2014
Nanoparticles prolong N-palmitoylethanolamide anti-inflammatory and analgesic effects in vivo.
    Colloids and surfaces. B, Biointerfaces, 2016, May-01, Volume: 141

    Topics: Adult; Amides; Analgesics; Animals; Anti-Inflammatory Agents; Calorimetry, Differential Scanning; Ca

2016
A new co-micronized composite containing palmitoylethanolamide and polydatin shows superior oral efficacy compared to their association in a rat paw model of carrageenan-induced inflammation.
    European journal of pharmacology, 2016, 07-05, Volume: 782

    Topics: Active Transport, Cell Nucleus; Administration, Oral; Amides; Animals; Carrageenan; Cell Line, Tumor

2016
The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide.
    Molecular pharmacology, 2005, Volume: 67, Issue:1

    Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Carrageenan; Crosses, Genet

2005
The cannabinoid CB2 receptor selective agonist JWH133 reduces mast cell oedema in response to compound 48/80 in vivo but not the release of beta-hexosaminidase from skin slices in vitro.
    Life sciences, 2006, Jan-02, Volume: 78, Issue:6

    Topics: Amides; Animals; beta-N-Acetylhexosaminidases; Cannabinoids; Capillary Permeability; Edema; Endocann

2006
Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan-induced paw edema in mice.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:3

    Topics: Amides; Animals; Carrageenan; Central Nervous System; Drug Administration Routes; Edema; Endocannabi

2007
A saturated N-acylethanolamine other than N-palmitoyl ethanolamine with anti-inflammatory properties: a neglected story...
    Journal of neuroendocrinology, 2008, Volume: 20 Suppl 1

    Topics: Amides; Animals; Anti-Inflammatory Agents; Benzoxazines; Body Temperature; Camphanes; Cannabinoid Re

2008
N-(2-hydroxyethyl)hexadecanamide is orally active in reducing edema formation and inflammatory hyperalgesia by down-modulating mast cell activation.
    European journal of pharmacology, 1996, Apr-11, Volume: 300, Issue:3

    Topics: Amides; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell De

1996
Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: Acute Disease; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Cannabinoid Rece

2002