Page last updated: 2024-11-02

palmidrol and Depressive Disorder, Major

palmidrol has been researched along with Depressive Disorder, Major in 4 studies

palmidrol: a cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection
palmitoyl ethanolamide : An N-(long-chain-acyl)ethanolamine that is the ethanolamide of palmitic (hexadecanoic) acid.

Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to assess the safety, tolerability and efficacy of palmitoylethanolamide (PEA) when dosed at 300 mg and 600 mg per day on symptoms of knee osteoarthritis."2.90A double-blind randomized placebo controlled study assessing safety, tolerability and efficacy of palmitoylethanolamide for symptoms of knee osteoarthritis. ( Steels, E; Venkatesh, R; Vitetta, G; Vitetta, L, 2019)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghazizadeh-Hashemi, M1
Ghajar, A1
Shalbafan, MR1
Ghazizadeh-Hashemi, F1
Afarideh, M1
Malekpour, F1
Ghaleiha, A1
Ardebili, ME1
Akhondzadeh, S1
Steels, E2
Venkatesh, R1
Vitetta, G1
Vitetta, L1
Meyer, JD1
Crombie, KM1
Cook, DB1
Hillard, CJ2
Koltyn, KF1
Hill, MN1
Miller, GE1
Carrier, EJ1
Gorzalka, BB1

Trials

2 trials available for palmidrol and Depressive Disorder, Major

ArticleYear
Palmitoylethanolamide as adjunctive therapy in major depressive disorder: A double-blind, randomized and placebo-controlled trial.
    Journal of affective disorders, 2018, Volume: 232

    Topics: Adult; Amides; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Chemotherapy, Adjuvan

2018
A double-blind randomized placebo controlled study assessing safety, tolerability and efficacy of palmitoylethanolamide for symptoms of knee osteoarthritis.
    Inflammopharmacology, 2019, Volume: 27, Issue:3

    Topics: Adult; Aged; Amides; Anti-Inflammatory Agents, Non-Steroidal; Depressive Disorder, Major; Double-Bli

2019

Other Studies

2 other studies available for palmidrol and Depressive Disorder, Major

ArticleYear
Serum Endocannabinoid and Mood Changes after Exercise in Major Depressive Disorder.
    Medicine and science in sports and exercise, 2019, Volume: 51, Issue:9

    Topics: Adult; Affect; Amides; Arachidonic Acids; Depressive Disorder, Major; Endocannabinoids; Ethanolamine

2019
Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress.
    Psychoneuroendocrinology, 2009, Volume: 34, Issue:8

    Topics: Adult; Amides; Arachidonic Acids; Cannabinoid Receptor Modulators; Case-Control Studies; Depressive

2009