paeonol has been researched along with Inflammation in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.13) | 29.6817 |
| 2010's | 12 (37.50) | 24.3611 |
| 2020's | 19 (59.38) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, EJ; Huang, H; Kang, SS; Kim, HH; Kim, JS; Lee, Y | 1 |
| Dong, FX; Qi, JH; Wang, XL | 1 |
| Chen, G; Guo, T; Yang, L | 1 |
| Kiasalari, Z; Roghani, M; Tayanloo-Beik, A | 1 |
| Khalili, M; Kiasalari, Z; Pourmohammadi, S; Roghani, M | 1 |
| Cao, GM; Diao, LZ; Du, JC; Hu, YS; Liu, X; Liu, XH; Shi, JB; Wu, J; Zhang, ZY; Zhu, R | 1 |
| Bing, X; Chen, K; Gu, Y; Xi, B; Xie, J | 1 |
| Liu, J; Liu, K; Song, J; Sun, T; Wang, J; Wang, S; Wang, T; Xu, W | 1 |
| Chu, C; Li, J; Liu, ML; Meng, Q; Shen, HC; Wang, H; Yu, SJ; Zhang, T | 1 |
| Cheng, J; Ji, K; Li, J; Pan, Q; Yang, C; Zhu, Q | 1 |
| Dai, M; He, H; Huang, H; Liu, Y; Shi, X; Wang, T; Wu, H; Yang, Y | 1 |
| Chen, D; He, M; Huang, H; Li, C; Li, H; Lin, J; Liu, X; Mei, L; Miao, J; Wen, Q; Xu, Q; Ye, P; Ye, S; Zhang, C; Zhao, K; Zhou, J; Zhou, X | 1 |
| Ma, K; Shao, J; Shi, G; Wang, C; Wang, T; Wu, D; Wu, J; Yan, G | 1 |
| Hafez, HM; Mohamed, HH; Mohamed, MZ; Morsy, MA | 1 |
| Cross, AL; Edwards, SW; Hawkes, J; Moots, RJ; Wright, HL | 1 |
| Ge, Y; Ma, K; Pan, M; Shao, J; Wang, C; Wang, T; Wu, D; Yan, G; Zhang, C | 1 |
| Dai, M; Jia, Y; Liu, YR; Shao, Q; Zhang, HH | 1 |
| Du, Y; Guo, Y; Pu, Y; Wang, B; Wang, Z; Xie, L; Yuan, J; Zhang, T | 1 |
| Dai, M; He, H; Huang, H; Liu, Y; Shi, X; Sun, Y; Wu, H; Xie, X | 1 |
| Gao, MR; Li, XB; Qiu, C; Tian, DD; Wang, M; Wang, WJ; Wu, YM; Yang, LD; Yu, W | 1 |
| Chen, X; Lan, J; Li, H; Li, S; Liu, X; Miao, J; Ye, P; Ye, S; You, A; Zhong, J | 1 |
| Feng, Z; Guo, X; Lou, Y; Tang, Q; Wang, C; Wang, J; Yu, X; Zheng, W | 1 |
| Chu, X; Kong, R; Liu, M; Lv, W; Piao, H; Shao, H; Wang, C; Zhao, Y; Zhong, S | 1 |
| Chen, D; Chen, J; Deng, R; Du, S; Huang, H; Lei, H; Li, C; Li, H; Li, Y; Liu, A; Liu, X; Mei, L; Miao, J; Wen, Q; Xu, Q; Zhang, S; Zhou, J | 1 |
| Cheng, C; Feng, ZJ; Jiang, H; Li, J; Liu, CM; Ma, JQ; Sun, JM; Yang, HX; Yang, W | 1 |
| Chen, JJ; Chen, P; Dai, M | 1 |
| Chang, CY; Chang, WJ; Cheng, WC; Chiang, CY; Fu, E; Tu, HP | 1 |
| Chen, DQ; Du, Y; Fan, HY; Liu, T; Qi, D; Yang, MY; Yu, C; Zhang, LM; Zhang, ZK; Zhao, F | 1 |
| Cho, H; Han, IO; Hwang, JS; Jung, EH; Kim, KH; Kwon, MY; Lyoo, IK; Park, JH; Shin, S | 1 |
| Deng, H; He, LX; Huang, F; Li, M; Li, X; Nie, H; Tong, X; Tu, Y; Wu, S; Yang, L; Zeng, J; Zhu, M | 1 |
| Hsu, YY; Lo, YC; Shih, YT; Tseng, YT | 1 |
| Himaya, SW; Kim, SK; Qian, ZJ; Ryu, B | 1 |
1 review(s) available for paeonol and Inflammation
| Article | Year |
|---|---|
Review of the Protective Mechanism of Paeonol on Cardiovascular Disease.
Topics: Acetophenones; Cardiovascular Diseases; Drugs, Chinese Herbal; Humans; Inflammation | 2023 |
31 other study(ies) available for paeonol and Inflammation
| Article | Year |
|---|---|
A genome-wide microarray analysis reveals anti-inflammatory target genes of paeonol in macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Cells, Cultured; Chemokines; Drugs, Chinese Herbal; Gene Expression Profiling; Gene Expression Regulation; Glucosides; Inflammation; Interleukins; Lipopolysaccharides; Macrophages; Mice; Monoterpenes; Oligonucleotide Array Sequence Analysis; Toll-Like Receptors | 2008 |
Exploring targets and signaling pathways of paeonol involved in relieving inflammation based on modern technology.
Topics: Acetophenones; Anti-Inflammatory Agents; Drugs, Chinese Herbal; Humans; Inflammation; Molecular Docking Simulation; Signal Transduction; Technology | 2022 |
Paeonol reduces IL-β production by inhibiting the activation of nucleotide oligomerization domain-like receptor protein-3 inflammasome and nuclear factor-κB in macrophages.
Topics: Acetophenones; Animals; Carrier Proteins; Caspase 1; Inflammasomes; Inflammation; Lipopolysaccharides; Macrophages; NF-kappa B; NF-KappaB Inhibitor alpha; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides; Rats; Uric Acid | 2022 |
Paeonol Ameliorates Cognitive Deficits in Streptozotocin Murine Model of Sporadic Alzheimer's Disease via Attenuation of Oxidative Stress, Inflammation, and Mitochondrial Dysfunction.
Topics: Acetophenones; Acetylcholinesterase; Alzheimer Disease; Animals; Cognition; Cognitive Dysfunction; Disease Models, Animal; Inflammation; Maze Learning; Mice; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Streptozocin | 2022 |
Paeonol Ameliorates Cuprizone-Induced Hippocampal Demyelination and Cognitive Deficits through Inhibition of Oxidative and Inflammatory Events.
Topics: Acetophenones; Animals; Cognition; Cuprizone; Disease Models, Animal; Hippocampus; Inflammation; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Oxidative Stress | 2022 |
Discovery of novel paeonol-based derivatives against skin inflammation
Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Female; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Microsomes, Liver; Mitogen-Activated Protein Kinase Kinases; Molecular Structure; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Skin; Structure-Activity Relationship | 2022 |
Protective effects of paeonol against lipopolysaccharide-induced liver oxidative stress and inflammation in gibel carp (Carassius auratus gibelio).
Topics: Acetophenones; Animals; Antioxidants; Goldfish; Inflammation; Lipopolysaccharides; Liver; Oxidative Stress; Transaminases | 2022 |
Paeonol ameliorates diabetic erectile dysfunction by inhibiting HMGB1/RAGE/NF-kB pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Erectile Dysfunction; Glucose; HMGB1 Protein; Humans; Inflammation; Male; NF-kappa B; Rats; Rats, Sprague-Dawley | 2023 |
Paeonol alleviates placental inflammation and apoptosis in preeclampsia by inhibiting the JAK2/STAT3 signaling pathway.
Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Cytokines; Female; Humans; Inflammation; Interleukin-4; Interleukin-6; Janus Kinase 2; Mice; Placenta; Pre-Eclampsia; Pregnancy; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2022 |
Paeonol reduces microbial metabolite α-hydroxyisobutyric acid to alleviate the ROS/TXNIP/NLRP3 pathway-mediated endothelial inflammation in atherosclerosis mice.
Topics: Animals; Atherosclerosis; Diet, High-Fat; Endothelial Cells; Inflammation; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species | 2023 |
Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; HMGB1 Protein; Humans; Inflammation; Lipopolysaccharides; Mice; MicroRNAs; NF-kappa B; Paeonia; RAW 264.7 Cells; Sepsis | 2019 |
Paeonol ameliorates murine alcohol liver disease via mycobiota-mediated Dectin-1/IL-1β signaling pathway.
Topics: Acetophenones; Alanine Transaminase; Animals; Aspartate Aminotransferases; beta-Glucans; Caspase 1; Cholesterol; Cluster Analysis; Dysbiosis; Inflammation; Interleukin-1beta; Intestinal Mucosa; Kupffer Cells; Lectins, C-Type; Lipogenesis; Liver; Liver Diseases, Alcoholic; Male; Mice, Inbred C57BL; Mycobiome; NLR Family, Pyrin Domain-Containing 3 Protein; Proteoglycans; Signal Transduction; Triglycerides | 2020 |
Paeonol protects against testicular ischaemia-reperfusion injury in rats through inhibition of oxidative stress and inflammation.
Topics: Acetophenones; Animals; Gene Expression; Glutathione; HSP70 Heat-Shock Proteins; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Inflammation; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Rats; Reperfusion Injury; Spermatic Cord Torsion; Superoxide Dismutase; Testis; Testosterone; Tumor Necrosis Factor-alpha | 2020 |
APPA (apocynin and paeonol) modulates pathological aspects of human neutrophil function, without supressing antimicrobial ability, and inhibits TNFα expression and signalling.
Topics: Acetophenones; Anti-Inflammatory Agents; Apoptosis; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Drug Combinations; Humans; Inflammation; Neutrophils; Reactive Oxygen Species; Signal Transduction; Tumor Necrosis Factor-alpha | 2020 |
Paeonol alleviates dextran sodium sulfate induced colitis involving Candida albicans-associated dysbiosis.
Topics: Acetophenones; Animals; Candida albicans; Colitis, Ulcerative; Cytokines; Dextrans; Disease Models, Animal; Dysbiosis; Female; Inflammation; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Plant Extracts; Signal Transduction; Sulfates | 2021 |
[Inhibitory effect of paeonol on aortic endothelial inflammation in atherosclerotic rats by up-regulation of caveolin-1 expression and suppression of NF-κB pathway].
Topics: Acetophenones; Animals; Caveolin 1; Endothelial Cells; Endothelium, Vascular; Inflammation; NF-kappa B; Rats; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation | 2020 |
Effects of Paeonol and Gastroretention Tablets of Paeonol on Experimental Gastric Ulcers and Intestinal Flora in Rats.
Topics: Acetic Acid; Acetophenones; Animals; Antioxidants; Catalase; Gastric Acid; Gastric Mucosa; Gastrointestinal Microbiome; Inflammation; Intestines; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stomach Ulcer; Superoxide Dismutase; Tablets | 2020 |
Paeonol inhibits NLRP3 mediated inflammation in rat endothelial cells by elevating hyperlipidemic rats plasma exosomal miRNA-223.
Topics: Acetophenones; Animals; Cell Survival; Cytokines; Diet, High-Fat; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Exosomes; Hyperlipidemias; Inflammasomes; Inflammation; Inflammation Mediators; Male; MicroRNAs; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley | 2020 |
Paeonol ameliorates CFA-induced inflammatory pain by inhibiting HMGB1/TLR4/NF-κB p65 pathway.
Topics: Acetophenones; Animals; HMGB1 Protein; Hyperalgesia; Inflammation; Male; Mice; NF-kappa B; Pain Threshold; Signal Transduction; Toll-Like Receptor 4 | 2021 |
Paeonol attenuates inflammation by confining HMGB1 to the nucleus.
Topics: Acetophenones; Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Cell Nucleus; Disease Models, Animal; Gene Expression Profiling; HMGB1 Protein; Inflammation; Male; Mice; Mice, Knockout; Models, Molecular; NF-kappa B; Protein Transport; RAW 264.7 Cells; Signal Transduction; Structure-Activity Relationship | 2021 |
Paeonol Inhibits IL-1β-Induced Inflammation via PI3K/Akt/NF-κB Pathways: In Vivo and Vitro Studies.
Topics: Acetophenones; Animals; Cartilage; Cells, Cultured; Chondrocytes; Humans; Inflammation; Interleukin-1beta; Mice; NF-kappa B; Osteoarthritis; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2017 |
Paeonol alleviates interleukin-1β-induced inflammatory responses in chondrocytes during osteoarthritis.
Topics: Acetophenones; Animals; Apoptosis; Cartilage; Cell Proliferation; Cell Survival; Chondrocytes; Extracellular Matrix; Inflammation; Injections, Intra-Articular; Interleukin-1beta; Male; Menisci, Tibial; Osteoarthritis; Rats, Sprague-Dawley; Reactive Oxygen Species | 2017 |
Paeonol Reduces the Nucleocytoplasmic Transportation of HMGB1 by Upregulating HDAC3 in LPS-Induced RAW264.7 Cells.
Topics: Acetophenones; Active Transport, Cell Nucleus; Animals; Histone Acetyltransferases; Histone Deacetylases; HMGB1 Protein; Inflammation; Lipopolysaccharides; Mice; p300-CBP Transcription Factors; RAW 264.7 Cells; Up-Regulation | 2018 |
Role of AMPK pathway in lead-induced endoplasmic reticulum stress in kidney and in paeonol-induced protection in mice.
Topics: Acetophenones; Adenylate Kinase; Animals; Cells, Cultured; Drugs, Chinese Herbal; eIF-2 Kinase; Endoplasmic Reticulum Stress; Enzyme Activation; Glomerular Mesangium; Glycogen Synthase Kinase 3 beta; Inflammation; Inflammation Mediators; Interleukin-6; Lead; Male; MAP Kinase Kinase 4; Membrane Proteins; Mice, Inbred ICR; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Paeonia; Protein Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2018 |
[Effect of paeonol on LPS-induced rat vascular endothelial cell adhesion reaction].
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Atherosclerosis; Cell Adhesion; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Inflammation; Lipopolysaccharides; Male; Monocytes; Paeonia; Protective Agents; Rats; Rats, Sprague-Dawley | 2013 |
Effect of paeonol on tissue destruction in experimental periodontitis of rats.
Topics: Acetophenones; Alveolar Bone Loss; Animals; Cytokines; Disease Models, Animal; Gingiva; Inflammation; Inflammation Mediators; Ligation; Lipopolysaccharides; Osteoclasts; Periodontitis; Phytotherapy; Rats; Rats, Sprague-Dawley; Tooth Socket | 2014 |
Paeonol protects endotoxin-induced acute kidney injury: potential mechanism of inhibiting TLR4-NF-κB signal pathway.
Topics: Acetophenones; Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cell Survival; Cytokines; Dendritic Cells; Endotoxins; Enzyme-Linked Immunosorbent Assay; Inflammation; Kidney; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Phosphorylation; Signal Transduction; Toll-Like Receptor 4; Transcription Factor RelA | 2016 |
A tryptamine-paeonol hybridization compound inhibits LPS-mediated inflammation in BV2 cells.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Cell Line; Cyclooxygenase 2; Cytokines; Inflammation; Inflammation Mediators; Lipopolysaccharides; Microglia; NF-kappa B; Nitric Oxide; Signal Transduction; Tryptamines | 2016 |
Paeonol Suppresses Neuroinflammatory Responses in LPS-Activated Microglia Cells.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Cell Line; Dose-Response Relationship, Drug; Inflammation; Lipopolysaccharides; Mice; Microglia; Neuroimmunomodulation; Signal Transduction; Toll-Like Receptor 4 | 2016 |
Paeonol attenuates microglia-mediated inflammation and oxidative stress-induced neurotoxicity in rat primary microglia and cortical neurons.
Topics: Acetophenones; Animals; Animals, Newborn; Anti-Inflammatory Agents; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Female; Heme Oxygenase-1; Inflammation; Inflammation Mediators; Lipopolysaccharides; Microglia; Mitogen-Activated Protein Kinases; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type II; Oxidative Stress; Oxidopamine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 2012 |
Paeonol from Hippocampus kuda Bleeler suppressed the neuro-inflammatory responses in vitro via NF-κB and MAPK signaling pathways.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Cell Line; Cytokines; Dinoprostone; Humans; Inflammation; Lipopolysaccharides; Mice; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Signal Transduction; Smegmamorpha | 2012 |