Page last updated: 2024-08-23

paclitaxel and Osteosarcoma

paclitaxel has been researched along with Osteosarcoma in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (10.77)	18.2507
2000's	23 (35.38)	29.6817
2010's	28 (43.08)	24.3611
2020's	7 (10.77)	2.80

Authors

Authors	Studies
Aschero, R; Burgueño, V; Carcaboso, AM; Castillo-Ecija, H; de Álava, E; Gómez-Caballero, A; Gomez-Gonzalez, S; Ibarra, M; Mora, J; Muñoz-Aznar, O; Pascual-Pasto, G; Resa-Pares, C; Schaiquevich, P; Sosnik, A; Suñol, M; Tirado, OM; Unceta, N; Vila-Ubach, M	1
Cai, JX; Li, YJ; Liu, JH; Qiu, XH; Wu, JY; Xiang, DX; Xu, P; Xu, WJ	1
Ahangar, NK; Alizadeh, N; Baghbanzadeh, A; Baradaran, B; Dolatkhah, K; Khalaj-Kondori, M; Mokhtarzadeh, A; Shadbad, MA	1
Hou, H; Li, Y; Zhang, P; Zhang, Z	1
Gao, J; Lian, M; Liu, Y; Qian, J; Qiao, Z; Su, Y; Sun, B; Wu, F; Zhu, B; Zhu, X	1
Fan, B; Feng, Z; Lu, B; Shi, Y	1
Elboray, EE; Endo, K; Kajikuri, J; Kito, H; Ohya, S; Suzuki, T	1
Duan, R; Li, C; Wang, F; Yangi, JC	1
Akabani, G; Butters, AS; Clanton, R; Fan, J; Hernandez, S; Khan, S; Li, R; Lin, YN; MacLoughlin, R; Smolen, J; Song, Y; Su, L; Wang, H; Wooley, KL; Zhang, F	1
Ballestri, M; Columbaro, M; Donati, DM; Duchi, S; Ferroni, C; Guerrini, A; Lucarelli, E; Martella, E; Santi, S; Serra, M; Sotgiu, G; Varchi, G	1
Chang, YJ; Chen, HA; Huang, CY; Huang, MT; Makondi, PT; Wang, JW; Wei, PL	1
Bi, D; Guo, Y; Han, M; Qi, X; Wang, X; Yue, F; Zhao, L	1
Chen, Z; Guan, M; Zhao, W	1
Caraglia, M; Chiosi, E; Di Maiolo, F; Esposito, A; Naviglio, S; Sapio, L; Sorvillo, L; Spina, A	1
Feng, D; Gong, W; Huang, T; Jiang, G; Li, X; Zou, C	1
Kim, HJ; Kim, JM; Kim, YJ; Lee, KY; Lee, SG; Park, JE; Yoo, YH	1
Guo, C; Han, Y; Li, Y; Meng, X; Shen, Z; Wan, L; Yang, Q; Yu, Q; Zhou, Z	1
Baruchel, S; Elias, E; Kumar, S; Leadley, M; Marrano, P; Thorner, P; Zhang, L	1
Huang, CY; Su, HL; Tang, CH; Tsai, HC	1
Cripe, TP; Currier, M; Eaves, D; Wagner, LM; Yin, H	1
Choy, E; Cote, G; Duan, Z; Harmon, D; Hornicek, FJ; Mankin, H; Osaka, E; Shen, J; Yang, P; Yang, X; Zhang, Z	1
Choy, E; Cote, G; Duan, Z; Gray, NS; Harmon, D; Hornicek, FJ; Hua, Y; Mankin, H; Shen, J; Ye, S; Zhang, J; Zhang, Y	1
Elsabahy, M; Fan, J; Gonzalez, AM; Gustafson, TP; Hughes, DM; Johnson, R; Leininger, SE; Lenox, MW; Li, R; Nelson, LD; Pavía-Sanders, A; Pollack, SF; Raymond, JE; Wooley, KL; Zhang, F; Zhang, S; Zou, J	1
Wang, B; Xu, M; Xu, SF; Yu, XC	1
Cai, J; Li, J; Li, Z; Wang, F; Zhao, K; Zou, L	1
Chen, T; Guo, Y; Huang, C; Huang, Z; Li, G; Li, J	1
Choy, E; Cote, G; Duan, Z; Gao, Y; Gray, NS; Harmon, D; Hornicek, FJ; Li, Y; Mankin, H; Shen, J; Ye, S; Zhang, J	1
Chen, TH; Chen, WM; Chou, YS; Ke, WT; Lin, YC; Liu, CL; Liu, CY; Wang, JY; Wen, YS; Yang, MH; Yen, CC	1
Liu, M; Wang, Y; Xiao, X; Xiusheng, H	1
Li, F; Lu, Y; Sun, J; Xu, T	1
Duan, Z; Hornicek, FJ; Mankin, H; Schwab, JH; Wood, KB; Yang, C	1
Babo, I; Harisi, R; Jeney, A; Kenessey, I; Olah, JN; Paku, S; Pogany, G; Timar, F	1
Lin, L; Liu, SY; Liu, X; Song, SX	1
Jansen, JA; Kamphuis, GJ; Lopez-Heredia, MA; Öner, FC; Thüne, PC; Walboomers, XF	1
Ding, Y; Hao, L; Niu, X; Xu, H; Yang, Y; Zhang, Q	1
Feng, DP; Gong, WH; Huang, T; Jiang, GJ; Li, XC; Li, XH; Zou, CP	2
Bar-Eli, M; Doucet, M; Fidler, IJ; Lev, DC; Lewis, V; McGary, EC; Mills, L; Weber, K	1
Au, JL; Gan, Y; Johnston, J; Mo, Y; Song, S; Wientjes, MG; Xiao, X	1
Dong, F; Guo, W; Lei, W; Zeng, C	1
Jordan, MA; Kelling, J; Sullivan, K; Wilson, L	1
Braunschweiger, P; De Young, LR; Hamilton, K; Lampidis, TJ; Maschek, G; Priebe, W; Savaraj, N; Tidmarsh, GF	1
Agner, J; Bartek, J; Falck, J; Lukas, J	1
Li, FB; Liao, WM; Liu, ZC; Zhou, JM; Zhu, JJ; Zhu, XF	1
Boucher, Y; Garkavtsev, I	1
Díaz-Montero, CM; McIntyre, BW	1
Chou, MC; Chung, JG; Lu, KH; Lue, KH	1
Billups, CA; Cheshire, PJ; Creech, J; Favours, E; Houghton, PJ; Lee, FY; Peterson, JK; Smykla, R; Tucker, C	1
Banerjee, D; Bertino, JR; Hu, Z; Li, WW; Magro, PG; Mandola, J; Peters, R; Russo, AJ	1
Guo, W; Tang, S; Tang, XD; Yang, Y	1
Gonos, ES; Lourda, M; Trougakos, IP	1
Benjamin, R; Linke, KA; Moseley, SH; Papadopoulos, NE; Patel, SR; Plager, C; Spirindonidis, CH	1
Magnusson, MK; Mosher, DF; Zhang, Q	1
French, KJ; Magnusson, MK; Mosher, DF; Peyruchaud, O; Zhang, Q	1
Hansson, V; Jahnsen, T; Keryer, G; Landmark, BF; Skålhegg, BS; Taskén, K	1
Banerjee, D; Bertino, JR; Fan, J; Li, W	1
Bellincampi, L; Giordano, A; Masciullo, V; Melino, G; Pucci, B; Tafani, M	1
Karbowski, M; Nishizawa, Y; Spodnik, JH; Teranishi, M; Usukura, J; Wakabayashi, T; Wozniak, M	1
Bos, GD; Burns, BS; Edin, ML; Lester, GE; Tuttle, HG; Wall, ME; Wani, MC	1
Blackburn, A; Buchanan, A; Cunningham, C; Edelman, G; Kirn, D; Maples, P; Nemunaitis, J; Netto, G; Olson, S; Randlev, B; Tong, A	1
Peng, L; Wang, Q; Wang, Z	1
Ara, KY; Arai, K; Maruo, K; Matsuda, H; Uehara, K	1
Hisada, T; Ito, T; Masuda, S; Mochida, A; Morinari, H; Nakahara, K; Nishi, K; Saito, K; Sasaki, S; Tahara, M; Yakumaru, K	1
Duan, Z; Kronish, KM; Lamendola, DE; Penson, RT; Seiden, MV	1
Bissery, MC; Guénard, D; Guéritte-Voegelein, F; Lavelle, F	1

Trials

2 trial(s) available for paclitaxel and Osteosarcoma

Article	Year
Phase II study of paclitaxel in patients with previously treated osteosarcoma and its variants. Cancer, 1996, Aug-15, Volume: 78, Issue:4 Topics: Adult; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Chondrosarcoma; Female; Histiocytoma, Benign Fibrous; Humans; Male; Middle Aged; Osteosarcoma; Paclitaxel	1996
Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity. Gene therapy, 2001, Volume: 8, Issue:10 Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoviridae; Adrenal Gland Neoplasms; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Carcinoma, Papillary; Carcinoma, Squamous Cell; Colonic Neoplasms; Feasibility Studies; Female; Genetic Therapy; Genetic Vectors; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Osteosarcoma; Paclitaxel; Thyroid Neoplasms	2001

Article

Year

Phase II study of paclitaxel in patients with previously treated osteosarcoma and its variants.

Cancer, 1996, Aug-15, Volume: 78, Issue:4

Topics: Adult; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Chondrosarcoma; Female; Histiocytoma, Benign Fibrous; Humans; Male; Middle Aged; Osteosarcoma; Paclitaxel

1996

Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity.

Gene therapy, 2001, Volume: 8, Issue:10

Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoviridae; Adrenal Gland Neoplasms; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Carcinoma, Papillary; Carcinoma, Squamous Cell; Colonic Neoplasms; Feasibility Studies; Female; Genetic Therapy; Genetic Vectors; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Osteosarcoma; Paclitaxel; Thyroid Neoplasms

2001

Other Studies

63 other study(ies) available for paclitaxel and Osteosarcoma

Article	Year
SPARC-mediated long-term retention of nab-paclitaxel in pediatric sarcomas. Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 342 Topics: Albumins; Animals; Bone Neoplasms; Humans; Mice; Osteonectin; Osteosarcoma; Paclitaxel	2022
Hybrid Cell Membrane-Functionalized Biomimetic Nanoparticles for Targeted Therapy of Osteosarcoma. International journal of nanomedicine, 2022, Volume: 17 Topics: Animals; Biomimetics; Bone Neoplasms; Cell Line, Tumor; Cell Membrane; Drug Carriers; Humans; Lactic Acid; Mice; Nanoparticles; Osteosarcoma; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution	2022
Silencing tumor-intrinsic HHLA2 potentiates the anti-tumoral effect of paclitaxel on MG63 cells: Another side of immune checkpoint. Gene, 2023, Mar-01, Volume: 855 Topics: Apoptosis; bcl-2-Associated X Protein; Bone Neoplasms; Caspase 3; Cell Line, Tumor; Humans; Immunoglobulins; Osteosarcoma; Paclitaxel; RNA, Small Interfering	2023
Co-delivery of doxorubicin and paclitaxel by reduction/pH dual responsive nanocarriers for osteosarcoma therapy. Drug delivery, 2020, Volume: 27, Issue:1 Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Mice; Microscopy, Confocal; Nanoparticles; Osteosarcoma; Paclitaxel; Polyethylene Glycols; Polymers; Thioctic Acid; Tissue Distribution	2020
Hydroxyapatite-Bovine Serum Albumin-Paclitaxel Nanoparticles for Locoregional Treatment of Osteosarcoma. Advanced healthcare materials, 2021, Volume: 10, Issue:2 Topics: Adolescent; Cell Line, Tumor; Child; Drug Carriers; Durapatite; Humans; Nanoparticles; Osteogenesis; Osteosarcoma; Paclitaxel; Serum Albumin, Bovine	2021
Blocking miR-27a-3p sensitises Taxol resistant osteosarcoma cells through targeting Fbxw7. Bulletin du cancer, 2021, Volume: 108, Issue:6 Topics: Adolescent; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Child; Drug Resistance, Neoplasm; F-Box-WD Repeat-Containing Protein 7; Female; Humans; Male; MicroRNAs; Molecular Targeted Therapy; Osteosarcoma; Paclitaxel; Up-Regulation	2021
Ca Cancer science, 2021, Volume: 112, Issue:9 Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; F-Box-WD Repeat-Containing Protein 7; Humans; Indoles; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Osteosarcoma; Paclitaxel; Potassium Channel Blockers; RNA, Small Interfering; Spheroids, Cellular; Transfection; Tumor Microenvironment; Up-Regulation	2021
Polymer-lipid hybrid nanoparticles-based paclitaxel and etoposide combinations for the synergistic anticancer efficacy in osteosarcoma. Colloids and surfaces. B, Biointerfaces, 2017, Nov-01, Volume: 159 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Etoposide; Humans; Nanoparticles; Osteosarcoma; Paclitaxel; Polymers	2017
Chemical Design of Both a Glutathione-Sensitive Dimeric Drug Guest and a Glucose-Derived Nanocarrier Host to Achieve Enhanced Osteosarcoma Lung Metastatic Anticancer Selectivity. Journal of the American Chemical Society, 2018, 01-31, Volume: 140, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Dimerization; Dithiothreitol; Drug Carriers; Drug Design; Glucose; Glutathione; Humans; Lung Neoplasms; Molecular Conformation; Nanoparticles; Osteosarcoma; Paclitaxel	2018
Functionalized Keratin as Nanotechnology-Based Drug Delivery System for the Pharmacological Treatment of Osteosarcoma. International journal of molecular sciences, 2018, Nov-20, Volume: 19, Issue:11 Topics: Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Drug Resistance, Neoplasm; Humans; Keratins; Nanoparticles; Nanotechnology; Osteosarcoma; Paclitaxel	2018
Glucose-Regulated Protein 94 Modulates the Response of Osteosarcoma to Chemotherapy. Disease markers, 2019, Volume: 2019 Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; Epirubicin; Gemcitabine; Humans; Membrane Glycoproteins; Osteosarcoma; Paclitaxel	2019
Polydopamine-based surface modification of paclitaxel nanoparticles for osteosarcoma targeted therapy. Nanotechnology, 2019, Jun-21, Volume: 30, Issue:25 Topics: Albumins; Alendronate; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Female; Indoles; Mice; Mice, Inbred BALB C; Nanoparticles; Osteosarcoma; Paclitaxel; Polymers; Surface Properties; Tissue Distribution	2019
Polydatin enhances the chemosensitivity of osteosarcoma cells to paclitaxel. Journal of cellular biochemistry, 2019, Volume: 120, Issue:10 Topics: Apoptosis; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Neoplasm Proteins; Osteosarcoma; Paclitaxel; Stilbenes	2019
Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells. Oncology reports, 2013, Volume: 29, Issue:5 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Synergism; Fluorouracil; Humans; Osteosarcoma; Paclitaxel; Phosphates	2013
Enhancement of osteosarcoma cell sensitivity to cisplatin using paclitaxel in the presence of hyperthermia. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2013, Volume: 29, Issue:3 Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Survival; Cisplatin; fas Receptor; Humans; Hyperthermia, Induced; Osteosarcoma; Paclitaxel	2013
Cytoprotective role of autophagy during paclitaxel-induced apoptosis in Saos-2 osteosarcoma cells. International journal of oncology, 2013, Volume: 42, Issue:6 Topics: Adenine; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Bone Neoplasms; Caspase 3; Cell Death; Cell Line, Tumor; Cytochromes c; Cytoprotection; Humans; Membrane Potential, Mitochondrial; Mitochondria; Osteosarcoma; Paclitaxel; X-Linked Inhibitor of Apoptosis Protein	2013
ABCB1-overexpressing MG63/DOX cell xenograft model: maintain the MDR phenotype in vivo. Pharmaceutical biology, 2013, Volume: 51, Issue:8 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Cell Line, Tumor; Cytarabine; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Osteosarcoma; Paclitaxel; Verapamil; Xenograft Model Antitumor Assays	2013
Nab-paclitaxel is an active drug in preclinical model of pediatric solid tumors. Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Nov-01, Volume: 19, Issue:21 Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Female; Humans; Mice; Neoplasms; Neuroblastoma; Osteosarcoma; Paclitaxel; Rhabdomyosarcoma; Xenograft Model Antitumor Assays	2013
CTGF increases drug resistance to paclitaxel by upregulating survivin expression in human osteosarcoma cells. Biochimica et biophysica acta, 2014, Volume: 1843, Issue:5 Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Connective Tissue Growth Factor; Drug Resistance, Neoplasm; Humans; In Situ Nick-End Labeling; Inhibitor of Apoptosis Proteins; Mice; Mice, Nude; Osteosarcoma; Paclitaxel; Real-Time Polymerase Chain Reaction; Survivin; Up-Regulation	2014
Preclinical evaluation of nanoparticle albumin-bound paclitaxel for treatment of pediatric bone sarcoma. Pediatric blood & cancer, 2014, Volume: 61, Issue:11 Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Bone Neoplasms; Cell Line, Tumor; Child; Drug Evaluation, Preclinical; Female; Humans; Mice; Nanoparticles; Osteonectin; Osteosarcoma; Paclitaxel; Sarcoma, Ewing	2014
Prevention of multidrug resistance (MDR) in osteosarcoma by NSC23925. British journal of cancer, 2014, Jun-10, Volume: 110, Issue:12 Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Osteosarcoma; Paclitaxel; Piperidines; Quinolines	2014
A-770041 reverses paclitaxel and doxorubicin resistance in osteosarcoma cells. BMC cancer, 2014, Sep-19, Volume: 14 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Osteosarcoma; Paclitaxel; Peptide Library; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; src-Family Kinases	2014
Improving paclitaxel delivery: in vitro and in vivo characterization of PEGylated polyphosphoester-based nanocarriers. Journal of the American Chemical Society, 2015, Feb-11, Volume: 137, Issue:5 Topics: Alkynes; Animals; Azides; Bone Neoplasms; Catalysis; Cell Line, Tumor; Copper; Drug Carriers; Drug Liberation; Esters; Half-Life; Humans; Hydrophobic and Hydrophilic Interactions; Lung Neoplasms; Mice; Micelles; Models, Molecular; Molecular Conformation; Nanoparticles; Osteosarcoma; Paclitaxel; Polyethylene Glycols; Polymers; Tissue Distribution	2015
Paclitaxel and etoposide co-loaded polymeric nanoparticles for the effective combination therapy against human osteosarcoma. Journal of nanobiotechnology, 2015, Mar-21, Volume: 13 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Drug Carriers; Etoposide; Humans; Lactic Acid; Nanoparticles; Osteosarcoma; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer	2015
X609, a novel manassantin A derivative, exhibits antitumor activity in MG-63 human osteosarcoma cells in vitro and in vivo. Molecular medicine reports, 2015, Volume: 12, Issue:2 Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Caspases; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lignans; Mice; Mice, Nude; Mitochondria; Osteosarcoma; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays	2015
Paxilitaxel induces apoptosis accompanied by protective autophagy in osteosarcoma cells through hypoxia-inducible factor-1α pathway. Molecular medicine reports, 2015, Volume: 12, Issue:3 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Bone and Bones; Bone Neoplasms; Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mitochondria; Osteosarcoma; Paclitaxel; Signal Transduction	2015
NVP-TAE684 reverses multidrug resistance (MDR) in human osteosarcoma by inhibiting P-glycoprotein (PGP1) function. British journal of pharmacology, 2016, Volume: 173, Issue:3 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Osteosarcoma; Paclitaxel; Protein Kinase Inhibitors; Pyrimidines	2016
Cytotoxic mechanism of PLK1 inhibitor GSK461364 against osteosarcoma: Mitotic arrest, apoptosis, cellular senescence, and synergistic effect with paclitaxel. International journal of oncology, 2016, Volume: 48, Issue:3 Topics: Adenosine Triphosphate; Apoptosis; Benzimidazoles; beta-Galactosidase; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; Computational Biology; Drug Synergism; Enzyme Inhibitors; Flow Cytometry; Humans; Mitosis; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteosarcoma; Paclitaxel; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Thiophenes	2016
Overexpression of miR-422a inhibits cell proliferation and invasion, and enhances chemosensitivity in osteosarcoma cells. Oncology reports, 2016, Volume: 36, Issue:6 Topics: 3' Untranslated Regions; Antineoplastic Agents; Base Sequence; Binding Sites; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasm Invasiveness; Osteosarcoma; Paclitaxel; RNA Interference; Transforming Growth Factor beta2	2016
Tetrandrine prevents multidrug resistance in the osteosarcoma cell line, U-2OS, by preventing Pgp overexpression through the inhibition of NF-κB signaling. International journal of molecular medicine, 2017, Volume: 39, Issue:4 Topics: ATP Binding Cassette Transporter, Subfamily B; Benzylisoquinolines; Bone Neoplasms; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; NF-kappa B; Osteosarcoma; Paclitaxel; Signal Transduction	2017
RAIDD expression is impaired in multidrug resistant osteosarcoma cell lines. Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:3 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line, Tumor; CRADD Signaling Adaptor Protein; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Oligonucleotide Array Sequence Analysis; Osteosarcoma; Paclitaxel; Phenotype; Poly(ADP-ribose) Polymerases; Time Factors; Transfection	2009
Differential inhibition of single and cluster type tumor cell migration. Anticancer research, 2009, Volume: 29, Issue:8 Topics: Adolescent; Bone Neoplasms; Cell Culture Techniques; Cell Movement; Cell Proliferation; Chromones; Deoxyuridine; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibrosarcoma; Flavonoids; Humans; Imidazoles; Male; Morpholines; Okadaic Acid; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Signal Transduction; Tumor Cells, Cultured	2009
Molecular mechanism of cell apoptosis by paclitaxel and pirarubicin in a human osteosarcoma cell line. Chemotherapy, 2010, Volume: 56, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Drug; Doxorubicin; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Osteosarcoma; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Time Factors	2010
An injectable calcium phosphate cement for the local delivery of paclitaxel to bone. Biomaterials, 2011, Volume: 32, Issue:23 Topics: Biological Availability; Bone Cements; Bone Neoplasms; Breast Neoplasms; Calcium Phosphates; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Delivery Systems; Durapatite; Female; Humans; Microscopy, Electron, Scanning; Osteosarcoma; Paclitaxel; Photoelectron Spectroscopy; Porosity; Serum Albumin	2011
The efficacy of abraxane on osteosarcoma xenografts in nude mice and expression of secreted protein, acidic and rich in cysteine. The American journal of the medical sciences, 2012, Volume: 344, Issue:3 Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Female; Humans; Maximum Tolerated Dose; Mice; Mice, Nude; Osteonectin; Osteosarcoma; Paclitaxel; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma, Experimental; Tumor Burden; Xenograft Model Antitumor Assays	2012
Induction of apoptosis by a combination of paclitaxel and carboplatin in the presence of hyperthermia. Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Carboplatin; Combined Modality Therapy; fas Receptor; Fever; Humans; Immunoenzyme Techniques; Osteosarcoma; Paclitaxel; Tumor Cells, Cultured	2012
Synergistic increase in the sensitivity of osteosarcoma cells to thermochemotherapy with combination of paclitaxel and etoposide. Molecular medicine reports, 2012, Volume: 6, Issue:5 Topics: Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Drug Therapy, Combination; Etoposide; fas Receptor; Humans; Osteosarcoma; Paclitaxel; Temperature	2012
Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571. Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:11 Topics: Animals; Antineoplastic Agents; Benzamides; Blotting, Western; Bone Neoplasms; Cell Division; Cell Line, Transformed; Enzyme Inhibitors; Female; Humans; Imatinib Mesylate; In Situ Nick-End Labeling; Mice; Neoplasm Transplantation; Osteosarcoma; Paclitaxel; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tibia; Time Factors; Tumor Cells, Cultured	2002
Simultaneous targeting of telomeres and telomerase as a cancer therapeutic approach. Cancer research, 2003, Feb-01, Volume: 63, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Synergism; Humans; In Situ Hybridization, Fluorescence; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Osteosarcoma; Paclitaxel; Pharyngeal Neoplasms; RNA, Antisense; Telomerase; Telomere; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zidovudine	2003
Paclitaxel-induced apoptosis in osteosarcoma cell line U-2 OS. Chinese medical journal, 2002, Volume: 115, Issue:12 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Micronuclei, Chromosome-Defective; Microscopy, Electron; Osteosarcoma; Paclitaxel; Tumor Cells, Cultured	2002
Suppression of centromere dynamics by Taxol in living osteosarcoma cells. Cancer research, 2003, Jun-01, Volume: 63, Issue:11 Topics: Antineoplastic Agents, Phytogenic; Autoantigens; Bone Neoplasms; Cell Division; Centromere; Centromere Protein B; Chromosomal Proteins, Non-Histone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Humans; Luminescent Proteins; Microtubules; Mitosis; Osteosarcoma; Paclitaxel; Recombinant Fusion Proteins; Spindle Apparatus; Tumor Cells, Cultured	2003
2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo. Cancer research, 2004, Jan-01, Volume: 64, Issue:1 Topics: Animals; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Deoxyglucose; Doxorubicin; Drug Synergism; Humans; Lung Neoplasms; Mice; Mice, Nude; Osteosarcoma; Paclitaxel; Transplantation, Heterologous; Tumor Cells, Cultured	2004
Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathway. Experimental cell research, 2005, Jan-15, Volume: 302, Issue:2 Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Camptothecin; cdc25 Phosphatases; Cell Cycle; Cell Line, Transformed; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; Cisplatin; Cyclin E; DNA; DNA Damage; Doxorubicin; Enzyme Activation; Etoposide; Flow Cytometry; Humans; Kinetics; Osteosarcoma; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; Radiation, Ionizing; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Ultraviolet Rays	2005
The tumor suppressor p33ING1b enhances taxol-induced apoptosis by p53-dependent pathway in human osteosarcoma U2OS cells. Cancer biology & therapy, 2005, Volume: 4, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Cycle Proteins; DNA Repair; DNA-Binding Proteins; Genes, p53; Genes, Tumor Suppressor; Growth Inhibitors; Humans; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Nuclear Proteins; Osteosarcoma; Paclitaxel; Tumor Cells, Cultured; Tumor Suppressor Proteins	2005
An intact ING1-P53 pathway can potentiate the cytotoxic effects of taxol. Cancer biology & therapy, 2005, Volume: 4, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Cell Cycle Proteins; DNA-Binding Proteins; Genes, p53; Genes, Tumor Suppressor; Humans; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; NF-kappa B; Nuclear Proteins; Osteosarcoma; Paclitaxel; Tumor Cells, Cultured; Tumor Suppressor Proteins	2005
Acquisition of anoikis resistance in human osteosarcoma cells does not alter sensitivity to chemotherapeutic agents. BMC cancer, 2005, Apr-13, Volume: 5 Topics: Anoikis; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Separation; Cell Survival; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Extracellular Matrix; Flow Cytometry; Humans; Hypoxia; Neoplasm Metastasis; Osteosarcoma; Paclitaxel; Propidium; Vinblastine	2005
Paclitaxel induces apoptosis via caspase-3 activation in human osteogenic sarcoma cells (U-2 OS). Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2005, Volume: 23, Issue:5 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Caspase 3; Caspase Inhibitors; Caspases; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Osteosarcoma; Paclitaxel	2005
In vivo evaluation of ixabepilone (BMS247550), a novel epothilone B derivative, against pediatric cancer models. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 1 Topics: Animals; Area Under Curve; Brain Neoplasms; Cell Line, Tumor; Clinical Trials as Topic; Disease Models, Animal; Dose-Response Relationship, Drug; Epothilones; Female; Humans; Maximum Tolerated Dose; Mice; Mice, SCID; Microtubules; Mitosis; Models, Chemical; Neoplasm Transplantation; Neuroblastoma; Osteosarcoma; Paclitaxel; Rhabdomyosarcoma; Time Factors; Treatment Outcome; Vinca Alkaloids; Wilms Tumor	2005
E2F-1 overexpression in U2OS cells increases cyclin B1 levels and cdc2 kinase activity and sensitizes cells to antimitotic agents. Cancer research, 2006, Jul-15, Volume: 66, Issue:14 Topics: Bone Neoplasms; CDC2 Protein Kinase; Cell Growth Processes; Cell Line, Tumor; Cyclin B; Cyclin B1; E2F1 Transcription Factor; Humans; Osteosarcoma; Paclitaxel; RNA Interference; RNA, Messenger; Transfection; Vinblastine	2006
[Preliminary report of combination chemotherapy including Arsenic trioxide for stage III osteosarcoma and Ewing sarcoma]. Zhonghua wai ke za zhi [Chinese journal of surgery], 2006, Jun-15, Volume: 44, Issue:12 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Neoplasms; Child; Etoposide; Female; Follow-Up Studies; Humans; Male; Osteosarcoma; Oxides; Paclitaxel; Sarcoma, Ewing; Treatment Outcome	2006
Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of Clusterin/Apolipoprotein J. International journal of cancer, 2007, Feb-01, Volume: 120, Issue:3 Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Clusterin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Osteosarcoma; Paclitaxel; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Time Factors; Up-Regulation	2007
Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction. Molecular biology of the cell, 1997, Volume: 8, Issue:8 Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cattle; Cytoskeleton; Endothelium; Fibronectins; Humans; Lysophospholipids; Microfilament Proteins; Microtubules; Nocodazole; Osteosarcoma; Paclitaxel; Tumor Cells, Cultured; Vinblastine	1997
Sphingosine 1-phosphate stimulates fibronectin matrix assembly through a Rho-dependent signal pathway. Blood, 1999, May-01, Volume: 93, Issue:9 Topics: Binding Sites; Cell Division; Cells, Cultured; Cytoskeleton; Extracellular Matrix; Fibroblasts; Fibronectins; GTP-Binding Proteins; Humans; Lysophospholipase; Lysophospholipids; Male; Nuclear Proteins; Osteosarcoma; Paclitaxel; Peptide Fragments; Pertussis Toxin; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Signal Transduction; Skin; Sphingosine; Transcription Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella; Zinc Fingers	1999
Differential localization of protein kinase A type II isozymes in the Golgi-centrosomal area. Experimental cell research, 1999, May-25, Volume: 249, Issue:1 Topics: Antibodies, Monoclonal; Bone Neoplasms; Cell Line, Transformed; Cells, Cultured; Centrosome; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Female; Fibroblasts; Golgi Apparatus; Granulosa Cells; Humans; Isoenzymes; Keratinocytes; Lymphocytes; Macrophages; Microscopy, Confocal; Microscopy, Fluorescence; Microtubules; Neoplasm Proteins; Nocodazole; Osteosarcoma; Paclitaxel; Second Messenger Systems; Subcellular Fractions; Trophoblasts; Tumor Cells, Cultured	1999
Overexpression of p21(waf1) decreases G2-M arrest and apoptosis induced by paclitaxel in human sarcoma cells lacking both p53 and functional Rb protein. Molecular pharmacology, 1999, Volume: 55, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; CDC2 Protein Kinase; Cell Cycle; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Drug Resistance, Neoplasm; G2 Phase; Humans; Mitosis; Osteosarcoma; Paclitaxel; Retinoblastoma Protein; Tumor Cells, Cultured; Tumor Suppressor Protein p53	1999
Paclitaxel induces apoptosis in Saos-2 cells with CD95L upregulation and Bcl-2 phosphorylation. Experimental cell research, 1999, Oct-10, Volume: 252, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Cell Cycle; Cell Division; Fas Ligand Protein; fas Receptor; Humans; Membrane Glycoproteins; Microscopy, Electron; Osteoblasts; Osteosarcoma; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Up-Regulation	1999
Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells. Journal of cell science, 2001, Volume: 114, Issue:Pt 2 Topics: Animals; Bacterial Proteins; Cell Cycle; Cell Line; Colchicine; DNA Replication; DNA, Mitochondrial; Electron Transport Complex IV; G2 Phase; Genes, Reporter; Humans; Intracellular Membranes; Kinetics; Luminescent Proteins; Mammals; Membrane Potentials; Microtubules; Mitochondria; Mitochondria, Liver; Mitosis; Nocodazole; Osteosarcoma; Paclitaxel; Rats; Transfection	2001
Selective drug resistant human osteosarcoma cell lines. Clinical orthopaedics and related research, 2001, Issue:383 Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Docetaxel; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Immunohistochemistry; Osteosarcoma; Paclitaxel; Taxoids; Tumor Cells, Cultured	2001
[Docitaxol-induction apoptosis of osteosarcoma]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2001, Volume: 23, Issue:3 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; Docetaxel; Humans; Osteosarcoma; Paclitaxel; Taxoids; Tumor Cells, Cultured	2001
Characterization of isotype-specific regions of five classes of canine beta-tubulin and their expression in several tissues and cell culture. The Journal of veterinary medical science, 2001, Volume: 63, Issue:12 Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Dog Diseases; Dogs; Female; Gene Expression Regulation, Neoplastic; Male; Mammary Neoplasms, Animal; Mice; Mice, SCID; Molecular Sequence Data; Osteosarcoma; Paclitaxel; Polymerase Chain Reaction; Protein Isoforms; Sequence Homology, Amino Acid; Tubulin; Tumor Cells, Cultured	2001
[An autopsy case of pulmonary and central nervous system metastatic osteosarcoma treated with thirty-six courses of chemotherapy over four years]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2002, Volume: 40, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carboplatin; Cisplatin; Dacarbazine; Deoxycytidine; Docetaxel; Drug Administration Schedule; Etoposide; Gemcitabine; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Paclitaxel; Spinal Cord Neoplasms; Survivors; Taxoids; Vincristine; Vindesine	2002
Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells. Cytokine, 2002, Mar-07, Volume: 17, Issue:5 Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Blotting, Western; Caspase 3; Caspases; Cell Division; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Genetic Vectors; Humans; Interleukin-6; Interleukin-8; Mitoxantrone; Osteosarcoma; Paclitaxel; Phenotype; RNA; Tetrazolium Salts; Thiazoles; Time Factors; Topotecan; Transfection; Tumor Cells, Cultured	2002
Experimental antitumor activity of taxotere (RP 56976, NSC 628503), a taxol analogue. Cancer research, 1991, Sep-15, Volume: 51, Issue:18 Topics: Adenocarcinoma; Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Intraductal, Noninfiltrating; Colonic Neoplasms; Docetaxel; Female; Leukemia, Experimental; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Osteosarcoma; Paclitaxel; Pancreatic Neoplasms; Sarcoma, Experimental; Taxoids	1991