paclitaxel has been researched along with Nerve Degeneration in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (40.00) | 29.6817 |
| 2010's | 16 (53.33) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Avizonis, D; Bergholz, JS; Chen, CY; de Sá Tavares Russo, M; DiAntonio, A; Hsueh, YP; Jiang, T; Ko, KW; Li, Y; Milbrandt, J; Pazyra-Murphy, MF; Segal, RA; Tang, S; Zhao, JJ; Zhu, J | 1 |
| Bhattacharya, MRC | 1 |
| Barclay, LA; Bird, GH; Fenstermacher, SJ; Fukuda, Y; Li, Y; Pazyra-Murphy, MF; Pease-Raissi, SE; Segal, RA; Wachter, F; Walensky, LD | 1 |
| Au, NPB; Chine, VB; Kumar, G; Ma, CHE | 1 |
| Boucher, M; Cook, JC; Fenyk-Melody, J; Liu, CN; Mechanic, J; Pardo, ID; Peng, Q; Schaevitz, L; Shoieb, A; Somps, C; Vitsky, A | 1 |
| Chen, W; Höke, A; Mi, R; Reed, N; Zhou, C; Zhu, J | 1 |
| Gornstein, E; Schwarz, TL | 1 |
| Dittmann, J; King, AE; Southam, KA; Vickers, JC | 1 |
| Höke, A; Ray, M | 1 |
| Hsieh, YL; Hu, ME; Ko, MH; Lan, CT; Tseng, TJ | 1 |
| Farah, MH; Rammelkamp, Z; Slusher, AB; Slusher, BS; Tasnim, A; Wozniak, K | 1 |
| Bramley, JC; Buchser, WJ; Clark, KB; Collins, SV | 1 |
| Höke, A; Hosmane, S; Siddique, R; Thakor, N; Yang, IH | 1 |
| Bennett, GJ; Jin, HW; Liu, GK; Siau, C; Xiao, WH | 1 |
| Shemesh, OA; Spira, ME | 1 |
| Farah, MH; Ferraris, D; Griffin, JW; Hoffman, PN; Nguyen, T; Pan, BH; Price, DL; Slusher, BS; Tsukamoto, T; Wong, PC | 1 |
| Bhattacharya, MR; DiAntonio, A; Ebstein, SY; Gerdts, J; Milbrandt, J; Naylor, SA; Royse, EX; Sasaki, Y | 1 |
| Das, V; Miller, JH | 1 |
| Fujiwara, T; Morimoto, K | 1 |
| Culver, DG; Davis, AA; Glass, JD; Powers, JC; Wang, MS; Wang, Q | 1 |
| Ansar, S; Audus, KL; Chen, Y; Georg, GI; Himes, RH; Michaelis, ML; Reiff, ER; Seyb, KI | 1 |
| Feinstein, SC; Wilson, L | 1 |
| Feng, J; Jiang, H; Jiang, Q; Liu, W; Ren, Y | 1 |
| Lee, VM; Trojanowski, JQ | 1 |
| Höke, A; Jack, C; Lambrinos, GL; Melli, G; Ringkamp, M | 1 |
| Koike, T; Suzuki, K | 1 |
| Bradke, F; Enes, J; Ertürk, A; Hellal, F | 1 |
| Eguchi, K; Kato, H; Mimura, Y; Ogawa, T | 1 |
| Braguer, D; Briand, C; Carles, G; Delacourte, A; Guise, S | 1 |
| Cheema, SS; Kilpatrick, TJ; Lopes, EC; Phan, S; Reardon, K | 1 |
4 review(s) available for paclitaxel and Nerve Degeneration
| Article | Year |
|---|---|
The paradox of paclitaxel neurotoxicity: Mechanisms and unanswered questions.
Topics: Animals; Axons; Dose-Response Relationship, Drug; Humans; Microtubules; Nerve Degeneration; Paclitaxel | 2014 |
Rodent models of chemotherapy-induced peripheral neuropathy.
Topics: Animals; Antineoplastic Agents; Axons; Boronic Acids; Bortezomib; Cisplatin; Disease Models, Animal; Mice; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases; Pyrazines; Rats; Vincristine | 2014 |
Inability of tau to properly regulate neuronal microtubule dynamics: a loss-of-function mechanism by which tau might mediate neuronal cell death.
Topics: Cell Death; Colchicine; Dementia; Humans; Microtubules; Models, Biological; Nerve Degeneration; Neurons; Paclitaxel; tau Proteins | 2005 |
Progress from Alzheimer's tangles to pathological tau points towards more effective therapies now.
Topics: Alzheimer Disease; Antineoplastic Agents, Phytogenic; Brain; Disease Progression; Humans; Nerve Degeneration; Neurofibrillary Tangles; Paclitaxel; tau Proteins | 2006 |
26 other study(ies) available for paclitaxel and Nerve Degeneration
| Article | Year |
|---|---|
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN.
Topics: Animals; Armadillo Domain Proteins; Axons; Calcium; Calcium Channels; Cyclic ADP-Ribose; Cytoskeletal Proteins; Female; HEK293 Cells; Humans; Mice, Inbred C57BL; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases; Rats, Sprague-Dawley | 2022 |
A Chemotherapy-Induced Peripheral Neuropathy Model in Drosophila melanogaster.
Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents; Axons; Dendrites; Disease Models, Animal; Dissection; Drosophila melanogaster; Female; Genotype; Larva; Male; Microscopy, Fluorescence; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases | 2020 |
Paclitaxel Reduces Axonal Bclw to Initiate IP
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Axons; Cells, Cultured; Female; Ganglia, Spinal; Inositol 1,4,5-Trisphosphate Receptors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2017 |
Targeting Axon Integrity to Prevent Chemotherapy-Induced Peripheral Neuropathy.
Topics: Actin Depolymerizing Factors; Action Potentials; Animals; Antineoplastic Agents; Apoptosis; Axons; Caspase 3; Ganglia, Spinal; HSP27 Heat-Shock Proteins; Humans; Hyperalgesia; Male; Mice, Transgenic; Mitochondria; Mitochondrial Swelling; Myelin Sheath; Nerve Degeneration; Nerve Fibers; Neuroprotective Agents; Paclitaxel; Peripheral Nervous System Diseases; rhoA GTP-Binding Protein; Signal Transduction | 2019 |
Circulating microRNA and automated motion analysis as novel methods of assessing chemotherapy-induced peripheral neuropathy in mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Automation; Behavior, Animal; Biomarkers; Circulating MicroRNA; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Movement; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases; Sciatic Nerve | 2019 |
Ethoxyquin prevents chemotherapy-induced neurotoxicity via Hsp90 modulation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Axons; Cell Line; Drug Evaluation, Preclinical; Ethoxyquin; HSP90 Heat-Shock Proteins; Male; Mice; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Paclitaxel | 2013 |
Excitotoxin-induced caspase-3 activation and microtubule disintegration in axons is inhibited by taxol.
Topics: Animals; Axons; Caspase 3; Cells, Cultured; Cerebral Cortex; Cytoskeleton; Dendrites; Dose-Response Relationship, Drug; Kainic Acid; Mice; Microtubule-Associated Proteins; Microtubules; Nerve Degeneration; Neuroprotective Agents; Paclitaxel; Wallerian Degeneration | 2013 |
Peptidergic intraepidermal nerve fibers in the skin contribute to the neuropathic pain in paclitaxel-induced peripheral neuropathy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Calcitonin Gene-Related Peptide; Epidermis; Male; Nerve Degeneration; Nerve Fibers; Neuralgia; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Substance P | 2014 |
Paclitaxel causes degeneration of both central and peripheral axon branches of dorsal root ganglia in mice.
Topics: Animals; Antineoplastic Agents; Axons; Disease Models, Animal; Female; Ganglia, Spinal; Male; Mice, Inbred C57BL; Microscopy, Electron; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases; Sciatic Nerve; Spinal Cord | 2016 |
Avian axons undergo Wallerian degeneration after injury and stress.
Topics: Analysis of Variance; Animals; Axons; Axotomy; Calcium; Cells, Cultured; Disease Models, Animal; Finches; Microscopy, Confocal; Microscopy, Fluorescence; NAD; Nerve Degeneration; Paclitaxel; Pressure; Retinal Ganglion Cells; Stress, Physiological; Vincristine; Wallerian Degeneration | 2016 |
Compartmentalized microfluidic culture platform to study mechanism of paclitaxel-induced axonal degeneration.
Topics: Animals; Antineoplastic Agents, Phytogenic; Axons; Cell Count; Cells, Cultured; Embryo, Mammalian; Erythropoietin; Fluoresceins; Ganglia, Spinal; Microfluidics; Nerve Degeneration; Paclitaxel; Rats; Recombinant Proteins; Sensory Receptor Cells | 2009 |
Terminal arbor degeneration--a novel lesion produced by the antineoplastic agent paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Epidermis; Male; Nerve Degeneration; Nerve Fibers; Neuralgia; Paclitaxel; Pain Measurement; Peripheral Nerves; Rats; Rats, Sprague-Dawley | 2011 |
Rescue of neurons from undergoing hallmark tau-induced Alzheimer's disease cell pathologies by the antimitotic drug paclitaxel.
Topics: Alzheimer Disease; Animals; Aplysia; Cells, Cultured; Humans; Mitosis; Nerve Degeneration; Neurons; Paclitaxel; Protein Unfolding; tau Proteins; Tauopathies; Transduction, Genetic; Tubulin Modulators | 2011 |
Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system.
Topics: Acrylamide; Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents, Phytogenic; Aspartic Acid Endopeptidases; Axons; Biotin; Enzyme Inhibitors; Ganglia, Spinal; Immunohistochemistry; Infusion Pumps, Implantable; Mice; Mice, 129 Strain; Mice, Knockout; Microscopy, Electron; Myelin Sheath; Nerve Degeneration; Nerve Regeneration; Neuromuscular Junction; Paclitaxel; Peripheral Nervous System; Phagocytosis; Sciatic Nerve; Wallerian Degeneration | 2011 |
A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Axons; Disease Models, Animal; Drosophila; Drosophila Proteins; Eye Proteins; Female; Ganglia, Spinal; Immunohistochemistry; Larva; Mice; Microscopy, Confocal; Nerve Degeneration; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nerves; RNA Interference | 2012 |
Microtubule stabilization by peloruside A and paclitaxel rescues degenerating neurons from okadaic acid-induced tau phosphorylation.
Topics: Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Female; Lactones; Male; Microtubules; Nerve Degeneration; Neuroprotective Agents; Paclitaxel; Phosphorylation; Primary Cell Culture; Rats; Rats, Sprague-Dawley; tau Proteins; Tubulin Modulators | 2012 |
Inhibition of p53 transactivation functionally interacts with microtubule stabilization to suppress excitotoxicity-induced axon degeneration.
Topics: Animals; Axons; Benzothiazoles; Cells, Cultured; Dynactin Complex; Glutamic Acid; Hippocampus; Microtubule-Associated Proteins; Microtubules; Mitochondria; Mitochondrial Diseases; Nerve Degeneration; Neurotoxins; Paclitaxel; Rats; Rats, Wistar; Toluene; Transcriptional Activation; Tumor Suppressor Protein p53 | 2012 |
Calpain inhibition protects against Taxol-induced sensory neuropathy.
Topics: Animals; Antineoplastic Agents; Axons; Calpain; Caspases; Cell Death; Cell Line; Cells, Cultured; Dipeptides; Electrophysiology; Female; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microtubules; Nerve Degeneration; Neurons, Afferent; Paclitaxel; Rats; Rats, Inbred Strains | 2004 |
{beta}-Amyloid-induced neurodegeneration and protection by structurally diverse microtubule-stabilizing agents.
Topics: Amyloid beta-Peptides; Animals; Antineoplastic Agents, Phytogenic; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; JNK Mitogen-Activated Protein Kinases; Kinetics; Microtubules; Nerve Degeneration; Neurons; Neuroprotective Agents; Paclitaxel; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2005 |
Selective vulnerability of dopaminergic neurons to microtubule depolymerization.
Topics: Cell Death; Colchicine; Cytosol; Dopamine; Humans; Microtubules; Nerve Degeneration; Nocodazole; Oxidative Stress; Paclitaxel; Parkinson Disease; Polymers; Receptors, Dopamine; Rotenone; Substantia Nigra; Uncoupling Agents | 2005 |
Erythropoietin protects sensory axons against paclitaxel-induced distal degeneration.
Topics: Animals; Antineoplastic Agents, Phytogenic; Axons; Cells, Cultured; Dose-Response Relationship, Drug; Drug Carriers; Erythropoietin; Female; Ganglia, Spinal; Glycerol; Humans; Injections, Intraperitoneal; Mice; Nerve Degeneration; Neurons, Afferent; Neuroprotective Agents; Paclitaxel; Recombinant Proteins; Tubulin; Tyrosine | 2006 |
Mammalian Sir2-related protein (SIRT) 2-mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: a crucial role of tubulin deacetylation.
Topics: Acetylation; Analysis of Variance; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Cerebellum; Colchicine; Fluoresceins; Gene Expression Regulation, Enzymologic; Mice; Nerve Degeneration; Neurons; Paclitaxel; RNA, Small Interfering; Sirtuin 2; Sirtuins; Time Factors; Transfection; Tubulin; Tubulin Modulators; Wallerian Degeneration | 2007 |
Disorganized microtubules underlie the formation of retraction bulbs and the failure of axonal regeneration.
Topics: Animals; Axons; Cells, Cultured; Central Nervous System; Cerebellum; Ganglia, Spinal; Green Fluorescent Proteins; Growth Cones; Luminescent Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Microtubules; Nerve Degeneration; Neurons; Nocodazole; Paclitaxel; Regeneration; Sciatic Neuropathy; Tubulin Modulators | 2007 |
Schedule dependency of paclitaxel-induced neuropathy in mice: a morphological study.
Topics: Action Potentials; Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Body Weight; Electrophysiology; Ganglia, Spinal; Injections, Intraperitoneal; Male; Mice; Nerve Degeneration; Nerve Fibers; Neuropeptides; Neurotoxicity Syndromes; Paclitaxel; Pain Threshold; Sciatic Nerve | 2000 |
Hyperphosphorylation of tau is mediated by ERK activation during anticancer drug-induced apoptosis in neuroblastoma cells.
Topics: Alzheimer Disease; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Doxorubicin; Humans; Microtubules; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neuroblastoma; Paclitaxel; Phosphorylation; tau Proteins; Tumor Cells, Cultured | 2001 |
Leukaemia inhibitory factor abrogates Paclitaxel-induced axonal atrophy in the Wistar rat.
Topics: Animals; Antineoplastic Agents, Phytogenic; Axons; Calcitonin Gene-Related Peptide; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Spinal; Growth Inhibitors; Immunohistochemistry; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Nerve Degeneration; Neural Conduction; Neurons, Afferent; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Substance P | 2001 |