Compounds > paclitaxel
Page last updated: 2024-08-23

paclitaxel and Nasopharyngeal Carcinoma

paclitaxel has been researched along with Nasopharyngeal Carcinoma in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's37 (72.55)24.3611
2020's14 (27.45)2.80

Authors

AuthorsStudies
Chen, Y; Ding, X; Feng, G; Huang, Y; Lin, L; Ma, S; Wang, R; Xu, R; Yang, Y; Zhang, C; Zhang, L; Zhou, T1
Cao, KJ; Chen, MY; Chen, QY; Chen, ZJ; Guo, L; Guo, X; Hu, D; Hua, YJ; Huang, PY; Ke, LR; Li, WZ; Liang, H; Liu, GY; Liu, T; Lu, N; Luo, DH; Lv, SH; Lv, X; Mai, HQ; Mo, HY; Qian, CN; Qiu, F; Sun, R; Tang, LQ; Tang, WB; Tong, LH; Wang, DS; Wang, L; Xia, WX; Xiang, YQ; Yang, W; Ye, YF; Yuan, TZ; Zhang, HX; Zhao, C1
Li, X; Lu, W; Yang, L; Zhao, F; Zhou, T1
Cao, K; Chen, H; Cheng, Y; Wang, Z; Xiao, M; Zhang, Y; Zhu, Y1
Li, X; Ling, F; Long, W; Sun, X; Xu, S1
Chen, Y; Cui, X; Ding, X; Zhao, L1
Jiang, B; Li, Y; Ni, H; Zhou, Z1
Li, H; Li, W; Peng, X; Song, Y; Tan, G; Wang, F; Wang, X; Xie, J1
Chuan, Z; Hui, Z; Jiafeng, Z; Miaomiao, Z; Ping, H; Qiongna, D; Xiaojie, J; Yalin, H; Yiting, S1
Zhu, H1
Li, H; Song, Y; Wang, K; Wang, X; Xiao, J1
Yuan, F; Zhou, ZF1
Fan, Z; Gui, G; Ning, Y; Xu, Q; Yuan, C; Zhang, B1
Hu, J; Hu, L; Jiang, B; Jiang, M; Liu, X; Pan, X; Zeng, H1
Hao, S; Wang, Q; Zhang, W1
Fong, KW; Hussain, A; Ong, WS; Sommat, K; Soong, YL; Tan, T; Wee, J1
Fu, T; Gao, J; Shao, Z; Yan, M; Yan, Y; Zhang, L1
Hu, WH; Jin, T; Li, PJ; Luo, DH; Mo, HY1
Li, B; Liao, W; Wen, H; Xu, P; Zhang, S; Zheng, L1
Chen, QY; Guo, L; Guo, SS; Li, XY; Liang, YJ; Lin, C; Lin, HX; Liu, LT; Liu, SL; Mai, HQ; Sun, XS; Tang, LQ; Tang, QN; Wen, YF; Xie, HJ; Yan, JJ; Yang, ZC1
Bo, H; Cao, K; Gong, L; He, D; Li, R; Li, W; Liu, X; Liu, Y; Liu, Z; Ma, Y; Xiang, L; Xiao, M; Xing, X; Xiong, W; Yang, F; Zhou, J; Zhou, M; Zhou, Y; Zhu, Y1
Chan, AT; Cheng, SH; Cheung, CS; Ho, K; Hui, CW; Hui, EP; Lau, CP; Lui, VW; Ma, BB; Ng, MH; Tsang, CM; Tsao, SW; Wong, CH1
Chen, X; Mou, J; Pan, X; Peng, G; Zou, Z1
Li, G; Liu, Y; Qiu, Y; Ren, S; Su, Z; Tan, P; Tian, Y; Wang, Y; Zhang, X1
Cao, K; Cao, P; Han, S; He, D; Li, W; Li, Z; Peng, X; Tan, G; Yu, F; Yu, J; Zhou, J1
Cao, Y; Gao, J; Huang, J; Liu, M; Sun, L; Tang, M; Wang, X; Weng, X; Yang, L; Yi, W; Zeng, W; Zhou, M1
Cao, K; Cao, P; Han, S; He, D; Li, J; Li, W; Li, Z; Peng, X; Tan, G; Yu, F; Yu, J; Zhou, J1
Ang, MK; Cheah, SL; Fong, KW; Lim, WT; Ng, QS; Ong, WS; Quah, D; Soo, KC; Soong, YL; Tan, D; Tan, SH; Tan, T; Wee, J; Yip, C1
Ding, N; Feng, D; Liu, Q; Sun, LQ; Tan, G; Wang, X; Xie, B; Yang, X; Zhang, J; Zhang, L; Zhou, Z1
Hou, C; Tan, T; Yang, N; Zhu, L1
Hidaka, T; Ishiguro, Y; Kameda, T; Kamiunten, A; Kawabata, T; Kitanaka, A; Kubuki, Y; Miyaushiro, S; Sekine, M; Shide, K; Shimoda, K; Umekita, Y1
Lan, XW; Mao, YP; OuYang, PY; Su, Z; Tang, J; Xie, FY1
Li, W; Peng, X; Qin, J; Song, Y; Tan, G; Xiang, H; You, Y; Zhang, X1
Li, T1
Li, G; Liu, C; Liu, Y; Qiu, Y; Ren, S; Su, Z; Tian, Y1
Chen, S; Chen, X; Liao, Y; Lin, X; Long, D; Shen, F; Yu, T; Zhang, L1
Jiang, YX; Li, YH; Liang, Y; Luo, HY; Wang, DS; Wang, FH; Wang, Y; Wang, ZQ1
Huang, Y; Liang, W; Wu, X; Yang, Y; Zhang, L; Zhang, Y; Zhao, H; Zhao, L; Zhao, Y1
Cai, T; Li, G; Liu, C; Liu, Y; Qiu, Y; Ren, S; She, L; Su, Z; Tian, Y; Wang, Y; Wei, M; Zhang, X1
Duan, Y; Fan, X; Gong, Z; Gulina, K; Hou, Y; Jiang, Z; Li, J; Li, X; Li, Z; Liu, Y; Peng, Y; Sun, L; Tan, G; Xie, B; Yin, L; Yu, X; Yuan, B; Zhu, Q1
Athanassiou, H; Bobos, M; Ciuleanu, E; Ciuleanu, T; Dionysopoulos, D; Eleftheraki, AG; Fountzilas, G; Kalogera-Fountzila, A; Karayannopoulou, G; Markou, K; Misailidou, D; Nikolaou, A; Resiga, L; Samantas, E; Skarlos, D; Zaramboukas, T1
He, G; Li, H; Li, W; Ma, Y; Tan, G1
Cai, XY; Cai, YC; Cao, Y; Hu, WH; Jiang, WQ; Jin, Y; Shi, YX; Xia, XY; Zhang, WD1
Guo, Y; Huang, D; Li, G; Li, S; Liu, Y; Qiu, Y; Tan, P; Tian, Y; Xiao, J; Zhang, X1
Huang, WL; Li, XY; Lin, SL; Lin, W; Lin, WZ; Lin, YC; Wang, HB1
He, G; Li, H; Li, W; Ma, Y; Tan, G; Zhang, X1
Drage, MG; Haddad, RI; Lichtman, AH; Shah, SM1
An, X; Chen, C; Li, YH; Liang, Y; Luo, HY; Wang, FH; Wang, ZQ; Zhang, L1
Chan, AT; Hui, CW; Hui, EP; Lau, CP; Li, Y; Lui, VW; Ma, BB; Ng, MH; Tsao, SW; Wong, CH1
Jiang, C; Jiang, Z; Liu, H; Pu, L; Song, L; Zhang, P; Zhao, S1
He, CX; Jin, Y; Lin, BC; Shao, L; Ye, X; Zhang, BB; Zhang, YP1

Trials

7 trial(s) available for paclitaxel and Nasopharyngeal Carcinoma

ArticleYear
Bevacizumab versus placebo in combination with paclitaxel and carboplatin as first-line treatment for recurrent or metastatic nasopharyngeal carcinoma: a multicentre, randomised, open-label, phase II trial.
    ESMO open, 2021, Volume: 6, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Humans; Lung Neoplasms; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Paclitaxel

2021
Effect of Induction Chemotherapy With Paclitaxel, Cisplatin, and Capecitabine vs Cisplatin and Fluorouracil on Failure-Free Survival for Patients With Stage IVA to IVB Nasopharyngeal Carcinoma: A Multicenter Phase 3 Randomized Clinical Trial.
    JAMA oncology, 2022, 05-01, Volume: 8, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cisplatin; Fluorouracil; Humans; Induction Chemotherapy; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Paclitaxel

2022
Thyroid V40 Predicts Primary Hypothyroidism After Intensity Modulated Radiation Therapy for Nasopharyngeal Carcinoma.
    International journal of radiation oncology, biology, physics, 2017, 07-01, Volume: 98, Issue:3

    Topics: Adult; Age Factors; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chemoradiotherapy; Cisplatin; Deoxycytidine; Female; Follow-Up Studies; Gemcitabine; Humans; Hypothyroidism; Incidence; Induction Chemotherapy; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Pituitary Gland; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Regression Analysis; Thyroid Gland; Time Factors

2017
Concurrent chemo-radiation with or without induction gemcitabine, Carboplatin, and Paclitaxel: a randomized, phase 2/3 trial in locally advanced nasopharyngeal carcinoma.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chemoradiotherapy; Cisplatin; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Induction Chemotherapy; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Patient Compliance; Quality of Life; Radiation-Sensitizing Agents

2015
Phase I/II dose-finding study of nanoparticle albumin-bound paclitaxel (nab®-Paclitaxel) plus Cisplatin as Treatment for Metastatic Nasopharyngeal Carcinoma.
    BMC cancer, 2016, 07-13, Volume: 16

    Topics: Adult; Albumin-Bound Paclitaxel; Albumins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Immunohistochemistry; Male; Maximum Tolerated Dose; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Osteonectin; Paclitaxel; Treatment Outcome

2016
Induction chemotherapy followed by concomitant radiotherapy and weekly cisplatin versus the same concomitant chemoradiotherapy in patients with nasopharyngeal carcinoma: a randomized phase II study conducted by the Hellenic Cooperative Oncology Group (HeC
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma; Chemoradiotherapy; Cisplatin; Epirubicin; Female; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Ki-67 Antigen; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Prognosis; Proportional Hazards Models; Tumor Suppressor Protein p53; Young Adult

2012
Triplet combination with paclitaxel, cisplatin and 5-FU is effective in metastatic and/or recurrent nasopharyngeal carcinoma.
    Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Female; Fluorouracil; Humans; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Paclitaxel; Prognosis

2013

Other Studies

44 other study(ies) available for paclitaxel and Nasopharyngeal Carcinoma

ArticleYear
Timosaponin AIII Suppresses RAP1 Signaling Pathway to Enhance the Inhibitory Effect of Paclitaxel on Nasopharyngeal Carcinoma.
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Guanine Nucleotide Exchange Factors; Humans; Mice; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Saponins; Signal Transduction; Steroids; Xenograft Model Antitumor Assays

2022
circRNA_0067717 promotes paclitaxel resistance in nasopharyngeal carcinoma by acting as a scaffold for TRIM41 and p53.
    Cellular oncology (Dordrecht), 2023, Volume: 46, Issue:3

    Topics: Cell Line, Tumor; Cell Proliferation; Humans; In Situ Hybridization, Fluorescence; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; RNA, Circular; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases

2023
Cytoplasmic poly(A)-binding protein 1 (PABPC1) is a prognostic biomarker to predict survival in nasopharyngeal carcinoma regardless of chemoradiotherapy.
    BMC cancer, 2023, Feb-20, Volume: 23, Issue:1

    Topics: Chemoradiotherapy; Humans; Induction Chemotherapy; Ki-67 Antigen; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Poly(A)-Binding Protein I; Poly(A)-Binding Proteins; Prognosis; Tumor Suppressor Protein p53

2023
Extracellular vesicles derived from paclitaxel-sensitive nasopharyngeal carcinoma cells deliver miR-183-5p and impart paclitaxel sensitivity through a mechanism involving P-gp.
    Cell biology and toxicology, 2023, Volume: 39, Issue:6

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Extracellular Vesicles; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel

2023
Parkin enhances sensitivity of paclitaxel to NPC by arresting cell cycle.
    Pathology, research and practice, 2020, Volume: 216, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Ubiquitin-Protein Ligases

2020
The role of Caspase-1/GSDMD-mediated pyroptosis in Taxol-induced cell death and a Taxol-resistant phenotype in nasopharyngeal carcinoma regulated by autophagy.
    Cell biology and toxicology, 2020, Volume: 36, Issue:5

    Topics: Autophagy; Caspase 1; Caspase Inhibitors; Cell Line, Tumor; Down-Regulation; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Nasopharyngeal Carcinoma; Necrosis; Paclitaxel; Phenotype; Phosphate-Binding Proteins; Pyroptosis

2020
Implication of hsa_circ_0028007 in reinforcing migration, invasion, and chemo-tolerance of nasopharyngeal carcinoma cells.
    Journal of clinical laboratory analysis, 2020, Volume: 34, Issue:9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Drug Resistance, Neoplasm; Female; Humans; Male; MicroRNAs; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Nose; Paclitaxel

2020
Silencing long non-coding RNA H19 combined with paclitaxel inhibits nasopharyngeal carcinoma progression.
    International journal of pediatric otorhinolaryngology, 2020, Volume: 138

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Disease Progression; Gene Silencing; Humans; Mice; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; RNA, Long Noncoding; Xenograft Model Antitumor Assays

2020
Neferine sensitized Taxol-resistant nasopharygeal carcinoma to Taxol by inhibiting EMT via downregulating miR-130b-5p.
    Biochemical and biophysical research communications, 2020, 10-22, Volume: 531, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzylisoquinolines; Cell Line, Tumor; Cell Movement; Down-Regulation; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Male; Mice, Inbred BALB C; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays

2020
Exosomes derived from Taxol-resistant nasopharyngeal carcinoma (NPC) cells transferred DDX53 to NPC cells and promoted cancer resistance to Taxol.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:1

    Topics: Aniline Compounds; Antineoplastic Agents, Phytogenic; Benzylidene Compounds; DEAD-box RNA Helicases; Drug Resistance, Neoplasm; Exosomes; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Tumor Cells, Cultured

2021
Optimization, Characterization and in vivo Evaluation of Paclitaxel-Loaded Folate-Conjugated Superparamagnetic Iron Oxide Nanoparticles.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Drug Liberation; Folic Acid; Humans; Imines; Inhibitory Concentration 50; Magnetic Iron Oxide Nanoparticles; Nasopharyngeal Carcinoma; Paclitaxel; Particle Size; Polyethylene Glycols; Polyethylenes; Rats; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Static Electricity; Succinates; Tissue Distribution

2021
Proteasome inhibitors decrease paclitaxel‑induced cell death in nasopharyngeal carcinoma with the accumulation of CDK1/cyclin B1.
    International journal of molecular medicine, 2021, Volume: 48, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cyclin B1; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Proteasome Inhibitors; Signal Transduction

2021
LncRNA CCAT1 modulates the sensitivity of paclitaxel in nasopharynx cancers cells via miR-181a/CPEB2 axis.
    Cell cycle (Georgetown, Tex.), 2017, Apr-18, Volume: 16, Issue:8

    Topics: Base Sequence; Carcinoma; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; MicroRNAs; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; RNA-Binding Proteins; RNA, Long Noncoding; Signal Transduction; Up-Regulation

2017
Targeted regulationof STAT3 by miR-29a in mediating Taxol resistance of nasopharyngeal carcinoma cell line CNE-1.
    Cancer biomarkers : section A of Disease markers, 2018, Volume: 22, Issue:4

    Topics: Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; STAT3 Transcription Factor

2018
The efficacy of induction chemotherapy in the treatment of stage II nasopharyngeal carcinoma in intensity modulated radiotherapy era.
    Oral oncology, 2018, Volume: 85

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Chemoradiotherapy; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Hematologic Neoplasms; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Paclitaxel; Progression-Free Survival; Proportional Hazards Models; Radiotherapy, Intensity-Modulated; Retrospective Studies; Treatment Outcome

2018
Tumor Volume Reduction After Gemcitabine Plus Cisplatin Induction Chemotherapy in Locally Advanced Nasopharyngeal Cancer: Comparison with Paclitaxel and Cisplatin Regimens.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Nov-08, Volume: 24

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; China; Cisplatin; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Induction Chemotherapy; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Staging; Paclitaxel; Retrospective Studies; Survival Analysis; Tumor Burden

2018
Liposomal paclitaxel versus docetaxel in induction chemotherapy using Taxanes, cisplatin and 5-fluorouracil for locally advanced nasopharyngeal carcinoma.
    BMC cancer, 2018, Dec-20, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Cell Line, Tumor; Cisplatin; Disease-Free Survival; Docetaxel; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Herpesvirus 4, Human; Humans; Liposomes; Male; Middle Aged; Nasopharyngeal Carcinoma; Neoplasm Recurrence, Local; Neutropenia; Paclitaxel; Taxoids

2018
The MRVI1-AS1/ATF3 signaling loop sensitizes nasopharyngeal cancer cells to paclitaxel by regulating the Hippo-TAZ pathway.
    Oncogene, 2019, Volume: 38, Issue:32

    Topics: A549 Cells; Activating Transcription Factor 3; Acyltransferases; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hippo Signaling Pathway; Humans; MCF-7 Cells; Membrane Proteins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Phosphoproteins; Protein Serine-Threonine Kinases; RNA, Antisense; Signal Transduction; Transcription Factors

2019
Preclinical evaluation of the mTOR-PI3K inhibitor BEZ235 in nasopharyngeal cancer models.
    Cancer letters, 2014, Feb-01, Volume: 343, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Cycle; Cell Line, Tumor; Cell Survival; Cisplatin; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Inhibitory Concentration 50; MAP Kinase Signaling System; Mice; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolines; TOR Serine-Threonine Kinases

2014
[Preliminary mechanism of paclitaxel enhanced radiation sensitivity for nasopharyngeal carcinoma cells].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2014, Volume: 28, Issue:15

    Topics: Apoptosis; Carcinoma; Cell Cycle; Cell Line, Tumor; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Radiation Tolerance

2014
Ephrin type‑A receptor 2 regulates sensitivity to paclitaxel in nasopharyngeal carcinoma via the phosphoinositide 3‑kinase/Akt signalling pathway.
    Molecular medicine reports, 2015, Volume: 11, Issue:2

    Topics: Animals; Apoptosis; Carcinoma; Cell Line, Tumor; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rabbits; Receptor, EphA2; Signal Transduction

2015
MiR-634 sensitizes nasopharyngeal carcinoma cells to paclitaxel and inhibits cell growth both in vitro and in vivo.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Mice, Nude; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays

2014
Evaluation of a dansyl-based amino acid DNSBA as an imaging probe for apoptosis detection.
    Apoptosis : an international journal on programmed cell death, 2015, Volume: 20, Issue:3

    Topics: Animals; Annexin A5; Apoptosis; Biological Transport; Carcinoma; Caspases; Cell Line, Tumor; Cell Membrane Permeability; Dansyl Compounds; Gene Expression; Humans; In Situ Nick-End Labeling; Injections, Subcutaneous; Kinetics; Mice; Mice, Inbred BALB C; Molecular Probes; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Optical Imaging; Paclitaxel; Phenylpropionates; Tumor Necrosis Factor-alpha

2015
MiR-1204 sensitizes nasopharyngeal carcinoma cells to paclitaxel both in vitro and in vivo.
    Cancer biology & therapy, 2015, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays

2015
FOXC2 promotes chemoresistance in nasopharyngeal carcinomas via induction of epithelial mesenchymal transition.
    Cancer letters, 2015, Jul-28, Volume: 363, Issue:2

    Topics: Animals; Anoikis; Carcinoma; Cell Proliferation; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Mice; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel

2015
[Study of the relationship among expression of Survivin and MRP and the drug resistance in human nasopharyngeal carcinoma].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2015, Volume: 29, Issue:3

    Topics: Antineoplastic Agents; Carcinoma; Cisplatin; Drug Resistance, Neoplasm; Fluorouracil; Humans; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Lymphatic Metastasis; Multidrug Resistance-Associated Proteins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Nasopharynx; Paclitaxel; Survivin; Vincristine

2015
Nasopharyngeal carcinoma with bone marrow metastasis: positive response to weekly paclitaxel chemotherapy.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:11

    Topics: Bone Marrow Neoplasms; Carcinoma; Humans; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Paclitaxel

2015
Long-term outcomes of concurrent chemoradiotherapy versus radiotherapy alone in stage II nasopharyngeal carcinoma treated with IMRT: a retrospective study.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradiotherapy; Cisplatin; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Staging; Paclitaxel; Prognosis; Proportional Hazards Models; Radiotherapy, Intensity-Modulated; Retrospective Studies; Treatment Outcome

2016
Amplification of chromosome 8q21-qter associated with the acquired paclitaxel resistance of nasopharyngeal carcinoma cells.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:10

    Topics: Angiopoietin-1; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinoma; Cell Line, Tumor; Chromosomes, Human, Pair 8; Comparative Genomic Hybridization; Drug Resistance, Neoplasm; Gene Amplification; Gene Expression Profiling; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Real-Time Polymerase Chain Reaction; Transcriptome

2015
[Pacilitaxel induces human nasopharyngeal carcinoma cell line CNE2 apoptosis and growth inhibition by suppressing PI3K/AKT/p53 signaling pathway].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2015, Volume: 29, Issue:24

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma; Cell Line, Tumor; Flow Cytometry; Humans; Membrane Potentials; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Suppressor Protein p53

2015
Ionizing radiation promotes advanced malignant traits in nasopharyngeal carcinoma via activation of epithelial-mesenchymal transition and the cancer stem cell phenotype.
    Oncology reports, 2016, Volume: 36, Issue:1

    Topics: Antineoplastic Agents; Cadherins; Carcinoma; Cell Line, Tumor; Cell Movement; Cisplatin; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplastic Stem Cells; Paclitaxel; Proto-Oncogene Proteins c-myc; Radiation, Ionizing; Receptors, G-Protein-Coupled; Vimentin

2016
Silencing Op18/stathmin by RNA Interference Promotes the Sensitivity of Nasopharyngeal Carcinoma Cells to Taxol and High-Grade Differentiation of Xenografted Tumours in Nude Mice.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Combined Modality Therapy; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Male; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Grading; Paclitaxel; Random Allocation; RNA Interference; RNAi Therapeutics; Stathmin; Xenograft Model Antitumor Assays

2016
A triplet chemotherapy regimen of cisplatin, fluorouracil and paclitaxel for locoregionally recurrent nasopharyngeal carcinoma cases contraindicated for re-irradiation/surgery.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma; Cisplatin; Disease-Free Survival; Drug Therapy, Combination; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leukopenia; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Neutropenia; Paclitaxel; Prognosis; Re-Irradiation; Treatment Outcome

2016
Next generation deep sequencing identified a novel lncRNA n375709 associated with paclitaxel resistance in nasopharyngeal carcinoma.
    Oncology reports, 2016, Volume: 36, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Drug Resistance, Neoplasm; High-Throughput Nucleotide Sequencing; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Polymerase Chain Reaction; RNA, Long Noncoding; Transfection

2016
The FOXM1-ABCC5 axis contributes to paclitaxel resistance in nasopharyngeal carcinoma cells.
    Cell death & disease, 2017, 03-09, Volume: 8, Issue:3

    Topics: Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Humans; Multidrug Resistance-Associated Proteins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Paclitaxel; Signal Transduction

2017
Inhibition of α folate receptor resulting in a reversal of taxol resistance in nasopharyngeal carcinoma.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2012, Volume: 146, Issue:2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Carcinoma; Drug Resistance, Neoplasm; Folate Receptor 1; Folic Acid; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Tumor Cells, Cultured

2012
Comparison of five cisplatin-based regimens frequently used as the first-line protocols in metastatic nasopharyngeal carcinoma.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Cisplatin; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Gemcitabine; Humans; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Retrospective Studies

2012
[Synergistic interactions of TRAIL and paclitaxel on the nasopharyngeal carcinoma cell lines in vitro].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2012, Volume: 26, Issue:7

    Topics: Apoptosis; Carcinoma; Cell Line, Tumor; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Receptors, TNF-Related Apoptosis-Inducing Ligand

2012
[Study of sequence-dependent in vitro effects of zoledronic acid and paclitaxel upon human nasopharyngeal carcinoma cell line HNE1].
    Zhonghua yi xue za zhi, 2012, Apr-24, Volume: 92, Issue:16

    Topics: Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Humans; Imidazoles; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Zoledronic Acid

2012
Genomic methylation profiling combined with gene expression microarray reveals the aberrant methylation mechanism involved in nasopharyngeal carcinoma taxol resistance.
    Anti-cancer drugs, 2012, Volume: 23, Issue:8

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Azacitidine; Carcinoma; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Profiling; Genomics; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel

2012
Metastatic human papillomavirus-positive nasopharyngeal carcinoma with an unusual pattern of aggressive hematogenous spread.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Nov-10, Volume: 30, Issue:32

    Topics: Alphapapillomavirus; Antineoplastic Combined Chemotherapy Protocols; Axilla; Biomarkers, Tumor; Carboplatin; Carcinoma; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Diagnosis, Differential; Drug Administration Schedule; Fatal Outcome; Fluorodeoxyglucose F18; Fluorouracil; Heart Failure; Humans; Hypertension, Pulmonary; Hypoxia; Immunohistochemistry; Laryngoscopy; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Multimodal Imaging; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Staging; Paclitaxel; Papillomavirus Infections; Positron-Emission Tomography; Pulmonary Artery; Radiopharmaceuticals; Radiotherapy, Intensity-Modulated; Randomized Controlled Trials as Topic; Thrombophilia; Tomography, X-Ray Computed; Vascular Neoplasms

2012
Preclinical evaluation of the AKT inhibitor MK-2206 in nasopharyngeal carcinoma cell lines.
    Investigational new drugs, 2013, Volume: 31, Issue:3

    Topics: Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cisplatin; Heterocyclic Compounds, 3-Ring; Humans; Mitogen-Activated Protein Kinases; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2013
[Effect of low-molecular-weight heparin combined with paclitaxel on the invasiveness and migration of nasopharyngeal carcinoma cells in vitro].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:11

    Topics: Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glucuronidase; Heparin Lyase; Heparin, Low-Molecular-Weight; Humans; Matrix Metalloproteinase 9; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Tissue Inhibitor of Metalloproteinase-1

2012
Serum lactic dehydrogenase strongly predicts survival in metastatic nasopharyngeal carcinoma treated with palliative chemotherapy.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma; Cisplatin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; L-Lactate Dehydrogenase; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Outcome Assessment, Health Care; Paclitaxel; Palliative Care; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Retrospective Studies; Young Adult

2013