Page last updated: 2024-08-23

paclitaxel and Leukemia, Myeloid, Acute

paclitaxel has been researched along with Leukemia, Myeloid, Acute in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.00)18.7374
1990's7 (23.33)18.2507
2000's8 (26.67)29.6817
2010's5 (16.67)24.3611
2020's7 (23.33)2.80

Authors

AuthorsStudies
Chen, L; Gallucci, JC; Kinghorn, AD; Li, X; Ren, Y; Yu, J1
Okines, A; Turner, N1
Geyer, CE; Loibl, S; Sikov, WM1
Aissouni, Y; Balayssac, D; Busserolles, J; Chapuy, E; Collin, A; Condé, S; Dalbos, C; Dumontet, C; Martin, PY; Mattévi, C; Richard, D; Selvy, M1
Bai, ZW; Liu, ZF; Pang, RL; Shi, ZY; Wu, MQ; Yao, YB; Zhao, WH; Zhou, BW1
He, C; Jiang, L; Meng, Y; Tong, T; Wang, K; Wang, L; Wu, J; Xu, X; You, X; Yu, Y; Zhang, W; Zhao, M1
Abe, R; Kawamura, N; Kawanishi, M; Murakami, M; Nagatsuji, M; Okajima, S; Suruga, M; Tokuyama, O; Yamane, T1
Kim, D; Kim, M; Kim, R; Kim, S; Kim, Y; Koh, Y; Ku, J; Kwon, NH; Lee, K; Lee, N; Song, S; Yoon, SS1
Iida, K; Ishibashi, T; Ishikawa, M; Katagiri, A; Katagiri, H; Miyazaki, K; Nakayama, K; Nakayama, N; Rahman, M; Rahman, MT1
Altmann, KH; Ambati, S; Calvo-Vidal, MN; Cerchietti, L; Díaz, JF; Fang, W; Jordi, M; Kahn, A; Moore, MAS; Pera, B1
Chen, YJ; Huang, HM; Huang, YW; Lee, YL; Liou, JP; Liu, HE; Wang, CC1
Asbell, SO; Bae, K; Kerlin, KJ; Michalski, JM; Pienta, KJ; Rajan, R; Rosenthal, SA; Sandler, HM; Sobczak, ML1
Irie, T; Mori, A; Morioka, M; Saito, M; Tanaka, M1
Foretová, L; Fridrichová, P; Laco, J; Melichar, B; Papajík, T; Simkovič, M1
Boehlke, I; Bokemeyer, C; Hartmann, JT; Kanz, L; Kollmannsberger, C; Kuczyk, M; Metzner, B; Schleicher, J; Schleucher, N; Wierecky, J1
Berry, DA; Budman, DR; Cirrincione, C; Citron, ML; Henderson, IC; Hudis, CA; Muss, HB; Norton, L; Winer, EP1
Han, K; Kim, HJ; Kim, M; Kim, SY; Kim, Y; Lee, SY; Lim, J; Park, IY1
Ahmed, T; Darzynkiewicz, Z; Feldman, EJ; Halicka, HD; Lederman, CA; Li, X; Romero, MB; Seiter, K; Traganos, F1
Bhalla, K; Bullock, G; Huang, Y; Ibrado, AM; Mahoney, ME; Ponnathpur, V; Ray, S; Tang, C1
Curtis, JE; McCulloch, EA; Minden, MD; Minkin, S1
Andreeff, M; Estey, EH; Kantarjian, H; Keating, M; Munker, R; O'Brien, S1
Hu, ZB; McCulloch, EA; Minden, MD1
Craig, RW; Eastman, A; Townsend, KJ; Traupman, MA; Trusty, JL1
Hu, ZB; McCulloch, EA; Minden, MD; Stahl, J1
Larsson, BS; Mårs, U; Masquelier, M; Pålsson, M; Peterson, CO; Vitols, S1
Fowler, JM; Greer, BE; Horowitz, IR; McGuire, WP; Rodriguez, M; Rose, PG; Waggoner, S1
Baker, JR; Donehower, RC; Gralla, RJ; Leyland-Jones, B; Ohnuma, T; Trump, DL; Van Echo, DA; Von Hoff, DD; Weiss, RB; Wiernik, PH1
Boitnott, JK; Donehower, RC; Hruban, RH; Yardley, JH1
Allison, DC; Donehower, RC; Roberts, JR; Robertson, J; Rowinsky, EK1
Donehower, RC; Jones, RJ; Rowinsky, EK; Tucker, RW1

Trials

5 trial(s) available for paclitaxel and Leukemia, Myeloid, Acute

ArticleYear
Phase III multi-institutional trial of adjuvant chemotherapy with paclitaxel, estramustine, and oral etoposide combined with long-term androgen suppression therapy and radiotherapy versus long-term androgen suppression plus radiotherapy alone for high-ris
    International journal of radiation oncology, biology, physics, 2009, Mar-01, Volume: 73, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Administration Schedule; Estramustine; Etoposide; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Paclitaxel; Prostatic Neoplasms; Thromboembolism

2009
Toxicity of older and younger patients treated with adjuvant chemotherapy for node-positive breast cancer: the Cancer and Leukemia Group B Experience.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Aug-20, Volume: 25, Issue:24

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Lymphatic Metastasis; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Paclitaxel

2007
Evaluation of in vivo induction of apoptosis in patients with acute leukemia treated on a phase I study of paclitaxel.
    Leukemia, 1995, Volume: 9, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Apoptosis; Blast Crisis; DNA Damage; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Paclitaxel; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1995
Phase I study of taxol in refractory acute myelogenous leukemias using a weekly schedule.
    Acta haematologica, 1998, Volume: 99, Issue:2

    Topics: Adult; Aged; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Middle Aged; Paclitaxel

1998
Phase I study of paclitaxel, carboplatin, and increasing days of prolonged oral etoposide in ovarian, peritoneal, and tubal carcinoma: a gynecologic oncology group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:16

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Etoposide; Fallopian Tube Neoplasms; Female; Humans; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Middle Aged; Neutropenia; Ovarian Neoplasms; Paclitaxel; Peritoneal Neoplasms; Thrombocytopenia

2000

Other Studies

25 other study(ies) available for paclitaxel and Leukemia, Myeloid, Acute

ArticleYear
Crystal Structures and Human Leukemia Cell Apoptosis Inducible Activities of Parthenolide Analogues Isolated from Piptocoma rufescens.
    Journal of natural products, 2018, 03-23, Volume: 81, Issue:3

    Topics: Apoptosis; Asteraceae; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia, Myeloid, Acute; NF-kappa B; Sesquiterpenes

2018
Risk of MDS/AML with the addition of neoadjuvant carboplatin to standard chemotherapy for triple-negative breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2022, Volume: 33, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Female; Humans; Leukemia, Myeloid, Acute; Neoadjuvant Therapy; Paclitaxel; Treatment Outcome; Triple Negative Breast Neoplasms

2022
Reply to the Letter to the Editor 'Risk of MDS/AML with the addition of neoadjuvant carboplatin to standard chemotherapy for triple-negative breast cancer' by A. Okines and N. Turner.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2022, Volume: 33, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Humans; Leukemia, Myeloid, Acute; Neoadjuvant Therapy; Paclitaxel; Triple Negative Breast Neoplasms

2022
Analgesic and preventive effects of donepezil in animal models of chemotherapy-induced peripheral neuropathy: Involvement of spinal muscarinic acetylcholine M2 receptors.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 149

    Topics: Acetylcholine; Analgesics; Animals; Antineoplastic Agents; Cholinesterase Inhibitors; Donepezil; Leukemia, Myeloid, Acute; Models, Animal; Paclitaxel; Peripheral Nervous System Diseases; Rats; Receptor, Muscarinic M2; Receptors, Muscarinic

2022
[Effects of Paclitaxel and Quizartinib Alone and in Combination on AML Cell Line MV4-11 and Its STAT5 Signal Pathway].
    Zhongguo shi yan xue ye xue za zhi, 2022, Volume: 30, Issue:3

    Topics: Apoptosis; Benzothiazoles; Cell Line, Tumor; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Paclitaxel; Phenylurea Compounds; RNA, Messenger; Signal Transduction; STAT5 Transcription Factor

2022
A Ferroptosis-Inducing and Leukemic Cell-Targeting Drug Nanocarrier Formed by Redox-Responsive Cysteine Polymer for Acute Myeloid Leukemia Therapy.
    ACS nano, 2023, 02-28, Volume: 17, Issue:4

    Topics: Animals; Cysteine; Ferroptosis; Leukemia, Myeloid, Acute; Mice; Oxidation-Reduction; Paclitaxel; Polymers

2023
[A Case of Myelodysplastic Syndrome Developed during Chemotherapy for Postoperative Recurrent Ovarian Cancer That Progressed to Acute Myeloid Leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2023, Volume: 50, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Carcinoma, Ovarian Epithelial; Female; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Ovarian Neoplasms; Paclitaxel; Quality of Life

2023
Single-cell analysis of AIMP2 splice variants informs on drug sensitivity and prognosis in hematologic cancer.
    Communications biology, 2020, 10-30, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alternative Splicing; Cell Line, Tumor; Drug Resistance, Neoplasm; Exons; Female; Gene Expression Regulation, Neoplastic; Hematologic Neoplasms; Humans; Image Processing, Computer-Assisted; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Male; Middle Aged; Molecular Targeted Therapy; Nuclear Proteins; Paclitaxel; Prognosis; Single-Cell Analysis; Young Adult

2020
Therapy-related myelodysplastic syndrome and acute myeloid leukemia following chemotherapy (paclitaxel and carboplatin) and radiation therapy in ovarian cancer: a case report.
    European journal of gynaecological oncology, 2014, Volume: 35, Issue:4

    Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Cerebral Infarction; Chemoradiotherapy; Fatal Outcome; Female; Humans; Leukemia, Myeloid, Acute; Liver Neoplasms; Myelodysplastic Syndromes; Neoplasms, Second Primary; Neoplastic Cells, Circulating; Ovarian Neoplasms; Paclitaxel

2014
High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells.
    Cancer letters, 2015, Nov-01, Volume: 368, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Hematopoietic Stem Cells; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Macrolides; Mice; Microtubules; Neoplastic Stem Cells; Paclitaxel; Time Factors; Tubulin Modulators

2015
MPT0B169, a novel tubulin inhibitor, induces apoptosis in taxol-resistant acute myeloid leukemia cells through mitochondrial dysfunction and Mcl-1 downregulation.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:5

    Topics: Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Membrane Potential, Mitochondrial; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Paclitaxel; Sarcosine; Sulfonamides; Tubulin Modulators

2016
[Therapy-related acute myeloid leukemia with 11q23 abnormality due to paclitaxel coexisting with bone marrow metastasis of breast cancer].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Bone Marrow Neoplasms; Breast Neoplasms; Chromosome Aberrations; Chromosomes, Human, Pair 11; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasms, Second Primary; Paclitaxel

2009
Therapy-related myeloid neoplasms in epithelial ovarian cancer patients carrying BRCA1 mutation: report of two cases.
    Acta oncologica (Stockholm, Sweden), 2012, Volume: 51, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ovarian Epithelial; Cystadenocarcinoma, Serous; Fatal Outcome; Female; Genes, BRCA1; Heterozygote; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Neoplasms, Glandular and Epithelial; Neoplasms, Second Primary; Ovarian Neoplasms; Paclitaxel; Platinum

2012
Secondary leukemia after first-line high-dose chemotherapy for patients with advanced germ cell cancer.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase II as Topic; Etoposide; Follow-Up Studies; Germany; Germinoma; Humans; Ifosfamide; Leukemia, Myeloid, Acute; Male; Mediastinal Neoplasms; Multicenter Studies as Topic; Myelodysplastic Syndromes; Neoplasms, Second Primary; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Testicular Neoplasms; Translocation, Genetic; Transplantation, Autologous

2005
[A case of therapy-related acute myeloid leukemia associated with inv(16)].
    The Korean journal of laboratory medicine, 2007, Volume: 27, Issue:1

    Topics: Antimitotic Agents; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 16; Cisplatin; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Paclitaxel; Taxoids

2007
1-beta-D-arabinofuranosylcytosine-, mitoxantrone-, and paclitaxel-induced apoptosis in HL-60 cells: improved method for detection of internucleosomal DNA fragmentation.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cytarabine; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrophoresis, Agar Gel; Genome, Human; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Paclitaxel; Tumor Cells, Cultured

1994
A role for paclitaxel in the combination chemotherapy of acute myeloblastic leukaemia: preclinical cell culture studies.
    British journal of haematology, 1996, Volume: 95, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Paclitaxel; Tretinoin; Tumor Cells, Cultured

1996
Phosphorylation of BCL-2 after exposure of human leukemic cells to retinoic acid.
    Blood, 1998, Sep-01, Volume: 92, Issue:5

    Topics: Dimerization; Electrophoresis, Gel, Two-Dimensional; Humans; Immunosorbent Techniques; Leukemia, Myeloid, Acute; Paclitaxel; Phosphoamino Acids; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Tretinoin; Tumor Cells, Cultured

1998
Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C.
    Oncogene, 1998, Sep-10, Volume: 17, Issue:10

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cisplatin; Colchicine; Humans; Leukemia, Myeloid, Acute; Microtubules; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Paclitaxel; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vinblastine

1998
Regulation of drug sensitivity by ribosomal protein S3a.
    Blood, 2000, Feb-01, Volume: 95, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line; Cryopreservation; Cytarabine; DNA Replication; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Gene Targeting; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Neoplasm Proteins; Neoplastic Stem Cells; Paclitaxel; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Rats; Ribosomal Proteins; Tissue Preservation; Treatment Outcome; Tretinoin

2000
Low density lipoprotein as a carrier of cytostatics in cancer chemotherapy: study of stability of drug-carrier complexes in blood.
    Journal of drug targeting, 2000, Volume: 8, Issue:3

    Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Doxorubicin; Drug Carriers; Female; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lipoproteins, LDL; Male; Mice; Mice, Inbred BALB C; Middle Aged; Paclitaxel

2000
Hypersensitivity reactions from taxol.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:7

    Topics: Adult; Aged; Alkaloids; Antineoplastic Agents, Phytogenic; Cimetidine; Colonic Neoplasms; Dexamethasone; Drug Administration Schedule; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Immediate; Leukemia, Myeloid, Acute; Male; Melanoma; Middle Aged; Paclitaxel; Premedication

1990
Taxol toxicity. Epithelial necrosis in the gastrointestinal tract associated with polymerized microtubule accumulation and mitotic arrest.
    Cancer, 1989, May-15, Volume: 63, Issue:10

    Topics: Adult; Aged; Alkaloids; Antineoplastic Agents, Phytogenic; Digestive System; Epithelium; Female; Germ Cells; Humans; Leukemia, Myeloid, Acute; Male; Microtubules; Middle Aged; Mitosis; Necrosis; Ovarian Neoplasms; Paclitaxel; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Testis

1989
Demonstration of the cell cycle positions of taxol-induced "asters" and "bundles" by sequential measurements of tubulin immunofluorescence, DNA content, and autoradiographic labeling of taxol-sensitive and -resistant cells.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1989, Volume: 37, Issue:11

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Autoradiography; Cell Cycle; Cell Line; DNA; Drug Resistance; Fluorescent Antibody Technique; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Microtubules; Mitosis; Paclitaxel; Thymidine; Tubulin

1989
Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol.
    Cancer research, 1988, Jul-15, Volume: 48, Issue:14

    Topics: Alkaloids; Cell Line; Cell Survival; Flow Cytometry; Fluorescent Antibody Technique; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Microscopy, Electron; Microtubules; Paclitaxel

1988