Compounds > paclitaxel
Page last updated: 2024-08-23

paclitaxel and Leucocythaemia

paclitaxel has been researched along with Leucocythaemia in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.85)18.7374
1990's16 (29.63)18.2507
2000's20 (37.04)29.6817
2010's14 (25.93)24.3611
2020's3 (5.56)2.80

Authors

AuthorsStudies
Christ, WJ; Habgood, GJ; Kishi, Y; Littlefield, BA; Wang, Y; Yu, MJ1
Hanumappa, A; Hegde, M; Narasimhamurthy, KH; Raghavan, SC; Rangappa, KS; Sharath Kumar, KS1
Casciano, F; Marchesi, E; Melloni, E; Navacchia, ML; Perrone, D; Preti, L; Rimondi, E; Romani, A; Secchiero, P1
Drogosz-Stachowicz, J; Długosz-Pokorska, A; Gach-Janczak, K; Jakubowski, R; Janecka, A; Janecki, T; Szymański, J1
Fujiwara, H; Fujiwara, K; Kanuma, T; Nakamura, K; Nakamura, Y; Sakurai, M; Satoh, T; Suzuki, M; Takahashi, S; Takei, Y1
Calviño, E; Diez, JC; Herráez, A; Morales-Cano, D; Rubio, V; Sancho, P; Tejedor, MC1
Fu, CY; Lu, Y; Xia, RL; Zhang, SF; Zhao, FK; Zhu, LN1
Bertomeu, T; Bucur, O; Dewar, R; Goganau, I; Khosravi-Far, R; Pennarun, B; Petrescu, SM; Stancu, AL1
Ding, N; Feng, L; Ping, L; Shi, Y; Song, Y; Zheng, X; Zhu, J1
Christen, TD; Fondy, TP; Gadeberg, L; Sansky, M; Trendowski, M; Wong, V; Zoino, JN1
Jia, Z; Liu, L; Qi, MY; Shan, ZM; Wen, J; Wu, SZ; Xiu, HH; Xu, KQ; Zhang, T1
Feng, XL; Huang, X; Liu, DC; Peng, ZG; Tang, YL; Wang, XX; Yang, J; Yao, YB1
Bui, T; Ho, RJ; Wu, D; Yang, Z1
Abe, A; Ikawa, H; Maeda, Y; Muguruma, H1
Meshkini, A; Yazdanparast, R1
Aggarwal, BB; Chaturvedi, MM; Park, B; Sung, B; Yadav, VR1
Dilnawaz, F; Sahoo, SK; Singh, A1
Jia, L; Jiang, L; Miao, X; Zhang, Z; Zhao, Y; Zhou, H1
Ishikawa, M; Kanno, S; Katoh, T; Maeda, N; Tomizawa, A; Yomogida, S1
Alessandri, G; Benetti, A; Bonomi, A; Caruso, A; Cavicchini, L; Ceccarelli, P; Ciusani, E; Coccè, V; Crovace, A; Falchetti, ML; Ferrari, M; Marfia, G; Navone, S; Parati, E; Pascucci, L; Pessina, A; Sisto, F; Zicari, S1
Banai, Y; Gokulan, K; Khare, S; Linthicum, DS; Modiano, JF; Smith, R1
Arima, T; Hanada, S; Lin, XY; Ohno, N; Owatari, S; Suzuki, S; Takatsuka, Y; Takeshita, T; Takeuchi, S; Uozumi, K1
Igarashi, M; Ikeda, Y; Kinoshita, N; Miyake, K; Ohno, O; Sawa, R; Suzuki, Y; Umezawa, K1
Ahmed, W; Dent, P; Grant, S; Rahmani, M1
Arsenau, D; Budnikova, M; Dhar, S; Hassan, S; Karlsson, MO; Larsson, R; Lindhagen, E; Lobanov, N; Lokot, I; Sandström, M1
Chung, JG; Liao, HH; Lin, KL; Lu, KH; Lue, KH1
Assreuy, J; Freitas, MS; Santos-Silva, MC1
Assreuy, J; Lima, JH; Lunardi, F1
Jing, Y; Waxman, S; Wurmbach, E; Xia, L1
Bodo, J; Duraj, J; Rauko, P; Sedlak, J; Sulikova, M1
Kogo, Y; Ohishi, I; Uematsu, Y1
Ames, MM; Horton, TM; Krailo, MD; Mosher, R; Pendergrass, T; Reaman, GH; Reid, JM; Seibel, NL1
Lei, P; Li, W; Shao, J; Shen, G; Wang, X; Yang, J; Ye, Q; Zhang, Y; Zhu, H1
Hsu, PC; Hung, HC; Liao, YF; Liu, CC; Liu, GY; Tsay, GJ1
Fabbi, M; Gangemi, RM; Marchetti, C; Severi, AB; Tiso, M1
Erusalimsky, JD; Hancock, V; Hong, Y; Martin, JF; van der Loo, B1
Choy, H; Hilsenbeck, S; Koester, S; Rodriguez, FF; Von Hoff, DD1
Baguley, BC; Finlay, GJ1
Aronadio, O; Costa, G; d'Aquino, S; Fulco, RA; Gangemi, RM1
Faure, P; Madelaine-Chambrin, I; Piquet-Sevrin, V1
Markman, M1
Hirose, Y; Takiguchi, T1
Basu, A; Croce, CM; Haldar, S1
Baguley, BC; Davey, MW; Davey, RA; Hargrave, RM; Harvie, RM; Su, GM1
Bombardelli, E; De Vincenzo, R; Distefano, M; Fattorossi, A; Ferlini, C; Gaggini, C; Mancuso, S; Ojima, I; Panici, PB; Riva, A; Scambia, G1
Al-alami, O; Hassan, HT; Martin, JH; Sammons, J1
Canada, AL; Ross, HJ; Slater, LM1
Evans, WE; Pappo, AS; Pratt, CB; Pui, CH; Relling, MV; Rivera, GK; Sonnichsen, DS; Woo, MH1
Blagosklonny, MV1
Larsson, BS; Mårs, U; Masquelier, M; Pålsson, M; Peterson, CO; Vitols, S1
Bhalla, KN; Blagosklonny, MV; Figg, WD; Fojo, T; Kim, JS; Neckers, LM; Rivera, Y; Trepel, JB1
Chou, MC; Chung, JG; Ho, HC; Hsia, TC; Hsiao, YM; Lin, KL; Lu, KH; Yang, CC1
Allison, DC; Donehower, RC; Roberts, JR; Rowinsky, EK1
Burke, PJ; Donehower, RC; Ettinger, DS; Karp, JE; Rowinsky, EK; Tucker, RW1

Reviews

1 review(s) available for paclitaxel and Leucocythaemia

ArticleYear
[Current therapeutic methods in onco-hematology].
    Annales pharmaceutiques francaises, 1996, Volume: 54, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cladribine; Docetaxel; Humans; Keratolytic Agents; Leukemia; Paclitaxel; Taxoids; Topoisomerase I Inhibitors; Tretinoin; Vidarabine

1996

Trials

2 trial(s) available for paclitaxel and Leucocythaemia

ArticleYear
A Phase 1 and pharmacokinetic clinical trial of paclitaxel for the treatment of refractory leukemia in children: a Children's Oncology Group study.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Infant; Infant, Newborn; Leukemia; Male; Maximum Tolerated Dose; Metabolic Clearance Rate; Neoplasm Recurrence, Local; Paclitaxel; Treatment Outcome

2008
Phase I targeted systemic exposure study of paclitaxel in children with refractory acute leukemias.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:3

    Topics: Acute Disease; Adolescent; Antineoplastic Agents, Phytogenic; Child; Female; Humans; Leukemia; Male; Outcome Assessment, Health Care; Paclitaxel

1999

Other Studies

51 other study(ies) available for paclitaxel and Leucocythaemia

ArticleYear
Structure-activity relationships of halichondrin B analogues: modifications at C.30-C.38.
    Bioorganic & medicinal chemistry letters, 2000, May-15, Volume: 10, Issue:10

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Ethers, Cyclic; Humans; Leukemia; Macrolides; Mice; Structure-Activity Relationship; Tumor Cells, Cultured

2000
Synthesis and antiproliferative effect of novel 4-thiazolidinone-, pyridine- and piperazine-based conjugates on human leukemic cells.
    European journal of medicinal chemistry, 2014, Jun-23, Volume: 81

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Humans; K562 Cells; Leukemia; Membrane Potential, Mitochondrial; Molecular Structure; Piperazine; Piperazines; Pyridines; Structure-Activity Relationship; Thiazolidines; Tumor Cells, Cultured

2014
Synthesis and Biological Investigation of Bile Acid-Paclitaxel Hybrids.
    Molecules (Basel, Switzerland), 2022, Jan-12, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Bile Acids and Salts; Cell Line; Cell Survival; Colonic Neoplasms; Deoxycholic Acid; Humans; Leukemia; Mice; Paclitaxel

2022
A New Hybrid δ-Lactone Induces Apoptosis and Potentiates Anticancer Activity of Taxol in HL-60 Human Leukemia Cells.
    Molecules (Basel, Switzerland), 2020, Mar-25, Volume: 25, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Proliferation; Drug Synergism; Enzyme Activation; fas Receptor; HL-60 Cells; Human Umbilical Vein Endothelial Cells; Humans; Lactones; Leukemia; Paclitaxel; Signal Transduction

2020
Treatment-related leukemia after taxane and platinum therapy in gynecological cancer patients (Gynecologic Oncology Trial and Investigation Consortium 011).
    The journal of obstetrics and gynaecology research, 2021, Volume: 47, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Female; Genital Neoplasms, Female; Humans; Leukemia; Ovarian Neoplasms; Paclitaxel; Platinum; Retrospective Studies; Taxoids

2021
Apoptosis induced by paclitaxel via Bcl-2, Bax and caspases 3 and 9 activation in NB4 human leukaemia cells is not modulated by ERK inhibition.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2013, Volume: 65, Issue:7-8

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Humans; Leukemia; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Signal Transduction

2013
Different regulatory pathways are involved in the proliferative inhibition of two types of leukemia cell lines induced by paclitaxel.
    Oncology reports, 2013, Volume: 30, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia; M Phase Cell Cycle Checkpoints; Paclitaxel

2013
Combination of bortezomib and mitotic inhibitors down-modulate Bcr-Abl and efficiently eliminates tyrosine-kinase inhibitor sensitive and resistant Bcr-Abl-positive leukemic cells.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Benzamides; Boronic Acids; Bortezomib; Caspases; Cell Death; Cell Line, Tumor; Dasatinib; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Fusion Proteins, bcr-abl; Heterocyclic Compounds, 2-Ring; Humans; Imatinib Mesylate; JNK Mitogen-Activated Protein Kinases; Leukemia; Mitosis; Models, Biological; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Pteridines; Pyrazines; Pyrimidines; Signal Transduction; STAT5 Transcription Factor; Thiazoles

2013
Thiamet-G-mediated inhibition of O-GlcNAcase sensitizes human leukemia cells to microtubule-stabilizing agent paclitaxel.
    Biochemical and biophysical research communications, 2014, Oct-24, Volume: 453, Issue:3

    Topics: beta-N-Acetylhexosaminidases; Humans; Jurkat Cells; Leukemia; Microtubules; Paclitaxel; Phosphorylation; Pyrans; tau Proteins; Thiazoles

2014
Preferential enlargement of leukemia cells using cytoskeletal-directed agents and cell cycle growth control parameters to induce sensitivity to low frequency ultrasound.
    Cancer letters, 2015, May-01, Volume: 360, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Death; Cell Growth Processes; Culture Media, Serum-Free; Cytochalasin B; Cytoskeleton; Depsipeptides; Humans; Leukemia; Leukemia L1210; Mice; Microtubules; Paclitaxel; U937 Cells; Ultrasonic Therapy; Ultrasonography; Vincristine

2015
Butorphanol, a synthetic opioid, sensitizes ABCB1-mediated multidrug resistance via inhibition of the efflux function of ABCB1 in leukemia cells.
    Oncology reports, 2015, Volume: 34, Issue:2

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Butorphanol; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Leukemia; Neoplasm Proteins; Paclitaxel

2015
Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway.
    Genetics and molecular research : GMR, 2016, Mar-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation, Leukemic; Humans; Jurkat Cells; Leukemia; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Paclitaxel

2016
A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transport.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:2

    Topics: Acridines; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Doxorubicin; Drug Resistance, Neoplasm; Genotype; Haplotypes; Humans; Leukemia; Middle Aged; Paclitaxel; Polymorphism, Single Nucleotide; Tetrahydroisoquinolines; Vinblastine

2008
[Secondary myelodysplasia and leukemia following carboplatin and paclitaxel-containing chemotherapy for ovarian cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Female; Humans; Leukemia; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Ovarian Neoplasms; Paclitaxel; Treatment Failure

2008
Chemosensitization of human leukemia K562 cells to taxol by a Vanadium-salen complex.
    Experimental and molecular pathology, 2010, Volume: 89, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Proliferation; Cell Separation; Ethylenediamines; Flow Cytometry; Fluorescent Antibody Technique; Humans; K562 Cells; Leukemia; Paclitaxel; Vanadium Compounds

2010
Triptolide, histone acetyltransferase inhibitor, suppresses growth and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK pathway.
    Biochemical pharmacology, 2011, Nov-01, Volume: 82, Issue:9

    Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Diterpenes; Enzyme Inhibitors; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Inflammation; Leukemia; Molecular Structure; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Paclitaxel; Phenanthrenes; Signal Transduction; Thalidomide; Tumor Necrosis Factor-alpha

2011
Long circulating lectin conjugated paclitaxel loaded magnetic nanoparticles: a new theranostic avenue for leukemia therapy.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Chemical Phenomena; Chemistry, Pharmaceutical; Endocytosis; Fusion Proteins, bcr-abl; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Jurkat Cells; K562 Cells; Lectins; Leukemia; M Phase Cell Cycle Checkpoints; Magnetite Nanoparticles; Male; Membrane Potential, Mitochondrial; Molecular Imaging; Paclitaxel; Rats

2011
Glycomic alterations are associated with multidrug resistance in human leukemia.
    The international journal of biochemistry & cell biology, 2012, Volume: 44, Issue:8

    Topics: Antineoplastic Agents; Blotting, Western; Cell Survival; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescein-5-isothiocyanate; Gene Expression Regulation, Neoplastic; Glycomics; Humans; K562 Cells; Lectins; Leukemia; N-Acetylglucosaminyltransferases; Paclitaxel; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Polysaccharides; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sialyltransferases; Tunicamycin; Vincristine

2012
Characterization of cells resistant to the potent histone deacetylase inhibitor spiruchostatin B (SP-B) and effect of overexpressed p21waf1/cip1 on the SP-B resistance or susceptibility of human leukemia cells.
    International journal of oncology, 2012, Volume: 41, Issue:3

    Topics: Apoptosis; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Depsipeptides; Doxorubicin; Drug Resistance, Neoplasm; Gene Transfer Techniques; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leukemia; Paclitaxel; RNA, Messenger; Vincristine

2012
Mesenchymal stromal cells primed with Paclitaxel attract and kill leukaemia cells, inhibit angiogenesis and improve survival of leukaemia-bearing mice.
    British journal of haematology, 2013, Volume: 160, Issue:6

    Topics: Animals; Cell Communication; Cell Growth Processes; Cell Line, Tumor; Disease Models, Animal; Humans; Leukemia; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Nude; Neovascularization, Pathologic; Paclitaxel; Xenograft Model Antitumor Assays

2013
Early changes in metabolism of leukemic cell lines upon induction of apoptosis by cytotoxic drugs.
    European journal of pharmacology, 2003, Mar-28, Volume: 465, Issue:1-2

    Topics: Amiloride; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; K562 Cells; Leukemia; Paclitaxel; Sodium Azide; U937 Cells

2003
A novel c-kit positive biphenotypic acute leukemia cell line, TMBL-1, carrying a p53 point mutation.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:5

    Topics: Adult; Bone Marrow Cells; Cell Division; Humans; Immunophenotyping; Leukemia; Male; Myeloid Cells; Paclitaxel; Point Mutation; Proto-Oncogene Proteins c-kit; Stem Cell Factor; T-Lymphocytes; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2003
Isolation of heptadepsin, a novel bacterial cyclic depsipeptide that inhibits lipopolysaccharide activity.
    Chemistry & biology, 2004, Volume: 11, Issue:8

    Topics: Animals; Cell Adhesion; Cell Proliferation; Cells, Cultured; Depsipeptides; Epithelial Cells; Gene Expression Regulation; Humans; Leukemia; Ligands; Lipopolysaccharide Receptors; Lipopolysaccharides; Mice; Molecular Structure; NF-kappa B; Paclitaxel; Receptors, Cell Surface; Signal Transduction; Toll-Like Receptor 4

2004
The cyclin-dependent kinase inhibitor p21(CIP1/WAF1) blocks paclitaxel-induced G2M arrest and attenuates mitochondrial injury and apoptosis in p53-null human leukemia cells.
    Cell cycle (Georgetown, Tex.), 2004, Volume: 3, Issue:10

    Topics: Antisense Elements (Genetics); Apoptosis; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Doxycycline; Flow Cytometry; G2 Phase; Humans; Jurkat Cells; Leukemia; Membrane Potentials; Mitochondria; Mitotic Index; Paclitaxel; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; U937 Cells

2004
Cytotoxic activity of a new paclitaxel formulation, Pacliex, in vitro and in vivo.
    Cancer chemotherapy and pharmacology, 2005, Volume: 55, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Humans; Leukemia; Micelles; Multiple Myeloma; Paclitaxel; Tumor Cells, Cultured

2005
Induction of caspase-3-dependent apoptosis in human leukemia HL-60 cells by paclitaxel.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Jul-01, Volume: 357, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Division; Dose-Response Relationship, Drug; Flow Cytometry; HL-60 Cells; Humans; Leukemia; Paclitaxel; Protease Inhibitors

2005
Involvement of NF-kappaB and glutathione in cytotoxic effects of nitric oxide and taxol on human leukemia cells.
    Leukemia research, 2006, Volume: 30, Issue:2

    Topics: Buthionine Sulfoximine; Carmustine; Cell Line, Tumor; Glutathione; Humans; Leukemia; NF-kappa B; Nitric Oxide; Paclitaxel; Proline; S-Nitroso-N-Acetylpenicillamine; Thiocarbamates

2006
Comparative study of respiratory burst induced by phorbol ester and zymosan in human granulocytes.
    Clinical biochemistry, 2006, Volume: 39, Issue:1

    Topics: Adult; Calcium; Cells, Cultured; Colchicine; Cytochalasin D; Cytoskeleton; Erythrocytes; Female; Flow Cytometry; Granulocytes; Humans; Leukemia; Leukocytes; Male; Middle Aged; Paclitaxel; Phorbol Esters; Protein Kinase C; Respiratory Burst; Signal Transduction; Zymosan

2006
Upregulation of Bfl-1/A1 in leukemia cells undergoing differentiation by all-trans retinoic acid treatment attenuates chemotherapeutic agent-induced apoptosis.
    Leukemia, 2006, Volume: 20, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Gene Silencing; HL-60 Cells; Humans; Leukemia; Minor Histocompatibility Antigens; Oxides; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Tretinoin; Up-Regulation

2006
Diverse resveratrol sensitization to apoptosis induced by anticancer drugs in sensitive and resistant leukemia cells.
    Neoplasma, 2006, Volume: 53, Issue:5

    Topics: Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Busulfan; Cell Cycle; Cell Line, Tumor; Cycloheximide; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gemcitabine; Humans; Leukemia; Paclitaxel; Resveratrol; Stilbenes

2006
Disassembly of actin filaments by botulinum C2 toxin and actin-filament-disrupting agents induces assembly of microtubules in human leukaemia cell lines.
    Biology of the cell, 2007, Volume: 99, Issue:3

    Topics: Actin Cytoskeleton; Actins; Antineoplastic Agents; Botulinum Toxins; Cell Line, Tumor; Cell Polarity; HL-60 Cells; Humans; Leukemia; Microtubules; Nocodazole; Paclitaxel; Tubulin Modulators

2007
Antisense RNA of survivin gene inhibits the proliferation of leukemia cells and sensitizes leukemia cell line to taxol-induced apoptosis.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2008, Volume: 28, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Flow Cytometry; HL-60 Cells; Humans; Inhibitor of Apoptosis Proteins; Inhibitory Concentration 50; Leukemia; Microtubule-Associated Proteins; Neoplasm Proteins; Paclitaxel; RNA, Antisense; Survivin; Tetrazolium Salts; Thiazoles

2008
Ornithine decarboxylase attenuates leukemic chemotherapy drugs-induced cell apoptosis and arrest in human promyelocytic HL-60 cells.
    Leukemia research, 2008, Volume: 32, Issue:10

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cisplatin; Etoposide; Glutathione; HL-60 Cells; Humans; Leukemia; Membrane Potential, Mitochondrial; Ornithine Decarboxylase; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Putrescine; Reactive Oxygen Species

2008
Taxol cytotoxicity on human leukemia cell lines is a function of their susceptibility to programmed cell death.
    Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:5

    Topics: Apoptosis; Cycloheximide; Drug Resistance; Electrophoresis, Agar Gel; Flow Cytometry; Humans; Leukemia; Microscopy, Electron; Paclitaxel; Thymidine; Time Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay

1995
Antimicrotubule agents induce polyploidization of human leukaemic cell lines with megakaryocytic features.
    European journal of clinical investigation, 1993, Volume: 23, Issue:10

    Topics: Cell Division; Colchicine; Demecolcine; DNA; Flow Cytometry; Humans; Leukemia; Lumicolchicines; Megakaryocytes; Microtubules; Nocodazole; Paclitaxel; Polyploidy; Tumor Cells, Cultured

1993
Investigation of taxol as a potential radiation sensitizer.
    Cancer, 1993, Jun-01, Volume: 71, Issue:11

    Topics: Cell Survival; Dose-Response Relationship, Drug; G2 Phase; Humans; Leukemia; Paclitaxel; Radiation-Sensitizing Agents; Tumor Cells, Cultured

1993
Pharmacokinetic/cytokinetic principles in the chemotherapy of solid tumours.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:11

    Topics: Acridines; Antineoplastic Agents; Camptothecin; Cell Cycle; Drug Design; Drug Screening Assays, Antitumor; Humans; Leukemia; Paclitaxel; Tumor Cells, Cultured

1995
Apoptosis susceptibility of human carcinoma and leukemia cell lines to taxol. Relationship with cell cycle and drug concentration.
    Annals of the New York Academy of Sciences, 1996, Apr-30, Volume: 784

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Cycle; Female; Flow Cytometry; Humans; Kinetics; Leukemia; Paclitaxel; Tumor Cells, Cultured

1996
Eighty-seventh annual meeting of the American Association for Cancer Research. Washington, D,C., 20-24 April 1996.
    Journal of cancer research and clinical oncology, 1996, Volume: 122, Issue:9

    Topics: Aged; Antineoplastic Agents; Breast; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Female; Genes, p53; Genes, Tumor Suppressor; Humans; Hyperplasia; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Pancreatic Neoplasms; Research; Survival Rate

1996
Microtubule changes in hematologic malignant cells treated with paclitaxel and comparison with vincristine cytotoxicity.
    Blood cells, molecules & diseases, 1995, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Female; Fluorescent Antibody Technique, Indirect; Humans; Leukemia; Lymphoma; Male; Microtubules; Middle Aged; Paclitaxel; Tubulin; Tumor Cells, Cultured; Vincristine

1995
Bcl2 is the guardian of microtubule integrity.
    Cancer research, 1997, Jan-15, Volume: 57, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Chronic Disease; Docetaxel; G2 Phase; Humans; Leukemia; Lymphoma, B-Cell; Male; Microtubules; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Taxoids; Tumor Cells, Cultured

1997
The potential of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide to circumvent three multidrug-resistance phenotypes in vitro.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:5

    Topics: Acridines; Amsacrine; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Line; Cell Survival; Daunorubicin; Drug Resistance, Multiple; HL-60 Cells; Humans; Idarubicin; Leukemia; Paclitaxel; Phenotype; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Verapamil

1997
Anti-proliferative activity of a new class of taxanes (14beta-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells.
    International journal of cancer, 1997, Sep-04, Volume: 72, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Humans; Leukemia; Mitosis; Paclitaxel; Structure-Activity Relationship; Taxoids; Triterpenes; Tumor Cells, Cultured

1997
Divergent effect of taxol on proliferation, apoptosis and nitric oxide production in MHH225 CD34 positive and U937 CD34 negative human leukaemia cells.
    Leukemia research, 1998, Volume: 22, Issue:10

    Topics: Acute Disease; Antigens, CD34; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; Humans; Leukemia; Leukemia, Myeloid; Nitric Oxide; Paclitaxel; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured

1998
Cyclosporin A enhances paclitaxel toxicity against leukemia and respiratory epithelial cancers.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclosporine; Cytokines; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Glycerol; Growth Substances; Humans; Immunosuppressive Agents; Leukemia; Mice; Paclitaxel; Respiratory Tract Neoplasms; Survival Rate; Treatment Outcome; Tumor Cells, Cultured

1997
Drug-resistance enables selective killing of resistant leukemia cells: exploiting of drug resistance instead of reversal.
    Leukemia, 1999, Volume: 13, Issue:12

    Topics: Apoptosis; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia; Paclitaxel

1999
Low density lipoprotein as a carrier of cytostatics in cancer chemotherapy: study of stability of drug-carrier complexes in blood.
    Journal of drug targeting, 2000, Volume: 8, Issue:3

    Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Doxorubicin; Drug Carriers; Female; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lipoproteins, LDL; Male; Mice; Mice, Inbred BALB C; Middle Aged; Paclitaxel

2000
The Hsp90 inhibitor geldanamycin selectively sensitizes Bcr-Abl-expressing leukemia cells to cytotoxic chemotherapy.
    Leukemia, 2001, Volume: 15, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Doxorubicin; Drug Interactions; Drug Resistance; Fusion Proteins, bcr-abl; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leukemia; Paclitaxel; Quinones; Transfection; Tumor Cells, Cultured

2001
The effect of paclitaxel on gene expression and activity of arylamine N-acetyltransferase and DNA-2-aminofluorene adduct formation in human leukemia HL-60 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:5

    Topics: Acetylation; Animals; Antineoplastic Agents, Phytogenic; Arylamine N-Acetyltransferase; Carcinogens; Cytosol; Depression, Chemical; DNA Adducts; Dose-Response Relationship, Drug; Fluorenes; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Kinetics; Leukemia; Mice; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction

2002
Development of polyploidization in taxol-resistant human leukemia cells in vitro.
    Cancer research, 1990, Feb-01, Volume: 50, Issue:3

    Topics: Alkaloids; Cell Cycle; DNA, Neoplasm; Drug Resistance; Humans; Interphase; Leukemia; Paclitaxel; Polyploidy; Spindle Apparatus; Time Factors; Tumor Cells, Cultured

1990
Phase I and pharmacodynamic study of taxol in refractory acute leukemias.
    Cancer research, 1989, Aug-15, Volume: 49, Issue:16

    Topics: Acute Disease; Adult; Aged; Alkaloids; Antineoplastic Agents, Phytogenic; Bone Marrow; Drug Administration Schedule; Drug Evaluation; Female; Fluorescent Antibody Technique; Humans; Leukemia; Male; Microtubules; Middle Aged; Mouth Mucosa; Paclitaxel; Peripheral Nervous System Diseases; Stomatitis

1989