paclitaxel and Genome Instability
paclitaxel has been researched along with Genome Instability in 15 studies
Research
Studies (15)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (26.67) | 29.6817 |
2010's | 8 (53.33) | 24.3611 |
2020's | 3 (20.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Huang, YQ; Li, PP; Li, RG; Lu, JP; Wang, ZY; Zhang, WJ | 1 |
Aghajanian, C; Ansell, PJ; Birrer, MJ; Bookman, MA; Coleman, RL; Dinh, MH; Fleming, GF; Friedlander, M; Kaufmann, SH; Levine, DA; Moore, KN; O'Malley, DM; Okamoto, A; Reid, TJ; Sehgal, V; Shahin, MS; Spirtos, NM; Steffensen, KD; Swisher, EM | 1 |
Churin, AA; Fedorova, EP; Filonova, MV; Neupokoeva, OV; Sandrikina, LA; Stavrova, LA; Voronova, OL | 1 |
Bass, TE; Cortez, D | 1 |
Kreis, NN; Louwen, F; Yuan, J | 1 |
Aittokallio, T; Brück, O; Edgren, H; Eldfors, S; Hultsch, S; Jaiswal, A; Kallioniemi, O; Kangaspeska, S; Mpindi, JP | 1 |
Bae, DS; Cho, WC; Cho, YJ; Choi, CH; Choi, JJ; Choi, YL; Heo, EJ; Hong, JE; Jeon, HK; Kim, BG; Kim, TJ; Lee, JW; Lee, YY; Oh, DY; Park, WY; Song, SY | 1 |
Button, B; Chu, D; Cidado, J; Cochran, RL; Cravero, K; Croessmann, S; Dalton, WB; Erlanger, B; Hurley, PJ; Kyker-Snowman, K; Lauring, J; Park, BH; Rosen, DM; Wong, HY; Zabransky, DJ | 1 |
Bhat, A; Feng, Z; Gupta, A; Hunt, CR; Jeffery, J; Kaul, SC; Khanna, KK; Kumar, R; Misri, S; Pagan, J; Pandita, RK; Pandita, TK; Parsons, R; Powell, SN; Puc, J; Wadhwa, R; Xiang, T; Yaguchi, T; Yang, Q; Zeng, S | 1 |
Li, Y; Liu, S; Lu, C; Shen, Y; Wang, M; Xu, R | 1 |
Bellot, GL; Koh, D; Tan, WH; Tay, LL; Wang, X | 1 |
Guan, H; Huang, B; Li, B; Liu, XD; Rang, WQ; Shang, ZF; Tu, WZ; Wang, Y; Yu, L; Zhou, PK | 1 |
Hagan, CR; Rudin, CM | 1 |
Chen, J; Draviam, VM; Elledge, SJ; Hannon, GJ; Harper, JW; Liang, A; Nalepa, G; Sorger, PK; Sowa, ME; Stegmeier, F | 1 |
Dixit, A; Kitagawa, K; Niikura, Y; Perkins, G; Scott, R | 1 |
Reviews
1 review(s) available for paclitaxel and Genome Instability
Article | Year |
---|---|
Less understood issues: p21(Cip1) in mitosis and its therapeutic potential.
Topics: CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Survival; Chromosome Segregation; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cytokinesis; Genomic Instability; Humans; Microtubule-Associated Proteins; Mitosis; Paclitaxel; Phosphorylation; Tubulin Modulators; Tumor Suppressor Protein p53 | 2015 |
Trials
1 trial(s) available for paclitaxel and Genome Instability
Article | Year |
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Impact of homologous recombination status and responses with veliparib combined with first-line chemotherapy in ovarian cancer in the Phase 3 VELIA/GOG-3005 study.
Topics: Adult; Aged; Aged, 80 and over; Allelic Imbalance; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; CA-125 Antigen; Carboplatin; Carcinoma, Ovarian Epithelial; Cytoreduction Surgical Procedures; Female; Genes, BRCA1; Genes, BRCA2; Genomic Instability; Hereditary Breast and Ovarian Cancer Syndrome; Humans; Induction Chemotherapy; Loss of Heterozygosity; Maintenance Chemotherapy; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Paclitaxel; Poly(ADP-ribose) Polymerase Inhibitors; Progression-Free Survival; Proportional Hazards Models; Recombinational DNA Repair; Young Adult | 2022 |
Other Studies
13 other study(ies) available for paclitaxel and Genome Instability
Article | Year |
---|---|
LncRNA OTUD6B-AS1 promotes paclitaxel resistance in triple negative breast cancer by regulation of miR-26a-5p/MTDH pathway-mediated autophagy and genomic instability.
Topics: Animals; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Genomic Instability; Humans; Membrane Proteins; Mice, Nude; MicroRNAs; Paclitaxel; RNA-Binding Proteins; RNA, Long Noncoding; Triple Negative Breast Neoplasms | 2021 |
Dalayed Effects of Antitumor Drug Paclitaxel on the Hereditary Material and Hemopoietic System of CBA Mice.
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Chromosome Aberrations; Cytogenetic Analysis; Erythropoiesis; Female; Genome; Genomic Instability; Hematopoiesis; Male; Mice; Mice, Inbred CBA; Mutagenicity Tests; Paclitaxel | 2020 |
Quantitative phosphoproteomics reveals mitotic function of the ATR activator ETAA1.
Topics: Antigens, Surface; Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia Mutated Proteins; Aurora Kinase B; Carrier Proteins; Chromosome Segregation; DNA Damage; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation, Neoplastic; Genomic Instability; HCT116 Cells; HEK293 Cells; Humans; M Phase Cell Cycle Checkpoints; Mitosis; Nuclear Proteins; Paclitaxel; Phosphorylation; Protein Interaction Maps; Proteomics; Signal Transduction | 2019 |
Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drugs, Investigational; Exome; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genomic Instability; High-Throughput Screening Assays; Humans; Imidazoles; MCF-7 Cells; Naphthoquinones; Paclitaxel; Sequence Analysis, DNA; Small Molecule Libraries; Tamoxifen | 2016 |
Patient-Derived Xenograft Models of Epithelial Ovarian Cancer for Preclinical Studies.
Topics: Adult; Animals; Antineoplastic Agents; Biomarkers, Tumor; Biopsy; Carboplatin; Carcinoma, Ovarian Epithelial; Disease Models, Animal; Drug Evaluation, Preclinical; ErbB Receptors; Female; Genomic Instability; Heterografts; Humans; Mice; Middle Aged; Molecular Targeted Therapy; Neoplasm Grading; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Translational Research, Biomedical; Xenograft Model Antitumor Assays | 2017 |
PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.
Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Centromere; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; DNA Copy Number Variations; Drug Resistance, Neoplasm; Female; Gene Amplification; Gene Editing; Gene Knockout Techniques; Genomic Instability; Genotype; Humans; Mice; Mutation; Paclitaxel; Phenotype; Tumor Suppressor Protein p53 | 2017 |
Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair.
Topics: Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Chromosome Aberrations; DNA Breaks, Double-Stranded; DNA Repair; DNA-Binding Proteins; Genomic Instability; Humans; Infrared Rays; Karyotyping; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; PTEN Phosphohydrolase; Rad51 Recombinase; RNA, Small Interfering; Telomere; Tumor Suppressor Proteins | 2009 |
Protoplast mutation and genome shuffling induce the endophytic fungus Tubercularia sp. TF5 to produce new compounds.
Topics: China; Chromatography, Thin Layer; Cytochalasins; Diterpenes; DNA Shuffling; DNA, Fungal; Fermentation; Genome, Fungal; Genomic Instability; Hyphae; Hypocreales; Mass Spectrometry; Mutation; Paclitaxel; Plants, Medicinal; Protoplasts; Sesquiterpenes; Tetralones; Ultraviolet Rays | 2010 |
Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Down-Regulation; Doxorubicin; Etoposide; Floxuridine; Fluorescent Antibody Technique; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomic Instability; Humans; Irinotecan; Metaphase; Paclitaxel; Polymerase Chain Reaction; Predictive Value of Tests; Protein Array Analysis; Reproducibility of Results; Tegafur; Tissue Array Analysis; Tumor Cells, Cultured; Up-Regulation; Uracil | 2012 |
4E-BP1 participates in maintaining spindle integrity and genomic stability via interacting with PLK1.
Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Centrosome; Chromosomes, Human; DNA, Neoplasm; Drug Screening Assays, Antitumor; Genomic Instability; HeLa Cells; Hep G2 Cells; Humans; Mitosis; Paclitaxel; Phosphoproteins; Phosphorylation; Polo-Like Kinase 1; Polyploidy; Protein Binding; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Spindle Apparatus | 2012 |
DNA cleavage and Trp53 differentially affect SINE transcription.
Topics: Antineoplastic Agents; Cisplatin; DNA Cleavage; DNA Damage; Etoposide; Genomic Instability; Humans; Paclitaxel; Short Interspersed Nucleotide Elements; Thiobarbiturates; Topoisomerase II Inhibitors; Transcription, Genetic; Tumor Suppressor Protein p53; Up-Regulation; Vincristine | 2007 |
A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.
Topics: Antimitotic Agents; Calcium-Binding Proteins; Cell Cycle Proteins; Chromosome Segregation; Gene Library; Genomic Instability; Genomics; HeLa Cells; Humans; Kinetochores; Mad2 Proteins; MAP Kinase Kinase Kinases; Mitosis; Mutation; Nocodazole; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; Repressor Proteins; Reproducibility of Results; RNA Interference; Signal Transduction; Spindle Apparatus; Time Factors; Transfection; Tubulin Modulators | 2007 |
BUB1 mediation of caspase-independent mitotic death determines cell fate.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis Inducing Factor; Benzoquinones; Caco-2 Cells; Caspases; Cell Line, Tumor; Chromosomes; Cold Temperature; DNA Fragmentation; DNA-Binding Proteins; Endodeoxyribonucleases; Enzyme Activation; Genomic Instability; HCT116 Cells; HeLa Cells; Humans; Lactams, Macrocyclic; Mitosis; Models, Biological; Nocodazole; Nuclear Proteins; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Tumor Protein p73; Tumor Suppressor Proteins | 2007 |