paclitaxel has been researched along with Disease Models, Animal in 572 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 26 (4.55) | 18.2507 |
2000's | 126 (22.03) | 29.6817 |
2010's | 337 (58.92) | 24.3611 |
2020's | 83 (14.51) | 2.80 |
Authors | Studies |
---|---|
Fairchild, C; Johnston, K; Kadow, JF; Lee, FL; Long, BH; Rose, WC; Vyas, DM; Wittman, MD | 1 |
Chai, H; Cordell, GA; Farnsworth, NR; Hollingshead, MG; Kardono, LB; Kinghorn, AD; Lantvit, D; Lee, IS; Mayo, JG; Mi, Q; Ngassapa, O; Peraza-Sánchez, S; Pezzuto, JM; Reyes-Lim, E; Riswan, S; Zhao, W | 1 |
Cai, S; Han, H; Jiang, J; Jiang, W; Jiang, X; Larrick, JW; Li, L; Tian, Z; Wang, Y; Wright, SC; Xiao, Y; Zhang, Z | 1 |
Akiyama, T; Bastow, KF; Cragg, G; Fujitake, M; Goto, M; Hung, MC; Kim, Y; Lai, CY; Lang, JY; Lee, EY; Lee, KH; Morris-Natschke, SL; Nakagawa-Goto, K; Newman, DJ; Sakurai, N; Takeya, K; Taniguchi, M; Usami, Y | 1 |
Carlson, EM; Cheng, H; Condon, K; Du, H; Eckley, S; Hu, Y; Jiang, Y; Kumar, V; Lewis, BM; Littlefield, BA; Narayan, S; Saxton, P; Schuck, E; Seletsky, BM; Tendyke, K; Towle, MJ; Yu, MJ; Zhang, H; Zheng, W | 1 |
Christodoulou, MS; Colombo, F; De Cesare, M; Ieronimo, G; Passarella, D; Zuco, V; Zunino, F | 1 |
Cichewicz, RH; Du, L; King, JB; Mooberry, SL; Robles, AJ | 1 |
Babaev, VM; Belenok, MG; Kataev, VE; Mironov, VF; Rizvanov, IKh; Semenov, VV; Semenova, MN; Strobykina, IY | 1 |
Dymock, BW; Kitagawa, M; Lee, KH; Lee, SH; Liao, PJ; See, CS; Wong, J | 1 |
Gu, Y; Hu, L; Liu, Y; Sun, L; Wu, Y | 1 |
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
An, R; Guo, C; Guo, MB; Hou, Z; Mou, YH; Wang, X; Xu, H; Yan, ZZ; Zhang, R | 1 |
Chen, JP; Chen, N; Ge, MM; Li, DY; Liu, DQ; Tian, YK; Wang, XM; Ye, DW; Zhou, YQ | 1 |
Koizumi, S; Komatsu, R; Mizuno, K; Shibata, K; Takanashi, K | 1 |
Liang, M; Ma, X; Sun, ZJ; Xiao, Y; Xu, Z; Yang, LL; Yang, QC; Yang, SC; Zhang, T | 1 |
Cortez, IL; Cunha, TM; Dos Santos, JC; Gomes, FIF; Gomes, FV; Guimarães, FS; Lopes, AHP; Mechoulam, R; Silva, CEA; Silva, NR | 1 |
Ali, MY; Ebeid, K; Griguer, C; Naguib, Y; Oliva, C; Quarterman, JC; Salem, AK; Wiwatchaitawee, K | 1 |
Aicher, SA; Blum, C; Hamity, MV; Hammond, DL; Hegarty, DM; Kolker, SJ; Langmack, L | 1 |
Abi Jaoude, J; Delahoussaye, AM; Feng, N; Fowlkes, N; Fujimoto, TN; Garcia Garcia, CJ; Gay, JP; Green, M; Marszalek, J; Molkentine, J; Taniguchi, CM | 1 |
Chen, T; He, Y; Lu, H; Pang, Z; Wang, Y | 1 |
Avella, DM; Chaudhuri, AA; Kaifi, JT; Kimchi, ET; Li, G; Manjunath, Y; Mitchem, JB; Nussbaum, YI; Pantel, K; Radhakrishnan, V; Shyu, CR; Staveley-O'Carroll, KF; Suvilesh, KN; Warren, WC | 1 |
Bao, S; Cai, J; Jin, Y; Wu, D | 1 |
Carvalho, PO; Costalonga, EC; Maranhão, RC; Noronha, IL; Pepineli, R; Silva, FMO | 1 |
Akbari, V; Emami, J; Hejazi, E; Lavasanifar, A; Minaiyan, M; Rezazadeh, M | 1 |
Cavalli, J; Cristina Dalazen Gonçalves, E; Daniele Bobermin, L; de Assis, PM; Dutra, RC; Gomez, MV; Quincozes-Santos, A; Raposo, NRB | 1 |
Bharti, S; Dhiman, S; Goswami, A; Manhas, D; Mir, KB; Nandi, U; Sharma, DK; Tripathi, N; Wazir, P | 1 |
Han, H; Healey, AJ; Kvåle, S; Ng, S; Sontum, PC; Sulheim, E; Torp, SH; Von Hoff, D | 1 |
Choi, SK; Hwang, SY; Jeon, S; Kwon, Y; Lee, J; Lee, YS; Na, Y; Shin, JH; Yoo, H | 1 |
Cai, J; Chen, J; Huang, C; Li, C; Li, M; Wang, B; Wang, J; Zhang, JV; Zhang, P; Zhou, W | 1 |
Tian, H; Wang, L; Zhang, Z | 1 |
Dong, P; Geng, Q; Liu, N; Wang, HM; Yang, JY; Zhang, Y | 1 |
Chu, T; Han, B; Lou, Y; Lu, J; Wang, H; Zhang, W; Zhang, X; Zhang, Y; Zhong, H; Zhong, R | 1 |
Jin, Z; Ma, X; Ni, R; Pan, Y; Wu, Q; Yang, G | 1 |
Ahire, C; Balasubramanian, P; Campisi, J; Csipo, T; Csiszar, A; DelFavero, J; Faakye, JA; Gulej, R; Kiss, T; Kuan-Celarier, A; Mukli, P; Nagaraja, R; Nyul-Toth, A; Tang, Q; Tarantini, A; Tarantini, S; Ungvari, A; Ungvari, Z; Yabluchanskiy, A; Yan, F | 1 |
Allard, J; Bellina, M; Bernet, A; Blanpain, C; Braissand, N; Cassier, PA; Dalban, C; Decaestecker, C; Degletagne, C; Delord, JP; Devouassoux-Shisheboran, M; Dolcet, X; Ducarouge, B; Fattet, L; Gadot, N; Garin, G; Gheit, H; Hernandez-Vargas, H; Jelin, R; Lengrand, J; Léon, S; Matias-Guiu, X; Mehlen, P; Mery-Lamarche, E; Navaridas, R; Neves, D; Paradisi, A; Pastushenko, I; Perol, D; Rama, N; Ray-Coquard, I; Salmon, I; Zindy, E | 1 |
Dadey, DY; Fitzpatrick, J; Hallahan, DE; Kapoor, V; Rau, MJ; Saikia, M; Shah, HK; Singh, AK; Thotala, D; Townsend, R | 1 |
Adir, O; Alyan, M; Binenbaum, Y; Dvir, T; Fridman, E; Gibori, H; Gil, Z; Hershkovitz, D; Kasten, S; Koren, L; Krayem, M; Krinsky, N; Liba, L; Lübtow, MM; Luxenhofer, R; Milman, N; Mumblat, Y; Noor, N; Ofir, S; Poley, M; Satchi-Fainaro, R; Schroeder, A; Shainsky-Roitman, J; Shklover, J; Simon, A; Yaari, Z; Zinger, A | 1 |
Anderson, JA; Engebretson, D; Evans, R; Fuglsby, K; Kelly, P; Lamichhane, S; Pohlson, K; Remund, T | 1 |
Gao, M; Jiang, C; Jin, Q; Wang, F; Yao, N; Zhang, D; Zhang, J | 1 |
Falah, M; Rayan, A; Rayan, M | 1 |
Han, JY; Li, CY; Li, GQ; Li, XL; Liang, AH; Liu, SY; Pan, C; Tian, JZ; Wang, LM; Xian, Z; Yi, Y; Zhang, YS; Zhao, Y | 1 |
Gao, X; Ma, Y; Qian, J; Qian, Q; Shi, L; Yang, J; Zhang, Z; Zhu, X | 1 |
Chu, K; Han, L; Li, T; Ouyang, H; Qiu, L; Wang, X; Xu, W; Zhang, X | 1 |
Abd-Elrazek, AM; El-Dash, HA; Said, NI | 1 |
Figg, WD; Kindrick, J; Li, M; Nguyen, L; Peer, CJ; Rajaputra, P; Subramaniyan, B; Woo, S; You, Y | 1 |
Byrne, M; Byron, K; Chen, YC; Dear, AE; Gaspari, TA; Kaye, DM; Liu, H; Ozcelik, B; Perlmutter, P; Sama, GR; Subbiah, J; Walker, A; Widdop, RE | 1 |
Adamson, T; Borneman, J; Cantin, EM; Corleto, J; Ermel, R; Logan, GD; McKemy, D; Mendonca, S; Peacock, BB; Ramakrishna, C; Ruegger, PM; Yamaki, S | 1 |
Baker, D; Cole, T; Faccio, R; Faget, DV; Luo, X; Monahan, J; Murali, B; Ren, Q; Ricci, B; Schwarz, JK; Stewart, SA; Thotala, D; van Deursen, JM; Yao, Z | 1 |
Elibol, B; Kilic, U; Orhan, C; Ozercan, IH; Qazi, S; Sahin, K; Sahin, TK; Tuzcu, M; Uckun, FM | 1 |
Chu, NQ; Colby, A; Colson, YL; de Forcrand, C; Grinstaff, MW; Liu, R; Padera, RF | 1 |
Chen, X; Fu, Y; Gong, T; Hu, Y; Wang, M; Yu, R; Zhang, ZR | 1 |
Bai, XH; Deng, J; Ding, HH; Liu, M; Luo, DX; Mai, JW; Ruan, XC; Xin, WJ; Xu, T; Yang, YL; Zhang, SB; Zhang, XQ; Zhang, XZ | 1 |
Gong, Y; Huang, P; Liu, H; Ren, X; Wang, J; Weng, M; Yang, X; Yu, Z; Zheng, L; Zheng, Q | 1 |
Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; 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Burris, HA | 2 |
Houri, JM; O'Sullivan, FX | 1 |
Woolf, AS | 1 |
Miao, SY; Pelayo, JC; Woo, DD; Woolf, AS | 1 |
Banquerigo, ML; Brahn, E; Tang, C | 1 |
Rodriguez, M; Steren, AJ | 1 |
Albeck, M; Dovrat, S; Kalechman, Y; Mettinger, K; Shani, A; Sredni, B; Whisnant, JK | 1 |
Adachi, M; Kishida, S; Saitoh, Y; Takeyama, Y; Toyokawa, A; Ueda, T; Yamamoto, M | 1 |
Hampel, G; Rübe, C; Schuck, A; Willich, N | 1 |
Dorr, RT; Liddil, JD; Snead, K | 1 |
Capizzi, RL; Johnson, CS; Lopez, MH; Paine, GD; Taylor, CW | 1 |
Rowinsky, EK | 1 |
Hortobágyi, G | 1 |
Ara, G; Frei, E; Herbst, RS; Keyes, SR; Teicher, BA | 1 |
Arsenault, AL; Banquerigo, ML; Brahn, E; Hunter, WL; Lhoták, S | 1 |
Dell, J; Gurnani, M; Hajian, G; Lipari, P; Nielsen, LL | 1 |
Canada, AL; Ross, HJ; Slater, LM | 1 |
Deisseroth, AB; Hanania, EG | 1 |
Apfel, SC | 1 |
Hortobagyi, GN; Hung, MC; Lau, YK; Xia, W; Zhang, L | 1 |
Fuchs, J; Habild, G; Haindl, J; Knop, E; Leuschner, I; Schweinitz, DV | 1 |
Asano, S; Hibino, H; Ikebuchi, K; Nakahata, T; Nakazaki, Y; Sugimoto, Y; Sugiyama, H; Suzuki, S; Takahashi, S; Tanabe, T; Tani, K; Tanioka, Y; Tojo, A; Wu, MS | 1 |
Arakawa, H; Harada, N; Hashiyama, T; Nakanishi, N; Oda, K; Ozaki, K; Tsujihara, K; Yamaguchi, T | 1 |
Appelt, K; Bloom, LA; Brekken, J; McDermott, CD; Shalinsky, DR; Varki, NM; Zook, S; Zou, H | 1 |
Bohling, CA; Forrest, LJ; Hershey, AE; Imondi, AR; Kurzman, ID; Placke, ME; Stonerook, M; Vail, DM | 1 |
Atassi, G; Burbridge, MF; Guilbaud, N; Kraus-Berthier, L; Naze, M; Pierre, A | 1 |
Gleave, ME; Miayake, H; Tolcher, A | 1 |
Au, JL; Jang, SH; Wientjes, MG | 1 |
Hershberger, PA; Johnson, CS; Modzelewski, RA; Rueger, RM; Trump, DL; Yu, WD | 1 |
Fujimoto-Ouchi, K; Tanaka, Y; Tominaga, T | 1 |
Abella, BS; Brinker, JA; Bunge, KE; Cheng, L; Froehlich, JP; Heldman, AW; Heller, PF; Hruban, RH; Hunter, WL; Jenkins, GM; Kim, DW; Kinsella, JL; Lakatta, EG; Nater, C; Rezai, B; Sollott, SJ; Ware, M | 1 |
Borzilleri, R; Fairchild, CR; Kim, SH; Kramer, RA; Lee, FY; Long, BH; Reventos-Suarez, C; Rose, WC; Vite, GD | 1 |
Bittner, C; Feyerabend, T; Peters, SO; Raap, M; Remmert, S; Robins, IH; Sieg, P; Sommer, K; Wiedemann, GJ | 1 |
Chi, K; Gleave, ME; July, L; Miyake, H; Nelson, C; Rennie, P; Zellweger, T | 1 |
Cheema, SS; Kilpatrick, TJ; Lopes, EC; Phan, S; Reardon, K | 1 |
Al Ghobainy, R; Baumbach, A; Cetin, S; Herdeg, C; Horch, B; Karsch, KR; Küttner, A; Oberhoff, M | 1 |
Brenneman, DC; Chan, D; Fridkin, M; Gelber, E; Gozes, I; Levy, A; Leyton, J; Moody, TW | 1 |
Bramwell, O; Hong, MK; Kornowski, R; Leon, MB; Ragheb, AO | 1 |
Bennett, GJ; Clark, US; Mannes, AJ; Polomano, RC | 1 |
Hofmann, J; Hu, L; Jaffe, RB; Lu, Y; Mills, GB | 1 |
Baccarini, S; Bacigalupo, I; Barillari, G; Bugarini, R; Bussolino, F; Cafaro, A; Carlei, D; Ensoli, B; Falchi, M; Leone, P; Malavasi, L; Monini, P; Palladino, C; Rezza, G; Sgadari, C; Toschi, E; Valdembri, D | 1 |
Burke, PA; DeNardo, GL; DeNardo, SJ; Kukis, DL; Miers, LA | 1 |
Alila, H; Bunn, PA; Chan, DC; Earle, K; Helfrich, B; Kelly, K; Pamukcu, R; Piazza, G; Thompson, W; Whitehead, CM; Zhao, TL | 1 |
Duray, PH; Figg, WD; Fisher, BA; Flynn, BM; Nguyen, DM; Schrump, DS; Terrill, RE; Weiser, TS; Zhai, S | 1 |
Larsson, LI; Lichtenberg, J | 1 |
Hu, J; Li, L; Ma, P; Zhang, S; Zhu, H | 1 |
Abdullah, SM; Gilani, SN; Gul, F; Ismail, M; Kaleem, WA; Khan, H; Khan, I; Khan, N; Nisar, M; Qayum, M; Shah, H; Shah, MR; Ullah, M | 1 |
Liang, ZS; Wang, LH; Yang, WX; Yu, SJ; Zhao, ZG | 1 |
Brandon, TA; Curry, SC; Gerkin, R; Graeme, KA; Miller, MB; Reagan, CG; Ruha, AM; Tanen, DA | 1 |
Du Nguyen, H; Horaguchi, Y; Kasanami, Y; Kawabata, A; Kitamura, S; Nishikawa, H; Okada, T; Sekiguchi, F; Toyooka, N; Tsubota, M; Yamaoka, S; Yoshida, S | 1 |
23 review(s) available for paclitaxel and Disease Models, Animal
Article | Year |
---|---|
Goshajinkigan attenuates paclitaxel-induced neuropathic pain via cortical astrocytes.
Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Hyperalgesia; Mice; Neuralgia; Paclitaxel; Somatosensory Cortex | 2021 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
The Uniqueness of Albumin as a Carrier in Nanodrug Delivery.
Topics: Albumins; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Carriers; Half-Life; Humans; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Neoplasms; Paclitaxel; Serum Albumin, Human | 2021 |
Preclinical and Clinical Evidence of Therapeutic Agents for Paclitaxel-Induced Peripheral Neuropathy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Clinical Trials as Topic; Disease Models, Animal; Humans; Oxidative Stress; Paclitaxel; Peripheral Nervous System Diseases; Pre-Exposure Prophylaxis; Translational Research, Biomedical | 2021 |
Modulating the endocannabinoid pathway as treatment for peripheral neuropathic pain: a selected review of preclinical studies.
Topics: Animals; Antineoplastic Agents; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cisplatin; Disease Models, Animal; Endocannabinoids; Evaluation Studies as Topic; Hyperalgesia; Mice; Neuralgia; Paclitaxel; Rats; Signal Transduction | 2017 |
Antimicrotubule Agent-Induced Zinc Neurotoxicity.
Topics: Animals; Cation Transport Proteins; Cell Death; Cognitive Dysfunction; Colchicine; Disease Models, Animal; Hippocampus; Humans; Mice; Microtubules; Neurogenesis; Neurons; Neurotoxicity Syndromes; Paclitaxel; Presynaptic Terminals; Tubulin Modulators; Vincristine | 2018 |
Rodent models of chemotherapy-induced peripheral neuropathy.
Topics: Animals; Antineoplastic Agents; Axons; Boronic Acids; Bortezomib; Cisplatin; Disease Models, Animal; Mice; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases; Pyrazines; Rats; Vincristine | 2014 |
Cell-penetrating, guanidinium-rich molecular transporters for overcoming efflux-mediated multidrug resistance.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line, Tumor; Cell Membrane; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Guanidine; Humans; Mice; Oligopeptides; Ovarian Neoplasms; Paclitaxel; Peptides; Protein Transport; RNA Interference; Solubility; Water | 2014 |
Syngeneic mouse model of epithelial ovarian cancer: effects of nanoparticulate paclitaxel, Nanotax.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Delivery Systems; Female; Humans; Injections, Intralesional; Injections, Intraperitoneal; Mice; Nanoparticles; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Transplantation, Isogeneic | 2008 |
Taxol: efficacy against oral squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Survival; Clinical Trials as Topic; Disease Models, Animal; Drug Therapy, Combination; Humans; Mouth Neoplasms; Paclitaxel; Platinum Compounds; Survival Rate; Tongue Neoplasms | 2013 |
Neuropathic pain associated with non-surgical treatment of breast cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease Models, Animal; Female; Humans; Neuralgia; Paclitaxel; Peripheral Nerves; Peripheral Nervous System Diseases; Radiation Injuries; Radiotherapy; Rats | 2005 |
Update on drug-eluting stents for prevention of restenosis.
Topics: Animals; Anti-Bacterial Agents; Coronary Restenosis; Disease Models, Animal; Drug Delivery Systems; Drug-Eluting Stents; Humans; Paclitaxel; Prosthesis Design; Sirolimus; Tubulin Modulators | 2006 |
Drug-eluting stents studies in mice: do we need atherosclerosis to study restenosis?
Topics: Animals; Atherosclerosis; Coronary Restenosis; Disease Models, Animal; Drug Delivery Systems; Drug Evaluation, Preclinical; Humans; Mice; Paclitaxel; Sirolimus; Stents | 2006 |
Vascular responses to drug eluting stents: importance of delayed healing.
Topics: Aged; Angioplasty, Balloon, Coronary; Animals; Biopsy, Needle; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Disease Models, Animal; Endothelium, Vascular; Humans; Immunohistochemistry; Middle Aged; Paclitaxel; Prognosis; Prosthesis Design; Rabbits; Risk Factors; Sensitivity and Specificity; Sirolimus; Stents; Time Factors; Wound Healing | 2007 |
The significance of preclinical evaluation of sirolimus-, paclitaxel-, and zotarolimus-eluting stents.
Topics: Animals; Antineoplastic Agents; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Humans; Iliac Artery; Paclitaxel; Rabbits; Sirolimus; Swine; Time Factors; Tunica Intima | 2007 |
Preclinical investigations with epothilones in breast cancer models.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Capecitabine; Cell Line, Tumor; Clinical Trials, Phase I as Topic; Deoxycytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Epothilones; Female; Fluorouracil; Humans; Mice; Mice, Nude; Microtubules; Paclitaxel; Tubulin Modulators | 2008 |
Animal models in rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Cell Adhesion; Cytokines; Disease Models, Animal; Humans; Major Histocompatibility Complex; Mice; Mice, SCID; Mice, Transgenic; Nitric Oxide; Paclitaxel; Synovitis; T-Lymphocytes | 1995 |
[Combined effect of Paclitaxel and ionizing radiation. Experimental data of in-vitro and in-vivo models].
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Chemotherapy, Adjuvant; Disease Models, Animal; Humans; Neoplasms, Experimental; Paclitaxel; Radiation-Sensitizing Agents; Radiotherapy Dosage; Radiotherapy, Adjuvant; Tumor Cells, Cultured | 1996 |
The taxanes: dosing and scheduling considerations.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease Models, Animal; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; In Vitro Techniques; Lung Neoplasms; Ovarian Neoplasms; Paclitaxel | 1997 |
Docetaxel in breast cancer and a rationale for combination therapy.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Models, Animal; Docetaxel; Drug Resistance, Neoplasm; Female; Humans; In Vitro Techniques; Mice; Paclitaxel; Taxoids | 1997 |
Docetaxel in combination with fluorouracil for advanced solid tumors.
Topics: Adult; Aged; Animals; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Disease Models, Animal; Docetaxel; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Leucovorin; Mice; Middle Aged; Mucous Membrane; Neoplasms; Neutropenia; Paclitaxel; Taxoids | 1997 |
Neurotrophic factors and diabetic peripheral neuropathy.
Topics: Animals; Diabetic Neuropathies; Disease Models, Animal; Humans; Nerve Compression Syndromes; Nerve Growth Factors; Paclitaxel; Peripheral Nervous System Diseases; Vinblastine | 1999 |
Preclinical and clinical studies of docetaxel and exisulind in the treatment of human lung cancer.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Disease Models, Animal; Docetaxel; Humans; Immunohistochemistry; Lung Neoplasms; Mice; Paclitaxel; Rats; Sulindac; Survival Analysis; Taxoids; Treatment Outcome; Tumor Cells, Cultured | 2002 |
8 trial(s) available for paclitaxel and Disease Models, Animal
Article | Year |
---|---|
Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer.
Topics: Animals; Biopsy; Carboplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Endometrial Neoplasms; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Humans; Mice; Netrin-1; Paclitaxel; RNA-Seq; Single-Cell Gene Expression Analysis; Tumor Microenvironment | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
High-dose parenteral ascorbate enhanced chemosensitivity of ovarian cancer and reduced toxicity of chemotherapy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Carboplatin; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Infusions, Parenteral; Mice; Ovarian Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays | 2014 |
Pharmacological Modulation of the Mitochondrial Electron Transport Chain in Paclitaxel-Induced Painful Peripheral Neuropathy.
Topics: Animals; Antimycin A; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Electron Transport; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Hyperalgesia; Male; Motor Activity; Paclitaxel; Pain; Pain Measurement; Peripheral Nervous System Diseases; Psychomotor Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Single-Blind Method; Time Factors | 2015 |
SPARC Expression Did Not Predict Efficacy of nab-Paclitaxel plus Gemcitabine or Gemcitabine Alone for Metastatic Pancreatic Cancer in an Exploratory Analysis of the Phase III MPACT Trial.
Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Deoxycytidine; Disease Models, Animal; Female; Gemcitabine; Gene Expression; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Mice, Knockout; Neoplasm Metastasis; Osteonectin; Paclitaxel; Pancreatic Neoplasms; Stromal Cells; Treatment Outcome; Xenograft Model Antitumor Assays | 2015 |
In vivo evaluation of intravesical paclitaxel and combined bcl-xL antisense oligodeoxynucleotide treatment for orthotopic urothelial carcinoma.
Topics: Administration, Intravesical; Animals; Antineoplastic Agents, Phytogenic; bcl-X Protein; Carcinoma; Combined Modality Therapy; Disease Models, Animal; Humans; Kidney; Oligonucleotides, Antisense; Paclitaxel; Rats; Rats, Nude; Urinary Bladder Neoplasms; Urologic Neoplasms | 2009 |
The anti-tumor agent sagopilone shows antiresorptive effects both in vitro and in vivo.
Topics: Animals; Benzothiazoles; Bone Density; Bone Resorption; Disease Models, Animal; Epothilones; Female; Humans; Mice; Osteoclasts; Osteoporosis; Ovariectomy; Paclitaxel; Tubulin Modulators | 2011 |
Dose-dense chemotherapy improves mechanisms of antitumor immune response.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Immunoassay; Maximum Tolerated Dose; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasms, Experimental; Ovarian Neoplasms; Paclitaxel | 2013 |
542 other study(ies) available for paclitaxel and Disease Models, Animal
Article | Year |
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Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Chlorambucil; Disease Models, Animal; Female; Humans; Inhibitory Concentration 50; Mice; Neoplasm Transplantation; Ovarian Neoplasms; Paclitaxel; Sarcoma; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2001 |
Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests.
Topics: Animals; Biological Factors; Colonic Neoplasms; Diosgenin; Disease Models, Animal; Diterpenes; Drug Screening Assays, Antitumor; Female; Heterocyclic Compounds, 3-Ring; HL-60 Cells; Humans; Inhibitory Concentration 50; KB Cells; Leukemia P388; Male; Melanoma; Mice; Molecular Structure; Naphthoquinones; Ovarian Neoplasms; Paclitaxel; Polymers; Prostatic Neoplasms; Triterpenes; Tumor Cells, Cultured | 2002 |
Synthesis and antitumor activity evaluations of albumin-binding prodrugs of CC-1065 analog.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Disease Models, Animal; Duocarmycins; Female; Humans; Indoles; Mice; Molecular Structure; Neoplasm Transplantation; Neoplasms; Prodrugs; Serum Albumin; Structure-Activity Relationship | 2008 |
Antitumor Agents. 282. 2'-(R)-O-acetylglaucarubinone, a quassinoid from Odyendyea gabonensis as a potential anti-breast and anti-ovarian cancer agent.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Humans; KB Cells; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Quassins; Stereoisomerism | 2010 |
Novel second generation analogs of eribulin. Part III: Blood-brain barrier permeability and in vivo activity in a brain tumor model.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Furans; Inhibitory Concentration 50; Ketones; Mice; Mice, Inbred BALB C | 2011 |
Synthesis and biological evaluation of imidazolo[2,1-b]benzothiazole derivatives, as potential p53 inhibitors.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Ovarian Neoplasms; Toluene; Transplantation, Heterologous; Tumor Suppressor Protein p53 | 2011 |
Cytotoxic dimeric epipolythiodiketopiperazines from the ascomycetous fungus Preussia typharum.
Topics: Animals; Antineoplastic Agents; Ascomycota; ATP Binding Cassette Transporter, Subfamily B, Member 1; Disease Models, Animal; Drug Screening Assays, Antitumor; Humans; Melanoma; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Piperazines | 2014 |
Triphenylphosphonium Cations of the Diterpenoid Isosteviol: Synthesis and Antimitotic Activity in a Sea Urchin Embryo Model.
Topics: Animals; Antimitotic Agents; Antineoplastic Agents; Cations; Disease Models, Animal; Diterpenes; Diterpenes, Kaurane; Humans; Mediterranean Sea; Mitochondria; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organophosphorus Compounds; Sea Urchins; Structure-Activity Relationship | 2015 |
Prodrugs of the cancer cell selective anti-cancer agent (Z)-2-(1H-indol-3-yl)-3-(isoquinolin-5-yl)acrylonitrile (A131) are orally efficacious in a mouse model of resistant colon cancer.
Topics: Acrylonitrile; Administration, Oral; Animals; Antineoplastic Agents; Colonic Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Indoles; Isoquinolines; Mice; Molecular Structure; Neoplasms, Experimental; Paclitaxel; Prodrugs; Solubility; Structure-Activity Relationship | 2019 |
Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents.
Topics: Animals; Antineoplastic Agents; Carbazoles; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Rats; Solubility; Structure-Activity Relationship; Sulfonamides; Tumor Cells, Cultured; Water | 2020 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Lead optimization generates selenium-containing miconazole CYP51 inhibitors with improved pharmacological profile for the treatment of fungal infections.
Topics: 14-alpha Demethylase Inhibitors; Animals; Antifungal Agents; Binding Sites; Biofilms; Candida; Candidiasis; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Design; Half-Life; Humans; Mice; Miconazole; Microbial Sensitivity Tests; Molecular Docking Simulation; Selenium; Sterol 14-Demethylase; Structure-Activity Relationship | 2021 |
β2-adrenoreceptor agonist ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of mitochondrial biogenesis.
Topics: Adrenergic beta-2 Receptor Agonists; Analgesics; Animals; Disease Models, Animal; DNA, Mitochondrial; Formoterol Fumarate; Male; Mitochondria; Neuralgia; Organelle Biogenesis; Paclitaxel; Pain Threshold; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Spinal Cord | 2021 |
Microenvironment-Responsive Prodrug-Induced Pyroptosis Boosts Cancer Immunotherapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Drug Liberation; Female; Glutathione; Immunotherapy; Mice; Mice, Inbred BALB C; Paclitaxel; Photochemotherapy; Photosensitizing Agents; Prodrugs; Pyroptosis; Reactive Oxygen Species; Tumor Microenvironment | 2021 |
The Cannabidiol Analog PECS-101 Prevents Chemotherapy-Induced Neuropathic Pain via PPARγ Receptors.
Topics: Animals; Antineoplastic Agents; Cannabidiol; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Mice; Neuralgia; Paclitaxel; PPAR gamma | 2022 |
Surface Modification of Nanoparticles Enhances Drug Delivery to the Brain and Improves Survival in a Glioblastoma Multiforme Murine Model.
Topics: Animals; Brain; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Glioblastoma; Humans; Lactic Acid; Mice; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution | 2022 |
Nicotinamide Riboside Alleviates Corneal and Somatic Hypersensitivity Induced by Paclitaxel in Male Rats.
Topics: Animals; Corneal Diseases; Disease Models, Animal; Hypersensitivity; Male; Niacinamide; Paclitaxel; Rats; Rats, Sprague-Dawley; Tears; Vitamin B Complex | 2022 |
Feasibility of administering human pancreatic cancer chemotherapy in a spontaneous pancreatic cancer mouse model.
Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Disease Models, Animal; Feasibility Studies; Fluorouracil; Gemcitabine; Humans; Irinotecan; Leucovorin; Mice; Oxaliplatin; Paclitaxel; Pancreatic Neoplasms | 2022 |
Dual targeting micelles loaded with paclitaxel and lapatinib for combinational therapy of brain metastases from breast cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Blood-Brain Barrier; Brain; Brain Neoplasms; Breast Neoplasms; Disease Models, Animal; Drug Delivery Systems; Female; Humans; Injections, Intravenous; Lapatinib; Mice; Micelles; Paclitaxel; Peptides; Tumor Cells, Cultured | 2022 |
Tumorigenic circulating tumor cells from xenograft mouse models of non-metastatic NSCLC patients reveal distinct single cell heterogeneity and drug responses.
Topics: Animals; Carboplatin; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Heterografts; Humans; Lung Neoplasms; Mice; Neoplastic Cells, Circulating; Paclitaxel | 2022 |
Effect of CMB Carrying PTX and CRISPR/Cas9 on Endometrial Cancer Naked Mouse Model.
Topics: Animals; CRISPR-Cas Systems; Disease Models, Animal; Endometrial Neoplasms; Female; Glycogen Synthase Kinase 3; Humans; Mammals; Mice; Paclitaxel | 2022 |
Use of paclitaxel carried in solid lipid nanoparticles to prevent peritoneal fibrosis in rats.
Topics: Animals; Disease Models, Animal; Female; Liposomes; Male; Nanoparticles; Paclitaxel; Peritoneal Fibrosis; Peritoneum; Rats; Rats, Wistar; Transforming Growth Factor beta | 2022 |
An injectable thermosensitive hydrogel/nanomicelles composite for local chemo-immunotherapy in mouse model of melanoma.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hydrogels; Immunotherapy; Melanoma; Mice; Micelles; Paclitaxel; Poloxamer | 2022 |
Systemic, Intrathecal, and Intracerebroventricular Antihyperalgesic Effects of the Calcium Channel Blocker CTK 01512-2 Toxin in Persistent Pain Models.
Topics: Animals; Calcium Channel Blockers; Chronic Pain; Disease Models, Animal; Humans; Hyperalgesia; omega-Conotoxins; Paclitaxel; Spider Venoms | 2022 |
Rottlerin promotes anti-metastatic events by ameliorating pharmacological parameters of paclitaxel: An in-vivo investigation in the orthotopic mouse model of breast cancer.
Topics: Acetophenones; Animals; Apoptosis Regulatory Proteins; Benzopyrans; Cadherins; Cell Line, Tumor; Disease Models, Animal; Epithelial-Mesenchymal Transition; Humans; Mice; Paclitaxel; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Triple Negative Breast Neoplasms; Vimentin | 2022 |
Effect of acoustic cluster therapy (ACT®) combined with chemotherapy in a patient-derived xenograft mouse model of pancreatic cancer.
Topics: Acoustics; Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Disease Models, Animal; Heterografts; Humans; Mice; Paclitaxel; Pancreatic Neoplasms; Xenograft Model Antitumor Assays | 2022 |
Design, synthesis, and biological evaluation of novel HSP27 inhibitors to sensitize lung cancer cells to clinically available anticancer agents.
Topics: Animals; Antineoplastic Agents; Cisplatin; Disease Models, Animal; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Lung Neoplasms; Mice; Paclitaxel | 2023 |
Chondroitin Sulfate Targeting Nanodrug Achieves Near-Infrared Fluorescence-Guided Chemotherapy Against Triple-Negative Breast Primary and Lung Metastatic Cancer.
Topics: Animals; Chondroitin Sulfates; Disease Models, Animal; Humans; Lung; Lung Neoplasms; Mice; Nanospheres; Paclitaxel; Triple Negative Breast Neoplasms | 2022 |
Hsa_circ_0092887 targeting miR-490-5p/UBE2T promotes paclitaxel resistance in non-small cell lung cancer.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Humans; Lung Neoplasms; Mice; MicroRNAs; Paclitaxel; Ubiquitin-Conjugating Enzymes | 2023 |
TRIM6 Reduces Ferroptosis and Chemosensitivity by Targeting SLC1A5 in Lung Cancer.
Topics: Amino Acid Transport System ASC; Animals; Cell Death; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Ferroptosis; Humans; Lung Neoplasms; Mice; Minor Histocompatibility Antigens; Paclitaxel; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2023 |
Paclitaxel Has a Reduced Toxicity Profile in Healthy Rats After Polymeric Micellar Nanoparticle Delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Humans; Lung Neoplasms; Male; Mammals; Micelles; Nanoparticles; Paclitaxel; Peripheral Nervous System Diseases; Polymers; Rats; Rats, Sprague-Dawley | 2023 |
Zhuidu Formula suppresses the migratory and invasive properties of triple-negative breast cancer cells via dual signaling pathways of RhoA/ROCK and CDC42/MRCK.
Topics: Actins; Animals; Cell Adhesion; Cell Growth Processes; Cell Movement; Cytoskeleton; Disease Models, Animal; Drug Synergism; Ethnopharmacology; Female; Humans; Matrix Metalloproteinases; MDA-MB-231 Cells; Medicine, Chinese Traditional; Mice; Myotonin-Protein Kinase; Neoplasm Invasiveness; Neoplasm Metastasis; Paclitaxel; rho-Associated Kinases; Signal Transduction; Triple Negative Breast Neoplasms | 2023 |
Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain.
Topics: Animals; Chemotherapy-Related Cognitive Impairment; Cognitive Dysfunction; Disease Models, Animal; Endothelial Cells; Mice; Paclitaxel; Senotherapeutics | 2023 |
Blocking the functional domain of TIP1 by antibodies sensitizes cancer to radiation therapy.
Topics: Animals; Antibodies; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Glioblastoma; Humans; Lung Neoplasms; Mice; Paclitaxel | 2023 |
Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors.
Topics: Adenocarcinoma; Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Membrane Permeability; Collagen; Collagenases; Disease Models, Animal; Extracellular Matrix; Fibrosis; Humans; Liposomes; Mice; Nanoparticles; Paclitaxel; Pancreas; Tumor Microenvironment | 2019 |
Development of drug-coated balloon for the treatment of multiple peripheral artery segments.
Topics: Angioplasty, Balloon; Animals; Cardiovascular Agents; Coated Materials, Biocompatible; Disease Models, Animal; Paclitaxel; Particulate Matter; Peripheral Arterial Disease; Swine; Vascular Patency | 2020 |
Enhancing intratumoral biodistribution and antitumor activity of nab-paclitaxel through combination with a vascular disrupting agent, combretastatin A-4-phosphate.
Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Female; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Paclitaxel; Rats; Stilbenes; Tissue Distribution | 2019 |
A Novel Paclitaxel Conjugate with Higher Efficiency and Lower Toxicity: A New Drug Candidate for Cancer Treatment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Paclitaxel; Thioctic Acid; Xenograft Model Antitumor Assays | 2019 |
The Involvement of the RhoA/ROCK Signaling Pathway in Hypersensitivity Reactions Induced by Paclitaxel Injection.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biopsy; Complement Activation; Complement System Proteins; Disease Models, Animal; Drug Hypersensitivity; Female; Histamine Release; Male; Mice; Paclitaxel; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2019 |
A Paclitaxel-Based Mucoadhesive Nanogel with Multivalent Interactions for Cervical Cancer Therapy.
Topics: Acrylic Resins; Adhesiveness; Animals; beta-Cyclodextrins; Cell Death; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Disease Models, Animal; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endocytosis; Female; Humans; Mice, Inbred BALB C; Mice, Nude; Mucins; Mucus; Nanogels; Paclitaxel; Solubility; Uterine Cervical Neoplasms | 2019 |
Evaluation of intestinal permeation enhancement with carboxymethyl chitosan-rhein polymeric micelles for oral delivery of paclitaxel.
Topics: Administration, Oral; Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Humans; Intestinal Mucosa; Male; Mice; Micelles; Neoplasms; Paclitaxel; Permeability; Rats; Tissue Distribution; Verapamil | 2020 |
The role of propolis against paclitaxel-induced oligospermia, sperm abnormality, oxidative stress and DNA damage in testes of male rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Apitherapy; Disease Models, Animal; DNA Damage; Humans; Male; Neoplasms; Oligospermia; Oxidative Stress; Paclitaxel; Propolis; Rats; Semen; Sperm Motility; Testis | 2020 |
Local and Systemic Antitumor Effects of Photo-activatable Paclitaxel Prodrug on Rat Breast Tumor Models.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease Models, Animal; Female; Humans; Paclitaxel; Photochemotherapy; Prodrugs; Rats; Rats, Inbred F344 | 2020 |
A Novel Epigenetic Drug-Eluting Balloon Angioplasty Device: Evaluation in a Large Animal Model of Neointimal Hyperplasia.
Topics: Angioplasty, Balloon; Animals; Carotid Artery Diseases; Carotid Artery, Common; Cell Proliferation; Cells, Cultured; Coated Materials, Biocompatible; Disease Models, Animal; Epigenesis, Genetic; Equipment Design; Female; Histone Deacetylase Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Inflammation Mediators; Neointima; Paclitaxel; Sheep, Domestic; Time Factors; Vascular Access Devices | 2019 |
Dominant Role of the Gut Microbiota in Chemotherapy Induced Neuropathic Pain.
Topics: Animals; Antineoplastic Agents; Biodiversity; Brain; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Male; Mice; Microglia; Neuralgia; Paclitaxel; Spinal Cord | 2019 |
Therapy-Induced Senescence Drives Bone Loss.
Topics: Animals; Antineoplastic Agents; Cellular Senescence; Disease Models, Animal; Doxorubicin; Femur; Humans; Injections, Intraperitoneal; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Mice, Transgenic; Neoplasms; Osteoporosis; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Protein Serine-Threonine Kinases; X-Ray Microtomography | 2020 |
Chemopreventive efficacy of stampidine in a murine breast cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Breast Neoplasms; Dideoxynucleotides; Disease Models, Animal; Disease-Free Survival; Female; Mice; Mice, Inbred BALB C; Paclitaxel; Stavudine; Survival Rate; Thymidine Monophosphate; Time Factors | 2020 |
Paclitaxel-loaded expansile nanoparticles improve survival following cytoreductive surgery in pleural mesothelioma xenografts.
Topics: Animals; Cell Line, Tumor; Combined Modality Therapy; Cytoreduction Surgical Procedures; Disease Models, Animal; Disease Progression; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mice; Nanoparticles; Paclitaxel; Pleural Neoplasms; Pneumonectomy; Tumor Burden; Xenograft Model Antitumor Assays | 2020 |
Low-dose paclitaxel via hyaluronan-functionalized bovine serum albumin nanoparticulate assembly for metastatic melanoma treatment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cations; Cell Movement; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Hyaluronic Acid; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Particle Size; Serum Albumin, Bovine; Surface Properties; Tumor Cells, Cultured | 2020 |
Upregulation of TRPC6 Mediated by PAX6 Hypomethylation Is Involved in the Mechanical Allodynia Induced by Chemotherapeutics in Dorsal Root Ganglion.
Topics: Animals; Antineoplastic Agents; Bortezomib; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Ganglia, Spinal; Gene Expression; Hyperalgesia; Male; Neuralgia; Oxaliplatin; Paclitaxel; PAX6 Transcription Factor; Rats; Rats, Sprague-Dawley; TRPC Cation Channels; Up-Regulation | 2020 |
Liuwei Dihuang pill suppresses metastasis by regulating the wnt pathway and disrupting -catenin/T cell factor interactions in a murine model of triple-negative breast cancer.
Topics: Animals; beta Catenin; Blotting, Western; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fluorescent Antibody Technique; Immunoprecipitation; Mice; Paclitaxel; TCF Transcription Factors; Triple Negative Breast Neoplasms; Wnt Signaling Pathway | 2019 |
Neurofilament light chain: a specific serum biomarker of axonal damage severity in rat models of Chemotherapy-Induced Peripheral Neurotoxicity.
Topics: Animals; Antineoplastic Agents; Axons; Biomarkers; Cisplatin; Disease Models, Animal; Female; Neurofilament Proteins; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nerves; Peripheral Nervous System Diseases; Rats, Wistar; Severity of Illness Index; Up-Regulation | 2020 |
Knockdown of A-kinase anchor protein 4 inhibits proliferation of triple-negative breast cancer cells
Topics: A Kinase Anchor Proteins; Animals; Apoptosis; Biomarkers; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Gene Knockdown Techniques; Gene Silencing; Humans; Immunophenotyping; Mice; Oxidative Stress; Paclitaxel; Reactive Oxygen Species; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2020 |
Paclitaxel Induces Immunogenic Cell Death in Ovarian Cancer via TLR4/IKK2/SNARE-Dependent Exocytosis.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Cancer Vaccines; Cell Line, Tumor; Disease Models, Animal; Exocytosis; Female; Humans; I-kappa B Kinase; Immunogenic Cell Death; Mice; Mice, Inbred C57BL; Middle Aged; Ovarian Neoplasms; Paclitaxel; Signal Transduction; SNARE Proteins; Toll-Like Receptor 4 | 2020 |
Eribulin Regresses a Cisplatinum-resistant Rare-type Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft Mouse Model.
Topics: Animals; Biomarkers, Tumor; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Furans; Humans; Ketones; Mice; Paclitaxel; Treatment Outcome; Triple Negative Breast Neoplasms; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Local Sympathectomy Promotes Anti-inflammatory Responses and Relief of Paclitaxel-induced Mechanical and Cold Allodynia in Mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cold Temperature; Disease Models, Animal; Female; Hyperalgesia; Inflammation; Male; Mice; Paclitaxel; Sympathectomy | 2020 |
Losartan attenuates neuroinflammation and neuropathic pain in paclitaxel-induced peripheral neuropathy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ganglia, Spinal; Losartan; Macrophages; Male; Neuralgia; Paclitaxel; Pain Management; Rats | 2020 |
A Chemotherapy-Induced Peripheral Neuropathy Model in Drosophila melanogaster.
Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents; Axons; Dendrites; Disease Models, Animal; Dissection; Drosophila melanogaster; Female; Genotype; Larva; Male; Microscopy, Fluorescence; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases | 2020 |
PPARγ activation mitigates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of Nrf2/HO-1 signaling pathway.
Topics: Analgesics; Animals; Disease Models, Animal; Heme Oxygenase (Decyclizing); Hyperalgesia; Male; Neuralgia; NF-E2-Related Factor 2; Paclitaxel; Pain Perception; Pain Threshold; PPAR gamma; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Spinal Cord; Up-Regulation | 2020 |
Paclitaxel Induces Upregulation of Transient Receptor Potential Vanilloid 1 Expression in the Rat Spinal Cord.
Topics: Acrylamides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Paclitaxel; Rats; RNA, Small Interfering; Spinal Cord; TRPV Cation Channels; Up-Regulation | 2020 |
Monosialoganglioside GM1 reduces toxicity of Ptx and increase anti-metastasic effect in a murine mammary cancer model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Gangliosides; Male; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Polyethylene Glycols | 2020 |
JTC-801 alleviates mechanical allodynia in paclitaxel-induced neuropathic pain through the PI3K/Akt pathway.
Topics: Aminoquinolines; Analgesics; Animals; Behavior, Animal; Benzamides; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Inflammation Mediators; Interleukin-1beta; Male; Narcotic Antagonists; Neuralgia; Nociceptin Receptor; Paclitaxel; Pain Threshold; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Receptors, Opioid; Signal Transduction; Tumor Necrosis Factor-alpha | 2020 |
Peripheral deficiency and antiallodynic effects of 2-arachidonoyl glycerol in a mouse model of paclitaxel-induced neuropathic pain.
Topics: Analgesics; Animals; Arachidonic Acids; Benzodioxoles; Cannabinoid Receptor Agonists; Disease Models, Animal; Endocannabinoids; Enzyme Inhibitors; Female; Glycerides; Hyperalgesia; Mice, Inbred BALB C; Monoacylglycerol Lipases; Neuralgia; Paclitaxel; Piperidines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Skin | 2020 |
Novel monoclonal antibody against integrin α3 shows therapeutic potential for ovarian cancer.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Carboplatin; Carcinoma; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Female; HCT116 Cells; Human Umbilical Vein Endothelial Cells; Humans; Integrin alpha3; Mice; Mice, Inbred BALB C; Neoplasm Recurrence, Local; Ovarian Neoplasms; Paclitaxel; Prognosis; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2020 |
LINC00160 mediated paclitaxel-And doxorubicin-resistance in breast cancer cells by regulating TFF3 via transcription factor C/EBPβ.
Topics: Adult; Animals; Biomarkers, Tumor; Breast Neoplasms; CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mice; Middle Aged; Paclitaxel; Prognosis; RNA Interference; RNA, Long Noncoding; Transcription Factors; Trefoil Factor-3; Xenograft Model Antitumor Assays | 2020 |
Nanomicelle protects the immune activation effects of Paclitaxel and sensitizes tumors to anti-PD-1 Immunotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Endoplasmic Reticulum Stress; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Immunogenic Cell Death; Immunotherapy; Mice; Micelles; Nanoparticles; Neoplasms; Paclitaxel; Programmed Cell Death 1 Receptor; Tumor Microenvironment | 2020 |
Circadian regulation of chemotherapy-induced peripheral neuropathic pain and the underlying transcriptomic landscape.
Topics: Animals; Antineoplastic Agents, Phytogenic; ARNTL Transcription Factors; Circadian Rhythm; Disease Models, Animal; Ganglia, Spinal; Gene Expression; In Vitro Techniques; Mice; Neuralgia; Paclitaxel; Period Circadian Proteins; Peripheral Nerve Injuries; Rats; Spinal Cord Dorsal Horn | 2020 |
Safety, pharmacokinetics and tissue penetration of PIPAC paclitaxel in a swine model.
Topics: Animals; Biopsy; Disease Models, Animal; Female; Hyperthermic Intraperitoneal Chemotherapy; Paclitaxel; Peritoneal Neoplasms; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine | 2021 |
Iridoids isolated from Viticis Fructus inhibit paclitaxel-induced mechanical allodynia in mice.
Topics: Animals; Disease Models, Animal; Drug Interactions; Hyperalgesia; Iridoids; Male; Mice; Mice, Inbred C57BL; Paclitaxel; Plant Extracts; Vitex | 2021 |
Design, manufacture and initial tests of a drug-eluting coronary stent.
Topics: Animals; Disease Models, Animal; Drug-Eluting Stents; Female; Follow-Up Studies; Male; Microscopy; Paclitaxel; Prosthesis Design; Rabbits; Sirolimus; Spectrophotometry, Infrared; Swine | 2020 |
Umbelliprenin relieves paclitaxel-induced neuropathy.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Interleukin-6; Lipid Peroxidation; Male; Mice; Oxidative Stress; Paclitaxel; Pain Threshold; Sciatic Nerve; Sciatic Neuropathy; Umbelliferones | 2020 |
PINK1 alleviates thermal hypersensitivity in a paclitaxel-induced Drosophila model of peripheral neuropathy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drosophila; Drosophila Proteins; Gene Expression; Gene Knockdown Techniques; Hyperalgesia; Hyperesthesia; Paclitaxel; Peripheral Nervous System Diseases; Protein Serine-Threonine Kinases; Sensory Receptor Cells | 2020 |
Transient impact of paclitaxel on mouse fertility and protective effect of gonadotropin‑releasing hormone agonist.
Topics: Animals; Disease Models, Animal; Female; Fertility; Fertility Preservation; Gonadotropin-Releasing Hormone; Humans; Mice; Mice, Inbred ICR; Neoplasms; Ovarian Follicle; Ovulation Induction; Paclitaxel; Primary Ovarian Insufficiency | 2020 |
CREB Participates in Paclitaxel-Induced Neuropathic Pain Genesis Through Transcriptional Activation of Dnmt3a in Primary Sensory Neurons.
Topics: Animals; Blotting, Western; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; DNA Methyltransferase 3A; Fluorescent Antibody Technique; Ganglia, Spinal; Male; Mice; Neuralgia; Paclitaxel; Sensory Receptor Cells; Transcriptional Activation; Up-Regulation | 2021 |
Local Targeting of Lung-Tumor-Associated Macrophages with Pulmonary Delivery of a CSF-1R Inhibitor for the Treatment of Breast Cancer Lung Metastases.
Topics: Administration, Inhalation; Administration, Intravenous; Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Lung Neoplasms; Mice; Paclitaxel; Phosphorylation; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Tumor Microenvironment; Tumor-Associated Macrophages | 2020 |
Deficit in voluntary wheel running in chronic inflammatory and neuropathic pain models in mice: Impact of sex and genotype.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Phytogenic; Chronic Pain; Disease Models, Animal; Female; Freund's Adjuvant; Genotype; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Neuralgia; Nociceptive Pain; Paclitaxel; Peripheral Nerve Injuries; Running; Sex Factors | 2021 |
Involvement of TACAN, a Mechanotransducing Ion Channel, in Inflammatory But Not Neuropathic Hyperalgesia in the Rat.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Inflammation; Ion Channels; Male; Mechanotransduction, Cellular; Neuralgia; Oxaliplatin; Paclitaxel; Pain Threshold; Rats; Rats, Sprague-Dawley | 2021 |
Depletion and Maturation of Myeloid-Derived Suppressor Cells in Murine Cancer Models.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Differentiation; Disease Models, Animal; Mice, Inbred C57BL; Mice, Transgenic; Myeloid-Derived Suppressor Cells; Neoplasms; Paclitaxel; Tretinoin | 2021 |
Human Intravenous Immunoglobulin Alleviates Neuropathic Symptoms in a Rat Model of Paclitaxel-Induced Peripheral Neurotoxicity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Axons; Biomarkers; Disease Models, Animal; Disease Susceptibility; Humans; Hyperalgesia; Immunoglobulins, Intravenous; Macrophages; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nervous System Diseases; Rats; Treatment Outcome | 2021 |
Analgesic Effects of Sokeikakketsuto on Chemotherapy-Induced Mechanical Allodynia and Cold Hyperalgesia in Rats.
Topics: Analgesics; Animals; Antineoplastic Agents; Bortezomib; Cold Temperature; Disease Models, Animal; Drugs, Chinese Herbal; Duloxetine Hydrochloride; Humans; Hyperalgesia; Male; Medicine, Kampo; Oxaliplatin; Paclitaxel; Pain Measurement; Rats; Rats, Sprague-Dawley | 2021 |
Pronociceptive Roles of Schwann Cell-Derived Galectin-3 in Taxane-Induced Peripheral Neuropathy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Proteins; Cell Movement; Chemotaxis; Clodronic Acid; Disease Models, Animal; Docetaxel; Female; Galectins; Humans; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Paclitaxel; Pain Perception; Peripheral Nervous System Diseases; Prospective Studies; Rats; Schwann Cells; Sciatic Nerve; Up-Regulation | 2021 |
Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cytoskeleton; Disease Models, Animal; Excitation Contraction Coupling; Female; Genetic Predisposition to Disease; Heart Conduction System; Heart Rate; Lamin Type A; Male; Mice, Mutant Strains; Mutation; Myocytes, Cardiac; Paclitaxel; Progeria; Refractory Period, Electrophysiological; Swine; Swine, Miniature; Tubulin | 2022 |
Lyophilization Serves as an Effective Strategy for Drug Development of the α9α10 Nicotinic Acetylcholine Receptor Antagonist α-Conotoxin GeXIVA[1,2].
Topics: Acute Pain; Analgesics; Animals; Conotoxins; Disease Models, Animal; Drug Development; Freeze Drying; Male; Neuralgia; Nicotinic Antagonists; Paclitaxel; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2021 |
Chemotherapeutic Agent-Induced Vulvodynia, an Experimental Model.
Topics: Analgesics; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Female; Gabapentin; Neuralgia; Paclitaxel; Pain Measurement; Rats; Rats, Sprague-Dawley; Vulvodynia | 2021 |
Protective effects of paclitaxel on thioacetamide-induced liver fibrosis in a rat model.
Topics: Animals; Disease Models, Animal; Liver Cirrhosis; Male; Paclitaxel; Rats; Rats, Sprague-Dawley; Thioacetamide | 2021 |
Oral recombinant methioninase combined with paclitaxel arrests recalcitrant ovarian clear cell carcinoma growth in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carbon-Sulfur Lyases; Carcinoma; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Heterografts; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Recombinant Proteins; Sarcoma, Clear Cell; Tumor Burden; Xenograft Model Antitumor Assays | 2021 |
Decursin Alleviates Mechanical Allodynia in a Paclitaxel-Induced Neuropathic Pain Mouse Model.
Topics: Animals; Benzopyrans; Butyrates; Disease Models, Animal; Enzyme Activators; Humans; Hyperalgesia; Mice; Neuralgia; Paclitaxel | 2021 |
Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Carriers; Female; Fluorescent Dyes; Humans; Intravital Microscopy; Mice; Molecular Imaging; Molecular Probes; Nanoparticles; Neoplasms; Optical Imaging; Paclitaxel; Patient Selection; Reproducibility of Results; Theranostic Nanomedicine; Tissue Distribution; Tumor Microenvironment | 2021 |
Phenylboronic acid modified nanoparticles simultaneously target pancreatic cancer and its metastasis and alleviate immunosuppression.
Topics: Animals; Boronic Acids; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Human Umbilical Vein Endothelial Cells; Humans; Male; Membrane Glycoproteins; Mice; Myeloid-Derived Suppressor Cells; Nanoparticles; Paclitaxel; Pancreatic Neoplasms; Tumor Escape; Tumor Microenvironment | 2021 |
Systemic metastasis-targeted nanotherapeutic reinforces tumor surgical resection and chemotherapy.
Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chemotherapy, Adjuvant; Disease Models, Animal; Drug Carriers; Epithelial-Mesenchymal Transition; Female; Heparin, Low-Molecular-Weight; Human Umbilical Vein Endothelial Cells; Humans; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Nanoparticles; Neoplasm Metastasis; Neoplastic Cells, Circulating; Paclitaxel; Proof of Concept Study; Rats; Stilbenes; Theranostic Nanomedicine | 2021 |
Pharmacological rescue of cognitive function in a mouse model of chemobrain.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chemotherapy-Related Cognitive Impairment; Cognition; Disease Models, Animal; Female; Inositol 1,4,5-Trisphosphate Receptors; Lithium Chloride; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Paclitaxel | 2021 |
Vimentin Promotes the Aggressiveness of Triple Negative Breast Cancer Cells Surviving Chemotherapeutic Treatment.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cyclophosphamide; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Therapy; Epirubicin; Epithelial-Mesenchymal Transition; Female; Humans; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Paclitaxel; Triple Negative Breast Neoplasms; Vimentin; Zebrafish | 2021 |
Comparative colloidal stability, antitumor efficacy, and immunosuppressive effect of commercial paclitaxel nanoformulations.
Topics: Albumins; Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Emulsions; Female; Immunosuppressive Agents; Immunotherapy; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Nanomedicine; Nanoparticles; Paclitaxel; Triple Negative Breast Neoplasms | 2021 |
Intranasal Paclitaxel Alters Alzheimer's Disease Phenotypic Features in 3xTg-AD Mice.
Topics: Administration, Intranasal; Alzheimer Disease; Animals; Antineoplastic Agents, Phytogenic; Axonal Transport; Blood-Brain Barrier; Brain; Disease Models, Animal; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Transgenic; Morris Water Maze Test; Neurons; Paclitaxel | 2021 |
Akt targeting as a strategy to boost chemotherapy efficacy in non-small cell lung cancer through metabolism suppression.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Culture Techniques; Cell Cycle Checkpoints; Cell Line, Tumor; Disease Models, Animal; Energy Metabolism; Glycolysis; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Mice; Mitochondria; Paclitaxel; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays | 2017 |
Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Eosinophils; Escape Reaction; Female; Hyperalgesia; Leukocyte Count; Locomotion; NAD; Neutrophils; Niacinamide; Nociception; Paclitaxel; Pain Measurement; Peripheral Nervous System Diseases; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Time Factors | 2017 |
Influence of Drugs Carried in Lipid Nanoparticles in Coronary Disease of Rabbit Transplanted Heart.
Topics: Animals; Antineoplastic Agents, Phytogenic; Coronary Artery Disease; Cytokines; Disease Models, Animal; Drug Carriers; Gene Expression Regulation; Graft Rejection; Graft Survival; Heart Transplantation; Immunohistochemistry; Immunosuppressive Agents; Injections, Intravenous; Methotrexate; Myocardium; Nanoparticles; Paclitaxel; Rabbits; Real-Time Polymerase Chain Reaction; RNA | 2017 |
Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy.
Topics: Alopecia; Animals; Antineoplastic Agents, Phytogenic; Calcium; Cell Line, Tumor; Disease Models, Animal; Ganglia, Spinal; Humans; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Minoxidil; Neoplasms; Neurites; Neuroprotective Agents; Paclitaxel; Peripheral Nervous System Diseases; Sciatic Nerve | 2017 |
Targeting Smoothened Sensitizes Gastric Cancer to Chemotherapy in Experimental Models.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; Male; Mice, Inbred C57BL; Paclitaxel; Smoothened Receptor; Stomach Neoplasms | 2017 |
Antibody-targeted paclitaxel loaded nanoparticles for the treatment of CD20
Topics: Animals; Antigens, CD20; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Humans; Lymphoma, B-Cell; Mice; Molecular Targeted Therapy; Nanoparticles; Paclitaxel; Rituximab; Treatment Outcome | 2017 |
Oral cancer cells sustainedly infected with Porphyromonas gingivalis exhibit resistance to Taxol and have higher metastatic potential.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bacteroidaceae Infections; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression; Humans; Male; Mice; Mouth Neoplasms; Neoplasm Metastasis; Paclitaxel; Porphyromonas gingivalis; Receptor, Notch1; Xenograft Model Antitumor Assays | 2017 |
Microtubule-Targeting Agents Eribulin and Paclitaxel Differentially Affect Neuronal Cell Bodies in Chemotherapy-Induced Peripheral Neuropathy.
Topics: Activating Transcription Factor 3; Animals; Antineoplastic Agents; Cell Body; Disease Models, Animal; Female; Furans; Ganglia, Spinal; Ketones; Mice; Mice, Inbred BALB C; Microtubules; Paclitaxel; Sciatic Neuropathy; Sensory Receptor Cells; Tubulin | 2017 |
Paclitaxel synergizes with exposure time adjusted CD22-targeting immunotoxins against B-cell malignancies.
Topics: Animals; Antineoplastic Agents; Bacterial Toxins; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Exotoxins; Humans; Immunotoxins; Mice; Paclitaxel; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Sialic Acid Binding Ig-like Lectin 2; Treatment Outcome; Xenograft Model Antitumor Assays | 2017 |
Kanglaite sensitizes colorectal cancer cells to Taxol via NF-κΒ inhibition and connexin 43 upregulation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colorectal Neoplasms; Connexin 43; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Mice, Inbred BALB C; NF-kappa B; Paclitaxel; Treatment Outcome; Up-Regulation | 2017 |
Taxol alleviates collagen-induced arthritis in mice by inhibiting the formation of microvessels.
Topics: Animals; Arthritis, Experimental; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microvessels; Neovascularization, Pathologic; Paclitaxel; Synovial Membrane; Vascular Endothelial Growth Factor A | 2019 |
Deletion of Sarm1 gene is neuroprotective in two models of peripheral neuropathy.
Topics: Action Potentials; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Armadillo Domain Proteins; Cytoskeletal Proteins; Diet, High-Fat; Disease Models, Animal; Hyperalgesia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Conduction; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Reaction Time; Sural Nerve | 2017 |
Impact of Fluoropolymer-Based Paclitaxel Delivery on Neointimal Proliferation and Vascular Healing: A Comparative Peripheral Drug-Eluting Stent Study in the Familial Hypercholesterolemic Swine Model of Femoral Restenosis.
Topics: Angiography; Animals; Cardiovascular Agents; Cell Proliferation; Constriction, Pathologic; Disease Models, Animal; Drug-Eluting Stents; Endovascular Procedures; Femoral Artery; Hyperlipoproteinemia Type II; Methacrylates; Neointima; Paclitaxel; Peripheral Arterial Disease; Polymers; Polyvinyls; Prosthesis Design; Recurrence; Sus scrofa; Time Factors; Tomography, Optical Coherence; Vascular Patency; Wound Healing | 2017 |
Protein kinase C inhibitor chelerythrine selectively inhibits proliferation of triple-negative breast cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Isoenzymes; Mice; Paclitaxel; Protein Kinase C; Protein Kinase Inhibitors; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2017 |
Single and combined effects of Δ
Topics: Analgesics; Animals; Antineoplastic Agents, Phytogenic; Cannabidiol; Disease Models, Animal; Dronabinol; Drug Therapy, Combination; Hyperalgesia; Male; Mice, Inbred C57BL; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Vincristine | 2017 |
Combination of paclitaxel, bevacizumab and MEK162 in second line treatment in platinum-relapsing patient derived ovarian cancer xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bevacizumab; Biomarkers; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Humans; Mice; Mutation; Ovarian Neoplasms; Paclitaxel; Platinum; Recurrence; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Free paclitaxel-loaded E-selectin binding peptide modified micelle self-assembled from hyaluronic acid-paclitaxel conjugate inhibit breast cancer metastasis in a murine model.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; E-Selectin; Humans; Hyaluronic Acid; Mice; Micelles; Neoplasm Metastasis; Paclitaxel; Peptides; Polyethylene Glycols | 2017 |
Involvement of Charcot-Marie-Tooth disease gene mitofusin 2 expression in paclitaxel-induced mechanical allodynia in rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Charcot-Marie-Tooth Disease; Disease Models, Animal; GTP Phosphohydrolases; Hyperalgesia; Male; Membrane Proteins; Mitochondrial Proteins; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley | 2017 |
Morin promotes prostate cancer cells chemosensitivity to paclitaxel through miR-155/GATA3 axis.
Topics: 3' Untranslated Regions; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Cluster Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Flavonoids; GATA3 Transcription Factor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Mice; MicroRNAs; Paclitaxel; Prostatic Neoplasms; RNA Interference; Xenograft Model Antitumor Assays | 2017 |
Therapeutic utility of natural estrogen receptor beta agonists on ovarian cancer.
Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Biological Products; Cell Line, Tumor; Cell Movement; Cell Survival; Cisplatin; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Estrogen Receptor beta; Estrogens; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; NF-kappa B; Ovarian Neoplasms; Paclitaxel; Signal Transduction; Xenograft Model Antitumor Assays | 2017 |
Antiallodynic effect of β-caryophyllene on paclitaxel-induced peripheral neuropathy in mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Cannabinoid Receptor Modulators; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Indoles; Male; Neuralgia; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Piperidines; Polycyclic Sesquiterpenes; Pyrazoles; Random Allocation; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sesquiterpenes; Spinal Cord | 2017 |
Therapeutic potential of certain drug combinations on paclitaxel-induced peripheral neuropathy in rats.
Topics: Animals; Disease Models, Animal; Drug Combinations; Male; Neuralgia; Paclitaxel; Rats; Rats, Wistar | 2017 |
Rapid
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Disease Models, Animal; Drug Therapy, Combination; Epirubicin; Gliosarcoma; Humans; Hydrogels; Infusion Pumps, Implantable; Magnetic Resonance Imaging; Mice; Neoplasm, Residual; Paclitaxel; Secondary Prevention; Survival Analysis; Treatment Outcome; Tumor Cells, Cultured | 2017 |
The anti-cancer effects of itraconazole in epithelial ovarian cancer.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ovarian Epithelial; Cell Proliferation; Disease Models, Animal; Drug Synergism; Endothelial Cells; Female; Heterografts; Itraconazole; Mice; Neoplasm Transplantation; Paclitaxel; Treatment Outcome | 2017 |
Paclitaxel Promotes Cell Apoptosis in Uterine Leiomyomas.
Topics: Animals; Apoptosis; Disease Models, Animal; Female; Leiomyoma; Mice; Mice, Inbred C57BL; Paclitaxel; Uterus | 2017 |
Effects of a water extract of Lepidium meyenii root in different models of persistent pain in rats.
Topics: Administration, Oral; Analgesics; Animals; Chronic Pain; Disease Models, Animal; Hyperalgesia; Injections, Intra-Articular; Iodoacetic Acid; Male; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Palmitic Acids; Phytotherapy; Plant Extracts; Plant Roots; Polyunsaturated Alkamides; Postural Balance; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sciatica; Water | 2017 |
Gene Expression Profiling of Cutaneous Injured and Non-Injured Nociceptors in SNI Animal Model of Neuropathic Pain.
Topics: Animals; Biopsy; Caspase 6; Computational Biology; Disease Models, Animal; Ganglia, Spinal; Gene Expression Profiling; Humans; Immunohistochemistry; Mice; Mice, Knockout; Neuralgia; Nociceptors; Paclitaxel; Rats; Skin; Spinal Nerves; Transcriptome | 2017 |
Co-delivery of paclitaxel and cetuximab by nanodiamond enhances mitotic catastrophe and tumor inhibition.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cetuximab; Colorectal Neoplasms; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; ErbB Receptors; Gene Expression; Humans; Mitosis; Nanodiamonds; Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays | 2017 |
Combination Cancer Therapy Using Chimeric Antigen Receptor-Engineered Natural Killer Cells as Drug Carriers.
Topics: Animals; Antigens, CD19; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cytotoxicity, Immunologic; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Gene Expression; Humans; Immunotherapy; Killer Cells, Natural; Liposomes; Mice; Mice, Knockout; Nanomedicine; Nanoparticles; Neoplasms; Paclitaxel; Receptor, ErbB-2; Receptors, Antigen; Recombinant Fusion Proteins; Treatment Outcome; Xenograft Model Antitumor Assays | 2017 |
YAP transcriptionally regulates COX-2 expression and GCCSysm-4 (G-4), a dual YAP/COX-2 inhibitor, overcomes drug resistance in colorectal cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Binding Sites; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Genes, Reporter; Humans; Male; Mice; Nuclear Proteins; Paclitaxel; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Transport; Response Elements; Transcription Factors; Transcriptional Activation; Xenograft Model Antitumor Assays | 2017 |
Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Hyperalgesia; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Nicotine; Paclitaxel; Peripheral Nervous System Diseases; Receptors, Cholinergic; Taxoids | 2018 |
Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Carbazoles; Disease Models, Animal; Enzyme Activators; Histocytochemistry; Neuroprotective Agents; Nicotinamide Phosphoribosyltransferase; Paclitaxel; Peripheral Nervous System Diseases; Rats; Treatment Outcome | 2017 |
Effects of WD‑3 on tumor growth and the expression of integrin αvβ3 and ERK1/2 in mice bearing human gastric cancer using the 18F‑RGD PET/CT imaging system.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Fluorodeoxyglucose F18; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaVbeta3; MAP Kinase Signaling System; Medicine, Chinese Traditional; Mice; Paclitaxel; Positron Emission Tomography Computed Tomography; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2017 |
Paclitaxel alleviated liver injury of septic mice by alleviating inflammatory response via microRNA-27a/TAB3/NF-κB signaling pathway.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred C57BL; MicroRNAs; NF-kappa B; Oxidative Stress; Paclitaxel; RNA, Messenger; Sepsis; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Evaluation Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus in Combination With Anticancer Drugs in Human Cancer Orthotopic Mouse Models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Fucus; Humans; MCF-7 Cells; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Polysaccharides; Tamoxifen; Undaria | 2018 |
Preclinical evaluation of a paclitaxel-incorporated nanoparticle-coated balloon in rabbit and porcine models.
Topics: Animals; Cardiac Catheterization; Cardiac Catheters; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Dimethylpolysiloxanes; Disease Models, Animal; Drug Carriers; Endothelial Cells; Female; Iliac Artery; Male; Materials Testing; Myocytes, Smooth Muscle; Nanoparticles; Paclitaxel; Percutaneous Coronary Intervention; Prosthesis Design; Rabbits; Sus scrofa; Time Factors; Tomography, Optical Coherence | 2018 |
Novel multi‑kinase inhibitor, T03 inhibits Taxol‑resistant breast cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Humans; Mice; Paclitaxel; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; raf Kinases; Signal Transduction; Xenograft Model Antitumor Assays | 2018 |
Structure Reconstruction of LyP-1:
Topics: Amides; Animals; Antineoplastic Agents, Phytogenic; Brain; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Female; Humans; Lymphatic Vessels; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Mitochondrial Proteins; Molecular Docking Simulation; Paclitaxel; Peptides, Cyclic; Polyethylene Glycols; Rats; Stereoisomerism | 2018 |
Blocking of cytokines signalling attenuates evoked and spontaneous neuropathic pain behaviours in the paclitaxel rat model of chemotherapy-induced neuropathy.
Topics: Animals; Cytokines; Disease Models, Animal; Etanercept; Interleukin 1 Receptor Antagonist Protein; Male; Neuralgia; Paclitaxel; Rats; Rats, Wistar; Signal Transduction; Up-Regulation | 2018 |
Additional dexamethasone in chemotherapies with carboplatin and paclitaxel could reduce the impaired glycometabolism in rat models.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Carboplatin; Dexamethasone; Disease Models, Animal; Female; Glucagon; Humans; Hyperglycemia; Insulin; Ovarian Neoplasms; Paclitaxel; Rats | 2018 |
Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy.
Topics: Animals; Antineoplastic Agents; Astrocytes; Disease Models, Animal; Female; Ganglia, Spinal; Guanine Nucleotide Exchange Factors; Hydrazones; Hyperalgesia; Isoxazoles; Male; Mice; Mice, Knockout; Nerve Fibers; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Spinal Cord | 2018 |
Evaluation of the Distribution of Paclitaxel After Application of a Paclitaxel-Coated Balloon in the Rabbit Urethra.
Topics: Animals; Catheterization; Constriction, Pathologic; Disease Models, Animal; Drug Delivery Systems; Male; Paclitaxel; Rabbits; Tubulin Modulators; Urethra; Urethral Stricture; Urothelium | 2018 |
Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain.
Topics: Amines; Analgesics; Animals; Antineoplastic Agents; Blood Pressure; Cyclohexanecarboxylic Acids; Disease Models, Animal; Fluorobenzenes; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Locomotion; Male; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Peripheral Nervous System; Rats; Rats, Sprague-Dawley | 2018 |
Modulation by hydroxytyrosol of oxidative stress and antitumor activities of paclitaxel in breast cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Female; Oxidative Stress; Paclitaxel; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome; Tumor Burden | 2019 |
Development and evaluation of novel tumor-targeting paclitaxel-loaded nano-carriers for ovarian cancer treatment: in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Liberation; Female; Humans; Mice; Molecular Targeted Therapy; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Polyethylene Glycols; Theranostic Nanomedicine; Xenograft Model Antitumor Assays | 2018 |
Linear Micro-patterned Drug Eluting Balloon (LMDEB) for Enhanced Endovascular Drug Delivery.
Topics: Angioplasty, Balloon, Coronary; Animals; Atherosclerosis; Chromatography, Liquid; Coronary Angiography; Coronary Restenosis; Disease Models, Animal; Drug Delivery Systems; Drug-Eluting Stents; Iliac Artery; Male; Mass Spectrometry; Microscopy, Confocal; Microscopy, Fluorescence; Paclitaxel; Percutaneous Coronary Intervention; Pressure; Rabbits; Swine; Swine, Miniature; Treatment Outcome | 2018 |
A paclitaxel prodrug with bifunctional folate and albumin binding moieties for both passive and active targeted cancer therapy.
Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Therapy; Flow Cytometry; Folic Acid; Heterografts; Humans; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Models, Biological; Molecular Targeted Therapy; Neoplasm Transplantation; Paclitaxel; Prodrugs; Protein Binding; Treatment Outcome; Tumor Protein, Translationally-Controlled 1 | 2018 |
Cognitive impairment in a rat model of neuropathic pain: role of hippocampal microtubule stability.
Topics: Animals; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Learning; Long-Term Potentiation; Male; Memory; Microtubules; Neuralgia; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Tubulin Modulators | 2018 |
Pegylated liposomal‑paclitaxel induces ovarian cancer cell apoptosis via TNF‑induced ERK/AKT signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Liposomes; Male; Mice; Paclitaxel; Polyethylene Glycols; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays | 2018 |
[Anti-prostate cancer effect of roemerine: An experimental study].
Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Drugs, Chinese Herbal; Male; Mice; Mice, Nude; Paclitaxel; Prostatic Neoplasms | 2017 |
Treatment of pancreatic ductal adenocarcinoma with tumor antigen specific-targeted delivery of paclitaxel loaded PLGA nanoparticles.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents, Immunological; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Liberation; Endocytosis; Female; Gene Expression; Humans; Mice; Molecular Targeted Therapy; Mucin-1; Nanoparticles; Paclitaxel; Pancreatic Neoplasms; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Xenograft Model Antitumor Assays | 2018 |
Combination therapy involving radiofrequency ablation and targeted chemotherapy with bevacizumab plus paclitaxel and cisplatin in a rabbit VX2 lung tumor model.
Topics: Animals; Antineoplastic Agents; Bevacizumab; Carcinoma; Catheter Ablation; Cell Line, Tumor; Cisplatin; Combined Modality Therapy; Disease Models, Animal; Drug Therapy, Combination; Female; Lung Neoplasms; Paclitaxel; Rabbits | 2018 |
Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy.
Topics: Animals; Complement System Proteins; Disease Models, Animal; Hyperalgesia; Immunity, Innate; Nerve Fibers; Neuralgia; Paclitaxel; Peripheral Nervous System Diseases; Quality of Life; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 2018 |
Nmnat mitigates sensory dysfunction in a
Topics: Animals; Cell Count; Dendrites; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Female; Larva; Male; Microtubules; Nicotinamide-Nucleotide Adenylyltransferase; Nociception; Paclitaxel; Peripheral Nervous System Diseases; Sensory Receptor Cells | 2018 |
Regression of Atherosclerotic Plaques of Cholesterol-Fed Rabbits by Combined Chemotherapy With Paclitaxel and Methotrexate Carried in Lipid Core Nanoparticles.
Topics: Animals; Aorta; Aortic Diseases; Atherosclerosis; Cardiovascular Agents; Cholesterol, Dietary; Cytokines; Disease Models, Animal; Drug Compounding; Drug Therapy, Combination; Inflammation Mediators; Lipids; Liposomes; Male; Matrix Metalloproteinase 9; Methotrexate; Nanoparticles; Paclitaxel; Plaque, Atherosclerotic; Rabbits | 2018 |
Identification of cardioprotective drugs by medium-scale
Topics: Actins; Animals; Cardiotonic Agents; Disease Models, Animal; Drosophila melanogaster; Drug Evaluation, Preclinical; Frataxin; Friedreich Ataxia; Iron-Binding Proteins; Methylene Blue; Microtubules; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Myosins; Paclitaxel; Reproducibility of Results; Sarcomeres; Small Molecule Libraries | 2018 |
The Effect of the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid and Paclitaxel Treatment on Full-Thickness Wound Healing in Mice.
Topics: Animals; Back Injuries; Disease Models, Animal; Histone Deacetylase Inhibitors; Mice; Mice, Nude; Paclitaxel; Vorinostat; Wound Healing | 2018 |
Mechanisms of enhanced antiglioma efficacy of polysorbate 80-modified paclitaxel-loaded PLGA nanoparticles by focused ultrasound.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apolipoproteins E; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain Neoplasms; Disease Models, Animal; Drug Compounding; Drug Delivery Systems; Drug Liberation; Extracorporeal Shockwave Therapy; Female; Gene Expression; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Polysorbates; Survival Analysis; Tight Junctions | 2018 |
Evoked and Ongoing Pain-Like Behaviours in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Hyperalgesia; Male; Motor Activity; Neuralgia; Paclitaxel; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Psychomotor Performance; Random Allocation; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors | 2018 |
Differential Morphological and Biochemical Recovery from Chemotherapy-Induced Peripheral Neuropathy Following Paclitaxel, Ixabepilone, or Eribulin Treatment in Mouse Sciatic Nerves.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Epothilones; Female; Furans; Intermediate Filaments; Ketones; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Myelin Sheath; Paclitaxel; Recovery of Function; S100 Proteins; Schwann Cells; Sciatic Neuropathy; Time Factors; Tubulin | 2018 |
A novel approach to monitoring the efficacy of anti-tumor treatments in animal models: combining functional MRI and texture analysis.
Topics: Allografts; Animals; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Contrast Media; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Animal; Mice; Paclitaxel; Treatment Outcome | 2018 |
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Calcium Channels, N-Type; Calcium Channels, T-Type; CHO Cells; Cricetulus; Diprenorphine; Disease Models, Animal; Female; Ganglia, Spinal; HIV Infections; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Neuralgia; Neurons; Paclitaxel; Pentacyclic Triterpenes; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Triterpenes; Tritium | 2019 |
Beneficial effects of Gelsemium-based treatment against paclitaxel-induced painful symptoms.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dose-Response Relationship, Drug; Gelsemium; Hyperalgesia; Male; Paclitaxel; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Plant Extracts; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2018 |
Paclitaxel-coated stents to prevent hyperplastic proliferation of ureteral tissue: from in vitro to in vivo.
Topics: Animals; Cell Line; Cell Proliferation; Disease Models, Animal; Drug-Eluting Stents; Epithelial Cells; Humans; Hyperplasia; Male; Paclitaxel; Rats; Ureter; Ureteral Obstruction; Urothelium | 2020 |
Monitoring Early Breast Cancer Response to Neoadjuvant Therapy Using H-Scan Ultrasound Imaging: Preliminary Preclinical Results.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease Models, Animal; Female; Mice; Mice, Nude; Neoadjuvant Therapy; Paclitaxel; Phantoms, Imaging; Treatment Outcome; Ultrasonography | 2019 |
In vivo metabolic and SHG imaging for monitoring of tumor response to chemotherapy.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor; Cisplatin; Collagen; Colorectal Neoplasms; Disease Models, Animal; Female; Irinotecan; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence, Multiphoton; NADP; Paclitaxel; Second Harmonic Generation Microscopy | 2019 |
Enhanced bioreduction-responsive diselenide-based dimeric prodrug nanoparticles for triple negative breast cancer therapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Heterografts; Humans; Mice, Nude; Models, Theoretical; Molecular Targeted Therapy; Nanoparticles; Neoplasm Transplantation; Oxidation-Reduction; Paclitaxel; Prodrugs; Selenium Compounds; Treatment Outcome; Triple Negative Breast Neoplasms | 2018 |
Monoclonal Antibody Targeting the Matrix Metalloproteinase 9 Prevents and Reverses Paclitaxel-Induced Peripheral Neuropathy in Mice.
Topics: Animals; Antibodies, Monoclonal; Cells, Cultured; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; Immunologic Factors; Male; Matrix Metalloproteinase 9; Mice; Neuralgia; Neurons; Neuroprotective Agents; Paclitaxel; Peripheral Nervous System Diseases | 2019 |
Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery.
Topics: Animals; Antineoplastic Agents; Biomarkers; Carcinoma, Pancreatic Ductal; Cell Line; Disease Models, Animal; Endothelium, Lymphatic; Female; Humans; Immunohistochemistry; Lymph Nodes; Male; Mice; Molecular Targeted Therapy; Nanoparticles; Neovascularization, Pathologic; Paclitaxel; Pancreatic Neoplasms; Theranostic Nanomedicine; Xenograft Model Antitumor Assays | 2018 |
Pre- and post-operative anti-PD-L1 plus anti-angiogenic therapies in mouse breast or renal cancer models of micro- or macro-metastatic disease.
Topics: Animals; B7-H1 Antigen; Bevacizumab; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Immunotherapy; Kidney Neoplasms; Mammary Neoplasms, Animal; Mice; Neoadjuvant Therapy; Neovascularization, Pathologic; Paclitaxel; Sunitinib | 2019 |
Mesenchymal stem cells therapy enhances the efficacy of pregabalin and prevents its motor impairment in paclitaxel-induced neuropathy in rats: Role of Notch1 receptor and JAK/STAT signaling pathway.
Topics: Acetone; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Caspase 3; Cell- and Tissue-Based Therapy; Disease Models, Animal; Hyperalgesia; Interleukin-6; Janus Kinases; Male; Mesenchymal Stem Cells; Motor Disorders; Nerve Growth Factor; Paclitaxel; Pregabalin; Rats; Rats, Wistar; Receptor, Notch1; Rotarod Performance Test; Sciatic Neuropathy; STAT Transcription Factors; Time Factors; Tumor Necrosis Factor-alpha | 2019 |
Targeting cancer stem cell signature gene SMOC-2 Overcomes chemoresistance and inhibits cell proliferation of endometrial carcinoma.
Topics: Animals; Biomarkers; Calcium-Binding Proteins; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Mice; Neoplasm Grading; Neoplasm Staging; Neoplastic Stem Cells; Paclitaxel; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2019 |
Stereocomplex micelle loaded with paclitaxel for enhanced therapy of breast cancer in an orthotopic mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Dextrans; Disease Models, Animal; Drug Carriers; Female; Humans; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Particle Size; Polyesters; Surface Properties; Tissue Distribution | 2019 |
The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.
Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Disease Models, Animal; Female; Gemcitabine; Humans; Mice; Mice, Nude; Middle Aged; Paclitaxel; Sarcoma; Treatment Outcome; Xenograft Model Antitumor Assays | 2019 |
Therapeutic impact of Nintedanib with paclitaxel and/or a PD-L1 antibody in preclinical models of orthotopic primary or metastatic triple negative breast cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Immunological; B7-H1 Antigen; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Indoles; Kaplan-Meier Estimate; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Paclitaxel; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2019 |
A peptide-modified solid lipid nanoparticle formulation of paclitaxel modulates immunity and outperforms dacarbazine in a murine melanoma model.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Calreticulin; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cytokines; Dacarbazine; Disease Models, Animal; Female; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Nanoparticles; Paclitaxel; Peptides; Survival Rate; Tissue Distribution | 2019 |
Circulating microRNA and automated motion analysis as novel methods of assessing chemotherapy-induced peripheral neuropathy in mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Automation; Behavior, Animal; Biomarkers; Circulating MicroRNA; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Movement; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases; Sciatic Nerve | 2019 |
Evodiamine ameliorates paclitaxel-induced neuropathic pain by inhibiting inflammation and maintaining mitochondrial anti-oxidant functions.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cytokines; Disease Models, Animal; Ganglia, Spinal; Humans; Inflammation Mediators; Male; Membrane Potential, Mitochondrial; Mitochondria; Neuralgia; Oxidative Stress; Paclitaxel; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phytotherapy; Quinazolines; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Cells, Cultured; Uncoupling Protein 2 | 2019 |
Cisplatin educates CD8+ T cells to prevent and resolve chemotherapy-induced peripheral neuropathy in mice.
Topics: Animals; Antineoplastic Agents; CD8-Positive T-Lymphocytes; Cisplatin; Disease Models, Animal; Female; Hyperalgesia; Male; Mice, Transgenic; Paclitaxel; Pain; Peripheral Nervous System Diseases | 2019 |
Paclitaxel Enhances the Innate Immunity by Promoting NLRP3 Inflammasome Activation in Macrophages.
Topics: Acetylation; Acetyltransferases; Animals; Bacterial Infections; Cell Line; Disease Models, Animal; Epothilones; Gene Knockdown Techniques; Humans; Immunity, Innate; Inflammasomes; Interleukin-1beta; Macrophages; Mice; Microtubule Proteins; Microtubules; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Paclitaxel; Pyroptosis; Signal Transduction; THP-1 Cells; Tubulin | 2019 |
MSC-Delivered Soluble TRAIL and Paclitaxel as Novel Combinatory Treatment for Pancreatic Adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell- and Tissue-Based Therapy; Combined Modality Therapy; Disease Models, Animal; Humans; Mesenchymal Stem Cells; Mice, Nude; Models, Theoretical; Neoplasm Transplantation; Paclitaxel; Pancreatic Neoplasms; TNF-Related Apoptosis-Inducing Ligand; Transplantation, Heterologous; Treatment Outcome | 2019 |
Prevention of cancer dormancy by Fbxw7 ablation eradicates disseminated tumor cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bone Marrow; Bone Marrow Cells; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cohort Studies; Datasets as Topic; Disease Models, Animal; Drug Resistance, Neoplasm; F-Box-WD Repeat-Containing Protein 7; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Kaplan-Meier Estimate; MCF-7 Cells; Mice; Neoplasm Recurrence, Local; Paclitaxel; Prognosis; Spheroids, Cellular; Xenograft Model Antitumor Assays | 2019 |
Differential effect of LPS and paclitaxel on microglial functional phenotypes and circulating cytokines: the possible role of CX3CR1 and IL-4/10 in blocking persistent inflammation.
Topics: Animals; Antineoplastic Agents, Phytogenic; CX3C Chemokine Receptor 1; Disease Models, Animal; Inflammation; Interleukin-10; Interleukin-4; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Neuralgia; Paclitaxel; Phenotype | 2019 |
A fruit fly model for studying paclitaxel-induced peripheral neuropathy and hyperalgesia.
Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Disease Models, Animal; Drosophila melanogaster; Female; Male; Nociception; Paclitaxel | 2018 |
Indomethacin plus minocycline coadministration relieves chemotherapy and antiretroviral drug-induced neuropathic pain in a cannabinoid receptors-dependent manner.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Retroviral Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Female; Indomethacin; Mice, Inbred BALB C; Minocycline; Neuralgia; Paclitaxel; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Zalcitabine | 2019 |
An Experimental Study of Paclitaxel Embolisation During Drug Coated Balloon Angioplasty.
Topics: Angioplasty, Balloon; Animals; Chemoembolization, Therapeutic; Coated Materials, Biocompatible; Disease Models, Animal; Femoral Artery; Male; Paclitaxel; Peripheral Arterial Disease; Popliteal Artery; Rabbits; Renal Artery; Treatment Outcome | 2019 |
Magnetophoretic Delivery of a Tumor-Priming Agent for Chemotherapy of Metastatic Murine Breast Cancer.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Drug Liberation; Female; Ferric Compounds; Injections, Intravenous; Magnetite Nanoparticles; Mice; Mice, Inbred BALB C; Paclitaxel; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome; Tumor Burden; Tumor Microenvironment | 2019 |
Exosomes from M1-Polarized Macrophages Enhance Paclitaxel Antitumor Activity by Activating Macrophages-Mediated Inflammation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Exosomes; Immunologic Factors; Macrophage Activation; Macrophages; Mice; Paclitaxel; Treatment Outcome | 2019 |
Losartan, an Angiotensin II Type 1 Receptor Antagonist, Alleviates Mechanical Hyperalgesia in a Rat Model of Chemotherapy-Induced Neuropathic Pain by Inhibiting Inflammatory Cytokines in the Dorsal Root Ganglia.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cytokines; Disease Models, Animal; Ganglia, Spinal; Glial Fibrillary Acidic Protein; Hyperalgesia; Hypnotics and Sedatives; Inflammation Mediators; Losartan; Male; Neuralgia; Neurons; NF-kappa B; Paclitaxel; Phosphorylation; Rats, Sprague-Dawley | 2019 |
The Preparation, Determination of a Flexible Complex Liposome Co-Loaded with Cabazitaxel and β-Elemene, and Animal Pharmacodynamics on Paclitaxel-Resistant Lung Adenocarcinoma.
Topics: Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; Liposomes; Mice; Molecular Structure; Paclitaxel; Particle Size; Sesquiterpenes; Taxoids; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
Carboplatin/paclitaxel, E7-vaccination and intravaginal CpG as tri-therapy towards efficient regression of genital HPV16 tumors.
Topics: Administration, Intravaginal; Animals; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Combined Modality Therapy; Disease Models, Animal; Female; Genital Neoplasms, Female; Human papillomavirus 16; Humans; Immunotherapy; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Oligodeoxyribonucleotides; Paclitaxel; Papillomavirus E7 Proteins; Papillomavirus Infections; Toll-Like Receptor 9; Vaccines, Synthetic; Vagina | 2019 |
Effective Delivery of a Microtubule Polymerization Inhibitor Synergizes with Standard Regimens in Models of Pancreatic Ductal Adenocarcinoma.
Topics: Albumins; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gemcitabine; Humans; Immunohistochemistry; Mice; Microtubules; Paclitaxel; Pancreatic Neoplasms; Protein Multimerization; Tubulin Modulators; Xenograft Model Antitumor Assays | 2019 |
Nano-drug System Based on Hierarchical Drug Release for Deep Localized/Systematic Cascade Tumor Therapy Stimulating Antitumor Immune Responses.
Topics: Animals; Antineoplastic Agents; Carcinoma; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Drug Liberation; Drug Therapy; Gold; HeLa Cells; Humans; Hyperthermia, Induced; Immunologic Factors; Immunotherapy; Mice; Models, Biological; Nanocomposites; Neoplasm Transplantation; Paclitaxel; Photosensitizing Agents; Phototherapy; Transplantation, Heterologous; Treatment Outcome | 2019 |
Long noncoding RNA CASC2 promotes paclitaxel resistance in breast cancer through regulation of miR-18a-5p/CDK19.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kinases; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Paclitaxel; RNA, Long Noncoding | 2019 |
Cathepsin L-mediated resistance of paclitaxel and cisplatin is mediated by distinct regulatory mechanisms.
Topics: Animals; Antineoplastic Agents; Cathepsin L; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Drug Resistance, Neoplasm; Early Growth Response Protein 1; Genes, Reporter; Humans; Male; Paclitaxel; Promoter Regions, Genetic; Protein Binding; Smad3 Protein; Xenograft Model Antitumor Assays | 2019 |
Intravenous administration of manuka honey inhibits tumor growth and improves host survival when used in combination with chemotherapy in a melanoma mouse model.
Topics: Administration, Intravenous; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Honey; Humans; Leptospermum; Male; Melanoma; Mice; Necrosis; Paclitaxel; Tumor Burden | 2013 |
The effect of short-term intra-arterial delivery of paclitaxel on neointimal hyperplasia and the local thrombotic environment after angioplasty.
Topics: Angioplasty, Balloon; Animals; Biopsy, Needle; Carotid Artery Injuries; Carotid Artery, Common; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Hyperplasia; Immunohistochemistry; Infusions, Intra-Arterial; Male; Neointima; Paclitaxel; Random Allocation; Rats; Rats, Wistar; Risk Assessment; Thromboplastin; Thrombosis; Time Factors; Tissue Plasminogen Activator; Treatment Outcome | 2013 |
HDAC6 mutations rescue human tau-induced microtubule defects in Drosophila.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Epothilones; Histone Deacetylase 6; Histone Deacetylases; Humans; Mice; Mice, Knockout; Microtubules; Muscle Cells; Mutation; Neurons; Paclitaxel; Phosphorylation; tau Proteins; Tubulin Modulators | 2013 |
Combined delivery of paclitaxel and tanespimycin via micellar nanocarriers: pharmacokinetics, efficacy and metabolomic analysis.
Topics: Animals; Benzoquinones; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Female; Humans; Lactams, Macrocyclic; Metabolome; Metabolomics; Mice; Micelles; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Spectroscopy, Near-Infrared; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Cutting balloon combined with paclitaxel-eluting balloon for treatment of in-stent restenosis.
Topics: Angioplasty, Balloon, Coronary; Animals; Apoptosis; Cardiac Catheters; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Equipment Design; Immunohistochemistry; In Situ Nick-End Labeling; Metals; Muscle, Smooth, Vascular; Neointima; Paclitaxel; Prosthesis Design; Stents; Swine; Swine, Miniature; Time Factors | 2013 |
Effects of repeated milnacipran and fluvoxamine treatment on mechanical allodynia in a mouse paclitaxel-induced neuropathic pain model.
Topics: Animals; Cyclopropanes; Disease Models, Animal; Fluvoxamine; Hyperalgesia; Male; Mice; Milnacipran; Neuralgia; Paclitaxel | 2013 |
TLR4 is a novel determinant of the response to paclitaxel in breast cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Autocrine Communication; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Cytokine; Toll-Like Receptor 4; Transcriptional Activation | 2013 |
The effect of antineoplastic drugs in a male spontaneous mammary tumor model.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Proliferation; Cisplatin; Disease Models, Animal; Female; Male; Mammary Neoplasms, Experimental; Mice, Transgenic; Neoplasm Proteins; Paclitaxel; Phenotype; Receptors, Estrogen; Receptors, Progesterone | 2014 |
Ovarian tumor initiating cell populations persist following paclitaxel and carboplatin chemotherapy treatment in vivo.
Topics: AC133 Antigen; Animals; Antigens, CD; Antigens, Ly; Antineoplastic Agents; Carboplatin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Gene Expression; Glycoproteins; Membrane Proteins; Mice; Neoplastic Stem Cells; Ovarian Neoplasms; Paclitaxel; Peptides; Tumor Burden | 2013 |
Comparative benefits of Nab-paclitaxel over gemcitabine or polysorbate-based docetaxel in experimental pancreatic cancer.
Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Disease Models, Animal; Docetaxel; Female; Gemcitabine; Humans; Inhibitory Concentration 50; Neoplasms, Experimental; Paclitaxel; Pancreatic Neoplasms; Stathmin; Stromal Cells; Taxoids; Tubulin; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Integrity of stent polymer layer after drug-eluting stent implantation: in vivo comparison of sirolimus-, paclitaxel-, zotarolimus- and everolimus-eluting stents.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Vessel Prosthesis Implantation; Coated Materials, Biocompatible; Coronary Restenosis; Disease Models, Animal; Drug-Eluting Stents; Everolimus; Immunosuppressive Agents; Paclitaxel; Prosthesis Design; Sirolimus; Swine | 2014 |
A bioengineered 3D ovarian cancer model for the assessment of peptidase-mediated enhancement of spheroid growth and intraperitoneal spread.
Topics: Animals; Bioengineering; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Mice; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Paclitaxel; Peptide Hydrolases; Peritoneum; Spheroids, Cellular | 2013 |
[The pilot study of the effect of paclitaxel by local application on scar formation after airway injury in rabbits].
Topics: Administration, Topical; Animals; Apoptosis; Cicatrix; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Male; Paclitaxel; Pilot Projects; Rabbits; Random Allocation; Trachea; Tracheal Stenosis; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2013 |
Metformin impairs endothelialization after placement of newer generation drug eluting stents.
Topics: Angioplasty, Balloon; Animals; Disease Models, Animal; Drug-Eluting Stents; Endothelium, Vascular; Everolimus; Hypoglycemic Agents; Iliac Artery; Immunosuppressive Agents; Male; Metformin; Paclitaxel; Rabbits; Sirolimus; Thrombosis; Tubulin Modulators | 2013 |
Stromal disrupting effects of nab-paclitaxel in pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Collagen; Deoxycytidine; Disease Models, Animal; Elasticity Imaging Techniques; Endosonography; Female; Fibroblasts; Gemcitabine; Humans; Male; Mice; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Pancreatic Neoplasms; Positron-Emission Tomography | 2013 |
A preliminary study of imaging paclitaxel-induced tumor apoptosis with (99)Tc(m)-His10-Annexin V.
Topics: Animals; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Histidine; Humans; Lung Neoplasms; Mice; Organotechnetium Compounds; Paclitaxel; Radiopharmaceuticals | 2013 |
Carrier-free functionalized multidrug nanorods for synergistic cancer therapy.
Topics: Animals; Camptothecin; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Drug Synergism; Drug Therapy, Combination; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; KB Cells; MCF-7 Cells; Methotrexate; Mice; Mice, Inbred BALB C; Nanoparticles; Nanotubes; Neoplasms; Paclitaxel | 2013 |
Stent healing response following delivery of paclitaxel via durable polymeric matrix versus iopromide-based balloon coating in the familial hypercholesterolaemic swine model of coronary injury.
Topics: Angioplasty, Balloon, Coronary; Animals; Cardiovascular Agents; Constriction, Pathologic; Coronary Artery Disease; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Iohexol; Neointima; Paclitaxel; Polymers; Swine | 2013 |
Tissue uptake, distribution, and healing response after delivery of paclitaxel via second-generation iopromide-based balloon coating: a comparison with the first-generation technology in the iliofemoral porcine model.
Topics: Angioplasty, Balloon; Animals; Arterial Occlusive Diseases; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Constriction, Pathologic; Contrast Media; Disease Models, Animal; Equipment Design; Femoral Artery; Fibrosis; Hyperlipoproteinemia Type II; Iliac Artery; Iohexol; Neointima; Paclitaxel; Radiography; Sus scrofa; Tissue Distribution; Vascular Access Devices; Wound Healing | 2013 |
Janus nanogels of PEGylated Taxol and PLGA-PEG-PLGA copolymer for cancer therapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Disease Models, Animal; Doxorubicin; Drug Carriers; Drug Therapy, Combination; Female; Half-Life; Mice; Mice, Inbred BALB C; Nanogels; Paclitaxel; Polyethylene Glycols; Polyethyleneimine; Polyglactin 910 | 2013 |
Nab-paclitaxel is an active drug in preclinical model of pediatric solid tumors.
Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Female; Humans; Mice; Neoplasms; Neuroblastoma; Osteosarcoma; Paclitaxel; Rhabdomyosarcoma; Xenograft Model Antitumor Assays | 2013 |
The dual PI3K/mTOR inhibitor NVP-BEZ235 enhances nab-paclitaxel antitumor response in experimental gastric cancer.
Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Disease Models, Animal; Drug Synergism; Female; Humans; Imidazoles; Mice; Mice, Inbred NOD; Mice, SCID; Nanoparticles; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinolines; Stomach Neoplasms; Tumor Cells, Cultured | 2013 |
Microtubule-stabilizing agents delay the onset of EAE through inhibition of migration.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autoantigens; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Disease Progression; Docetaxel; Drug Synergism; Encephalomyelitis, Autoimmune, Experimental; Epothilones; Growth Inhibitors; Humans; Lactones; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubules; Multiple Sclerosis; Paclitaxel; Taxoids | 2013 |
Static magnetic fields increase tumor microvessel leakiness and improve antitumoral efficacy in combination with paclitaxel.
Topics: Albumins; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Combined Modality Therapy; Disease Models, Animal; Endothelial Cells; Leukocytes; Magnetic Fields; Male; Mesocricetus; Microcirculation; Microscopy, Fluorescence; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Permeability | 2014 |
Tumor targeting effects of a novel modified paclitaxel-loaded discoidal mimic high density lipoproteins.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomimetic Materials; Breast Neoplasms; Cholesterol Esters; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Humans; Lipoproteins, HDL; Male; MCF-7 Cells; Mice; Mice, Inbred ICR; Paclitaxel; Particle Size; Phosphatidylcholine-Sterol O-Acyltransferase; Tissue Distribution | 2013 |
Novel isoprenoyl nanoassembled prodrug for paclitaxel delivery.
Topics: Animals; Antineoplastic Agents; Body Weight; Butadienes; Disease Models, Animal; Disease Progression; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Hemiterpenes; Humans; Inhibitory Concentration 50; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Pentanes; Prodrugs; Tumor Cells, Cultured | 2013 |
The significance of microscopic mass spectrometry with high resolution in the visualisation of drug distribution.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Monitoring; Female; Mass Spectrometry; Mice; Microscopy; Neoplasms; Paclitaxel; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tissue Distribution; Tumor Burden | 2013 |
Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression; Gene Knockdown Techniques; Humans; Inhibitor of Apoptosis Proteins; Mice; Paclitaxel; Receptor, ErbB-2; Receptor, ErbB-3; Survivin; Trastuzumab; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Inhibition of neo-intimal hyperplasia in porcine coronary arteries utilizing a novel paclitaxel-coated scoring balloon catheter.
Topics: Angioplasty, Balloon, Coronary; Animals; Antineoplastic Agents, Phytogenic; Cardiac Catheters; Coated Materials, Biocompatible; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Equipment Design; Hyperplasia; Male; Paclitaxel; Swine; Tunica Intima | 2014 |
Establishment of paclitaxel-resistant breast cancer cell line and nude mice models, and underlying multidrug resistance mechanisms in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Culture Techniques; Cell Cycle; Cell Proliferation; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Tumor Cells, Cultured | 2013 |
Chemical renal denervation in the rat.
Topics: Animals; Chromatography, Liquid; Denervation; Disease Models, Animal; Dose-Response Relationship, Drug; Guanethidine; Hypertension; Kidney; Mass Spectrometry; Norepinephrine; Paclitaxel; Phenol; Rats; Rats, Sprague-Dawley; Salicylic Acid; Saline Solution, Hypertonic | 2014 |
Combinations of TLR ligands: a promising approach in cancer immunotherapy.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Imidazoles; Immunomodulation; Immunotherapy; Ligands; Lymphocytes; Mice; Neoplasms; Paclitaxel; Poly I-C; Toll-Like Receptors; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
[Study of claudin-4 in the diagnosis and treatment of endometrial carcinoma].
Topics: Animals; Cell Line, Tumor; Cisplatin; Claudin-4; Disease Models, Animal; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Real-Time Polymerase Chain Reaction; RNA, Messenger; Transplantation, Heterologous | 2013 |
Broad spectrum and prolonged efficacy of dimiracetam in models of neuropathic pain.
Topics: Analysis of Variance; Animals; Anti-Retroviral Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Hyperalgesia; Imidazoles; Male; Neuralgia; Osteoarthritis, Knee; Paclitaxel; Pain Measurement; Pain Threshold; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vincristine; Weight-Bearing | 2014 |
Experimental development of an intra-abdominal chemohyperthermia model using a closed abdomen technique and a PRS-1.0 Combat CO2 recirculation system.
Topics: Abdomen; Animals; Antineoplastic Agents; Blood Gas Analysis; Body Temperature; Carbon Dioxide; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Disease Models, Animal; Female; Hemodynamics; Hyperthermia, Induced; Infusions, Parenteral; Paclitaxel; Peritoneal Neoplasms; Swine; Treatment Outcome | 2014 |
The TrkB+ cancer stem cells contribute to post-chemotherapy recurrence of triple-negative breast cancers in an orthotopic mouse model.
Topics: Aged; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Factor 4; Membrane Glycoproteins; Mice; Middle Aged; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Paclitaxel; Paracrine Communication; Protein-Tyrosine Kinases; Receptor, trkB; Signal Transduction; Triple Negative Breast Neoplasms | 2015 |
Paclitaxel coating on the terminal portion of hemodialysis grafts effectively suppresses neointimal hyperplasia in a porcine model.
Topics: Animals; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Cardiovascular Agents; Carotid Artery, Common; Coated Materials, Biocompatible; Constriction, Pathologic; Disease Models, Animal; Female; Graft Occlusion, Vascular; Hyperplasia; Jugular Veins; Neointima; Paclitaxel; Polytetrafluoroethylene; Prosthesis Design; Renal Dialysis; Swine; Time Factors | 2015 |
Enhancement of nab-paclitaxel antitumor activity through addition of multitargeting antiangiogenic agents in experimental pancreatic cancer.
Topics: Albumins; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Synergism; Female; Humans; Mice; Paclitaxel; Pancreatic Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Translymphatic chemotherapy targeting sentinel lymph nodes using a novel phospholipid polymer-Paclitaxel conjugate.
Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Lymph Nodes; Lymphatic Metastasis; Male; Methacrylates; Neoplasms; Paclitaxel; Phosphorylcholine; Rats; Sentinel Lymph Node Biopsy | 2014 |
Gamma-Fe2O3 nanoparticles increase therapeutic efficacy of combination with paclitaxel and anti-ABCG2 monoclonal antibody on multiple myeloma cancer stem cells in mouse model.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caspases; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Humans; Magnetite Nanoparticles; Mice; Multiple Myeloma; Neoplasm Proteins; Neoplastic Stem Cells; NF-kappa B; Paclitaxel; Particle Size; Signal Transduction; Succimer; Tumor Burden | 2014 |
Prophylactic cannabinoid administration blocks the development of paclitaxel-induced neuropathic nociception during analgesic treatment and following cessation of drug delivery.
Topics: Analgesics; Animals; Antineoplastic Agents, Phytogenic; Cannabinoids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hyperalgesia; Male; Motor Activity; Neuralgia; Paclitaxel; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Cord | 2014 |
Toll-like receptor 4 signaling contributes to Paclitaxel-induced peripheral neuropathy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Male; Myeloid Differentiation Factor 88; Nerve Tissue Proteins; Neurons; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Polysaccharides; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Toll-Like Receptor 4 | 2014 |
Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Chemokine CCL2; Chromones; Disease Models, Animal; Dronabinol; Female; Hyperalgesia; Indoles; Male; Mice, Inbred C57BL; Mice, Knockout; Paclitaxel; Random Allocation; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; Spinal Cord; Tumor Necrosis Factor-alpha | 2015 |
Mechanisms promoting escape from mitotic stress-induced tumor cell death.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Heterografts; Humans; Lung Neoplasms; Mice; Microtubules; Mitosis; Paclitaxel; Protein Binding; RNA Interference; Spindle Apparatus; Stress, Physiological; Tripartite Motif Proteins; Tumor Burden; Ubiquitin-Protein Ligases | 2014 |
The anti-diabetic drug metformin protects against chemotherapy-induced peripheral neuropathy in a mouse model.
Topics: Animals; Cisplatin; Disease Models, Animal; Hyperalgesia; Hypoglycemic Agents; Metformin; Mice, Inbred C57BL; Nerve Fibers; Neuralgia; Paclitaxel; Peripheral Nervous System Diseases; Protective Agents | 2014 |
PEG-farnesyl thiosalicylic acid telodendrimer micelles as an improved formulation for targeted delivery of paclitaxel.
Topics: Animals; Breast Neoplasms; Disease Models, Animal; Drug Carriers; Farnesol; Female; HCT116 Cells; Hemolysis; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Polyethylene Glycols; Salicylates | 2014 |
Independent evaluation of the anatomical and behavioral effects of Taxol in rat models of spinal cord injury.
Topics: Amino Acids, Diamino; Analysis of Variance; Animals; Antigens; Blood-Brain Barrier; Collagen Type IV; Disease Models, Animal; Female; Fibronectins; Gene Expression Regulation; Motor Activity; Paclitaxel; Proteoglycans; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Time Factors; Tubulin Modulators | 2014 |
Determining the mechanisms of lapatinib-induced diarrhoea using a rat model.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Disease Models, Animal; ErbB Receptors; Goblet Cells; Intestinal Mucosa; Intestines; Lapatinib; Male; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Wistar; Receptor, ErbB-2 | 2014 |
A new 2α,5α,10β,14β-tetraacetoxy-4(20),11-taxadiene (SIA) derivative overcomes paclitaxel resistance by inhibiting MAPK signaling and increasing paclitaxel accumulation in breast cancer cells.
Topics: Acetates; Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Diterpenes; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; MAP Kinase Signaling System; Paclitaxel; Xenograft Model Antitumor Assays | 2014 |
Involvement of the chemokine CCL3 and the purinoceptor P2X7 in the spinal cord in paclitaxel-induced mechanical allodynia.
Topics: Animals; Antibodies; Antineoplastic Agents, Phytogenic; Chemokine CCL3; Disease Models, Animal; Gene Expression Regulation; Hyperalgesia; Male; Paclitaxel; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, CCR5; Receptors, Purinergic P2X7; RNA, Messenger; Spinal Cord; Time Factors | 2014 |
Colchicine suppresses atrial fibrillation in failing heart.
Topics: Action Potentials; Animals; Atrial Fibrillation; Blotting, Western; Colchicine; Collagen; Disease Models, Animal; Heart Failure; Ion Channels; Paclitaxel; Polymerase Chain Reaction; Proteins; Rabbits; RNA, Messenger; Signal Transduction | 2014 |
Low-dose paclitaxel improves the therapeutic efficacy of recombinant adenovirus encoding CCL21 chemokine against murine cancer.
Topics: Adenoviridae; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemokine CCL21; Cytokines; Cytotoxicity, Immunologic; Disease Models, Animal; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Melanoma, Experimental; Mice; Neoplasms; Neovascularization, Pathologic; Paclitaxel; T-Cell Antigen Receptor Specificity; T-Lymphocyte Subsets; Tumor Burden | 2014 |
Paclitaxel-loaded PEG-PE-based micellar nanopreparations targeted with tumor-specific landscape phage fusion protein enhance apoptosis and efficiently reduce tumors.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Delivery Systems; Female; Humans; Mice; Micelles; Nanoparticles; Neoplasms; Paclitaxel; Phosphatidylethanolamines; Polyethylene Glycols; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
The prophylactic effects of a traditional Japanese medicine, goshajinkigan, on paclitaxel-induced peripheral neuropathy and its mechanism of action.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cells, Cultured; Disease Models, Animal; Drug Administration Schedule; Drugs, Chinese Herbal; Female; Ganglia, Spinal; Gene Expression Profiling; Gene Expression Regulation; Hyperalgesia; Mice; Mice, Transgenic; Mitochondria; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Inbred F344; Sensory Receptor Cells; Time Factors; TRPV Cation Channels | 2014 |
A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Antineoplastic Agents, Phytogenic; Cytokines; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Hyperalgesia; Male; NADP; Neuralgia; Neuroglia; NF-kappa B; Oxidation-Reduction; Paclitaxel; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord; Tumor Necrosis Factor-alpha | 2014 |
Dual-layer surface coating of PLGA-based nanoparticles provides slow-release drug delivery to achieve metronomic therapy in a paclitaxel-resistant murine ovarian cancer model.
Topics: Administration, Metronomic; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; Mice; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2014 |
Biological effect of orbital atherectomy and adjunctive paclitaxel-coated balloon therapy on vascular healing and drug retention: early experimental insights into the familial hypercholesterolaemic swine model of femoral artery stenosis.
Topics: Angioplasty, Balloon; Animals; Antineoplastic Agents, Phytogenic; Atherectomy; Combined Modality Therapy; Constriction, Pathologic; Disease Models, Animal; Femoral Artery; Hyperlipoproteinemia Type II; Paclitaxel; Peripheral Arterial Disease; Swine; Tomography, Optical Coherence; Ultrasonography, Interventional; Wound Healing | 2014 |
"Glowing head" mice: a genetic tool enabling reliable preclinical image-based evaluation of cancers in immunocompetent allografts.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Genes, Reporter; Immunocompromised Host; Kaplan-Meier Estimate; Luciferases; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Paclitaxel; Pituitary Gland; Transplantation, Homologous | 2014 |
Lysophosphatidic acid and its receptors LPA1 and LPA3 mediate paclitaxel-induced neuropathic pain in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dizocilpine Maleate; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuralgia; Paclitaxel; Pain Measurement; Phospholipases A2; Piperidines; Receptors, Lysophosphatidic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spinal Cord Dorsal Horn; Time Factors | 2014 |
Bu-zhong-yi-qi pill alleviate the chemotherapy-related fatigue in 4 T1 murine breast cancer model.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Disease Models, Animal; Drugs, Chinese Herbal; Fatigue; Female; Humans; Magnoliopsida; Malondialdehyde; Mice; Paclitaxel; Phytotherapy; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Taxol stabilizes gap junctions and reduces ischemic ventricular arrhythmias in rats in vivo.
Topics: Action Potentials; Animals; Antineoplastic Agents, Phytogenic; Arrhythmias, Cardiac; Connexin 43; Disease Models, Animal; Electrocardiography; Gap Junctions; Gene Expression Regulation; Myocardial Ischemia; Paclitaxel; Protein Multimerization; Protein Transport; Rats; Tubulin | 2015 |
Investigation of protective role of curcumin against paclitaxel-induced inner ear damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Disease Models, Animal; Ear, Inner; Hearing Loss, Sensorineural; Otoacoustic Emissions, Spontaneous; Paclitaxel; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2015 |
BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; BRCA1 Protein; Cell Line, Tumor; Cell Movement; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Female; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression; Gene Silencing; Humans; Inhibitor of Apoptosis Proteins; Mice; Neoplastic Stem Cells; Paclitaxel; Peptide Fragments; Phenotype; Proteolysis; RNA Interference; RNA, Small Interfering; Signal Transduction; Survivin; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio rerio.
Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Endocytosis; Endothelial Cells; Exosomes; Genes, Reporter; Green Fluorescent Proteins; Heterografts; Humans; Neoplasm Transplantation; Paclitaxel; Particle Size; Technology, Pharmaceutical; Time Factors; Tumor Burden; Zebrafish | 2015 |
Multifunctional Polymeric Micelles Co-loaded with Anti-Survivin siRNA and Paclitaxel Overcome Drug Resistance in an Animal Model of Ovarian Cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Down-Regulation; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Mice; Micelles; Microtubules; Ovarian Neoplasms; Paclitaxel; RNA, Messenger; RNA, Small Interfering; Survivin; Xenograft Model Antitumor Assays | 2015 |
MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Hyaluronan Receptors; Hyaluronic Acid; Nanoparticles; Ovarian Neoplasms; Paclitaxel; RNA Interference; RNA, Small Interfering; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
A novel neutralizing antibody targeting pregnancy-associated plasma protein-a inhibits ovarian cancer growth and ascites accumulation in patient mouse tumorgrafts.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Antineoplastic Agents; Ascites; Carboplatin; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression; Humans; Immunohistochemistry; Mice; Ovarian Neoplasms; Paclitaxel; Pregnancy-Associated Plasma Protein-A; Prognosis; Xenograft Model Antitumor Assays | 2015 |
Comprehensive analysis of the GABAergic system gene expression profile in the anterior cingulate cortex of mice with Paclitaxel-induced neuropathic pain.
Topics: Animals; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gyrus Cinguli; Humans; Mice; Neuralgia; Paclitaxel; Receptors, GABA-A; RNA, Messenger; Transcriptome | 2015 |
Gender differences in a mouse model of chemotherapy-induced neuropathic pain.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cisplatin; Disease Models, Animal; Female; Injections, Intraperitoneal; Male; Mice; Neuralgia; Paclitaxel; Sex Factors | 2016 |
Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice.
Topics: Acetanilides; Analgesics; Animals; Benzamides; Capsaicin; Cold Temperature; Disease Models, Animal; Formaldehyde; Hyperalgesia; Isothiocyanates; Male; Mice; Neuralgia; Oximes; Paclitaxel; Pain Measurement; Purines; Thiophenes; Touch; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels | 2015 |
MiR-1204 sensitizes nasopharyngeal carcinoma cells to paclitaxel both in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays | 2015 |
Transplant-mediated enhancement of spinal cord GABAergic inhibition reverses paclitaxel-induced mechanical and heat hypersensitivity.
Topics: Activating Transcription Factor 3; Animals; Antineoplastic Agents, Phytogenic; Cell Count; Cell Transplantation; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Paclitaxel; Pain Measurement; Pain Threshold; Spinal Cord; Vesicular Inhibitory Amino Acid Transport Proteins | 2015 |
Valvuloplasty with a paclitaxel-eluting balloon prevents restenosis in an experimental animal model of aortic stenosis.
Topics: Animals; Aortic Valve Stenosis; Atherosclerosis; Balloon Valvuloplasty; Calcinosis; Calcium; Disease Models, Animal; Paclitaxel; Proliferating Cell Nuclear Antigen; Rabbits; Random Allocation; Recurrence; Ultrasonography; X-Ray Microtomography | 2014 |
Blocking the GABA transporter GAT-1 ameliorates spinal GABAergic disinhibition and neuropathic pain induced by paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Disease Models, Animal; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Neuralgia; Paclitaxel; Rats; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn | 2015 |
An exercise regimen prevents development paclitaxel induced peripheral neuropathy in a mouse model.
Topics: Action Potentials; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Male; Mice; Neural Conduction; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Physical Conditioning, Animal | 2015 |
miR-218 targets survivin and regulates resistance to chemotherapeutics in breast cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Binding Sites; Breast Neoplasms; Caspases; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Mice; MicroRNAs; Paclitaxel; RNA, Messenger; Survivin; Transcriptome; Xenograft Model Antitumor Assays | 2015 |
CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain.
Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Male; Mice; Mice, Knockout; Neuralgia; Paclitaxel; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Treatment Outcome | 2015 |
Temporary placement of a paclitaxel or rapamycin-eluting stent is effective to reduce stenting induced inflammatory reaction and scaring in benign cardia stricture models.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cardia; Cicatrix; Constriction, Pathologic; Disease Models, Animal; Dogs; Drug-Eluting Stents; Esophageal Sphincter, Lower; Esophageal Stenosis; Female; Humans; Inflammation; Male; Manometry; Paclitaxel; Random Allocation; Sirolimus; Time Factors | 2014 |
Conventional chemotherapy and oncogenic pathway targeting in ovarian carcinosarcoma using a patient-derived tumorgraft.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinosarcoma; Disease Models, Animal; Female; Gene Expression Profiling; Humans; Maximum Tolerated Dose; Mice; Molecular Targeted Therapy; Ovarian Neoplasms; Paclitaxel; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Sensory neuron subpopulation-specific dysregulation of intracellular calcium in a rat model of chemotherapy-induced peripheral neuropathy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Calcium; Disease Models, Animal; Ganglia, Spinal; Intracellular Space; Male; Membrane Potentials; Nociceptive Pain; Nociceptors; Paclitaxel; Pain Measurement; Peripheral Nervous System Diseases; Rats, Sprague-Dawley; Skin; Touch | 2015 |
Paclitaxel improves outcome from traumatic brain injury.
Topics: Animals; Brain Injuries; Disease Models, Animal; Gait Disorders, Neurologic; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Paclitaxel; Treatment Outcome; Tubulin Modulators | 2015 |
Cancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic Platform.
Topics: Animals; Apoptosis; Cell Culture Techniques; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Fibroblast Growth Factors; Fibroblasts; Heat-Shock Proteins; Humans; Microfluidics; Neoplasms; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays | 2015 |
Impact of Paclitaxel Dose on Tissue Pharmacokinetics and Vascular Healing: A Comparative Drug-Coated Balloon Study in the Familial Hypercholesterolemic Swine Model of Superficial Femoral In-Stent Restenosis.
Topics: Animals; Cardiovascular Agents; Coated Materials, Biocompatible; Constriction, Pathologic; Disease Models, Animal; Endovascular Procedures; Femoral Artery; Fibrin; Hyperlipoproteinemia Type II; Metals; Neointima; Paclitaxel; Peripheral Arterial Disease; Radiography; Stents; Swine; Tissue Distribution; Vascular Access Devices; Wound Healing | 2015 |
Bulleyaconitine A depresses neuropathic pain and potentiation at C-fiber synapses in spinal dorsal horn induced by paclitaxel in rats.
Topics: Aconitine; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Hyperalgesia; In Vitro Techniques; Male; Nerve Fibers, Unmyelinated; Neuralgia; Paclitaxel; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Synaptic Potentials; Time Factors | 2015 |
Prevention of chemotherapy-induced peripheral neuropathy by the small-molecule inhibitor pifithrin-μ.
Topics: Analgesics; Animals; Antineoplastic Agents, Phytogenic; Cisplatin; Disease Models, Animal; Female; Ganglia, Spinal; Humans; Hyperalgesia; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mitochondria; Paclitaxel; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Sulfonamides; Ubiquitin Thiolesterase; Xenograft Model Antitumor Assays | 2015 |
Bevacizumab-Induced Inhibition of Angiogenesis Promotes a More Homogeneous Intratumoral Distribution of Paclitaxel, Improving the Antitumor Response.
Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Female; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Mice; Neoplasms; Paclitaxel; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xenograft Model Antitumor Assays | 2016 |
Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis, and possible involvement of the adenosine system.
Topics: Adenosine; Alkaloids; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Bignoniaceae; Disease Models, Animal; Edema; Freund's Adjuvant; Hyperalgesia; Interleukin-1beta; Medicine, Chinese Traditional; Mice; Monoterpenes; Motor Activity; Paclitaxel; Pain Measurement; Theobromine; Theophylline; Xanthines | 2015 |
Increased expression of MyD88 and association with paclitaxel resistance in breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Knockdown Techniques; Humans; Mice; Middle Aged; Myeloid Differentiation Factor 88; Neoplasm Grading; Neoplasm Staging; NF-kappa B; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays | 2016 |
Biological effect on drug distribution and vascular healing via paclitaxel-coated balloon technology in drug eluting stent restenosis swine model.
Topics: Animals; Cardiac Catheterization; Cardiac Catheters; Cardiovascular Agents; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Equipment and Supplies; Fibrin; Metals; Neointima; Paclitaxel; Percutaneous Coronary Intervention; Stents; Swine; Tissue Distribution; Tomography, Optical Coherence; Wound Healing | 2016 |
Two-Step Delivery: Exploiting the Partition Coefficient Concept to Increase Intratumoral Paclitaxel Concentrations In vivo Using Responsive Nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Mesothelioma; Mice; Nanoparticles; Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays | 2016 |
SPARC-Independent Delivery of Nab-Paclitaxel without Depleting Tumor Stroma in Patient-Derived Pancreatic Cancer Xenografts.
Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Deoxycytidine; Disease Models, Animal; Drug Synergism; Female; Gemcitabine; Humans; Mice; Microcirculation; Osteonectin; Paclitaxel; Pancreatic Neoplasms; Stromal Cells; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Linalool-Incorporated Nanoparticles as a Novel Anticancer Agent for Epithelial Ovarian Carcinoma.
Topics: Acyclic Monoterpenes; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Membrane Potential, Mitochondrial; Mice; Monoterpenes; Nanoparticles; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Reactive Oxygen Species; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Low-dose paclitaxel ameliorates renal fibrosis by suppressing transforming growth factor-β1-induced plasminogen activator inhibitor-1 signaling.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Matrix Proteins; Fibrosis; Kidney; Kidney Diseases; Male; Mitogen-Activated Protein Kinases; Paclitaxel; Plasminogen Activator Inhibitor 1; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Smad3 Protein; Time Factors; Transforming Growth Factor beta1; Tubulin Modulators; Ureteral Obstruction | 2016 |
Paclitaxel-Loaded Polymersomes for Enhanced Intraperitoneal Chemotherapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Carriers; Drug Compounding; Drug Liberation; Drug Stability; Humans; Injections, Intraperitoneal; Mice; Paclitaxel; Peritoneal Neoplasms; Polymers; Tissue Distribution; Xenograft Model Antitumor Assays | 2016 |
Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Humans; Magnetic Resonance Imaging; Mice; Paclitaxel; Survival Analysis; Treatment Outcome | 2016 |
Combination Therapy using Co-encapsulated Resveratrol and Paclitaxel in Liposomes for Drug Resistance Reversal in Breast Cancer Cells in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Drug Resistance, Multiple; Female; Liposomes; Mice, Inbred BALB C; Paclitaxel; Resveratrol; Stilbenes; Treatment Outcome; Tubulin Modulators | 2016 |
Paclitaxel Associated With Lipid Nanoparticles as a New Antiscarring Agent in Experimental Glaucoma Surgery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cicatrix; Conjunctiva; Disease Models, Animal; Drug Carriers; Follow-Up Studies; Glaucoma; Injections; Intraocular Pressure; Lipids; Male; Nanoparticles; Paclitaxel; Postoperative Complications; Rabbits; Trabeculectomy | 2016 |
Dorsal Root Ganglion Infiltration by Macrophages Contributes to Paclitaxel Chemotherapy-Induced Peripheral Neuropathy.
Topics: Anesthetics; Animals; Antibodies; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents, Phytogenic; Bone Density Conservation Agents; Cell Movement; Chemokine CCL2; Clodronic Acid; Disease Models, Animal; Drug Administration Routes; Ganglia, Spinal; GAP-43 Protein; Hyperalgesia; Isoflurane; Lipopolysaccharides; Macrophages; Male; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Spinal Cord; Spleen; Time Factors; Tumor Necrosis Factor-alpha; Ubiquitin Thiolesterase | 2016 |
Therapeutic potential of RQ-00311651, a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; Female; HEK293 Cells; Humans; Hyperalgesia; Male; Mice; Neuralgia; Nociception; Paclitaxel; Rats; Rats, Wistar; Visceral Pain | 2016 |
Evaluation of expansile nanoparticle tumor localization and efficacy in a cancer stem cell-derived model of pancreatic peritoneal carcinomatosis.
Topics: Animals; Carcinoma; Disease Models, Animal; Drug Delivery Systems; Humans; Nanoparticles; Neoplastic Stem Cells; Paclitaxel; Pancreatic Neoplasms; Peritoneum; Rats; Rhodamines; Xenograft Model Antitumor Assays | 2016 |
Pharmacokinetic Evaluation of Two Paclitaxel-Coated Balloons with Different Drug Load in a Short-Term Porcine Study.
Topics: Angioplasty, Balloon; Animals; Coated Materials, Biocompatible; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperplasia; Iliac Artery; Male; Paclitaxel; Sus scrofa; Swine; Tubulin Modulators | 2016 |
Identification of fluocinolone acetonide to prevent paclitaxel-induced peripheral neuropathy.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Axons; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fluocinolone Acetonide; Ganglia, Spinal; Mice; Nerve Fibers; Neurons; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley | 2016 |
Osimertinib (AZD9291) Enhanced the Efficacy of Chemotherapeutic Agents in ABCB1- and ABCG2-Overexpressing Cells In Vitro, In Vivo, and Ex Vivo.
Topics: Acrylamides; Aniline Compounds; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Cell Membrane; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Flow Cytometry; Gene Expression; Humans; Mice; Paclitaxel; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Xenograft Model Antitumor Assays | 2016 |
Cyclin-Dependent Kinase 11 (CDK11) Is Required for Ovarian Cancer Cell Growth In Vitro and In Vivo, and Its Inhibition Causes Apoptosis and Sensitizes Cells to Paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinases; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mice; Ovarian Neoplasms; Paclitaxel; RNA Interference; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2016 |
mir-500-Mediated GAD67 Downregulation Contributes to Neuropathic Pain.
Topics: Action Potentials; Animals; Antagomirs; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Down-Regulation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyperalgesia; Inhibitory Postsynaptic Potentials; Male; MicroRNAs; Neuralgia; Paclitaxel; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Transcription Activator-Like Effector Nucleases | 2016 |
Low doses of paclitaxel enhance liver metastasis of breast cancer cells in the mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Epithelial-Mesenchymal Transition; Estrogens; Female; Gene Expression; Gene Expression Profiling; Humans; Inflammation Mediators; Liver; Liver Neoplasms; Mice; Neoplasm Invasiveness; NF-kappa B; Paclitaxel | 2016 |
Oxidative stress in the development, maintenance and resolution of paclitaxel-induced painful neuropathy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; Cells, Cultured; Disease Models, Animal; Disease Progression; Ganglia, Spinal; Hyperalgesia; Lumbar Vertebrae; Male; Microglia; Neurons; Oxidative Stress; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats, Sprague-Dawley; Reactive Oxygen Species; Spinal Cord | 2016 |
Paclitaxel causes degeneration of both central and peripheral axon branches of dorsal root ganglia in mice.
Topics: Animals; Antineoplastic Agents; Axons; Disease Models, Animal; Female; Ganglia, Spinal; Male; Mice, Inbred C57BL; Microscopy, Electron; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases; Sciatic Nerve; Spinal Cord | 2016 |
CHK1 Inhibition Radiosensitizes Head and Neck Cancers to Paclitaxel-Based Chemoradiotherapy.
Topics: Aminopyridines; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 1; Chemoradiotherapy; Combined Modality Therapy; Disease Models, Animal; Female; Head and Neck Neoplasms; Humans; Mice; Mitosis; Neoplastic Stem Cells; Paclitaxel; Protein Kinase Inhibitors; Pyrimidines; Radiation Tolerance; Radiation-Sensitizing Agents; Radiation, Ionizing; Xenograft Model Antitumor Assays | 2016 |
Rescuing Impaired Re-endothelialization of Drug-Eluting Stents Using the Hepatocyte Growth Factor.
Topics: Angioplasty, Balloon; Animals; Apoptosis; Cardiovascular Agents; Carotid Arteries; Carotid Artery Diseases; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Eluting Stents; Endothelial Progenitor Cells; Hepatocyte Growth Factor; Hypercholesterolemia; Injections, Subcutaneous; Male; Neointima; Paclitaxel; Rabbits; Re-Epithelialization; Time Factors | 2016 |
Ultrasound-Mediated Microbubble Destruction (UMMD) Facilitates the Delivery of CA19-9 Targeted and Paclitaxel Loaded mPEG-PLGA-PLL Nanoparticles in Pancreatic Cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; CA-19-9 Antigen; Cell Survival; Disease Models, Animal; Drug Carriers; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Microbubbles; Nanoparticles; Paclitaxel; Pancreatic Neoplasms; Polyesters; Polyethylene Glycols; Survival Analysis; Treatment Outcome; Tumor Cells, Cultured; Ultrasonography | 2016 |
Involvement of high mobility group box 1 in the development and maintenance of chemotherapy-induced peripheral neuropathy in rats.
Topics: Animals; Antibodies, Neutralizing; Antineoplastic Agents; Disease Models, Animal; Ganglia, Spinal; HMGB1 Protein; Hyperalgesia; Male; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Recombinant Proteins; Sciatic Nerve; Thrombomodulin; Toll-Like Receptor 4; Vincristine | 2016 |
Combination of Paclitaxel and MG1 oncolytic virus as a successful strategy for breast cancer treatment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Disease Models, Animal; Female; Humans; Interferon-beta; Mice; Oncolytic Virotherapy; Oncolytic Viruses; Paclitaxel; Tumor Burden; Virus Replication; Xenograft Model Antitumor Assays | 2016 |
Alternating electric fields (TTFields) in combination with paclitaxel are therapeutically effective against ovarian cancer cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Disease Models, Animal; Female; Humans; Mice; Ovarian Neoplasms; Paclitaxel; Treatment Outcome; Xenograft Model Antitumor Assays | 2016 |
Knockdown of Hypoxia-Inducible Factor 1α Improved the Efficacy of Low-Dose Metronomic Chemotherapy of Paclitaxel in Human Colon Cancer Xenografts.
Topics: Administration, Metronomic; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Neovascularization, Pathologic; Paclitaxel; RNA Interference; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2017 |
Styrene maleic acid-encapsulated paclitaxel micelles: antitumor activity and toxicity studies following oral administration in a murine orthotopic colon cancer model.
Topics: Administration, Oral; Alanine Transaminase; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Body Weight; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Drug Liberation; Female; Humans; Maleates; Maximum Tolerated Dose; Mice, Inbred BALB C; Micelles; Microvessels; Neovascularization, Physiologic; Paclitaxel; Polystyrenes; Static Electricity; Toxicity Tests | 2016 |
Avian axons undergo Wallerian degeneration after injury and stress.
Topics: Analysis of Variance; Animals; Axons; Axotomy; Calcium; Cells, Cultured; Disease Models, Animal; Finches; Microscopy, Confocal; Microscopy, Fluorescence; NAD; Nerve Degeneration; Paclitaxel; Pressure; Retinal Ganglion Cells; Stress, Physiological; Vincristine; Wallerian Degeneration | 2016 |
Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Diterpenes, Kaurane; Drug Synergism; Humans; Male; Membrane Potential, Mitochondrial; Mice; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Reactive Oxygen Species; Signal Transduction; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2016 |
A New Concept of Enhancing Immuno-Chemotherapeutic Effects Against B16F10 Tumor
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Carriers; Galactosylceramides; Immunotherapy; Liposomes; Melanoma; Mice, Inbred C57BL; Nanostructures; Paclitaxel; Treatment Outcome | 2016 |
miR-186 regulates chemo-sensitivity to paclitaxel via targeting MAPT in non-small cell lung cancer (NSCLC).
Topics: 3' Untranslated Regions; Adult; Aged; Animals; Apoptosis; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Lung Neoplasms; Mice; MicroRNAs; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Paclitaxel; Prognosis; RNA Interference; tau Proteins; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Biological effect on restenosis and vascular healing of encapsulated paclitaxel nanocrystals delivered via coated balloon technology in the familial hypercholesterolaemic swine model of in-stent restenosis.
Topics: Angiography; Angioplasty, Balloon, Coronary; Animals; Antineoplastic Agents; Disease Models, Animal; Femoral Artery; Graft Occlusion, Vascular; Hyperlipoproteinemia Type II; Iliac Artery; Metals; Nanoparticles; Neointima; Paclitaxel; Peripheral Vascular Diseases; Stents; Sus scrofa; Swine; Tomography, Optical Coherence; Wound Healing | 2016 |
MitoVitE, a mitochondria-targeted antioxidant, limits paclitaxel-induced oxidative stress and mitochondrial damage in vitro, and paclitaxel-induced mechanical hypersensitivity in a rat pain model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Disease Models, Animal; Hyperalgesia; In Vitro Techniques; Male; Mitochondria; Neuralgia; Organophosphorus Compounds; Oxidative Stress; Paclitaxel; Rats; Rats, Sprague-Dawley; Ubiquinone | 2016 |
MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; MAP Kinase Signaling System; Mice; Microfilament Proteins; Microtubules; Neoplasm Metastasis; Paclitaxel; Protein Isoforms; Triple Negative Breast Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Paclitaxel Drug-eluting Tracheal Stent Could Reduce Granulation Tissue Formation in a Canine Model.
Topics: Animals; Bronchoscopy; Disease Models, Animal; Dogs; Drug-Eluting Stents; Granulation Tissue; Microscopy, Electron, Scanning; Paclitaxel; Trachea; Tracheal Stenosis | 2016 |
Paclitaxel inhibits post-traumatic recurrent laryngeal nerve regeneration into the posterior cricoarytenoid muscle in a canine model.
Topics: Animals; Disease Models, Animal; Dogs; Humans; Injections, Intramuscular; Laryngeal Muscles; Nerve Regeneration; Paclitaxel; Random Allocation; Recurrent Laryngeal Nerve Injuries; Reference Values; Vincristine; Vocal Cord Paralysis | 2017 |
Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3.2) in paclitaxel-induced peripheral neuropathy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Azabicyclo Compounds; Benzamides; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Humans; Hyperalgesia; Male; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Spinal Cord; Sulfonamides; Toll-Like Receptor 4 | 2017 |
Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models.
Topics: Acetylation; Animals; Antineoplastic Agents; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Synergism; Female; Histone Deacetylase Inhibitors; Humans; Paclitaxel; Spindle Apparatus; Tubulin; Xenograft Model Antitumor Assays | 2017 |
Heterogeneity of paclitaxel distribution in different tumor models assessed by MALDI mass spectrometry imaging.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Female; Heterografts; Humans; Image Processing, Computer-Assisted; Male; Mice; Neoplasm Transplantation; Neoplasms; Paclitaxel; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Ultrasound-mediated destruction of oxygen and paclitaxel loaded dual-targeting microbubbles for intraperitoneal treatment of ovarian cancer xenografts.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Humans; Infusions, Parenteral; Mice; Microbubbles; Ovarian Neoplasms; Oxygen; Paclitaxel; Ultrasonics; Xenograft Model Antitumor Assays | 2017 |
Patient-Derived Xenograft Models of Epithelial Ovarian Cancer for Preclinical Studies.
Topics: Adult; Animals; Antineoplastic Agents; Biomarkers, Tumor; Biopsy; Carboplatin; Carcinoma, Ovarian Epithelial; Disease Models, Animal; Drug Evaluation, Preclinical; ErbB Receptors; Female; Genomic Instability; Heterografts; Humans; Mice; Middle Aged; Molecular Targeted Therapy; Neoplasm Grading; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Translational Research, Biomedical; Xenograft Model Antitumor Assays | 2017 |
Epigenetic upregulation of CXCL12 expression mediates antitubulin chemotherapeutics-induced neuropathic pain.
Topics: Animals; Antibodies; Chemokine CXCL12; Disease Models, Animal; Evoked Potentials; Excitatory Postsynaptic Potentials; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuralgia; Paclitaxel; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; RNA, Small Interfering; Spinal Cord; STAT3 Transcription Factor; Time Factors; Tubulin; Up-Regulation; Vincristine | 2017 |
MiR-1307 promotes ovarian cancer cell chemoresistance by targeting the ING5 expression.
Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Mice; MicroRNAs; Ovarian Neoplasms; Paclitaxel; RNA Interference; Transcription Factors; Transfection; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2017 |
Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer.
Topics: Albumins; Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Macrophage Activation; Macrophages; Paclitaxel; Pancreatic Neoplasms; Pinocytosis; Toll-Like Receptor 4; Xenograft Model Antitumor Assays | 2017 |
Effects of Taxol on Regeneration in a Rat Sciatic Nerve Transection Model.
Topics: Adrenergic Neurons; Animals; Axons; Calcitonin Gene-Related Peptide; Disease Models, Animal; Electrophysiological Phenomena; Gene Expression Regulation; Hot Temperature; Hyperalgesia; Macrophages; Motor Activity; Nerve Regeneration; Paclitaxel; Rats, Sprague-Dawley; RNA, Messenger; Sciatic Nerve; Silicone Elastomers; Spinal Cord Dorsal Horn; Stilbamidines | 2017 |
PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.
Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Centromere; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; DNA Copy Number Variations; Drug Resistance, Neoplasm; Female; Gene Amplification; Gene Editing; Gene Knockout Techniques; Genomic Instability; Genotype; Humans; Mice; Mutation; Paclitaxel; Phenotype; Tumor Suppressor Protein p53 | 2017 |
Anti-proliferative effect of Jesridonin on paclitaxel-resistant EC109 human esophageal carcinoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Mice; Neoplastic Stem Cells; Paclitaxel; Xenograft Model Antitumor Assays | 2017 |
A novel intraperitoneal metastatic xenograft mouse model for survival outcome assessment of esophageal adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; Esophageal Neoplasms; Heterografts; Mice; Neoplasm Transplantation; Paclitaxel; Peritoneal Neoplasms | 2017 |
The effect of paclitaxel-eluting covered metal stents versus covered metal stents in a rabbit esophageal squamous carcinoma model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug-Eluting Stents; Esophageal Neoplasms; Female; Male; Paclitaxel; Rabbits | 2017 |
Radionuclide I-131 Labeled Albumin-Paclitaxel Nanoparticles for Synergistic Combined Chemo-radioisotope Therapy of Cancer.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Disease Models, Animal; Iodine Radioisotopes; Mice; Mice, Nude; Nanoparticles; Paclitaxel; Serum Albumin; Serum Albumin, Human; Treatment Outcome | 2017 |
The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression; Humans; Male; Mice; Models, Molecular; Molecular Conformation; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Piperidines; Protein Binding; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Regorafenib overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter in colorectal cancer: In vitro and in vivo study.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Mice; Paclitaxel; Phenylurea Compounds; Pyridines; Xenograft Model Antitumor Assays | 2017 |
Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Hyaluronan Receptors; Mice; Mice, Nude; Neoplastic Stem Cells; NF-kappa B; Oxyquinoline; Paclitaxel; Xenograft Model Antitumor Assays | 2009 |
Implantation of paclitaxel-eluting stent impairs the vascular compliance of arteries in porcine coronary stenting model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Female; Inflammation; Male; Metals; Nitroglycerin; Paclitaxel; Swine; Vasodilation | 2009 |
Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Peptides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2008 |
MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models.
Topics: Analgesics; Animals; Benzofurans; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Ligation; Motor Activity; Neuralgia; Paclitaxel; Pain Measurement; Piperidines; Radioligand Assay; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Species Specificity; Spinal Nerves | 2008 |
Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.
Topics: Adenocarcinoma; Adult; Aged; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Carboplatin; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cetuximab; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Etoposide; Female; Gemcitabine; Gene Expression Profiling; Genes, ras; Humans; Immunoblotting; Lung Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Middle Aged; Mutation; Oligonucleotide Array Sequence Analysis; Paclitaxel; Polymerase Chain Reaction; Prognosis; Protein Kinase Inhibitors; Quinazolines; Radiation-Sensitizing Agents; Small Cell Lung Carcinoma; Tumor Suppressor Protein p53; Vinblastine; Vinorelbine; Xenograft Model Antitumor Assays | 2008 |
In situ blood-brain barrier permeability of a C-10 paclitaxel carbamate.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamates; Central Nervous System; Disease Models, Animal; Mice; Molecular Structure; Neurodegenerative Diseases; Paclitaxel; Permeability; Structure-Activity Relationship | 2008 |
Efficacy assessment of sustained intraperitoneal paclitaxel therapy in a murine model of ovarian cancer using bioluminescent imaging.
Topics: Animals; Body Weight; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Disease Progression; Female; Humans; Injections, Intraperitoneal; Luminescent Measurements; Mice; Mice, SCID; Ovarian Neoplasms; Paclitaxel; Survival Rate; Xenograft Model Antitumor Assays | 2008 |
IL-13 cytotoxin has potent antitumor activity and synergizes with paclitaxel in a mouse model of oral squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Exotoxins; Humans; Interleukin-13; Mice; Mouth Neoplasms; Paclitaxel; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tongue Neoplasms; Transplantation, Heterologous | 2009 |
Effect of the chronic combined administration of cisplatin and paclitaxel in a rat model of peripheral neurotoxicity.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cisplatin; Disease Models, Animal; Drug Administration Schedule; Female; Ganglia, Spinal; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Weight Loss | 2009 |
Histologic influence of paclitaxel-eluting covered metallic stents in a canine biliary model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Coated Materials, Biocompatible; Common Bile Duct; Disease Models, Animal; Dogs; Drug-Eluting Stents; Epithelium; Equipment Safety; Hyperplasia; Male; Mucous Membrane; Paclitaxel; Polyurethanes | 2009 |
Intimal proliferation and restenosis in paclitaxel-eluting stents with aminoparylene as carrier substance in swines.
Topics: Animals; Cell Proliferation; Chromium Alloys; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug Hypersensitivity; Drug-Eluting Stents; Incidence; Metals; Paclitaxel; Polymers; Stents; Swine; Tunica Intima; Xylenes | 2009 |
Comparison of two different paclitaxel-coated balloon catheters in the porcine coronary restenosis model.
Topics: Animals; Catheterization; Coated Materials, Biocompatible; Coronary Restenosis; Disease Models, Animal; Drug-Eluting Stents; Graft Occlusion, Vascular; Humans; Paclitaxel; Swine; Tubulin Modulators | 2009 |
Comparative healing response after sirolimus- and paclitaxel-eluting stent implantation in a pig model of restenosis.
Topics: Angioplasty, Balloon, Coronary; Animals; Cardiovascular Agents; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Inflammation; Paclitaxel; Platelet Endothelial Cell Adhesion Molecule-1; Platelet-Derived Growth Factor; Sirolimus; Swine; Swine, Miniature; Time Factors; Vascular Endothelial Growth Factor A; Wound Healing | 2009 |
Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; Female; Gemcitabine; Humans; Interphase; Ligands; Mice; Mice, Inbred C57BL; Paclitaxel; Pancreatic Neoplasms; Receptors, sigma; Survival Analysis | 2009 |
Prevention of paclitaxel and cisplatin induced ovarian damage in rats by a gonadotropin-releasing hormone agonist.
Topics: Animals; Anovulation; Antineoplastic Agents; Cisplatin; Disease Models, Animal; Drug Administration Schedule; Female; Fertility; Fertility Agents, Female; Gonadotropin-Releasing Hormone; Infertility, Female; Injections, Subcutaneous; Leuprolide; Ovarian Follicle; Paclitaxel; Rats; Rats, Wistar | 2010 |
Paclitaxel: friend or foe for systemic lupus erythematosus?
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Humans; Lupus Erythematosus, Systemic; Mice; Mice, Inbred NZB; Paclitaxel | 2009 |
Evaluation of a novel slow-release paclitaxel-eluting stent with a bioabsorbable polymeric surface coating.
Topics: Animals; Antineoplastic Agents, Phytogenic; Coated Materials, Biocompatible; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Drug-Eluting Stents; Lactic Acid; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prosthesis Design; Swine | 2008 |
Sensitization of ABCB1 overexpressing cells to chemotherapeutic agents by FG020326 via binding to ABCB1 and inhibiting its function.
Topics: Acrylates; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Imidazoles; KB Cells; Mice; Mice, Nude; Multidrug Resistance-Associated Proteins; Paclitaxel; Vincristine; Xenograft Model Antitumor Assays | 2009 |
Effect of drug-eluting metal stents in benign esophageal stricture: an in vivo animal study.
Topics: Alloys; Animals; Antineoplastic Agents, Phytogenic; Cell Division; Disease Models, Animal; Dogs; Drug-Eluting Stents; Epithelium; Equipment Design; Esophageal Stenosis; Esophagoscopy; Esophagus; Focal Adhesions; Granulation Tissue; Mucous Membrane; Paclitaxel | 2009 |
Endothelium-dependent vasomotor dysfunction in pig coronary arteries with Paclitaxel-eluting stents is associated with inflammation and oxidative stress.
Topics: Animals; Antineoplastic Agents, Phytogenic; Coronary Artery Disease; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Endothelium, Vascular; Inflammation; Oxidative Stress; Paclitaxel; Swine | 2009 |
Comparison of inflammatory response after implantation of sirolimus- and paclitaxel-eluting stents in porcine coronary arteries.
Topics: Animals; Arteritis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Eosinophils; Female; Fibrin; Fibrosis; Granuloma, Foreign-Body; Paclitaxel; Sirolimus; Swine; Tunica Intima | 2009 |
Adjuvant treatment with locally delivered OncoGel delays the onset of paresis after surgical resection of experimental spinal column metastasis.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Disease Models, Animal; Drug Delivery Systems; Female; Hindlimb; Neoplasm Transplantation; Neurologic Examination; Paclitaxel; Radiotherapy, Adjuvant; Rats; Rats, Inbred F344; Spinal Neoplasms; Statistics, Nonparametric; Time Factors | 2009 |
Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models.
Topics: Analgesics; Animals; Botulinum Toxins, Type A; Carrageenan; Dantrolene; Disease Models, Animal; Edema; Hyperalgesia; Inflammation; Injections; Male; Motor Activity; Paclitaxel; Polyneuropathies; Rats; Rats, Sprague-Dawley | 2009 |
Aerosol delivery of liposomal formulated paclitaxel and vitamin E analog reduces murine mammary tumor burden and metastases.
Topics: Administration, Inhalation; Aerosols; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Immunohistochemistry; Liposomes; Lymph Nodes; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neovascularization, Pathologic; Paclitaxel; Tumor Burden; Vitamin E | 2009 |
Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane.
Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Lung Neoplasms; Melanoma, Experimental; Mice; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Proteins; Transplantation, Heterologous; Treatment Outcome | 2010 |
PLGA nanoparticles stabilized with cationic surfactant: safety studies and application in oral delivery of paclitaxel to treat chemical-induced breast cancer in rat.
Topics: Administration, Oral; Animals; Breast Neoplasms; Caco-2 Cells; Cations; Cells, Cultured; Disease Models, Animal; Drug Carriers; Drug Stability; Female; Humans; Nanocapsules; Paclitaxel; Particle Size; Polyglactin 910; Rats; Rats, Sprague-Dawley; Surface-Active Agents | 2009 |
Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer.
Topics: Afatinib; Amphiregulin; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cetuximab; Disease Models, Animal; Drug Resistance, Neoplasm; EGF Family of Proteins; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Profiling; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Male; Mice; Mice, Nude; Mice, Transgenic; Mutation; Neoplasm Transplantation; Paclitaxel; Protein Kinase Inhibitors; Quinazolines; Transplantation, Heterologous; Tumor Cells, Cultured | 2009 |
Identification and characterization of cancer stem-like cells from primary carcinoma of the cervix uteri.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Hyaluronan Receptors; Imines; Immunoenzyme Techniques; Mice; Mice, Nude; Neoplastic Stem Cells; Paclitaxel; Spheroids, Cellular; Thiazines; Uterine Cervical Neoplasms | 2009 |
Combined anti-angiogenic therapy against VEGF and integrin alphaVbeta3 in an orthotopic model of ovarian cancer.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis; Bevacizumab; Blotting, Western; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; Immunoenzyme Techniques; Immunoprecipitation; Integrin alphaVbeta3; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2009 |
Olesoxime (cholest-4-en-3-one, oxime): analgesic and neuroprotective effects in a rat model of painful peripheral neuropathy produced by the chemotherapeutic agent, paclitaxel.
Topics: Analysis of Variance; Animals; Area Under Curve; Cholestenones; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Evoked Potentials; Hyperalgesia; Male; Nerve Fibers; Neuralgia; Neuroprotective Agents; Paclitaxel; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Ubiquitin Thiolesterase | 2009 |
Differential pharmacodynamic effects of paclitaxel formulations in an intracranial rat brain tumor model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Brain Neoplasms; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Screening Assays, Antitumor; Glycerol; Liposomes; Male; Maximum Tolerated Dose; Models, Theoretical; Neutropenia; Paclitaxel; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains; Tumor Burden | 2010 |
Lesion complexity determines arterial drug distribution after local drug delivery.
Topics: Animals; Aorta, Abdominal; Atherosclerosis; Cholesterol; Disease Models, Animal; Drug Delivery Systems; Drug-Eluting Stents; Everolimus; Humans; Male; Paclitaxel; Protein Binding; Rabbits; Sirolimus; Tissue Distribution; Tunica Intima | 2010 |
Inhibition of human gastric carcinoma cell growth in vitro and in vivo by cladosporol isolated from the paclitaxel-producing strain Alternaria alternata var. monosporus.
Topics: Alternaria; Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthalenes; Neoplasms; Paclitaxel; Plant Bark; Stomach Neoplasms; Taxus; Transplantation, Heterologous | 2009 |
(-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma.
Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Female; Heat-Shock Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Paclitaxel | 2010 |
Letter by Virmani et al regarding article, "Drug-eluting stents in animals and patients: where do we stand today?".
Topics: Animals; Disease Models, Animal; Drug-Eluting Stents; Humans; Paclitaxel; Risk Factors; Sirolimus; Swine; Thrombosis | 2010 |
Down-modulation of survivin expression and inhibition of tumor growth in vivo by EZN-3042, a locked nucleic acid antisense oligonucleotide.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Liver Regeneration; Lung Neoplasms; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Oligonucleotides; Oligonucleotides, Antisense; Paclitaxel; RNA, Messenger; Survivin; Treatment Outcome; Xenograft Model Antitumor Assays | 2010 |
Novel biodegradable polymer-coated, paclitaxel-eluting stent inhibits neointimal formation in porcine coronary arteries.
Topics: Absorbable Implants; Animals; Coated Materials, Biocompatible; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Eluting Stents; Hyperplasia; Materials Testing; Paclitaxel; Polyesters; Swine; Tunica Intima | 2010 |
Targeted molecular therapy of head and neck squamous cell carcinoma with the tyrosine kinase inhibitor vandetanib in a mouse model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Disease Models, Animal; ErbB Receptors; Flow Cytometry; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Nude; Molecular Targeted Therapy; Paclitaxel; Piperidines; Protein-Tyrosine Kinases; Quinazolines; Random Allocation; Sensitivity and Specificity; Survival Rate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2011 |
Chemotherapy induces macrophage chemoattractant protein-1 production in ovarian cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cell Line, Tumor; Chemokine CCL2; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Macrophages; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Signal Transduction; Up-Regulation | 2010 |
Characterization and preparation of core-shell type nanoparticle for encapsulation of anticancer drug.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Chitosan; Cholesterol; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Design; Drug Screening Assays, Antitumor; Female; Mice; Mice, Inbred BALB C; Molecular Conformation; Molecular Weight; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Particle Size; Polyethylene Glycols; Solubility; Surface Properties | 2010 |
Radiation-guided drug delivery to mouse models of lung cancer.
Topics: Albumins; Amino Acid Sequence; Animals; Biological Availability; Carcinoma, Large Cell; Carcinoma, Lewis Lung; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Guinea Pigs; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Molecular Sequence Data; Paclitaxel; Peptides; Rabbits; Tissue Distribution; Xenograft Model Antitumor Assays | 2010 |
Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Female; Humans; Mice; Mice, Nude; Paclitaxel; Permeability; Treatment Outcome; Xenograft Model Antitumor Assays | 2010 |
Neurophysiological and neuropathological characterization of new murine models of chemotherapy-induced chronic peripheral neuropathies.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Body Weight; Boronic Acids; Bortezomib; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ganglia, Spinal; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Nerve Fibers, Myelinated; Neural Conduction; Paclitaxel; Peripheral Nervous System Diseases; Pyrazines; Sciatic Nerve | 2010 |
Anti-tumor effects of adenovirus containing human growth hormone sequences in a mouse model of human ovarian cancer.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Base Sequence; Carboplatin; Combined Modality Therapy; Disease Models, Animal; Female; Human Growth Hormone; Humans; Injections, Intraperitoneal; Mice; Mice, SCID; Ovarian Neoplasms; Paclitaxel | 2010 |
In vivo activity of novel anti-ErbB2 antibody chA21 alone and with Paclitaxel or Trastuzumab in breast and ovarian cancer xenograft models.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Female; Humans; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Ovarian Neoplasms; Paclitaxel; Receptor, ErbB-2; Signal Transduction; Trastuzumab; Xenograft Model Antitumor Assays | 2011 |
Intraepidermal nerve fiber loss corresponds to the development of taxol-induced hyperalgesia and can be prevented by treatment with minocycline.
Topics: Animals; Disease Models, Animal; Epidermis; Hyperalgesia; Male; Minocycline; Nerve Fibers; Neurotoxins; Paclitaxel; Rats; Rats, Sprague-Dawley | 2011 |
Dose response to Paclitaxel-coated balloon catheters in the porcine coronary overstretch and stent implantation model.
Topics: Angioplasty, Balloon, Coronary; Animals; Catheters; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Male; Paclitaxel; Swine; Vascular Diseases | 2011 |
Comparative assessment of drug-eluting balloons in an advanced porcine model of coronary restenosis.
Topics: Angioplasty, Balloon; Animals; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Endothelium, Vascular; Fibrin; Humans; Neointima; Paclitaxel; Swine; Wound Healing | 2011 |
Evaluation of combined bevacizumab and intraperitoneal carboplatin or paclitaxel therapy in a mouse model of ovarian cancer.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biological Availability; Carboplatin; Disease Models, Animal; Female; Injections, Intraperitoneal; Injections, Intravenous; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Peritoneal Neoplasms; Survival Rate; Xenograft Model Antitumor Assays | 2011 |
Genexol inhibits primary tumour growth and metastases in gemcitabine-resistant pancreatic ductal adenocarcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; Gemcitabine; Humans; Male; Mice; Mice, Nude; Paclitaxel; Pancreatic Neoplasms | 2011 |
Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Membrane; Cell Proliferation; Curcumin; Disease Models, Animal; DNA Fragmentation; Down-Regulation; Drug Synergism; Enzyme Activation; Female; HeLa Cells; Humans; Liposomes; MAP Kinase Signaling System; Methylcholanthrene; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Paclitaxel; Poly Adenosine Diphosphate Ribose; Proto-Oncogene Proteins c-akt; Transcription Factor AP-1; Transcription, Genetic; Tumor Burden; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2011 |
Taxol facilitates axon regeneration in the mature CNS.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Astrocytes; Axons; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glial Fibrillary Acidic Protein; Growth Cones; Macrophages; Myelin Sheath; Nerve Growth Factor; Nerve Regeneration; Optic Nerve Injuries; Paclitaxel; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; rhoA GTP-Binding Protein; Time Factors; Tubulin Modulators | 2011 |
Low-dose paclitaxel enhances the anti-tumor efficacy of GM-CSF surface-modified whole-tumor-cell vaccine in mouse model of prostate cancer.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Combined Modality Therapy; Dendritic Cells; Disease Models, Animal; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Lymphocytes, Tumor-Infiltrating; Male; Mice; Mice, Inbred C57BL; Paclitaxel; Prostatic Neoplasms; T-Lymphocytes; Tumor Cells, Cultured | 2011 |
Effects of Paclitaxel and combination of the drug with radiation therapy in an in vivo model of anaplastic thyroid carcinoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Xenograft Model Antitumor Assays | 2011 |
Antitumour efficacy of two paclitaxel formulations for hyperthermic intraperitoneal chemotherapy (HIPEC) in an in vivo rat model.
Topics: Animals; Antineoplastic Agents; beta-Cyclodextrins; Cell Line, Tumor; Colorectal Neoplasms; Combined Modality Therapy; Disease Models, Animal; Hyperthermia, Induced; Injections, Intraperitoneal; Magnetic Resonance Imaging; Paclitaxel; Peritoneal Neoplasms; Positron-Emission Tomography; Rats; Time Factors; Tumor Burden | 2011 |
Abnormal muscle afferent function in a model of Taxol chemotherapy-induced painful neuropathy.
Topics: Action Potentials; Afferent Pathways; Animals; Antineoplastic Agents; Disease Models, Animal; Male; Muscle, Skeletal; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley | 2011 |
Origin of restenosis after drug-eluting stent implantation in hyperglycemia is inflammatory cells and thrombus.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Body Weight; Coronary Restenosis; Diabetes Mellitus, Type 1; Disease Models, Animal; Drug-Eluting Stents; Fibrin; Humans; Hyaluronic Acid; Hyperglycemia; Inflammation; Male; Paclitaxel; Rats; Rats, Sprague-Dawley; Sirolimus; Thrombosis | 2011 |
Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Cross-Linking Reagents; Disease Models, Animal; Disulfides; Drug Delivery Systems; Female; Hemolysis; Humans; Kinetics; Mice; Mice, Nude; Micelles; Models, Biological; Ovarian Neoplasms; Paclitaxel; Particle Size; Spectroscopy, Near-Infrared; Tissue Distribution; Xenograft Model Antitumor Assays | 2011 |
A novel bioluminescence orthotopic mouse model for advanced lung cancer.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Humans; Injections; Luciferases; Luminescent Measurements; Lung; Lung Neoplasms; Mice; Molecular Imaging; Neoplasm Staging; Paclitaxel; Radiation Injuries, Experimental; Transfection | 2011 |
Low-dose naltrexone suppresses ovarian cancer and exhibits enhanced inhibition in combination with cisplatin.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Proliferation; Cisplatin; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Mice; Mice, Nude; Naltrexone; Neovascularization, Pathologic; Ovarian Neoplasms; Paclitaxel; Treatment Outcome | 2011 |
Cannabidiol prevents the development of cold and mechanical allodynia in paclitaxel-treated female C57Bl6 mice.
Topics: Analgesics; Animals; Behavior, Animal; Cannabidiol; Cold Temperature; Disease Models, Animal; Female; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Paclitaxel; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Sex Factors; Time Factors | 2011 |
Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain.
Topics: Analysis of Variance; Anilides; Animals; Ankyrins; Antineoplastic Agents, Phytogenic; Capsaicin; Carbazoles; Central Nervous System; Cinnamates; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Neuralgia; Oligopeptides; Paclitaxel; Pain Measurement; Physical Stimulation; Protein Kinase C; Pyrroles; Pyrrolidinones; Receptor, PAR-2; Sulfonamides; Time Factors; TRPV Cation Channels; Tryptases; Type C Phospholipases | 2011 |
Paclitaxel-eluting polymer film reduces locoregional recurrence and improves survival in a recurrent sarcoma model: a novel investigational therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chondrosarcoma; Disease Models, Animal; Female; Humans; Mice; Mice, Nude; Nanoparticles; Neoplasm Recurrence, Local; Paclitaxel; Polymers; Survival Rate; Therapies, Investigational; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2012 |
Intracellular delivery of paclitaxel using oil-free, shell cross-linked HSA--multi-armed PEG nanocapsules.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Disease Models, Animal; Flow Cytometry; Humans; Male; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Nanocapsules; Neoplasms, Experimental; Paclitaxel; Polyethylene Glycols; Serum Albumin | 2011 |
The effects of opioid receptor antagonists on electroacupuncture-produced anti-allodynia/hyperalgesia in rats with paclitaxel-evoked peripheral neuropathy.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Electroacupuncture; Hyperalgesia; Male; Naltrexone; Narcotic Antagonists; Paclitaxel; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Random Allocation; Rats; Rats, Sprague-Dawley; Somatostatin | 2011 |
Antinociceptive efficacy of verticinone in murine models of inflammatory pain and paclitaxel induced neuropathic pain.
Topics: Analgesics; Animals; Cevanes; Disease Models, Animal; Inflammation; Mice; Mice, Inbred ICR; Paclitaxel; Pain; Peripheral Nervous System Diseases | 2011 |
Hyaluronic acid-paclitaxel conjugate inhibits growth of human squamous cell carcinomas of the head and neck via a hyaluronic acid-mediated mechanism.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Disease Models, Animal; Humans; Hyaluronan Receptors; Hyaluronic Acid; In Situ Nick-End Labeling; Male; Mice; Mice, Nude; Paclitaxel; Tongue Neoplasms; Transplantation, Heterologous; Treatment Outcome; Tumor Cells, Cultured | 2011 |
Lithium attenuates peripheral neuropathy induced by paclitaxel in rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Lithium Chloride; Male; Motor Neurons; Neural Conduction; Neuroprotective Agents; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley | 2012 |
Paclitaxel-loaded expansile nanoparticles in a multimodal treatment model of malignant mesothelioma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Combined Modality Therapy; Disease Models, Animal; Disease Progression; Female; Humans; Mesothelioma; Mice; Nanoparticles; Paclitaxel; Xenograft Model Antitumor Assays | 2011 |
Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192.
Topics: Animals; Cells, Cultured; Creatinine; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Drug Evaluation, Preclinical; Extracellular Matrix; Fibrosis; Gene Expression Regulation; Hypertension, Renal; Kidney; Male; MicroRNAs; Nephrectomy; Paclitaxel; Proteinuria; Rats; Rats, Wistar; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1; Tubulin Modulators | 2011 |
Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion.
Topics: Animals; Catheterization; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Infusions, Intra-Arterial; Lipoproteins; Mitogen-Activated Protein Kinases; Models, Biological; Monocytes; Muscle, Smooth, Vascular; Paclitaxel; Phosphorylation; PPAR gamma; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Sirolimus; Thiazolidinediones; Thromboplastin; Umbilical Arteries | 2011 |
Paclitaxel therapy potentiates cold hyperalgesia in streptozotocin-induced diabetic rats through enhanced mitochondrial reactive oxygen species production and TRPA1 sensitization.
Topics: Acetylcysteine; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Cold Temperature; Diabetes Mellitus, Experimental; Disease Models, Animal; Ganglia, Spinal; Glucose Tolerance Test; Glutathione Peroxidase; Hydrogen Peroxide; Hyperalgesia; Hypoxanthine Phosphoribosyltransferase; Male; Microscopy, Electron, Transmission; Mitochondria; Paclitaxel; Pain Measurement; Pain Threshold; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sciatic Nerve; Sensory Receptor Cells; Streptozocin; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels | 2012 |
Delayed onset of paresis in rats with experimental intramedullary spinal cord gliosarcoma following intratumoral administration of the paclitaxel delivery system OncoGel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Delivery Systems; Female; Gels; Gliosarcoma; Paclitaxel; Paresis; Rats; Rats, Inbred F344; Spinal Cord Neoplasms | 2012 |
Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cytostatic Agents; Deoxycytidine; Disease Models, Animal; Female; Gemcitabine; Mice; Mice, SCID; Neural Cell Adhesion Molecule L1; Ovarian Neoplasms; Paclitaxel; Pancreatic Neoplasms | 2012 |
The efficacy of abraxane on osteosarcoma xenografts in nude mice and expression of secreted protein, acidic and rich in cysteine.
Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Female; Humans; Maximum Tolerated Dose; Mice; Mice, Nude; Osteonectin; Osteosarcoma; Paclitaxel; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma, Experimental; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Nanoparticle migration and delivery of Paclitaxel to regional lymph nodes in a large animal model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Delivery Systems; Feasibility Studies; Female; Injections, Intradermal; Lymph Nodes; Microscopy, Fluorescence; Nanoparticles; Paclitaxel; Polymers; Spectroscopy, Near-Infrared; Swine | 2012 |
Preclinical evaluation of a novel drug-eluting balloon in an animal model of in-stent stenosis.
Topics: Angioplasty, Balloon, Coronary; Animals; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug Delivery Systems; Female; Humans; Neointima; Paclitaxel; Stents; Swine; Swine, Miniature; Wound Healing | 2013 |
Evidence that spinal astrocytes but not microglia contribute to the pathogenesis of Paclitaxel-induced painful neuropathy.
Topics: Animals; Antineoplastic Agents; Astrocytes; Blotting, Western; Disease Models, Animal; Immunohistochemistry; Male; Microglia; Neuralgia; Paclitaxel; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord | 2012 |
Evaluation of a novel paclitaxel-eluting stent with a bioabsorbable polymeric surface coating in the porcine artery injury model.
Topics: Absorbable Implants; Animals; Constriction, Pathologic; Dioxanes; Disease Models, Animal; Drug-Eluting Stents; Femoral Artery; Microscopy, Electron, Scanning; Paclitaxel; Polymers; Prostheses and Implants; Secondary Prevention; Swine; Tubulin Modulators | 2011 |
A translation inhibitor identified in a Drosophila screen enhances the effect of ionizing radiation and taxol in mammalian models of cancer.
Topics: Animals; Biological Products; Cell Line, Tumor; Combined Modality Therapy; Disease Models, Animal; Drosophila melanogaster; Drug Screening Assays, Antitumor; Humans; Mice; Mutation; Neoplasms; Paclitaxel; Peptides, Cyclic; Protein Biosynthesis; Radiation, Ionizing; Xenograft Model Antitumor Assays | 2012 |
Etodolac, a cyclooxygenase-2 inhibitor, attenuates paclitaxel-induced peripheral neuropathy in a mouse model of mechanical allodynia.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Disease Models, Animal; Drug Interactions; Duloxetine Hydrochloride; Etodolac; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mexiletine; Mice; Paclitaxel; Peripheral Nervous System Diseases; Pregabalin; Thiophenes; Tissue Distribution | 2012 |
A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Axons; Disease Models, Animal; Drosophila; Drosophila Proteins; Eye Proteins; Female; Ganglia, Spinal; Immunohistochemistry; Larva; Mice; Microscopy, Confocal; Nerve Degeneration; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nerves; RNA Interference | 2012 |
Long-term effects on vascular healing of bare metal stents delivered via paclitaxel-coated balloons in the porcine model of restenosis.
Topics: Angioplasty, Balloon, Coronary; Animals; Cardiac Catheters; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Endothelial Cells; Equipment Design; Metals; Neointima; Paclitaxel; Prosthesis Design; Stents; Swine; Swine, Miniature; Time Factors; von Willebrand Factor | 2012 |
Efficient inhibition of colorectal peritoneal carcinomatosis by drug loaded micelles in thermosensitive hydrogel composites.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Erythrocytes; Fluorouracil; Hydrogel, Polyethylene Glycol Dimethacrylate; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Peritoneal Neoplasms; Polyesters; Polyethylene Glycols; Rabbits; Temperature | 2012 |
Targeted antivascular therapy with the apolipoprotein(a) kringle V, rhLK8, inhibits the growth and metastasis of human prostate cancer in an orthotopic nude mouse model.
Topics: Angiogenesis Inhibitors; Animals; Apolipoproteins A; Disease Models, Animal; Humans; Kringles; Male; Mice; Mice, Nude; Neoplasm Metastasis; Paclitaxel; Peptide Fragments; Prostatic Neoplasms; Recombinant Proteins; Xenograft Model Antitumor Assays | 2012 |
nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer.
Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Cytidine Deaminase; Deoxycytidine; Disease Models, Animal; Drug Synergism; Gemcitabine; Mice; Paclitaxel; Pancreatic Neoplasms | 2012 |
The antibody-based delivery of interleukin-12 to the tumor neovasculature eradicates murine models of cancer in combination with paclitaxel.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Female; Humans; Interferon-gamma; Interleukin-12; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Recombinant Fusion Proteins; Single-Chain Antibodies; Tissue Distribution; Treatment Outcome; Tumor Burden | 2012 |
Comparative vascular responses three months after paclitaxel and everolimus-eluting stent implantation in streptozotocin-induced diabetic porcine coronary arteries.
Topics: Animals; Apoptosis; Cardiovascular Agents; Cells, Cultured; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Eluting Stents; Endothelial Cells; Everolimus; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Necrosis; Neointima; Paclitaxel; Percutaneous Coronary Intervention; Prosthesis Design; Sirolimus; Swine; Time Factors; Wound Healing | 2012 |
[Prevention of restenosis in the canine coronary stents through local delivery of paclitaxel using the double-balloon perfusion catheter].
Topics: Angioplasty, Balloon, Coronary; Animals; Catheters; Coronary Restenosis; Disease Models, Animal; Dogs; Injections; Paclitaxel; Stents | 2012 |
Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice.
Topics: Adenosine Triphosphatases; Animals; Axonal Transport; Axons; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Hippocampus; Humans; Mice; Mice, Knockout; Microtubules; Models, Neurological; Mutation; Neurons; Nocodazole; Paclitaxel; Spastic Paraplegia, Hereditary; Spastin; Vinblastine | 2013 |
Electrophysiological features of the mouse tail nerves and their changes in chemotherapy induced peripheral neuropathy (CIPN).
Topics: Animals; Antineoplastic Agents, Phytogenic; Biophysics; Disease Models, Animal; Electric Stimulation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Neural Conduction; Paclitaxel; Peripheral Nervous System Diseases; Reaction Time; Rotarod Performance Test; Species Specificity; Tail; Time Factors | 2012 |
Therapeutic application of injectable thermosensitive hydrogel in preventing local breast cancer recurrence and improving incision wound healing in a mouse model.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Female; Hydrogel, Polyethylene Glycol Dimethacrylate; Mice; Mice, Inbred BALB C; Paclitaxel; Polyesters; Polyethylene Glycols; Secondary Prevention; Temperature; Transplantation, Homologous; Wound Healing | 2012 |
Development of a rat model of oral small molecule receptor tyrosine kinase inhibitor-induced diarrhea.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Disease Models, Animal; Lapatinib; Male; Paclitaxel; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases | 2012 |
2'-Behenoyl-paclitaxel conjugate containing lipid nanoparticles for the treatment of metastatic breast cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Female; Lipids; Mammary Neoplasms, Experimental; Mice; Nanoparticles; Neoplasm Metastasis; Paclitaxel | 2013 |
Improving anti-tumor activity with polymeric micelles entrapping paclitaxel in pulmonary carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Fluorescein-5-isothiocyanate; Injections, Intravenous; Injections, Subcutaneous; Lung Neoplasms; Mice; Mice, Inbred C57BL; Micelles; Paclitaxel; Polyesters; Polyethylene Glycols; Tissue Distribution; Zebrafish | 2012 |
The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB₂ receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy.
Topics: Animals; Benzylamines; Chromones; Cisplatin; Cryopyrin-Associated Periodic Syndromes; Cyclams; Disease Models, Animal; Heterocyclic Compounds; Hyperalgesia; Indoles; Male; Paclitaxel; Peripheral Nervous System Diseases; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, CXCR4; Signal Transduction; Time Factors; Treatment Outcome | 2012 |
Safety and proof-of-concept efficacy of inhaled drug loaded nano- and immunonanoparticles in a c-Raf transgenic lung cancer model.
Topics: Administration, Inhalation; Animals; Antibodies, Immobilized; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Cell Adhesion Molecules; Disease Models, Animal; Drug Delivery Systems; Epithelial Cell Adhesion Molecule; Female; Humans; Lung; Lung Neoplasms; Male; Mice; Mice, Transgenic; Nanoparticles; Paclitaxel; Palmitates; Proto-Oncogene Proteins c-raf; Random Allocation; Surface Properties; Survival Analysis | 2013 |
Evaluation of efficacy and dose response of different paclitaxel-coated balloon formulations in a novel swine model of iliofemoral in-stent restenosis.
Topics: Analysis of Variance; Angioplasty, Balloon; Animals; Antineoplastic Agents, Phytogenic; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Health Status Indicators; Hyperlipoproteinemia Type II; Male; Paclitaxel; Risk Factors; Ultrasonography | 2012 |
Novel model for basaloid triple-negative breast cancer: behavior in vivo and response to therapy.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cell Movement; Disease Models, Animal; Female; Humans; Immunoenzyme Techniques; Lung Neoplasms; Lymphatic Metastasis; Mice; Mice, Nude; Neovascularization, Pathologic; Paclitaxel; Real-Time Polymerase Chain Reaction; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2012 |
Targeted delivery of paclitaxel to EphA2-expressing cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Delivery Systems; Female; Gene Expression; Humans; Male; Mice; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Peptides; Receptor, EphA2; Transplantation, Homologous; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Drug Delivery Systems; Drug Therapy, Combination; Female; Gels; Glioma; Humans; Neoplasm Transplantation; Paclitaxel; Rats; Rats, Inbred F344; Survival Analysis; Temozolomide | 2013 |
Mesenchymal stromal cells primed with Paclitaxel attract and kill leukaemia cells, inhibit angiogenesis and improve survival of leukaemia-bearing mice.
Topics: Animals; Cell Communication; Cell Growth Processes; Cell Line, Tumor; Disease Models, Animal; Humans; Leukemia; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Nude; Neovascularization, Pathologic; Paclitaxel; Xenograft Model Antitumor Assays | 2013 |
Choroidal neovascularization reduced by targeted drug delivery with cationic liposome-encapsulated paclitaxel or targeted photodynamic therapy with verteporfin encapsulated in cationic liposomes.
Topics: Angiogenesis Inhibitors; Animals; Choroidal Neovascularization; Disease Models, Animal; Drug Delivery Systems; Humans; Liposomes; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Paclitaxel; Photochemotherapy; Photosensitizing Agents; Porphyrins; Prodrugs; Vascular Endothelial Growth Factor A; Verteporfin; Wet Macular Degeneration | 2013 |
Antibody to vascular endothelial growth factor slows growth of an androgen-independent xenograft model of prostate cancer.
Topics: Androgens; Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Disease Models, Animal; Drug Therapy, Combination; Endothelial Growth Factors; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Paclitaxel; Prostatic Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Studies with CWR22 xenografts in nude mice suggest that ZD1839 may have a role in the treatment of both androgen-dependent and androgen-independent human prostate cancer.
Topics: Anilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Carboplatin; Disease Models, Animal; ErbB Receptors; Female; Gefitinib; Humans; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Nitriles; Paclitaxel; Prostatic Neoplasms; Protein-Tyrosine Kinases; Quinazolines; Receptors, Androgen; Testosterone; Tosyl Compounds; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2002 |
Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Blotting, Western; Bone Neoplasms; Cell Division; Disease Models, Animal; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Nude; Microcirculation; Neoplasms, Experimental; Paclitaxel; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Prostatic Neoplasms; Protein-Tyrosine Kinases; Pyrimidines; Radiographic Image Enhancement; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tumor Cells, Cultured | 2003 |
Effects of ganglioside on paclitaxel (Taxol) induced neuropathy in rats.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electrophysiology; Female; Gangliosides; Neural Conduction; Paclitaxel; Pain Measurement; Peripheral Nervous System Diseases; Probability; Rats; Rats, Wistar; Reference Values; Sciatic Nerve; Sensation | 2003 |
Suppression of proliferative cholangitis in a rat model by local delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bile Ducts; Cholangitis; Disease Models, Animal; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Paclitaxel; Rats; Rats, Sprague-Dawley | 2003 |
Combined trastuzumab and paclitaxel treatment better inhibits ErbB-2-mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Breast Neoplasms; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Neovascularization, Pathologic; Paclitaxel; Probability; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Reference Values; Trastuzumab; Tumor Cells, Cultured | 2003 |
Role of sensory nerve peptides rather than mast cell histamine in paclitaxel hypersensitivity.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Disease Models, Animal; Drug Hypersensitivity; Histamine; Immunohistochemistry; Infusions, Intravenous; Male; Mast Cells; Neurokinin A; Neuropeptides; Paclitaxel; Probability; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Sensory Receptor Cells; Substance P | 2004 |
Effects of intraperitoneal administration of gemcitabine and paclitaxel on hepatic regeneration in rats.
Topics: Animals; Biopsy, Needle; Deoxycytidine; Disease Models, Animal; Gemcitabine; Hepatectomy; Immunohistochemistry; Injections, Intraperitoneal; Liver; Liver Function Tests; Liver Regeneration; Male; Paclitaxel; Rats; Rats, Inbred Strains; Sensitivity and Specificity | 2003 |
Low-dose irradiation and short-exposure suboptimal-dose paclitaxel adversely modulate metastatic potential of squamous carcinoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Line, Tumor; Colony-Forming Units Assay; Cytoskeleton; Data Interpretation, Statistical; Disease Models, Animal; Humans; Immunohistochemistry; Interphase; Liver Neoplasms; Mice; Mice, SCID; Microscopy, Confocal; Neoplasm Metastasis; Paclitaxel; Radiation-Sensitizing Agents; Radiotherapy Dosage | 2003 |
Effects of epithelial growth factor receptor (EGFR) kinase inhibitors on genetically reconstituted mouse mammary glands.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Transformed; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; ErbB Receptors; Female; Image Cytometry; Injections, Intravenous; Ki-67 Antigen; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Paclitaxel; Protein-Tyrosine Kinases; Treatment Outcome | 2003 |
Paclitaxel-induced neuropathic hypersensitivity in mice: responses in 10 inbred mouse strains.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Cold Temperature; Disease Models, Animal; Female; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Paclitaxel; Pain; Peripheral Nervous System Diseases; Physical Stimulation; Species Specificity | 2004 |
Effect of chemotherapy on primordial follicular reserve of rat: an animal model of premature ovarian failure and infertility.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Infertility, Female; Injections, Intraperitoneal; Ovarian Follicle; Paclitaxel; Primary Ovarian Insufficiency; Probability; Random Allocation; Rats; Reference Values | 2004 |
[Potentiation of focal ultrasound treatment of prostate adenocarcinoma by concomitant chemotherapy with estramustine phosphate and paclitaxel].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Combined Modality Therapy; Disease Models, Animal; Estramustine; Male; Paclitaxel; Prostatic Neoplasms; Rats; Ultrasonic Therapy | 2004 |
Transient receptor potential vanilloid 4 is essential in chemotherapy-induced neuropathic pain in the rat.
Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Calcium; Cation Transport Proteins; Cells, Cultured; Disease Models, Animal; Hyperalgesia; Hypotonic Solutions; Integrins; Ion Channels; Male; Neuralgia; Nociceptors; Oligonucleotides, Antisense; Paclitaxel; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Signal Transduction; src-Family Kinases; TRPV Cation Channels | 2004 |
Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Deoxycytidine; Disease Models, Animal; DNA, Neoplasm; Docetaxel; Doxorubicin; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Epirubicin; Female; Floxuridine; Gemcitabine; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Exchange Factors; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; Paclitaxel; Proto-Oncogene Proteins; Receptor, ErbB-2; Taxoids; Transplantation, Heterologous; Trastuzumab; Tumor Stem Cell Assay; Up-Regulation; Vinblastine; Vinorelbine | 2004 |
Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neu in a murine mammary carcinoma model.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Breast Neoplasms; Cancer Vaccines; Carcinoma; Cell Line; Combined Modality Therapy; Disease Models, Animal; Doxorubicin; Drug Administration Schedule; Epitopes; Female; Humans; Interferon-gamma; Lymphocyte Activation; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Paclitaxel; Receptor, ErbB-2; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic; Vaccines, DNA | 2004 |
Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: biocompatibility and efficacy determinations in rabbits.
Topics: Animals; Arthritis; Biocompatible Materials; Chitosan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Inflammation; Injections, Intra-Articular; Joints; Materials Testing; Microspheres; Paclitaxel; Rabbits; Synovial Fluid; Treatment Outcome | 2004 |
Angiogenesis gene expression profiling in xenograft models to study cellular interactions.
Topics: Angiogenesis Inhibitors; Angiogenic Proteins; Animals; Antineoplastic Agents; Base Sequence; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Mice; Molecular Sequence Data; Neovascularization, Pathologic; Ovarian Neoplasms; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Nucleic Acid; Skin Neoplasms; Transplantation, Heterologous | 2004 |
Efficacy of transferrin-conjugated paclitaxel-loaded nanoparticles in a murine model of prostate cancer.
Topics: Animals; Biocompatible Materials; Disease Models, Animal; Drug Delivery Systems; Male; Mice; Mice, Nude; Nanotechnology; Paclitaxel; Pharmaceutical Vehicles; Polyethylene Glycols; Prostatic Neoplasms; Survival Analysis; Transferrin | 2004 |
Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resista
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cyclooxygenase 2; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Intramolecular Oxidoreductases; Irinotecan; Isoenzymes; Liver Neoplasms; Lung Neoplasms; Membrane Proteins; Mice; Mice, Nude; Neoplasm Proteins; Organoplatinum Compounds; Ornithine Decarboxylase; Oxaliplatin; Paclitaxel; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Survival Rate; Transplantation, Heterologous; Vault Ribonucleoprotein Particles | 2004 |
Antimetastatic and anticancer activity of S-1, a new oral dihydropyrimidine-dehydrogenase-inhibiting fluoropyrimidine, alone and in combination with paclitaxel in an orthotopically implanted human breast cancer model.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease Models, Animal; Drug Combinations; Female; Mice; Mice, SCID; Neoplasm Metastasis; Oxonic Acid; Paclitaxel; Pyridines; Tegafur; Transplantation, Heterologous | 2004 |
Microtubule-stabilising drugs may be therapeutic in AD.
Topics: Alzheimer Disease; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Humans; Microtubules; Paclitaxel; tau Proteins | 2005 |
Use of a tacrolimus-eluting stent to inhibit neointimal hyperplasia in a porcine coronary model.
Topics: Animals; Cell Survival; Coated Materials, Biocompatible; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Immunosuppressive Agents; Male; Paclitaxel; Stents; Swine; Tacrolimus; Tunica Intima | 2005 |
An inhibitor of Bcl-2 family proteins induces regression of solid tumours.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Carcinoma, Small Cell; Cell Line, Tumor; Cytochromes c; Disease Models, Animal; Drug Synergism; Humans; Lymphoma; Magnetic Resonance Spectroscopy; Mice; Mitochondria; Models, Molecular; Neoplasms; Nitrophenols; Paclitaxel; Piperazines; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Sulfonamides; Survival Rate | 2005 |
Spinal glial glutamate transporters downregulate in rats with taxol-induced hyperalgesia.
Topics: Amino Acid Transport System X-AG; Animals; Antineoplastic Agents, Phytogenic; Cell Communication; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hyperalgesia; Male; Neuroglia; Nociceptors; Paclitaxel; Peripheral Nervous System Diseases; Posterior Horn Cells; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Symporters; Synaptic Transmission | 2005 |
Comparative study of tacrolimus and paclitaxel stent coating in the porcine coronary model.
Topics: Animals; Blood Vessel Prosthesis; Coated Materials, Biocompatible; Coronary Restenosis; Coronary Vessels; Delayed-Action Preparations; Disease Models, Animal; Graft Occlusion, Vascular; Immunosuppressive Agents; Paclitaxel; Swine; Swine, Miniature; Tacrolimus; Treatment Outcome | 2005 |
In vivo evaluation of ixabepilone (BMS247550), a novel epothilone B derivative, against pediatric cancer models.
Topics: Animals; Area Under Curve; Brain Neoplasms; Cell Line, Tumor; Clinical Trials as Topic; Disease Models, Animal; Dose-Response Relationship, Drug; Epothilones; Female; Humans; Maximum Tolerated Dose; Mice; Mice, SCID; Microtubules; Mitosis; Models, Chemical; Neoplasm Transplantation; Neuroblastoma; Osteosarcoma; Paclitaxel; Rhabdomyosarcoma; Time Factors; Treatment Outcome; Vinca Alkaloids; Wilms Tumor | 2005 |
Vascular endothelial growth factor trap combined with paclitaxel strikingly inhibits tumor and ascites, prolonging survival in a human ovarian cancer model.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ascites; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Mice; Mice, Nude; Necrosis; Neoplasm Metastasis; Neoplasm Transplantation; Ovarian Neoplasms; Paclitaxel; Time Factors; Treatment Outcome; Vascular Endothelial Growth Factor A | 2005 |
A cannabinoid agonist, WIN 55,212-2, reduces neuropathic nociception induced by paclitaxel in rats.
Topics: Analgesics; Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Benzoxazines; Cannabinoids; Disease Models, Animal; Hot Temperature; Humans; Hyperalgesia; Male; Morpholines; Naphthalenes; Neuralgia; Paclitaxel; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Wistar; Sensory Thresholds; Touch; Treatment Outcome | 2005 |
Role of the antiangiogenetic drug paclitaxel on healing of intestinal anastomosis: an experimental study.
Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Antineoplastic Agents, Phytogenic; Colectomy; Colon; Disease Models, Animal; Injections, Intraperitoneal; Intraoperative Care; Paclitaxel; Probability; Random Allocation; Rats; Rats, Wistar; Sensitivity and Specificity; Statistics, Nonparametric; Tensile Strength; Wound Healing | 2005 |
Enhancement of antitumor effect of paclitaxel in combination with immunomodulatory Withania somnifera on benzo(a)pyrene induced experimental lung cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Disease Models, Animal; Immunoglobulins; Immunologic Factors; Lung Neoplasms; Male; Medicine, Ayurvedic; Mice; Paclitaxel; Phytotherapy; Plant Extracts; Withania | 2006 |
Therapeutic efficacy of prosaposin-derived peptide on different models of allodynia.
Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Diabetes Complications; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Nerve Growth Factors; Paclitaxel; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatica; Skin; Time Factors | 2006 |
[The effect of paclitaxel-eluting stents on restenosis].
Topics: Animals; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Humans; Paclitaxel; Platelet Aggregation Inhibitors; Random Allocation; Secondary Prevention; Stents; Swine; Ticlopidine; Tunica Intima; Ultrasonography, Interventional | 2006 |
Ribonucleic acid interference targeting S100A4 (Mts1) suppresses tumor growth and metastasis of anaplastic thyroid carcinoma in a mouse model.
Topics: Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Paclitaxel; RNA Interference; S100 Calcium-Binding Protein A4; S100 Proteins; Thyroid Neoplasms | 2006 |
Paclitaxel-coated expanded polytetrafluoroethylene haemodialysis grafts inhibit neointimal hyperplasia in porcine model of graft stenosis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arteriovenous Shunt, Surgical; Blood Vessel Prosthesis; Coated Materials, Biocompatible; Disease Models, Animal; Fluorocarbon Polymers; Graft Occlusion, Vascular; Hyperplasia; In Vitro Techniques; Male; Paclitaxel; Prosthesis Design; Renal Dialysis; Swine; Tunica Intima | 2006 |
A novel paclitaxel-eluting porous carbon-carbon nanoparticle coated, nonpolymeric cobalt-chromium stent: evaluation in a porcine model.
Topics: Analysis of Variance; Animals; Carbon; Chromium; Coated Materials, Biocompatible; Cobalt; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Lactic Acid; Nanostructures; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Stents; Swine | 2006 |
Dual epidermal growth factor receptor and vascular endothelial growth factor receptor inhibition with NVP-AEE788 for the treatment of aggressive follicular thyroid cancer.
Topics: Adenocarcinoma, Follicular; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; ErbB Receptors; Humans; Male; Mice; Mice, Nude; Paclitaxel; Phosphorylation; Predictive Value of Tests; Prognosis; Purines; Receptors, Vascular Endothelial Growth Factor; Structure-Activity Relationship; Thyroid Neoplasms; Xenograft Model Antitumor Assays | 2006 |
Effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in combination with paclitaxel (Taxol) on prostate Cancer LNCaP cells cultured in vitro or grown as xenograft tumors in immunodeficient mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Humans; Injections, Intraperitoneal; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Nude; Mice, SCID; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Treatment Outcome; Xenograft Model Antitumor Assays | 2006 |
Preclinical pharmacologic evaluation of MST-997, an orally active taxane with superior in vitro and in vivo efficacy in paclitaxel- and docetaxel-resistant tumor models.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Binding Sites; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; In Situ Hybridization, Fluorescence; Injections, Intravenous; Mice; Mice, Nude; Molecular Conformation; Paclitaxel; Stereoisomerism; Taxoids; Tubulin; Xenograft Model Antitumor Assays | 2006 |
Silica-induced apoptosis in alveolar macrophages: evidence of in vivo thiol depletion and the activation of mitochondrial pathway.
Topics: Acetylcysteine; Alkaloids; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzylisoquinolines; Caspase 3; Caspases; Cysteine; Cytochromes c; Disease Models, Animal; Glutathione; Inflammation Mediators; Macrophages, Alveolar; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; Oxidative Stress; Paclitaxel; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Silicon Dioxide; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha | 2006 |
Perivascular paclitaxel wraps block arteriovenous graft stenosis in a pig model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arteriovenous Shunt, Surgical; Disease Models, Animal; Drug Implants; Graft Occlusion, Vascular; Paclitaxel; Swine; Treatment Outcome | 2006 |
Synergistic antitumor activity of taxol and immunotoxin SS1P in tumor-bearing mice.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Humans; Injections, Intraperitoneal; Injections, Subcutaneous; Mesothelin; Mice; Mice, Nude; Paclitaxel; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2006 |
NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel.
Topics: Animals; Collagen Type III; Disease Models, Animal; Female; Humans; Lung; Lung Neoplasms; Mice; Mice, Inbred C57BL; Paclitaxel; Radiation-Sensitizing Agents; Rats; Rats, Inbred Lew | 2006 |
A mouse model for the molecular characterization of brca1-associated ovarian carcinoma.
Topics: Animals; BRCA1 Protein; Cell Transformation, Neoplastic; Cisplatin; Disease Models, Animal; DNA Damage; Epithelial Cells; Female; Genes, BRCA1; Genes, myc; Genes, p53; Mice; Mice, Transgenic; Ovarian Neoplasms; Ovary; Paclitaxel; Proto-Oncogene Proteins c-myc; Tumor Suppressor Protein p53 | 2006 |
Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells.
Topics: Activating Transcription Factor 3; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents, Phytogenic; CD11b Antigen; Chemotaxis, Leukocyte; Disease Models, Animal; Ganglia, Spinal; Glial Fibrillary Acidic Protein; Hyperalgesia; Injections, Intravenous; Macrophages; Male; Microglia; Neurons, Afferent; Paclitaxel; Peripheral Nerves; Peripheral Nervous System Diseases; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Satellite Cells, Perineuronal; Schwann Cells | 2007 |
Paclitaxel delivered to adventitia attenuates neointima formation without compromising re-endothelialization after angioplasty in a porcine restenosis model.
Topics: Analysis of Variance; Angioplasty, Balloon; Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; Connective Tissue; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Femoral Artery; Fluorescent Antibody Technique; Graft Occlusion, Vascular; Hyperplasia; Immunohistochemistry; Injections, Intra-Arterial; Ki-67 Antigen; Myocytes, Smooth Muscle; Paclitaxel; Platelet Endothelial Cell Adhesion Molecule-1; Research Design; Reverse Transcriptase Polymerase Chain Reaction; Swine; Tunica Intima; Tunica Media; von Willebrand Factor | 2006 |
Chemotherapy-evoked painful peripheral neuropathy: analgesic effects of gabapentin and effects on expression of the alpha-2-delta type-1 calcium channel subunit.
Topics: Amines; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Male; Motor Activity; Neuralgia; Paclitaxel; Pain Measurement; Protein Subunits; Rats; Rats, Sprague-Dawley; Time Factors; Vincristine | 2007 |
Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases reduces growth and metastasis of human salivary adenoid cystic carcinoma in an orthotopic nude mouse model.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Adenoid Cystic; Cisplatin; Disease Models, Animal; ErbB Receptors; Humans; Male; Mice; Mice, Nude; Neoplasm Metastasis; Oncogene Protein v-akt; Paclitaxel; Parotid Gland; Phosphorylation; Purines; Salivary Gland Neoplasms; Taxoids; Vascular Endothelial Growth Factor Receptor-2 | 2006 |
Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; CD11b Antigen; Cytokines; Disease Models, Animal; Ganglia, Spinal; Genetic Therapy; Hyperalgesia; Injections, Spinal; Interleukin-10; Interleukin-1beta; Male; Meninges; Neuroglia; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Plasmids; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; RNA, Messenger; Spinal Cord; Tumor Necrosis Factor-alpha | 2007 |
Modified paclitaxel-loaded nanoparticles for inhibition of hyperplasia in a rabbit arterial balloon injury model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carotid Artery Injuries; Catheterization; Chromatography, High Pressure Liquid; Diffusion; Disease Models, Animal; Endothelium, Vascular; Hyperplasia; Microscopy, Electron, Transmission; Nanoparticles; Paclitaxel; Particle Size; Polyglactin 910; Polyvinyl Alcohol; Rabbits; Solubility; Time Factors; Treatment Outcome; Tunica Intima | 2007 |
Coating with paclitaxel improves graft survival in a porcine model of haemodialysis graft stenosis.
Topics: Animals; Coated Materials, Biocompatible; Constriction, Pathologic; Disease Models, Animal; Graft Rejection; Graft Survival; Male; Paclitaxel; Polytetrafluoroethylene; Prosthesis Design; Renal Dialysis; Swine; Time Factors; Tubulin Modulators | 2007 |
Paclitaxel in the treatment of retinal tumors of LH beta-Tag murine transgenic model of retinoblastoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Conjunctiva; Disease Models, Animal; Injections, Intralesional; Linear Models; Luteinizing Hormone, beta Subunit; Mice; Mice, Transgenic; Paclitaxel; Retinal Neoplasms; Retinoblastoma | 2007 |
Nucleolar enlargement, nuclear eccentricity and altered cell body immunostaining characteristics of large-sized sensory neurons following treatment of rats with paclitaxel.
Topics: Activating Transcription Factor 3; Animals; Antineoplastic Agents, Phytogenic; Cell Nucleolus; Cell Size; Disease Models, Animal; Female; Ganglia, Spinal; H-Reflex; Immunohistochemistry; Neural Conduction; Neurons, Afferent; Neuropeptide Y; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nervous System Diseases; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Reaction Time; Up-Regulation | 2007 |
Molecular mechanisms of paclitaxel and NM-3 on human gastric cancer in a severe combined immune deficiency mice orthotopic implantation model.
Topics: Adenocarcinoma; Animals; Antigens, Viral, Tumor; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Humans; Isocoumarins; Male; Mice; Mice, Nude; Mice, SCID; Paclitaxel; Stomach Neoplasms; Viral Core Proteins; Xenograft Model Antitumor Assays | 2007 |
Inhibition of pseudointimal hyperplasia in swine TIPS models: the efficacy of local delivery of paclitaxel using a perforated balloon catheter.
Topics: Angioplasty, Balloon; Animals; Antineoplastic Agents, Phytogenic; Catheterization; Disease Models, Animal; Drug Delivery Systems; Hepatic Veins; Hyperplasia; Paclitaxel; Portasystemic Shunt, Transjugular Intrahepatic; Swine; Treatment Outcome | 2007 |
Pimecrolimus and dual pimecrolimus-paclitaxel eluting stents decrease neointimal proliferation in a porcine model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Vessel Prosthesis Implantation; Calcineurin Inhibitors; Cell Proliferation; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug Combinations; Follow-Up Studies; Graft Occlusion, Vascular; Immunosuppressive Agents; Paclitaxel; Stents; Swine; Tacrolimus; Treatment Outcome; Tunica Intima | 2007 |
Comparison of intraperitoneal with intravenous administration of taxol in experimental peritoneal carcinomatosis.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Injections, Intraperitoneal; Injections, Intravenous; Liver Neoplasms, Experimental; Male; Paclitaxel; Peritoneal Neoplasms; Rats; Rats, Inbred ACI; Rats, Inbred Strains | 2007 |
Anti-inflammatory effect of abciximab-coated stent in a porcine coronary restenosis model.
Topics: Abciximab; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Arteries; Constriction, Pathologic; Coronary Restenosis; Disease Models, Animal; Drug-Eluting Stents; Female; Hyperplasia; Immunoglobulin Fab Fragments; Inflammation; Paclitaxel; Sirolimus; Swine; Tunica Intima | 2007 |
Dual drug release from stents-will we be happy with thing one and thing two?
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Vessel Prosthesis Implantation; Calcineurin Inhibitors; Cell Proliferation; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug Combinations; Graft Occlusion, Vascular; Immunosuppressive Agents; Paclitaxel; Stents; Swine; Tacrolimus; Treatment Outcome | 2007 |
Application of paclitaxel-eluting metal stents in renal artery of pig model.
Topics: Angiography; Angioscopy; Animals; Antineoplastic Agents, Phytogenic; Blood Vessel Prosthesis Implantation; Coated Materials, Biocompatible; Disease Models, Animal; Female; Paclitaxel; Prosthesis Design; Renal Artery Obstruction; Stents; Swine; Treatment Outcome | 2007 |
Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-L-carnitine: effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells.
Topics: Acetylcarnitine; Animals; Axons; Behavior, Animal; Disease Models, Animal; Drug Interactions; Langerhans Cells; Male; Microscopy, Electron, Transmission; Mitochondria; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Skin | 2008 |
Short- and long-term effects of a novel paclitaxel coated stent in the porcine coronary model.
Topics: Angioplasty, Balloon, Coronary; Animals; Coronary Angiography; Coronary Disease; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Follow-Up Studies; Paclitaxel; Probability; Random Allocation; Risk Factors; Survival Rate; Swine; Swine, Miniature; Time Factors; Treatment Outcome | 2008 |
Paclitaxel associated with cholesterol-rich nanoemulsions promotes atherosclerosis regression in the rabbit.
Topics: Animals; Anticholesteremic Agents; Aorta, Thoracic; Atherosclerosis; Cholesterol; Disease Models, Animal; Drug Delivery Systems; Emulsions; Male; Paclitaxel; Rabbits | 2008 |
Inflammation and delayed endothelization with overlapping drug-eluting stents in a porcine model of in-stent restenosis.
Topics: Animals; Cell Proliferation; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Endothelium, Vascular; Female; Hyperplasia; Inflammation; Paclitaxel; Sirolimus; Stents; Swine; Tunica Intima | 2008 |
High energy shock waves (HESW) increase paclitaxel efficacy in a syngeneic model of breast cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-Associated Death Protein; Breast Neoplasms; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Female; Gene Expression; High-Energy Shock Waves; In Situ Nick-End Labeling; Paclitaxel; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Imaging paclitaxel (chemotherapy)-induced tumor apoptosis with 99mTc C2A, a domain of synaptotagmin I: a preliminary study.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Disease Models, Animal; DNA Fragmentation; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Mice; Paclitaxel; Protein Structure, Tertiary; Radioligand Assay; Radionuclide Imaging; Radiopharmaceuticals; Synaptotagmin I; Technetium; Tissue Distribution | 2008 |
Cures for polycystic kidney diseases?
Topics: Animals; Disease Models, Animal; Humans; Paclitaxel; Polycystic Kidney Diseases | 1994 |
Taxol inhibits progression of congenital polycystic kidney disease.
Topics: Animals; Body Weight; Cells, Cultured; Disease Models, Animal; Humans; Kidney; Mice; Microtubules; Organ Size; Paclitaxel; Polycystic Kidney Diseases | 1994 |
Regression of collagen-induced arthritis with taxol, a microtubule stabilizer.
Topics: Animals; Antibodies; Arthritis; Collagen; Disease Models, Animal; Female; Immunoglobulin G; Paclitaxel; Radiography; Rats; Remission Induction; Synovial Membrane | 1994 |
Application of the ATP-cell viability assay for assessment of in vitro radiation treatment response in gynecologic cancer cell lines.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Combined Modality Therapy; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Screening Assays, Antitumor; Female; Ovarian Neoplasms; Paclitaxel; Radiation Tolerance; Radiotherapy Dosage; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1994 |
The antitumoral effect of the immunomodulator AS101 and paclitaxel (Taxol) in a murine model of lung adenocarcinoma.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cytotoxicity, Immunologic; Disease Models, Animal; Drug Therapy, Combination; Ethylenes; Female; Lung Neoplasms; Macrophage Activation; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nitric Oxide; Paclitaxel; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1996 |
Effect of the microtubule-disrupting drug colchicine on rat cerulein-induced pancreatitis in comparison with the microtubule stabilizer taxol.
Topics: Acute Disease; Amylases; Animals; Ceruletide; Colchicine; Disease Models, Animal; Gastrointestinal Agents; Male; Microscopy, Electron; Microscopy, Fluorescence; Microtubules; Paclitaxel; Pancreatic Juice; Pancreatitis; Rats; Rats, Wistar; Trypsin; Tubulin | 1995 |
Skin ulceration potential of paclitaxel in a mouse skin model in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dose-Response Relationship, Drug; Extravasation of Diagnostic and Therapeutic Materials; Female; Injections, Intradermal; Mice; Mice, Inbred BALB C; Paclitaxel; Skin Ulcer | 1996 |
Effects of amifostine and paclitaxel on growth of human ovarian carcinoma xenografts in the severe combined immune-deficient mouse: preliminary results.
Topics: Amifostine; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Mice; Mice, SCID; Ovarian Neoplasms; Paclitaxel; Radiation-Protective Agents; Tumor Cells, Cultured | 1996 |
Acute in vivo resistance in high-dose therapy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cyclophosphamide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Mammary Neoplasms, Experimental; Melphalan; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Paclitaxel; Thiotepa | 1998 |
Taxol involution of collagen-induced arthritis: ultrastructural correlation with the inhibition of synovitis and neovascularization.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arthritis, Rheumatoid; Collagen; Corrosion Casting; Disease Models, Animal; Female; Humans; Microscopy, Electron; Microscopy, Electron, Scanning; Neovascularization, Pathologic; Paclitaxel; Rats; Rats, Inbred Strains; Synovial Membrane; Synovitis | 1998 |
Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer.
Topics: Adenoviridae; Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Combined Modality Therapy; Disease Models, Animal; Drug Synergism; Female; Gene Transfer Techniques; Genes, p53; Genetic Therapy; Genetic Vectors; Head and Neck Neoplasms; Humans; Male; Mammary Neoplasms, Animal; Mice; Microtubules; Neoplasms; Ovarian Neoplasms; Paclitaxel; Prostatic Neoplasms; Transduction, Genetic; Treatment Outcome; Tumor Cells, Cultured | 1998 |
Cyclosporin A enhances paclitaxel toxicity against leukemia and respiratory epithelial cancers.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclosporine; Cytokines; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Glycerol; Growth Substances; Humans; Immunosuppressive Agents; Leukemia; Mice; Paclitaxel; Respiratory Tract Neoplasms; Survival Rate; Treatment Outcome; Tumor Cells, Cultured | 1997 |
Simultaneous genetic chemoprotection of normal marrow cells and genetic chemosensitization of breast cancer cells in a mouse cancer gene therapy model.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Chemoprevention; Disease Models, Animal; DNA, Complementary; Drug Resistance, Neoplasm; Female; Genetic Therapy; Humans; Mammary Neoplasms, Animal; Metallothionein; Mice; Mice, Inbred BALB C; Paclitaxel; Promoter Regions, Genetic; Retroviridae; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1997 |
Tyrosine kinase inhibitor emodin suppresses growth of HER-2/neu-overexpressing breast cancer cells in athymic mice and sensitizes these cells to the inhibitory effect of paclitaxel.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Division; Disease Models, Animal; Drug Synergism; Emodin; Enzyme Inhibitors; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Receptor, ErbB-2; Tumor Cells, Cultured; Tyrosine | 1999 |
Paclitaxel: an effective antineoplastic agent in the treatment of xenotransplanted hepatoblastoma.
Topics: alpha-Fetoproteins; Animals; Antibodies; Antineoplastic Agents, Phytogenic; Cell Division; Child, Preschool; Disease Models, Animal; Female; Hepatoblastoma; Humans; Immunohistochemistry; Infant; Liver Neoplasms; Mice; Mice, Nude; Paclitaxel; Transplantation, Heterologous; Tubulin | 1999 |
The common marmoset as a target preclinical primate model for cytokine and gene therapy studies.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Callithrix; Cells, Cultured; Cytokines; Disease Models, Animal; DNA, Viral; Docetaxel; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Granulocyte Colony-Stimulating Factor; Granulocytes; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Lymphocytes; Paclitaxel; Polymerase Chain Reaction; Retroviridae; Stromal Cells; Taxoids; Transplantation, Autologous | 1999 |
Synthesis of taxoids 5. Synthesis and evaluation of novel water-soluble prodrugs of a 3'-desphenyl-3'-cyclopropyl analogue of docetaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Docetaxel; Drug Screening Assays, Antitumor; Humans; Melanoma, Experimental; Mice; Neoplasm Transplantation; Paclitaxel; Prodrugs; Solubility; Structure-Activity Relationship; Taxoids; Transplantation, Heterologous; Tumor Cells, Cultured; Water | 1999 |
Marked antiangiogenic and antitumor efficacy of AG3340 in chemoresistant human non-small cell lung cancer tumors: single agent and combination chemotherapy studies.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Drug Interactions; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Organic Chemicals; Paclitaxel; Transplantation, Heterologous; Treatment Outcome; Tumor Cells, Cultured | 1999 |
Inhalation chemotherapy for macroscopic primary or metastatic lung tumors: proof of principle using dogs with spontaneously occurring tumors as a model.
Topics: Administration, Inhalation; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dog Diseases; Dogs; Doxorubicin; Female; Lung Neoplasms; Male; Melanoma; Paclitaxel; Sarcoma | 1999 |
Biological and pharmacological characterisation of three models of human ovarian carcinoma established in nude mice: use of the CA125 tumour marker to predict antitumour activity.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; CA-125 Antigen; Cisplatin; Disease Models, Animal; Female; Humans; Mice; Mice, Congenic; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Paclitaxel; Survival Analysis; Transplantation, Heterologous; Tumor Cells, Cultured | 1999 |
Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides.
Topics: Androgens; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Male; Mammary Neoplasms, Experimental; Mice; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Oligonucleotides, Antisense; Paclitaxel; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm | 2000 |
Enhancement of paclitaxel delivery to solid tumors by apoptosis-inducing pretreatment: effect of treatment schedule.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Count; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Paclitaxel; Tritium; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2001 |
Calcitriol (1,25-dihydroxycholecalciferol) enhances paclitaxel antitumor activity in vitro and in vivo and accelerates paclitaxel-induced apoptosis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Calcitriol; Calcium Channel Agonists; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression; Mice; Paclitaxel; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2001 |
Schedule dependency of antitumor activity in combination therapy with capecitabine/5'-deoxy-5-fluorouridine and docetaxel in breast cancer models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Deoxycytidine; Disease Models, Animal; Docetaxel; Drug Administration Schedule; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Paclitaxel; Taxoids; Thymidine Phosphorylase; Tumor Cells, Cultured; Up-Regulation; Xenograft Model Antitumor Assays | 2001 |
Paclitaxel stent coating inhibits neointimal hyperplasia at 4 weeks in a porcine model of coronary restenosis.
Topics: Animals; Coronary Angiography; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Graft Occlusion, Vascular; Hyperplasia; Infusion Pumps, Implantable; Male; Paclitaxel; Stents; Surface Properties; Swine, Miniature; Tunica Intima | 2001 |
BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Survival; Colonic Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Epothilones; Epoxy Compounds; Female; Humans; Infusions, Parenteral; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Ovarian Neoplasms; Paclitaxel; Pancreatic Neoplasms; Sarcoma; Thiazoles; Tubulin; Tumor Cells, Cultured; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2001 |
A preclinical model for experimental chemotherapy of human head and neck cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Body Weight; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Disease Models, Animal; Docetaxel; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Ifosfamide; Methotrexate; Mice; Mice, Nude; Paclitaxel; Survival Rate; Taxoids | 2001 |
Use of antisense oligonucleotides targeting the antiapoptotic gene, clusterin/testosterone-repressed prostate message 2, to enhance androgen sensitivity and chemosensitivity in prostate cancer.
Topics: Androgen Antagonists; Animals; Antineoplastic Agents, Hormonal; Apoptosis; Calcium Channel Blockers; Cell Death; Clusterin; Disease Models, Animal; Drug Synergism; Glycoproteins; Humans; Male; Mice; Molecular Chaperones; Neoadjuvant Therapy; Oligonucleotides, Antisense; Orchiectomy; Paclitaxel; Prostatic Neoplasms; Up-Regulation; Xenograft Model Antitumor Assays | 2001 |
Leukaemia inhibitory factor abrogates Paclitaxel-induced axonal atrophy in the Wistar rat.
Topics: Animals; Antineoplastic Agents, Phytogenic; Axons; Calcitonin Gene-Related Peptide; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Spinal; Growth Inhibitors; Immunohistochemistry; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Nerve Degeneration; Neural Conduction; Neurons, Afferent; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Substance P | 2001 |
Local delivery of paclitaxel using the double-balloon perfusion catheter before stenting in the porcine coronary artery.
Topics: Angioplasty, Balloon; Animals; Antineoplastic Agents, Phytogenic; Catheterization; Coronary Vessels; Disease Models, Animal; Drug Delivery Systems; Electrocardiography; Infusion Pumps; Paclitaxel; Stents; Swine | 2001 |
VIP receptor antagonists and chemotherapeutic drugs inhibit the growth of breast cancer cells.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cyclic AMP; Disease Models, Animal; Doxorubicin; Drug Synergism; Female; Genes, fos; Humans; Iodine Radioisotopes; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neurotensin; Paclitaxel; Protein Binding; Receptors, Vasoactive Intestinal Peptide; Recombinant Fusion Proteins; RNA, Messenger; Thymidine; Transplantation, Heterologous; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 2001 |
Paclitaxel-coated Gianturco-Roubin II (GR II) stents reduce neointimal hyperplasia in a porcine coronary in-stent restenosis model.
Topics: Angiogenesis Inhibitors; Animals; Coronary Angiography; Coronary Vessels; Disease Models, Animal; Graft Occlusion, Vascular; Hyperplasia; Paclitaxel; Stents; Swine; Tunica Intima | 2001 |
A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Cold Temperature; Disease Models, Animal; Hindlimb; Hot Temperature; Hyperalgesia; Male; Motor Activity; Paclitaxel; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Tail | 2001 |
Inhibition of phosphatidylinositol 3'-kinase increases efficacy of paclitaxel in in vitro and in vivo ovarian cancer models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Division; Chromones; Disease Models, Animal; Drug Synergism; Enzyme Inhibitors; Female; Humans; Mice; Mice, Nude; Morpholines; Ovarian Neoplasms; Paclitaxel; Phosphoinositide-3 Kinase Inhibitors; Tumor Cells, Cultured | 2002 |
HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Endothelial Growth Factors; Endothelium, Vascular; Extraembryonic Membranes; Female; Fibroblast Growth Factor 2; HIV Protease Inhibitors; Humans; Indinavir; Lymphokines; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Paclitaxel; Saquinavir; Sarcoma, Kaposi; Skin; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Combined modality radioimmunotherapy. Promise and peril.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Cetuximab; Combined Modality Therapy; Disease Models, Animal; Female; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Mice, Nude; Mortality; Neoplasm Transplantation; Neoplasms, Experimental; Oligopeptides; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Radioimmunotherapy; Radiotherapy; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2002 |
Pharmacokinetics of paclitaxel administered by hyperthermic retrograde isolated lung perfusion techniques.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Bronchi; Chemotherapy, Cancer, Regional Perfusion; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Hyperthermia, Induced; Infusions, Intravenous; Lung Neoplasms; Paclitaxel; Sheep; Treatment Outcome; Tumor Cells, Cultured | 2002 |
A mouse model for the study of factors affecting angiogenesis.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Docetaxel; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Humans; Ifosfamide; Injections, Subcutaneous; Mice; Neovascularization, Pathologic; Paclitaxel; Prostheses and Implants; Surgical Sponges; Taxoids | 2002 |
Polysaccharide of
Topics: Alzheimer Disease; Animals; Apoptosis; Cell Line; Cell Survival; Cognitive Dysfunction; Disease Models, Animal; Dose-Response Relationship, Drug; Galactose; Maze Learning; Mice; Mice, Inbred C57BL; Oxidative Stress; Polysaccharides; Taxus | 2020 |
Anti-inflammatory activities of Taxusabietane A isolated from Taxus wallichiana Zucc.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Edema; Female; Flavanones; Lipoxygenase Inhibitors; Male; Phenanthrenes; Phytotherapy; Plant Bark; Plant Extracts; Rats; Rats, Wistar; Taxus | 2011 |
Control of hypertension in rats using volatile components of leaves of Taxus chinensis var. mairei.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Chromatography, Supercritical Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hydrochlorothiazide; Hypertension; Lipids; Male; Nitric Oxide; Nitroarginine; Phytotherapy; Plant Leaves; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Taxus; Time Factors; Volatilization | 2012 |
Hypertonic sodium bicarbonate for Taxus media-induced cardiac toxicity in swine.
Topics: Animals; Blood Pressure; Calcium; Disease Models, Animal; Electrocardiography; Heart Rate; Hydrogen-Ion Concentration; Hypertonic Solutions; Infusions, Intravenous; Male; Mannitol; Poisoning; Potassium; Sodium; Sodium Bicarbonate; Swine; Taxus | 2002 |
Design and synthesis of novel anti-hyperalgesic agents based on 6-prenylnaringenin as the T-type calcium channel blockers.
Topics: Action Potentials; Analgesics; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; Drug Design; Flavonoids; HEK293 Cells; Humans; Inhibitory Concentration 50; Male; Mice; Neuralgia; Patch-Clamp Techniques; Structure-Activity Relationship | 2018 |