Page last updated: 2024-08-23

paclitaxel and Disease Models, Animal

paclitaxel has been researched along with Disease Models, Animal in 572 studies

Research

Studies (572)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's26 (4.55)18.2507
2000's126 (22.03)29.6817
2010's337 (58.92)24.3611
2020's83 (14.51)2.80

Authors

AuthorsStudies
Fairchild, C; Johnston, K; Kadow, JF; Lee, FL; Long, BH; Rose, WC; Vyas, DM; Wittman, MD1
Chai, H; Cordell, GA; Farnsworth, NR; Hollingshead, MG; Kardono, LB; Kinghorn, AD; Lantvit, D; Lee, IS; Mayo, JG; Mi, Q; Ngassapa, O; Peraza-Sánchez, S; Pezzuto, JM; Reyes-Lim, E; Riswan, S; Zhao, W1
Cai, S; Han, H; Jiang, J; Jiang, W; Jiang, X; Larrick, JW; Li, L; Tian, Z; Wang, Y; Wright, SC; Xiao, Y; Zhang, Z1
Akiyama, T; Bastow, KF; Cragg, G; Fujitake, M; Goto, M; Hung, MC; Kim, Y; Lai, CY; Lang, JY; Lee, EY; Lee, KH; Morris-Natschke, SL; Nakagawa-Goto, K; Newman, DJ; Sakurai, N; Takeya, K; Taniguchi, M; Usami, Y1
Carlson, EM; Cheng, H; Condon, K; Du, H; Eckley, S; Hu, Y; Jiang, Y; Kumar, V; Lewis, BM; Littlefield, BA; Narayan, S; Saxton, P; Schuck, E; Seletsky, BM; Tendyke, K; Towle, MJ; Yu, MJ; Zhang, H; Zheng, W1
Christodoulou, MS; Colombo, F; De Cesare, M; Ieronimo, G; Passarella, D; Zuco, V; Zunino, F1
Cichewicz, RH; Du, L; King, JB; Mooberry, SL; Robles, AJ1
Babaev, VM; Belenok, MG; Kataev, VE; Mironov, VF; Rizvanov, IKh; Semenov, VV; Semenova, MN; Strobykina, IY1
Dymock, BW; Kitagawa, M; Lee, KH; Lee, SH; Liao, PJ; See, CS; Wong, J1
Gu, Y; Hu, L; Liu, Y; Sun, L; Wu, Y1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
An, R; Guo, C; Guo, MB; Hou, Z; Mou, YH; Wang, X; Xu, H; Yan, ZZ; Zhang, R1
Chen, JP; Chen, N; Ge, MM; Li, DY; Liu, DQ; Tian, YK; Wang, XM; Ye, DW; Zhou, YQ1
Koizumi, S; Komatsu, R; Mizuno, K; Shibata, K; Takanashi, K1
Liang, M; Ma, X; Sun, ZJ; Xiao, Y; Xu, Z; Yang, LL; Yang, QC; Yang, SC; Zhang, T1
Cortez, IL; Cunha, TM; Dos Santos, JC; Gomes, FIF; Gomes, FV; Guimarães, FS; Lopes, AHP; Mechoulam, R; Silva, CEA; Silva, NR1
Ali, MY; Ebeid, K; Griguer, C; Naguib, Y; Oliva, C; Quarterman, JC; Salem, AK; Wiwatchaitawee, K1
Aicher, SA; Blum, C; Hamity, MV; Hammond, DL; Hegarty, DM; Kolker, SJ; Langmack, L1
Abi Jaoude, J; Delahoussaye, AM; Feng, N; Fowlkes, N; Fujimoto, TN; Garcia Garcia, CJ; Gay, JP; Green, M; Marszalek, J; Molkentine, J; Taniguchi, CM1
Chen, T; He, Y; Lu, H; Pang, Z; Wang, Y1
Avella, DM; Chaudhuri, AA; Kaifi, JT; Kimchi, ET; Li, G; Manjunath, Y; Mitchem, JB; Nussbaum, YI; Pantel, K; Radhakrishnan, V; Shyu, CR; Staveley-O'Carroll, KF; Suvilesh, KN; Warren, WC1
Bao, S; Cai, J; Jin, Y; Wu, D1
Carvalho, PO; Costalonga, EC; Maranhão, RC; Noronha, IL; Pepineli, R; Silva, FMO1
Akbari, V; Emami, J; Hejazi, E; Lavasanifar, A; Minaiyan, M; Rezazadeh, M1
Cavalli, J; Cristina Dalazen Gonçalves, E; Daniele Bobermin, L; de Assis, PM; Dutra, RC; Gomez, MV; Quincozes-Santos, A; Raposo, NRB1
Bharti, S; Dhiman, S; Goswami, A; Manhas, D; Mir, KB; Nandi, U; Sharma, DK; Tripathi, N; Wazir, P1
Han, H; Healey, AJ; Kvåle, S; Ng, S; Sontum, PC; Sulheim, E; Torp, SH; Von Hoff, D1
Choi, SK; Hwang, SY; Jeon, S; Kwon, Y; Lee, J; Lee, YS; Na, Y; Shin, JH; Yoo, H1
Cai, J; Chen, J; Huang, C; Li, C; Li, M; Wang, B; Wang, J; Zhang, JV; Zhang, P; Zhou, W1
Tian, H; Wang, L; Zhang, Z1
Dong, P; Geng, Q; Liu, N; Wang, HM; Yang, JY; Zhang, Y1
Chu, T; Han, B; Lou, Y; Lu, J; Wang, H; Zhang, W; Zhang, X; Zhang, Y; Zhong, H; Zhong, R1
Jin, Z; Ma, X; Ni, R; Pan, Y; Wu, Q; Yang, G1
Ahire, C; Balasubramanian, P; Campisi, J; Csipo, T; Csiszar, A; DelFavero, J; Faakye, JA; Gulej, R; Kiss, T; Kuan-Celarier, A; Mukli, P; Nagaraja, R; Nyul-Toth, A; Tang, Q; Tarantini, A; Tarantini, S; Ungvari, A; Ungvari, Z; Yabluchanskiy, A; Yan, F1
Allard, J; Bellina, M; Bernet, A; Blanpain, C; Braissand, N; Cassier, PA; Dalban, C; Decaestecker, C; Degletagne, C; Delord, JP; Devouassoux-Shisheboran, M; Dolcet, X; Ducarouge, B; Fattet, L; Gadot, N; Garin, G; Gheit, H; Hernandez-Vargas, H; Jelin, R; Lengrand, J; Léon, S; Matias-Guiu, X; Mehlen, P; Mery-Lamarche, E; Navaridas, R; Neves, D; Paradisi, A; Pastushenko, I; Perol, D; Rama, N; Ray-Coquard, I; Salmon, I; Zindy, E1
Dadey, DY; Fitzpatrick, J; Hallahan, DE; Kapoor, V; Rau, MJ; Saikia, M; Shah, HK; Singh, AK; Thotala, D; Townsend, R1
Adir, O; Alyan, M; Binenbaum, Y; Dvir, T; Fridman, E; Gibori, H; Gil, Z; Hershkovitz, D; Kasten, S; Koren, L; Krayem, M; Krinsky, N; Liba, L; Lübtow, MM; Luxenhofer, R; Milman, N; Mumblat, Y; Noor, N; Ofir, S; Poley, M; Satchi-Fainaro, R; Schroeder, A; Shainsky-Roitman, J; Shklover, J; Simon, A; Yaari, Z; Zinger, A1
Anderson, JA; Engebretson, D; Evans, R; Fuglsby, K; Kelly, P; Lamichhane, S; Pohlson, K; Remund, T1
Gao, M; Jiang, C; Jin, Q; Wang, F; Yao, N; Zhang, D; Zhang, J1
Falah, M; Rayan, A; Rayan, M1
Han, JY; Li, CY; Li, GQ; Li, XL; Liang, AH; Liu, SY; Pan, C; Tian, JZ; Wang, LM; Xian, Z; Yi, Y; Zhang, YS; Zhao, Y1
Gao, X; Ma, Y; Qian, J; Qian, Q; Shi, L; Yang, J; Zhang, Z; Zhu, X1
Chu, K; Han, L; Li, T; Ouyang, H; Qiu, L; Wang, X; Xu, W; Zhang, X1
Abd-Elrazek, AM; El-Dash, HA; Said, NI1
Figg, WD; Kindrick, J; Li, M; Nguyen, L; Peer, CJ; Rajaputra, P; Subramaniyan, B; Woo, S; You, Y1
Byrne, M; Byron, K; Chen, YC; Dear, AE; Gaspari, TA; Kaye, DM; Liu, H; Ozcelik, B; Perlmutter, P; Sama, GR; Subbiah, J; Walker, A; Widdop, RE1
Adamson, T; Borneman, J; Cantin, EM; Corleto, J; Ermel, R; Logan, GD; McKemy, D; Mendonca, S; Peacock, BB; Ramakrishna, C; Ruegger, PM; Yamaki, S1
Baker, D; Cole, T; Faccio, R; Faget, DV; Luo, X; Monahan, J; Murali, B; Ren, Q; Ricci, B; Schwarz, JK; Stewart, SA; Thotala, D; van Deursen, JM; Yao, Z1
Elibol, B; Kilic, U; Orhan, C; Ozercan, IH; Qazi, S; Sahin, K; Sahin, TK; Tuzcu, M; Uckun, FM1
Chu, NQ; Colby, A; Colson, YL; de Forcrand, C; Grinstaff, MW; Liu, R; Padera, RF1
Chen, X; Fu, Y; Gong, T; Hu, Y; Wang, M; Yu, R; Zhang, ZR1
Bai, XH; Deng, J; Ding, HH; Liu, M; Luo, DX; Mai, JW; Ruan, XC; Xin, WJ; Xu, T; Yang, YL; Zhang, SB; Zhang, XQ; Zhang, XZ1
Gong, Y; Huang, P; Liu, H; Ren, X; Wang, J; Weng, M; Yang, X; Yu, Z; Zheng, L; Zheng, Q1
Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; 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Abella, BS; Brinker, JA; Bunge, KE; Cheng, L; Froehlich, JP; Heldman, AW; Heller, PF; Hruban, RH; Hunter, WL; Jenkins, GM; Kim, DW; Kinsella, JL; Lakatta, EG; Nater, C; Rezai, B; Sollott, SJ; Ware, M1
Borzilleri, R; Fairchild, CR; Kim, SH; Kramer, RA; Lee, FY; Long, BH; Reventos-Suarez, C; Rose, WC; Vite, GD1
Bittner, C; Feyerabend, T; Peters, SO; Raap, M; Remmert, S; Robins, IH; Sieg, P; Sommer, K; Wiedemann, GJ1
Chi, K; Gleave, ME; July, L; Miyake, H; Nelson, C; Rennie, P; Zellweger, T1
Cheema, SS; Kilpatrick, TJ; Lopes, EC; Phan, S; Reardon, K1
Al Ghobainy, R; Baumbach, A; Cetin, S; Herdeg, C; Horch, B; Karsch, KR; Küttner, A; Oberhoff, M1
Brenneman, DC; Chan, D; Fridkin, M; Gelber, E; Gozes, I; Levy, A; Leyton, J; Moody, TW1
Bramwell, O; Hong, MK; Kornowski, R; Leon, MB; Ragheb, AO1
Bennett, GJ; Clark, US; Mannes, AJ; Polomano, RC1
Hofmann, J; Hu, L; Jaffe, RB; Lu, Y; Mills, GB1
Baccarini, S; Bacigalupo, I; Barillari, G; Bugarini, R; Bussolino, F; Cafaro, A; Carlei, D; Ensoli, B; Falchi, M; Leone, P; Malavasi, L; Monini, P; Palladino, C; Rezza, G; Sgadari, C; Toschi, E; Valdembri, D1
Burke, PA; DeNardo, GL; DeNardo, SJ; Kukis, DL; Miers, LA1
Alila, H; Bunn, PA; Chan, DC; Earle, K; Helfrich, B; Kelly, K; Pamukcu, R; Piazza, G; Thompson, W; Whitehead, CM; Zhao, TL1
Duray, PH; Figg, WD; Fisher, BA; Flynn, BM; Nguyen, DM; Schrump, DS; Terrill, RE; Weiser, TS; Zhai, S1
Larsson, LI; Lichtenberg, J1
Hu, J; Li, L; Ma, P; Zhang, S; Zhu, H1
Abdullah, SM; Gilani, SN; Gul, F; Ismail, M; Kaleem, WA; Khan, H; Khan, I; Khan, N; Nisar, M; Qayum, M; Shah, H; Shah, MR; Ullah, M1
Liang, ZS; Wang, LH; Yang, WX; Yu, SJ; Zhao, ZG1
Brandon, TA; Curry, SC; Gerkin, R; Graeme, KA; Miller, MB; Reagan, CG; Ruha, AM; Tanen, DA1
Du Nguyen, H; Horaguchi, Y; Kasanami, Y; Kawabata, A; Kitamura, S; Nishikawa, H; Okada, T; Sekiguchi, F; Toyooka, N; Tsubota, M; Yamaoka, S; Yoshida, S1

Reviews

23 review(s) available for paclitaxel and Disease Models, Animal

ArticleYear
Goshajinkigan attenuates paclitaxel-induced neuropathic pain via cortical astrocytes.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Hyperalgesia; Mice; Neuralgia; Paclitaxel; Somatosensory Cortex

2021
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus

2016
The Uniqueness of Albumin as a Carrier in Nanodrug Delivery.
    Molecular pharmaceutics, 2021, 05-03, Volume: 18, Issue:5

    Topics: Albumins; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Carriers; Half-Life; Humans; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Neoplasms; Paclitaxel; Serum Albumin, Human

2021
Preclinical and Clinical Evidence of Therapeutic Agents for Paclitaxel-Induced Peripheral Neuropathy.
    International journal of molecular sciences, 2021, Aug-13, Volume: 22, Issue:16

    Topics: Animals; Antineoplastic Agents, Phytogenic; Clinical Trials as Topic; Disease Models, Animal; Humans; Oxidative Stress; Paclitaxel; Peripheral Nervous System Diseases; Pre-Exposure Prophylaxis; Translational Research, Biomedical

2021
Modulating the endocannabinoid pathway as treatment for peripheral neuropathic pain: a selected review of preclinical studies.
    Annals of palliative medicine, 2017, Volume: 6, Issue:Suppl 2

    Topics: Animals; Antineoplastic Agents; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cisplatin; Disease Models, Animal; Endocannabinoids; Evaluation Studies as Topic; Hyperalgesia; Mice; Neuralgia; Paclitaxel; Rats; Signal Transduction

2017
Antimicrotubule Agent-Induced Zinc Neurotoxicity.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:7

    Topics: Animals; Cation Transport Proteins; Cell Death; Cognitive Dysfunction; Colchicine; Disease Models, Animal; Hippocampus; Humans; Mice; Microtubules; Neurogenesis; Neurons; Neurotoxicity Syndromes; Paclitaxel; Presynaptic Terminals; Tubulin Modulators; Vincristine

2018
Rodent models of chemotherapy-induced peripheral neuropathy.
    ILAR journal, 2014, Volume: 54, Issue:3

    Topics: Animals; Antineoplastic Agents; Axons; Boronic Acids; Bortezomib; Cisplatin; Disease Models, Animal; Mice; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases; Pyrazines; Rats; Vincristine

2014
Cell-penetrating, guanidinium-rich molecular transporters for overcoming efflux-mediated multidrug resistance.
    Molecular pharmaceutics, 2014, Aug-04, Volume: 11, Issue:8

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line, Tumor; Cell Membrane; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Guanidine; Humans; Mice; Oligopeptides; Ovarian Neoplasms; Paclitaxel; Peptides; Protein Transport; RNA Interference; Solubility; Water

2014
Syngeneic mouse model of epithelial ovarian cancer: effects of nanoparticulate paclitaxel, Nanotax.
    Advances in experimental medicine and biology, 2008, Volume: 622

    Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Delivery Systems; Female; Humans; Injections, Intralesional; Injections, Intraperitoneal; Mice; Nanoparticles; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Transplantation, Isogeneic

2008
Taxol: efficacy against oral squamous cell carcinoma.
    Mini reviews in medicinal chemistry, 2013, Volume: 13, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Survival; Clinical Trials as Topic; Disease Models, Animal; Drug Therapy, Combination; Humans; Mouth Neoplasms; Paclitaxel; Platinum Compounds; Survival Rate; Tongue Neoplasms

2013
Neuropathic pain associated with non-surgical treatment of breast cancer.
    Pain, 2005, Volume: 118, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease Models, Animal; Female; Humans; Neuralgia; Paclitaxel; Peripheral Nerves; Peripheral Nervous System Diseases; Radiation Injuries; Radiotherapy; Rats

2005
Update on drug-eluting stents for prevention of restenosis.
    Asian cardiovascular & thoracic annals, 2006, Volume: 14, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Coronary Restenosis; Disease Models, Animal; Drug Delivery Systems; Drug-Eluting Stents; Humans; Paclitaxel; Prosthesis Design; Sirolimus; Tubulin Modulators

2006
Drug-eluting stents studies in mice: do we need atherosclerosis to study restenosis?
    Vascular pharmacology, 2006, Volume: 44, Issue:5

    Topics: Animals; Atherosclerosis; Coronary Restenosis; Disease Models, Animal; Drug Delivery Systems; Drug Evaluation, Preclinical; Humans; Mice; Paclitaxel; Sirolimus; Stents

2006
Vascular responses to drug eluting stents: importance of delayed healing.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:7

    Topics: Aged; Angioplasty, Balloon, Coronary; Animals; Biopsy, Needle; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Disease Models, Animal; Endothelium, Vascular; Humans; Immunohistochemistry; Middle Aged; Paclitaxel; Prognosis; Prosthesis Design; Rabbits; Risk Factors; Sensitivity and Specificity; Sirolimus; Stents; Time Factors; Wound Healing

2007
The significance of preclinical evaluation of sirolimus-, paclitaxel-, and zotarolimus-eluting stents.
    The American journal of cardiology, 2007, Oct-22, Volume: 100, Issue:8B

    Topics: Animals; Antineoplastic Agents; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Humans; Iliac Artery; Paclitaxel; Rabbits; Sirolimus; Swine; Time Factors; Tunica Intima

2007
Preclinical investigations with epothilones in breast cancer models.
    Seminars in oncology, 2008, Volume: 35, Issue:2 Suppl 2

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Capecitabine; Cell Line, Tumor; Clinical Trials, Phase I as Topic; Deoxycytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Epothilones; Female; Fluorouracil; Humans; Mice; Mice, Nude; Microtubules; Paclitaxel; Tubulin Modulators

2008
Animal models in rheumatoid arthritis.
    Current opinion in rheumatology, 1995, Volume: 7, Issue:3

    Topics: Animals; Arthritis, Rheumatoid; Cell Adhesion; Cytokines; Disease Models, Animal; Humans; Major Histocompatibility Complex; Mice; Mice, SCID; Mice, Transgenic; Nitric Oxide; Paclitaxel; Synovitis; T-Lymphocytes

1995
[Combined effect of Paclitaxel and ionizing radiation. Experimental data of in-vitro and in-vivo models].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1996, Volume: 172 Suppl 1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Chemotherapy, Adjuvant; Disease Models, Animal; Humans; Neoplasms, Experimental; Paclitaxel; Radiation-Sensitizing Agents; Radiotherapy Dosage; Radiotherapy, Adjuvant; Tumor Cells, Cultured

1996
The taxanes: dosing and scheduling considerations.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:3 Suppl 2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease Models, Animal; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; In Vitro Techniques; Lung Neoplasms; Ovarian Neoplasms; Paclitaxel

1997
Docetaxel in breast cancer and a rationale for combination therapy.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:6 Suppl 6

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Models, Animal; Docetaxel; Drug Resistance, Neoplasm; Female; Humans; In Vitro Techniques; Mice; Paclitaxel; Taxoids

1997
Docetaxel in combination with fluorouracil for advanced solid tumors.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:8 Suppl 8

    Topics: Adult; Aged; Animals; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Disease Models, Animal; Docetaxel; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Leucovorin; Mice; Middle Aged; Mucous Membrane; Neoplasms; Neutropenia; Paclitaxel; Taxoids

1997
Neurotrophic factors and diabetic peripheral neuropathy.
    European neurology, 1999, Volume: 41 Suppl 1

    Topics: Animals; Diabetic Neuropathies; Disease Models, Animal; Humans; Nerve Compression Syndromes; Nerve Growth Factors; Paclitaxel; Peripheral Nervous System Diseases; Vinblastine

1999
Preclinical and clinical studies of docetaxel and exisulind in the treatment of human lung cancer.
    Seminars in oncology, 2002, Volume: 29, Issue:1 Suppl 4

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Disease Models, Animal; Docetaxel; Humans; Immunohistochemistry; Lung Neoplasms; Mice; Paclitaxel; Rats; Sulindac; Survival Analysis; Taxoids; Treatment Outcome; Tumor Cells, Cultured

2002

Trials

8 trial(s) available for paclitaxel and Disease Models, Animal

ArticleYear
Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer.
    Nature, 2023, Volume: 620, Issue:7973

    Topics: Animals; Biopsy; Carboplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Endometrial Neoplasms; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Humans; Mice; Netrin-1; Paclitaxel; RNA-Seq; Single-Cell Gene Expression Analysis; Tumor Microenvironment

2023
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus

2016
High-dose parenteral ascorbate enhanced chemosensitivity of ovarian cancer and reduced toxicity of chemotherapy.
    Science translational medicine, 2014, Feb-05, Volume: 6, Issue:222

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Carboplatin; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Infusions, Parenteral; Mice; Ovarian Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays

2014
Pharmacological Modulation of the Mitochondrial Electron Transport Chain in Paclitaxel-Induced Painful Peripheral Neuropathy.
    The journal of pain, 2015, Volume: 16, Issue:10

    Topics: Animals; Antimycin A; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Electron Transport; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Hyperalgesia; Male; Motor Activity; Paclitaxel; Pain; Pain Measurement; Peripheral Nervous System Diseases; Psychomotor Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Single-Blind Method; Time Factors

2015
SPARC Expression Did Not Predict Efficacy of nab-Paclitaxel plus Gemcitabine or Gemcitabine Alone for Metastatic Pancreatic Cancer in an Exploratory Analysis of the Phase III MPACT Trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Nov-01, Volume: 21, Issue:21

    Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Deoxycytidine; Disease Models, Animal; Female; Gemcitabine; Gene Expression; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Mice, Knockout; Neoplasm Metastasis; Osteonectin; Paclitaxel; Pancreatic Neoplasms; Stromal Cells; Treatment Outcome; Xenograft Model Antitumor Assays

2015
In vivo evaluation of intravesical paclitaxel and combined bcl-xL antisense oligodeoxynucleotide treatment for orthotopic urothelial carcinoma.
    Journal of cancer research and clinical oncology, 2009, Volume: 135, Issue:5

    Topics: Administration, Intravesical; Animals; Antineoplastic Agents, Phytogenic; bcl-X Protein; Carcinoma; Combined Modality Therapy; Disease Models, Animal; Humans; Kidney; Oligonucleotides, Antisense; Paclitaxel; Rats; Rats, Nude; Urinary Bladder Neoplasms; Urologic Neoplasms

2009
The anti-tumor agent sagopilone shows antiresorptive effects both in vitro and in vivo.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2011, Volume: 22, Issue:11

    Topics: Animals; Benzothiazoles; Bone Density; Bone Resorption; Disease Models, Animal; Epothilones; Female; Humans; Mice; Osteoclasts; Osteoporosis; Ovariectomy; Paclitaxel; Tubulin Modulators

2011
Dose-dense chemotherapy improves mechanisms of antitumor immune response.
    Cancer research, 2013, Jan-01, Volume: 73, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Immunoassay; Maximum Tolerated Dose; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasms, Experimental; Ovarian Neoplasms; Paclitaxel

2013

Other Studies

542 other study(ies) available for paclitaxel and Disease Models, Animal

ArticleYear
Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids.
    Bioorganic & medicinal chemistry letters, 2001, Mar-26, Volume: 11, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Chlorambucil; Disease Models, Animal; Female; Humans; Inhibitory Concentration 50; Mice; Neoplasm Transplantation; Ovarian Neoplasms; Paclitaxel; Sarcoma; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2001
Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests.
    Journal of natural products, 2002, Volume: 65, Issue:6

    Topics: Animals; Biological Factors; Colonic Neoplasms; Diosgenin; Disease Models, Animal; Diterpenes; Drug Screening Assays, Antitumor; Female; Heterocyclic Compounds, 3-Ring; HL-60 Cells; Humans; Inhibitory Concentration 50; KB Cells; Leukemia P388; Male; Melanoma; Mice; Molecular Structure; Naphthoquinones; Ovarian Neoplasms; Paclitaxel; Polymers; Prostatic Neoplasms; Triterpenes; Tumor Cells, Cultured

2002
Synthesis and antitumor activity evaluations of albumin-binding prodrugs of CC-1065 analog.
    Bioorganic & medicinal chemistry, 2008, Jul-01, Volume: 16, Issue:13

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Disease Models, Animal; Duocarmycins; Female; Humans; Indoles; Mice; Molecular Structure; Neoplasm Transplantation; Neoplasms; Prodrugs; Serum Albumin; Structure-Activity Relationship

2008
Antitumor Agents. 282. 2'-(R)-O-acetylglaucarubinone, a quassinoid from Odyendyea gabonensis as a potential anti-breast and anti-ovarian cancer agent.
    Journal of natural products, 2010, Sep-24, Volume: 73, Issue:9

    Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Humans; KB Cells; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Quassins; Stereoisomerism

2010
Novel second generation analogs of eribulin. Part III: Blood-brain barrier permeability and in vivo activity in a brain tumor model.
    Bioorganic & medicinal chemistry letters, 2011, Mar-15, Volume: 21, Issue:6

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Furans; Inhibitory Concentration 50; Ketones; Mice; Mice, Inbred BALB C

2011
Synthesis and biological evaluation of imidazolo[2,1-b]benzothiazole derivatives, as potential p53 inhibitors.
    Bioorganic & medicinal chemistry, 2011, Mar-01, Volume: 19, Issue:5

    Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Ovarian Neoplasms; Toluene; Transplantation, Heterologous; Tumor Suppressor Protein p53

2011
Cytotoxic dimeric epipolythiodiketopiperazines from the ascomycetous fungus Preussia typharum.
    Journal of natural products, 2014, Jun-27, Volume: 77, Issue:6

    Topics: Animals; Antineoplastic Agents; Ascomycota; ATP Binding Cassette Transporter, Subfamily B, Member 1; Disease Models, Animal; Drug Screening Assays, Antitumor; Humans; Melanoma; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Piperazines

2014
Triphenylphosphonium Cations of the Diterpenoid Isosteviol: Synthesis and Antimitotic Activity in a Sea Urchin Embryo Model.
    Journal of natural products, 2015, Jun-26, Volume: 78, Issue:6

    Topics: Animals; Antimitotic Agents; Antineoplastic Agents; Cations; Disease Models, Animal; Diterpenes; Diterpenes, Kaurane; Humans; Mediterranean Sea; Mitochondria; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organophosphorus Compounds; Sea Urchins; Structure-Activity Relationship

2015
Prodrugs of the cancer cell selective anti-cancer agent (Z)-2-(1H-indol-3-yl)-3-(isoquinolin-5-yl)acrylonitrile (A131) are orally efficacious in a mouse model of resistant colon cancer.
    Bioorganic & medicinal chemistry letters, 2019, 01-15, Volume: 29, Issue:2

    Topics: Acrylonitrile; Administration, Oral; Animals; Antineoplastic Agents; Colonic Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Indoles; Isoquinolines; Mice; Molecular Structure; Neoplasms, Experimental; Paclitaxel; Prodrugs; Solubility; Structure-Activity Relationship

2019
Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents.
    European journal of medicinal chemistry, 2020, Apr-01, Volume: 191

    Topics: Animals; Antineoplastic Agents; Carbazoles; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Rats; Solubility; Structure-Activity Relationship; Sulfonamides; Tumor Cells, Cultured; Water

2020
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Lead optimization generates selenium-containing miconazole CYP51 inhibitors with improved pharmacological profile for the treatment of fungal infections.
    European journal of medicinal chemistry, 2021, Apr-15, Volume: 216

    Topics: 14-alpha Demethylase Inhibitors; Animals; Antifungal Agents; Binding Sites; Biofilms; Candida; Candidiasis; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Design; Half-Life; Humans; Mice; Miconazole; Microbial Sensitivity Tests; Molecular Docking Simulation; Selenium; Sterol 14-Demethylase; Structure-Activity Relationship

2021
β2-adrenoreceptor agonist ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of mitochondrial biogenesis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 144

    Topics: Adrenergic beta-2 Receptor Agonists; Analgesics; Animals; Disease Models, Animal; DNA, Mitochondrial; Formoterol Fumarate; Male; Mitochondria; Neuralgia; Organelle Biogenesis; Paclitaxel; Pain Threshold; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Spinal Cord

2021
Microenvironment-Responsive Prodrug-Induced Pyroptosis Boosts Cancer Immunotherapy.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021, Volume: 8, Issue:24

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Drug Liberation; Female; Glutathione; Immunotherapy; Mice; Mice, Inbred BALB C; Paclitaxel; Photochemotherapy; Photosensitizing Agents; Prodrugs; Pyroptosis; Reactive Oxygen Species; Tumor Microenvironment

2021
The Cannabidiol Analog PECS-101 Prevents Chemotherapy-Induced Neuropathic Pain via PPARγ Receptors.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2022, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents; Cannabidiol; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Mice; Neuralgia; Paclitaxel; PPAR gamma

2022
Surface Modification of Nanoparticles Enhances Drug Delivery to the Brain and Improves Survival in a Glioblastoma Multiforme Murine Model.
    Bioconjugate chemistry, 2022, 11-16, Volume: 33, Issue:11

    Topics: Animals; Brain; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Glioblastoma; Humans; Lactic Acid; Mice; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution

2022
Nicotinamide Riboside Alleviates Corneal and Somatic Hypersensitivity Induced by Paclitaxel in Male Rats.
    Investigative ophthalmology & visual science, 2022, 01-03, Volume: 63, Issue:1

    Topics: Animals; Corneal Diseases; Disease Models, Animal; Hypersensitivity; Male; Niacinamide; Paclitaxel; Rats; Rats, Sprague-Dawley; Tears; Vitamin B Complex

2022
Feasibility of administering human pancreatic cancer chemotherapy in a spontaneous pancreatic cancer mouse model.
    BMC cancer, 2022, Feb-16, Volume: 22, Issue:1

    Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Disease Models, Animal; Feasibility Studies; Fluorouracil; Gemcitabine; Humans; Irinotecan; Leucovorin; Mice; Oxaliplatin; Paclitaxel; Pancreatic Neoplasms

2022
Dual targeting micelles loaded with paclitaxel and lapatinib for combinational therapy of brain metastases from breast cancer.
    Scientific reports, 2022, 02-16, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Blood-Brain Barrier; Brain; Brain Neoplasms; Breast Neoplasms; Disease Models, Animal; Drug Delivery Systems; Female; Humans; Injections, Intravenous; Lapatinib; Mice; Micelles; Paclitaxel; Peptides; Tumor Cells, Cultured

2022
Tumorigenic circulating tumor cells from xenograft mouse models of non-metastatic NSCLC patients reveal distinct single cell heterogeneity and drug responses.
    Molecular cancer, 2022, 03-12, Volume: 21, Issue:1

    Topics: Animals; Carboplatin; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Heterografts; Humans; Lung Neoplasms; Mice; Neoplastic Cells, Circulating; Paclitaxel

2022
Effect of CMB Carrying PTX and CRISPR/Cas9 on Endometrial Cancer Naked Mouse Model.
    Journal of healthcare engineering, 2022, Volume: 2022

    Topics: Animals; CRISPR-Cas Systems; Disease Models, Animal; Endometrial Neoplasms; Female; Glycogen Synthase Kinase 3; Humans; Mammals; Mice; Paclitaxel

2022
Use of paclitaxel carried in solid lipid nanoparticles to prevent peritoneal fibrosis in rats.
    PloS one, 2022, Volume: 17, Issue:5

    Topics: Animals; Disease Models, Animal; Female; Liposomes; Male; Nanoparticles; Paclitaxel; Peritoneal Fibrosis; Peritoneum; Rats; Rats, Wistar; Transforming Growth Factor beta

2022
An injectable thermosensitive hydrogel/nanomicelles composite for local chemo-immunotherapy in mouse model of melanoma.
    Journal of biomaterials applications, 2022, Volume: 37, Issue:3

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hydrogels; Immunotherapy; Melanoma; Mice; Micelles; Paclitaxel; Poloxamer

2022
Systemic, Intrathecal, and Intracerebroventricular Antihyperalgesic Effects of the Calcium Channel Blocker CTK 01512-2 Toxin in Persistent Pain Models.
    Molecular neurobiology, 2022, Volume: 59, Issue:7

    Topics: Animals; Calcium Channel Blockers; Chronic Pain; Disease Models, Animal; Humans; Hyperalgesia; omega-Conotoxins; Paclitaxel; Spider Venoms

2022
Rottlerin promotes anti-metastatic events by ameliorating pharmacological parameters of paclitaxel: An in-vivo investigation in the orthotopic mouse model of breast cancer.
    Chemico-biological interactions, 2022, Oct-01, Volume: 366

    Topics: Acetophenones; Animals; Apoptosis Regulatory Proteins; Benzopyrans; Cadherins; Cell Line, Tumor; Disease Models, Animal; Epithelial-Mesenchymal Transition; Humans; Mice; Paclitaxel; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Triple Negative Breast Neoplasms; Vimentin

2022
Effect of acoustic cluster therapy (ACT®) combined with chemotherapy in a patient-derived xenograft mouse model of pancreatic cancer.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 352

    Topics: Acoustics; Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Disease Models, Animal; Heterografts; Humans; Mice; Paclitaxel; Pancreatic Neoplasms; Xenograft Model Antitumor Assays

2022
Design, synthesis, and biological evaluation of novel HSP27 inhibitors to sensitize lung cancer cells to clinically available anticancer agents.
    Bioorganic chemistry, 2023, Volume: 130

    Topics: Animals; Antineoplastic Agents; Cisplatin; Disease Models, Animal; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Lung Neoplasms; Mice; Paclitaxel

2023
Chondroitin Sulfate Targeting Nanodrug Achieves Near-Infrared Fluorescence-Guided Chemotherapy Against Triple-Negative Breast Primary and Lung Metastatic Cancer.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Animals; Chondroitin Sulfates; Disease Models, Animal; Humans; Lung; Lung Neoplasms; Mice; Nanospheres; Paclitaxel; Triple Negative Breast Neoplasms

2022
Hsa_circ_0092887 targeting miR-490-5p/UBE2T promotes paclitaxel resistance in non-small cell lung cancer.
    Journal of clinical laboratory analysis, 2023, Volume: 37, Issue:1

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Humans; Lung Neoplasms; Mice; MicroRNAs; Paclitaxel; Ubiquitin-Conjugating Enzymes

2023
TRIM6 Reduces Ferroptosis and Chemosensitivity by Targeting SLC1A5 in Lung Cancer.
    Oxidative medicine and cellular longevity, 2023, Volume: 2023

    Topics: Amino Acid Transport System ASC; Animals; Cell Death; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Ferroptosis; Humans; Lung Neoplasms; Mice; Minor Histocompatibility Antigens; Paclitaxel; Tripartite Motif Proteins; Ubiquitin-Protein Ligases

2023
Paclitaxel Has a Reduced Toxicity Profile in Healthy Rats After Polymeric Micellar Nanoparticle Delivery.
    International journal of nanomedicine, 2023, Volume: 18

    Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Humans; Lung Neoplasms; Male; Mammals; Micelles; Nanoparticles; Paclitaxel; Peripheral Nervous System Diseases; Polymers; Rats; Rats, Sprague-Dawley

2023
Zhuidu Formula suppresses the migratory and invasive properties of triple-negative breast cancer cells via dual signaling pathways of RhoA/ROCK and CDC42/MRCK.
    Journal of ethnopharmacology, 2023, Oct-28, Volume: 315

    Topics: Actins; Animals; Cell Adhesion; Cell Growth Processes; Cell Movement; Cytoskeleton; Disease Models, Animal; Drug Synergism; Ethnopharmacology; Female; Humans; Matrix Metalloproteinases; MDA-MB-231 Cells; Medicine, Chinese Traditional; Mice; Myotonin-Protein Kinase; Neoplasm Invasiveness; Neoplasm Metastasis; Paclitaxel; rho-Associated Kinases; Signal Transduction; Triple Negative Breast Neoplasms

2023
Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain.
    Aging cell, 2023, Volume: 22, Issue:7

    Topics: Animals; Chemotherapy-Related Cognitive Impairment; Cognitive Dysfunction; Disease Models, Animal; Endothelial Cells; Mice; Paclitaxel; Senotherapeutics

2023
Blocking the functional domain of TIP1 by antibodies sensitizes cancer to radiation therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 166

    Topics: Animals; Antibodies; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Glioblastoma; Humans; Lung Neoplasms; Mice; Paclitaxel

2023
Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors.
    ACS nano, 2019, 10-22, Volume: 13, Issue:10

    Topics: Adenocarcinoma; Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Membrane Permeability; Collagen; Collagenases; Disease Models, Animal; Extracellular Matrix; Fibrosis; Humans; Liposomes; Mice; Nanoparticles; Paclitaxel; Pancreas; Tumor Microenvironment

2019
Development of drug-coated balloon for the treatment of multiple peripheral artery segments.
    Journal of vascular surgery, 2020, Volume: 71, Issue:5

    Topics: Angioplasty, Balloon; Animals; Cardiovascular Agents; Coated Materials, Biocompatible; Disease Models, Animal; Paclitaxel; Particulate Matter; Peripheral Arterial Disease; Swine; Vascular Patency

2020
Enhancing intratumoral biodistribution and antitumor activity of nab-paclitaxel through combination with a vascular disrupting agent, combretastatin A-4-phosphate.
    Cancer chemotherapy and pharmacology, 2019, Volume: 84, Issue:6

    Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Female; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Paclitaxel; Rats; Stilbenes; Tissue Distribution

2019
A Novel Paclitaxel Conjugate with Higher Efficiency and Lower Toxicity: A New Drug Candidate for Cancer Treatment.
    International journal of molecular sciences, 2019, Oct-08, Volume: 20, Issue:19

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Paclitaxel; Thioctic Acid; Xenograft Model Antitumor Assays

2019
The Involvement of the RhoA/ROCK Signaling Pathway in Hypersensitivity Reactions Induced by Paclitaxel Injection.
    International journal of molecular sciences, 2019, Oct-09, Volume: 20, Issue:20

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biopsy; Complement Activation; Complement System Proteins; Disease Models, Animal; Drug Hypersensitivity; Female; Histamine Release; Male; Mice; Paclitaxel; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

2019
A Paclitaxel-Based Mucoadhesive Nanogel with Multivalent Interactions for Cervical Cancer Therapy.
    Small (Weinheim an der Bergstrasse, Germany), 2019, Volume: 15, Issue:47

    Topics: Acrylic Resins; Adhesiveness; Animals; beta-Cyclodextrins; Cell Death; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Disease Models, Animal; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endocytosis; Female; Humans; Mice, Inbred BALB C; Mice, Nude; Mucins; Mucus; Nanogels; Paclitaxel; Solubility; Uterine Cervical Neoplasms

2019
Evaluation of intestinal permeation enhancement with carboxymethyl chitosan-rhein polymeric micelles for oral delivery of paclitaxel.
    International journal of pharmaceutics, 2020, Jan-05, Volume: 573

    Topics: Administration, Oral; Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Humans; Intestinal Mucosa; Male; Mice; Micelles; Neoplasms; Paclitaxel; Permeability; Rats; Tissue Distribution; Verapamil

2020
The role of propolis against paclitaxel-induced oligospermia, sperm abnormality, oxidative stress and DNA damage in testes of male rats.
    Andrologia, 2020, Volume: 52, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Apitherapy; Disease Models, Animal; DNA Damage; Humans; Male; Neoplasms; Oligospermia; Oxidative Stress; Paclitaxel; Propolis; Rats; Semen; Sperm Motility; Testis

2020
Local and Systemic Antitumor Effects of Photo-activatable Paclitaxel Prodrug on Rat Breast Tumor Models.
    Photochemistry and photobiology, 2020, Volume: 96, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease Models, Animal; Female; Humans; Paclitaxel; Photochemotherapy; Prodrugs; Rats; Rats, Inbred F344

2020
A Novel Epigenetic Drug-Eluting Balloon Angioplasty Device: Evaluation in a Large Animal Model of Neointimal Hyperplasia.
    Cardiovascular drugs and therapy, 2019, Volume: 33, Issue:6

    Topics: Angioplasty, Balloon; Animals; Carotid Artery Diseases; Carotid Artery, Common; Cell Proliferation; Cells, Cultured; Coated Materials, Biocompatible; Disease Models, Animal; Epigenesis, Genetic; Equipment Design; Female; Histone Deacetylase Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Inflammation Mediators; Neointima; Paclitaxel; Sheep, Domestic; Time Factors; Vascular Access Devices

2019
Dominant Role of the Gut Microbiota in Chemotherapy Induced Neuropathic Pain.
    Scientific reports, 2019, 12-30, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Biodiversity; Brain; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Male; Mice; Microglia; Neuralgia; Paclitaxel; Spinal Cord

2019
Therapy-Induced Senescence Drives Bone Loss.
    Cancer research, 2020, 03-01, Volume: 80, Issue:5

    Topics: Animals; Antineoplastic Agents; Cellular Senescence; Disease Models, Animal; Doxorubicin; Femur; Humans; Injections, Intraperitoneal; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Mice, Transgenic; Neoplasms; Osteoporosis; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Protein Serine-Threonine Kinases; X-Ray Microtomography

2020
Chemopreventive efficacy of stampidine in a murine breast cancer model.
    Expert opinion on therapeutic targets, 2020, Volume: 24, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Breast Neoplasms; Dideoxynucleotides; Disease Models, Animal; Disease-Free Survival; Female; Mice; Mice, Inbred BALB C; Paclitaxel; Stavudine; Survival Rate; Thymidine Monophosphate; Time Factors

2020
Paclitaxel-loaded expansile nanoparticles improve survival following cytoreductive surgery in pleural mesothelioma xenografts.
    The Journal of thoracic and cardiovascular surgery, 2020, Volume: 160, Issue:3

    Topics: Animals; Cell Line, Tumor; Combined Modality Therapy; Cytoreduction Surgical Procedures; Disease Models, Animal; Disease Progression; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mice; Nanoparticles; Paclitaxel; Pleural Neoplasms; Pneumonectomy; Tumor Burden; Xenograft Model Antitumor Assays

2020
Low-dose paclitaxel via hyaluronan-functionalized bovine serum albumin nanoparticulate assembly for metastatic melanoma treatment.
    Journal of materials chemistry. B, 2020, 03-11, Volume: 8, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cations; Cell Movement; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Hyaluronic Acid; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Particle Size; Serum Albumin, Bovine; Surface Properties; Tumor Cells, Cultured

2020
Upregulation of TRPC6 Mediated by PAX6 Hypomethylation Is Involved in the Mechanical Allodynia Induced by Chemotherapeutics in Dorsal Root Ganglion.
    The international journal of neuropsychopharmacology, 2020, 04-23, Volume: 23, Issue:4

    Topics: Animals; Antineoplastic Agents; Bortezomib; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Ganglia, Spinal; Gene Expression; Hyperalgesia; Male; Neuralgia; Oxaliplatin; Paclitaxel; PAX6 Transcription Factor; Rats; Rats, Sprague-Dawley; TRPC Cation Channels; Up-Regulation

2020
Liuwei Dihuang pill suppresses metastasis by regulating the wnt pathway and disrupting -catenin/T cell factor interactions in a murine model of triple-negative breast cancer.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2019, Volume: 39, Issue:6

    Topics: Animals; beta Catenin; Blotting, Western; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fluorescent Antibody Technique; Immunoprecipitation; Mice; Paclitaxel; TCF Transcription Factors; Triple Negative Breast Neoplasms; Wnt Signaling Pathway

2019
Neurofilament light chain: a specific serum biomarker of axonal damage severity in rat models of Chemotherapy-Induced Peripheral Neurotoxicity.
    Archives of toxicology, 2020, Volume: 94, Issue:7

    Topics: Animals; Antineoplastic Agents; Axons; Biomarkers; Cisplatin; Disease Models, Animal; Female; Neurofilament Proteins; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nerves; Peripheral Nervous System Diseases; Rats, Wistar; Severity of Illness Index; Up-Regulation

2020
Knockdown of A-kinase anchor protein 4 inhibits proliferation of triple-negative breast cancer cells
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2020, Volume: 42, Issue:4

    Topics: A Kinase Anchor Proteins; Animals; Apoptosis; Biomarkers; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Gene Knockdown Techniques; Gene Silencing; Humans; Immunophenotyping; Mice; Oxidative Stress; Paclitaxel; Reactive Oxygen Species; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2020
Paclitaxel Induces Immunogenic Cell Death in Ovarian Cancer via TLR4/IKK2/SNARE-Dependent Exocytosis.
    Cancer immunology research, 2020, Volume: 8, Issue:8

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Cancer Vaccines; Cell Line, Tumor; Disease Models, Animal; Exocytosis; Female; Humans; I-kappa B Kinase; Immunogenic Cell Death; Mice; Mice, Inbred C57BL; Middle Aged; Ovarian Neoplasms; Paclitaxel; Signal Transduction; SNARE Proteins; Toll-Like Receptor 4

2020
Eribulin Regresses a Cisplatinum-resistant Rare-type Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft Mouse Model.
    Anticancer research, 2020, Volume: 40, Issue:5

    Topics: Animals; Biomarkers, Tumor; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Furans; Humans; Ketones; Mice; Paclitaxel; Treatment Outcome; Triple Negative Breast Neoplasms; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020
Local Sympathectomy Promotes Anti-inflammatory Responses and Relief of Paclitaxel-induced Mechanical and Cold Allodynia in Mice.
    Anesthesiology, 2020, Volume: 132, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cold Temperature; Disease Models, Animal; Female; Hyperalgesia; Inflammation; Male; Mice; Paclitaxel; Sympathectomy

2020
Losartan attenuates neuroinflammation and neuropathic pain in paclitaxel-induced peripheral neuropathy.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:14

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ganglia, Spinal; Losartan; Macrophages; Male; Neuralgia; Paclitaxel; Pain Management; Rats

2020
A Chemotherapy-Induced Peripheral Neuropathy Model in Drosophila melanogaster.
    Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2143

    Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents; Axons; Dendrites; Disease Models, Animal; Dissection; Drosophila melanogaster; Female; Genotype; Larva; Male; Microscopy, Fluorescence; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases

2020
PPARγ activation mitigates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of Nrf2/HO-1 signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Analgesics; Animals; Disease Models, Animal; Heme Oxygenase (Decyclizing); Hyperalgesia; Male; Neuralgia; NF-E2-Related Factor 2; Paclitaxel; Pain Perception; Pain Threshold; PPAR gamma; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Spinal Cord; Up-Regulation

2020
Paclitaxel Induces Upregulation of Transient Receptor Potential Vanilloid 1 Expression in the Rat Spinal Cord.
    International journal of molecular sciences, 2020, Jun-18, Volume: 21, Issue:12

    Topics: Acrylamides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Paclitaxel; Rats; RNA, Small Interfering; Spinal Cord; TRPV Cation Channels; Up-Regulation

2020
Monosialoganglioside GM1 reduces toxicity of Ptx and increase anti-metastasic effect in a murine mammary cancer model.
    Scientific reports, 2020, 06-23, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Gangliosides; Male; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Polyethylene Glycols

2020
JTC-801 alleviates mechanical allodynia in paclitaxel-induced neuropathic pain through the PI3K/Akt pathway.
    European journal of pharmacology, 2020, Sep-15, Volume: 883

    Topics: Aminoquinolines; Analgesics; Animals; Behavior, Animal; Benzamides; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Inflammation Mediators; Interleukin-1beta; Male; Narcotic Antagonists; Neuralgia; Nociceptin Receptor; Paclitaxel; Pain Threshold; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Receptors, Opioid; Signal Transduction; Tumor Necrosis Factor-alpha

2020
Peripheral deficiency and antiallodynic effects of 2-arachidonoyl glycerol in a mouse model of paclitaxel-induced neuropathic pain.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Analgesics; Animals; Arachidonic Acids; Benzodioxoles; Cannabinoid Receptor Agonists; Disease Models, Animal; Endocannabinoids; Enzyme Inhibitors; Female; Glycerides; Hyperalgesia; Mice, Inbred BALB C; Monoacylglycerol Lipases; Neuralgia; Paclitaxel; Piperidines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Skin

2020
Novel monoclonal antibody against integrin α3 shows therapeutic potential for ovarian cancer.
    Cancer science, 2020, Volume: 111, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Apoptosis; Carboplatin; Carcinoma; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Female; HCT116 Cells; Human Umbilical Vein Endothelial Cells; Humans; Integrin alpha3; Mice; Mice, Inbred BALB C; Neoplasm Recurrence, Local; Ovarian Neoplasms; Paclitaxel; Prognosis; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2020
LINC00160 mediated paclitaxel-And doxorubicin-resistance in breast cancer cells by regulating TFF3 via transcription factor C/EBPβ.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:15

    Topics: Adult; Animals; Biomarkers, Tumor; Breast Neoplasms; CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mice; Middle Aged; Paclitaxel; Prognosis; RNA Interference; RNA, Long Noncoding; Transcription Factors; Trefoil Factor-3; Xenograft Model Antitumor Assays

2020
Nanomicelle protects the immune activation effects of Paclitaxel and sensitizes tumors to anti-PD-1 Immunotherapy.
    Theranostics, 2020, Volume: 10, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Endoplasmic Reticulum Stress; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Immunogenic Cell Death; Immunotherapy; Mice; Micelles; Nanoparticles; Neoplasms; Paclitaxel; Programmed Cell Death 1 Receptor; Tumor Microenvironment

2020
Circadian regulation of chemotherapy-induced peripheral neuropathic pain and the underlying transcriptomic landscape.
    Scientific reports, 2020, 08-14, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; ARNTL Transcription Factors; Circadian Rhythm; Disease Models, Animal; Ganglia, Spinal; Gene Expression; In Vitro Techniques; Mice; Neuralgia; Paclitaxel; Period Circadian Proteins; Peripheral Nerve Injuries; Rats; Spinal Cord Dorsal Horn

2020
Safety, pharmacokinetics and tissue penetration of PIPAC paclitaxel in a swine model.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2021, Volume: 47, Issue:5

    Topics: Animals; Biopsy; Disease Models, Animal; Female; Hyperthermic Intraperitoneal Chemotherapy; Paclitaxel; Peritoneal Neoplasms; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine

2021
Iridoids isolated from Viticis Fructus inhibit paclitaxel-induced mechanical allodynia in mice.
    Journal of natural medicines, 2021, Volume: 75, Issue:1

    Topics: Animals; Disease Models, Animal; Drug Interactions; Hyperalgesia; Iridoids; Male; Mice; Mice, Inbred C57BL; Paclitaxel; Plant Extracts; Vitex

2021
Design, manufacture and initial tests of a drug-eluting coronary stent.
    Gaceta medica de Mexico, 2020, Volume: 156, Issue:4

    Topics: Animals; Disease Models, Animal; Drug-Eluting Stents; Female; Follow-Up Studies; Male; Microscopy; Paclitaxel; Prosthesis Design; Rabbits; Sirolimus; Spectrophotometry, Infrared; Swine

2020
Umbelliprenin relieves paclitaxel-induced neuropathy.
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:12

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Interleukin-6; Lipid Peroxidation; Male; Mice; Oxidative Stress; Paclitaxel; Pain Threshold; Sciatic Nerve; Sciatic Neuropathy; Umbelliferones

2020
PINK1 alleviates thermal hypersensitivity in a paclitaxel-induced Drosophila model of peripheral neuropathy.
    PloS one, 2020, Volume: 15, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drosophila; Drosophila Proteins; Gene Expression; Gene Knockdown Techniques; Hyperalgesia; Hyperesthesia; Paclitaxel; Peripheral Nervous System Diseases; Protein Serine-Threonine Kinases; Sensory Receptor Cells

2020
Transient impact of paclitaxel on mouse fertility and protective effect of gonadotropin‑releasing hormone agonist.
    Oncology reports, 2020, Volume: 44, Issue:5

    Topics: Animals; Disease Models, Animal; Female; Fertility; Fertility Preservation; Gonadotropin-Releasing Hormone; Humans; Mice; Mice, Inbred ICR; Neoplasms; Ovarian Follicle; Ovulation Induction; Paclitaxel; Primary Ovarian Insufficiency

2020
CREB Participates in Paclitaxel-Induced Neuropathic Pain Genesis Through Transcriptional Activation of Dnmt3a in Primary Sensory Neurons.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:1

    Topics: Animals; Blotting, Western; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; DNA Methyltransferase 3A; Fluorescent Antibody Technique; Ganglia, Spinal; Male; Mice; Neuralgia; Paclitaxel; Sensory Receptor Cells; Transcriptional Activation; Up-Regulation

2021
Local Targeting of Lung-Tumor-Associated Macrophages with Pulmonary Delivery of a CSF-1R Inhibitor for the Treatment of Breast Cancer Lung Metastases.
    Molecular pharmaceutics, 2020, 12-07, Volume: 17, Issue:12

    Topics: Administration, Inhalation; Administration, Intravenous; Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Lung Neoplasms; Mice; Paclitaxel; Phosphorylation; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Tumor Microenvironment; Tumor-Associated Macrophages

2020
Deficit in voluntary wheel running in chronic inflammatory and neuropathic pain models in mice: Impact of sex and genotype.
    Behavioural brain research, 2021, 02-05, Volume: 399

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Phytogenic; Chronic Pain; Disease Models, Animal; Female; Freund's Adjuvant; Genotype; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Neuralgia; Nociceptive Pain; Paclitaxel; Peripheral Nerve Injuries; Running; Sex Factors

2021
Involvement of TACAN, a Mechanotransducing Ion Channel, in Inflammatory But Not Neuropathic Hyperalgesia in the Rat.
    The journal of pain, 2021, Volume: 22, Issue:5

    Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Inflammation; Ion Channels; Male; Mechanotransduction, Cellular; Neuralgia; Oxaliplatin; Paclitaxel; Pain Threshold; Rats; Rats, Sprague-Dawley

2021
Depletion and Maturation of Myeloid-Derived Suppressor Cells in Murine Cancer Models.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2236

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Differentiation; Disease Models, Animal; Mice, Inbred C57BL; Mice, Transgenic; Myeloid-Derived Suppressor Cells; Neoplasms; Paclitaxel; Tretinoin

2021
Human Intravenous Immunoglobulin Alleviates Neuropathic Symptoms in a Rat Model of Paclitaxel-Induced Peripheral Neurotoxicity.
    International journal of molecular sciences, 2021, Jan-21, Volume: 22, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Axons; Biomarkers; Disease Models, Animal; Disease Susceptibility; Humans; Hyperalgesia; Immunoglobulins, Intravenous; Macrophages; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nervous System Diseases; Rats; Treatment Outcome

2021
Analgesic Effects of Sokeikakketsuto on Chemotherapy-Induced Mechanical Allodynia and Cold Hyperalgesia in Rats.
    Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:2

    Topics: Analgesics; Animals; Antineoplastic Agents; Bortezomib; Cold Temperature; Disease Models, Animal; Drugs, Chinese Herbal; Duloxetine Hydrochloride; Humans; Hyperalgesia; Male; Medicine, Kampo; Oxaliplatin; Paclitaxel; Pain Measurement; Rats; Rats, Sprague-Dawley

2021
Pronociceptive Roles of Schwann Cell-Derived Galectin-3 in Taxane-Induced Peripheral Neuropathy.
    Cancer research, 2021, 04-15, Volume: 81, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Proteins; Cell Movement; Chemotaxis; Clodronic Acid; Disease Models, Animal; Docetaxel; Female; Galectins; Humans; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Paclitaxel; Pain Perception; Peripheral Nervous System Diseases; Prospective Studies; Rats; Schwann Cells; Sciatic Nerve; Up-Regulation

2021
Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome.
    Cardiovascular research, 2022, 01-29, Volume: 118, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cytoskeleton; Disease Models, Animal; Excitation Contraction Coupling; Female; Genetic Predisposition to Disease; Heart Conduction System; Heart Rate; Lamin Type A; Male; Mice, Mutant Strains; Mutation; Myocytes, Cardiac; Paclitaxel; Progeria; Refractory Period, Electrophysiological; Swine; Swine, Miniature; Tubulin

2022
Lyophilization Serves as an Effective Strategy for Drug Development of the α9α10 Nicotinic Acetylcholine Receptor Antagonist α-Conotoxin GeXIVA[1,2].
    Marine drugs, 2021, Feb-25, Volume: 19, Issue:3

    Topics: Acute Pain; Analgesics; Animals; Conotoxins; Disease Models, Animal; Drug Development; Freeze Drying; Male; Neuralgia; Nicotinic Antagonists; Paclitaxel; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic

2021
Chemotherapeutic Agent-Induced Vulvodynia, an Experimental Model.
    AAPS PharmSciTech, 2021, Mar-08, Volume: 22, Issue:3

    Topics: Analgesics; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Female; Gabapentin; Neuralgia; Paclitaxel; Pain Measurement; Rats; Rats, Sprague-Dawley; Vulvodynia

2021
Protective effects of paclitaxel on thioacetamide-induced liver fibrosis in a rat model.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:5

    Topics: Animals; Disease Models, Animal; Liver Cirrhosis; Male; Paclitaxel; Rats; Rats, Sprague-Dawley; Thioacetamide

2021
Oral recombinant methioninase combined with paclitaxel arrests recalcitrant ovarian clear cell carcinoma growth in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.
    Cancer chemotherapy and pharmacology, 2021, Volume: 88, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carbon-Sulfur Lyases; Carcinoma; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Heterografts; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Recombinant Proteins; Sarcoma, Clear Cell; Tumor Burden; Xenograft Model Antitumor Assays

2021
Decursin Alleviates Mechanical Allodynia in a Paclitaxel-Induced Neuropathic Pain Mouse Model.
    Cells, 2021, 03-04, Volume: 10, Issue:3

    Topics: Animals; Benzopyrans; Butyrates; Disease Models, Animal; Enzyme Activators; Humans; Hyperalgesia; Mice; Neuralgia; Paclitaxel

2021
Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy.
    Nature communications, 2021, 04-22, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Carriers; Female; Fluorescent Dyes; Humans; Intravital Microscopy; Mice; Molecular Imaging; Molecular Probes; Nanoparticles; Neoplasms; Optical Imaging; Paclitaxel; Patient Selection; Reproducibility of Results; Theranostic Nanomedicine; Tissue Distribution; Tumor Microenvironment

2021
Phenylboronic acid modified nanoparticles simultaneously target pancreatic cancer and its metastasis and alleviate immunosuppression.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 165

    Topics: Animals; Boronic Acids; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Human Umbilical Vein Endothelial Cells; Humans; Male; Membrane Glycoproteins; Mice; Myeloid-Derived Suppressor Cells; Nanoparticles; Paclitaxel; Pancreatic Neoplasms; Tumor Escape; Tumor Microenvironment

2021
Systemic metastasis-targeted nanotherapeutic reinforces tumor surgical resection and chemotherapy.
    Nature communications, 2021, 05-27, Volume: 12, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chemotherapy, Adjuvant; Disease Models, Animal; Drug Carriers; Epithelial-Mesenchymal Transition; Female; Heparin, Low-Molecular-Weight; Human Umbilical Vein Endothelial Cells; Humans; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Nanoparticles; Neoplasm Metastasis; Neoplastic Cells, Circulating; Paclitaxel; Proof of Concept Study; Rats; Stilbenes; Theranostic Nanomedicine

2021
Pharmacological rescue of cognitive function in a mouse model of chemobrain.
    Molecular neurodegeneration, 2021, 06-26, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Chemotherapy-Related Cognitive Impairment; Cognition; Disease Models, Animal; Female; Inositol 1,4,5-Trisphosphate Receptors; Lithium Chloride; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Paclitaxel

2021
Vimentin Promotes the Aggressiveness of Triple Negative Breast Cancer Cells Surviving Chemotherapeutic Treatment.
    Cells, 2021, 06-15, Volume: 10, Issue:6

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cyclophosphamide; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Therapy; Epirubicin; Epithelial-Mesenchymal Transition; Female; Humans; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Paclitaxel; Triple Negative Breast Neoplasms; Vimentin; Zebrafish

2021
Comparative colloidal stability, antitumor efficacy, and immunosuppressive effect of commercial paclitaxel nanoformulations.
    Journal of nanobiotechnology, 2021, Jul-05, Volume: 19, Issue:1

    Topics: Albumins; Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Emulsions; Female; Immunosuppressive Agents; Immunotherapy; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Nanomedicine; Nanoparticles; Paclitaxel; Triple Negative Breast Neoplasms

2021
Intranasal Paclitaxel Alters Alzheimer's Disease Phenotypic Features in 3xTg-AD Mice.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 83, Issue:1

    Topics: Administration, Intranasal; Alzheimer Disease; Animals; Antineoplastic Agents, Phytogenic; Axonal Transport; Blood-Brain Barrier; Brain; Disease Models, Animal; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Transgenic; Morris Water Maze Test; Neurons; Paclitaxel

2021
Akt targeting as a strategy to boost chemotherapy efficacy in non-small cell lung cancer through metabolism suppression.
    Scientific reports, 2017, 03-23, Volume: 7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Culture Techniques; Cell Cycle Checkpoints; Cell Line, Tumor; Disease Models, Animal; Energy Metabolism; Glycolysis; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Mice; Mitochondria; Paclitaxel; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays

2017
Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats.
    Pain, 2017, Volume: 158, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Eosinophils; Escape Reaction; Female; Hyperalgesia; Leukocyte Count; Locomotion; NAD; Neutrophils; Niacinamide; Nociception; Paclitaxel; Pain Measurement; Peripheral Nervous System Diseases; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Time Factors

2017
Influence of Drugs Carried in Lipid Nanoparticles in Coronary Disease of Rabbit Transplanted Heart.
    The Annals of thoracic surgery, 2017, Volume: 104, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Coronary Artery Disease; Cytokines; Disease Models, Animal; Drug Carriers; Gene Expression Regulation; Graft Rejection; Graft Survival; Heart Transplantation; Immunohistochemistry; Immunosuppressive Agents; Injections, Intravenous; Methotrexate; Myocardium; Nanoparticles; Paclitaxel; Rabbits; Real-Time Polymerase Chain Reaction; RNA

2017
Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy.
    Scientific reports, 2017, 03-28, Volume: 7

    Topics: Alopecia; Animals; Antineoplastic Agents, Phytogenic; Calcium; Cell Line, Tumor; Disease Models, Animal; Ganglia, Spinal; Humans; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Minoxidil; Neoplasms; Neurites; Neuroprotective Agents; Paclitaxel; Peripheral Nervous System Diseases; Sciatic Nerve

2017
Targeting Smoothened Sensitizes Gastric Cancer to Chemotherapy in Experimental Models.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Mar-28, Volume: 23

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; Male; Mice, Inbred C57BL; Paclitaxel; Smoothened Receptor; Stomach Neoplasms

2017
Antibody-targeted paclitaxel loaded nanoparticles for the treatment of CD20
    Scientific reports, 2017, 04-05, Volume: 7

    Topics: Animals; Antigens, CD20; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Humans; Lymphoma, B-Cell; Mice; Molecular Targeted Therapy; Nanoparticles; Paclitaxel; Rituximab; Treatment Outcome

2017
Oral cancer cells sustainedly infected with Porphyromonas gingivalis exhibit resistance to Taxol and have higher metastatic potential.
    Oncotarget, 2017, Jul-18, Volume: 8, Issue:29

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bacteroidaceae Infections; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression; Humans; Male; Mice; Mouth Neoplasms; Neoplasm Metastasis; Paclitaxel; Porphyromonas gingivalis; Receptor, Notch1; Xenograft Model Antitumor Assays

2017
Microtubule-Targeting Agents Eribulin and Paclitaxel Differentially Affect Neuronal Cell Bodies in Chemotherapy-Induced Peripheral Neuropathy.
    Neurotoxicity research, 2017, Volume: 32, Issue:1

    Topics: Activating Transcription Factor 3; Animals; Antineoplastic Agents; Cell Body; Disease Models, Animal; Female; Furans; Ganglia, Spinal; Ketones; Mice; Mice, Inbred BALB C; Microtubules; Paclitaxel; Sciatic Neuropathy; Sensory Receptor Cells; Tubulin

2017
Paclitaxel synergizes with exposure time adjusted CD22-targeting immunotoxins against B-cell malignancies.
    Oncotarget, 2017, May-09, Volume: 8, Issue:19

    Topics: Animals; Antineoplastic Agents; Bacterial Toxins; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Exotoxins; Humans; Immunotoxins; Mice; Paclitaxel; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Sialic Acid Binding Ig-like Lectin 2; Treatment Outcome; Xenograft Model Antitumor Assays

2017
Kanglaite sensitizes colorectal cancer cells to Taxol via NF-κΒ inhibition and connexin 43 upregulation.
    Scientific reports, 2017, 04-28, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colorectal Neoplasms; Connexin 43; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Mice, Inbred BALB C; NF-kappa B; Paclitaxel; Treatment Outcome; Up-Regulation

2017
Taxol alleviates collagen-induced arthritis in mice by inhibiting the formation of microvessels.
    Clinical rheumatology, 2019, Volume: 38, Issue:1

    Topics: Animals; Arthritis, Experimental; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microvessels; Neovascularization, Pathologic; Paclitaxel; Synovial Membrane; Vascular Endothelial Growth Factor A

2019
Deletion of Sarm1 gene is neuroprotective in two models of peripheral neuropathy.
    Journal of the peripheral nervous system : JPNS, 2017, Volume: 22, Issue:3

    Topics: Action Potentials; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Armadillo Domain Proteins; Cytoskeletal Proteins; Diet, High-Fat; Disease Models, Animal; Hyperalgesia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Conduction; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Reaction Time; Sural Nerve

2017
Impact of Fluoropolymer-Based Paclitaxel Delivery on Neointimal Proliferation and Vascular Healing: A Comparative Peripheral Drug-Eluting Stent Study in the Familial Hypercholesterolemic Swine Model of Femoral Restenosis.
    Circulation. Cardiovascular interventions, 2017, Volume: 10, Issue:5

    Topics: Angiography; Animals; Cardiovascular Agents; Cell Proliferation; Constriction, Pathologic; Disease Models, Animal; Drug-Eluting Stents; Endovascular Procedures; Femoral Artery; Hyperlipoproteinemia Type II; Methacrylates; Neointima; Paclitaxel; Peripheral Arterial Disease; Polymers; Polyvinyls; Prosthesis Design; Recurrence; Sus scrofa; Time Factors; Tomography, Optical Coherence; Vascular Patency; Wound Healing

2017
Protein kinase C inhibitor chelerythrine selectively inhibits proliferation of triple-negative breast cancer cells.
    Scientific reports, 2017, 05-17, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Isoenzymes; Mice; Paclitaxel; Protein Kinase C; Protein Kinase Inhibitors; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2017
Single and combined effects of Δ
    British journal of pharmacology, 2017, Volume: 174, Issue:17

    Topics: Analgesics; Animals; Antineoplastic Agents, Phytogenic; Cannabidiol; Disease Models, Animal; Dronabinol; Drug Therapy, Combination; Hyperalgesia; Male; Mice, Inbred C57BL; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Vincristine

2017
Combination of paclitaxel, bevacizumab and MEK162 in second line treatment in platinum-relapsing patient derived ovarian cancer xenografts.
    Molecular cancer, 2017, 05-30, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bevacizumab; Biomarkers; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Humans; Mice; Mutation; Ovarian Neoplasms; Paclitaxel; Platinum; Recurrence; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays

2017
Free paclitaxel-loaded E-selectin binding peptide modified micelle self-assembled from hyaluronic acid-paclitaxel conjugate inhibit breast cancer metastasis in a murine model.
    International journal of pharmaceutics, 2017, Aug-07, Volume: 528, Issue:1-2

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; E-Selectin; Humans; Hyaluronic Acid; Mice; Micelles; Neoplasm Metastasis; Paclitaxel; Peptides; Polyethylene Glycols

2017
Involvement of Charcot-Marie-Tooth disease gene mitofusin 2 expression in paclitaxel-induced mechanical allodynia in rats.
    Neuroscience letters, 2017, Jul-13, Volume: 653

    Topics: Animals; Antineoplastic Agents, Phytogenic; Charcot-Marie-Tooth Disease; Disease Models, Animal; GTP Phosphohydrolases; Hyperalgesia; Male; Membrane Proteins; Mitochondrial Proteins; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley

2017
Morin promotes prostate cancer cells chemosensitivity to paclitaxel through miR-155/GATA3 axis.
    Oncotarget, 2017, Jul-18, Volume: 8, Issue:29

    Topics: 3' Untranslated Regions; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Cluster Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Flavonoids; GATA3 Transcription Factor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Mice; MicroRNAs; Paclitaxel; Prostatic Neoplasms; RNA Interference; Xenograft Model Antitumor Assays

2017
Therapeutic utility of natural estrogen receptor beta agonists on ovarian cancer.
    Oncotarget, 2017, Jul-25, Volume: 8, Issue:30

    Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Biological Products; Cell Line, Tumor; Cell Movement; Cell Survival; Cisplatin; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Estrogen Receptor beta; Estrogens; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; NF-kappa B; Ovarian Neoplasms; Paclitaxel; Signal Transduction; Xenograft Model Antitumor Assays

2017
Antiallodynic effect of β-caryophyllene on paclitaxel-induced peripheral neuropathy in mice.
    Neuropharmacology, 2017, Volume: 125

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Cannabinoid Receptor Modulators; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Indoles; Male; Neuralgia; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Piperidines; Polycyclic Sesquiterpenes; Pyrazoles; Random Allocation; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sesquiterpenes; Spinal Cord

2017
Therapeutic potential of certain drug combinations on paclitaxel-induced peripheral neuropathy in rats.
    Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2017, Volume: 58, Issue:2

    Topics: Animals; Disease Models, Animal; Drug Combinations; Male; Neuralgia; Paclitaxel; Rats; Rats, Wistar

2017
Rapid
    Theranostics, 2017, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Disease Models, Animal; Drug Therapy, Combination; Epirubicin; Gliosarcoma; Humans; Hydrogels; Infusion Pumps, Implantable; Magnetic Resonance Imaging; Mice; Neoplasm, Residual; Paclitaxel; Secondary Prevention; Survival Analysis; Treatment Outcome; Tumor Cells, Cultured

2017
The anti-cancer effects of itraconazole in epithelial ovarian cancer.
    Scientific reports, 2017, 07-26, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ovarian Epithelial; Cell Proliferation; Disease Models, Animal; Drug Synergism; Endothelial Cells; Female; Heterografts; Itraconazole; Mice; Neoplasm Transplantation; Paclitaxel; Treatment Outcome

2017
Paclitaxel Promotes Cell Apoptosis in Uterine Leiomyomas.
    Pharmacology, 2017, Volume: 100, Issue:5-6

    Topics: Animals; Apoptosis; Disease Models, Animal; Female; Leiomyoma; Mice; Mice, Inbred C57BL; Paclitaxel; Uterus

2017
Effects of a water extract of Lepidium meyenii root in different models of persistent pain in rats.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 2017, Oct-26, Volume: 72, Issue:11-12

    Topics: Administration, Oral; Analgesics; Animals; Chronic Pain; Disease Models, Animal; Hyperalgesia; Injections, Intra-Articular; Iodoacetic Acid; Male; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Palmitic Acids; Phytotherapy; Plant Extracts; Plant Roots; Polyunsaturated Alkamides; Postural Balance; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sciatica; Water

2017
Gene Expression Profiling of Cutaneous Injured and Non-Injured Nociceptors in SNI Animal Model of Neuropathic Pain.
    Scientific reports, 2017, 08-24, Volume: 7, Issue:1

    Topics: Animals; Biopsy; Caspase 6; Computational Biology; Disease Models, Animal; Ganglia, Spinal; Gene Expression Profiling; Humans; Immunohistochemistry; Mice; Mice, Knockout; Neuralgia; Nociceptors; Paclitaxel; Rats; Skin; Spinal Nerves; Transcriptome

2017
Co-delivery of paclitaxel and cetuximab by nanodiamond enhances mitotic catastrophe and tumor inhibition.
    Scientific reports, 2017, 08-29, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cetuximab; Colorectal Neoplasms; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; ErbB Receptors; Gene Expression; Humans; Mitosis; Nanodiamonds; Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays

2017
Combination Cancer Therapy Using Chimeric Antigen Receptor-Engineered Natural Killer Cells as Drug Carriers.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2017, Dec-06, Volume: 25, Issue:12

    Topics: Animals; Antigens, CD19; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cytotoxicity, Immunologic; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Gene Expression; Humans; Immunotherapy; Killer Cells, Natural; Liposomes; Mice; Mice, Knockout; Nanomedicine; Nanoparticles; Neoplasms; Paclitaxel; Receptor, ErbB-2; Receptors, Antigen; Recombinant Fusion Proteins; Treatment Outcome; Xenograft Model Antitumor Assays

2017
YAP transcriptionally regulates COX-2 expression and GCCSysm-4 (G-4), a dual YAP/COX-2 inhibitor, overcomes drug resistance in colorectal cancer.
    Journal of experimental & clinical cancer research : CR, 2017, 10-16, Volume: 36, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Binding Sites; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Genes, Reporter; Humans; Male; Mice; Nuclear Proteins; Paclitaxel; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Transport; Response Elements; Transcription Factors; Transcriptional Activation; Xenograft Model Antitumor Assays

2017
Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN.
    The Journal of pharmacology and experimental therapeutics, 2018, Volume: 364, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Hyperalgesia; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Nicotine; Paclitaxel; Peripheral Nervous System Diseases; Receptors, Cholinergic; Taxoids

2018
Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy.
    eLife, 2017, 11-10, Volume: 6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Carbazoles; Disease Models, Animal; Enzyme Activators; Histocytochemistry; Neuroprotective Agents; Nicotinamide Phosphoribosyltransferase; Paclitaxel; Peripheral Nervous System Diseases; Rats; Treatment Outcome

2017
Effects of WD‑3 on tumor growth and the expression of integrin αvβ3 and ERK1/2 in mice bearing human gastric cancer using the 18F‑RGD PET/CT imaging system.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Fluorodeoxyglucose F18; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaVbeta3; MAP Kinase Signaling System; Medicine, Chinese Traditional; Mice; Paclitaxel; Positron Emission Tomography Computed Tomography; Stomach Neoplasms; Xenograft Model Antitumor Assays

2017
Paclitaxel alleviated liver injury of septic mice by alleviating inflammatory response via microRNA-27a/TAB3/NF-κB signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred C57BL; MicroRNAs; NF-kappa B; Oxidative Stress; Paclitaxel; RNA, Messenger; Sepsis; Signal Transduction; Tumor Necrosis Factor-alpha

2018
Evaluation Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus in Combination With Anticancer Drugs in Human Cancer Orthotopic Mouse Models.
    Integrative cancer therapies, 2018, Volume: 17, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Fucus; Humans; MCF-7 Cells; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Polysaccharides; Tamoxifen; Undaria

2018
Preclinical evaluation of a paclitaxel-incorporated nanoparticle-coated balloon in rabbit and porcine models.
    Cardiovascular revascularization medicine : including molecular interventions, 2018, Volume: 19, Issue:4

    Topics: Animals; Cardiac Catheterization; Cardiac Catheters; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Dimethylpolysiloxanes; Disease Models, Animal; Drug Carriers; Endothelial Cells; Female; Iliac Artery; Male; Materials Testing; Myocytes, Smooth Muscle; Nanoparticles; Paclitaxel; Percutaneous Coronary Intervention; Prosthesis Design; Rabbits; Sus scrofa; Time Factors; Tomography, Optical Coherence

2018
Novel multi‑kinase inhibitor, T03 inhibits Taxol‑resistant breast cancer.
    Molecular medicine reports, 2018, Volume: 17, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Humans; Mice; Paclitaxel; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; raf Kinases; Signal Transduction; Xenograft Model Antitumor Assays

2018
Structure Reconstruction of LyP-1:
    Molecular pharmaceutics, 2018, 02-05, Volume: 15, Issue:2

    Topics: Amides; Animals; Antineoplastic Agents, Phytogenic; Brain; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Female; Humans; Lymphatic Vessels; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Mitochondrial Proteins; Molecular Docking Simulation; Paclitaxel; Peptides, Cyclic; Polyethylene Glycols; Rats; Stereoisomerism

2018
Blocking of cytokines signalling attenuates evoked and spontaneous neuropathic pain behaviours in the paclitaxel rat model of chemotherapy-induced neuropathy.
    European journal of pain (London, England), 2018, Volume: 22, Issue:4

    Topics: Animals; Cytokines; Disease Models, Animal; Etanercept; Interleukin 1 Receptor Antagonist Protein; Male; Neuralgia; Paclitaxel; Rats; Rats, Wistar; Signal Transduction; Up-Regulation

2018
Additional dexamethasone in chemotherapies with carboplatin and paclitaxel could reduce the impaired glycometabolism in rat models.
    BMC cancer, 2018, 01-16, Volume: 18, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Carboplatin; Dexamethasone; Disease Models, Animal; Female; Glucagon; Humans; Hyperglycemia; Insulin; Ovarian Neoplasms; Paclitaxel; Rats

2018
Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy.
    Pain, 2018, Volume: 159, Issue:5

    Topics: Animals; Antineoplastic Agents; Astrocytes; Disease Models, Animal; Female; Ganglia, Spinal; Guanine Nucleotide Exchange Factors; Hydrazones; Hyperalgesia; Isoxazoles; Male; Mice; Mice, Knockout; Nerve Fibers; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Spinal Cord

2018
Evaluation of the Distribution of Paclitaxel After Application of a Paclitaxel-Coated Balloon in the Rabbit Urethra.
    Journal of endourology, 2018, Volume: 32, Issue:5

    Topics: Animals; Catheterization; Constriction, Pathologic; Disease Models, Animal; Drug Delivery Systems; Male; Paclitaxel; Rabbits; Tubulin Modulators; Urethra; Urethral Stricture; Urothelium

2018
Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain.
    European journal of pharmacology, 2018, Mar-15, Volume: 823

    Topics: Amines; Analgesics; Animals; Antineoplastic Agents; Blood Pressure; Cyclohexanecarboxylic Acids; Disease Models, Animal; Fluorobenzenes; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Locomotion; Male; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Peripheral Nervous System; Rats; Rats, Sprague-Dawley

2018
Modulation by hydroxytyrosol of oxidative stress and antitumor activities of paclitaxel in breast cancer.
    European journal of nutrition, 2019, Volume: 58, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Female; Oxidative Stress; Paclitaxel; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome; Tumor Burden

2019
Development and evaluation of novel tumor-targeting paclitaxel-loaded nano-carriers for ovarian cancer treatment: in vitro and in vivo.
    Journal of experimental & clinical cancer research : CR, 2018, Feb-26, Volume: 37, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Liberation; Female; Humans; Mice; Molecular Targeted Therapy; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Polyethylene Glycols; Theranostic Nanomedicine; Xenograft Model Antitumor Assays

2018
Linear Micro-patterned Drug Eluting Balloon (LMDEB) for Enhanced Endovascular Drug Delivery.
    Scientific reports, 2018, 03-05, Volume: 8, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Animals; Atherosclerosis; Chromatography, Liquid; Coronary Angiography; Coronary Restenosis; Disease Models, Animal; Drug Delivery Systems; Drug-Eluting Stents; Iliac Artery; Male; Mass Spectrometry; Microscopy, Confocal; Microscopy, Fluorescence; Paclitaxel; Percutaneous Coronary Intervention; Pressure; Rabbits; Swine; Swine, Miniature; Treatment Outcome

2018
A paclitaxel prodrug with bifunctional folate and albumin binding moieties for both passive and active targeted cancer therapy.
    Theranostics, 2018, Volume: 8, Issue:7

    Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Therapy; Flow Cytometry; Folic Acid; Heterografts; Humans; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Models, Biological; Molecular Targeted Therapy; Neoplasm Transplantation; Paclitaxel; Prodrugs; Protein Binding; Treatment Outcome; Tumor Protein, Translationally-Controlled 1

2018
Cognitive impairment in a rat model of neuropathic pain: role of hippocampal microtubule stability.
    Pain, 2018, Volume: 159, Issue:8

    Topics: Animals; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Learning; Long-Term Potentiation; Male; Memory; Microtubules; Neuralgia; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Tubulin Modulators

2018
Pegylated liposomal‑paclitaxel induces ovarian cancer cell apoptosis via TNF‑induced ERK/AKT signaling pathway.
    Molecular medicine reports, 2018, Volume: 17, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Liposomes; Male; Mice; Paclitaxel; Polyethylene Glycols; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays

2018
[Anti-prostate cancer effect of roemerine: An experimental study].
    Zhonghua nan ke xue = National journal of andrology, 2017, Volume: 23, Issue:1

    Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Drugs, Chinese Herbal; Male; Mice; Mice, Nude; Paclitaxel; Prostatic Neoplasms

2017
Treatment of pancreatic ductal adenocarcinoma with tumor antigen specific-targeted delivery of paclitaxel loaded PLGA nanoparticles.
    BMC cancer, 2018, 04-23, Volume: 18, Issue:1

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents, Immunological; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Liberation; Endocytosis; Female; Gene Expression; Humans; Mice; Molecular Targeted Therapy; Mucin-1; Nanoparticles; Paclitaxel; Pancreatic Neoplasms; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Xenograft Model Antitumor Assays

2018
Combination therapy involving radiofrequency ablation and targeted chemotherapy with bevacizumab plus paclitaxel and cisplatin in a rabbit VX2 lung tumor model.
    BMC research notes, 2018, Apr-24, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents; Bevacizumab; Carcinoma; Catheter Ablation; Cell Line, Tumor; Cisplatin; Combined Modality Therapy; Disease Models, Animal; Drug Therapy, Combination; Female; Lung Neoplasms; Paclitaxel; Rabbits

2018
Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy.
    Journal of immunology (Baltimore, Md. : 1950), 2018, 06-15, Volume: 200, Issue:12

    Topics: Animals; Complement System Proteins; Disease Models, Animal; Hyperalgesia; Immunity, Innate; Nerve Fibers; Neuralgia; Paclitaxel; Peripheral Nervous System Diseases; Quality of Life; Rats; Rats, Inbred F344; Rats, Sprague-Dawley

2018
Nmnat mitigates sensory dysfunction in a
    Disease models & mechanisms, 2018, 06-12, Volume: 11, Issue:6

    Topics: Animals; Cell Count; Dendrites; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Female; Larva; Male; Microtubules; Nicotinamide-Nucleotide Adenylyltransferase; Nociception; Paclitaxel; Peripheral Nervous System Diseases; Sensory Receptor Cells

2018
Regression of Atherosclerotic Plaques of Cholesterol-Fed Rabbits by Combined Chemotherapy With Paclitaxel and Methotrexate Carried in Lipid Core Nanoparticles.
    Journal of cardiovascular pharmacology and therapeutics, 2018, Volume: 23, Issue:6

    Topics: Animals; Aorta; Aortic Diseases; Atherosclerosis; Cardiovascular Agents; Cholesterol, Dietary; Cytokines; Disease Models, Animal; Drug Compounding; Drug Therapy, Combination; Inflammation Mediators; Lipids; Liposomes; Male; Matrix Metalloproteinase 9; Methotrexate; Nanoparticles; Paclitaxel; Plaque, Atherosclerotic; Rabbits

2018
Identification of cardioprotective drugs by medium-scale
    Disease models & mechanisms, 2018, 07-20, Volume: 11, Issue:7

    Topics: Actins; Animals; Cardiotonic Agents; Disease Models, Animal; Drosophila melanogaster; Drug Evaluation, Preclinical; Frataxin; Friedreich Ataxia; Iron-Binding Proteins; Methylene Blue; Microtubules; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Myosins; Paclitaxel; Reproducibility of Results; Sarcomeres; Small Molecule Libraries

2018
The Effect of the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid and Paclitaxel Treatment on Full-Thickness Wound Healing in Mice.
    Annals of plastic surgery, 2018, Volume: 81, Issue:4

    Topics: Animals; Back Injuries; Disease Models, Animal; Histone Deacetylase Inhibitors; Mice; Mice, Nude; Paclitaxel; Vorinostat; Wound Healing

2018
Mechanisms of enhanced antiglioma efficacy of polysorbate 80-modified paclitaxel-loaded PLGA nanoparticles by focused ultrasound.
    Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apolipoproteins E; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain Neoplasms; Disease Models, Animal; Drug Compounding; Drug Delivery Systems; Drug Liberation; Extracorporeal Shockwave Therapy; Female; Gene Expression; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Polysorbates; Survival Analysis; Tight Junctions

2018
Evoked and Ongoing Pain-Like Behaviours in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy.
    Pain research & management, 2018, Volume: 2018

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Hyperalgesia; Male; Motor Activity; Neuralgia; Paclitaxel; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Psychomotor Performance; Random Allocation; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors

2018
Differential Morphological and Biochemical Recovery from Chemotherapy-Induced Peripheral Neuropathy Following Paclitaxel, Ixabepilone, or Eribulin Treatment in Mouse Sciatic Nerves.
    Neurotoxicity research, 2018, Volume: 34, Issue:3

    Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Epothilones; Female; Furans; Intermediate Filaments; Ketones; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Myelin Sheath; Paclitaxel; Recovery of Function; S100 Proteins; Schwann Cells; Sciatic Neuropathy; Time Factors; Tubulin

2018
A novel approach to monitoring the efficacy of anti-tumor treatments in animal models: combining functional MRI and texture analysis.
    BMC cancer, 2018, Aug-20, Volume: 18, Issue:1

    Topics: Allografts; Animals; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Contrast Media; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Animal; Mice; Paclitaxel; Treatment Outcome

2018
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels.
    Pain, 2019, Volume: 160, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Calcium Channels, N-Type; Calcium Channels, T-Type; CHO Cells; Cricetulus; Diprenorphine; Disease Models, Animal; Female; Ganglia, Spinal; HIV Infections; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Neuralgia; Neurons; Paclitaxel; Pentacyclic Triterpenes; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Triterpenes; Tritium

2019
Beneficial effects of Gelsemium-based treatment against paclitaxel-induced painful symptoms.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2018, Volume: 39, Issue:12

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dose-Response Relationship, Drug; Gelsemium; Hyperalgesia; Male; Paclitaxel; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Plant Extracts; Rats; Rats, Sprague-Dawley; Sciatic Nerve

2018
Paclitaxel-coated stents to prevent hyperplastic proliferation of ureteral tissue: from in vitro to in vivo.
    Urolithiasis, 2020, Volume: 48, Issue:1

    Topics: Animals; Cell Line; Cell Proliferation; Disease Models, Animal; Drug-Eluting Stents; Epithelial Cells; Humans; Hyperplasia; Male; Paclitaxel; Rats; Ureter; Ureteral Obstruction; Urothelium

2020
Monitoring Early Breast Cancer Response to Neoadjuvant Therapy Using H-Scan Ultrasound Imaging: Preliminary Preclinical Results.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2019, Volume: 38, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease Models, Animal; Female; Mice; Mice, Nude; Neoadjuvant Therapy; Paclitaxel; Phantoms, Imaging; Treatment Outcome; Ultrasonography

2019
In vivo metabolic and SHG imaging for monitoring of tumor response to chemotherapy.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2019, Volume: 95, Issue:1

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor; Cisplatin; Collagen; Colorectal Neoplasms; Disease Models, Animal; Female; Irinotecan; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence, Multiphoton; NADP; Paclitaxel; Second Harmonic Generation Microscopy

2019
Enhanced bioreduction-responsive diselenide-based dimeric prodrug nanoparticles for triple negative breast cancer therapy.
    Theranostics, 2018, Volume: 8, Issue:18

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Heterografts; Humans; Mice, Nude; Models, Theoretical; Molecular Targeted Therapy; Nanoparticles; Neoplasm Transplantation; Oxidation-Reduction; Paclitaxel; Prodrugs; Selenium Compounds; Treatment Outcome; Triple Negative Breast Neoplasms

2018
Monoclonal Antibody Targeting the Matrix Metalloproteinase 9 Prevents and Reverses Paclitaxel-Induced Peripheral Neuropathy in Mice.
    The journal of pain, 2019, Volume: 20, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Cells, Cultured; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; Immunologic Factors; Male; Matrix Metalloproteinase 9; Mice; Neuralgia; Neurons; Neuroprotective Agents; Paclitaxel; Peripheral Nervous System Diseases

2019
Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery.
    EBioMedicine, 2018, Volume: 38

    Topics: Animals; Antineoplastic Agents; Biomarkers; Carcinoma, Pancreatic Ductal; Cell Line; Disease Models, Animal; Endothelium, Lymphatic; Female; Humans; Immunohistochemistry; Lymph Nodes; Male; Mice; Molecular Targeted Therapy; Nanoparticles; Neovascularization, Pathologic; Paclitaxel; Pancreatic Neoplasms; Theranostic Nanomedicine; Xenograft Model Antitumor Assays

2018
Pre- and post-operative anti-PD-L1 plus anti-angiogenic therapies in mouse breast or renal cancer models of micro- or macro-metastatic disease.
    British journal of cancer, 2019, Volume: 120, Issue:2

    Topics: Animals; B7-H1 Antigen; Bevacizumab; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Immunotherapy; Kidney Neoplasms; Mammary Neoplasms, Animal; Mice; Neoadjuvant Therapy; Neovascularization, Pathologic; Paclitaxel; Sunitinib

2019
Mesenchymal stem cells therapy enhances the efficacy of pregabalin and prevents its motor impairment in paclitaxel-induced neuropathy in rats: Role of Notch1 receptor and JAK/STAT signaling pathway.
    Behavioural brain research, 2019, 03-15, Volume: 360

    Topics: Acetone; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Caspase 3; Cell- and Tissue-Based Therapy; Disease Models, Animal; Hyperalgesia; Interleukin-6; Janus Kinases; Male; Mesenchymal Stem Cells; Motor Disorders; Nerve Growth Factor; Paclitaxel; Pregabalin; Rats; Rats, Wistar; Receptor, Notch1; Rotarod Performance Test; Sciatic Neuropathy; STAT Transcription Factors; Time Factors; Tumor Necrosis Factor-alpha

2019
Targeting cancer stem cell signature gene SMOC-2 Overcomes chemoresistance and inhibits cell proliferation of endometrial carcinoma.
    EBioMedicine, 2019, Volume: 40

    Topics: Animals; Biomarkers; Calcium-Binding Proteins; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Mice; Neoplasm Grading; Neoplasm Staging; Neoplastic Stem Cells; Paclitaxel; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2019
Stereocomplex micelle loaded with paclitaxel for enhanced therapy of breast cancer in an orthotopic mouse model.
    Journal of biomaterials science. Polymer edition, 2019, Volume: 30, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Dextrans; Disease Models, Animal; Drug Carriers; Female; Humans; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Particle Size; Polyesters; Surface Properties; Tissue Distribution

2019
The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 111

    Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Disease Models, Animal; Female; Gemcitabine; Humans; Mice; Mice, Nude; Middle Aged; Paclitaxel; Sarcoma; Treatment Outcome; Xenograft Model Antitumor Assays

2019
Therapeutic impact of Nintedanib with paclitaxel and/or a PD-L1 antibody in preclinical models of orthotopic primary or metastatic triple negative breast cancer.
    Journal of experimental & clinical cancer research : CR, 2019, Jan-11, Volume: 38, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Immunological; B7-H1 Antigen; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Indoles; Kaplan-Meier Estimate; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Paclitaxel; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2019
A peptide-modified solid lipid nanoparticle formulation of paclitaxel modulates immunity and outperforms dacarbazine in a murine melanoma model.
    Biomaterials science, 2019, Feb-26, Volume: 7, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Calreticulin; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cytokines; Dacarbazine; Disease Models, Animal; Female; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Nanoparticles; Paclitaxel; Peptides; Survival Rate; Tissue Distribution

2019
Circulating microRNA and automated motion analysis as novel methods of assessing chemotherapy-induced peripheral neuropathy in mice.
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Automation; Behavior, Animal; Biomarkers; Circulating MicroRNA; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Movement; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases; Sciatic Nerve

2019
Evodiamine ameliorates paclitaxel-induced neuropathic pain by inhibiting inflammation and maintaining mitochondrial anti-oxidant functions.
    Human cell, 2019, Volume: 32, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cytokines; Disease Models, Animal; Ganglia, Spinal; Humans; Inflammation Mediators; Male; Membrane Potential, Mitochondrial; Mitochondria; Neuralgia; Oxidative Stress; Paclitaxel; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phytotherapy; Quinazolines; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Cells, Cultured; Uncoupling Protein 2

2019
Cisplatin educates CD8+ T cells to prevent and resolve chemotherapy-induced peripheral neuropathy in mice.
    Pain, 2019, Volume: 160, Issue:6

    Topics: Animals; Antineoplastic Agents; CD8-Positive T-Lymphocytes; Cisplatin; Disease Models, Animal; Female; Hyperalgesia; Male; Mice, Transgenic; Paclitaxel; Pain; Peripheral Nervous System Diseases

2019
Paclitaxel Enhances the Innate Immunity by Promoting NLRP3 Inflammasome Activation in Macrophages.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Acetylation; Acetyltransferases; Animals; Bacterial Infections; Cell Line; Disease Models, Animal; Epothilones; Gene Knockdown Techniques; Humans; Immunity, Innate; Inflammasomes; Interleukin-1beta; Macrophages; Mice; Microtubule Proteins; Microtubules; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Paclitaxel; Pyroptosis; Signal Transduction; THP-1 Cells; Tubulin

2019
MSC-Delivered Soluble TRAIL and Paclitaxel as Novel Combinatory Treatment for Pancreatic Adenocarcinoma.
    Theranostics, 2019, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell- and Tissue-Based Therapy; Combined Modality Therapy; Disease Models, Animal; Humans; Mesenchymal Stem Cells; Mice, Nude; Models, Theoretical; Neoplasm Transplantation; Paclitaxel; Pancreatic Neoplasms; TNF-Related Apoptosis-Inducing Ligand; Transplantation, Heterologous; Treatment Outcome

2019
Prevention of cancer dormancy by Fbxw7 ablation eradicates disseminated tumor cells.
    JCI insight, 2019, 02-21, Volume: 4, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bone Marrow; Bone Marrow Cells; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cohort Studies; Datasets as Topic; Disease Models, Animal; Drug Resistance, Neoplasm; F-Box-WD Repeat-Containing Protein 7; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Kaplan-Meier Estimate; MCF-7 Cells; Mice; Neoplasm Recurrence, Local; Paclitaxel; Prognosis; Spheroids, Cellular; Xenograft Model Antitumor Assays

2019
Differential effect of LPS and paclitaxel on microglial functional phenotypes and circulating cytokines: the possible role of CX3CR1 and IL-4/10 in blocking persistent inflammation.
    Archives of pharmacal research, 2019, Volume: 42, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; CX3C Chemokine Receptor 1; Disease Models, Animal; Inflammation; Interleukin-10; Interleukin-4; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Neuralgia; Paclitaxel; Phenotype

2019
A fruit fly model for studying paclitaxel-induced peripheral neuropathy and hyperalgesia.
    F1000Research, 2018, Volume: 7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Disease Models, Animal; Drosophila melanogaster; Female; Male; Nociception; Paclitaxel

2018
Indomethacin plus minocycline coadministration relieves chemotherapy and antiretroviral drug-induced neuropathic pain in a cannabinoid receptors-dependent manner.
    Journal of pharmacological sciences, 2019, Volume: 139, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Retroviral Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Female; Indomethacin; Mice, Inbred BALB C; Minocycline; Neuralgia; Paclitaxel; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Zalcitabine

2019
An Experimental Study of Paclitaxel Embolisation During Drug Coated Balloon Angioplasty.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2019, Volume: 57, Issue:4

    Topics: Angioplasty, Balloon; Animals; Chemoembolization, Therapeutic; Coated Materials, Biocompatible; Disease Models, Animal; Femoral Artery; Male; Paclitaxel; Peripheral Arterial Disease; Popliteal Artery; Rabbits; Renal Artery; Treatment Outcome

2019
Magnetophoretic Delivery of a Tumor-Priming Agent for Chemotherapy of Metastatic Murine Breast Cancer.
    Molecular pharmaceutics, 2019, 05-06, Volume: 16, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Drug Liberation; Female; Ferric Compounds; Injections, Intravenous; Magnetite Nanoparticles; Mice; Mice, Inbred BALB C; Paclitaxel; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome; Tumor Burden; Tumor Microenvironment

2019
Exosomes from M1-Polarized Macrophages Enhance Paclitaxel Antitumor Activity by Activating Macrophages-Mediated Inflammation.
    Theranostics, 2019, Volume: 9, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Exosomes; Immunologic Factors; Macrophage Activation; Macrophages; Mice; Paclitaxel; Treatment Outcome

2019
Losartan, an Angiotensin II Type 1 Receptor Antagonist, Alleviates Mechanical Hyperalgesia in a Rat Model of Chemotherapy-Induced Neuropathic Pain by Inhibiting Inflammatory Cytokines in the Dorsal Root Ganglia.
    Molecular neurobiology, 2019, Volume: 56, Issue:11

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cytokines; Disease Models, Animal; Ganglia, Spinal; Glial Fibrillary Acidic Protein; Hyperalgesia; Hypnotics and Sedatives; Inflammation Mediators; Losartan; Male; Neuralgia; Neurons; NF-kappa B; Paclitaxel; Phosphorylation; Rats, Sprague-Dawley

2019
The Preparation, Determination of a Flexible Complex Liposome Co-Loaded with Cabazitaxel and β-Elemene, and Animal Pharmacodynamics on Paclitaxel-Resistant Lung Adenocarcinoma.
    Molecules (Basel, Switzerland), 2019, Apr-30, Volume: 24, Issue:9

    Topics: Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; Liposomes; Mice; Molecular Structure; Paclitaxel; Particle Size; Sesquiterpenes; Taxoids; Tumor Burden; Xenograft Model Antitumor Assays

2019
Carboplatin/paclitaxel, E7-vaccination and intravaginal CpG as tri-therapy towards efficient regression of genital HPV16 tumors.
    Journal for immunotherapy of cancer, 2019, 05-06, Volume: 7, Issue:1

    Topics: Administration, Intravaginal; Animals; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Combined Modality Therapy; Disease Models, Animal; Female; Genital Neoplasms, Female; Human papillomavirus 16; Humans; Immunotherapy; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Oligodeoxyribonucleotides; Paclitaxel; Papillomavirus E7 Proteins; Papillomavirus Infections; Toll-Like Receptor 9; Vaccines, Synthetic; Vagina

2019
Effective Delivery of a Microtubule Polymerization Inhibitor Synergizes with Standard Regimens in Models of Pancreatic Ductal Adenocarcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 09-15, Volume: 25, Issue:18

    Topics: Albumins; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gemcitabine; Humans; Immunohistochemistry; Mice; Microtubules; Paclitaxel; Pancreatic Neoplasms; Protein Multimerization; Tubulin Modulators; Xenograft Model Antitumor Assays

2019
Nano-drug System Based on Hierarchical Drug Release for Deep Localized/Systematic Cascade Tumor Therapy Stimulating Antitumor Immune Responses.
    Theranostics, 2019, Volume: 9, Issue:10

    Topics: Animals; Antineoplastic Agents; Carcinoma; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Drug Liberation; Drug Therapy; Gold; HeLa Cells; Humans; Hyperthermia, Induced; Immunologic Factors; Immunotherapy; Mice; Models, Biological; Nanocomposites; Neoplasm Transplantation; Paclitaxel; Photosensitizing Agents; Phototherapy; Transplantation, Heterologous; Treatment Outcome

2019
Long noncoding RNA CASC2 promotes paclitaxel resistance in breast cancer through regulation of miR-18a-5p/CDK19.
    Histochemistry and cell biology, 2019, Volume: 152, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kinases; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Paclitaxel; RNA, Long Noncoding

2019
Cathepsin L-mediated resistance of paclitaxel and cisplatin is mediated by distinct regulatory mechanisms.
    Journal of experimental & clinical cancer research : CR, 2019, Aug-01, Volume: 38, Issue:1

    Topics: Animals; Antineoplastic Agents; Cathepsin L; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Drug Resistance, Neoplasm; Early Growth Response Protein 1; Genes, Reporter; Humans; Male; Paclitaxel; Promoter Regions, Genetic; Protein Binding; Smad3 Protein; Xenograft Model Antitumor Assays

2019
Intravenous administration of manuka honey inhibits tumor growth and improves host survival when used in combination with chemotherapy in a melanoma mouse model.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Administration, Intravenous; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Honey; Humans; Leptospermum; Male; Melanoma; Mice; Necrosis; Paclitaxel; Tumor Burden

2013
The effect of short-term intra-arterial delivery of paclitaxel on neointimal hyperplasia and the local thrombotic environment after angioplasty.
    Cardiovascular and interventional radiology, 2013, Volume: 36, Issue:4

    Topics: Angioplasty, Balloon; Animals; Biopsy, Needle; Carotid Artery Injuries; Carotid Artery, Common; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Hyperplasia; Immunohistochemistry; Infusions, Intra-Arterial; Male; Neointima; Paclitaxel; Random Allocation; Rats; Rats, Wistar; Risk Assessment; Thromboplastin; Thrombosis; Time Factors; Tissue Plasminogen Activator; Treatment Outcome

2013
HDAC6 mutations rescue human tau-induced microtubule defects in Drosophila.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Mar-19, Volume: 110, Issue:12

    Topics: Alzheimer Disease; Animals; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Epothilones; Histone Deacetylase 6; Histone Deacetylases; Humans; Mice; Mice, Knockout; Microtubules; Muscle Cells; Mutation; Neurons; Paclitaxel; Phosphorylation; tau Proteins; Tubulin Modulators

2013
Combined delivery of paclitaxel and tanespimycin via micellar nanocarriers: pharmacokinetics, efficacy and metabolomic analysis.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Benzoquinones; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Female; Humans; Lactams, Macrocyclic; Metabolome; Metabolomics; Mice; Micelles; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Spectroscopy, Near-Infrared; Tumor Burden; Xenograft Model Antitumor Assays

2013
Cutting balloon combined with paclitaxel-eluting balloon for treatment of in-stent restenosis.
    Archives of cardiovascular diseases, 2013, Volume: 106, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Animals; Apoptosis; Cardiac Catheters; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Equipment Design; Immunohistochemistry; In Situ Nick-End Labeling; Metals; Muscle, Smooth, Vascular; Neointima; Paclitaxel; Prosthesis Design; Stents; Swine; Swine, Miniature; Time Factors

2013
Effects of repeated milnacipran and fluvoxamine treatment on mechanical allodynia in a mouse paclitaxel-induced neuropathic pain model.
    Biomedical research (Tokyo, Japan), 2013, Volume: 34, Issue:2

    Topics: Animals; Cyclopropanes; Disease Models, Animal; Fluvoxamine; Hyperalgesia; Male; Mice; Milnacipran; Neuralgia; Paclitaxel

2013
TLR4 is a novel determinant of the response to paclitaxel in breast cancer.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Autocrine Communication; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Cytokine; Toll-Like Receptor 4; Transcriptional Activation

2013
The effect of antineoplastic drugs in a male spontaneous mammary tumor model.
    PloS one, 2014, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Proliferation; Cisplatin; Disease Models, Animal; Female; Male; Mammary Neoplasms, Experimental; Mice, Transgenic; Neoplasm Proteins; Paclitaxel; Phenotype; Receptors, Estrogen; Receptors, Progesterone

2014
Ovarian tumor initiating cell populations persist following paclitaxel and carboplatin chemotherapy treatment in vivo.
    Cancer letters, 2013, Oct-10, Volume: 339, Issue:2

    Topics: AC133 Antigen; Animals; Antigens, CD; Antigens, Ly; Antineoplastic Agents; Carboplatin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Gene Expression; Glycoproteins; Membrane Proteins; Mice; Neoplastic Stem Cells; Ovarian Neoplasms; Paclitaxel; Peptides; Tumor Burden

2013
Comparative benefits of Nab-paclitaxel over gemcitabine or polysorbate-based docetaxel in experimental pancreatic cancer.
    Carcinogenesis, 2013, Volume: 34, Issue:10

    Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Disease Models, Animal; Docetaxel; Female; Gemcitabine; Humans; Inhibitory Concentration 50; Neoplasms, Experimental; Paclitaxel; Pancreatic Neoplasms; Stathmin; Stromal Cells; Taxoids; Tubulin; Tumor Burden; Xenograft Model Antitumor Assays

2013
Integrity of stent polymer layer after drug-eluting stent implantation: in vivo comparison of sirolimus-, paclitaxel-, zotarolimus- and everolimus-eluting stents.
    Cardiovascular intervention and therapeutics, 2014, Volume: 29, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Vessel Prosthesis Implantation; Coated Materials, Biocompatible; Coronary Restenosis; Disease Models, Animal; Drug-Eluting Stents; Everolimus; Immunosuppressive Agents; Paclitaxel; Prosthesis Design; Sirolimus; Swine

2014
A bioengineered 3D ovarian cancer model for the assessment of peptidase-mediated enhancement of spheroid growth and intraperitoneal spread.
    Biomaterials, 2013, Volume: 34, Issue:30

    Topics: Animals; Bioengineering; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Mice; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Paclitaxel; Peptide Hydrolases; Peritoneum; Spheroids, Cellular

2013
[The pilot study of the effect of paclitaxel by local application on scar formation after airway injury in rabbits].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2013, Volume: 36, Issue:3

    Topics: Administration, Topical; Animals; Apoptosis; Cicatrix; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Male; Paclitaxel; Pilot Projects; Rabbits; Random Allocation; Trachea; Tracheal Stenosis; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A

2013
Metformin impairs endothelialization after placement of newer generation drug eluting stents.
    Atherosclerosis, 2013, Volume: 229, Issue:2

    Topics: Angioplasty, Balloon; Animals; Disease Models, Animal; Drug-Eluting Stents; Endothelium, Vascular; Everolimus; Hypoglycemic Agents; Iliac Artery; Immunosuppressive Agents; Male; Metformin; Paclitaxel; Rabbits; Sirolimus; Thrombosis; Tubulin Modulators

2013
Stromal disrupting effects of nab-paclitaxel in pancreatic cancer.
    British journal of cancer, 2013, Aug-20, Volume: 109, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Collagen; Deoxycytidine; Disease Models, Animal; Elasticity Imaging Techniques; Endosonography; Female; Fibroblasts; Gemcitabine; Humans; Male; Mice; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Pancreatic Neoplasms; Positron-Emission Tomography

2013
A preliminary study of imaging paclitaxel-induced tumor apoptosis with (99)Tc(m)-His10-Annexin V.
    Chinese medical journal, 2013, Volume: 126, Issue:15

    Topics: Animals; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Histidine; Humans; Lung Neoplasms; Mice; Organotechnetium Compounds; Paclitaxel; Radiopharmaceuticals

2013
Carrier-free functionalized multidrug nanorods for synergistic cancer therapy.
    Biomaterials, 2013, Volume: 34, Issue:35

    Topics: Animals; Camptothecin; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Drug Synergism; Drug Therapy, Combination; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; KB Cells; MCF-7 Cells; Methotrexate; Mice; Mice, Inbred BALB C; Nanoparticles; Nanotubes; Neoplasms; Paclitaxel

2013
Stent healing response following delivery of paclitaxel via durable polymeric matrix versus iopromide-based balloon coating in the familial hypercholesterolaemic swine model of coronary injury.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2013, Aug-22, Volume: 9, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Animals; Cardiovascular Agents; Constriction, Pathologic; Coronary Artery Disease; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Iohexol; Neointima; Paclitaxel; Polymers; Swine

2013
Tissue uptake, distribution, and healing response after delivery of paclitaxel via second-generation iopromide-based balloon coating: a comparison with the first-generation technology in the iliofemoral porcine model.
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:8

    Topics: Angioplasty, Balloon; Animals; Arterial Occlusive Diseases; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Constriction, Pathologic; Contrast Media; Disease Models, Animal; Equipment Design; Femoral Artery; Fibrosis; Hyperlipoproteinemia Type II; Iliac Artery; Iohexol; Neointima; Paclitaxel; Radiography; Sus scrofa; Tissue Distribution; Vascular Access Devices; Wound Healing

2013
Janus nanogels of PEGylated Taxol and PLGA-PEG-PLGA copolymer for cancer therapy.
    Nanoscale, 2013, Oct-21, Volume: 5, Issue:20

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Disease Models, Animal; Doxorubicin; Drug Carriers; Drug Therapy, Combination; Female; Half-Life; Mice; Mice, Inbred BALB C; Nanogels; Paclitaxel; Polyethylene Glycols; Polyethyleneimine; Polyglactin 910

2013
Nab-paclitaxel is an active drug in preclinical model of pediatric solid tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Nov-01, Volume: 19, Issue:21

    Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Female; Humans; Mice; Neoplasms; Neuroblastoma; Osteosarcoma; Paclitaxel; Rhabdomyosarcoma; Xenograft Model Antitumor Assays

2013
The dual PI3K/mTOR inhibitor NVP-BEZ235 enhances nab-paclitaxel antitumor response in experimental gastric cancer.
    International journal of oncology, 2013, Volume: 43, Issue:5

    Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Disease Models, Animal; Drug Synergism; Female; Humans; Imidazoles; Mice; Mice, Inbred NOD; Mice, SCID; Nanoparticles; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinolines; Stomach Neoplasms; Tumor Cells, Cultured

2013
Microtubule-stabilizing agents delay the onset of EAE through inhibition of migration.
    Immunology and cell biology, 2013, Volume: 91, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autoantigens; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Disease Progression; Docetaxel; Drug Synergism; Encephalomyelitis, Autoimmune, Experimental; Epothilones; Growth Inhibitors; Humans; Lactones; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubules; Multiple Sclerosis; Paclitaxel; Taxoids

2013
Static magnetic fields increase tumor microvessel leakiness and improve antitumoral efficacy in combination with paclitaxel.
    Cancer letters, 2014, Feb-01, Volume: 343, Issue:1

    Topics: Albumins; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Combined Modality Therapy; Disease Models, Animal; Endothelial Cells; Leukocytes; Magnetic Fields; Male; Mesocricetus; Microcirculation; Microscopy, Fluorescence; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Permeability

2014
Tumor targeting effects of a novel modified paclitaxel-loaded discoidal mimic high density lipoproteins.
    Drug delivery, 2013, Volume: 20, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biomimetic Materials; Breast Neoplasms; Cholesterol Esters; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Humans; Lipoproteins, HDL; Male; MCF-7 Cells; Mice; Mice, Inbred ICR; Paclitaxel; Particle Size; Phosphatidylcholine-Sterol O-Acyltransferase; Tissue Distribution

2013
Novel isoprenoyl nanoassembled prodrug for paclitaxel delivery.
    Bioconjugate chemistry, 2013, Nov-20, Volume: 24, Issue:11

    Topics: Animals; Antineoplastic Agents; Body Weight; Butadienes; Disease Models, Animal; Disease Progression; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Hemiterpenes; Humans; Inhibitory Concentration 50; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Pentanes; Prodrugs; Tumor Cells, Cultured

2013
The significance of microscopic mass spectrometry with high resolution in the visualisation of drug distribution.
    Scientific reports, 2013, Oct-25, Volume: 3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Monitoring; Female; Mass Spectrometry; Mice; Microscopy; Neoplasms; Paclitaxel; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tissue Distribution; Tumor Burden

2013
Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer.
    Breast cancer research : BCR, 2013, Volume: 15, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression; Gene Knockdown Techniques; Humans; Inhibitor of Apoptosis Proteins; Mice; Paclitaxel; Receptor, ErbB-2; Receptor, ErbB-3; Survivin; Trastuzumab; Tumor Burden; Xenograft Model Antitumor Assays

2013
Inhibition of neo-intimal hyperplasia in porcine coronary arteries utilizing a novel paclitaxel-coated scoring balloon catheter.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2014, Dec-01, Volume: 84, Issue:7

    Topics: Angioplasty, Balloon, Coronary; Animals; Antineoplastic Agents, Phytogenic; Cardiac Catheters; Coated Materials, Biocompatible; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Equipment Design; Hyperplasia; Male; Paclitaxel; Swine; Tunica Intima

2014
Establishment of paclitaxel-resistant breast cancer cell line and nude mice models, and underlying multidrug resistance mechanisms in vitro and in vivo.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Culture Techniques; Cell Cycle; Cell Proliferation; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Tumor Cells, Cultured

2013
Chemical renal denervation in the rat.
    Cardiovascular and interventional radiology, 2014, Volume: 37, Issue:1

    Topics: Animals; Chromatography, Liquid; Denervation; Disease Models, Animal; Dose-Response Relationship, Drug; Guanethidine; Hypertension; Kidney; Mass Spectrometry; Norepinephrine; Paclitaxel; Phenol; Rats; Rats, Sprague-Dawley; Salicylic Acid; Saline Solution, Hypertonic

2014
Combinations of TLR ligands: a promising approach in cancer immunotherapy.
    Clinical & developmental immunology, 2013, Volume: 2013

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Imidazoles; Immunomodulation; Immunotherapy; Ligands; Lymphocytes; Mice; Neoplasms; Paclitaxel; Poly I-C; Toll-Like Receptors; Tumor Burden; Xenograft Model Antitumor Assays

2013
[Study of claudin-4 in the diagnosis and treatment of endometrial carcinoma].
    Zhonghua fu chan ke za zhi, 2013, Volume: 48, Issue:10

    Topics: Animals; Cell Line, Tumor; Cisplatin; Claudin-4; Disease Models, Animal; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Real-Time Polymerase Chain Reaction; RNA, Messenger; Transplantation, Heterologous

2013
Broad spectrum and prolonged efficacy of dimiracetam in models of neuropathic pain.
    Neuropharmacology, 2014, Volume: 81

    Topics: Analysis of Variance; Animals; Anti-Retroviral Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Hyperalgesia; Imidazoles; Male; Neuralgia; Osteoarthritis, Knee; Paclitaxel; Pain Measurement; Pain Threshold; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vincristine; Weight-Bearing

2014
Experimental development of an intra-abdominal chemohyperthermia model using a closed abdomen technique and a PRS-1.0 Combat CO2 recirculation system.
    Surgery, 2014, Volume: 155, Issue:4

    Topics: Abdomen; Animals; Antineoplastic Agents; Blood Gas Analysis; Body Temperature; Carbon Dioxide; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Disease Models, Animal; Female; Hemodynamics; Hyperthermia, Induced; Infusions, Parenteral; Paclitaxel; Peritoneal Neoplasms; Swine; Treatment Outcome

2014
The TrkB+ cancer stem cells contribute to post-chemotherapy recurrence of triple-negative breast cancers in an orthotopic mouse model.
    Oncogene, 2015, Feb-05, Volume: 34, Issue:6

    Topics: Aged; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Factor 4; Membrane Glycoproteins; Mice; Middle Aged; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Paclitaxel; Paracrine Communication; Protein-Tyrosine Kinases; Receptor, trkB; Signal Transduction; Triple Negative Breast Neoplasms

2015
Paclitaxel coating on the terminal portion of hemodialysis grafts effectively suppresses neointimal hyperplasia in a porcine model.
    Journal of vascular surgery, 2015, Volume: 61, Issue:6

    Topics: Animals; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Cardiovascular Agents; Carotid Artery, Common; Coated Materials, Biocompatible; Constriction, Pathologic; Disease Models, Animal; Female; Graft Occlusion, Vascular; Hyperplasia; Jugular Veins; Neointima; Paclitaxel; Polytetrafluoroethylene; Prosthesis Design; Renal Dialysis; Swine; Time Factors

2015
Enhancement of nab-paclitaxel antitumor activity through addition of multitargeting antiangiogenic agents in experimental pancreatic cancer.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:5

    Topics: Albumins; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Synergism; Female; Humans; Mice; Paclitaxel; Pancreatic Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2014
Translymphatic chemotherapy targeting sentinel lymph nodes using a novel phospholipid polymer-Paclitaxel conjugate.
    Anticancer research, 2014, Volume: 34, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Lymph Nodes; Lymphatic Metastasis; Male; Methacrylates; Neoplasms; Paclitaxel; Phosphorylcholine; Rats; Sentinel Lymph Node Biopsy

2014
Gamma-Fe2O3 nanoparticles increase therapeutic efficacy of combination with paclitaxel and anti-ABCG2 monoclonal antibody on multiple myeloma cancer stem cells in mouse model.
    Journal of biomedical nanotechnology, 2014, Volume: 10, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caspases; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Humans; Magnetite Nanoparticles; Mice; Multiple Myeloma; Neoplasm Proteins; Neoplastic Stem Cells; NF-kappa B; Paclitaxel; Particle Size; Signal Transduction; Succimer; Tumor Burden

2014
Prophylactic cannabinoid administration blocks the development of paclitaxel-induced neuropathic nociception during analgesic treatment and following cessation of drug delivery.
    Molecular pain, 2014, Apr-18, Volume: 10

    Topics: Analgesics; Animals; Antineoplastic Agents, Phytogenic; Cannabinoids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hyperalgesia; Male; Motor Activity; Neuralgia; Paclitaxel; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Cord

2014
Toll-like receptor 4 signaling contributes to Paclitaxel-induced peripheral neuropathy.
    The journal of pain, 2014, Volume: 15, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Male; Myeloid Differentiation Factor 88; Nerve Tissue Proteins; Neurons; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Polysaccharides; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Toll-Like Receptor 4

2014
Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal.
    Biological psychiatry, 2015, Mar-01, Volume: 77, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Chemokine CCL2; Chromones; Disease Models, Animal; Dronabinol; Female; Hyperalgesia; Indoles; Male; Mice, Inbred C57BL; Mice, Knockout; Paclitaxel; Random Allocation; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; Spinal Cord; Tumor Necrosis Factor-alpha

2015
Mechanisms promoting escape from mitotic stress-induced tumor cell death.
    Cancer research, 2014, Jul-15, Volume: 74, Issue:14

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Heterografts; Humans; Lung Neoplasms; Mice; Microtubules; Mitosis; Paclitaxel; Protein Binding; RNA Interference; Spindle Apparatus; Stress, Physiological; Tripartite Motif Proteins; Tumor Burden; Ubiquitin-Protein Ligases

2014
The anti-diabetic drug metformin protects against chemotherapy-induced peripheral neuropathy in a mouse model.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Animals; Cisplatin; Disease Models, Animal; Hyperalgesia; Hypoglycemic Agents; Metformin; Mice, Inbred C57BL; Nerve Fibers; Neuralgia; Paclitaxel; Peripheral Nervous System Diseases; Protective Agents

2014
PEG-farnesyl thiosalicylic acid telodendrimer micelles as an improved formulation for targeted delivery of paclitaxel.
    Molecular pharmaceutics, 2014, Aug-04, Volume: 11, Issue:8

    Topics: Animals; Breast Neoplasms; Disease Models, Animal; Drug Carriers; Farnesol; Female; HCT116 Cells; Hemolysis; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Polyethylene Glycols; Salicylates

2014
Independent evaluation of the anatomical and behavioral effects of Taxol in rat models of spinal cord injury.
    Experimental neurology, 2014, Volume: 261

    Topics: Amino Acids, Diamino; Analysis of Variance; Animals; Antigens; Blood-Brain Barrier; Collagen Type IV; Disease Models, Animal; Female; Fibronectins; Gene Expression Regulation; Motor Activity; Paclitaxel; Proteoglycans; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Time Factors; Tubulin Modulators

2014
Determining the mechanisms of lapatinib-induced diarrhoea using a rat model.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Disease Models, Animal; ErbB Receptors; Goblet Cells; Intestinal Mucosa; Intestines; Lapatinib; Male; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Wistar; Receptor, ErbB-2

2014
A new 2α,5α,10β,14β-tetraacetoxy-4(20),11-taxadiene (SIA) derivative overcomes paclitaxel resistance by inhibiting MAPK signaling and increasing paclitaxel accumulation in breast cancer cells.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Acetates; Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Diterpenes; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; MAP Kinase Signaling System; Paclitaxel; Xenograft Model Antitumor Assays

2014
Involvement of the chemokine CCL3 and the purinoceptor P2X7 in the spinal cord in paclitaxel-induced mechanical allodynia.
    Molecular pain, 2014, Aug-15, Volume: 10

    Topics: Animals; Antibodies; Antineoplastic Agents, Phytogenic; Chemokine CCL3; Disease Models, Animal; Gene Expression Regulation; Hyperalgesia; Male; Paclitaxel; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, CCR5; Receptors, Purinergic P2X7; RNA, Messenger; Spinal Cord; Time Factors

2014
Colchicine suppresses atrial fibrillation in failing heart.
    International journal of cardiology, 2014, Oct-20, Volume: 176, Issue:3

    Topics: Action Potentials; Animals; Atrial Fibrillation; Blotting, Western; Colchicine; Collagen; Disease Models, Animal; Heart Failure; Ion Channels; Paclitaxel; Polymerase Chain Reaction; Proteins; Rabbits; RNA, Messenger; Signal Transduction

2014
Low-dose paclitaxel improves the therapeutic efficacy of recombinant adenovirus encoding CCL21 chemokine against murine cancer.
    Cancer science, 2014, Volume: 105, Issue:11

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemokine CCL21; Cytokines; Cytotoxicity, Immunologic; Disease Models, Animal; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Melanoma, Experimental; Mice; Neoplasms; Neovascularization, Pathologic; Paclitaxel; T-Cell Antigen Receptor Specificity; T-Lymphocyte Subsets; Tumor Burden

2014
Paclitaxel-loaded PEG-PE-based micellar nanopreparations targeted with tumor-specific landscape phage fusion protein enhance apoptosis and efficiently reduce tumors.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Delivery Systems; Female; Humans; Mice; Micelles; Nanoparticles; Neoplasms; Paclitaxel; Phosphatidylethanolamines; Polyethylene Glycols; Tumor Burden; Xenograft Model Antitumor Assays

2014
The prophylactic effects of a traditional Japanese medicine, goshajinkigan, on paclitaxel-induced peripheral neuropathy and its mechanism of action.
    Molecular pain, 2014, Sep-21, Volume: 10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cells, Cultured; Disease Models, Animal; Drug Administration Schedule; Drugs, Chinese Herbal; Female; Ganglia, Spinal; Gene Expression Profiling; Gene Expression Regulation; Hyperalgesia; Mice; Mice, Transgenic; Mitochondria; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Inbred F344; Sensory Receptor Cells; Time Factors; TRPV Cation Channels

2014
A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.
    Pain, 2014, Volume: 155, Issue:12

    Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Antineoplastic Agents, Phytogenic; Cytokines; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Hyperalgesia; Male; NADP; Neuralgia; Neuroglia; NF-kappa B; Oxidation-Reduction; Paclitaxel; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord; Tumor Necrosis Factor-alpha

2014
Dual-layer surface coating of PLGA-based nanoparticles provides slow-release drug delivery to achieve metronomic therapy in a paclitaxel-resistant murine ovarian cancer model.
    Biomacromolecules, 2014, Nov-10, Volume: 15, Issue:11

    Topics: Administration, Metronomic; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; Mice; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties

2014
Biological effect of orbital atherectomy and adjunctive paclitaxel-coated balloon therapy on vascular healing and drug retention: early experimental insights into the familial hypercholesterolaemic swine model of femoral artery stenosis.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2014, Volume: 10, Issue:8

    Topics: Angioplasty, Balloon; Animals; Antineoplastic Agents, Phytogenic; Atherectomy; Combined Modality Therapy; Constriction, Pathologic; Disease Models, Animal; Femoral Artery; Hyperlipoproteinemia Type II; Paclitaxel; Peripheral Arterial Disease; Swine; Tomography, Optical Coherence; Ultrasonography, Interventional; Wound Healing

2014
"Glowing head" mice: a genetic tool enabling reliable preclinical image-based evaluation of cancers in immunocompetent allografts.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Genes, Reporter; Immunocompromised Host; Kaplan-Meier Estimate; Luciferases; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Paclitaxel; Pituitary Gland; Transplantation, Homologous

2014
Lysophosphatidic acid and its receptors LPA1 and LPA3 mediate paclitaxel-induced neuropathic pain in mice.
    Molecular pain, 2014, Nov-19, Volume: 10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dizocilpine Maleate; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuralgia; Paclitaxel; Pain Measurement; Phospholipases A2; Piperidines; Receptors, Lysophosphatidic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spinal Cord Dorsal Horn; Time Factors

2014
Bu-zhong-yi-qi pill alleviate the chemotherapy-related fatigue in 4 T1 murine breast cancer model.
    BMC complementary and alternative medicine, 2014, Dec-15, Volume: 14

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Disease Models, Animal; Drugs, Chinese Herbal; Fatigue; Female; Humans; Magnoliopsida; Malondialdehyde; Mice; Paclitaxel; Phytotherapy; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2014
Taxol stabilizes gap junctions and reduces ischemic ventricular arrhythmias in rats in vivo.
    Molecular medicine reports, 2015, Volume: 11, Issue:5

    Topics: Action Potentials; Animals; Antineoplastic Agents, Phytogenic; Arrhythmias, Cardiac; Connexin 43; Disease Models, Animal; Electrocardiography; Gap Junctions; Gene Expression Regulation; Myocardial Ischemia; Paclitaxel; Protein Multimerization; Protein Transport; Rats; Tubulin

2015
Investigation of protective role of curcumin against paclitaxel-induced inner ear damage in rats.
    The Laryngoscope, 2015, Volume: 125, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Disease Models, Animal; Ear, Inner; Hearing Loss, Sensorineural; Otoacoustic Emissions, Spontaneous; Paclitaxel; Rats; Rats, Sprague-Dawley; Treatment Outcome

2015
BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers.
    Breast cancer research : BCR, 2015, Jan-13, Volume: 17

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; BRCA1 Protein; Cell Line, Tumor; Cell Movement; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Female; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression; Gene Silencing; Humans; Inhibitor of Apoptosis Proteins; Mice; Neoplastic Stem Cells; Paclitaxel; Peptide Fragments; Phenotype; Proteolysis; RNA Interference; RNA, Small Interfering; Signal Transduction; Survivin; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2015
Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio rerio.
    Pharmaceutical research, 2015, Volume: 32, Issue:6

    Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Endocytosis; Endothelial Cells; Exosomes; Genes, Reporter; Green Fluorescent Proteins; Heterografts; Humans; Neoplasm Transplantation; Paclitaxel; Particle Size; Technology, Pharmaceutical; Time Factors; Tumor Burden; Zebrafish

2015
Multifunctional Polymeric Micelles Co-loaded with Anti-Survivin siRNA and Paclitaxel Overcome Drug Resistance in an Animal Model of Ovarian Cancer.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Down-Regulation; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Mice; Micelles; Microtubules; Ovarian Neoplasms; Paclitaxel; RNA, Messenger; RNA, Small Interfering; Survivin; Xenograft Model Antitumor Assays

2015
MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer.
    Scientific reports, 2015, Feb-17, Volume: 5

    Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Hyaluronan Receptors; Hyaluronic Acid; Nanoparticles; Ovarian Neoplasms; Paclitaxel; RNA Interference; RNA, Small Interfering; Tumor Burden; Xenograft Model Antitumor Assays

2015
A novel neutralizing antibody targeting pregnancy-associated plasma protein-a inhibits ovarian cancer growth and ascites accumulation in patient mouse tumorgrafts.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Antineoplastic Agents; Ascites; Carboplatin; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression; Humans; Immunohistochemistry; Mice; Ovarian Neoplasms; Paclitaxel; Pregnancy-Associated Plasma Protein-A; Prognosis; Xenograft Model Antitumor Assays

2015
Comprehensive analysis of the GABAergic system gene expression profile in the anterior cingulate cortex of mice with Paclitaxel-induced neuropathic pain.
    Gene expression, 2015, Volume: 16, Issue:3

    Topics: Animals; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gyrus Cinguli; Humans; Mice; Neuralgia; Paclitaxel; Receptors, GABA-A; RNA, Messenger; Transcriptome

2015
Gender differences in a mouse model of chemotherapy-induced neuropathic pain.
    Laboratory animals, 2016, Volume: 50, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cisplatin; Disease Models, Animal; Female; Injections, Intraperitoneal; Male; Mice; Neuralgia; Paclitaxel; Sex Factors

2016
Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice.
    Journal of Zhejiang University. Science. B, 2015, Volume: 16, Issue:3

    Topics: Acetanilides; Analgesics; Animals; Benzamides; Capsaicin; Cold Temperature; Disease Models, Animal; Formaldehyde; Hyperalgesia; Isothiocyanates; Male; Mice; Neuralgia; Oximes; Paclitaxel; Pain Measurement; Purines; Thiophenes; Touch; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2015
MiR-1204 sensitizes nasopharyngeal carcinoma cells to paclitaxel both in vitro and in vivo.
    Cancer biology & therapy, 2015, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays

2015
Transplant-mediated enhancement of spinal cord GABAergic inhibition reverses paclitaxel-induced mechanical and heat hypersensitivity.
    Pain, 2015, Volume: 156, Issue:6

    Topics: Activating Transcription Factor 3; Animals; Antineoplastic Agents, Phytogenic; Cell Count; Cell Transplantation; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Paclitaxel; Pain Measurement; Pain Threshold; Spinal Cord; Vesicular Inhibitory Amino Acid Transport Proteins

2015
Valvuloplasty with a paclitaxel-eluting balloon prevents restenosis in an experimental animal model of aortic stenosis.
    The Journal of heart valve disease, 2014, Volume: 23, Issue:4

    Topics: Animals; Aortic Valve Stenosis; Atherosclerosis; Balloon Valvuloplasty; Calcinosis; Calcium; Disease Models, Animal; Paclitaxel; Proliferating Cell Nuclear Antigen; Rabbits; Random Allocation; Recurrence; Ultrasonography; X-Ray Microtomography

2014
Blocking the GABA transporter GAT-1 ameliorates spinal GABAergic disinhibition and neuropathic pain induced by paclitaxel.
    Journal of neurochemistry, 2015, Volume: 133, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Disease Models, Animal; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Neuralgia; Paclitaxel; Rats; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn

2015
An exercise regimen prevents development paclitaxel induced peripheral neuropathy in a mouse model.
    Journal of the peripheral nervous system : JPNS, 2015, Volume: 20, Issue:1

    Topics: Action Potentials; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Male; Mice; Neural Conduction; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Physical Conditioning, Animal

2015
miR-218 targets survivin and regulates resistance to chemotherapeutics in breast cancer.
    Breast cancer research and treatment, 2015, Volume: 151, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Binding Sites; Breast Neoplasms; Caspases; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Mice; MicroRNAs; Paclitaxel; RNA, Messenger; Survivin; Transcriptome; Xenograft Model Antitumor Assays

2015
CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain.
    Molecular pharmacology, 2015, Volume: 88, Issue:1

    Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Male; Mice; Mice, Knockout; Neuralgia; Paclitaxel; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Treatment Outcome

2015
Temporary placement of a paclitaxel or rapamycin-eluting stent is effective to reduce stenting induced inflammatory reaction and scaring in benign cardia stricture models.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2014, Volume: 25 Suppl 1

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cardia; Cicatrix; Constriction, Pathologic; Disease Models, Animal; Dogs; Drug-Eluting Stents; Esophageal Sphincter, Lower; Esophageal Stenosis; Female; Humans; Inflammation; Male; Manometry; Paclitaxel; Random Allocation; Sirolimus; Time Factors

2014
Conventional chemotherapy and oncogenic pathway targeting in ovarian carcinosarcoma using a patient-derived tumorgraft.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinosarcoma; Disease Models, Animal; Female; Gene Expression Profiling; Humans; Maximum Tolerated Dose; Mice; Molecular Targeted Therapy; Ovarian Neoplasms; Paclitaxel; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays

2015
Sensory neuron subpopulation-specific dysregulation of intracellular calcium in a rat model of chemotherapy-induced peripheral neuropathy.
    Neuroscience, 2015, Aug-06, Volume: 300

    Topics: Animals; Antineoplastic Agents, Phytogenic; Calcium; Disease Models, Animal; Ganglia, Spinal; Intracellular Space; Male; Membrane Potentials; Nociceptive Pain; Nociceptors; Paclitaxel; Pain Measurement; Peripheral Nervous System Diseases; Rats, Sprague-Dawley; Skin; Touch

2015
Paclitaxel improves outcome from traumatic brain injury.
    Brain research, 2015, Aug-27, Volume: 1618

    Topics: Animals; Brain Injuries; Disease Models, Animal; Gait Disorders, Neurologic; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Paclitaxel; Treatment Outcome; Tubulin Modulators

2015
Cancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic Platform.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Animals; Apoptosis; Cell Culture Techniques; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Fibroblast Growth Factors; Fibroblasts; Heat-Shock Proteins; Humans; Microfluidics; Neoplasms; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays

2015
Impact of Paclitaxel Dose on Tissue Pharmacokinetics and Vascular Healing: A Comparative Drug-Coated Balloon Study in the Familial Hypercholesterolemic Swine Model of Superficial Femoral In-Stent Restenosis.
    JACC. Cardiovascular interventions, 2015, Volume: 8, Issue:8

    Topics: Animals; Cardiovascular Agents; Coated Materials, Biocompatible; Constriction, Pathologic; Disease Models, Animal; Endovascular Procedures; Femoral Artery; Fibrin; Hyperlipoproteinemia Type II; Metals; Neointima; Paclitaxel; Peripheral Arterial Disease; Radiography; Stents; Swine; Tissue Distribution; Vascular Access Devices; Wound Healing

2015
Bulleyaconitine A depresses neuropathic pain and potentiation at C-fiber synapses in spinal dorsal horn induced by paclitaxel in rats.
    Experimental neurology, 2015, Volume: 273

    Topics: Aconitine; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Hyperalgesia; In Vitro Techniques; Male; Nerve Fibers, Unmyelinated; Neuralgia; Paclitaxel; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Synaptic Potentials; Time Factors

2015
Prevention of chemotherapy-induced peripheral neuropathy by the small-molecule inhibitor pifithrin-μ.
    Pain, 2015, Volume: 156, Issue:11

    Topics: Analgesics; Animals; Antineoplastic Agents, Phytogenic; Cisplatin; Disease Models, Animal; Female; Ganglia, Spinal; Humans; Hyperalgesia; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mitochondria; Paclitaxel; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Sulfonamides; Ubiquitin Thiolesterase; Xenograft Model Antitumor Assays

2015
Bevacizumab-Induced Inhibition of Angiogenesis Promotes a More Homogeneous Intratumoral Distribution of Paclitaxel, Improving the Antitumor Response.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Female; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Mice; Neoplasms; Paclitaxel; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xenograft Model Antitumor Assays

2016
Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis, and possible involvement of the adenosine system.
    Scientific reports, 2015, Nov-03, Volume: 5

    Topics: Adenosine; Alkaloids; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Bignoniaceae; Disease Models, Animal; Edema; Freund's Adjuvant; Hyperalgesia; Interleukin-1beta; Medicine, Chinese Traditional; Mice; Monoterpenes; Motor Activity; Paclitaxel; Pain Measurement; Theobromine; Theophylline; Xanthines

2015
Increased expression of MyD88 and association with paclitaxel resistance in breast cancer.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Knockdown Techniques; Humans; Mice; Middle Aged; Myeloid Differentiation Factor 88; Neoplasm Grading; Neoplasm Staging; NF-kappa B; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays

2016
Biological effect on drug distribution and vascular healing via paclitaxel-coated balloon technology in drug eluting stent restenosis swine model.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016, Volume: 88, Issue:1

    Topics: Animals; Cardiac Catheterization; Cardiac Catheters; Cardiovascular Agents; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Equipment and Supplies; Fibrin; Metals; Neointima; Paclitaxel; Percutaneous Coronary Intervention; Stents; Swine; Tissue Distribution; Tomography, Optical Coherence; Wound Healing

2016
Two-Step Delivery: Exploiting the Partition Coefficient Concept to Increase Intratumoral Paclitaxel Concentrations In vivo Using Responsive Nanoparticles.
    Scientific reports, 2016, Jan-07, Volume: 6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Mesothelioma; Mice; Nanoparticles; Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays

2016
SPARC-Independent Delivery of Nab-Paclitaxel without Depleting Tumor Stroma in Patient-Derived Pancreatic Cancer Xenografts.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:4

    Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Deoxycytidine; Disease Models, Animal; Drug Synergism; Female; Gemcitabine; Humans; Mice; Microcirculation; Osteonectin; Paclitaxel; Pancreatic Neoplasms; Stromal Cells; Tumor Burden; Xenograft Model Antitumor Assays

2016
Linalool-Incorporated Nanoparticles as a Novel Anticancer Agent for Epithelial Ovarian Carcinoma.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:4

    Topics: Acyclic Monoterpenes; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Membrane Potential, Mitochondrial; Mice; Monoterpenes; Nanoparticles; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Reactive Oxygen Species; Tumor Burden; Xenograft Model Antitumor Assays

2016
Low-dose paclitaxel ameliorates renal fibrosis by suppressing transforming growth factor-β1-induced plasminogen activator inhibitor-1 signaling.
    Nephrology (Carlton, Vic.), 2016, Volume: 21, Issue:7

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Matrix Proteins; Fibrosis; Kidney; Kidney Diseases; Male; Mitogen-Activated Protein Kinases; Paclitaxel; Plasminogen Activator Inhibitor 1; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Smad3 Protein; Time Factors; Transforming Growth Factor beta1; Tubulin Modulators; Ureteral Obstruction

2016
Paclitaxel-Loaded Polymersomes for Enhanced Intraperitoneal Chemotherapy.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Carriers; Drug Compounding; Drug Liberation; Drug Stability; Humans; Injections, Intraperitoneal; Mice; Paclitaxel; Peritoneal Neoplasms; Polymers; Tissue Distribution; Xenograft Model Antitumor Assays

2016
Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer.
    Science translational medicine, 2016, Feb-24, Volume: 8, Issue:327

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Humans; Magnetic Resonance Imaging; Mice; Paclitaxel; Survival Analysis; Treatment Outcome

2016
Combination Therapy using Co-encapsulated Resveratrol and Paclitaxel in Liposomes for Drug Resistance Reversal in Breast Cancer Cells in vivo.
    Scientific reports, 2016, Mar-07, Volume: 6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Drug Resistance, Multiple; Female; Liposomes; Mice, Inbred BALB C; Paclitaxel; Resveratrol; Stilbenes; Treatment Outcome; Tubulin Modulators

2016
Paclitaxel Associated With Lipid Nanoparticles as a New Antiscarring Agent in Experimental Glaucoma Surgery.
    Investigative ophthalmology & visual science, 2016, Volume: 57, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cicatrix; Conjunctiva; Disease Models, Animal; Drug Carriers; Follow-Up Studies; Glaucoma; Injections; Intraocular Pressure; Lipids; Male; Nanoparticles; Paclitaxel; Postoperative Complications; Rabbits; Trabeculectomy

2016
Dorsal Root Ganglion Infiltration by Macrophages Contributes to Paclitaxel Chemotherapy-Induced Peripheral Neuropathy.
    The journal of pain, 2016, Volume: 17, Issue:7

    Topics: Anesthetics; Animals; Antibodies; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents, Phytogenic; Bone Density Conservation Agents; Cell Movement; Chemokine CCL2; Clodronic Acid; Disease Models, Animal; Drug Administration Routes; Ganglia, Spinal; GAP-43 Protein; Hyperalgesia; Isoflurane; Lipopolysaccharides; Macrophages; Male; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Spinal Cord; Spleen; Time Factors; Tumor Necrosis Factor-alpha; Ubiquitin Thiolesterase

2016
Therapeutic potential of RQ-00311651, a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain.
    Pain, 2016, Volume: 157, Issue:8

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; Female; HEK293 Cells; Humans; Hyperalgesia; Male; Mice; Neuralgia; Nociception; Paclitaxel; Rats; Rats, Wistar; Visceral Pain

2016
Evaluation of expansile nanoparticle tumor localization and efficacy in a cancer stem cell-derived model of pancreatic peritoneal carcinomatosis.
    Nanomedicine (London, England), 2016, Volume: 11, Issue:9

    Topics: Animals; Carcinoma; Disease Models, Animal; Drug Delivery Systems; Humans; Nanoparticles; Neoplastic Stem Cells; Paclitaxel; Pancreatic Neoplasms; Peritoneum; Rats; Rhodamines; Xenograft Model Antitumor Assays

2016
Pharmacokinetic Evaluation of Two Paclitaxel-Coated Balloons with Different Drug Load in a Short-Term Porcine Study.
    Cardiovascular and interventional radiology, 2016, Volume: 39, Issue:8

    Topics: Angioplasty, Balloon; Animals; Coated Materials, Biocompatible; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperplasia; Iliac Artery; Male; Paclitaxel; Sus scrofa; Swine; Tubulin Modulators

2016
Identification of fluocinolone acetonide to prevent paclitaxel-induced peripheral neuropathy.
    Journal of the peripheral nervous system : JPNS, 2016, Volume: 21, Issue:3

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Axons; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fluocinolone Acetonide; Ganglia, Spinal; Mice; Nerve Fibers; Neurons; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley

2016
Osimertinib (AZD9291) Enhanced the Efficacy of Chemotherapeutic Agents in ABCB1- and ABCG2-Overexpressing Cells In Vitro, In Vivo, and Ex Vivo.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:8

    Topics: Acrylamides; Aniline Compounds; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Cell Membrane; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Flow Cytometry; Gene Expression; Humans; Mice; Paclitaxel; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Xenograft Model Antitumor Assays

2016
Cyclin-Dependent Kinase 11 (CDK11) Is Required for Ovarian Cancer Cell Growth In Vitro and In Vivo, and Its Inhibition Causes Apoptosis and Sensitizes Cells to Paclitaxel.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinases; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mice; Ovarian Neoplasms; Paclitaxel; RNA Interference; RNA, Small Interfering; Xenograft Model Antitumor Assays

2016
mir-500-Mediated GAD67 Downregulation Contributes to Neuropathic Pain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 06-08, Volume: 36, Issue:23

    Topics: Action Potentials; Animals; Antagomirs; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Down-Regulation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyperalgesia; Inhibitory Postsynaptic Potentials; Male; MicroRNAs; Neuralgia; Paclitaxel; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Transcription Activator-Like Effector Nucleases

2016
Low doses of paclitaxel enhance liver metastasis of breast cancer cells in the mouse model.
    The FEBS journal, 2016, Volume: 283, Issue:15

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Epithelial-Mesenchymal Transition; Estrogens; Female; Gene Expression; Gene Expression Profiling; Humans; Inflammation Mediators; Liver; Liver Neoplasms; Mice; Neoplasm Invasiveness; NF-kappa B; Paclitaxel

2016
Oxidative stress in the development, maintenance and resolution of paclitaxel-induced painful neuropathy.
    Neuroscience, 2016, 10-01, Volume: 333

    Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; Cells, Cultured; Disease Models, Animal; Disease Progression; Ganglia, Spinal; Hyperalgesia; Lumbar Vertebrae; Male; Microglia; Neurons; Oxidative Stress; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats, Sprague-Dawley; Reactive Oxygen Species; Spinal Cord

2016
Paclitaxel causes degeneration of both central and peripheral axon branches of dorsal root ganglia in mice.
    BMC neuroscience, 2016, 07-11, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents; Axons; Disease Models, Animal; Female; Ganglia, Spinal; Male; Mice, Inbred C57BL; Microscopy, Electron; Nerve Degeneration; Paclitaxel; Peripheral Nervous System Diseases; Sciatic Nerve; Spinal Cord

2016
CHK1 Inhibition Radiosensitizes Head and Neck Cancers to Paclitaxel-Based Chemoradiotherapy.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:9

    Topics: Aminopyridines; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 1; Chemoradiotherapy; Combined Modality Therapy; Disease Models, Animal; Female; Head and Neck Neoplasms; Humans; Mice; Mitosis; Neoplastic Stem Cells; Paclitaxel; Protein Kinase Inhibitors; Pyrimidines; Radiation Tolerance; Radiation-Sensitizing Agents; Radiation, Ionizing; Xenograft Model Antitumor Assays

2016
Rescuing Impaired Re-endothelialization of Drug-Eluting Stents Using the Hepatocyte Growth Factor.
    Annals of vascular surgery, 2016, Volume: 36

    Topics: Angioplasty, Balloon; Animals; Apoptosis; Cardiovascular Agents; Carotid Arteries; Carotid Artery Diseases; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Eluting Stents; Endothelial Progenitor Cells; Hepatocyte Growth Factor; Hypercholesterolemia; Injections, Subcutaneous; Male; Neointima; Paclitaxel; Rabbits; Re-Epithelialization; Time Factors

2016
Ultrasound-Mediated Microbubble Destruction (UMMD) Facilitates the Delivery of CA19-9 Targeted and Paclitaxel Loaded mPEG-PLGA-PLL Nanoparticles in Pancreatic Cancer.
    Theranostics, 2016, Volume: 6, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; CA-19-9 Antigen; Cell Survival; Disease Models, Animal; Drug Carriers; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Microbubbles; Nanoparticles; Paclitaxel; Pancreatic Neoplasms; Polyesters; Polyethylene Glycols; Survival Analysis; Treatment Outcome; Tumor Cells, Cultured; Ultrasonography

2016
Involvement of high mobility group box 1 in the development and maintenance of chemotherapy-induced peripheral neuropathy in rats.
    Toxicology, 2016, 07-15, Volume: 365

    Topics: Animals; Antibodies, Neutralizing; Antineoplastic Agents; Disease Models, Animal; Ganglia, Spinal; HMGB1 Protein; Hyperalgesia; Male; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Recombinant Proteins; Sciatic Nerve; Thrombomodulin; Toll-Like Receptor 4; Vincristine

2016
Combination of Paclitaxel and MG1 oncolytic virus as a successful strategy for breast cancer treatment.
    Breast cancer research : BCR, 2016, 08-08, Volume: 18, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Disease Models, Animal; Female; Humans; Interferon-beta; Mice; Oncolytic Virotherapy; Oncolytic Viruses; Paclitaxel; Tumor Burden; Virus Replication; Xenograft Model Antitumor Assays

2016
Alternating electric fields (TTFields) in combination with paclitaxel are therapeutically effective against ovarian cancer cells in vitro and in vivo.
    International journal of cancer, 2016, Dec-15, Volume: 139, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Disease Models, Animal; Female; Humans; Mice; Ovarian Neoplasms; Paclitaxel; Treatment Outcome; Xenograft Model Antitumor Assays

2016
Knockdown of Hypoxia-Inducible Factor 1α Improved the Efficacy of Low-Dose Metronomic Chemotherapy of Paclitaxel in Human Colon Cancer Xenografts.
    Technology in cancer research & treatment, 2017, Volume: 16, Issue:5

    Topics: Administration, Metronomic; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Neovascularization, Pathologic; Paclitaxel; RNA Interference; RNA, Small Interfering; Xenograft Model Antitumor Assays

2017
Styrene maleic acid-encapsulated paclitaxel micelles: antitumor activity and toxicity studies following oral administration in a murine orthotopic colon cancer model.
    International journal of nanomedicine, 2016, Volume: 11

    Topics: Administration, Oral; Alanine Transaminase; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Body Weight; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Drug Liberation; Female; Humans; Maleates; Maximum Tolerated Dose; Mice, Inbred BALB C; Micelles; Microvessels; Neovascularization, Physiologic; Paclitaxel; Polystyrenes; Static Electricity; Toxicity Tests

2016
Avian axons undergo Wallerian degeneration after injury and stress.
    Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2016, Volume: 202, Issue:11

    Topics: Analysis of Variance; Animals; Axons; Axotomy; Calcium; Cells, Cultured; Disease Models, Animal; Finches; Microscopy, Confocal; Microscopy, Fluorescence; NAD; Nerve Degeneration; Paclitaxel; Pressure; Retinal Ganglion Cells; Stress, Physiological; Vincristine; Wallerian Degeneration

2016
Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway.
    Oncotarget, 2016, Nov-08, Volume: 7, Issue:45

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Diterpenes, Kaurane; Drug Synergism; Humans; Male; Membrane Potential, Mitochondrial; Mice; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Reactive Oxygen Species; Signal Transduction; Stomach Neoplasms; Xenograft Model Antitumor Assays

2016
A New Concept of Enhancing Immuno-Chemotherapeutic Effects Against B16F10 Tumor
    Theranostics, 2016, Volume: 6, Issue:12

    Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Carriers; Galactosylceramides; Immunotherapy; Liposomes; Melanoma; Mice, Inbred C57BL; Nanostructures; Paclitaxel; Treatment Outcome

2016
miR-186 regulates chemo-sensitivity to paclitaxel via targeting MAPT in non-small cell lung cancer (NSCLC).
    Molecular bioSystems, 2016, 10-18, Volume: 12, Issue:11

    Topics: 3' Untranslated Regions; Adult; Aged; Animals; Apoptosis; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Lung Neoplasms; Mice; MicroRNAs; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Paclitaxel; Prognosis; RNA Interference; tau Proteins; Tumor Burden; Xenograft Model Antitumor Assays

2016
Biological effect on restenosis and vascular healing of encapsulated paclitaxel nanocrystals delivered via coated balloon technology in the familial hypercholesterolaemic swine model of in-stent restenosis.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2016, Oct-20, Volume: 12, Issue:9

    Topics: Angiography; Angioplasty, Balloon, Coronary; Animals; Antineoplastic Agents; Disease Models, Animal; Femoral Artery; Graft Occlusion, Vascular; Hyperlipoproteinemia Type II; Iliac Artery; Metals; Nanoparticles; Neointima; Paclitaxel; Peripheral Vascular Diseases; Stents; Sus scrofa; Swine; Tomography, Optical Coherence; Wound Healing

2016
MitoVitE, a mitochondria-targeted antioxidant, limits paclitaxel-induced oxidative stress and mitochondrial damage in vitro, and paclitaxel-induced mechanical hypersensitivity in a rat pain model.
    British journal of anaesthesia, 2016, Volume: 117, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Disease Models, Animal; Hyperalgesia; In Vitro Techniques; Male; Mitochondria; Neuralgia; Organophosphorus Compounds; Oxidative Stress; Paclitaxel; Rats; Rats, Sprague-Dawley; Ubiquinone

2016
MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; MAP Kinase Signaling System; Mice; Microfilament Proteins; Microtubules; Neoplasm Metastasis; Paclitaxel; Protein Isoforms; Triple Negative Breast Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2017
Paclitaxel Drug-eluting Tracheal Stent Could Reduce Granulation Tissue Formation in a Canine Model.
    Chinese medical journal, 2016, 11-20, Volume: 129, Issue:22

    Topics: Animals; Bronchoscopy; Disease Models, Animal; Dogs; Drug-Eluting Stents; Granulation Tissue; Microscopy, Electron, Scanning; Paclitaxel; Trachea; Tracheal Stenosis

2016
Paclitaxel inhibits post-traumatic recurrent laryngeal nerve regeneration into the posterior cricoarytenoid muscle in a canine model.
    The Laryngoscope, 2017, Volume: 127, Issue:3

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Injections, Intramuscular; Laryngeal Muscles; Nerve Regeneration; Paclitaxel; Random Allocation; Recurrent Laryngeal Nerve Injuries; Reference Values; Vincristine; Vocal Cord Paralysis

2017
Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3.2) in paclitaxel-induced peripheral neuropathy.
    Pain, 2017, Volume: 158, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Azabicyclo Compounds; Benzamides; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Humans; Hyperalgesia; Male; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Spinal Cord; Sulfonamides; Toll-Like Receptor 4

2017
Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models.
    Oncotarget, 2017, Jan-10, Volume: 8, Issue:2

    Topics: Acetylation; Animals; Antineoplastic Agents; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Synergism; Female; Histone Deacetylase Inhibitors; Humans; Paclitaxel; Spindle Apparatus; Tubulin; Xenograft Model Antitumor Assays

2017
Heterogeneity of paclitaxel distribution in different tumor models assessed by MALDI mass spectrometry imaging.
    Scientific reports, 2016, 12-21, Volume: 6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Female; Heterografts; Humans; Image Processing, Computer-Assisted; Male; Mice; Neoplasm Transplantation; Neoplasms; Paclitaxel; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2016
Ultrasound-mediated destruction of oxygen and paclitaxel loaded dual-targeting microbubbles for intraperitoneal treatment of ovarian cancer xenografts.
    Cancer letters, 2017, 04-10, Volume: 391

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Humans; Infusions, Parenteral; Mice; Microbubbles; Ovarian Neoplasms; Oxygen; Paclitaxel; Ultrasonics; Xenograft Model Antitumor Assays

2017
Patient-Derived Xenograft Models of Epithelial Ovarian Cancer for Preclinical Studies.
    Cancer research and treatment, 2017, Volume: 49, Issue:4

    Topics: Adult; Animals; Antineoplastic Agents; Biomarkers, Tumor; Biopsy; Carboplatin; Carcinoma, Ovarian Epithelial; Disease Models, Animal; Drug Evaluation, Preclinical; ErbB Receptors; Female; Genomic Instability; Heterografts; Humans; Mice; Middle Aged; Molecular Targeted Therapy; Neoplasm Grading; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Translational Research, Biomedical; Xenograft Model Antitumor Assays

2017
Epigenetic upregulation of CXCL12 expression mediates antitubulin chemotherapeutics-induced neuropathic pain.
    Pain, 2017, Volume: 158, Issue:4

    Topics: Animals; Antibodies; Chemokine CXCL12; Disease Models, Animal; Evoked Potentials; Excitatory Postsynaptic Potentials; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuralgia; Paclitaxel; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; RNA, Small Interfering; Spinal Cord; STAT3 Transcription Factor; Time Factors; Tubulin; Up-Regulation; Vincristine

2017
MiR-1307 promotes ovarian cancer cell chemoresistance by targeting the ING5 expression.
    Journal of ovarian research, 2017, Jan-11, Volume: 10, Issue:1

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Mice; MicroRNAs; Ovarian Neoplasms; Paclitaxel; RNA Interference; Transcription Factors; Transfection; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2017
Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer.
    Cancer immunology research, 2017, Volume: 5, Issue:3

    Topics: Albumins; Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Macrophage Activation; Macrophages; Paclitaxel; Pancreatic Neoplasms; Pinocytosis; Toll-Like Receptor 4; Xenograft Model Antitumor Assays

2017
Effects of Taxol on Regeneration in a Rat Sciatic Nerve Transection Model.
    Scientific reports, 2017, 02-09, Volume: 7

    Topics: Adrenergic Neurons; Animals; Axons; Calcitonin Gene-Related Peptide; Disease Models, Animal; Electrophysiological Phenomena; Gene Expression Regulation; Hot Temperature; Hyperalgesia; Macrophages; Motor Activity; Nerve Regeneration; Paclitaxel; Rats, Sprague-Dawley; RNA, Messenger; Sciatic Nerve; Silicone Elastomers; Spinal Cord Dorsal Horn; Stilbamidines

2017
PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.
    Breast cancer research and treatment, 2017, Volume: 162, Issue:3

    Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Centromere; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; DNA Copy Number Variations; Drug Resistance, Neoplasm; Female; Gene Amplification; Gene Editing; Gene Knockout Techniques; Genomic Instability; Genotype; Humans; Mice; Mutation; Paclitaxel; Phenotype; Tumor Suppressor Protein p53

2017
Anti-proliferative effect of Jesridonin on paclitaxel-resistant EC109 human esophageal carcinoma cells.
    International journal of molecular medicine, 2017, Volume: 39, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Mice; Neoplastic Stem Cells; Paclitaxel; Xenograft Model Antitumor Assays

2017
A novel intraperitoneal metastatic xenograft mouse model for survival outcome assessment of esophageal adenocarcinoma.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; Esophageal Neoplasms; Heterografts; Mice; Neoplasm Transplantation; Paclitaxel; Peritoneal Neoplasms

2017
The effect of paclitaxel-eluting covered metal stents versus covered metal stents in a rabbit esophageal squamous carcinoma model.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug-Eluting Stents; Esophageal Neoplasms; Female; Male; Paclitaxel; Rabbits

2017
Radionuclide I-131 Labeled Albumin-Paclitaxel Nanoparticles for Synergistic Combined Chemo-radioisotope Therapy of Cancer.
    Theranostics, 2017, Volume: 7, Issue:3

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Disease Models, Animal; Iodine Radioisotopes; Mice; Mice, Nude; Nanoparticles; Paclitaxel; Serum Albumin; Serum Albumin, Human; Treatment Outcome

2017
The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:6

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression; Humans; Male; Mice; Models, Molecular; Molecular Conformation; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Piperidines; Protein Binding; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Tumor Burden; Xenograft Model Antitumor Assays

2017
Regorafenib overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter in colorectal cancer: In vitro and in vivo study.
    Cancer letters, 2017, 06-28, Volume: 396

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Mice; Paclitaxel; Phenylurea Compounds; Pyridines; Xenograft Model Antitumor Assays

2017
Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model.
    Breast cancer research and treatment, 2009, Volume: 115, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Hyaluronan Receptors; Mice; Mice, Nude; Neoplastic Stem Cells; NF-kappa B; Oxyquinoline; Paclitaxel; Xenograft Model Antitumor Assays

2009
Implantation of paclitaxel-eluting stent impairs the vascular compliance of arteries in porcine coronary stenting model.
    Atherosclerosis, 2009, Volume: 202, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Female; Inflammation; Male; Metals; Nitroglycerin; Paclitaxel; Swine; Vasodilation

2009
Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2.
    British journal of pharmacology, 2008, Volume: 155, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Peptides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2008
MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models.
    British journal of pharmacology, 2008, Volume: 155, Issue:7

    Topics: Analgesics; Animals; Benzofurans; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Ligation; Motor Activity; Neuralgia; Paclitaxel; Pain Measurement; Piperidines; Radioligand Assay; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Species Specificity; Spinal Nerves

2008
Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Oct-15, Volume: 14, Issue:20

    Topics: Adenocarcinoma; Adult; Aged; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Carboplatin; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cetuximab; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Etoposide; Female; Gemcitabine; Gene Expression Profiling; Genes, ras; Humans; Immunoblotting; Lung Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Middle Aged; Mutation; Oligonucleotide Array Sequence Analysis; Paclitaxel; Polymerase Chain Reaction; Prognosis; Protein Kinase Inhibitors; Quinazolines; Radiation-Sensitizing Agents; Small Cell Lung Carcinoma; Tumor Suppressor Protein p53; Vinblastine; Vinorelbine; Xenograft Model Antitumor Assays

2008
In situ blood-brain barrier permeability of a C-10 paclitaxel carbamate.
    Bioorganic & medicinal chemistry letters, 2008, Dec-01, Volume: 18, Issue:23

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamates; Central Nervous System; Disease Models, Animal; Mice; Molecular Structure; Neurodegenerative Diseases; Paclitaxel; Permeability; Structure-Activity Relationship

2008
Efficacy assessment of sustained intraperitoneal paclitaxel therapy in a murine model of ovarian cancer using bioluminescent imaging.
    British journal of cancer, 2008, Dec-16, Volume: 99, Issue:12

    Topics: Animals; Body Weight; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Disease Progression; Female; Humans; Injections, Intraperitoneal; Luminescent Measurements; Mice; Mice, SCID; Ovarian Neoplasms; Paclitaxel; Survival Rate; Xenograft Model Antitumor Assays

2008
IL-13 cytotoxin has potent antitumor activity and synergizes with paclitaxel in a mouse model of oral squamous cell carcinoma.
    International journal of cancer, 2009, Mar-15, Volume: 124, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Exotoxins; Humans; Interleukin-13; Mice; Mouth Neoplasms; Paclitaxel; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tongue Neoplasms; Transplantation, Heterologous

2009
Effect of the chronic combined administration of cisplatin and paclitaxel in a rat model of peripheral neurotoxicity.
    European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cisplatin; Disease Models, Animal; Drug Administration Schedule; Female; Ganglia, Spinal; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Weight Loss

2009
Histologic influence of paclitaxel-eluting covered metallic stents in a canine biliary model.
    Gastrointestinal endoscopy, 2009, Volume: 69, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Coated Materials, Biocompatible; Common Bile Duct; Disease Models, Animal; Dogs; Drug-Eluting Stents; Epithelium; Equipment Safety; Hyperplasia; Male; Mucous Membrane; Paclitaxel; Polyurethanes

2009
Intimal proliferation and restenosis in paclitaxel-eluting stents with aminoparylene as carrier substance in swines.
    The Journal of invasive cardiology, 2009, Volume: 21, Issue:3

    Topics: Animals; Cell Proliferation; Chromium Alloys; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug Hypersensitivity; Drug-Eluting Stents; Incidence; Metals; Paclitaxel; Polymers; Stents; Swine; Tunica Intima; Xylenes

2009
Comparison of two different paclitaxel-coated balloon catheters in the porcine coronary restenosis model.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2009, Volume: 98, Issue:5

    Topics: Animals; Catheterization; Coated Materials, Biocompatible; Coronary Restenosis; Disease Models, Animal; Drug-Eluting Stents; Graft Occlusion, Vascular; Humans; Paclitaxel; Swine; Tubulin Modulators

2009
Comparative healing response after sirolimus- and paclitaxel-eluting stent implantation in a pig model of restenosis.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, May-01, Volume: 73, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Animals; Cardiovascular Agents; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Inflammation; Paclitaxel; Platelet Endothelial Cell Adhesion Molecule-1; Platelet-Derived Growth Factor; Sirolimus; Swine; Swine, Miniature; Time Factors; Vascular Endothelial Growth Factor A; Wound Healing

2009
Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma.
    Journal of translational medicine, 2009, Mar-26, Volume: 7

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; Female; Gemcitabine; Humans; Interphase; Ligands; Mice; Mice, Inbred C57BL; Paclitaxel; Pancreatic Neoplasms; Receptors, sigma; Survival Analysis

2009
Prevention of paclitaxel and cisplatin induced ovarian damage in rats by a gonadotropin-releasing hormone agonist.
    Fertility and sterility, 2010, Mar-15, Volume: 93, Issue:5

    Topics: Animals; Anovulation; Antineoplastic Agents; Cisplatin; Disease Models, Animal; Drug Administration Schedule; Female; Fertility; Fertility Agents, Female; Gonadotropin-Releasing Hormone; Infertility, Female; Injections, Subcutaneous; Leuprolide; Ovarian Follicle; Paclitaxel; Rats; Rats, Wistar

2010
Paclitaxel: friend or foe for systemic lupus erythematosus?
    Southern medical journal, 2009, Volume: 102, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Humans; Lupus Erythematosus, Systemic; Mice; Mice, Inbred NZB; Paclitaxel

2009
Evaluation of a novel slow-release paclitaxel-eluting stent with a bioabsorbable polymeric surface coating.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Coated Materials, Biocompatible; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Drug-Eluting Stents; Lactic Acid; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prosthesis Design; Swine

2008
Sensitization of ABCB1 overexpressing cells to chemotherapeutic agents by FG020326 via binding to ABCB1 and inhibiting its function.
    Biochemical pharmacology, 2009, Aug-15, Volume: 78, Issue:4

    Topics: Acrylates; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Imidazoles; KB Cells; Mice; Mice, Nude; Multidrug Resistance-Associated Proteins; Paclitaxel; Vincristine; Xenograft Model Antitumor Assays

2009
Effect of drug-eluting metal stents in benign esophageal stricture: an in vivo animal study.
    Endoscopy, 2009, Volume: 41, Issue:5

    Topics: Alloys; Animals; Antineoplastic Agents, Phytogenic; Cell Division; Disease Models, Animal; Dogs; Drug-Eluting Stents; Epithelium; Equipment Design; Esophageal Stenosis; Esophagoscopy; Esophagus; Focal Adhesions; Granulation Tissue; Mucous Membrane; Paclitaxel

2009
Endothelium-dependent vasomotor dysfunction in pig coronary arteries with Paclitaxel-eluting stents is associated with inflammation and oxidative stress.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Coronary Artery Disease; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Endothelium, Vascular; Inflammation; Oxidative Stress; Paclitaxel; Swine

2009
Comparison of inflammatory response after implantation of sirolimus- and paclitaxel-eluting stents in porcine coronary arteries.
    Circulation, 2009, Jul-14, Volume: 120, Issue:2

    Topics: Animals; Arteritis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Eosinophils; Female; Fibrin; Fibrosis; Granuloma, Foreign-Body; Paclitaxel; Sirolimus; Swine; Tunica Intima

2009
Adjuvant treatment with locally delivered OncoGel delays the onset of paresis after surgical resection of experimental spinal column metastasis.
    Neurosurgery, 2009, Volume: 65, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Disease Models, Animal; Drug Delivery Systems; Female; Hindlimb; Neoplasm Transplantation; Neurologic Examination; Paclitaxel; Radiotherapy, Adjuvant; Rats; Rats, Inbred F344; Spinal Neoplasms; Statistics, Nonparametric; Time Factors

2009
Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models.
    European journal of pharmacology, 2009, Sep-01, Volume: 617, Issue:1-3

    Topics: Analgesics; Animals; Botulinum Toxins, Type A; Carrageenan; Dantrolene; Disease Models, Animal; Edema; Hyperalgesia; Inflammation; Injections; Male; Motor Activity; Paclitaxel; Polyneuropathies; Rats; Rats, Sprague-Dawley

2009
Aerosol delivery of liposomal formulated paclitaxel and vitamin E analog reduces murine mammary tumor burden and metastases.
    Experimental biology and medicine (Maywood, N.J.), 2009, Volume: 234, Issue:10

    Topics: Administration, Inhalation; Aerosols; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Immunohistochemistry; Liposomes; Lymph Nodes; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neovascularization, Pathologic; Paclitaxel; Tumor Burden; Vitamin E

2009
Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane.
    Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:5

    Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Lung Neoplasms; Melanoma, Experimental; Mice; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Proteins; Transplantation, Heterologous; Treatment Outcome

2010
PLGA nanoparticles stabilized with cationic surfactant: safety studies and application in oral delivery of paclitaxel to treat chemical-induced breast cancer in rat.
    Pharmaceutical research, 2009, Volume: 26, Issue:11

    Topics: Administration, Oral; Animals; Breast Neoplasms; Caco-2 Cells; Cations; Cells, Cultured; Disease Models, Animal; Drug Carriers; Drug Stability; Female; Humans; Nanocapsules; Paclitaxel; Particle Size; Polyglactin 910; Rats; Rats, Sprague-Dawley; Surface-Active Agents

2009
Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer.
    The Journal of clinical investigation, 2009, Volume: 119, Issue:10

    Topics: Afatinib; Amphiregulin; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cetuximab; Disease Models, Animal; Drug Resistance, Neoplasm; EGF Family of Proteins; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Profiling; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Male; Mice; Mice, Nude; Mice, Transgenic; Mutation; Neoplasm Transplantation; Paclitaxel; Protein Kinase Inhibitors; Quinazolines; Transplantation, Heterologous; Tumor Cells, Cultured

2009
Identification and characterization of cancer stem-like cells from primary carcinoma of the cervix uteri.
    Oncology reports, 2009, Volume: 22, Issue:5

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Hyaluronan Receptors; Imines; Immunoenzyme Techniques; Mice; Mice, Nude; Neoplastic Stem Cells; Paclitaxel; Spheroids, Cellular; Thiazines; Uterine Cervical Neoplasms

2009
Combined anti-angiogenic therapy against VEGF and integrin alphaVbeta3 in an orthotopic model of ovarian cancer.
    Cancer biology & therapy, 2009, Volume: 8, Issue:23

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis; Bevacizumab; Blotting, Western; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; Immunoenzyme Techniques; Immunoprecipitation; Integrin alphaVbeta3; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2009
Olesoxime (cholest-4-en-3-one, oxime): analgesic and neuroprotective effects in a rat model of painful peripheral neuropathy produced by the chemotherapeutic agent, paclitaxel.
    Pain, 2009, Dec-15, Volume: 147, Issue:1-3

    Topics: Analysis of Variance; Animals; Area Under Curve; Cholestenones; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Evoked Potentials; Hyperalgesia; Male; Nerve Fibers; Neuralgia; Neuroprotective Agents; Paclitaxel; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Ubiquitin Thiolesterase

2009
Differential pharmacodynamic effects of paclitaxel formulations in an intracranial rat brain tumor model.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Brain Neoplasms; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Screening Assays, Antitumor; Glycerol; Liposomes; Male; Maximum Tolerated Dose; Models, Theoretical; Neutropenia; Paclitaxel; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains; Tumor Burden

2010
Lesion complexity determines arterial drug distribution after local drug delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Mar-19, Volume: 142, Issue:3

    Topics: Animals; Aorta, Abdominal; Atherosclerosis; Cholesterol; Disease Models, Animal; Drug Delivery Systems; Drug-Eluting Stents; Everolimus; Humans; Male; Paclitaxel; Protein Binding; Rabbits; Sirolimus; Tissue Distribution; Tunica Intima

2010
Inhibition of human gastric carcinoma cell growth in vitro and in vivo by cladosporol isolated from the paclitaxel-producing strain Alternaria alternata var. monosporus.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:12

    Topics: Alternaria; Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthalenes; Neoplasms; Paclitaxel; Plant Bark; Stomach Neoplasms; Taxus; Transplantation, Heterologous

2009
(-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma.
    Breast cancer research : BCR, 2010, Volume: 12, Issue:1

    Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Female; Heat-Shock Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Paclitaxel

2010
Letter by Virmani et al regarding article, "Drug-eluting stents in animals and patients: where do we stand today?".
    Circulation, 2010, Mar-23, Volume: 121, Issue:11

    Topics: Animals; Disease Models, Animal; Drug-Eluting Stents; Humans; Paclitaxel; Risk Factors; Sirolimus; Swine; Thrombosis

2010
Down-modulation of survivin expression and inhibition of tumor growth in vivo by EZN-3042, a locked nucleic acid antisense oligonucleotide.
    Nucleosides, nucleotides & nucleic acids, 2010, Volume: 29, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Liver Regeneration; Lung Neoplasms; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Oligonucleotides; Oligonucleotides, Antisense; Paclitaxel; RNA, Messenger; Survivin; Treatment Outcome; Xenograft Model Antitumor Assays

2010
Novel biodegradable polymer-coated, paclitaxel-eluting stent inhibits neointimal formation in porcine coronary arteries.
    Kardiologia polska, 2010, Volume: 68, Issue:5

    Topics: Absorbable Implants; Animals; Coated Materials, Biocompatible; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Eluting Stents; Hyperplasia; Materials Testing; Paclitaxel; Polyesters; Swine; Tunica Intima

2010
Targeted molecular therapy of head and neck squamous cell carcinoma with the tyrosine kinase inhibitor vandetanib in a mouse model.
    Head & neck, 2011, Volume: 33, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Disease Models, Animal; ErbB Receptors; Flow Cytometry; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Nude; Molecular Targeted Therapy; Paclitaxel; Piperidines; Protein-Tyrosine Kinases; Quinazolines; Random Allocation; Sensitivity and Specificity; Survival Rate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

2011
Chemotherapy induces macrophage chemoattractant protein-1 production in ovarian cancer.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2010, Volume: 20, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cell Line, Tumor; Chemokine CCL2; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Macrophages; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Signal Transduction; Up-Regulation

2010
Characterization and preparation of core-shell type nanoparticle for encapsulation of anticancer drug.
    Colloids and surfaces. B, Biointerfaces, 2010, Dec-01, Volume: 81, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Chitosan; Cholesterol; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Design; Drug Screening Assays, Antitumor; Female; Mice; Mice, Inbred BALB C; Molecular Conformation; Molecular Weight; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Particle Size; Polyethylene Glycols; Solubility; Surface Properties

2010
Radiation-guided drug delivery to mouse models of lung cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Oct-15, Volume: 16, Issue:20

    Topics: Albumins; Amino Acid Sequence; Animals; Biological Availability; Carcinoma, Large Cell; Carcinoma, Lewis Lung; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Guinea Pigs; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Molecular Sequence Data; Paclitaxel; Peptides; Rabbits; Tissue Distribution; Xenograft Model Antitumor Assays

2010
Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Dec-01, Volume: 16, Issue:23

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Female; Humans; Mice; Mice, Nude; Paclitaxel; Permeability; Treatment Outcome; Xenograft Model Antitumor Assays

2010
Neurophysiological and neuropathological characterization of new murine models of chemotherapy-induced chronic peripheral neuropathies.
    Experimental neurology, 2010, Volume: 226, Issue:2

    Topics: Analysis of Variance; Animals; Antineoplastic Agents; Body Weight; Boronic Acids; Bortezomib; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ganglia, Spinal; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Nerve Fibers, Myelinated; Neural Conduction; Paclitaxel; Peripheral Nervous System Diseases; Pyrazines; Sciatic Nerve

2010
Anti-tumor effects of adenovirus containing human growth hormone sequences in a mouse model of human ovarian cancer.
    Endocrine, 2010, Volume: 37, Issue:3

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Base Sequence; Carboplatin; Combined Modality Therapy; Disease Models, Animal; Female; Human Growth Hormone; Humans; Injections, Intraperitoneal; Mice; Mice, SCID; Ovarian Neoplasms; Paclitaxel

2010
In vivo activity of novel anti-ErbB2 antibody chA21 alone and with Paclitaxel or Trastuzumab in breast and ovarian cancer xenograft models.
    Cancer immunology, immunotherapy : CII, 2011, Volume: 60, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Female; Humans; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Ovarian Neoplasms; Paclitaxel; Receptor, ErbB-2; Signal Transduction; Trastuzumab; Xenograft Model Antitumor Assays

2011
Intraepidermal nerve fiber loss corresponds to the development of taxol-induced hyperalgesia and can be prevented by treatment with minocycline.
    Pain, 2011, Volume: 152, Issue:2

    Topics: Animals; Disease Models, Animal; Epidermis; Hyperalgesia; Male; Minocycline; Nerve Fibers; Neurotoxins; Paclitaxel; Rats; Rats, Sprague-Dawley

2011
Dose response to Paclitaxel-coated balloon catheters in the porcine coronary overstretch and stent implantation model.
    Investigative radiology, 2011, Volume: 46, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Animals; Catheters; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Male; Paclitaxel; Swine; Vascular Diseases

2011
Comparative assessment of drug-eluting balloons in an advanced porcine model of coronary restenosis.
    Thrombosis and haemostasis, 2011, Volume: 105, Issue:5

    Topics: Angioplasty, Balloon; Animals; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Endothelium, Vascular; Fibrin; Humans; Neointima; Paclitaxel; Swine; Wound Healing

2011
Evaluation of combined bevacizumab and intraperitoneal carboplatin or paclitaxel therapy in a mouse model of ovarian cancer.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:4

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biological Availability; Carboplatin; Disease Models, Animal; Female; Injections, Intraperitoneal; Injections, Intravenous; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Peritoneal Neoplasms; Survival Rate; Xenograft Model Antitumor Assays

2011
Genexol inhibits primary tumour growth and metastases in gemcitabine-resistant pancreatic ductal adenocarcinoma.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2011, Volume: 13, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; Gemcitabine; Humans; Male; Mice; Mice, Nude; Paclitaxel; Pancreatic Neoplasms

2011
Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer.
    Oncogene, 2011, Jul-14, Volume: 30, Issue:28

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Membrane; Cell Proliferation; Curcumin; Disease Models, Animal; DNA Fragmentation; Down-Regulation; Drug Synergism; Enzyme Activation; Female; HeLa Cells; Humans; Liposomes; MAP Kinase Signaling System; Methylcholanthrene; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Paclitaxel; Poly Adenosine Diphosphate Ribose; Proto-Oncogene Proteins c-akt; Transcription Factor AP-1; Transcription, Genetic; Tumor Burden; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2011
Taxol facilitates axon regeneration in the mature CNS.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Feb-16, Volume: 31, Issue:7

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Astrocytes; Axons; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glial Fibrillary Acidic Protein; Growth Cones; Macrophages; Myelin Sheath; Nerve Growth Factor; Nerve Regeneration; Optic Nerve Injuries; Paclitaxel; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; rhoA GTP-Binding Protein; Time Factors; Tubulin Modulators

2011
Low-dose paclitaxel enhances the anti-tumor efficacy of GM-CSF surface-modified whole-tumor-cell vaccine in mouse model of prostate cancer.
    Cancer immunology, immunotherapy : CII, 2011, Volume: 60, Issue:5

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Combined Modality Therapy; Dendritic Cells; Disease Models, Animal; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Lymphocytes, Tumor-Infiltrating; Male; Mice; Mice, Inbred C57BL; Paclitaxel; Prostatic Neoplasms; T-Lymphocytes; Tumor Cells, Cultured

2011
Effects of Paclitaxel and combination of the drug with radiation therapy in an in vivo model of anaplastic thyroid carcinoma.
    Experimental oncology, 2011, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Xenograft Model Antitumor Assays

2011
Antitumour efficacy of two paclitaxel formulations for hyperthermic intraperitoneal chemotherapy (HIPEC) in an in vivo rat model.
    Pharmaceutical research, 2011, Volume: 28, Issue:7

    Topics: Animals; Antineoplastic Agents; beta-Cyclodextrins; Cell Line, Tumor; Colorectal Neoplasms; Combined Modality Therapy; Disease Models, Animal; Hyperthermia, Induced; Injections, Intraperitoneal; Magnetic Resonance Imaging; Paclitaxel; Peritoneal Neoplasms; Positron-Emission Tomography; Rats; Time Factors; Tumor Burden

2011
Abnormal muscle afferent function in a model of Taxol chemotherapy-induced painful neuropathy.
    Journal of neurophysiology, 2011, Volume: 106, Issue:1

    Topics: Action Potentials; Afferent Pathways; Animals; Antineoplastic Agents; Disease Models, Animal; Male; Muscle, Skeletal; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley

2011
Origin of restenosis after drug-eluting stent implantation in hyperglycemia is inflammatory cells and thrombus.
    Journal of atherosclerosis and thrombosis, 2011, Volume: 18, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Aorta; Body Weight; Coronary Restenosis; Diabetes Mellitus, Type 1; Disease Models, Animal; Drug-Eluting Stents; Fibrin; Humans; Hyaluronic Acid; Hyperglycemia; Inflammation; Male; Paclitaxel; Rats; Rats, Sprague-Dawley; Sirolimus; Thrombosis

2011
Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery.
    Biomaterials, 2011, Volume: 32, Issue:27

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Cross-Linking Reagents; Disease Models, Animal; Disulfides; Drug Delivery Systems; Female; Hemolysis; Humans; Kinetics; Mice; Mice, Nude; Micelles; Models, Biological; Ovarian Neoplasms; Paclitaxel; Particle Size; Spectroscopy, Near-Infrared; Tissue Distribution; Xenograft Model Antitumor Assays

2011
A novel bioluminescence orthotopic mouse model for advanced lung cancer.
    Radiation research, 2011, Volume: 176, Issue:4

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Humans; Injections; Luciferases; Luminescent Measurements; Lung; Lung Neoplasms; Mice; Molecular Imaging; Neoplasm Staging; Paclitaxel; Radiation Injuries, Experimental; Transfection

2011
Low-dose naltrexone suppresses ovarian cancer and exhibits enhanced inhibition in combination with cisplatin.
    Experimental biology and medicine (Maywood, N.J.), 2011, Volume: 236, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Proliferation; Cisplatin; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Mice; Mice, Nude; Naltrexone; Neovascularization, Pathologic; Ovarian Neoplasms; Paclitaxel; Treatment Outcome

2011
Cannabidiol prevents the development of cold and mechanical allodynia in paclitaxel-treated female C57Bl6 mice.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:4

    Topics: Analgesics; Animals; Behavior, Animal; Cannabidiol; Cold Temperature; Disease Models, Animal; Female; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Paclitaxel; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Sex Factors; Time Factors

2011
Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain.
    Neuroscience, 2011, Oct-13, Volume: 193

    Topics: Analysis of Variance; Anilides; Animals; Ankyrins; Antineoplastic Agents, Phytogenic; Capsaicin; Carbazoles; Central Nervous System; Cinnamates; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Neuralgia; Oligopeptides; Paclitaxel; Pain Measurement; Physical Stimulation; Protein Kinase C; Pyrroles; Pyrrolidinones; Receptor, PAR-2; Sulfonamides; Time Factors; TRPV Cation Channels; Tryptases; Type C Phospholipases

2011
Paclitaxel-eluting polymer film reduces locoregional recurrence and improves survival in a recurrent sarcoma model: a novel investigational therapy.
    Annals of surgical oncology, 2012, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Chondrosarcoma; Disease Models, Animal; Female; Humans; Mice; Mice, Nude; Nanoparticles; Neoplasm Recurrence, Local; Paclitaxel; Polymers; Survival Rate; Therapies, Investigational; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2012
Intracellular delivery of paclitaxel using oil-free, shell cross-linked HSA--multi-armed PEG nanocapsules.
    Biomaterials, 2011, Volume: 32, Issue:33

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Disease Models, Animal; Flow Cytometry; Humans; Male; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Nanocapsules; Neoplasms, Experimental; Paclitaxel; Polyethylene Glycols; Serum Albumin

2011
The effects of opioid receptor antagonists on electroacupuncture-produced anti-allodynia/hyperalgesia in rats with paclitaxel-evoked peripheral neuropathy.
    Brain research, 2011, Sep-26, Volume: 1414

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Electroacupuncture; Hyperalgesia; Male; Naltrexone; Narcotic Antagonists; Paclitaxel; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Random Allocation; Rats; Rats, Sprague-Dawley; Somatostatin

2011
Antinociceptive efficacy of verticinone in murine models of inflammatory pain and paclitaxel induced neuropathic pain.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:9

    Topics: Analgesics; Animals; Cevanes; Disease Models, Animal; Inflammation; Mice; Mice, Inbred ICR; Paclitaxel; Pain; Peripheral Nervous System Diseases

2011
Hyaluronic acid-paclitaxel conjugate inhibits growth of human squamous cell carcinomas of the head and neck via a hyaluronic acid-mediated mechanism.
    Oral oncology, 2011, Volume: 47, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Disease Models, Animal; Humans; Hyaluronan Receptors; Hyaluronic Acid; In Situ Nick-End Labeling; Male; Mice; Mice, Nude; Paclitaxel; Tongue Neoplasms; Transplantation, Heterologous; Treatment Outcome; Tumor Cells, Cultured

2011
Lithium attenuates peripheral neuropathy induced by paclitaxel in rats.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 110, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Lithium Chloride; Male; Motor Neurons; Neural Conduction; Neuroprotective Agents; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley

2012
Paclitaxel-loaded expansile nanoparticles in a multimodal treatment model of malignant mesothelioma.
    The Annals of thoracic surgery, 2011, Volume: 92, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Combined Modality Therapy; Disease Models, Animal; Disease Progression; Female; Humans; Mesothelioma; Mice; Nanoparticles; Paclitaxel; Xenograft Model Antitumor Assays

2011
Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192.
    The Journal of pathology, 2011, Volume: 225, Issue:3

    Topics: Animals; Cells, Cultured; Creatinine; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Drug Evaluation, Preclinical; Extracellular Matrix; Fibrosis; Gene Expression Regulation; Hypertension, Renal; Kidney; Male; MicroRNAs; Nephrectomy; Paclitaxel; Proteinuria; Rats; Rats, Wistar; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1; Tubulin Modulators

2011
Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Animals; Catheterization; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Infusions, Intra-Arterial; Lipoproteins; Mitogen-Activated Protein Kinases; Models, Biological; Monocytes; Muscle, Smooth, Vascular; Paclitaxel; Phosphorylation; PPAR gamma; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Sirolimus; Thiazolidinediones; Thromboplastin; Umbilical Arteries

2011
Paclitaxel therapy potentiates cold hyperalgesia in streptozotocin-induced diabetic rats through enhanced mitochondrial reactive oxygen species production and TRPA1 sensitization.
    Pain, 2012, Volume: 153, Issue:3

    Topics: Acetylcysteine; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Cold Temperature; Diabetes Mellitus, Experimental; Disease Models, Animal; Ganglia, Spinal; Glucose Tolerance Test; Glutathione Peroxidase; Hydrogen Peroxide; Hyperalgesia; Hypoxanthine Phosphoribosyltransferase; Male; Microscopy, Electron, Transmission; Mitochondria; Paclitaxel; Pain Measurement; Pain Threshold; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sciatic Nerve; Sensory Receptor Cells; Streptozocin; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels

2012
Delayed onset of paresis in rats with experimental intramedullary spinal cord gliosarcoma following intratumoral administration of the paclitaxel delivery system OncoGel.
    Journal of neurosurgery. Spine, 2012, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Delivery Systems; Female; Gels; Gliosarcoma; Paclitaxel; Paresis; Rats; Rats, Inbred F344; Spinal Cord Neoplasms

2012
Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma.
    Cancer letters, 2012, Jun-01, Volume: 319, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cytostatic Agents; Deoxycytidine; Disease Models, Animal; Female; Gemcitabine; Mice; Mice, SCID; Neural Cell Adhesion Molecule L1; Ovarian Neoplasms; Paclitaxel; Pancreatic Neoplasms

2012
The efficacy of abraxane on osteosarcoma xenografts in nude mice and expression of secreted protein, acidic and rich in cysteine.
    The American journal of the medical sciences, 2012, Volume: 344, Issue:3

    Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Female; Humans; Maximum Tolerated Dose; Mice; Mice, Nude; Osteonectin; Osteosarcoma; Paclitaxel; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma, Experimental; Tumor Burden; Xenograft Model Antitumor Assays

2012
Nanoparticle migration and delivery of Paclitaxel to regional lymph nodes in a large animal model.
    Journal of the American College of Surgeons, 2012, Volume: 214, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Delivery Systems; Feasibility Studies; Female; Injections, Intradermal; Lymph Nodes; Microscopy, Fluorescence; Nanoparticles; Paclitaxel; Polymers; Spectroscopy, Near-Infrared; Swine

2012
Preclinical evaluation of a novel drug-eluting balloon in an animal model of in-stent stenosis.
    Journal of biomaterials applications, 2013, Volume: 27, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Animals; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug Delivery Systems; Female; Humans; Neointima; Paclitaxel; Stents; Swine; Swine, Miniature; Wound Healing

2013
Evidence that spinal astrocytes but not microglia contribute to the pathogenesis of Paclitaxel-induced painful neuropathy.
    The journal of pain, 2012, Volume: 13, Issue:3

    Topics: Animals; Antineoplastic Agents; Astrocytes; Blotting, Western; Disease Models, Animal; Immunohistochemistry; Male; Microglia; Neuralgia; Paclitaxel; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord

2012
Evaluation of a novel paclitaxel-eluting stent with a bioabsorbable polymeric surface coating in the porcine artery injury model.
    Acta cardiologica, 2011, Volume: 66, Issue:6

    Topics: Absorbable Implants; Animals; Constriction, Pathologic; Dioxanes; Disease Models, Animal; Drug-Eluting Stents; Femoral Artery; Microscopy, Electron, Scanning; Paclitaxel; Polymers; Prostheses and Implants; Secondary Prevention; Swine; Tubulin Modulators

2011
A translation inhibitor identified in a Drosophila screen enhances the effect of ionizing radiation and taxol in mammalian models of cancer.
    Disease models & mechanisms, 2012, Volume: 5, Issue:3

    Topics: Animals; Biological Products; Cell Line, Tumor; Combined Modality Therapy; Disease Models, Animal; Drosophila melanogaster; Drug Screening Assays, Antitumor; Humans; Mice; Mutation; Neoplasms; Paclitaxel; Peptides, Cyclic; Protein Biosynthesis; Radiation, Ionizing; Xenograft Model Antitumor Assays

2012
Etodolac, a cyclooxygenase-2 inhibitor, attenuates paclitaxel-induced peripheral neuropathy in a mouse model of mechanical allodynia.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 342, Issue:1

    Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Disease Models, Animal; Drug Interactions; Duloxetine Hydrochloride; Etodolac; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mexiletine; Mice; Paclitaxel; Peripheral Nervous System Diseases; Pregabalin; Thiophenes; Tissue Distribution

2012
A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Apr-11, Volume: 32, Issue:15

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Axons; Disease Models, Animal; Drosophila; Drosophila Proteins; Eye Proteins; Female; Ganglia, Spinal; Immunohistochemistry; Larva; Mice; Microscopy, Confocal; Nerve Degeneration; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nerves; RNA Interference

2012
Long-term effects on vascular healing of bare metal stents delivered via paclitaxel-coated balloons in the porcine model of restenosis.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012, Oct-01, Volume: 80, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Animals; Cardiac Catheters; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Endothelial Cells; Equipment Design; Metals; Neointima; Paclitaxel; Prosthesis Design; Stents; Swine; Swine, Miniature; Time Factors; von Willebrand Factor

2012
Efficient inhibition of colorectal peritoneal carcinomatosis by drug loaded micelles in thermosensitive hydrogel composites.
    Nanoscale, 2012, May-21, Volume: 4, Issue:10

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Erythrocytes; Fluorouracil; Hydrogel, Polyethylene Glycol Dimethacrylate; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Peritoneal Neoplasms; Polyesters; Polyethylene Glycols; Rabbits; Temperature

2012
Targeted antivascular therapy with the apolipoprotein(a) kringle V, rhLK8, inhibits the growth and metastasis of human prostate cancer in an orthotopic nude mouse model.
    Neoplasia (New York, N.Y.), 2012, Volume: 14, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Apolipoproteins A; Disease Models, Animal; Humans; Kringles; Male; Mice; Mice, Nude; Neoplasm Metastasis; Paclitaxel; Peptide Fragments; Prostatic Neoplasms; Recombinant Proteins; Xenograft Model Antitumor Assays

2012
nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer.
    Cancer discovery, 2012, Volume: 2, Issue:3

    Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Cytidine Deaminase; Deoxycytidine; Disease Models, Animal; Drug Synergism; Gemcitabine; Mice; Paclitaxel; Pancreatic Neoplasms

2012
The antibody-based delivery of interleukin-12 to the tumor neovasculature eradicates murine models of cancer in combination with paclitaxel.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Aug-01, Volume: 18, Issue:15

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Female; Humans; Interferon-gamma; Interleukin-12; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Recombinant Fusion Proteins; Single-Chain Antibodies; Tissue Distribution; Treatment Outcome; Tumor Burden

2012
Comparative vascular responses three months after paclitaxel and everolimus-eluting stent implantation in streptozotocin-induced diabetic porcine coronary arteries.
    Cardiovascular diabetology, 2012, Jun-21, Volume: 11

    Topics: Animals; Apoptosis; Cardiovascular Agents; Cells, Cultured; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Eluting Stents; Endothelial Cells; Everolimus; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Necrosis; Neointima; Paclitaxel; Percutaneous Coronary Intervention; Prosthesis Design; Sirolimus; Swine; Time Factors; Wound Healing

2012
[Prevention of restenosis in the canine coronary stents through local delivery of paclitaxel using the double-balloon perfusion catheter].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2012, Volume: 34, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Animals; Catheters; Coronary Restenosis; Disease Models, Animal; Dogs; Injections; Paclitaxel; Stents

2012
Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice.
    Disease models & mechanisms, 2013, Volume: 6, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Axonal Transport; Axons; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Hippocampus; Humans; Mice; Mice, Knockout; Microtubules; Models, Neurological; Mutation; Neurons; Nocodazole; Paclitaxel; Spastic Paraplegia, Hereditary; Spastin; Vinblastine

2013
Electrophysiological features of the mouse tail nerves and their changes in chemotherapy induced peripheral neuropathy (CIPN).
    Journal of neuroscience methods, 2012, Aug-15, Volume: 209, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biophysics; Disease Models, Animal; Electric Stimulation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Neural Conduction; Paclitaxel; Peripheral Nervous System Diseases; Reaction Time; Rotarod Performance Test; Species Specificity; Tail; Time Factors

2012
Therapeutic application of injectable thermosensitive hydrogel in preventing local breast cancer recurrence and improving incision wound healing in a mouse model.
    Nanoscale, 2012, Sep-21, Volume: 4, Issue:18

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Female; Hydrogel, Polyethylene Glycol Dimethacrylate; Mice; Mice, Inbred BALB C; Paclitaxel; Polyesters; Polyethylene Glycols; Secondary Prevention; Temperature; Transplantation, Homologous; Wound Healing

2012
Development of a rat model of oral small molecule receptor tyrosine kinase inhibitor-induced diarrhea.
    Cancer biology & therapy, 2012, Volume: 13, Issue:13

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Disease Models, Animal; Lapatinib; Male; Paclitaxel; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases

2012
2'-Behenoyl-paclitaxel conjugate containing lipid nanoparticles for the treatment of metastatic breast cancer.
    Cancer letters, 2013, Jul-01, Volume: 334, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Female; Lipids; Mammary Neoplasms, Experimental; Mice; Nanoparticles; Neoplasm Metastasis; Paclitaxel

2013
Improving anti-tumor activity with polymeric micelles entrapping paclitaxel in pulmonary carcinoma.
    Nanoscale, 2012, Sep-28, Volume: 4, Issue:19

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Fluorescein-5-isothiocyanate; Injections, Intravenous; Injections, Subcutaneous; Lung Neoplasms; Mice; Mice, Inbred C57BL; Micelles; Paclitaxel; Polyesters; Polyethylene Glycols; Tissue Distribution; Zebrafish

2012
The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB₂ receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy.
    Molecular pain, 2012, Sep-22, Volume: 8

    Topics: Animals; Benzylamines; Chromones; Cisplatin; Cryopyrin-Associated Periodic Syndromes; Cyclams; Disease Models, Animal; Heterocyclic Compounds; Hyperalgesia; Indoles; Male; Paclitaxel; Peripheral Nervous System Diseases; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, CXCR4; Signal Transduction; Time Factors; Treatment Outcome

2012
Safety and proof-of-concept efficacy of inhaled drug loaded nano- and immunonanoparticles in a c-Raf transgenic lung cancer model.
    Current cancer drug targets, 2013, Volume: 13, Issue:1

    Topics: Administration, Inhalation; Animals; Antibodies, Immobilized; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Cell Adhesion Molecules; Disease Models, Animal; Drug Delivery Systems; Epithelial Cell Adhesion Molecule; Female; Humans; Lung; Lung Neoplasms; Male; Mice; Mice, Transgenic; Nanoparticles; Paclitaxel; Palmitates; Proto-Oncogene Proteins c-raf; Random Allocation; Surface Properties; Survival Analysis

2013
Evaluation of efficacy and dose response of different paclitaxel-coated balloon formulations in a novel swine model of iliofemoral in-stent restenosis.
    JACC. Cardiovascular interventions, 2012, Volume: 5, Issue:10

    Topics: Analysis of Variance; Angioplasty, Balloon; Animals; Antineoplastic Agents, Phytogenic; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Health Status Indicators; Hyperlipoproteinemia Type II; Male; Paclitaxel; Risk Factors; Ultrasonography

2012
Novel model for basaloid triple-negative breast cancer: behavior in vivo and response to therapy.
    Neoplasia (New York, N.Y.), 2012, Volume: 14, Issue:10

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cell Movement; Disease Models, Animal; Female; Humans; Immunoenzyme Techniques; Lung Neoplasms; Lymphatic Metastasis; Mice; Mice, Nude; Neovascularization, Pathologic; Paclitaxel; Real-Time Polymerase Chain Reaction; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2012
Targeted delivery of paclitaxel to EphA2-expressing cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Jan-01, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Delivery Systems; Female; Gene Expression; Humans; Male; Mice; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Peptides; Receptor, EphA2; Transplantation, Homologous; Tumor Burden; Xenograft Model Antitumor Assays

2013
Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:3

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Drug Delivery Systems; Drug Therapy, Combination; Female; Gels; Glioma; Humans; Neoplasm Transplantation; Paclitaxel; Rats; Rats, Inbred F344; Survival Analysis; Temozolomide

2013
Mesenchymal stromal cells primed with Paclitaxel attract and kill leukaemia cells, inhibit angiogenesis and improve survival of leukaemia-bearing mice.
    British journal of haematology, 2013, Volume: 160, Issue:6

    Topics: Animals; Cell Communication; Cell Growth Processes; Cell Line, Tumor; Disease Models, Animal; Humans; Leukemia; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Nude; Neovascularization, Pathologic; Paclitaxel; Xenograft Model Antitumor Assays

2013
Choroidal neovascularization reduced by targeted drug delivery with cationic liposome-encapsulated paclitaxel or targeted photodynamic therapy with verteporfin encapsulated in cationic liposomes.
    Molecular vision, 2013, Volume: 19

    Topics: Angiogenesis Inhibitors; Animals; Choroidal Neovascularization; Disease Models, Animal; Drug Delivery Systems; Humans; Liposomes; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Paclitaxel; Photochemotherapy; Photosensitizing Agents; Porphyrins; Prodrugs; Vascular Endothelial Growth Factor A; Verteporfin; Wet Macular Degeneration

2013
Antibody to vascular endothelial growth factor slows growth of an androgen-independent xenograft model of prostate cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:10

    Topics: Androgens; Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Disease Models, Animal; Drug Therapy, Combination; Endothelial Growth Factors; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Paclitaxel; Prostatic Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Studies with CWR22 xenografts in nude mice suggest that ZD1839 may have a role in the treatment of both androgen-dependent and androgen-independent human prostate cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:12

    Topics: Anilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Carboplatin; Disease Models, Animal; ErbB Receptors; Female; Gefitinib; Humans; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Nitriles; Paclitaxel; Prostatic Neoplasms; Protein-Tyrosine Kinases; Quinazolines; Receptors, Androgen; Testosterone; Tosyl Compounds; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2002
Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases.
    Journal of the National Cancer Institute, 2003, Mar-19, Volume: 95, Issue:6

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Blotting, Western; Bone Neoplasms; Cell Division; Disease Models, Animal; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Nude; Microcirculation; Neoplasms, Experimental; Paclitaxel; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Prostatic Neoplasms; Protein-Tyrosine Kinases; Pyrimidines; Radiographic Image Enhancement; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tumor Cells, Cultured

2003
Effects of ganglioside on paclitaxel (Taxol) induced neuropathy in rats.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003, Volume: 86, Issue:5

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electrophysiology; Female; Gangliosides; Neural Conduction; Paclitaxel; Pain Measurement; Peripheral Nervous System Diseases; Probability; Rats; Rats, Wistar; Reference Values; Sciatic Nerve; Sensation

2003
Suppression of proliferative cholangitis in a rat model by local delivery of paclitaxel.
    Journal of hepato-biliary-pancreatic surgery, 2003, Volume: 10, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bile Ducts; Cholangitis; Disease Models, Animal; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Paclitaxel; Rats; Rats, Sprague-Dawley

2003
Combined trastuzumab and paclitaxel treatment better inhibits ErbB-2-mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone.
    Cancer, 2003, Oct-01, Volume: 98, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Breast Neoplasms; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Neovascularization, Pathologic; Paclitaxel; Probability; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Reference Values; Trastuzumab; Tumor Cells, Cultured

2003
Role of sensory nerve peptides rather than mast cell histamine in paclitaxel hypersensitivity.
    American journal of respiratory and critical care medicine, 2004, Jan-01, Volume: 169, Issue:1

    Topics: Analysis of Variance; Animals; Biopsy, Needle; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Disease Models, Animal; Drug Hypersensitivity; Histamine; Immunohistochemistry; Infusions, Intravenous; Male; Mast Cells; Neurokinin A; Neuropeptides; Paclitaxel; Probability; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Sensory Receptor Cells; Substance P

2004
Effects of intraperitoneal administration of gemcitabine and paclitaxel on hepatic regeneration in rats.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2003, Volume: 14, Issue:1

    Topics: Animals; Biopsy, Needle; Deoxycytidine; Disease Models, Animal; Gemcitabine; Hepatectomy; Immunohistochemistry; Injections, Intraperitoneal; Liver; Liver Function Tests; Liver Regeneration; Male; Paclitaxel; Rats; Rats, Inbred Strains; Sensitivity and Specificity

2003
Low-dose irradiation and short-exposure suboptimal-dose paclitaxel adversely modulate metastatic potential of squamous carcinoma cells.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2003, Volume: 179, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Line, Tumor; Colony-Forming Units Assay; Cytoskeleton; Data Interpretation, Statistical; Disease Models, Animal; Humans; Immunohistochemistry; Interphase; Liver Neoplasms; Mice; Mice, SCID; Microscopy, Confocal; Neoplasm Metastasis; Paclitaxel; Radiation-Sensitizing Agents; Radiotherapy Dosage

2003
Effects of epithelial growth factor receptor (EGFR) kinase inhibitors on genetically reconstituted mouse mammary glands.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2003, Volume: 55, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Transformed; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; ErbB Receptors; Female; Image Cytometry; Injections, Intravenous; Ki-67 Antigen; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Paclitaxel; Protein-Tyrosine Kinases; Treatment Outcome

2003
Paclitaxel-induced neuropathic hypersensitivity in mice: responses in 10 inbred mouse strains.
    Life sciences, 2004, Apr-09, Volume: 74, Issue:21

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Cold Temperature; Disease Models, Animal; Female; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Paclitaxel; Pain; Peripheral Nervous System Diseases; Physical Stimulation; Species Specificity

2004
Effect of chemotherapy on primordial follicular reserve of rat: an animal model of premature ovarian failure and infertility.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2004, Volume: 44, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Infertility, Female; Injections, Intraperitoneal; Ovarian Follicle; Paclitaxel; Primary Ovarian Insufficiency; Probability; Random Allocation; Rats; Reference Values

2004
[Potentiation of focal ultrasound treatment of prostate adenocarcinoma by concomitant chemotherapy with estramustine phosphate and paclitaxel].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2004, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Combined Modality Therapy; Disease Models, Animal; Estramustine; Male; Paclitaxel; Prostatic Neoplasms; Rats; Ultrasonic Therapy

2004
Transient receptor potential vanilloid 4 is essential in chemotherapy-induced neuropathic pain in the rat.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, May-05, Volume: 24, Issue:18

    Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Calcium; Cation Transport Proteins; Cells, Cultured; Disease Models, Animal; Hyperalgesia; Hypotonic Solutions; Integrins; Ion Channels; Male; Neuralgia; Nociceptors; Oligonucleotides, Antisense; Paclitaxel; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Signal Transduction; src-Family Kinases; TRPV Cation Channels

2004
Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer.
    Journal of the National Cancer Institute, 2004, May-19, Volume: 96, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Deoxycytidine; Disease Models, Animal; DNA, Neoplasm; Docetaxel; Doxorubicin; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Epirubicin; Female; Floxuridine; Gemcitabine; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Exchange Factors; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; Paclitaxel; Proto-Oncogene Proteins; Receptor, ErbB-2; Taxoids; Transplantation, Heterologous; Trastuzumab; Tumor Stem Cell Assay; Up-Regulation; Vinblastine; Vinorelbine

2004
Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neu in a murine mammary carcinoma model.
    Breast cancer research : BCR, 2004, Volume: 6, Issue:4

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Breast Neoplasms; Cancer Vaccines; Carcinoma; Cell Line; Combined Modality Therapy; Disease Models, Animal; Doxorubicin; Drug Administration Schedule; Epitopes; Female; Humans; Interferon-gamma; Lymphocyte Activation; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Paclitaxel; Receptor, ErbB-2; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic; Vaccines, DNA

2004
Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: biocompatibility and efficacy determinations in rabbits.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53, Issue:8

    Topics: Animals; Arthritis; Biocompatible Materials; Chitosan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Inflammation; Injections, Intra-Articular; Joints; Materials Testing; Microspheres; Paclitaxel; Rabbits; Synovial Fluid; Treatment Outcome

2004
Angiogenesis gene expression profiling in xenograft models to study cellular interactions.
    Experimental cell research, 2004, Oct-01, Volume: 299, Issue:2

    Topics: Angiogenesis Inhibitors; Angiogenic Proteins; Animals; Antineoplastic Agents; Base Sequence; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Mice; Molecular Sequence Data; Neovascularization, Pathologic; Ovarian Neoplasms; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Nucleic Acid; Skin Neoplasms; Transplantation, Heterologous

2004
Efficacy of transferrin-conjugated paclitaxel-loaded nanoparticles in a murine model of prostate cancer.
    International journal of cancer, 2004, Nov-01, Volume: 112, Issue:2

    Topics: Animals; Biocompatible Materials; Disease Models, Animal; Drug Delivery Systems; Male; Mice; Mice, Nude; Nanotechnology; Paclitaxel; Pharmaceutical Vehicles; Polyethylene Glycols; Prostatic Neoplasms; Survival Analysis; Transferrin

2004
Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resista
    Cancer, 2004, Oct-15, Volume: 101, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cyclooxygenase 2; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Intramolecular Oxidoreductases; Irinotecan; Isoenzymes; Liver Neoplasms; Lung Neoplasms; Membrane Proteins; Mice; Mice, Nude; Neoplasm Proteins; Organoplatinum Compounds; Ornithine Decarboxylase; Oxaliplatin; Paclitaxel; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Survival Rate; Transplantation, Heterologous; Vault Ribonucleoprotein Particles

2004
Antimetastatic and anticancer activity of S-1, a new oral dihydropyrimidine-dehydrogenase-inhibiting fluoropyrimidine, alone and in combination with paclitaxel in an orthotopically implanted human breast cancer model.
    International journal of oncology, 2004, Volume: 25, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease Models, Animal; Drug Combinations; Female; Mice; Mice, SCID; Neoplasm Metastasis; Oxonic Acid; Paclitaxel; Pyridines; Tegafur; Transplantation, Heterologous

2004
Microtubule-stabilising drugs may be therapeutic in AD.
    The Lancet. Neurology, 2005, Volume: 4, Issue:2

    Topics: Alzheimer Disease; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Humans; Microtubules; Paclitaxel; tau Proteins

2005
Use of a tacrolimus-eluting stent to inhibit neointimal hyperplasia in a porcine coronary model.
    The Journal of invasive cardiology, 2005, Volume: 17, Issue:3

    Topics: Animals; Cell Survival; Coated Materials, Biocompatible; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Immunosuppressive Agents; Male; Paclitaxel; Stents; Swine; Tacrolimus; Tunica Intima

2005
An inhibitor of Bcl-2 family proteins induces regression of solid tumours.
    Nature, 2005, Jun-02, Volume: 435, Issue:7042

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Carcinoma, Small Cell; Cell Line, Tumor; Cytochromes c; Disease Models, Animal; Drug Synergism; Humans; Lymphoma; Magnetic Resonance Spectroscopy; Mice; Mitochondria; Models, Molecular; Neoplasms; Nitrophenols; Paclitaxel; Piperazines; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Sulfonamides; Survival Rate

2005
Spinal glial glutamate transporters downregulate in rats with taxol-induced hyperalgesia.
    Neuroscience letters, 2005, Sep-23, Volume: 386, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Antineoplastic Agents, Phytogenic; Cell Communication; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hyperalgesia; Male; Neuroglia; Nociceptors; Paclitaxel; Peripheral Nervous System Diseases; Posterior Horn Cells; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Symporters; Synaptic Transmission

2005
Comparative study of tacrolimus and paclitaxel stent coating in the porcine coronary model.
    Zeitschrift fur Kardiologie, 2005, Volume: 94, Issue:7

    Topics: Animals; Blood Vessel Prosthesis; Coated Materials, Biocompatible; Coronary Restenosis; Coronary Vessels; Delayed-Action Preparations; Disease Models, Animal; Graft Occlusion, Vascular; Immunosuppressive Agents; Paclitaxel; Swine; Swine, Miniature; Tacrolimus; Treatment Outcome

2005
In vivo evaluation of ixabepilone (BMS247550), a novel epothilone B derivative, against pediatric cancer models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 1

    Topics: Animals; Area Under Curve; Brain Neoplasms; Cell Line, Tumor; Clinical Trials as Topic; Disease Models, Animal; Dose-Response Relationship, Drug; Epothilones; Female; Humans; Maximum Tolerated Dose; Mice; Mice, SCID; Microtubules; Mitosis; Models, Chemical; Neoplasm Transplantation; Neuroblastoma; Osteosarcoma; Paclitaxel; Rhabdomyosarcoma; Time Factors; Treatment Outcome; Vinca Alkaloids; Wilms Tumor

2005
Vascular endothelial growth factor trap combined with paclitaxel strikingly inhibits tumor and ascites, prolonging survival in a human ovarian cancer model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 1

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ascites; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Mice; Mice, Nude; Necrosis; Neoplasm Metastasis; Neoplasm Transplantation; Ovarian Neoplasms; Paclitaxel; Time Factors; Treatment Outcome; Vascular Endothelial Growth Factor A

2005
A cannabinoid agonist, WIN 55,212-2, reduces neuropathic nociception induced by paclitaxel in rats.
    Pain, 2005, Volume: 118, Issue:1-2

    Topics: Analgesics; Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Benzoxazines; Cannabinoids; Disease Models, Animal; Hot Temperature; Humans; Hyperalgesia; Male; Morpholines; Naphthalenes; Neuralgia; Paclitaxel; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Wistar; Sensory Thresholds; Touch; Treatment Outcome

2005
Role of the antiangiogenetic drug paclitaxel on healing of intestinal anastomosis: an experimental study.
    Techniques in coloproctology, 2005, Volume: 9, Issue:3

    Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Antineoplastic Agents, Phytogenic; Colectomy; Colon; Disease Models, Animal; Injections, Intraperitoneal; Intraoperative Care; Paclitaxel; Probability; Random Allocation; Rats; Rats, Wistar; Sensitivity and Specificity; Statistics, Nonparametric; Tensile Strength; Wound Healing

2005
Enhancement of antitumor effect of paclitaxel in combination with immunomodulatory Withania somnifera on benzo(a)pyrene induced experimental lung cancer.
    Chemico-biological interactions, 2006, Feb-25, Volume: 159, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Disease Models, Animal; Immunoglobulins; Immunologic Factors; Lung Neoplasms; Male; Medicine, Ayurvedic; Mice; Paclitaxel; Phytotherapy; Plant Extracts; Withania

2006
Therapeutic efficacy of prosaposin-derived peptide on different models of allodynia.
    Pain, 2006, Volume: 121, Issue:1-2

    Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Diabetes Complications; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Nerve Growth Factors; Paclitaxel; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatica; Skin; Time Factors

2006
[The effect of paclitaxel-eluting stents on restenosis].
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2006, Volume: 6, Issue:1

    Topics: Animals; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Humans; Paclitaxel; Platelet Aggregation Inhibitors; Random Allocation; Secondary Prevention; Stents; Swine; Ticlopidine; Tunica Intima; Ultrasonography, Interventional

2006
Ribonucleic acid interference targeting S100A4 (Mts1) suppresses tumor growth and metastasis of anaplastic thyroid carcinoma in a mouse model.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:6

    Topics: Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Paclitaxel; RNA Interference; S100 Calcium-Binding Protein A4; S100 Proteins; Thyroid Neoplasms

2006
Paclitaxel-coated expanded polytetrafluoroethylene haemodialysis grafts inhibit neointimal hyperplasia in porcine model of graft stenosis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Arteriovenous Shunt, Surgical; Blood Vessel Prosthesis; Coated Materials, Biocompatible; Disease Models, Animal; Fluorocarbon Polymers; Graft Occlusion, Vascular; Hyperplasia; In Vitro Techniques; Male; Paclitaxel; Prosthesis Design; Renal Dialysis; Swine; Tunica Intima

2006
A novel paclitaxel-eluting porous carbon-carbon nanoparticle coated, nonpolymeric cobalt-chromium stent: evaluation in a porcine model.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2006, Volume: 67, Issue:5

    Topics: Analysis of Variance; Animals; Carbon; Chromium; Coated Materials, Biocompatible; Cobalt; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Lactic Acid; Nanostructures; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Stents; Swine

2006
Dual epidermal growth factor receptor and vascular endothelial growth factor receptor inhibition with NVP-AEE788 for the treatment of aggressive follicular thyroid cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jun-01, Volume: 12, Issue:11 Pt 1

    Topics: Adenocarcinoma, Follicular; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; ErbB Receptors; Humans; Male; Mice; Mice, Nude; Paclitaxel; Phosphorylation; Predictive Value of Tests; Prognosis; Purines; Receptors, Vascular Endothelial Growth Factor; Structure-Activity Relationship; Thyroid Neoplasms; Xenograft Model Antitumor Assays

2006
Effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in combination with paclitaxel (Taxol) on prostate Cancer LNCaP cells cultured in vitro or grown as xenograft tumors in immunodeficient mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jun-01, Volume: 12, Issue:11 Pt 1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Humans; Injections, Intraperitoneal; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Nude; Mice, SCID; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Treatment Outcome; Xenograft Model Antitumor Assays

2006
Preclinical pharmacologic evaluation of MST-997, an orally active taxane with superior in vitro and in vivo efficacy in paclitaxel- and docetaxel-resistant tumor models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jun-01, Volume: 12, Issue:11 Pt 1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Binding Sites; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; In Situ Hybridization, Fluorescence; Injections, Intravenous; Mice; Mice, Nude; Molecular Conformation; Paclitaxel; Stereoisomerism; Taxoids; Tubulin; Xenograft Model Antitumor Assays

2006
Silica-induced apoptosis in alveolar macrophages: evidence of in vivo thiol depletion and the activation of mitochondrial pathway.
    Journal of toxicology and environmental health. Part A, 2006, Volume: 69, Issue:13

    Topics: Acetylcysteine; Alkaloids; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzylisoquinolines; Caspase 3; Caspases; Cysteine; Cytochromes c; Disease Models, Animal; Glutathione; Inflammation Mediators; Macrophages, Alveolar; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; Oxidative Stress; Paclitaxel; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Silicon Dioxide; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha

2006
Perivascular paclitaxel wraps block arteriovenous graft stenosis in a pig model.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Arteriovenous Shunt, Surgical; Disease Models, Animal; Drug Implants; Graft Occlusion, Vascular; Paclitaxel; Swine; Treatment Outcome

2006
Synergistic antitumor activity of taxol and immunotoxin SS1P in tumor-bearing mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Aug-01, Volume: 12, Issue:15

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Humans; Injections, Intraperitoneal; Injections, Subcutaneous; Mesothelin; Mice; Mice, Nude; Paclitaxel; Structure-Activity Relationship; Xenograft Model Antitumor Assays

2006
NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel.
    British journal of cancer, 2006, Sep-04, Volume: 95, Issue:5

    Topics: Animals; Collagen Type III; Disease Models, Animal; Female; Humans; Lung; Lung Neoplasms; Mice; Mice, Inbred C57BL; Paclitaxel; Radiation-Sensitizing Agents; Rats; Rats, Inbred Lew

2006
A mouse model for the molecular characterization of brca1-associated ovarian carcinoma.
    Cancer research, 2006, Sep-15, Volume: 66, Issue:18

    Topics: Animals; BRCA1 Protein; Cell Transformation, Neoplastic; Cisplatin; Disease Models, Animal; DNA Damage; Epithelial Cells; Female; Genes, BRCA1; Genes, myc; Genes, p53; Mice; Mice, Transgenic; Ovarian Neoplasms; Ovary; Paclitaxel; Proto-Oncogene Proteins c-myc; Tumor Suppressor Protein p53

2006
Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells.
    Experimental neurology, 2007, Volume: 203, Issue:1

    Topics: Activating Transcription Factor 3; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents, Phytogenic; CD11b Antigen; Chemotaxis, Leukocyte; Disease Models, Animal; Ganglia, Spinal; Glial Fibrillary Acidic Protein; Hyperalgesia; Injections, Intravenous; Macrophages; Male; Microglia; Neurons, Afferent; Paclitaxel; Peripheral Nerves; Peripheral Nervous System Diseases; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Satellite Cells, Perineuronal; Schwann Cells

2007
Paclitaxel delivered to adventitia attenuates neointima formation without compromising re-endothelialization after angioplasty in a porcine restenosis model.
    Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 2006, Volume: 13, Issue:5

    Topics: Analysis of Variance; Angioplasty, Balloon; Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; Connective Tissue; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Femoral Artery; Fluorescent Antibody Technique; Graft Occlusion, Vascular; Hyperplasia; Immunohistochemistry; Injections, Intra-Arterial; Ki-67 Antigen; Myocytes, Smooth Muscle; Paclitaxel; Platelet Endothelial Cell Adhesion Molecule-1; Research Design; Reverse Transcriptase Polymerase Chain Reaction; Swine; Tunica Intima; Tunica Media; von Willebrand Factor

2006
Chemotherapy-evoked painful peripheral neuropathy: analgesic effects of gabapentin and effects on expression of the alpha-2-delta type-1 calcium channel subunit.
    Neuroscience, 2007, Jan-19, Volume: 144, Issue:2

    Topics: Amines; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Male; Motor Activity; Neuralgia; Paclitaxel; Pain Measurement; Protein Subunits; Rats; Rats, Sprague-Dawley; Time Factors; Vincristine

2007
Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases reduces growth and metastasis of human salivary adenoid cystic carcinoma in an orthotopic nude mouse model.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:11

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Adenoid Cystic; Cisplatin; Disease Models, Animal; ErbB Receptors; Humans; Male; Mice; Mice, Nude; Neoplasm Metastasis; Oncogene Protein v-akt; Paclitaxel; Parotid Gland; Phosphorylation; Purines; Salivary Gland Neoplasms; Taxoids; Vascular Endothelial Growth Factor Receptor-2

2006
Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats.
    Brain, behavior, and immunity, 2007, Volume: 21, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; CD11b Antigen; Cytokines; Disease Models, Animal; Ganglia, Spinal; Genetic Therapy; Hyperalgesia; Injections, Spinal; Interleukin-10; Interleukin-1beta; Male; Meninges; Neuroglia; Paclitaxel; Pain Threshold; Peripheral Nervous System Diseases; Plasmids; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; RNA, Messenger; Spinal Cord; Tumor Necrosis Factor-alpha

2007
Modified paclitaxel-loaded nanoparticles for inhibition of hyperplasia in a rabbit arterial balloon injury model.
    Pharmaceutical research, 2007, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carotid Artery Injuries; Catheterization; Chromatography, High Pressure Liquid; Diffusion; Disease Models, Animal; Endothelium, Vascular; Hyperplasia; Microscopy, Electron, Transmission; Nanoparticles; Paclitaxel; Particle Size; Polyglactin 910; Polyvinyl Alcohol; Rabbits; Solubility; Time Factors; Treatment Outcome; Tunica Intima

2007
Coating with paclitaxel improves graft survival in a porcine model of haemodialysis graft stenosis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:10

    Topics: Animals; Coated Materials, Biocompatible; Constriction, Pathologic; Disease Models, Animal; Graft Rejection; Graft Survival; Male; Paclitaxel; Polytetrafluoroethylene; Prosthesis Design; Renal Dialysis; Swine; Time Factors; Tubulin Modulators

2007
Paclitaxel in the treatment of retinal tumors of LH beta-Tag murine transgenic model of retinoblastoma.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Conjunctiva; Disease Models, Animal; Injections, Intralesional; Linear Models; Luteinizing Hormone, beta Subunit; Mice; Mice, Transgenic; Paclitaxel; Retinal Neoplasms; Retinoblastoma

2007
Nucleolar enlargement, nuclear eccentricity and altered cell body immunostaining characteristics of large-sized sensory neurons following treatment of rats with paclitaxel.
    Neurotoxicology, 2007, Volume: 28, Issue:6

    Topics: Activating Transcription Factor 3; Animals; Antineoplastic Agents, Phytogenic; Cell Nucleolus; Cell Size; Disease Models, Animal; Female; Ganglia, Spinal; H-Reflex; Immunohistochemistry; Neural Conduction; Neurons, Afferent; Neuropeptide Y; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nervous System Diseases; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Reaction Time; Up-Regulation

2007
Molecular mechanisms of paclitaxel and NM-3 on human gastric cancer in a severe combined immune deficiency mice orthotopic implantation model.
    World journal of gastroenterology, 2007, Aug-14, Volume: 13, Issue:30

    Topics: Adenocarcinoma; Animals; Antigens, Viral, Tumor; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Humans; Isocoumarins; Male; Mice; Mice, Nude; Mice, SCID; Paclitaxel; Stomach Neoplasms; Viral Core Proteins; Xenograft Model Antitumor Assays

2007
Inhibition of pseudointimal hyperplasia in swine TIPS models: the efficacy of local delivery of paclitaxel using a perforated balloon catheter.
    The British journal of radiology, 2007, Volume: 80, Issue:957

    Topics: Angioplasty, Balloon; Animals; Antineoplastic Agents, Phytogenic; Catheterization; Disease Models, Animal; Drug Delivery Systems; Hepatic Veins; Hyperplasia; Paclitaxel; Portasystemic Shunt, Transjugular Intrahepatic; Swine; Treatment Outcome

2007
Pimecrolimus and dual pimecrolimus-paclitaxel eluting stents decrease neointimal proliferation in a porcine model.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2007, Nov-15, Volume: 70, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Vessel Prosthesis Implantation; Calcineurin Inhibitors; Cell Proliferation; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug Combinations; Follow-Up Studies; Graft Occlusion, Vascular; Immunosuppressive Agents; Paclitaxel; Stents; Swine; Tacrolimus; Treatment Outcome; Tunica Intima

2007
Comparison of intraperitoneal with intravenous administration of taxol in experimental peritoneal carcinomatosis.
    Chemotherapy, 2007, Volume: 53, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Injections, Intraperitoneal; Injections, Intravenous; Liver Neoplasms, Experimental; Male; Paclitaxel; Peritoneal Neoplasms; Rats; Rats, Inbred ACI; Rats, Inbred Strains

2007
Anti-inflammatory effect of abciximab-coated stent in a porcine coronary restenosis model.
    Journal of Korean medical science, 2007, Volume: 22, Issue:5

    Topics: Abciximab; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Arteries; Constriction, Pathologic; Coronary Restenosis; Disease Models, Animal; Drug-Eluting Stents; Female; Hyperplasia; Immunoglobulin Fab Fragments; Inflammation; Paclitaxel; Sirolimus; Swine; Tunica Intima

2007
Dual drug release from stents-will we be happy with thing one and thing two?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2007, Nov-15, Volume: 70, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Vessel Prosthesis Implantation; Calcineurin Inhibitors; Cell Proliferation; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug Combinations; Graft Occlusion, Vascular; Immunosuppressive Agents; Paclitaxel; Stents; Swine; Tacrolimus; Treatment Outcome

2007
Application of paclitaxel-eluting metal stents in renal artery of pig model.
    Journal of endourology, 2007, Volume: 21, Issue:12

    Topics: Angiography; Angioscopy; Animals; Antineoplastic Agents, Phytogenic; Blood Vessel Prosthesis Implantation; Coated Materials, Biocompatible; Disease Models, Animal; Female; Paclitaxel; Prosthesis Design; Renal Artery Obstruction; Stents; Swine; Treatment Outcome

2007
Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-L-carnitine: effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells.
    Experimental neurology, 2008, Volume: 210, Issue:1

    Topics: Acetylcarnitine; Animals; Axons; Behavior, Animal; Disease Models, Animal; Drug Interactions; Langerhans Cells; Male; Microscopy, Electron, Transmission; Mitochondria; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Skin

2008
Short- and long-term effects of a novel paclitaxel coated stent in the porcine coronary model.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2008, Volume: 97, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Animals; Coronary Angiography; Coronary Disease; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Follow-Up Studies; Paclitaxel; Probability; Random Allocation; Risk Factors; Survival Rate; Swine; Swine, Miniature; Time Factors; Treatment Outcome

2008
Paclitaxel associated with cholesterol-rich nanoemulsions promotes atherosclerosis regression in the rabbit.
    Atherosclerosis, 2008, Volume: 197, Issue:2

    Topics: Animals; Anticholesteremic Agents; Aorta, Thoracic; Atherosclerosis; Cholesterol; Disease Models, Animal; Drug Delivery Systems; Emulsions; Male; Paclitaxel; Rabbits

2008
Inflammation and delayed endothelization with overlapping drug-eluting stents in a porcine model of in-stent restenosis.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:3

    Topics: Animals; Cell Proliferation; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Endothelium, Vascular; Female; Hyperplasia; Inflammation; Paclitaxel; Sirolimus; Stents; Swine; Tunica Intima

2008
High energy shock waves (HESW) increase paclitaxel efficacy in a syngeneic model of breast cancer.
    Technology in cancer research & treatment, 2008, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-Associated Death Protein; Breast Neoplasms; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Female; Gene Expression; High-Energy Shock Waves; In Situ Nick-End Labeling; Paclitaxel; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction

2008
Imaging paclitaxel (chemotherapy)-induced tumor apoptosis with 99mTc C2A, a domain of synaptotagmin I: a preliminary study.
    Nuclear medicine and biology, 2008, Volume: 35, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Disease Models, Animal; DNA Fragmentation; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Mice; Paclitaxel; Protein Structure, Tertiary; Radioligand Assay; Radionuclide Imaging; Radiopharmaceuticals; Synaptotagmin I; Technetium; Tissue Distribution

2008
Cures for polycystic kidney diseases?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:10

    Topics: Animals; Disease Models, Animal; Humans; Paclitaxel; Polycystic Kidney Diseases

1994
Taxol inhibits progression of congenital polycystic kidney disease.
    Nature, 1994, Apr-21, Volume: 368, Issue:6473

    Topics: Animals; Body Weight; Cells, Cultured; Disease Models, Animal; Humans; Kidney; Mice; Microtubules; Organ Size; Paclitaxel; Polycystic Kidney Diseases

1994
Regression of collagen-induced arthritis with taxol, a microtubule stabilizer.
    Arthritis and rheumatism, 1994, Volume: 37, Issue:6

    Topics: Animals; Antibodies; Arthritis; Collagen; Disease Models, Animal; Female; Immunoglobulin G; Paclitaxel; Radiography; Rats; Remission Induction; Synovial Membrane

1994
Application of the ATP-cell viability assay for assessment of in vitro radiation treatment response in gynecologic cancer cell lines.
    Contributions to gynecology and obstetrics, 1994, Volume: 19

    Topics: Adenosine Triphosphate; Animals; Cell Survival; Combined Modality Therapy; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Screening Assays, Antitumor; Female; Ovarian Neoplasms; Paclitaxel; Radiation Tolerance; Radiotherapy Dosage; Tumor Cells, Cultured; Uterine Cervical Neoplasms

1994
The antitumoral effect of the immunomodulator AS101 and paclitaxel (Taxol) in a murine model of lung adenocarcinoma.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Feb-01, Volume: 156, Issue:3

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cytotoxicity, Immunologic; Disease Models, Animal; Drug Therapy, Combination; Ethylenes; Female; Lung Neoplasms; Macrophage Activation; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nitric Oxide; Paclitaxel; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1996
Effect of the microtubule-disrupting drug colchicine on rat cerulein-induced pancreatitis in comparison with the microtubule stabilizer taxol.
    Pancreas, 1995, Volume: 11, Issue:3

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Colchicine; Disease Models, Animal; Gastrointestinal Agents; Male; Microscopy, Electron; Microscopy, Fluorescence; Microtubules; Paclitaxel; Pancreatic Juice; Pancreatitis; Rats; Rats, Wistar; Trypsin; Tubulin

1995
Skin ulceration potential of paclitaxel in a mouse skin model in vivo.
    Cancer, 1996, Jul-01, Volume: 78, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dose-Response Relationship, Drug; Extravasation of Diagnostic and Therapeutic Materials; Female; Injections, Intradermal; Mice; Mice, Inbred BALB C; Paclitaxel; Skin Ulcer

1996
Effects of amifostine and paclitaxel on growth of human ovarian carcinoma xenografts in the severe combined immune-deficient mouse: preliminary results.
    Seminars in oncology, 1996, Volume: 23, Issue:4 Suppl 8

    Topics: Amifostine; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Mice; Mice, SCID; Ovarian Neoplasms; Paclitaxel; Radiation-Protective Agents; Tumor Cells, Cultured

1996
Acute in vivo resistance in high-dose therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cyclophosphamide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Mammary Neoplasms, Experimental; Melphalan; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Paclitaxel; Thiotepa

1998
Taxol involution of collagen-induced arthritis: ultrastructural correlation with the inhibition of synovitis and neovascularization.
    Clinical immunology and immunopathology, 1998, Volume: 86, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Arthritis, Rheumatoid; Collagen; Corrosion Casting; Disease Models, Animal; Female; Humans; Microscopy, Electron; Microscopy, Electron, Scanning; Neovascularization, Pathologic; Paclitaxel; Rats; Rats, Inbred Strains; Synovial Membrane; Synovitis

1998
Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:4

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Combined Modality Therapy; Disease Models, Animal; Drug Synergism; Female; Gene Transfer Techniques; Genes, p53; Genetic Therapy; Genetic Vectors; Head and Neck Neoplasms; Humans; Male; Mammary Neoplasms, Animal; Mice; Microtubules; Neoplasms; Ovarian Neoplasms; Paclitaxel; Prostatic Neoplasms; Transduction, Genetic; Treatment Outcome; Tumor Cells, Cultured

1998
Cyclosporin A enhances paclitaxel toxicity against leukemia and respiratory epithelial cancers.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclosporine; Cytokines; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Glycerol; Growth Substances; Humans; Immunosuppressive Agents; Leukemia; Mice; Paclitaxel; Respiratory Tract Neoplasms; Survival Rate; Treatment Outcome; Tumor Cells, Cultured

1997
Simultaneous genetic chemoprotection of normal marrow cells and genetic chemosensitization of breast cancer cells in a mouse cancer gene therapy model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Chemoprevention; Disease Models, Animal; DNA, Complementary; Drug Resistance, Neoplasm; Female; Genetic Therapy; Humans; Mammary Neoplasms, Animal; Metallothionein; Mice; Mice, Inbred BALB C; Paclitaxel; Promoter Regions, Genetic; Retroviridae; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1997
Tyrosine kinase inhibitor emodin suppresses growth of HER-2/neu-overexpressing breast cancer cells in athymic mice and sensitizes these cells to the inhibitory effect of paclitaxel.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Division; Disease Models, Animal; Drug Synergism; Emodin; Enzyme Inhibitors; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Receptor, ErbB-2; Tumor Cells, Cultured; Tyrosine

1999
Paclitaxel: an effective antineoplastic agent in the treatment of xenotransplanted hepatoblastoma.
    Medical and pediatric oncology, 1999, Volume: 32, Issue:3

    Topics: alpha-Fetoproteins; Animals; Antibodies; Antineoplastic Agents, Phytogenic; Cell Division; Child, Preschool; Disease Models, Animal; Female; Hepatoblastoma; Humans; Immunohistochemistry; Infant; Liver Neoplasms; Mice; Mice, Nude; Paclitaxel; Transplantation, Heterologous; Tubulin

1999
The common marmoset as a target preclinical primate model for cytokine and gene therapy studies.
    Blood, 1999, May-01, Volume: 93, Issue:9

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Callithrix; Cells, Cultured; Cytokines; Disease Models, Animal; DNA, Viral; Docetaxel; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Granulocyte Colony-Stimulating Factor; Granulocytes; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Lymphocytes; Paclitaxel; Polymerase Chain Reaction; Retroviridae; Stromal Cells; Taxoids; Transplantation, Autologous

1999
Synthesis of taxoids 5. Synthesis and evaluation of novel water-soluble prodrugs of a 3'-desphenyl-3'-cyclopropyl analogue of docetaxel.
    Bioorganic & medicinal chemistry letters, 1999, Jun-21, Volume: 9, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Docetaxel; Drug Screening Assays, Antitumor; Humans; Melanoma, Experimental; Mice; Neoplasm Transplantation; Paclitaxel; Prodrugs; Solubility; Structure-Activity Relationship; Taxoids; Transplantation, Heterologous; Tumor Cells, Cultured; Water

1999
Marked antiangiogenic and antitumor efficacy of AG3340 in chemoresistant human non-small cell lung cancer tumors: single agent and combination chemotherapy studies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Drug Interactions; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Organic Chemicals; Paclitaxel; Transplantation, Heterologous; Treatment Outcome; Tumor Cells, Cultured

1999
Inhalation chemotherapy for macroscopic primary or metastatic lung tumors: proof of principle using dogs with spontaneously occurring tumors as a model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:9

    Topics: Administration, Inhalation; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dog Diseases; Dogs; Doxorubicin; Female; Lung Neoplasms; Male; Melanoma; Paclitaxel; Sarcoma

1999
Biological and pharmacological characterisation of three models of human ovarian carcinoma established in nude mice: use of the CA125 tumour marker to predict antitumour activity.
    International journal of oncology, 1999, Volume: 15, Issue:6

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; CA-125 Antigen; Cisplatin; Disease Models, Animal; Female; Humans; Mice; Mice, Congenic; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Paclitaxel; Survival Analysis; Transplantation, Heterologous; Tumor Cells, Cultured

1999
Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides.
    Journal of the National Cancer Institute, 2000, Jan-05, Volume: 92, Issue:1

    Topics: Androgens; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Male; Mammary Neoplasms, Experimental; Mice; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Oligonucleotides, Antisense; Paclitaxel; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm

2000
Enhancement of paclitaxel delivery to solid tumors by apoptosis-inducing pretreatment: effect of treatment schedule.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Count; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Paclitaxel; Tritium; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2001
Calcitriol (1,25-dihydroxycholecalciferol) enhances paclitaxel antitumor activity in vitro and in vivo and accelerates paclitaxel-induced apoptosis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Calcitriol; Calcium Channel Agonists; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression; Mice; Paclitaxel; Tumor Cells, Cultured; Tumor Stem Cell Assay

2001
Schedule dependency of antitumor activity in combination therapy with capecitabine/5'-deoxy-5-fluorouridine and docetaxel in breast cancer models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Deoxycytidine; Disease Models, Animal; Docetaxel; Drug Administration Schedule; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Paclitaxel; Taxoids; Thymidine Phosphorylase; Tumor Cells, Cultured; Up-Regulation; Xenograft Model Antitumor Assays

2001
Paclitaxel stent coating inhibits neointimal hyperplasia at 4 weeks in a porcine model of coronary restenosis.
    Circulation, 2001, May-08, Volume: 103, Issue:18

    Topics: Animals; Coronary Angiography; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Graft Occlusion, Vascular; Hyperplasia; Infusion Pumps, Implantable; Male; Paclitaxel; Stents; Surface Properties; Swine, Miniature; Tunica Intima

2001
BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Survival; Colonic Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Epothilones; Epoxy Compounds; Female; Humans; Infusions, Parenteral; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Ovarian Neoplasms; Paclitaxel; Pancreatic Neoplasms; Sarcoma; Thiazoles; Tubulin; Tumor Cells, Cultured; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

2001
A preclinical model for experimental chemotherapy of human head and neck cancer.
    International journal of oncology, 2001, Volume: 18, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Body Weight; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Disease Models, Animal; Docetaxel; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Ifosfamide; Methotrexate; Mice; Mice, Nude; Paclitaxel; Survival Rate; Taxoids

2001
Use of antisense oligonucleotides targeting the antiapoptotic gene, clusterin/testosterone-repressed prostate message 2, to enhance androgen sensitivity and chemosensitivity in prostate cancer.
    Urology, 2001, Volume: 58, Issue:2 Suppl 1

    Topics: Androgen Antagonists; Animals; Antineoplastic Agents, Hormonal; Apoptosis; Calcium Channel Blockers; Cell Death; Clusterin; Disease Models, Animal; Drug Synergism; Glycoproteins; Humans; Male; Mice; Molecular Chaperones; Neoadjuvant Therapy; Oligonucleotides, Antisense; Orchiectomy; Paclitaxel; Prostatic Neoplasms; Up-Regulation; Xenograft Model Antitumor Assays

2001
Leukaemia inhibitory factor abrogates Paclitaxel-induced axonal atrophy in the Wistar rat.
    Brain research, 2001, Aug-24, Volume: 911, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Axons; Calcitonin Gene-Related Peptide; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Spinal; Growth Inhibitors; Immunohistochemistry; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Nerve Degeneration; Neural Conduction; Neurons, Afferent; Paclitaxel; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Substance P

2001
Local delivery of paclitaxel using the double-balloon perfusion catheter before stenting in the porcine coronary artery.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2001, Volume: 53, Issue:4

    Topics: Angioplasty, Balloon; Animals; Antineoplastic Agents, Phytogenic; Catheterization; Coronary Vessels; Disease Models, Animal; Drug Delivery Systems; Electrocardiography; Infusion Pumps; Paclitaxel; Stents; Swine

2001
VIP receptor antagonists and chemotherapeutic drugs inhibit the growth of breast cancer cells.
    Breast cancer research and treatment, 2001, Volume: 68, Issue:1

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cyclic AMP; Disease Models, Animal; Doxorubicin; Drug Synergism; Female; Genes, fos; Humans; Iodine Radioisotopes; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neurotensin; Paclitaxel; Protein Binding; Receptors, Vasoactive Intestinal Peptide; Recombinant Fusion Proteins; RNA, Messenger; Thymidine; Transplantation, Heterologous; Tumor Cells, Cultured; Vasoactive Intestinal Peptide

2001
Paclitaxel-coated Gianturco-Roubin II (GR II) stents reduce neointimal hyperplasia in a porcine coronary in-stent restenosis model.
    Coronary artery disease, 2001, Volume: 12, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Coronary Angiography; Coronary Vessels; Disease Models, Animal; Graft Occlusion, Vascular; Hyperplasia; Paclitaxel; Stents; Swine; Tunica Intima

2001
A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel.
    Pain, 2001, Volume: 94, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Cold Temperature; Disease Models, Animal; Hindlimb; Hot Temperature; Hyperalgesia; Male; Motor Activity; Paclitaxel; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Tail

2001
Inhibition of phosphatidylinositol 3'-kinase increases efficacy of paclitaxel in in vitro and in vivo ovarian cancer models.
    Cancer research, 2002, Feb-15, Volume: 62, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Division; Chromones; Disease Models, Animal; Drug Synergism; Enzyme Inhibitors; Female; Humans; Mice; Mice, Nude; Morpholines; Ovarian Neoplasms; Paclitaxel; Phosphoinositide-3 Kinase Inhibitors; Tumor Cells, Cultured

2002
HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma.
    Nature medicine, 2002, Volume: 8, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Endothelial Growth Factors; Endothelium, Vascular; Extraembryonic Membranes; Female; Fibroblast Growth Factor 2; HIV Protease Inhibitors; Humans; Indinavir; Lymphokines; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Paclitaxel; Saquinavir; Sarcoma, Kaposi; Skin; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Combined modality radioimmunotherapy. Promise and peril.
    Cancer, 2002, Feb-15, Volume: 94, Issue:4 Suppl

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Cetuximab; Combined Modality Therapy; Disease Models, Animal; Female; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Mice, Nude; Mortality; Neoplasm Transplantation; Neoplasms, Experimental; Oligopeptides; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Radioimmunotherapy; Radiotherapy; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2002
Pharmacokinetics of paclitaxel administered by hyperthermic retrograde isolated lung perfusion techniques.
    The Journal of thoracic and cardiovascular surgery, 2002, Volume: 123, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Bronchi; Chemotherapy, Cancer, Regional Perfusion; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Hyperthermia, Induced; Infusions, Intravenous; Lung Neoplasms; Paclitaxel; Sheep; Treatment Outcome; Tumor Cells, Cultured

2002
A mouse model for the study of factors affecting angiogenesis.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Docetaxel; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Humans; Ifosfamide; Injections, Subcutaneous; Mice; Neovascularization, Pathologic; Paclitaxel; Prostheses and Implants; Surgical Sponges; Taxoids

2002
Polysaccharide of
    Pharmaceutical biology, 2020, Volume: 58, Issue:1

    Topics: Alzheimer Disease; Animals; Apoptosis; Cell Line; Cell Survival; Cognitive Dysfunction; Disease Models, Animal; Dose-Response Relationship, Drug; Galactose; Maze Learning; Mice; Mice, Inbred C57BL; Oxidative Stress; Polysaccharides; Taxus

2020
Anti-inflammatory activities of Taxusabietane A isolated from Taxus wallichiana Zucc.
    Fitoterapia, 2011, Volume: 82, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Edema; Female; Flavanones; Lipoxygenase Inhibitors; Male; Phenanthrenes; Phytotherapy; Plant Bark; Plant Extracts; Rats; Rats, Wistar; Taxus

2011
Control of hypertension in rats using volatile components of leaves of Taxus chinensis var. mairei.
    Journal of ethnopharmacology, 2012, May-07, Volume: 141, Issue:1

    Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Chromatography, Supercritical Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hydrochlorothiazide; Hypertension; Lipids; Male; Nitric Oxide; Nitroarginine; Phytotherapy; Plant Leaves; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Taxus; Time Factors; Volatilization

2012
Hypertonic sodium bicarbonate for Taxus media-induced cardiac toxicity in swine.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2002, Volume: 9, Issue:3

    Topics: Animals; Blood Pressure; Calcium; Disease Models, Animal; Electrocardiography; Heart Rate; Hydrogen-Ion Concentration; Hypertonic Solutions; Infusions, Intravenous; Male; Mannitol; Poisoning; Potassium; Sodium; Sodium Bicarbonate; Swine; Taxus

2002
Design and synthesis of novel anti-hyperalgesic agents based on 6-prenylnaringenin as the T-type calcium channel blockers.
    Bioorganic & medicinal chemistry, 2018, 08-15, Volume: 26, Issue:15

    Topics: Action Potentials; Analgesics; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; Drug Design; Flavonoids; HEK293 Cells; Humans; Inhibitory Concentration 50; Male; Mice; Neuralgia; Patch-Clamp Techniques; Structure-Activity Relationship

2018