paclitaxel has been researched along with Colorectal Neoplasms in 125 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (10.40) | 18.2507 |
| 2000's | 29 (23.20) | 29.6817 |
| 2010's | 56 (44.80) | 24.3611 |
| 2020's | 27 (21.60) | 2.80 |
| Authors | Studies |
|---|---|
| Kong, L; Li, Y; Liu, H; Liu, X; Wang, LL; Yuan, F; Zhang, L; Zhang, Y; Zuo, Z | 1 |
| Barros-Nepomuceno, FWA; de Souza, MVN; Lima, DJB; Maranhão, SS; Moura, AF; Nogueira, TCM; Oliveira, ACA; Paier, CRK; Pessoa, C; Pinheiro, AC | 1 |
| Cai, Z; Qi, C; Shang, A; Tian, J; Wang, W; Wu, L; Xuan, S; Yan, W | 1 |
| Babula, P; Chovancova, B; Kajsik, M; Krizanova, O; Liskova, V | 1 |
| Al Hassadi, Y; Aru, B; Erdogan, CS; Gemici, B; Yılmaz, B | 1 |
| Cai, S; Guo, S; Jin, Z; Shen, Y; Wang, Z; Yan, Y; Yang, L; Zeng, P | 1 |
| Chang, M; Hao, Y; Li, Z; Zhang, X | 1 |
| Duarte, D; Marques, L; Moura, C; Pereira, M; Santos, J; Vale, N | 1 |
| Im, CN; Kim, KS; Kim, SH; Kuh, HJ; Lee, MY; Na, K; Park, JK | 1 |
| Li, G; Mu, Y; Wang, J | 1 |
| Du, B; Liu, X; Luan, X; Zhang, W; Zhuang, C | 1 |
| Benhadji, KA; Fakih, MG; George, B; Ghidini, M; Makris, L; Shitara, K; Sundar, R; Taieb, J | 1 |
| Mandilaras, V; Park, CL; Rajadurai, CV; Ton Nu, TN | 1 |
| Emoto, S; Gohda, Y; Ishigami, H; Ishihara, S; Kashiwabara, K; Kitayama, J; Matsuzaki, H; Murono, K; Nozawa, H; Sasaki, K; Yamaguchi, H; Yokoyama, Y | 1 |
| Au, JLS; Chan, CHF; Lu, Z; Turaga, K; Wientjes, MG | 1 |
| Banerjee, UC; Chakrabarti, G; Das, A; Dastidar, DG; Datta, S; Ghosh, S; Pal, M; Thakur, NS | 1 |
| Hu, B; Liu, Y; Min, H; Wang, J; Xue, X | 1 |
| Aghanejad, A; Amini, M; Baghbani, E; Baradaran, B; Hejazi, M; Mokhtarzadeh, A; Mosafer, J; Rezaei, T | 1 |
| Lina, L; Qian, Z; Suoni, L; Wang, Y; Xu, L; Yang, Z; Zhou, J | 1 |
| Bai, Z; Ding, N; Guan, Q; Liu, X; Ma, L; Tong, B; Wei, Q; Zhang, W; Zhao, M | 1 |
| Feng, Y; Hu, L; Huang, Q; Li, L; Li, S; Liu, S; Shi, Q; Su, T; Tan, H; Tao, Z; Yang, H; Zhong, Y | 1 |
| Bastien, E; Canevat, A; Feron, O; Fourniols, T; Préat, V | 1 |
| Emoto, S; Ishihara, S; Ishimaru, K; Kaneko, M; Kawai, K; Muro, K; Murono, K; Nagata, H; Nozawa, H; Otani, K; Sasaki, K; Sonoda, H | 1 |
| Kim, JO; Le, TG; Nguyen, CN; Nguyen, HQ; Nguyen, VH; Phung, CD; Vu, TT; Yong, CS | 1 |
| Hu, J; Li, L; Li, R; Qian, X; Yang, M; Yu, L | 1 |
| Gao, M; Wang, K; Wang, X; Wang, Z; Xu, X; Zhang, H | 1 |
| Au, K; Battaglini, E; Geelan-Small, P; Goldstein, D; Grimison, P; Henderson, RD; Ke, H; Li, T; Marker, J; Mizrahi, D; Park, SB; Timmins, HC; Trinh, T; Wall, B; Wyld, D | 1 |
| Cheng, X; Huang, T; Li, F; Li, Q; Tang, Y; Tu, S; Wang, J; Zhang, B; Zhang, W; Zhou, C | 1 |
| Feng, J; Li, K; Shi, H; Zhang, X | 1 |
| He, L; Lei, Y; Lv, G; Wang, Y; Yan, C | 1 |
| Doki, Y; Eguchi, H; Fujii, A; Kitagawa, A; Kobayashi, Y; Kuramitsu, S; Masuda, T; Mimori, K; Mizushima, T; Mori, M; Noda, M; Otsu, H; Ozato, Y; Saito, H; Sato, K; Shimizu, D; Tobo, T | 1 |
| Hou, S; Liu, J; Song, J; Wang, J; Wang, Y; Zhang, C; Zhang, S; Zhao, Z | 1 |
| Chao, JI; Chen, C; Chen, TH; Cheng, HC; Li, LY; Liao, WS; Lin, J; Lin, YW; Liu, KK; Raj, EN; Wang, CC | 1 |
| Cai, S; Chan, K; Du, J; Li, Z; Lu, L; Ning, F; Qi, Y; Wang, H; Wang, Y; Wu, M | 1 |
| Ao, G; Cao, Y; Hao, Y; Hu, L; Hu, Z; Li, W; Sun, Y; Wang, Q; Wang, Y; Xu, G; Xu, J | 1 |
| Adam, L; Azad, N; Dasari, A; Eng, C; Fogelman, D; Karunasena, E; Kee, B; Kopetz, S; Morris, J; Overman, MJ; Pisanic, TR; Raghav, K; Shroff, R; Vilar, E; Wang, J; Wolff, R | 1 |
| Brunner, AL; Cain, J; Cancilla, B; Cattaruzza, F; Evans, JW; Fischer, MM; Hoey, T; Hussein, R; Kapoun, A; Murriel, C; O'Young, G; Wang, M; Yen, WC; Yeung, VP | 1 |
| Barrios, P; Cascales-Campos, P; Esteve-Pérez, N; Morales-Soriano, R; Segura-Sampedro, JJ | 1 |
| Akin, S; Kas Guner, C | 1 |
| Kennedy, P; Pereira, I; Sarmento, B; Sousa, F | 1 |
| Luo, R; Qiu, C; Sheng, L; Wang, L; Zhang, X | 1 |
| Lei, CJ; Li, L; Liu, JN; Mei, J; Yuan, LL | 1 |
| Dudenkova, VV; Lukina, MM; Shimolina, LE; Shirmanova, MV; Snopova, LB; Zagaynova, EV | 1 |
| Emoto, S; Hata, K; Hiyoshi, M; Ishihara, S; Ishimaru, K; Kaneko, M; Kawai, K; Muro, K; Murono, K; Nagata, H; Nishikawa, T; Nozawa, H; Otani, K; Sasaki, K; Shuno, Y; Tanaka, T | 1 |
| Hou, Y; Li, D; Pan, Y; Wang, G; Wang, T; Xue, Y; Yao, A; Zhao, J; Zhao, S | 1 |
| Akyol, A; Güner, G; Gürdal, H; Işik, A; Karabulut, E; Öztop, S; Yilmaz, E | 1 |
| Du, H; Du, RL; Jia, YF; Li, SZ; Song, XM; Tu, R; Zhang, Q; Zhang, XD; Zhang, ZY; Zheng, Z | 1 |
| Camps, J; Dalton, S; Li, Y; Lyon, K; Ried, T; Tang, J; Zhao, S | 1 |
| Kim, YJ; Kuh, HJ; Lee, J; Lee, SH | 1 |
| Barber, CL; Daenen, LG; He, H; Hofmann, JJ; Iruela-Arispe, ML; Lane, TF; Monvoisin, A; Radtke, F; Roodhart, JM; van Amersfoort, M; Voest, EE | 1 |
| Bai, F; Ban, FQ; Chen, HZ; Fang, C; Guan, YY; Liu, YR; Lu, Q; Luan, X; Wang, C; Yu, DH; Zhao, M | 1 |
| Al-Azzam, SI; Alsaad, AA; Alzoubi, KH; Mhaidat, NM | 1 |
| Cai, H; Dong, Z; Feng, ST; Li, J; Li, ZP; Luo, Y; Shuai, X; Wang, Y; Yin, T | 1 |
| Feng, LS; He, YX; Li, L | 1 |
| Ding, Z; Jiang, P; Li, G; Tang, J; Tang, Z; Wu, H; Xu, F | 1 |
| Ba, Y; Chen, Y; Deng, T; He, Y; Li, W; Liu, R; Ren, L; Wang, X; Ying, G; Zhou, L; Zuo, D | 1 |
| Mei, X; Xie, X; Yang, Y; Zhang, H | 1 |
| Cai, Y; Cao, L; Chen, C; Chen, S; Jiang, Y; Lu, N; Xu, J; Yin, Y; Zhang, C | 1 |
| Chen, MB; Fu, XL; Lu, PH; Tian, Y; Yang, L; Zhang, Y; Zhu, YQ | 1 |
| Braet, F; Gloria, D; Su, Y; Thordarson, P; Truong, WT | 1 |
| Januchowski, R; Nowicki, M; Wojtowicz, K; Zabel, M | 1 |
| Fang, XD; Fei, BY; Wang, XY | 1 |
| Ahn, C; Han, GY; Kim, B; Kim, CW; Kim, MJ; Koo, JE; Lee, YS | 1 |
| Li, H; Lu, F; Wang, A; Zhang, Z; Zhi, H | 1 |
| Chera, B; Deal, AM; Gilbert, J; Grilley Olson, J; Hayes, DN; Murphy, BA; Weiss, J; Weissler, M | 1 |
| Chen, X; Fang, X; Gao, S; Liu, M; Liu, Y; Mao, C | 1 |
| Wu, AW; Xie, BY | 1 |
| Adenis, A; Bennouna, J; Conroy, T; Ducreux, M; Jeanes, J; Li, L; Lièvre, A; Portales, F; Romano, A | 1 |
| Al Rihani, SB; Ambudkar, SV; Chen, ZS; Gupta, P; Kaddoumi, A; Shi, Z; Shukla, S; Wang, YJ; Wei, MN; Zhang, GN; Zhang, XY; Zhang, YK | 1 |
| Abaza, MS; Al-Attiyah, RJ; Bahman, AM | 1 |
| Cao, X; Garofalo, A; Grande, F; Louie, S; Neamati, N; Oshima, T; Yamada, R | 1 |
| Akasaka, K; Akinaga, S; Honda, S; Ichikawa, S; Iida, S; Ishida, H; Kusaka, H; Murakata, C; Nakai, R; Nitta, M; Okamoto, S; Saya, H; Takada, C; Takahashi, T; Tsujita, T; Yamashita, Y | 1 |
| Al-Sawalha, NA; Alali, FQ; Jaradat, SA; Matalka, II; Matalqah, SM; Mhaidat, NM; Thorne, RF | 1 |
| Arpicco, S; Brusa, P; Cattel, L; Dosio, F; Stella, B | 1 |
| Belmont, LD; Davis, DP; Forrest, WF; Jackson, PK; Lee, J; Lei, XC; Peterson, D | 1 |
| Matouskova, E; Mladkova, J; Sanda, M; Selicharova, I | 1 |
| Bergin, P; Damianovich, D; Findlay, M; Hanning, F; Hill, A; McKeage, MJ; Thompson, P | 1 |
| Choi, MS; Kim, SH; Kuh, HJ | 1 |
| Bouquet, W; Ceelen, WP; De Smet, L; De Vos, F; Debergh, I; Deleye, S; Remon, JP; Staelens, S; Van Damme, N; Vervaet, C | 1 |
| Iwasaki, H; Katano, M; Kumagai, M; Mibu, R; Nakano, K; Onishi, H; Suzuki, H; Wakabayashi, R; Xu, R; Yamasaki, A | 1 |
| Arends, J; Büchert, M; Fasol, U; Fiedler, U; Frost, A; Mross, K; Scharr, D; Scheuenpflug, J | 1 |
| Gong, W; Lu, X; Min, P; Song, Q; Yi, X; Zhao, J | 1 |
| Bellot, GL; Koh, D; Tan, WH; Tay, LL; Wang, X | 1 |
| Kuh, HJ; Lee, J; Lee, JH; Na, K; Song, SC | 1 |
| Chae, SY; Jang, YL; Jeong, JH; Kim, HT; Kim, MG; Kim, SH; Lee, K; Lee, MS; Lim, DW; Son, S; Yun, UJ | 1 |
| Cho, MJ; Guley, PC; Hackett, MJ; Hartranft, ME; Joolakanti, S | 1 |
| Bepler, G; Chen, W; Ghosh, D; Norkin, M; Raghunathan, TE; Sargent, DJ | 1 |
| Agúndez, JA; García-Gamito, FJ; García-Martín, E; Martínez, C; Pizarro, RM | 1 |
| Brierre, JE; Buller, EJ; Cole, JL; Fontenot, MF; Lormand, NA; Rainey, JM; Rinaldi, DA; Stagg, MP | 1 |
| Capozzoli, MJ; Egorin, MJ; Hershberger, PA; Johnson, CS; Muindi, JR; Peng, Y; Potter, DM; Tauch, JS; Trump, DL | 1 |
| Gotoh, M; Katsu, K; Kawabe, S; Ohta, S; Takiuchi, H | 1 |
| Hirai, K; Kawahara, S; Ushigome, T | 1 |
| Langer, CJ | 1 |
| Du, W; Posner, M; Schmidt, H; Shafaee, Z; Weichselbaum, R | 1 |
| Koziara, JM; Mumper, RJ; Tseng, MT; Whisman, TR | 1 |
| Downward, J; Swanton, C; Tomlinson, I | 1 |
| Agúndez, JA; García-Martín, E; Gutierrez-Martín, Y; Jover, R; Martínez, C; Pérez, G; Pizarro, RM | 1 |
| Martin, SG; Mukherjee, A | 1 |
| Broemeling, L; Gong, J; Humphreys, R; Kohanim, S; Kurzrock, R; Yang, D | 1 |
| Bensussan, A; Bizzini, B; Gallo, RC; Genne, P; Larcier, P; Le Buanec, H; Paturance, S; Rad, FH; Ryffel, B; Uzan, G; Zagury, D | 1 |
| Berg, D; Bernard, S; Brescia, F; Cohn, A; Frenette, G; Hochster, H; Lockhart, AC; Macdonald, J; Melin, S; Picus, J; Raftopoulos, H; Ramanathan, RK | 1 |
| Hirata, K; Hiyama, S; Inui, N; Kimura, H; Kimura, Y; Shirasaka, T; Yamada, Y; Yamamitsu, S | 1 |
| Bruntsch, V; Dirix, LY; Franklin, H; Kaye, SB; Le Bail, N; Pavlidis, NA; Smyth, JF; Sternberg, CN; ten Bokkel Huinink, WW; Wanders, S | 1 |
| Abbruzzese, JL; Ajani, JA; Bready, B; Lassere, Y; Levin, B; Patt, Y; Pazdur, R; Soh, LT; Soo, E; Sugarman, S | 1 |
| Rozhin, J; Sameni, M; Sloane, BF; Ziegler, G | 1 |
| Rougier, P | 1 |
| Markman, M | 1 |
| Aebi, S; Fink, D; Haas, M; Howell, SB; Kim, HK; Nebel, S; Norris, PS | 1 |
| Andre, AM; Clark, TB; Conti, JA; Huang, Y; Kemeny, NE; Stockman, J | 1 |
| Aebi, S; Fink, D; Fink, JL; Gordon, R; Howell, SB; Kim, HK; Zheng, H | 1 |
| Ajani, JA; Dumas, P; Fairweather, J; Pazdur, R | 1 |
| Bonner, HS; Haller, DG; Huang, K; Recio, A; Shaw, LM; Vaughn, DJ | 1 |
| Chen, Z; Gu, WZ; Ng, SC; Rosenberg, SH; Tahir, SK | 1 |
| Boisdron-Celle, M; Boulanger, N; Gamelin, E | 1 |
| Bakker, PJ; Franken, NA; Haveman, J; Savonije, JH; van Bree, C | 1 |
| Kobayashi, T; Maeda, Y; Okamoto, R; Omuro, Y; Sasaki, T; Takeda, N | 1 |
| Balcer-Kubiczek, EK; Harrison, GH; Kennedy, AS; Mansfield, CM; Xu, JF; Zhou, XJ | 1 |
| Ahmed, MM; Alcock, RA; Chendil, D; Gallicchio, VS; Mayhew, C; Mohiuddin, M; Oakes, R; Patel, N | 1 |
| Blesch, K; Reigner, B; Weidekamm, E | 1 |
| Prescott, LM | 1 |
| Carpini, RD; Fedier, A; Fink, D; Haller, U; Schwarz, VA; Walt, H | 1 |
| Horowitz, J | 1 |
| Aiba, K; Akaza, H; Blackledge, G; Boku, N; Ikeda, T; Isonishi, S; Kato, M; Kawai, K; Mikami, O; Ohashi, Y; Saeki, T; Saijo, N; Sone, S; Stribling, D; Tsukagoshi, S; Tsuruo, T | 1 |
| Sun, Y | 1 |
| Ambrož, M; Boušová, I; Lněničková, K; Matoušková, P; Skálová, L | 1 |
8 review(s) available for paclitaxel and Colorectal Neoplasms
| Article | Year |
|---|---|
An Unconventional Regimen of Carboplatin and Paclitaxel in Metastatic Colorectal Carcinosarcoma: A Case Report and Review of Literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinosarcoma; Colorectal Neoplasms; Female; Humans; Paclitaxel | 2023 |
CT-2103: emerging utility and therapy for solid tumours.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Colorectal Neoplasms; Female; Humans; Neoplasms; Ovarian Neoplasms; Paclitaxel; Polyglutamic Acid; Taxoids | 2004 |
Chromosomal instability, colorectal cancer and taxane resistance.
Topics: Antineoplastic Agents; Aurora Kinase A; Aurora Kinases; Chromosomal Instability; Clinical Trials as Topic; Colorectal Neoplasms; Drug Resistance, Neoplasm; Humans; Microtubules; Mitosis; Neoplasm Metastasis; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; Spindle Apparatus; Taxoids; Vincristine | 2006 |
Docetaxel delivers new management opportunities for gastrointestinal carcinomas.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Docetaxel; Female; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Multicenter Studies as Topic; Neoplasm Metastasis; Paclitaxel; Pancreatic Neoplasms; Stomach Neoplasms; Taxoids | 1995 |
[Pharmacokinetic monitoring].
Topics: Antineoplastic Agents; Body Mass Index; Camptothecin; Colorectal Neoplasms; Drug Interactions; Drug Monitoring; Etoposide; Fluorouracil; Humans; Irinotecan; Liver; Paclitaxel; Topotecan | 2000 |
[New combination therapies for gastrointestinal cancer].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colorectal Neoplasms; Docetaxel; Fluorouracil; Humans; Irinotecan; Leucovorin; Paclitaxel; Prognosis; Stomach Neoplasms; Survival Analysis; Taxoids | 2000 |
Clinical pharmacokinetics of capecitabine.
Topics: Antacids; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Docetaxel; Dose-Response Relationship, Drug; Drug Interactions; Fluorouracil; Food; Humans; Intestinal Absorption; Leucovorin; Liver Diseases; Paclitaxel; Protein Binding; Taxoids | 2001 |
Adenovirus-mediated p53 gene therapy: overview of preclinical studies and potential clinical applications.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Combined Modality Therapy; Drug Resistance, Neoplasm; Female; Genes, p53; Genetic Therapy; Genetic Vectors; Glioblastoma; Head and Neck Neoplasms; Humans; Injections; Interleukin-2; Liver Neoplasms; Lung Neoplasms; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Neoplasms; Ovarian Neoplasms; Paclitaxel; Radiotherapy, Adjuvant; Recombinant Fusion Proteins; Salvage Therapy; Signal Transduction; Treatment Outcome; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 1999 |
15 trial(s) available for paclitaxel and Colorectal Neoplasms
| Article | Year |
|---|---|
Effects of prior therapies on outcomes with trifluridine/tipiracil in patients with metastatic gastric/gastroesophageal junction cancer in a randomized phase III trial (TAGS).
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Esophagogastric Junction; Humans; Irinotecan; Paclitaxel; Pyrrolidines; Stomach Neoplasms; Trifluridine | 2023 |
Intraperitoneal paclitaxel combined with FOLFOX/CAPOX plus bevacizumab for colorectal cancer with peritoneal carcinomatosis (the iPac-02 trial): study protocol of a single arm, multicenter, phase 2 study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Humans; Multicenter Studies as Topic; Paclitaxel; Peritoneal Neoplasms | 2023 |
Phase II study of nab-paclitaxel in refractory small bowel adenocarcinoma and CpG island methylator phenotype (CIMP)-high colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Albumins; Animals; Cell Cycle Proteins; Colorectal Neoplasms; CpG Islands; DNA Methylation; DNA Mutational Analysis; Female; Humans; Intestine, Small; Male; Mice, Inbred NOD; Mice, SCID; Middle Aged; Neoplasm Proteins; Paclitaxel; Phenotype; Poly-ADP-Ribose Binding Proteins; Promoter Regions, Genetic; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays | 2018 |
Safety of intraperitoneal paclitaxel combined with conventional chemotherapy for colorectal cancer with peritoneal carcinomatosis: a phase I trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Middle Aged; Oxaliplatin; Paclitaxel; Patient Safety; Peritoneal Neoplasms; Prognosis; Young Adult | 2019 |
Using the galactose-α-1,3-galactose enzyme-linked immunosorbent assay to predict anaphylaxis in response to cetuximab.
Topics: Albumins; Anaphylaxis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cetuximab; Colorectal Neoplasms; Disaccharides; Enzyme-Linked Immunosorbent Assay; Head and Neck Neoplasms; Humans; Immunoglobulin E; Paclitaxel; Predictive Value of Tests; Prospective Studies; Smoking; Southeastern United States | 2016 |
Efficacy and safety of nab-paclitaxel in patients with previously treated metastatic colorectal cancer: a phase II COLO-001 trial.
Topics: Albumins; Colorectal Neoplasms; Female; Genes, ras; Humans; Male; Middle Aged; Mutation; Neoplasm Metastasis; Paclitaxel | 2017 |
Vascular and pharmacokinetic effects of EndoTAG-1 in patients with advanced cancer and liver metastasis.
Topics: Adult; Aged; Angiogenesis Inhibitors; Angiotensin II; Area Under Curve; Breast Neoplasms; Colorectal Neoplasms; Contrast Media; Endothelin-1; Female; Humans; Interleukins; Liposomes; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Paclitaxel; Pancreatic Neoplasms; Ultrasonography; Vascular Endothelial Growth Factor A | 2012 |
Phase I trial of gemcitabine, administered as a standard and constant dose-rate infusion, in combination with paclitaxel in patients with advanced solid tumors (LOA-2).
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Paclitaxel; Urologic Neoplasms | 2002 |
Pharmacokinetics of high-dose oral calcitriol: results from a phase 1 trial of calcitriol and paclitaxel.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Calcitriol; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Prostatic Neoplasms; Radioimmunoassay | 2002 |
[Paclitaxel for treatment of colorectal cancer].
Topics: Aged; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Treatment Outcome | 2003 |
A phase II study of milataxel: a novel taxane analogue in previously treated patients with advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Blood Cell Count; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Male; Middle Aged; Paclitaxel; Treatment Failure | 2008 |
Docetaxel (Taxotere), a novel taxoid, in the treatment of advanced colorectal carcinoma: an EORTC Early Clinical Trials Group Study.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Docetaxel; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Paclitaxel; Taxoids | 1994 |
Phase II trial of docetaxel (Taxotere) in metastatic colorectal carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Agranulocytosis; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Docetaxel; Drug Administration Schedule; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Paclitaxel; Taxoids | 1994 |
Phase II trial of docetaxel (Taxotere) for untreated advanced colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Docetaxel; Female; Humans; Male; Middle Aged; Paclitaxel; Taxoids | 1998 |
A phase II trial and pharmacokinetic analysis of 96-hour infusional paclitaxel in patients with metastatic colorectal cancer.
Topics: Aged; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Metastasis; Neutropenia; Paclitaxel | 1998 |
102 other study(ies) available for paclitaxel and Colorectal Neoplasms
| Article | Year |
|---|---|
Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Artemisinins; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Female; HCT116 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Tumor Cells, Cultured | 2019 |
Synthesis of PJOV56, a new quinoxalinyl-hydrazone derivative able to induce autophagy and apoptosis in colorectal cancer cells, and related compounds.
Topics: Apoptosis; Autophagy; Colorectal Neoplasms; Humans; Hydrazones; Quinoxalines; Structure-Activity Relationship | 2020 |
Combination therapy with Nab-paclitaxel and the interleukin-15 fused with anti-human serum albumin nanobody as a synergistic treatment for colorectal cancer.
Topics: Albumins; Animals; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; HCT116 Cells; Humans; Interleukin-15; Mice; Paclitaxel; Single-Domain Antibodies; Xenograft Model Antitumor Assays | 2022 |
Slow sulfide donor GYY4137 potentiates effect of paclitaxel on colorectal carcinoma cells.
Topics: Adenosine Triphosphate; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Humans; Hydrogen Sulfide; Morpholines; Organothiophosphorus Compounds; Paclitaxel; Sulfides | 2022 |
Combinatorial effects of melatonin and paclitaxel differ depending on the treatment scheme in colorectal cancer in vitro.
Topics: Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Humans; Melatonin; Paclitaxel; TOR Serine-Threonine Kinases | 2022 |
Structural optimization and in vivo evaluation of a colorectal stent with anti-migration and anti-tumor properties.
Topics: Alloys; Animals; Colorectal Neoplasms; Paclitaxel; Rabbits; Stents | 2022 |
Effects of Salidroside Combined with Paclitaxel on Proliferation, Migration, and Epithelial Mesenchyme of Colorectal Cancer Cells.
Topics: Cell Proliferation; Colorectal Neoplasms; Humans; Mesoderm; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2022 |
Prediction of Drug Synergism between Peptides and Antineoplastic Drugs Paclitaxel, 5-Fluorouracil, and Doxorubicin Using In Silico Approaches.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colorectal Neoplasms; Doxorubicin; Drug Synergism; Fluorouracil; Humans; Paclitaxel; Peptides | 2022 |
Effect of paclitaxel priming on doxorubicin penetration in a multicellular layer model of human colorectal cancer cells.
Topics: Cell Line, Tumor; Colorectal Neoplasms; Doxorubicin; Fibronectins; HT29 Cells; Humans; Paclitaxel | 2023 |
Sphingosine kinase-2 silencing modulates sensitivity of HT-29 human colorectal cancer cells to paclitaxel-induced cell death through altering apoptosis-related proteins.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Paclitaxel; RNA, Small Interfering; Survivin | 2023 |
Structure optimization of an F-indole-chalcone (FC116) on 4-methoxyphenyl group and therapeutic potential against colorectal cancers with low cytotoxicity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Colorectal Neoplasms; Indoles; Mice; Molecular Structure; Paclitaxel; Structure-Activity Relationship | 2023 |
Surgical management of peritoneal metastasis: Opportunities for pharmaceutical research.
Topics: Antineoplastic Combined Chemotherapy Protocols; Ascites; Colorectal Neoplasms; Combined Modality Therapy; Humans; Hyperthermia, Induced; Paclitaxel; Peritoneal Neoplasms; Pharmaceutical Preparations; Pharmaceutical Research; Proteomics; Tandem Mass Spectrometry | 2023 |
Paclitaxel-encapsulated core-shell nanoparticle of cetyl alcohol for active targeted delivery through oral route.
Topics: A549 Cells; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Fatty Alcohols; Flow Cytometry; Humans; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Spheroids, Cellular | 2019 |
Guanylate-binding protein-2 inhibits colorectal cancer cell growth and increases the sensitivity to paclitaxel of paclitaxel-resistant colorectal cancer cells by interfering Wnt signaling.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Humans; Paclitaxel; Tumor Cells, Cultured; Wnt Signaling Pathway | 2020 |
MicroRNA-193a and taxol combination: A new strategy for treatment of colorectal cancer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Colorectal Neoplasms; Combined Modality Therapy; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Paclitaxel; Tumor Cells, Cultured | 2020 |
Arctigenin enhances the sensitivity of cisplatin resistant colorectal cancer cell by activating autophagy.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Autophagy; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cisplatin; Colorectal Neoplasms; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Furans; Humans; Inhibitory Concentration 50; Lignans; Oxaliplatin; Paclitaxel; Up-Regulation | 2019 |
5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; DNA; DNA Damage; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; G2 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; Imidazoles; Lung Neoplasms; Paclitaxel; Tubulin | 2020 |
Co-Administration Of iRGD Enhances Tumor-Targeted Delivery And Anti-Tumor Effects Of Paclitaxel-Loaded PLGA Nanoparticles For Colorectal Cancer Treatment.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Drug Delivery Systems; Humans; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasm Invasiveness; Oligopeptides; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Spheroids, Cellular; Tissue Distribution | 2019 |
Inhibition of colorectal cancer-associated fibroblasts by lipid nanocapsules loaded with acriflavine or paclitaxel.
Topics: Acriflavine; Antineoplastic Agents; Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Colorectal Neoplasms; Drug Carriers; HCT116 Cells; Humans; Lipids; Nanocapsules; Paclitaxel; Tumor Microenvironment | 2020 |
Efficacy of intraperitoneally administered paclitaxel for colorectal cancer with peritoneal metastases.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Humans; Oxaliplatin; Paclitaxel; Peritoneal Neoplasms | 2020 |
PEGylated-Paclitaxel and Dihydroartemisinin Nanoparticles for Simultaneously Delivering Paclitaxel and Dihydroartemisinin to Colorectal Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Artemisinins; Cell Membrane Permeability; Colorectal Neoplasms; Drug Compounding; Drug Liberation; Fluorescent Dyes; Gene Expression Regulation; HT29 Cells; Humans; Mice, Inbred BALB C; Mice, Nude; Nanocapsules; Optical Imaging; Paclitaxel; Polyethylene Glycols; Proto-Oncogene Proteins c-bcl-2; Tissue Distribution | 2020 |
iRGD Co-Administration with Paclitaxel-Loaded PLGA Nanoparticles Enhance Targeting and Antitumor Effect in Colorectal Cancer Treatment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Drug Carriers; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Oligopeptides; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Tumor Cells, Cultured | 2021 |
Metabolomics analysis of multidrug resistance in colorectal cancer cell and multidrug resistance reversal effect of verapamil.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers; Cell Line, Tumor; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Metabolome; Metabolomics; Paclitaxel; Tandem Mass Spectrometry; Verapamil | 2021 |
Hemoglobin, Body Mass Index, and Age as Risk Factors for Paclitaxel- and Oxaliplatin-Induced Peripheral Neuropathy.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anemia; Antineoplastic Agents; Body Mass Index; Breast Neoplasms; Colorectal Neoplasms; Female; Hemoglobins; Humans; Male; Middle Aged; Neurotoxicity Syndromes; Obesity; Overweight; Oxaliplatin; Paclitaxel; Peripheral Nervous System Diseases; Risk Factors; Severity of Illness Index; Sex Factors; Young Adult | 2021 |
Utidelone inhibits growth of colorectal cancer cells through ROS/JNK signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Death; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Epothilones; Humans; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mice, Nude; Paclitaxel; Reactive Oxygen Species | 2021 |
Overexpression of long non-coding RNA urothelial carcinoma associated 1 causes paclitaxel (Taxol) resistance in colorectal cancer cells by promoting glycolysis.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Resistance, Neoplasm; Glycolysis; Hexokinase; Humans; L-Lactate Dehydrogenase; Paclitaxel; RNA, Long Noncoding | 2021 |
PERK activation by CCT020312 chemosensitizes colorectal cancer through inducing apoptosis regulated by ER stress.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Drug Synergism; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; G2 Phase Cell Cycle Checkpoints; Gene Knockdown Techniques; Heat-Shock Proteins; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Paclitaxel; Phosphorylation; Signal Transduction; Transcription Factor CHOP; Xenograft Model Antitumor Assays | 2021 |
Mitotic checkpoint regulator RAE1 promotes tumor growth in colorectal cancer.
Topics: Aged; Animals; Caco-2 Cells; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Databases, Genetic; Drug Resistance, Neoplasm; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Middle Aged; Nuclear Matrix-Associated Proteins; Nucleocytoplasmic Transport Proteins; Paclitaxel; Prognosis; Up-Regulation | 2021 |
Kanglaite sensitizes colorectal cancer cells to Taxol via NF-κΒ inhibition and connexin 43 upregulation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colorectal Neoplasms; Connexin 43; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Mice, Inbred BALB C; NF-kappa B; Paclitaxel; Treatment Outcome; Up-Regulation | 2017 |
Co-delivery of paclitaxel and cetuximab by nanodiamond enhances mitotic catastrophe and tumor inhibition.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cetuximab; Colorectal Neoplasms; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; ErbB Receptors; Gene Expression; Humans; Mitosis; Nanodiamonds; Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays | 2017 |
Participation of CCL1 in Snail-Positive Fibroblasts in Colorectal Cancer Contribute to 5-Fluorouracil/Paclitaxel Chemoresistance.
Topics: 3T3 Cells; Animals; Cancer-Associated Fibroblasts; Cell Line, Tumor; Chemokine CCL1; Coculture Techniques; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Humans; Mice; Neoplasm Transplantation; NF-kappa B; Paclitaxel; Signal Transduction; Snail Family Transcription Factors; Transforming Growth Factor beta | 2018 |
YAP transcriptionally regulates COX-2 expression and GCCSysm-4 (G-4), a dual YAP/COX-2 inhibitor, overcomes drug resistance in colorectal cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Binding Sites; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Genes, Reporter; Humans; Male; Mice; Nuclear Proteins; Paclitaxel; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Transport; Response Elements; Transcription Factors; Transcriptional Activation; Xenograft Model Antitumor Assays | 2017 |
RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations.
Topics: Animals; Bridged-Ring Compounds; Colorectal Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Neoplasm Proteins; Paclitaxel; Taxoids; Thrombospondins; Tumor Microenvironment; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2017 |
Current practice in cytoreductive surgery and HIPEC for metastatic peritoneal disease: Spanish multicentric survey.
Topics: Antineoplastic Agents; Carcinoma; Cardiac Output; Cisplatin; Colorectal Neoplasms; Cytoreduction Surgical Procedures; Female; Humans; Hyperthermia, Induced; Infusions, Parenteral; Male; Mesothelioma; Mitomycin; Monitoring, Intraoperative; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Paclitaxel; Peritoneal Neoplasms; Practice Patterns, Physicians'; Spain; Stomach Neoplasms; Surveys and Questionnaires | 2018 |
Investigation of the relationship among fatigue, self-efficacy and quality of life during chemotherapy in patients with breast, lung or gastrointestinal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colorectal Neoplasms; Fatigue; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Leucovorin; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Paclitaxel; Quality of Life; Self Care; Self Efficacy; Surveys and Questionnaires; Turkey | 2019 |
Carcinoembryonic antigen-targeted nanoparticles potentiate the delivery of anticancer drugs to colorectal cancer cells.
Topics: Antibodies, Monoclonal; Carcinoembryonic Antigen; Cell Survival; Colorectal Neoplasms; Drug Carriers; Drug Compounding; Drug Liberation; Humans; Nanomedicine; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglactin 910; Solubility; Surface Properties; Technology, Pharmaceutical; Tubulin Modulators | 2018 |
LINC00473 promotes the Taxol resistance via miR-15a in colorectal cancer.
Topics: Apoptosis; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; MicroRNAs; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; RNA, Long Noncoding | 2018 |
Down-regulation of miR-29a facilitates apoptosis of colorectal carcinoma cell SW480 and suppresses its Paclitaxel resistance.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; HEK293 Cells; Humans; MicroRNAs; Paclitaxel; PTEN Phosphohydrolase | 2018 |
In vivo metabolic and SHG imaging for monitoring of tumor response to chemotherapy.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor; Cisplatin; Collagen; Colorectal Neoplasms; Disease Models, Animal; Female; Irinotecan; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence, Multiphoton; NADP; Paclitaxel; Second Harmonic Generation Microscopy | 2019 |
Toll-like receptor 3 agonist poly I:C reinforces the potency of cytotoxic chemotherapy via the TLR3-UNC93B1-IFN-β signaling axis in paclitaxel-resistant colon cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Interferon-beta; Membrane Transport Proteins; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Poly I-C; Signal Transduction; Toll-Like Receptor 3; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
Class III β-tubulin Expression in Colorectal Neoplasms Is a Potential Predictive Biomarker for Paclitaxel Response.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Silencing; HCT116 Cells; Humans; Immunohistochemistry; Oligonucleotide Array Sequence Analysis; Paclitaxel; RNA, Small Interfering; Tubulin | 2019 |
DUB3 deubiquitinates and stabilizes NRF2 in chemotherapy resistance of colorectal cancer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Colorectal Neoplasms; CRISPR-Cas Systems; Deubiquitinating Enzymes; Drug Resistance, Neoplasm; Endopeptidases; HCT116 Cells; HEK293 Cells; HT29 Cells; Humans; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Paclitaxel; Transcriptional Activation; Ubiquitination | 2019 |
Cancer driver-passenger distinction via sporadic human and dog cancer comparison: a proof-of-principle study with colorectal cancer.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Cell Polarity; Cell Proliferation; Colorectal Neoplasms; Dogs; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Genome-Wide Association Study; Guanine Nucleotide Exchange Factors; HCT116 Cells; Humans; Molecular Sequence Annotation; Paclitaxel; Pilot Projects; rab GTP-Binding Proteins; Receptors, Cytoplasmic and Nuclear | 2014 |
Non-nuclear localization of Ki-67 in human colorectal cancer cells grown as multicellular layers.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Culture Techniques; Cell Cycle; Cell Membrane; Cell Nucleus; Cell Proliferation; Colorectal Neoplasms; Cytoplasm; Doxorubicin; Female; HT29 Cells; Humans; Ki-67 Antigen; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Models, Biological; Paclitaxel; Spheroids, Cellular; Xenograft Model Antitumor Assays | 2013 |
Notch1 regulates angio-supportive bone marrow-derived cells in mice: relevance to chemoresistance.
Topics: Animals; Antigens, CD; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bone Marrow Cells; Cadherins; Carcinoma, Lewis Lung; Cisplatin; Colorectal Neoplasms; Drug Resistance, Neoplasm; Mammary Neoplasms, Animal; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Paclitaxel; Receptor, Notch1; Xenograft Model Antitumor Assays | 2013 |
Nanoparticle-mediated drug delivery to tumor neovasculature to combat P-gp expressing multidrug resistant cancer.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Colon; Colorectal Neoplasms; Drug Delivery Systems; Drug Resistance, Neoplasm; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Peptides; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Caffeine inhibits paclitaxel‑induced apoptosis in colorectal cancer cells through the upregulation of Mcl‑1 levels.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Butadienes; Caffeine; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Endoplasmic Reticulum Chaperone BiP; Extracellular Signal-Regulated MAP Kinases; Heat-Shock Proteins; Humans; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Nitriles; Paclitaxel; Signal Transduction; Up-Regulation | 2014 |
pH-sensitive nanomicelles for controlled and efficient drug delivery to human colorectal carcinoma LoVo cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Drug Carriers; Ferric Compounds; Humans; Intracellular Space; Materials Testing; Mice; Micelles; Nanoparticles; Paclitaxel; Particle Size; Polymers | 2014 |
Cytotoxic triterpenesaponins from Ilex pubescens.
Topics: Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; HCT116 Cells; HT29 Cells; Humans; Ilex; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Paclitaxel; Plant Roots; Saponins; Triterpenes | 2014 |
Knockdown of Akt2 expression by shRNA inhibits proliferation, enhances apoptosis, and increases chemosensitivity to paclitaxel in human colorectal cancer cells.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HCT116 Cells; Humans; Multidrug Resistance-Associated Proteins; Paclitaxel; Proto-Oncogene Proteins c-akt; RNA, Small Interfering | 2015 |
Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Blotting, Western; Camptothecin; Case-Control Studies; Cell Proliferation; Cisplatin; Colorectal Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Female; Flow Cytometry; Fluorescent Antibody Technique; Fluorouracil; Humans; Immunoenzyme Techniques; Irinotecan; Male; Matrix Metalloproteinase 7; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Syndecan-1; Tumor Cells, Cultured | 2014 |
Photo-responsive and NGR-mediated multifunctional nanostructured lipid carrier for tumor-specific therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Cell-Penetrating Peptides; Chemistry, Pharmaceutical; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Carriers; Drug Stability; Female; Half-Life; Humans; Infrared Rays; Injections, Intravenous; Lipids; Male; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Nanotechnology; Oligopeptides; Paclitaxel; Particle Size; Photons; Rats, Sprague-Dawley; Solubility; Technology, Pharmaceutical; Xenograft Model Antitumor Assays | 2015 |
ING4 enhances paclitaxel's effect on colorectal cancer growth in vitro and in vivo.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Colorectal Neoplasms; Genetic Therapy; Genetic Vectors; Homeodomain Proteins; Humans; Immunohistochemistry; Mice; Mice, Nude; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2015 |
MicroRNA-101 down-regulates sphingosine kinase 1 in colorectal cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Base Sequence; Cell Division; Colorectal Neoplasms; DNA Primers; Down-Regulation; HT29 Cells; Humans; Mice; Mice, SCID; MicroRNAs; Paclitaxel; Phosphotransferases (Alcohol Group Acceptor); Real-Time Polymerase Chain Reaction | 2015 |
Dissolution and degradation of Fmoc-diphenylalanine self-assembled gels results in necrosis at high concentrations in vitro.
Topics: Animals; Cell Survival; Colorectal Neoplasms; Dipeptides; Fluorenes; Fluorouracil; Humans; Hydrogels; Molecular Structure; Paclitaxel; Peptides; Phenylalanine; Solubility | 2015 |
Inhibition of protein glycosylation reverses the MDR phenotype of cancer cell lines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Colorectal Neoplasms; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Glycosylation; Humans; Ovarian Neoplasms; Paclitaxel; Phenotype; Topotecan; Tunicamycin | 2015 |
MicroRNA-143 replenishment re-sensitizes colorectal cancer cells harboring mutant, but not wild-type, KRAS to paclitaxel treatment.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Genes, ras; Humans; MicroRNAs; Mutation; Neoplasm Proteins; Oncogene Protein p21(ras); Paclitaxel; RNA; Transfection | 2016 |
Dual-Blocking of PI3K and mTOR Improves Chemotherapeutic Effects on SW620 Human Colorectal Cancer Stem Cells by Inducing Differentiation.
Topics: AC133 Antigen; Animals; Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cell Survival; Chromones; Colorectal Neoplasms; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Morpholines; Neoplastic Stem Cells; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolines; Signal Transduction; Sirolimus; SOXB1 Transcription Factors; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2016 |
RETRACTED: STAT3-dependent TXNDC17 expression mediates Taxol resistance through inducing autophagy in human colorectal cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Autophagy; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Gene Expression; Humans; Paclitaxel; Phosphorylation; STAT3 Transcription Factor; Thioredoxins | 2016 |
Overexpression of miR-203 sensitizes paclitaxel (Taxol)-resistant colorectal cancer cells through targeting the salt-inducible kinase 2 (SIK2).
Topics: 3' Untranslated Regions; Antineoplastic Agents, Phytogenic; Blotting, Western; Caco-2 Cells; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Immunohistochemistry; MicroRNAs; Paclitaxel; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2016 |
Organoid Culture of Isolated Cells from Patient-derived Tissues with Colorectal Cancer.
Topics: Adult; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Doxorubicin; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mitomycin; Organoids; Paclitaxel; Rectal Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Regorafenib overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter in colorectal cancer: In vitro and in vivo study.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Mice; Paclitaxel; Phenylurea Compounds; Pyridines; Xenograft Model Antitumor Assays | 2017 |
Roscovitine synergizes with conventional chemo-therapeutic drugs to induce efficient apoptosis of human colorectal cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Paclitaxel; Purines; Roscovitine; Time Factors; Vinblastine | 2008 |
Combination effects of SC144 and cytotoxic anticancer agents.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cytotoxins; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Inhibitory Concentration 50; Injections, Intraperitoneal; Mice; Mice, Nude; Organoplatinum Compounds; Paclitaxel; Pyrazines; Quinoxalines; Xenograft Model Antitumor Assays | 2009 |
K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells.
Topics: Animals; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Death; Cell Nucleus; Colorectal Neoplasms; HCT116 Cells; Humans; Kinesins; Mad2 Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubules; Mitosis; Paclitaxel; Polyploidy; Repressor Proteins; Spindle Apparatus; Thiadiazoles; Xenograft Model Antitumor Assays | 2009 |
Inhibition of MEK sensitizes paclitaxel-induced apoptosis of human colorectal cancer cells by downregulation of GRP78.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Mitogen-Activated Protein Kinase Kinases; Paclitaxel; RNA, Small Interfering | 2009 |
Folate-mediated targeting of albumin conjugates of paclitaxel obtained through a heterogeneous phase system.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Carrier Proteins; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Chromatography, Gel; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Folate Receptors, GPI-Anchored; Folic Acid; HT29 Cells; Humans; Inhibitory Concentration 50; KB Cells; Nasopharyngeal Neoplasms; Paclitaxel; Polyethylene Glycols; Receptors, Cell Surface; Serum Albumin; Solubility; Technology, Pharmaceutical; Triazines | 2009 |
A chemosensitization screen identifies TP53RK, a kinase that restrains apoptosis after mitotic stress.
Topics: Adenocarcinoma; Apoptosis; Cisplatin; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Gene Knockdown Techniques; HCT116 Cells; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Mitosis; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Transfection | 2010 |
Phenotyping breast cancer cell lines EM-G3, HCC1937, MCF7 and MDA-MB-231 using 2-D electrophoresis and affinity chromatography for glutathione-binding proteins.
Topics: Adult; Aged; Alcohol Oxidoreductases; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Breast Neoplasms; Capecitabine; Carboplatin; Case-Control Studies; Chromatography, Affinity; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Electrophoresis, Gel, Two-Dimensional; Female; Fluorouracil; Glutathione S-Transferase pi; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Neurophysiology; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Phenotype; Survival Rate; Treatment Outcome | 2010 |
Detecting acute neurotoxicity during platinum chemotherapy by neurophysiological assessment of motor nerve hyperexcitability.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carboplatin; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Motor Neuron Disease; Neoplasm Staging; Neurophysiology; Neurotoxicity Syndromes; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Retrospective Studies; Survival Rate; Treatment Outcome | 2010 |
Penetration of paclitaxel and 5-fluorouracil in multicellular layers of human colorectal cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorouracil; HT29 Cells; Humans; Models, Biological; Paclitaxel; Transcytosis | 2011 |
Antitumour efficacy of two paclitaxel formulations for hyperthermic intraperitoneal chemotherapy (HIPEC) in an in vivo rat model.
Topics: Animals; Antineoplastic Agents; beta-Cyclodextrins; Cell Line, Tumor; Colorectal Neoplasms; Combined Modality Therapy; Disease Models, Animal; Hyperthermia, Induced; Injections, Intraperitoneal; Magnetic Resonance Imaging; Paclitaxel; Peritoneal Neoplasms; Positron-Emission Tomography; Rats; Time Factors; Tumor Burden | 2011 |
Dual blockade of phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways overcomes paclitaxel-resistance in colorectal cancer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Proliferation; Chromones; Colorectal Neoplasms; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Humans; Mitogen-Activated Protein Kinases; Morpholines; Paclitaxel; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Tumor Cells, Cultured | 2011 |
Paclitaxel induced B7-H1 expression in cancer cells via the MAPK pathway.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; B7-H1 Antigen; Carcinoma, Hepatocellular; Cell Line, Tumor; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; MAP Kinase Signaling System; Neoplasm Proteins; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Up-Regulation | 2011 |
Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Down-Regulation; Doxorubicin; Etoposide; Floxuridine; Fluorescent Antibody Technique; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomic Instability; Humans; Irinotecan; Metaphase; Paclitaxel; Polymerase Chain Reaction; Predictive Value of Tests; Protein Array Analysis; Reproducibility of Results; Tegafur; Tissue Array Analysis; Tumor Cells, Cultured; Up-Regulation; Uracil | 2012 |
The distribution and retention of paclitaxel and doxorubicin in multicellular layer cultures.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Biological Transport; Cell Culture Techniques; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Delayed-Action Preparations; Dose-Response Relationship, Drug; Doxorubicin; Humans; Kinetics; Microscopy, Fluorescence; Paclitaxel | 2012 |
Cell-penetrating peptide mimicking polymer-based combined delivery of paclitaxel and siRNA for enhanced tumor growth suppression.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell-Penetrating Peptides; Colorectal Neoplasms; Deoxycholic Acid; Drug Delivery Systems; Endocytosis; Gene Silencing; HCT116 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Molecular Weight; Paclitaxel; Polyethyleneimine; RNA, Small Interfering; Solubility | 2012 |
A dicarboxylic fatty acid derivative of paclitaxel for albumin-assisted drug delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biotransformation; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Colorectal Neoplasms; Drug Carriers; Drug Stability; Fatty Acids; Female; Glutarates; Half-Life; Humans; Hydrolysis; Injections, Intravenous; Mice; Mice, Inbred BALB C; Paclitaxel; Protein Binding; Serum Albumin; Serum Albumin, Human; Technology, Pharmaceutical; Tissue Distribution | 2012 |
On Bayesian methods of exploring qualitative interactions for targeted treatment.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bayes Theorem; Carboplatin; Cetuximab; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Computer Simulation; ErbB Receptors; Gefitinib; Genetic Markers; Humans; Lung Neoplasms; Mutation; Paclitaxel; Pharmacogenetics; Quinazolines; Regression Analysis; Survival Analysis | 2012 |
Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy.
Topics: Aged; Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Colon; Colorectal Neoplasms; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Neoplasm; Female; Humans; In Vitro Techniques; Ketoconazole; Male; Microsomes, Liver; Middle Aged; Mutation; Nifedipine; Oxidoreductases, N-Demethylating; Paclitaxel; Rectum | 2002 |
[Effectiveness of chemotherapy for outpatients with gastric or colorectal cancer].
Topics: Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Outpatients; Oxonic Acid; Paclitaxel; Pyridines; Retrospective Studies; Stomach Neoplasms; Tegafur | 2002 |
Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Gemcitabine; HCT116 Cells; Hedgehog Proteins; Humans; Paclitaxel; Pancreatic Neoplasms; Radiation, Ionizing; Time Factors; Veratrum Alkaloids | 2006 |
In-vivo efficacy of novel paclitaxel nanoparticles in paclitaxel-resistant human colorectal tumors.
Topics: Angiogenesis Inhibitors; Animals; Cell Line; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanostructures; Paclitaxel; Xenograft Model Antitumor Assays | 2006 |
Acquired resistance to the anticancer drug paclitaxel is associated with induction of cytochrome P450 2C8.
Topics: Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Base Sequence; Caco-2 Cells; Cell Survival; Colorectal Neoplasms; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Drug Resistance, Neoplasm; Enzyme Induction; Fluorouracil; Gene Expression; Genes, MDR; Humans; Lethal Dose 50; Paclitaxel; Pharmacogenetics | 2006 |
In vitro cytotoxicity of Phortress against colorectal cancer.
Topics: Biological Assay; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclohexanes; Endothelial Cells; Fatty Acids, Unsaturated; Fibroblasts; Humans; Neovascularization, Physiologic; Paclitaxel; Prodrugs; Sesquiterpenes; Thiazoles | 2006 |
Novel in vivo imaging shows up-regulation of death receptors by paclitaxel and correlates with enhanced antitumor effects of receptor agonist antibodies.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Colorectal Neoplasms; Drug Synergism; Female; Humans; Indium Radioisotopes; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Paclitaxel; Phosphorylation; Radionuclide Imaging; Receptors, TNF-Related Apoptosis-Inducing Ligand; Technetium; Tumor Suppressor Protein p53; Up-Regulation; Xenograft Model Antitumor Assays | 2006 |
VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases.
Topics: Animals; Antibodies; Antibody Formation; Cancer Vaccines; Cell Line, Tumor; Colorectal Neoplasms; Female; HT29 Cells; Humans; Immune Sera; Immunization; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Rhabdomyosarcoma; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2007 |
[The second report from Sapporo Tsukisamu hospital--chemotherapy for patients with advanced colorectal cancer].
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Nausea; Paclitaxel; Stomatitis; Survival Rate; Vomiting, Anticipatory | 2007 |
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells.
Topics: Animals; Cathepsin B; Cell Membrane; Colorectal Neoplasms; Fibrocystic Breast Disease; Humans; Hydrogen-Ion Concentration; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Microtubules; Nocodazole; Paclitaxel; Tumor Cells, Cultured | 1994 |
Eighty-seventh annual meeting of the American Association for Cancer Research. Washington, D,C., 20-24 April 1996.
Topics: Aged; Antineoplastic Agents; Breast; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Female; Genes, p53; Genes, Tumor Suppressor; Humans; Hyperplasia; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Pancreatic Neoplasms; Research; Survival Rate | 1996 |
The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Carboplatin; Cell Separation; Cisplatin; Colorectal Neoplasms; Cyclophosphamide; DNA Repair; DNA, Neoplasm; Doxorubicin; Enzyme Inhibitors; Etoposide; Humans; Melphalan; Paclitaxel; Tamoxifen; Thioguanine; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1998 |
Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Antineoplastic Agents; Carboplatin; Carrier Proteins; Cisplatin; Colorectal Neoplasms; Cyclophosphamide; DNA Adducts; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Endometrial Neoplasms; Etoposide; Female; Fluorouracil; Humans; Melphalan; Methylnitronitrosoguanidine; Mutagenesis; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Paclitaxel; Proto-Oncogene Proteins; Thioguanine; Tumor Cells, Cultured | 1997 |
Phase II study of prolonged infusion of Taxol in patients with metastatic colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Paclitaxel | 1998 |
Synergistic effect of paclitaxel and 4-hydroxytamoxifen on estrogen receptor-negative colon cancer and lung cancer cell lines.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Large Cell; Cell Division; Colorectal Neoplasms; Cytochrome c Group; Drug Synergism; Drug Therapy, Combination; Estrogen Receptor Modulators; G2 Phase; Humans; Lung Neoplasms; Mitochondria; Mitosis; Paclitaxel; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured | 1999 |
The effect of p53-function on the sensitivity to paclitaxel with or without hyperthermia in human colorectal carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Colorectal Neoplasms; Hot Temperature; Humans; Paclitaxel; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Survival of colorectal cancer cell lines treated with paclitaxel, radiation, and 5-FU: effect of TP53 or hMLH1 deficiency.
Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Carrier Proteins; Cell Survival; Chemotherapy, Adjuvant; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Inhibitors; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Inhibitor of Apoptosis Proteins; Membrane Proteins; Microtubule-Associated Proteins; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Paclitaxel; Proteins; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; RNA, Messenger; Survivin; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Low dose fractionated radiation enhances the radiosensitization effect of paclitaxel in colorectal tumor cells with mutant p53.
Topics: Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose Fractionation, Radiation; Genes, p53; HT29 Cells; Humans; Mutation; Paclitaxel; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 2000 |
Highlights of the Eighth European Cancer Conference.
Topics: Amifostine; Antineoplastic Agents; Breast Neoplasms; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Docetaxel; Head and Neck Neoplasms; Humans; Irinotecan; Neoplasms; Paclitaxel; Radiation Injuries; Radiation-Protective Agents; Taxoids; Vinblastine; Vinorelbine | 1995 |
Resistance to topoisomerase poisons due to loss of DNA mismatch repair.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Base Pair Mismatch; Breast Neoplasms; Carrier Proteins; Colorectal Neoplasms; Deoxycytidine; DNA Repair; DNA-Binding Proteins; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Endometrial Neoplasms; Enzyme Inhibitors; Epirubicin; Female; Gemcitabine; Humans; Intercalating Agents; Mitoxantrone; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Paclitaxel; Proto-Oncogene Proteins; Taxoids; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2001 |
[Globalization of anti-cancer therapies].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Carboplatin; Cisplatin; Colorectal Neoplasms; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Neoplasms; Ovarian Neoplasms; Paclitaxel; Prostatic Neoplasms; Stomach Neoplasms | 2002 |
Clinical trials of new anticancer agents in recent years in China.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; China; Clinical Trials as Topic; Colorectal Neoplasms; Docetaxel; Female; Humans; Lung Neoplasms; Male; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Paclitaxel; Taxoids; Vinblastine; Vinorelbine | 2002 |
Antiproliferative Effects of Hop-derived Prenylflavonoids and Their Influence on the Efficacy of Oxaliplatine, 5-fluorouracil and Irinotecan in Human ColorectalC Cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Beer; Caco-2 Cells; Caspases; Cell Line, Tumor; Colorectal Neoplasms; Drug Combinations; Drug Interactions; Feeding Behavior; Flavanones; Flavonoids; Fluorouracil; Humans; Humulus; Irinotecan; Oxaliplatin; Plant Extracts; Propiophenones; Reactive Oxygen Species; Treatment Outcome; Xanthones | 2019 |