Page last updated: 2024-08-23

paclitaxel and Cognitive Decline

paclitaxel has been researched along with Cognitive Decline in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (41.67)24.3611
2020's7 (58.33)2.80

Authors

AuthorsStudies
Argyriou, AA; Bruna, J; Cavaletti, G; Ferrari, S; Kalofonos, HP; Kalofonou, F; Karteri, S; Mariotto, S; Simo, M; Velissaris, D1
Guo, YX; Liu, JX; Liu, X; Tang, M; Wang, GY; Wang, XL; Zhao, S1
Grant, CV; Otero, JJ; Otto, LD; Pyter, LM; Strehle, LD; Sullivan, KA; Wentworth, KM1
Guo, YX; He, TY; Li, HZ; Li, Z; Liu, X; Tang, M; Wang, XL; Zhao, S1
Grant, CV; Jordan, K; Pyter, LM; Seng, MM1
Ahire, C; Balasubramanian, P; Campisi, J; Csipo, T; Csiszar, A; DelFavero, J; Faakye, JA; Gulej, R; Kiss, T; Kuan-Celarier, A; Mukli, P; Nagaraja, R; Nyul-Toth, A; Tang, Q; Tarantini, A; Tarantini, S; Ungvari, A; Ungvari, Z; Yabluchanskiy, A; Yan, F1
Choi, BY; Choi, HC; Hong, DK; Kho, AR; Kim, H; Kim, JH; Lee, BE; Lee, SH; Suh, SW1
Chen, L; Ding, W; Doheny, JT; Lim, G; Mao, J; Shen, S; Tate, S; Yang, J; Yang, L; You, Z; Zhang, S1
Choi, BY; Suh, SW1
Lee, JR; Oh, PJ1
Lin, H; Tao, L; Wang, L; Xu, X; Yan, Y; Yu, Y; Zhang, J1
Hu, J; Li, L; Ma, P; Zhang, S; Zhu, H1

Reviews

1 review(s) available for paclitaxel and Cognitive Decline

ArticleYear
Antimicrotubule Agent-Induced Zinc Neurotoxicity.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:7

    Topics: Animals; Cation Transport Proteins; Cell Death; Cognitive Dysfunction; Colchicine; Disease Models, Animal; Hippocampus; Humans; Mice; Microtubules; Neurogenesis; Neurons; Neurotoxicity Syndromes; Paclitaxel; Presynaptic Terminals; Tubulin Modulators; Vincristine

2018

Trials

1 trial(s) available for paclitaxel and Cognitive Decline

ArticleYear
Paclitaxel induces cognitive impairment via necroptosis, decreased synaptic plasticity and M1 polarisation of microglia.
    Pharmaceutical biology, 2022, Volume: 60, Issue:1

    Topics: Animals; Cognitive Dysfunction; Hippocampus; Mice; Microglia; Necroptosis; Neuronal Plasticity; Paclitaxel; Tumor Necrosis Factor-alpha

2022

Other Studies

10 other study(ies) available for paclitaxel and Cognitive Decline

ArticleYear
Serum neurofilament light chain levels as biomarker of paclitaxel-induced cognitive impairment in patients with breast cancer: a prospective study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:2

    Topics: Aged; Biomarkers; Breast Neoplasms; Cognitive Dysfunction; Female; Humans; Intermediate Filaments; Middle Aged; Multiple Sclerosis; Paclitaxel; Prospective Studies

2022
Microglia are implicated in the development of paclitaxel chemotherapy-associated cognitive impairment in female mice.
    Brain, behavior, and immunity, 2023, Volume: 108

    Topics: Animals; Cognitive Dysfunction; Cytokines; Female; Hippocampus; Mice; Mice, Inbred C57BL; Microglia; Paclitaxel

2023
Resveratrol Improves Paclitaxel-Induced Cognitive Impairment in Mice by Activating SIRT1/PGC-1α Pathway to Regulate Neuronal State and Microglia Cell Polarization.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Interleukin-10; Interleukin-4; Mice; Microglia; Paclitaxel; Resveratrol; Sirtuin 1; Transcription Factors

2023
Antibiotic treatment inhibits paclitaxel chemotherapy-induced activity deficits in female mice.
    PloS one, 2023, Volume: 18, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cognitive Dysfunction; Drug-Related Side Effects and Adverse Reactions; Fatigue; Female; Mice; Paclitaxel

2023
Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain.
    Aging cell, 2023, Volume: 22, Issue:7

    Topics: Animals; Chemotherapy-Related Cognitive Impairment; Cognitive Dysfunction; Disease Models, Animal; Endothelial Cells; Mice; Paclitaxel; Senotherapeutics

2023
The cancer chemotherapeutic agent paclitaxel (Taxol) reduces hippocampal neurogenesis via down-regulation of vesicular zinc.
    Scientific reports, 2017, 09-15, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cognitive Dysfunction; Down-Regulation; Hippocampus; Mice, Inbred C57BL; Neurogenesis; Paclitaxel; Synaptic Vesicles; Zinc

2017
Cognitive impairment in a rat model of neuropathic pain: role of hippocampal microtubule stability.
    Pain, 2018, Volume: 159, Issue:8

    Topics: Animals; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Learning; Long-Term Potentiation; Male; Memory; Microtubules; Neuralgia; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Tubulin Modulators

2018
[Effect of Cancer Symptoms and Fatigue on Chemotherapy-related Cognitive Impairment and Depression in People with Gastrointestinal Cancer].
    Journal of Korean Academy of Nursing, 2016, Volume: 46, Issue:3

    Topics: Adult; Aged; Anemia; Antineoplastic Agents; Anxiety; Camptothecin; Cognitive Dysfunction; Depression; Drug Therapy, Combination; Fatigue; Female; Fluorouracil; Gastrointestinal Neoplasms; Hemoglobins; Humans; Irinotecan; Male; Memory; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Surveys and Questionnaires; Translating

2016
Impairment of the executive function in breast cancer patients receiving chemotherapy treatment: a functional MRI study.
    European journal of cancer care, 2017, Volume: 26, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Breast Neoplasms; Case-Control Studies; Cognitive Dysfunction; Cyclophosphamide; Doxorubicin; Executive Function; Female; Frontal Lobe; Functional Neuroimaging; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Middle Aged; Neural Pathways; Neuropsychological Tests; Paclitaxel; Trail Making Test

2017
Polysaccharide of
    Pharmaceutical biology, 2020, Volume: 58, Issue:1

    Topics: Alzheimer Disease; Animals; Apoptosis; Cell Line; Cell Survival; Cognitive Dysfunction; Disease Models, Animal; Dose-Response Relationship, Drug; Galactose; Maze Learning; Mice; Mice, Inbred C57BL; Oxidative Stress; Polysaccharides; Taxus

2020