Page last updated: 2024-08-23

paclitaxel and Cirrhosis

paclitaxel has been researched along with Cirrhosis in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.25)18.2507
2000's6 (18.75)29.6817
2010's18 (56.25)24.3611
2020's6 (18.75)2.80

Authors

AuthorsStudies
Chen, L; Duan, H; Gao, Z; Hou, Y; Huang, W; Jin, M; Liu, C; Liu, W; Liu, Y; Xin, X; Zhang, X; Zhang, Z; Zhao, H1
Chen, J; Jiang, H; Xia, Y; Xu, F; Zhang, D; Zhang, G1
Chen, S; Chen, ZW; Hu, JF; Huang, L; Huang, Y; Kang, FP; Li, G; Liao, CY; Lin, CF; Lin, HY; Tian, YF; Wang, ZW; Wu, YD; Xie, CK; Zhu, SC1
Chen, X; He, Q; Li, M; Liu, Y; Sheng, Q; Shi, K; Wang, Y; Yu, Q; Zhang, Z1
Adir, O; Alyan, M; Binenbaum, Y; Dvir, T; Fridman, E; Gibori, H; Gil, Z; Hershkovitz, D; Kasten, S; Koren, L; Krayem, M; Krinsky, N; Liba, L; Lübtow, MM; Luxenhofer, R; Milman, N; Mumblat, Y; Noor, N; Ofir, S; Poley, M; Satchi-Fainaro, R; Schroeder, A; Shainsky-Roitman, J; Shklover, J; Simon, A; Yaari, Z; Zinger, A1
Kang, JS; Lee, EY; Son, SS1
Amoroso, A; Calvo, PL; Catalano, S; Chiadò, C; Chiusa, L; David, E; Deaglio, S; Dell'Olio, D; Isolato, G; Pinon, M; Pizzol, A; Romagnoli, R; Tandoi, F1
Annan, DA; Cong, L; Hida, K; Hida, Y; Maishi, N; Morimoto, H; Morimoto, M; Nam, JM; Young, MF1
Benoit, JP; Contini, A; Hureaux, J; Lacoeuille, F; Lagarce, F; Rousselet, MC; Saulnier, P; Urban, T1
Grabow, N; Guthoff, RF; Reske, T; Schmidt, W; Schmitz, KP; Siewert, S; Stahnke, T; Wree, A1
Chen, X; Chen, Y; Ding, J; Luan, J; Shen, W; Sun, J; Yang, X; Yu, L; Zhang, Z1
Chen, L; Gao, Z; Huang, W; Jin, M; Jin, Z; Wang, M; Wang, Q1
Fujimura, T; Fushida, S; Harada, S; Kinoshita, J; Ninomiya, I; Ohta, T; Oyama, K; Tajima, H; Terai, S; Tsukada, T; Yagi, Y1
Adden, N; Braune, M; Riedmüller, J; Savard, C; Waksman, R; Wittchow, E1
Afari, ME; Buszman, PP; Conditt, GB; Granada, JF; Kaluza, GL; McGregor, JC; Peppas, A; Rousselle, SD; Stenoien, M; Tellez, A1
Chen, J; Dong, Z; He, Z; Wang, S; Xiang, X; Xu, X; Yang, J; Yang, R; Zhang, D; Zhang, L; Zhao, Y1
Giles, RH; Lilien, MR; Slaats, GG1
Han, JS; Heo, NJ; Joo, KW; Jung, ES; Kim, DK; Kim, S; Lee, J1
Althoff, CE; Günther, RW; Hamm, B; Langmann, M; Marticorena Garcia, SR; Schnorr, B1
Han, SJ; Kim, JH; Kim, JI; Park, KM1
Bergler-Klein, J; Gray, WA; Gyöngyösi, M; Jambrik, Z; Lukovic, D; Maurer, G; Pavo, IJ; Pavo, N; Plass, CA; Sabdyusheva, I; Samaha, E; Stahnke, S; von Strandmann, RP; Zlabinger, K1
Kolodgie, FD; Ladich, E; Mori, H; Pacheco, E; Virmani, R; Yahagi, K1
Albert, PS; Citrin, D; Colevas, AD; Cooley-Zgela, T; Cotrim, A; Herscher, L; Likhacheva, A; Mansueti, J; Morris, JC; Rudy, SF; Russo, A; Sciuto, L; Smith, S; Solomon, B; Van Waes, C1
Baim, DS; Herbst, TJ; Huibregtse, B; Nakazawa, G; Poff, B; Schwartz, RS; Virmani, R; Wilson, GJ1
Kanwar, YS; Kondeti, VK; Ling, G; Liu, F; Liu, Y; Sun, L; Xiang, X; Xiao, L; Yang, Y; Zhan, M; Zhang, D; Zhu, X1
Guthoff, R; Kastner, C; Löbler, M; Schmitz, KP; Stachs, O; Stahnke, T; Sternberg, K; Wree, A1
Dong, C; Goldschmidt-Clermont, PJ; Hummers, L; Liu, X; Wang, T; Wigley, FM; Zhu, S1
Choi, HS; Choi, JW; Kuver, R; Lee, SP; Savard, CE1
Jampel, HD; Leong, KW; Quigley, HA; Thibault, D; Uppal, P1
Eisele, DW; Forastiere, AA; Lee, DJ; Westra, WH1
Ajaikumar, BS; Cleveland, MG; Reganti, R1
Ahmadi, MA; Booser, D; Esmaeli, B; Valero, V1

Reviews

1 review(s) available for paclitaxel and Cirrhosis

ArticleYear
Nephronophthisis: should we target cysts or fibrosis?
    Pediatric nephrology (Berlin, Germany), 2016, Volume: 31, Issue:4

    Topics: Animals; Ciliopathies; Fibrosis; Humans; Kidney; Kidney Diseases, Cystic; Kidney Failure, Chronic; Microtubules; Paclitaxel; Risk Factors; Signal Transduction; Treatment Outcome; Urological Agents

2016

Trials

1 trial(s) available for paclitaxel and Cirrhosis

ArticleYear
Squamous cell granulomas of the neck: histologic regression of metastatic squamous cell carcinoma following chemotherapy and/or radiotherapy.
    Head & neck, 1998, Volume: 20, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Culture Techniques; Diagnosis, Differential; Female; Fibrosis; Fluorouracil; Granuloma, Foreign-Body; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lymphatic Metastasis; Male; Middle Aged; Neck; Neck Dissection; Neoplasm Staging; Paclitaxel; Radiotherapy, Adjuvant; Registries; Remission Induction; Tirapazamine; Triazines

1998

Other Studies

30 other study(ies) available for paclitaxel and Cirrhosis

ArticleYear
Sequential Delivery of Quercetin and Paclitaxel for the Fibrotic Tumor Microenvironment Remodeling and Chemotherapy Potentiation via a Dual-Targeting Hybrid Micelle-in-Liposome System.
    ACS applied materials & interfaces, 2022, Mar-02, Volume: 14, Issue:8

    Topics: Cell Line, Tumor; Drug Delivery Systems; Fibrosis; Humans; Liposomes; Micelles; Paclitaxel; Quercetin; Tumor Microenvironment

2022
Low dose Taxol ameliorated renal fibrosis in mice with diabetic kidney disease by downregulation of HIPK2.
    Life sciences, 2023, May-01, Volume: 320

    Topics: Animals; Collagen; Diabetes Mellitus; Diabetic Nephropathies; Down-Regulation; Fibrosis; Kidney; Mice; Paclitaxel; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Suppressor Protein p53

2023
A Novel Trojan Horse Nanotherapy Strategy Targeting the cPKM-STMN1/TGFB1 Axis for Effective Treatment of Intrahepatic Cholangiocarcinoma.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:32

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cholangiocarcinoma; Fibrosis; Humans; Paclitaxel; RNA-Binding Proteins; RNA, Small Interfering; Stathmin; Transforming Growth Factor beta1; Tumor Microenvironment

2023
Synergistic cytotoxicity and co-autophagy inhibition in pancreatic tumor cells and cancer-associated fibroblasts by dual functional peptide-modified liposomes.
    Acta biomaterialia, 2019, Volume: 99

    Topics: Animals; Antineoplastic Agents; Autophagy; Cancer-Associated Fibroblasts; Carcinoma, Pancreatic Ductal; Disease Progression; Female; Fibrosis; Humans; Hydroxychloroquine; Irinotecan; Liposomes; Mice; Mice, Nude; Nanomedicine; Neoplasm Metastasis; Neoplasm Transplantation; NIH 3T3 Cells; Paclitaxel; Pancreatic Neoplasms; Peptides; Wound Healing

2019
Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors.
    ACS nano, 2019, 10-22, Volume: 13, Issue:10

    Topics: Adenocarcinoma; Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Membrane Permeability; Collagen; Collagenases; Disease Models, Animal; Extracellular Matrix; Fibrosis; Humans; Liposomes; Mice; Nanoparticles; Paclitaxel; Pancreas; Tumor Microenvironment

2019
Paclitaxel Ameliorates Palmitate-Induced Injury in Mouse Podocytes.
    Medical science monitor basic research, 2020, Dec-16, Volume: 26

    Topics: Animals; Antioxidants; Apoptosis; Cell Death; Cell Line; Cell Survival; Endoplasmic Reticulum Stress; Fibrosis; Inflammation; Mice; Paclitaxel; Palmitates; Podocytes; Reactive Oxygen Species

2020
Evaluation of Graft Fibrosis, Inflammation, and Donor-specific Antibodies at Protocol Liver Biopsies in Pediatric Liver Transplant Patients: A Single-center Experience.
    Transplantation, 2022, 01-01, Volume: 106, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Child; Cross-Sectional Studies; Doxorubicin; Fibrosis; Graft Rejection; Graft Survival; HLA Antigens; Humans; Inflammation; Isoantibodies; Liver; Liver Transplantation; Paclitaxel; Retrospective Studies

2022
Inhibition of stromal biglycan promotes normalization of the tumor microenvironment and enhances chemotherapeutic efficacy.
    Breast cancer research : BCR, 2021, 05-10, Volume: 23, Issue:1

    Topics: Angiopoietin-2; Animals; Biglycan; Breast Neoplasms; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Female; Fibrosis; Humans; Mice; Mice, Knockout; Neoplasm Metastasis; Neovascularization, Pathologic; Paclitaxel; Prognosis; Signal Transduction; Stromal Cells; Treatment Outcome; Tumor Microenvironment; Tumor Necrosis Factor-alpha

2021
Absence of lung fibrosis after a single pulmonary delivery of lipid nanocapsules in rats.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Aerosols; Animals; Biological Products; Cell Line; Drug Carriers; Drug Delivery Systems; Female; Fibrosis; Humans; Lipids; Lung; Nanocapsules; Paclitaxel; Phospholipids; Pulmonary Alveoli; Rats, Sprague-Dawley; Surface Tension; Tissue Distribution

2017
Development of a biodegradable antifibrotic local drug delivery system for glaucoma microstents.
    Bioscience reports, 2018, 08-31, Volume: 38, Issue:4

    Topics: Animals; Caffeic Acids; Drug Delivery Systems; Drug-Eluting Stents; Fibrosis; Glaucoma; Male; Paclitaxel; Phenylethyl Alcohol; Pyridones; Rats; Rats, Wistar

2018
Thermogel Loaded with Low-Dose Paclitaxel as a Facile Coating to Alleviate Periprosthetic Fibrous Capsule Formation.
    ACS applied materials & interfaces, 2018, Sep-12, Volume: 10, Issue:36

    Topics: Animals; Coated Materials, Biocompatible; Fibrosis; Foreign-Body Reaction; Gels; Micelles; Paclitaxel; Prostheses and Implants; Rats

2018
Improving the anti-keloid outcomes through liposomes loading paclitaxel-cholesterol complexes.
    International journal of nanomedicine, 2019, Volume: 14

    Topics: Animals; Apoptosis; Cell Cycle; Cell Proliferation; Cell Survival; Cells, Cultured; Cholesterol; Collagen Type I; Cytokines; Endocytosis; Female; Fibroblasts; Fibrosis; Fluorescence; Humans; Keloid; Liposomes; Male; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Wound Healing

2019
Low-dose paclitaxel modulates tumour fibrosis in gastric cancer.
    International journal of oncology, 2013, Volume: 42, Issue:4

    Topics: Actins; Antigens, CD; Antineoplastic Agents, Phytogenic; Cadherins; Cell Line, Tumor; Cell Shape; Cisplatin; Collagen Type I; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Fibrosis; Fluorouracil; Gene Expression; Humans; Paclitaxel; Phosphorylation; Protein Processing, Post-Translational; Smad2 Protein; Stomach Neoplasms; Transforming Growth Factor beta

2013
Bioresorbable drug-eluting magnesium-alloy scaffold: design and feasibility in a porcine coronary model.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2013, Apr-22, Volume: 8, Issue:12

    Topics: Absorbable Implants; Alloys; Animals; Cardiovascular Agents; Coronary Angiography; Coronary Vessels; Drug-Eluting Stents; Feasibility Studies; Female; Fibrosis; Kinetics; Magnesium; Male; Materials Testing; Models, Animal; Molecular Weight; Neointima; Paclitaxel; Percutaneous Coronary Intervention; Polyglactin 910; Prosthesis Design; Swine; Swine, Miniature

2013
Tissue uptake, distribution, and healing response after delivery of paclitaxel via second-generation iopromide-based balloon coating: a comparison with the first-generation technology in the iliofemoral porcine model.
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:8

    Topics: Angioplasty, Balloon; Animals; Arterial Occlusive Diseases; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Constriction, Pathologic; Contrast Media; Disease Models, Animal; Equipment Design; Femoral Artery; Fibrosis; Hyperlipoproteinemia Type II; Iliac Artery; Iohexol; Neointima; Paclitaxel; Radiography; Sus scrofa; Tissue Distribution; Vascular Access Devices; Wound Healing

2013
Paclitaxel attenuates renal interstitial fibroblast activation and interstitial fibrosis by inhibiting STAT3 signaling.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Dose-Response Relationship, Drug; Fibroblasts; Fibrosis; Kidney; Male; Mice; Mice, Inbred C57BL; Nephritis, Interstitial; Paclitaxel; STAT3 Transcription Factor; Tubulin

2015
Low-dose paclitaxel ameliorates renal fibrosis by suppressing transforming growth factor-β1-induced plasminogen activator inhibitor-1 signaling.
    Nephrology (Carlton, Vic.), 2016, Volume: 21, Issue:7

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Matrix Proteins; Fibrosis; Kidney; Kidney Diseases; Male; Mitogen-Activated Protein Kinases; Paclitaxel; Plasminogen Activator Inhibitor 1; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Smad3 Protein; Time Factors; Transforming Growth Factor beta1; Tubulin Modulators; Ureteral Obstruction

2016
Use of Paclitaxel-Coated Balloon Catheter Dilation to Reduce In-Stent Restenosis in Transjugular Intrahepatic Portosystemic Shunt (TIPS).
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2016, Volume: 188, Issue:4

    Topics: Aged; Angioplasty, Balloon; Combined Modality Therapy; Drug-Eluting Stents; Female; Fibrosis; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Paclitaxel; Portasystemic Shunt, Transjugular Intrahepatic; Treatment Outcome; Tubulin Modulators

2016
Inhibition of microtubule dynamics impedes repair of kidney ischemia/reperfusion injury and increases fibrosis.
    Scientific reports, 2016, 06-08, Volume: 6

    Topics: Acetylation; Animals; Cell Cycle Checkpoints; Cell Proliferation; Checkpoint Kinase 2; Colchicine; Disease Progression; Epithelial Cells; Fibrosis; Kidney; Macrophages; Male; Mice; Microtubules; Monocytes; Paclitaxel; Phosphorylation; RAW 264.7 Cells; Reperfusion Injury; Tubulin; Wound Healing

2016
Coating of intravascular balloon with paclitaxel prevents constrictive remodeling of the dilated porcine femoral artery due to inhibition of intimal and media fibrosis.
    Journal of materials science. Materials in medicine, 2016, Volume: 27, Issue:8

    Topics: Angiography; Angioplasty, Balloon; Animals; Coated Materials, Biocompatible; Equipment Design; Femoral Artery; Fibrosis; Hyperplasia; Iliac Artery; Materials Testing; Models, Animal; Neointima; Paclitaxel; Sus scrofa; Swine; Tomography, Optical Coherence; Tunica Intima; Tunica Media; Vasoconstriction; Vasodilation

2016
Comparison of Particulate Embolization after Femoral Artery Treatment with IN.PACT Admiral versus Lutonix 035 Paclitaxel-Coated Balloons in Healthy Swine.
    Journal of vascular and interventional radiology : JVIR, 2016, Volume: 27, Issue:11

    Topics: Angioplasty, Balloon; Animals; Arterioles; Cardiovascular Agents; Coated Materials, Biocompatible; Coronary Vessels; Embolism; Equipment Design; Femoral Artery; Fibrosis; Models, Animal; Muscle, Skeletal; Necrosis; Neointima; Paclitaxel; Sus scrofa; Time Factors; Vascular Access Devices

2016
Long-term outcomes and toxicity of concurrent paclitaxel and radiotherapy for locally advanced head-and-neck cancer.
    International journal of radiation oncology, biology, physics, 2009, Jul-15, Volume: 74, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Administration Schedule; Feasibility Studies; Female; Fibrosis; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Paclitaxel; Prospective Studies; Radiation Injuries; Radiotherapy Dosage; Skin; Survival Rate; Treatment Outcome

2009
Comparison of inflammatory response after implantation of sirolimus- and paclitaxel-eluting stents in porcine coronary arteries.
    Circulation, 2009, Jul-14, Volume: 120, Issue:2

    Topics: Animals; Arteritis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Eosinophils; Female; Fibrin; Fibrosis; Granuloma, Foreign-Body; Paclitaxel; Sirolimus; Swine; Tunica Intima

2009
Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192.
    The Journal of pathology, 2011, Volume: 225, Issue:3

    Topics: Animals; Cells, Cultured; Creatinine; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Drug Evaluation, Preclinical; Extracellular Matrix; Fibrosis; Gene Expression Regulation; Hypertension, Renal; Kidney; Male; MicroRNAs; Nephrectomy; Paclitaxel; Proteinuria; Rats; Rats, Wistar; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1; Tubulin Modulators

2011
Different fibroblast subpopulations of the eye: a therapeutic target to prevent postoperative fibrosis in glaucoma therapy.
    Experimental eye research, 2012, Volume: 100

    Topics: Adipose Tissue; Cell Culture Techniques; Cell Proliferation; Choroid; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Fluorescent Antibody Technique, Indirect; Glaucoma; Glaucoma Drainage Implants; Humans; Immunoblotting; Mitomycin; Paclitaxel; Sclera; Tenon Capsule; Trabecular Meshwork; Trabeculectomy; Transforming Growth Factor beta1

2012
Paclitaxel modulates TGFbeta signaling in scleroderma skin grafts in immunodeficient mice.
    PLoS medicine, 2005, Volume: 2, Issue:12

    Topics: Adult; Animals; Antineoplastic Agents, Phytogenic; Biopsy; Dose-Response Relationship, Drug; Female; Fibrosis; Humans; Male; Mice; Mice, SCID; Middle Aged; Neovascularization, Pathologic; Paclitaxel; Phenotype; Scleroderma, Systemic; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Transplantation, Heterologous

2005
Paclitaxel interrupts TGF-beta1 signaling between gallbladder epithelial cells and myofibroblasts.
    The Journal of surgical research, 2007, Volume: 141, Issue:2

    Topics: Animals; Cell Communication; Cell Proliferation; Cells, Cultured; Collagen Type I; Epithelial Cells; Fibroblasts; Fibrosis; Gallbladder; L-Lactate Dehydrogenase; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Paclitaxel; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2007
Glaucoma filtration surgery in nonhuman primates using taxol and etoposide in polyanhydride carriers.
    Investigative ophthalmology & visual science, 1993, Volume: 34, Issue:11

    Topics: Animals; Anterior Eye Segment; Drug Carriers; Drug Delivery Systems; Etoposide; Fibrosis; Glaucoma; Intraocular Pressure; Laser Therapy; Macaca fascicularis; Male; Paclitaxel; Polymers; Sclera; Sclerostomy

1993
Cutaneous fibrosis induced by docetaxel: a case report.
    Cancer, 2000, Mar-01, Volume: 88, Issue:5

    Topics: Adult; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Docetaxel; Drug Eruptions; Female; Fibrosis; Humans; Paclitaxel; Skin; Taxoids

2000
Canalicular stenosis secondary to docetaxel (taxotere): a newly recognized side effect.
    Ophthalmology, 2001, Volume: 108, Issue:5

    Topics: Adult; Antineoplastic Agents, Phytogenic; Docetaxel; Female; Fibrosis; Humans; Lacrimal Apparatus; Lacrimal Apparatus Diseases; Lacrimal Duct Obstruction; Middle Aged; Paclitaxel; Taxoids; Tears

2001