Page last updated: 2024-08-23

paclitaxel and Chromosome-Defective Micronuclei

paclitaxel has been researched along with Chromosome-Defective Micronuclei in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (46.15)18.2507
2000's5 (38.46)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Florian, S; Mitchison, TJ; Pineda, J; Shi, J1
Gong, Y; Guo, H; Jiang, H; Liu, Q; Liu, Z; Shao, C; Sun, Z; Tischfield, JA; Xu, B; Zou, Y1
Dong, F; Guo, W; Lei, W; Zeng, C1
Hegde, SG; Hubbard, RD; Leal, RM; Mooberry, SL; Randall-Hlubek, DA; Wender, PA; Zhang, L1
Böhm, KJ; Bolt, HM; Bonacker, D; Degen, GH; Prots, I; Stoiber, T; Thier, R; Unger, E; Wang, M1
Bakalarz, R; Banasik, A; Góźdź, S; Lankoff, A; Lesisz, D; Lisowska, H; Padjas, A; Wojcik, A1
Ashby, J; Tinwell, H1
Jagetia, GC; Nayak, V1
Adiga, SK; Jagetia, GC1
Corvin, J; Gabbert, HE; Gerharz, CD; Reinecke, P1
Geard, CR; Hall, EJ; Mellado, W; Pandita, TK; Rakovitch, E; Sawant, S1
Gabbert, HE; Gerharz, CD; Knopf, C; Reinecke, P; Schmitz, M; Schneider, EM1
Cabral, TF; Chandra, J; Mcconker, J; Multani, AS; Pathak, S; Sen, S1

Reviews

1 review(s) available for paclitaxel and Chromosome-Defective Micronuclei

ArticleYear
Is inflammatory micronucleation the key to a successful anti-mitotic cancer drug?
    Open biology, 2017, Volume: 7, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Antimitotic Agents; Antineoplastic Agents; Humans; Micronuclei, Chromosome-Defective; Neoplasms; Paclitaxel

2017

Other Studies

12 other study(ies) available for paclitaxel and Chromosome-Defective Micronuclei

ArticleYear
Replication stress induces micronuclei comprising of aggregated DNA double-strand breaks.
    PloS one, 2011, Apr-15, Volume: 6, Issue:4

    Topics: Animals; Aphidicolin; Cell Line; DNA Breaks, Double-Stranded; DNA Replication; Histones; Humans; Hydroxyurea; Mice; Micronuclei, Chromosome-Defective; Mutation; Paclitaxel; Replication Protein A; RNA, Small Interfering; S Phase; Stress, Physiological; Thymidine

2011
Paclitaxel-induced apoptosis in osteosarcoma cell line U-2 OS.
    Chinese medical journal, 2002, Volume: 115, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Micronuclei, Chromosome-Defective; Microscopy, Electron; Osteosarcoma; Paclitaxel; Tumor Cells, Cultured

2002
Microtubule-stabilizing agents based on designed laulimalide analogues.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Jun-08, Volume: 101, Issue:23

    Topics: Animals; Apoptosis; Cell Cycle; Cell Division; Cell Line; Drug Design; Drug Resistance; HeLa Cells; Humans; Macrolides; Micronuclei, Chromosome-Defective; Microtubules; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Spindle Apparatus; Taxoids; Tubulin

2004
Genotoxicity of inorganic lead salts and disturbance of microtubule function.
    Environmental and molecular mutagenesis, 2005, Volume: 45, Issue:4

    Topics: Animals; Cell Line; Cell Nucleus; Cell Proliferation; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Kinesins; Lead; Micronuclei, Chromosome-Defective; Micronucleus Tests; Microscopy, Electron, Transmission; Microtubules; Neutral Red; Nitrates; Organometallic Compounds; Paclitaxel; Tubulin; Tubulin Modulators

2005
Cytogenetic damage in lymphocytes of patients undergoing therapy for small cell lung cancer and ovarian carcinoma.
    Toxicology and applied pharmacology, 2005, Dec-01, Volume: 209, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Kinetics; Leukocyte Count; Lung Neoplasms; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Middle Aged; Ovarian Neoplasms; Paclitaxel

2005
Genetic toxicity and potential carcinogenicity of taxol.
    Carcinogenesis, 1994, Volume: 15, Issue:8

    Topics: Animals; Carcinogens; DNA; Erythropoiesis; Male; Mice; Mice, Inbred CBA; Micronuclei, Chromosome-Defective; Paclitaxel

1994
Treatment of mice with a novel antineoplastic agent taxol before irradiation increases the frequency of micronuclei in the bone marrow.
    Mutation research, 1996, Feb-01, Volume: 349, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bone Marrow; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Erythrocytes; Gamma Rays; Male; Mice; Micronuclei, Chromosome-Defective; Mutagens; Paclitaxel; Time Factors

1996
Correlation between micronuclei induction and cell survival in V79 cells exposed to paclitaxel (taxol) in conjunction with radiation.
    Mutation research, 1997, Jun-09, Volume: 377, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cell Line; Cell Survival; Chromosome Aberrations; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; Gamma Rays; Micronuclei, Chromosome-Defective; Paclitaxel; Radiation-Sensitizing Agents

1997
Antiproliferative effects of paclitaxel (Taxol) on human renal clear cell carcinomas in vitro.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Renal Cell; Cell Survival; Drug Screening Assays, Antitumor; Humans; Kidney Neoplasms; Micronuclei, Chromosome-Defective; Micronucleus Tests; Microtubules; Paclitaxel; Solvents; Time Factors; Tumor Cells, Cultured

1997
Paclitaxel sensitivity correlates with p53 status and DNA fragmentation, but not G2/M accumulation.
    International journal of radiation oncology, biology, physics, 1999, Jul-15, Volume: 44, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Genes, p53; Humans; Micronuclei, Chromosome-Defective; Paclitaxel; Tumor Cells, Cultured; Tumor Stem Cell Assay

1999
Growth inhibitory effects of paclitaxel on human epithelioid sarcoma in vitro: heterogeneity of response and the multidrug resistance phenotype.
    Cancer, 2000, Apr-01, Volume: 88, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Differentiation; Cell Division; Drug Resistance, Multiple; Flow Cytometry; Humans; Micronuclei, Chromosome-Defective; Microscopy, Electron; Microtubules; Multidrug Resistance-Associated Proteins; Paclitaxel; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma; Time Factors; Tumor Cells, Cultured

2000
Cell death in paclitaxel-dependent chinese hamster ovary cells is initiated by the loss of telomeric DNA repeats.
    Oncology research, 1999, Volume: 11, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Southern; Cell Death; CHO Cells; Chromosomes; Cricetinae; DNA; DNA Fragmentation; In Situ Hybridization, Fluorescence; Metaphase; Micronuclei, Chromosome-Defective; Mutation; Paclitaxel; Polyploidy; Repetitive Sequences, Nucleic Acid; Telomere; Time Factors

1999