paclitaxel has been researched along with Astrocytoma, Grade IV in 162 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 18 (11.11) | 18.2507 |
2000's | 37 (22.84) | 29.6817 |
2010's | 75 (46.30) | 24.3611 |
2020's | 32 (19.75) | 2.80 |
Authors | Studies |
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Bakalara, N; Clarion, L; Filippini, D; Hirlemann, MH; Jacquard, C; Lecouvey, M; Loiseau, S; Pirat, JL; Sainte-Catherine, O; Virieux, D; Volle, JN | 1 |
Abbassi, RH; Day, BW; Font, JS; Hoque, M; Johns, TG; Kassiou, M; Munoz, L; Phoa, AF; Reekie, TA; Ryan, RM; Stringer, BW; Zhou, Q | 1 |
Chen, HC; Dai, Z; Liu, H; Liu, HY; Liu, YP; Luo, XD; Wang, B; Yan, H; Yang, D; Zhao, LX; Zhao, XD; Zhao, YL; Zhu, PF; Zhu, YY | 1 |
Kang, JH; Ko, YT; Kwon, YJ; Lee, DS; Turabee, MH | 1 |
Ali, MY; Ebeid, K; Griguer, C; Naguib, Y; Oliva, C; Quarterman, JC; Salem, AK; Wiwatchaitawee, K | 1 |
Chen, H; Wen, J | 1 |
Ahmed, AU; Amidei, C; Arrieta, VA; Castro, B; Chang, CL; Chen, L; Cordero, A; Dmello, C; Gould, A; Győrffy, B; Horbinski, C; Hsu, P; Kang, SJ; Kanojia, D; Lesniak, MS; Sonabend, A; Sonabend, AM; Stupp, R; Winter, J; Zhang, DY; Zhang, J | 1 |
Banerjee, R; Chaudhari, P; Chekuri, G; Dutt, S; Gera, P; Goda, J; Mohanty, B; Sandbhor, P; Yadav, S | 1 |
Burek, M; Domröse, D; Ernestus, RI; Förster, CY; Giladi, M; Giniunaite, A; Hagemann, C; Hörmann, J; Kessler, AF; Löhr, M; Salvador, E; Schaeffer, C; Tempel-Brami, C; Volodin, A; Voloshin, T; Zeidan, A | 1 |
Abu-Gharbieh, E; Abuhelwa, AY; Ahmed, M; Alqudah, MAY; Alsoud, LO; Alzoubi, KH; Bustanji, Y; El-Awady, R; El-Huneidi, W; Ramadan, WS; Semreen, AM; Semreen, MH; Shara, M; Soares, NC | 1 |
Ashourpour, M; Kazerouni, F; Mostafavi Hosseini, F; Salami, S; Shahsavari, Z; Taheri, S; Tavakoli Yaraki, M | 1 |
Amerhanova, S; Babaev, V; Buzyurova, D; Gaynanova, G; Kuznetsov, D; Lukashenko, S; Lyubina, A; Pavlov, R; Petrov, K; Romanova, E; Voloshina, A; Zakharova, L; Zueva, I | 1 |
Erthal, LCS; Gobbo, OL; Ruiz-Hernandez, E; Shi, Y; Sweeney, KJ | 1 |
Brem, H; Chakroun, RW; Chen, D; Chen, Z; Cui, H; Gorelick, N; Guan, Y; Hanes, J; Huang, Q; Monroe, MK; Serra, R; Su, H; Suk, JS; Sun, M; Tyler, B; Wang, F; Wang, H; Wang, Z; Zheng, M | 1 |
Decuzzi, P; Di Mascolo, D; Guerriero, I; Palange, AL; Pesce, C; Spanò, R | 1 |
Bachoo, R; Cai, Q; Fan, H; Gao, X; Ge, X; Giannotta, M; Hoyt, K; Li, J; Li, X; Maher, E; Margolis, R; Qin, Z; Vemireddy, V; Xiong, H | 1 |
Dadey, DY; Fitzpatrick, J; Hallahan, DE; Kapoor, V; Rau, MJ; Saikia, M; Shah, HK; Singh, AK; Thotala, D; Townsend, R | 1 |
Alinezhad, A; Behrooz, AB; Davazdahemami, AA; Hamzah, ASA; Homaie, FM; Jamalpour, S; Maddah, SM; Sabah, JT; Vazifehmand, R | 1 |
Guan, J; Qian, J; Zhan, C | 1 |
Schwendeman, SP | 1 |
Caban-Toktas, S; Capan, Y; Dalkara, T; Esendagli, G; Karlı Oguz, K; Khan, M; Lule, S; Mut, M; Sahin, A; Soylemezoglu, F; Vural, I | 1 |
Ainslie, KM; Bachelder, EM; Graham-Gurysh, EG; Hingtgen, SD; Lee, T; Moore, KM; Schorzman, AN; Zamboni, WC | 1 |
Cai, K; Li, K; Lin, C; Lu, L; Luo, Z; Shen, X; Tao, B | 1 |
Banerjee, R; Chaudhuri, A; Jaggarapu, MMCS; Madhusudana, K; Moku, G; Ramkrishna, S; Saha, S; Shankar, G; Srinivas, R; Yakati, V | 1 |
Ge, Y; Liu, Y; Ren, L; Shan, W; Wang, X; Yang, J; Ye, S; Zhang, Q; Zhang, X; Zhou, X | 1 |
Adabi, M; Bergonzi, MC; Esnaashari, SS; Khosravani, M; Madani, F; Webster, TJ; Younes, HM | 1 |
Black, KL; Butte, P; Chung, LWK; Perez, JM; Reichel, D; Sagong, B; Teh, J; Wagner, S; Wang, H; Yu, JS; Zhang, Y | 1 |
Bernstein, AM; Deming, TJ; Garrett, MC; Hung, D; Kornblum, HI; O'Shea, TM; Sofroniew, MV; Soto, H; Staarman, B; Wollenberg, AL | 1 |
Bazzazzadeh, A; Dizaji, BF; Irani, M; Kianinejad, N; Nouri, A | 1 |
Chen, W; Di, Q; Ma, W; Ma, X; Sun, P; Wang, Q; Xiao, Y | 1 |
Guo, Y; Li, D; Li, Z; Su, W; Wang, Y | 1 |
Ghosh, S; Gupta, V; Joseph, MM; Maiti, KK; Maniganda, S; Mohapatra, S; Nair, JB | 1 |
Almaimani, RA; Almasmoum, HA; Alrobaian, M; Baothman, AA; Beg, S; Choudhry, H; Ghaith, MM; Ibrahim, IAA; Panda, SK; Shen, L; Singh, T; Wang, L; Wang, X | 1 |
Adabi, M; Ghanbari, H; Hadjighassem, MR; Hosseini Najafabadi, MR; Khosravani, M; Maleki, H; Sadroddiny, E; Webster, TJ | 1 |
Ali, J; Baboota, S; Mittal, S | 1 |
Behrooz, AB; Masarudin, MJ; Masomian, M; Sekawi, Z; Syahir, A; Tajudin, AA; Vazifehmand, R | 1 |
Chang, CW; Chen, HH; Chiang, CS; Chiang, WH; Chiu, HC; Huang, WC; Lin, YW; Lu, IL; Tsai, YC | 1 |
Alessandri, G; Benetti, A; Berenzi, A; Cadei, M; Ceserani, V; Ciusani, E; Ferri, A; Ferroli, P; Finocchiaro, G; Pallini, R; Parati, E; Pessina, A; Restelli, F; Schiariti, MP | 1 |
Alessandri, G; Aralla, M; Bonomi, A; Brini, AT; Ceserani, V; Coccè, V; Ghezzi, E; Guercio, A; Parati, E; Pascucci, L; Pessina, A; Pettinari, L; Zeira, O | 1 |
Chen, S; Chen, X; Diao, X; Hu, Y; Pi, Z; Shen, Y; Yan, F; Yeh, CK; Zeng, X; Zheng, H | 1 |
Fu, J; Jiang, Y; Lv, L; Wang, X; Xin, H; Yao, Q; Zhang, Q | 1 |
Gao, L; Han, L; Lu, W; Nan, L; Peng, T; Sun, L; Wang, J; Wang, Y; Yan, Z; Yu, J; Yu, L; Zhang, L; Zhao, S; Zhou, J | 1 |
Auslander, N; Ben-Shushan, D; Calderón, M; Eldar-Boock, A; Ferber, S; Grossman, R; Haag, R; Henkin, J; Krivitsky, A; Licha, K; Ofek, P; Ram, Z; Ruppin, E; Satchi-Fainaro, R; Scomparin, A; Sousa-Herves, A; Tiram, G; Vossen, LI; Yeini, E | 1 |
Chang, KR; Ihsan, A; Javed, I; Madni, A; Rehman, M; Shi, D; Tahir, N; Webster, TJ | 1 |
Hu, Y; Jiang, T; Jiang, X; Jin, K; Liu, X; Luo, Z; Pang, Z; Shen, S; Tuo, Y; Wang, H; Zhang, B | 1 |
Fisusi, FA; Schätzlein, AG; Uchegbu, IF | 1 |
Jiang, P; Li, Y; Liu, X; Tang, C; Wu, M; Yan, F; Zhang, N; Zheng, H | 1 |
Bastiancich, C; Bianco, J; Danhier, F; Gallez, B; Ganipineni, LP; Jankovski, A; Joudiou, N; Préat, V; Rieux, AD; Tsakiris, N; Zhao, M | 1 |
Hong, SP; Kang, BS; Kang, SH | 1 |
Bastiancich, C; Bianco, J; Danhier, F; Danhier, P; Gallez, B; Ganipineni, LP; Joudiou, N; Préat, V; Ucakar, B; Zhao, M | 1 |
Borrós, S; Brugada Vilà, P; Cascante, A; Di Mauro, PP; Gómez-Vallejo, V; Llop, J | 1 |
Bastiancich, C; Bastiat, G; Bozzato, E; Danhier, F; Luyten, U; Préat, V | 1 |
Altshuler, D; Castro, MG; Doherty, R; Edwards, M; Kadiyala, P; Kamran, N; Kuai, R; Li, D; Lowenstein, PR; Moon, JJ; Nuñez, FM; Schwendeman, A; Yu, M | 1 |
Braidy, N; Günaydın, C; Nazıroğlu, M; Öztürk, Y; Yalçın, F | 1 |
Chakroun, RW; Cui, H; Lin, R; Pompa, D; Su, H; Wang, F; Wang, Y | 1 |
Asser, T; Bergers, G; Bjerkvig, R; Friedmann-Morvinski, D; Hunt, H; Kotamraju, VR; Lingasamy, P; Mastandrea, I; Paiste, P; Rätsep, T; Rousso-Noori, L; Ruoslahti, E; Säälik, P; Simón-Gracia, L; Teesalu, T; Tobi, A; Toome, K | 1 |
Bozzato, E; Danhier, F; Gallez, B; Ghiassinejad, S; Joudiou, N; Préat, V; Zhao, M | 1 |
Ahmadi-Zeidabadi, M; Esmaeeli, M; Forootanfar, H; Pardakhty, A; Pournamdari, M; Salarpour, S | 1 |
Cai, X; Fu, W; Li, S; Lin, S; Lin, Y; Shao, X; Shi, S; Tang, Z; Tian, T; Zhang, T; Zhang, Y; Zhou, Y | 1 |
Barazas, M; De Witt Hamer, PC; Geerts, D; Gray, NS; Hagemann, C; Hiddingh, L; Kerami, M; Kessler, AF; Kwiatkowski, N; Lagerweij, T; Lewandrowski, G; Niers, JM; Nilsson, RJ; Noske, DP; Sol, N; Tannous, BA; Van der Stoop, PM; Van Tellingen, O; Vandertop, WP; Wang, J; Wedekind, L; Würdinger, T; Zhou, W | 1 |
Kim, SS; Kim, SY; Lim, SH; Seong, S | 1 |
Brons, S; Combs, SE; Debus, J; Haberer, T; Schlaich, F; Weber, KJ | 1 |
Borrós, S; Di Mauro, PP | 1 |
Gao, Y; Hedstrom, L; Kuang, Y; Long, MJ; Shi, J; Xu, B; Xu, C; Zhou, J | 1 |
Gao, H; Jiang, X; Pang, Z; Qian, Y; Wei, Y; Wu, J; Yang, Z; Yu, Y; Zhang, B; Zhao, J | 1 |
Annovazzi, L; Battaglia, L; Biasibetti, E; Caldera, V; Capucchio, MT; Chirio, D; Corona, S; Filice, G; Gallarate, M; Lanotte, M; Mellai, M; Muntoni, E; Panciani, P; Peira, E; Riganti, C; Schiffer, D; Valazza, A | 1 |
Alessandri, G; Bonomi, A; Cavicchini, L; Ciusani, E; Coccè, V; Dossena, M; Frigerio, S; Lisini, D; Mantegazza, R; Marfia, G; Navone, SE; Parati, E; Pessina, A; Rampini, P; Rimoldi, M; Rizzetto, M; Sisto, F | 1 |
Agrawal, U; Chashoo, G; Kumar, A; Saxena, AK; Sharma, PR; Vyas, SP | 1 |
Annovazzi, L; Battaglia, L; Caldera, V; Chirio, D; Melcarne, A; Mellai, M; Riganti, C; Schiffer, D | 1 |
Annovazzi, L; Biunno, I; Cassoni, P; Cattaneo, M; De Blasio, P; Melcarne, A; Mellai, M; Schiffer, D; Storaci, AM | 1 |
Chen, Q; Feng, L; Li, Y; Liu, Z; Wang, C; Wang, X | 1 |
Chen, H; Chen, J; Feng, X; Gao, X; Jiang, D; Jiang, M; Kang, T; Song, Q; Yao, J | 1 |
Chen, J; Feng, X; Gao, X; Jiang, D; Jiang, X; Jing, Y; Kang, T; Liang, J; Song, Q; Yao, J | 1 |
Bade, D; Bicker, U; Bludszuweit-Philipp, C; Geltmeier, A; Maier, P; Meditz, K; Rinner, B; Witt, R | 1 |
Benoit, JP; Couez, D; Franconi, F; Lemaire, L; Lollo, G; Ullio-Gamboa, G; Vincent, M | 1 |
Alessandri, G; Bonomi, A; Coccè, V; D'Alessandris, QG; De Pascalis, I; Falchetti, ML; Giannetti, S; Morgante, L; Pacioni, S; Pallini, R; Pascucci, L; Pessina, A | 1 |
Jiang, Y; Liu, X; Lv, L; Lv, W; Wang, B; Wang, Z; Xin, H; Xu, Q; Zhao, Y | 1 |
Boxerman, J; Coyle, T; DiPetrillo, T; Donahue, JE; Elinzano, H; Evans, D; Glantz, M; Hebda, N; Kesari, S; Kim, L; Mantripragada, K; Mitchell, KM; Mrugala, M; Pan, E; Piccioni, DE; Rosati, KL; Safran, H; Timothy, K; Yunus, S | 1 |
Duan, Y; Gao, P; Shen, M; Sun, Y; Xu, Y | 1 |
Duan, Y; Li, Y; Shen, M; Sun, Y; Teng, Y; Wang, Y; Xu, Y | 1 |
Chen, J; Feng, J; Feng, X; Gao, X; Jiang, D; Jiang, T; Jiang, X; Jing, Y; Kang, T; Song, Q; Yao, J; Zhu, Q | 1 |
Castro, MG; Doherty, R; Lowenstein, PR; Wilson, TJ; Zamler, DB | 1 |
Jiang, T; Jiang, X; Jin, K; Liu, X; Lu, H; Luo, Z; Pang, Q; Pang, Z; Yan, Z; Yu, L | 1 |
Mu, Q; Stephen, ZR; Wang, H; Wang, K; Yu, Y; Zhang, M; Zhou, S | 1 |
Alessandri, G; Bonomi, A; Buccarelli, M; Coccè, V; D'Alessandris, QG; Falchetti, ML; Giannetti, S; Morgante, L; Pacioni, S; Pallini, R; Pascucci, L; Pessina, A; Ricci-Vitiani, L | 1 |
Chang, KC; Eun, SY; Ham, SA; Han, CW; Jang, HS; Kim, HJ; Kim, JH; Lee, JH; Seo, HG; Woo, IS | 1 |
Banik, NL; Ray, SK; Zhang, R | 1 |
Banik, NL; Butler, JT; Janardhanan, R; Ray, SK | 1 |
Lee, HS; Lee, LY; Lu, F; Ong, BY; Ranganath, SH; Sahinidis, NV; Wang, CH | 1 |
Banik, NL; George, J; Ray, SK | 2 |
Benoit, JP; Garcion, E; Jarnet, D; Menei, P; Paillard, A; Vinchon-Petit, S | 1 |
Dicker, DT; Dorsey, JF; Dowling, ML; El-Deiry, WS; Kao, GD; Mintz, A; Plastaras, JP; Tian, X | 1 |
Gu, B; Li, J; Liu, Y; Lu, W; Xie, C; Zhan, C | 1 |
Han, L; Jia, ZF; Kang, CS; Mei, M; Pu, PY; Ren, Y; Wang, GX; Xu, P; Yuan, XB; Zhou, X | 1 |
Chang, KC; Eun, SY; Hong, SC; Kang, ES; Kim, HJ; Kim, JH; Lee, JH; Seo, HG; Woo, IS | 1 |
Arifin, DY; Chow, PK; Fu, Y; Kee, I; Lee, HS; Ranganath, SH; Wang, CH; Zheng, L | 1 |
Chen, L; Chen, Y; Fang, X; Gu, J; Jiang, X; Luo, J; Ren, X; Sha, X; Wei, Z; Xin, H | 1 |
Andelković, T; Banković, J; Pešić, M; Podolski-Renić, A; Ruždijić, S; Tanić, N | 1 |
Banik, NL; Karmakar, S; Ray, SK; Roy Choudhury, S | 1 |
Chen, L; Chen, Y; Fang, X; Gu, J; Jiang, X; Jiang, Y; Law, K; Sha, X; Wang, X; Xin, H | 1 |
Anelli, V; Bassi, R; Brioschi, L; Campanella, R; Caroli, M; De Zen, F; Gaini, SM; Giussani, P; Riboni, L; Riccitelli, E; Viani, P | 1 |
Ding, D; Guo, H; Hu, H; Jiang, L; Lu, L; Ma, W; Meng, W; Xiao, K; Yu, H; Zheng, W | 1 |
Brons, S; Combs, SE; Debus, J; Haberer, T; Habermehl, D; Rieken, S; Weber, KJ; Winter, M; Zipp, L | 1 |
Battastini, AM; Braganhol, E; Moreira, JC; Zanotto-Filho, A | 1 |
Feng, L; Lu, W; Qian, J; Wei, X; Zhan, C; Zhu, J | 1 |
Chang, HY; Chang, MW; Chuang, CY; Juan, HF; Lo, JM | 1 |
Behe, M; Braun, F; Grosu, AL; Milanović, D; Niedermann, G; Weber, W | 1 |
Chen, L; Fang, X; Jiang, X; Sha, X; Xin, H; Zhang, W | 1 |
Banik, NL; Hossain, M; Ray, SK | 1 |
Banerjee, R; Joshi, N; Shanmugam, T; Thakur, A | 1 |
Chen, H; Chen, J; Gao, X; Gu, G; Hu, Q; Jiang, M; Kang, T; Liu, Z; Miao, D; Pang, Z; Song, Q; Tu, Y; Xia, H; Yao, L | 1 |
Baumann, BC; Chapman, C; Discher, DE; Dorsey, JF; Harada, T; Kao, GD; Mahmud, A; Swift, J; Xu, X | 1 |
Balzeau, J; Benoit, JP; Berges, R; Eyer, J; Pinier, M; Saulnier, P | 1 |
Eichler, HG; Guensberg, P; Jansen, B; Lucas, T; Monia, B; Pehamberger, H; Wacheck, V | 1 |
Bauer, B; Bernhardt, G; Buschauer, A; Fankhänel, M; Färber, L; Fellner, S; Fricker, G; Graeff, C; Gschaidmeier, H; Miller, DS; Schaffrik, M; Spruss, T | 1 |
Dicker, AP; Grant, DS; Williams, TL; Zahaczewsky, M | 1 |
Baayen, HC; Barkhof, F; Boogerd, W; Castelijns, JA; Elkhuizen, PH; Heimans, JJ; Postma, TJ; Uitdehaag, BM; Vos, MJ | 1 |
Bombardelli, E; Cassinelli, G; D'Incalci, M; Frapolli, R; Laccabue, D; Lanzi, C; Morazzoni, P; Pratesi, G; Riva, A; Supino, R; Zucchetti, M; Zunino, F | 1 |
Faibel, M; Hadani, M; Jonas, T; Lidar, Z; Mardor, Y; Nass, D; Pfeffer, R; Ram, Z | 1 |
Atherton, JA; Baker, DA; Barth, W; Cohen, BD; Cooper, B; Dalvie, D; Hungerford, W; Kath, JC; Lin, J; Lyssikatos, JP; Moraski, G; Pollack, V; Ralston, S; Roberts, WG; Savage, D; Soderstrom, C; Soderstrom, E; Szewc, R; Tkalcevic, G; Ung, E; Wang, HF; Whalen, PM | 1 |
Cromwell, LD; Fadul, CE; Kingman, LS; McDonnell, CE; Meyer, LP; Pipas, JM; Rhodes, CH; Rigas, JR | 1 |
Gildehaus, FJ; Goldbrunner, R; Holtmannspötter, M; Kreth, FW; Pöpperl, G; Tanner, P; Tatsch, K; Tonn, JC | 1 |
Kiwit, JC; Kratzel, C; Patt, S; Reszka, R; von Eckardstein, KL | 1 |
Kiwit, JC; Reszka, R; von Eckardstein, KL | 1 |
Groves, MD; Jeon, JW; Kang, CM; Kim, JH; Kim, JT; Kim, MH; Kim, YJ; Nam, DH; Park, K; Park, SY; Son, MJ; Song, HS | 1 |
Bernhardt, G; Buschauer, A; Gartner, M; Giannis, A; Gross, D; Müller, C; Sarli, V | 1 |
Baraldi, PG; Benini, A; Borea, PA; Gessi, S; Leung, E; Maclennan, S; Merighi, S; Mirandola, P; Varani, K | 1 |
Baas, PW; Bertrand, L; de Chadarévian, JP; Dráber, P; Dráberová, E; Katsetos, CD; Legido, A; Nissanov, J; Reddy, G; Smejkalová, B | 1 |
Banik, NL; Das, A; Ray, SK | 2 |
Banik, NL; Karmakar, S; Patel, SJ; Ray, SK | 1 |
Budinger, TF; Forte, TM; Gibbs, AR; Hunt, CA; Nikanjam, M | 1 |
Banik, NL; Karmakar, S; Ray, SK | 1 |
Aldape, K; Aoki, H; Bogler, O; Conrad, C; Hess, K; Hollingsworth, EF; Iwado, E; Kobayashi, R; Kondo, S; Kondo, Y; Mills, G; Sawaya, R; Shingu, T; Shinojima, N; Tamada, Y; Yamamoto, A; Yokoyama, T; Zhang, L | 1 |
Akerley, W; Choy, H; Egorin, MJ; Glantz, MJ; Kearns, CM | 1 |
Close, LG; Fathallah-Skaykh, H; Gazdar, AF; Griener, J; Kamen, B; Lucci, JA; Rosenthal, DI; Schold, SC; Truelson, J; Vuitch, FM | 1 |
Chicoine, MR; Madsen, CL; Silbergeld, DL | 1 |
Ainsworth, S; Helson, C; Helson, L; Malik, S; Mangiardi, J | 1 |
Choy, H; Cole, BF; Egorin, MJ; Glantz, MJ; Kearns, CM; Mills, P; Rhodes, CH; Saris, S; Stopa, E; Zuhowski, EG | 1 |
Jones, KD | 1 |
Carbone, DP; Fathallah-Shaykh, H; Gazdar, AF; Griener, J; Hamilton, L; Landay, M; McWhorter, J; Mendelsohn, D; Okani, O; Orr, KY; Rosenthal, DI; Tourville, J; Truelson, JM; Vuitch, FM | 1 |
Burt, HM; Davis, NL; Demetrick, JS; Hunter, WL; Liggins, RT; Machan, L | 1 |
Arnold, H; Bjerkvig, R; Dahl, O; Gundersen, G; Heese, O; Terzis, AJ; Thorsen, F; Visted, T | 1 |
Erlanger, B; Fetell, MR; Fisher, JD; Grossman, SA; Piantadosi, S; Rowinsky, E; Stockel, J | 1 |
Arbit, E; Lederman, G; Lombardi, E; Odaimi, M; Wronski, M; Wrzolek, M | 1 |
Arbit, E; Lederman, G; Lombardi, E; Odaimi, M; Wertheim, S | 1 |
Georgoulias, V; Giatromanolaki, A; Kakolyris, S; Koukourakis, MI; Schiza, S | 1 |
Cordes, N; Plasswilm, L; Sauer, R | 1 |
Boucher, Y; Brekken, C; Griffon-Etienne, G; Jain, RK; Suit, HD | 1 |
Chamberlain, MC; Kormanik, P | 1 |
Agarwal, S; Awasthy, BS; Julka, PK; Mahapatra, AK; Rath, GK; Singh, R; Varna, T | 1 |
Arbit, E; Lederman, G; Lombardi, E; Odaimi, M; Wertheim, S; Wronski, M; Wrzolek, M | 1 |
Capizzello, A; Foroglou, G; Fountzilas, G; Kalogera-Fountzila, A; Karavelis, A; Karkavelas, G; Selviaridis, P; Tourkantonis, A; Zamboglou, N | 1 |
Beenen, LF; Heimans, JJ; Hoekstra, OS; Klein, M; Luykx, SA; Postma, TJ; Taphoorn, MJ; van Groeningen, CJ; Vermorken, JB; Zonnenberg, BA | 1 |
Finlay, J; Glass, J; Gruber, ML; Hochster, H; Muggia, FM; Nirenberg, A; Rosenthal, MA | 1 |
Burt, HM; D'Amours, S; Demetrick, JS; Liggins, RT; Machan, LS | 1 |
Ikeda, J | 1 |
Curran, W; Langer, CJ; Movsas, B; Murray, K; Paulus, R; Rhodes, H; Ruffer, J | 1 |
Frankel, LS; Liu, L; Munoz, LK; Rosenthal, DI; Strauss, LC; Vapiwala, N; Weitman, S; Winick, NJ | 1 |
Horowitz, J | 1 |
Bernhardt, G; Buschauer, A; Göpferich, A; Spruss, T; Vogelhuber, W | 1 |
2 review(s) available for paclitaxel and Astrocytoma, Grade IV
Article | Year |
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Overcoming the Challenges in the Treatment of Glioblastoma via Nanocarrier- based Drug Delivery Approach.
Topics: Adult; Brain; Brain Neoplasms; Drug Delivery Systems; Glioblastoma; Humans; Paclitaxel | 2021 |
Adenovirus-mediated p53 gene therapy: overview of preclinical studies and potential clinical applications.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Combined Modality Therapy; Drug Resistance, Neoplasm; Female; Genes, p53; Genetic Therapy; Genetic Vectors; Glioblastoma; Head and Neck Neoplasms; Humans; Injections; Interleukin-2; Liver Neoplasms; Lung Neoplasms; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Neoplasms; Ovarian Neoplasms; Paclitaxel; Radiotherapy, Adjuvant; Recombinant Fusion Proteins; Salvage Therapy; Signal Transduction; Treatment Outcome; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 1999 |
18 trial(s) available for paclitaxel and Astrocytoma, Grade IV
Article | Year |
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PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation: A Randomized Phase II Study: BrUOG 244.
Topics: Academic Medical Centers; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Follow-Up Studies; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Paclitaxel; Polyglutamic Acid; Radiotherapy, Adjuvant; Single-Blind Method; Survival Analysis; Treatment Outcome; Tumor Suppressor Proteins; United States | 2018 |
Convection-enhanced delivery of paclitaxel for the treatment of recurrent malignant glioma: a phase I/II clinical study.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Combined Modality Therapy; Convection; Diffusion Magnetic Resonance Imaging; Dose-Response Relationship, Drug; Female; Frontal Lobe; Glioblastoma; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Parietal Lobe; Prospective Studies; Temporal Lobe | 2004 |
A Phase II trial of paclitaxel and topotecan with filgrastim in patients with recurrent or refractory glioblastoma multiforme or anaplastic astrocytoma.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Filgrastim; Glioblastoma; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Recombinant Proteins; Thrombocytopenia; Topotecan; Treatment Outcome | 2005 |
O-(2-[18F]fluoroethyl)-L-tyrosine PET for monitoring the effects of convection-enhanced delivery of paclitaxel in patients with recurrent glioblastoma.
Topics: Antineoplastic Agents; Brain Neoplasms; Convection; Drug Delivery Systems; Female; Glioblastoma; Humans; Infusions, Intralesional; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Tyrosine | 2005 |
Weekly, outpatient paclitaxel and concurrent cranial irradiation in adults with brain tumors: preliminary results and promising directions.
Topics: Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Female; Glioblastoma; Humans; Karnofsky Performance Status; Male; Middle Aged; Nervous System Diseases; Paclitaxel; Premedication; Radiation-Sensitizing Agents; Regression Analysis; Survival Rate | 1995 |
Phase I studies of continuous-infusion paclitaxel given with standard aggressive radiation therapy for locally advanced solid tumors.
Topics: Anemia; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Cycle; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Glioblastoma; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Lymphopenia; Paclitaxel; Radiation-Sensitizing Agents; Remission Induction; Uterine Cervical Neoplasms | 1995 |
Phase I study of weekly outpatient paclitaxel and concurrent cranial irradiation in adults with astrocytomas.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Glioblastoma; Humans; Middle Aged; Paclitaxel | 1996 |
Intensive radiation therapy concurrent with up to 7-week continuous-infusion paclitaxel for locally advanced solid tumors: phase I studies.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Glioblastoma; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Paclitaxel; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Survival Analysis | 1997 |
Preirradiation paclitaxel in glioblastoma multiforme: efficacy, pharmacology, and drug interactions. New Approaches to Brain Tumor Therapy Central Nervous System Consortium.
Topics: Aged; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Chemotherapy, Adjuvant; Drug Interactions; Female; Glioblastoma; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm, Residual; Paclitaxel; Radiotherapy, Adjuvant; Survival Analysis; Time Factors; Treatment Outcome | 1997 |
Concurrent twice-a-week docetaxel and radiotherapy: a dose escalation trial with immunological toxicity evaluation.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Docetaxel; Dose Fractionation, Radiation; Drug Administration Schedule; Feasibility Studies; Female; Glioblastoma; Humans; Lung Neoplasms; Lymphocytes; Lymphopenia; Male; Middle Aged; Neoplasms; Neutropenia; Paclitaxel; Pelvic Neoplasms; Radiation-Sensitizing Agents; Radiotherapy; Survival Analysis; Taxoids; Treatment Outcome | 1999 |
Salvage chemotherapy with taxol for recurrent anaplastic astrocytomas.
Topics: Adult; Antineoplastic Agents, Phytogenic; Combined Modality Therapy; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Salvage Therapy | 1999 |
A study of concurrent radiochemotherapy with paclitaxel in glioblastoma multiforme.
Topics: Brain Neoplasms; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm, Residual; Paclitaxel; Prognosis; Radiation-Sensitizing Agents; Survival Rate | 2000 |
Treatment of recurrent glioblastoma multiforme using fractionated stereotactic radiosurgery and concurrent paclitaxel.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Combined Modality Therapy; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Radiosurgery; Survival Analysis; Treatment Outcome | 2000 |
Radiation and concomitant weekly administration of paclitaxel in patients with glioblastoma multiforme. A phase II study.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Combined Modality Therapy; Disease Progression; Female; Glioblastoma; Humans; Male; Middle Aged; Paclitaxel; Radiotherapy; Survival Analysis; Time Factors | 1999 |
A phase II study of paclitaxel in chemonaïve patients with recurrent high-grade glioma.
Topics: Adult; Affect; Aged; Antineoplastic Agents, Phytogenic; Astrocytoma; Brain Neoplasms; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Prospective Studies; Quality of Life; Survival Analysis; Treatment Outcome | 2000 |
Phase II study of combination taxol and estramustine phosphate in the treatment of recurrent glioblastoma multiforme.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Drug Therapy, Combination; Estramustine; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Treatment Outcome | 2000 |
Phase II radiation therapy oncology group trial of weekly paclitaxel and conventional external beam radiation therapy for supratentorial glioblastoma multiforme.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Combined Modality Therapy; Drug Administration Schedule; Feasibility Studies; Female; Glioblastoma; Humans; Male; Middle Aged; Paclitaxel; Radiation-Sensitizing Agents; Supratentorial Neoplasms | 2001 |
A phase I study of cranial radiation therapy with concomitant continuous infusion paclitaxel in children with brain tumors.
Topics: Adolescent; Brain; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Drug Administration Schedule; Female; Follow-Up Studies; Glioblastoma; Glioma; Humans; Infusions, Intravenous; Male; Paclitaxel; Radiation Injuries; Radiation-Sensitizing Agents; Radiotherapy, High-Energy; Survival Analysis; Treatment Outcome | 2001 |
142 other study(ies) available for paclitaxel and Astrocytoma, Grade IV
Article | Year |
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Oxaphosphinanes: new therapeutic perspectives for glioblastoma.
Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Survival; Cyclic P-Oxides; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Organophosphonates; Phosphorous Acids; Rats; Stereoisomerism; Structure-Activity Relationship | 2012 |
Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma.
Topics: Brain Neoplasms; Glioblastoma; Humans; Phosphorylation; Protein Kinases; Structure-Activity Relationship; Tyrosine | 2017 |
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A.
Topics: Antineoplastic Agents; Apoptosis; Biological Products; Brain Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glioblastoma; Goosecoid Protein; Humans; Molecular Structure; Saponins; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
Temperature and pH-responsive in situ hydrogels of gelatin derivatives to prevent the reoccurrence of brain tumor.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Gelatin; Glioblastoma; Humans; Hydrogels; Hydrogen-Ion Concentration; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; Paclitaxel; Porosity; Stimuli Responsive Polymers; Sulfamethazine; Temperature; Time Factors; Viscosity; Xenograft Model Antitumor Assays | 2021 |
Surface Modification of Nanoparticles Enhances Drug Delivery to the Brain and Improves Survival in a Glioblastoma Multiforme Murine Model.
Topics: Animals; Brain; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Glioblastoma; Humans; Lactic Acid; Mice; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution | 2022 |
Iron oxide nanoparticles loaded with paclitaxel inhibits glioblastoma by enhancing autophagy-dependent ferroptosis pathway.
Topics: Animals; Autophagy; Cell Line, Tumor; Ferroptosis; Glioblastoma; Humans; Magnetic Iron Oxide Nanoparticles; Mice; Nanoparticles; Paclitaxel | 2022 |
Translocon-associated Protein Subunit SSR3 Determines and Predicts Susceptibility to Paclitaxel in Breast Cancer and Glioblastoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Pharmacological; Brain Neoplasms; Breast Neoplasms; Calcium-Binding Proteins; Cell Line, Tumor; Drug Resistance, Neoplasm; Endoribonucleases; Female; Glioblastoma; Humans; Membrane Glycoproteins; Mice; Paclitaxel; Prospective Studies; Protein Serine-Threonine Kinases; Receptors, Cytoplasmic and Nuclear; Receptors, Peptide; Xenograft Model Antitumor Assays | 2022 |
Targeted nano-delivery of chemotherapy via intranasal route suppresses in vivo glioblastoma growth and prolongs survival in the intracranial mouse model.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Glioma; Mice; Mice, Inbred NOD; Mice, SCID; Nanoparticles; Paclitaxel; Transferrin | 2023 |
Tumor Treating Fields (TTFields) Reversibly Permeabilize the Blood-Brain Barrier In Vitro and In Vivo.
Topics: Animals; Blood-Brain Barrier; Claudin-5; Endothelial Cells; Glioblastoma; Mice; Paclitaxel; Rats; rho-Associated Kinases | 2022 |
Metabolomics Analysis Revealed Significant Metabolic Changes in Brain Cancer Cells Treated with Paclitaxel and/or Etoposide.
Topics: Brain Neoplasms; Etoposide; Glioblastoma; Humans; Paclitaxel; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2022 |
Novel Derivatives of Tetrahydrobenzo (g) Imidazo[α-1,2] Quinoline Induce Apoptosis Via ROS Production in the Glioblastoma Multiforme Cells, U-87MG.
Topics: Apoptosis; Glioblastoma; Humans; Paclitaxel; Quinolones; Reactive Oxygen Species | 2022 |
The Formation of Morphologically Stable Lipid Nanocarriers for Glioma Therapy.
Topics: Animals; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Lipids; Liposomes; Paclitaxel; Rats; Rats, Wistar | 2023 |
Nanocomposite formulation for a sustained release of free drug and drug-loaded responsive nanoparticles: an approach for a local therapy of glioblastoma multiforme.
Topics: Adult; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Glioblastoma; Humans; Hydrogels; Nanocomposites; Nanoparticles; Neoplasm Recurrence, Local; Paclitaxel; Temozolomide | 2023 |
Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma.
Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Hydrogels; Immunotherapy; Neoplasm Recurrence, Local; Paclitaxel; Tumor Microenvironment; Tumor-Associated Macrophages | 2023 |
μMESH-Enabled Sustained Delivery of Molecular and Nanoformulated Drugs for Glioblastoma Treatment.
Topics: Animals; Cell Line, Tumor; Docetaxel; Glioblastoma; Nanoparticles; Paclitaxel; Pharmaceutical Preparations; Polymers; Polyvinyl Alcohol | 2023 |
Optical blood-brain-tumor barrier modulation expands therapeutic options for glioblastoma treatment.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Female; Glioblastoma; Gold; Humans; Metal Nanoparticles; Mice; Nanoparticles; Paclitaxel | 2023 |
Blocking the functional domain of TIP1 by antibodies sensitizes cancer to radiation therapy.
Topics: Animals; Antibodies; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Glioblastoma; Humans; Lung Neoplasms; Mice; Paclitaxel | 2023 |
Modulating Wnt/β-Catenin Signaling Pathway on U251 and T98G Glioblastoma Cell Lines Using a Combination of Paclitaxel and Temozolomide, A Molecular Docking Simulations and Gene Expression Study.
Topics: beta Catenin; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression; Glioblastoma; Glycogen Synthase Kinase 3 beta; Humans; Molecular Docking Simulation; Paclitaxel; Temozolomide; Wnt Signaling Pathway | 2023 |
Preparation of Cholera Toxin Subunit B Functionalized Nanoparticles for Targeted Therapy of Glioblastoma.
Topics: Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; Brain Neoplasms; Cholera Toxin; Drug Carriers; Glioblastoma; Glycosphingolipids; Microscopy, Electron, Transmission; Nanoparticles; Neovascularization, Pathologic; Paclitaxel; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer | 2020 |
A local combination therapy to inhibit GBM recurrence.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Carriers; Drug Delivery Systems; Glioblastoma; Humans; Hydrogels; Neoplasm Recurrence, Local; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Temozolomide | 2019 |
Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Combinations; Drug Liberation; Female; Flurbiprofen; Glioblastoma; Nanoparticles; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Tumor Burden | 2020 |
Tumor Responsive and Tunable Polymeric Platform for Optimized Delivery of Paclitaxel to Treat Glioblastoma.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dextrans; Drug Carriers; Drug Liberation; Female; Glioblastoma; Humans; Hydrogen-Ion Concentration; Mice, Nude; Neoplasm Metastasis; Paclitaxel; Polyesters; Secondary Prevention; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2020 |
The nanoparticle-facilitated autophagy inhibition of cancer stem cells for improved chemotherapeutic effects on glioblastomas.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Line; Cell Survival; Chloroquine; Drug Delivery Systems; Folic Acid; Glioblastoma; Humans; Mice; Nanoparticles; Neoplastic Stem Cells; Paclitaxel; Serum Albumin, Bovine | 2019 |
Amphetamine decorated cationic lipid nanoparticles cross the blood-brain barrier: therapeutic promise for combating glioblastoma.
Topics: Amphetamine; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cations; Cell Proliferation; Cell Survival; Drug Delivery Systems; Drug Liberation; Drug Screening Assays, Antitumor; Female; Glioblastoma; Lipids; Mice; Mice, Inbred C57BL; Molecular Structure; Nanoparticles; Paclitaxel; Particle Size; RNA, Small Interfering; Surface Properties; Tumor Cells, Cultured | 2020 |
Nanoparticle-based co-delivery of siRNA and paclitaxel for dual-targeting of glioblastoma.
Topics: Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Humans; Nanoparticles; Paclitaxel; RNA, Small Interfering | 2020 |
Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation.
Topics: Animals; Antineoplastic Agents; Apolipoproteins; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Compounding; Drug Liberation; Endocytosis; Glioblastoma; Hemolysis; Humans; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Methotrexate; Nanoparticles; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Proto-Oncogene Proteins c-bcl-2; Rats | 2020 |
Near Infrared Fluorescent Nanoplatform for Targeted Intraoperative Resection and Chemotherapeutic Treatment of Glioblastoma.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Mice; Nanoparticles; Paclitaxel | 2020 |
Injectable diblock copolypeptide hydrogel provides platform to deliver effective concentrations of paclitaxel to an intracranial xenograft model of glioblastoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Central Nervous System; Drug Carriers; Glioblastoma; Humans; Hydrogels; Mice; Mice, Inbred NOD; Mice, SCID; Paclitaxel; Peptides; Survival Rate; Temozolomide; Xenograft Model Antitumor Assays | 2020 |
Fabrication of poly(acrylic acid) grafted-chitosan/polyurethane/magnetic MIL-53 metal organic framework composite core-shell nanofibers for co-delivery of temozolomide and paclitaxel against glioblastoma cancer cells.
Topics: Acrylic Resins; Cell Line, Tumor; Chitosan; Glioblastoma; Humans; Magnetic Phenomena; Metal-Organic Frameworks; Nanofibers; Paclitaxel; Polyurethanes; Temozolomide | 2020 |
Transferrin Receptor-Targeted PEG-PLA Polymeric Micelles for Chemotherapy Against Glioblastoma Multiforme.
Topics: Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Endothelial Cells; Glioblastoma; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Micelles; Paclitaxel; Peptides; Polyethylene Glycols; Receptors, Transferrin; Xenograft Model Antitumor Assays | 2020 |
Evaluation of hepatic drug-metabolism for glioblastoma using liver-brain chip.
Topics: Astrocytes; Blood-Brain Barrier; Brain; Capecitabine; Coculture Techniques; Endothelial Cells; Glioblastoma; Hep G2 Cells; Humans; Inactivation, Metabolic; Lab-On-A-Chip Devices; Liver; Nanoparticles; Paclitaxel; Temozolomide | 2021 |
Tracking the Footprints of Paclitaxel Delivery and Mechanistic Action via SERS Trajectory in Glioblastoma Cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Humans; Paclitaxel | 2020 |
Paclitaxel and naringenin-loaded solid lipid nanoparticles surface modified with cyclic peptides with improved tumor targeting ability in glioblastoma multiforme.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Drug Liberation; Estrogen Antagonists; Female; Flavanones; Glioblastoma; Lipids; Male; Nanoparticles; Paclitaxel; Particle Size; Peptides, Cyclic; Rats; Rats, Wistar | 2021 |
Effect of Paclitaxel/etoposide co-loaded polymeric nanoparticles on tumor size and survival rate in a rat model of glioblastoma.
Topics: Animals; Cell Line, Tumor; Drug Carriers; Etoposide; Glioblastoma; Nanoparticles; Paclitaxel; Polyethylene Glycols; Rats; Survival Rate | 2021 |
Tailoring drug co-delivery nanosystem for mitigating U-87 stem cells drug resistance.
Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dendrimers; Drug Resistance; Drug Resistance, Neoplasm; Glioblastoma; Humans; Paclitaxel; Stem Cells; Temozolomide | 2022 |
Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma.
Topics: Adipocytes; Animals; Antineoplastic Agents; Biological Transport; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Dacarbazine; Drug Carriers; Drug Liberation; Glioblastoma; Humans; Lactic Acid; Magnetite Nanoparticles; Male; Mice, Inbred C57BL; Molecular Targeted Therapy; Oleic Acid; Paclitaxel; Particle Size; Permeability; Polyglutamic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stem Cells; Surface Properties; Temozolomide; Tissue Distribution | 2017 |
Fibronectin-adherent peripheral blood derived mononuclear cells as Paclitaxel carriers for glioblastoma treatment: An in vitro study.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Coculture Techniques; Drug Carriers; Drug Delivery Systems; Fibronectins; Glioblastoma; Humans; Leukocytes, Mononuclear; Middle Aged; Paclitaxel | 2017 |
Effect of canine mesenchymal stromal cells loaded with paclitaxel on growth of canine glioma and human glioblastoma cell lines.
Topics: Adipose Tissue; Animals; Antineoplastic Agents, Phytogenic; Bone Marrow Cells; Cell Line, Tumor; Dogs; Drug Delivery Systems; Glioblastoma; Glioma; Humans; Mesenchymal Stem Cells; Paclitaxel | 2017 |
Enhanced delivery of paclitaxel liposomes using focused ultrasound with microbubbles for treating nude mice bearing intracranial glioblastoma xenografts.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; Brain Neoplasms; Drug Delivery Systems; Glioblastoma; Humans; Liposomes; Magnetic Resonance Imaging; Male; Mice, Nude; Microbubbles; Paclitaxel; Ultrasonography; Xenograft Model Antitumor Assays | 2017 |
Glioma and microenvironment dual targeted nanocarrier for improved antiglioblastoma efficacy.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel | 2017 |
Self-Assembled Tumor-Penetrating Peptide-Modified Poly(l-γ-glutamylglutamine)-Paclitaxel Nanoparticles Based on Hydrophobic Interaction for the Treatment of Glioblastoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Humans; Hydrophobic and Hydrophilic Interactions; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Peptides; Proteins; Rats | 2017 |
Co-targeting the tumor endothelium and P-selectin-expressing glioblastoma cells leads to a remarkable therapeutic outcome.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Carriers; Drug Synergism; Drug Therapy; Glioblastoma; Glycerol; Humans; Mice; P-Selectin; Paclitaxel; Polymers; Protein Binding; Thrombospondin 1; Treatment Outcome | 2017 |
Enhanced blood brain barrier permeability and glioblastoma cell targeting via thermoresponsive lipid nanoparticles.
Topics: Blood-Brain Barrier; Cell Line, Tumor; Drug Delivery Systems; Drug Liberation; Glioblastoma; Humans; Lipids; Nanoparticles; Paclitaxel; Particle Size; Permeability; Temperature | 2017 |
BQ123 selectively improved tumor perfusion and enhanced nanomedicine delivery for glioblastomas treatment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Delivery Systems; Endothelin Receptor Antagonists; Glioblastoma; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Peptides, Cyclic | 2018 |
Nanomedicines in the treatment of brain tumors.
Topics: Brain Neoplasms; Doxorubicin; Drug Delivery Systems; Glioblastoma; Humans; Nanomedicine; Nanoparticles; Paclitaxel; Theranostic Nanomedicine | 2018 |
Mechanisms of enhanced antiglioma efficacy of polysorbate 80-modified paclitaxel-loaded PLGA nanoparticles by focused ultrasound.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apolipoproteins E; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain Neoplasms; Disease Models, Animal; Drug Compounding; Drug Delivery Systems; Drug Liberation; Extracorporeal Shockwave Therapy; Female; Gene Expression; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Polysorbates; Survival Analysis; Tight Junctions | 2018 |
Post-resection treatment of glioblastoma with an injectable nanomedicine-loaded photopolymerizable hydrogel induces long-term survival.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Drug Liberation; Female; Glioblastoma; Humans; Hydrogels; Intraoperative Period; Lactic Acid; Methacrylates; Mice; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2018 |
Targeting chemo-proton therapy on C6 cell line using superparamagnetic iron oxide nanoparticles conjugated with folate and paclitaxel.
Topics: Animals; Biological Transport; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Folic Acid; Glioblastoma; Intracellular Space; Magnetite Nanoparticles; Paclitaxel; Proton Therapy; Radiation-Sensitizing Agents; Rats | 2018 |
Magnetic targeting of paclitaxel-loaded poly(lactic-
Topics: Animals; Blood-Brain Barrier; Cell Line, Tumor; Endocytosis; Female; Glioblastoma; Humans; Lactic Acid; Magnetics; Mice, Nude; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Survival Analysis; Tissue Distribution; Xenograft Model Antitumor Assays | 2018 |
Peptide-functionalized and high drug loaded novel nanoparticles as dual-targeting drug delivery system for modulated and controlled release of paclitaxel to brain glioma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; Brain Neoplasms; Cattle; Cell Line, Tumor; Cells, Cultured; Delayed-Action Preparations; Drug Delivery Systems; Endothelial Cells; Glioblastoma; Glioma; Humans; Nanoparticles; Paclitaxel; Peptides; Polymers; Rats; Rats, Sprague-Dawley; Receptors, LDL; Tissue Distribution | 2018 |
Drug combination using an injectable nanomedicine hydrogel for glioblastoma treatment.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Deoxycytidine; Drug Carriers; Drug Combinations; Drug Liberation; Gemcitabine; Glioblastoma; Hydrogels; Injections; Lipids; Mice; Nanocapsules; Nanomedicine; Paclitaxel; Rats | 2019 |
High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Docetaxel; Drug Delivery Systems; Female; Flow Cytometry; Glioblastoma; Humans; Immunohistochemistry; Immunotherapy; Lipoproteins, HDL; Lomustine; Mice; Models, Biological; Paclitaxel; Rats; T-Lymphocytes | 2019 |
Resveratrol Enhances Apoptotic and Oxidant Effects of Paclitaxel through TRPM2 Channel Activation in DBTRG Glioblastoma Cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Apoptosis; Glioblastoma; Humans; Oxidants; Paclitaxel; Reactive Oxygen Species; Resveratrol; TRPM Cation Channels | 2019 |
Fine-Tuning the Linear Release Rate of Paclitaxel-Bearing Supramolecular Filament Hydrogels through Molecular Engineering.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Liberation; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Hydrogels; Hydrophobic and Hydrophilic Interactions; Macromolecular Substances; Nanostructures; Paclitaxel; Particle Size; Prodrugs; Structure-Activity Relationship; Surface Properties | 2019 |
Peptide-guided nanoparticles for glioblastoma targeting.
Topics: Albumins; Animals; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Endothelial Cells; Female; Ferric Compounds; Glioblastoma; Humans; Male; Metal Nanoparticles; Mice; Mice, Inbred C57BL; Mice, Nude; Nanoparticles; Paclitaxel; Peptides; Silver; Xenograft Model Antitumor Assays | 2019 |
Codelivery of paclitaxel and temozolomide through a photopolymerizable hydrogel prevents glioblastoma recurrence after surgical resection.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Combinations; Drug Delivery Systems; Female; Glioblastoma; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Mice, Nude; Neoplasm Recurrence, Local; Paclitaxel; Temozolomide | 2019 |
Paclitaxel incorporated exosomes derived from glioblastoma cells: comparative study of two loading techniques.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Exosomes; Glioblastoma; Humans; Paclitaxel; Particle Size | 2019 |
Targeted and effective glioblastoma therapy via aptamer-modified tetrahedral framework nucleic acid-paclitaxel nanoconjugates that can pass the blood brain barrier.
Topics: Animals; Aptamers, Nucleotide; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Nanoconjugates; Paclitaxel; Rats | 2019 |
Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs.
Topics: 2-Aminopurine; Animals; Antimitotic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle Proteins; Cell Survival; Drug Resistance, Neoplasm; France; Frozen Sections; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; M Phase Cell Cycle Checkpoints; Mice; Mice, Nude; Netherlands; ortho-Aminobenzoates; Paclitaxel; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; RNA Interference; United States; Up-Regulation; Vincristine; Xenograft Model Antitumor Assays | 2013 |
Biliverdin reductase plays a crucial role in hypoxia-induced chemoresistance in human glioblastoma.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Humans; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Paclitaxel; Reactive Oxygen Species; Temozolomide | 2013 |
Comparison of the effects of photon versus carbon ion irradiation when combined with chemotherapy in vitro.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carbon; Cell Cycle; Cell Line, Tumor; Cell Separation; Chemoradiotherapy; Cisplatin; Colonic Neoplasms; Deoxycytidine; Dose-Response Relationship, Radiation; Drug Screening Assays, Antitumor; Flow Cytometry; Gemcitabine; Glioblastoma; Humans; Ions; Lung Neoplasms; Paclitaxel; Pancreatic Neoplasms; Photons; Propidium; Radiotherapy; Relative Biological Effectiveness; Time Factors | 2013 |
Development of high drug loaded and customizing novel nanoparticles for modulated and controlled release of Paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Delayed-Action Preparations; Emulsions; Glioblastoma; Humans; Materials Testing; Nanoparticles; Paclitaxel; Thermodynamics | 2014 |
Prion-like nanofibrils of small molecules (PriSM) selectively inhibit cancer cells by impeding cytoskeleton dynamics.
Topics: Antineoplastic Agents; Apoptosis; Cytoskeleton; Endocytosis; Glioblastoma; HeLa Cells; Hep G2 Cells; Humans; MCF-7 Cells; Nanoparticles; Nanotechnology; Neoplasm Transplantation; Neoplasms; Nocodazole; Paclitaxel; Peptides; Prions; Protein Structure, Tertiary; tau Proteins; Tubulin | 2014 |
Polyethylene glycol-polylactic acid nanoparticles modified with cysteine-arginine-glutamic acid-lysine-alanine fibrin-homing peptide for glioblastoma therapy by enhanced retention effect.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Fibrin; Glioblastoma; Humans; Lactates; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Oligopeptides; Paclitaxel; Polyethylene Glycols; Random Allocation; Survival Analysis; Xenograft Model Antitumor Assays | 2014 |
Positive-charged solid lipid nanoparticles as paclitaxel drug delivery system in glioblastoma treatment.
Topics: Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Stability; Glioblastoma; Humans; Lipids; Nanoparticles; Paclitaxel; Particle Size; Surface Properties | 2014 |
Human CD14+ cells loaded with Paclitaxel inhibit in vitro cell proliferation of glioblastoma.
Topics: Antineoplastic Agents; Cancer Vaccines; Cell Differentiation; Cell Line; Cell Proliferation; Cell- and Tissue-Based Therapy; Culture Media, Conditioned; Dendritic Cells; Drug Delivery Systems; Glioblastoma; Humans; Lipopolysaccharide Receptors; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Paclitaxel | 2015 |
Tailored polymer-lipid hybrid nanoparticles for the delivery of drug conjugate: dual strategy for brain targeting.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Lipids; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Polymers; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2015 |
The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Glioblastoma; Humans; Paclitaxel; Temozolomide | 2015 |
SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Dacarbazine; Doxorubicin; Genotype; Glioblastoma; Humans; Kaplan-Meier Estimate; Paclitaxel; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Proteins; Temozolomide; Valproic Acid | 2015 |
Drug-Induced Self-Assembly of Modified Albumins as Nano-theranostics for Tumor-Targeted Combination Therapy.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chlorophyllides; Combined Modality Therapy; Female; Glioblastoma; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Models, Molecular; Molecular Targeted Therapy; Oligopeptides; Paclitaxel; Porphyrins; Protein Aggregates; Protein Conformation; Serum Albumin; Theranostic Nanomedicine | 2015 |
Enhancing Glioblastoma-Specific Penetration by Functionalization of Nanoparticles with an Iron-Mimic Peptide Targeting Transferrin/Transferrin Receptor Complex.
Topics: Animals; Antigens, CD; Apoptosis; Blood-Brain Barrier; Brain; Cell Proliferation; Cells, Cultured; Drug Delivery Systems; Glioblastoma; Iron; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Peptide Fragments; Photoelectron Spectroscopy; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Transferrin; Tissue Distribution; Transferrin | 2015 |
Mammary-Derived Growth Inhibitor Targeting Peptide-Modified PEG-PLA Nanoparticles for Enhanced Targeted Glioblastoma Therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Drug Delivery Systems; Fatty Acid Binding Protein 3; Fatty Acid-Binding Proteins; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Peptide Fragments; Polyethylene Glycols | 2015 |
Characterization of Dynamic Behaviour of MCF7 and MCF10A Cells in Ultrasonic Field Using Modal and Harmonic Analyses.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Astrocytes; Brain Neoplasms; Breast; Breast Neoplasms; Cell Line; Cell Line, Tumor; Computer Simulation; Elasticity; Female; Glioblastoma; Humans; MCF-7 Cells; Models, Biological; Paclitaxel; Ultrasonic Therapy; Ultrasonic Waves | 2015 |
Development of multifunctional lipid nanocapsules for the co-delivery of paclitaxel and CpG-ODN in the treatment of glioblastoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Chitosan; Drug Screening Assays, Antitumor; Drug Stability; Female; Glioblastoma; Lipids; Magnetic Resonance Imaging; Mice; Nanocapsules; Oligodeoxyribonucleotides; Paclitaxel | 2015 |
Mesenchymal stromal cells loaded with paclitaxel induce cytotoxic damage in glioblastoma brain xenografts.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Paclitaxel; Rats; Rats, Wistar | 2015 |
Improved anti-glioblastoma efficacy by IL-13Rα2 mediated copolymer nanoparticles loaded with paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Glioblastoma; Interleukin-13 Receptor alpha2 Subunit; Male; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Nanoparticles; Paclitaxel; Rats; Tissue Distribution; Xenograft Model Antitumor Assays | 2015 |
Polymer Nanocomposites Based Thermo-Sensitive Gel for Paclitaxel and Temozolomide Co-Delivery to Glioblastoma Cells.
Topics: Animals; Cell Line, Tumor; Dacarbazine; Drug Carriers; Glioblastoma; Humans; Nanocomposites; Paclitaxel; Polyesters; Polyethylene Glycols; Rats; Temozolomide | 2015 |
The synergic antitumor effects of paclitaxel and temozolomide co-loaded in mPEG-PLGA nanoparticles on glioblastoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Dacarbazine; Drug Carriers; Drug Delivery Systems; Drug Synergism; Female; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Polyesters; Polyethylene Glycols; Rats; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Synergistic targeting tenascin C and neuropilin-1 for specific penetration of nanoparticles for anti-glioblastoma treatment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice, Inbred BALB C; Nanoparticles; Neuropilin-1; Paclitaxel; Peptides; Tenascin | 2016 |
Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery t
Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemotaxis; Cyclic GMP-Dependent Protein Kinase Type I; Dacarbazine; Doxorubicin; Female; Glioblastoma; Glioma; Humans; Male; Mice; Mice, Transgenic; Neoplasm Invasiveness; Neoplastic Stem Cells; Neurons; Oligonucleotide Array Sequence Analysis; Paclitaxel; Phenotype; Stem Cells; Temozolomide | 2016 |
Precise glioblastoma targeting by AS1411 aptamer-functionalized poly (l-γ-glutamylglutamine)-paclitaxel nanoconjugates.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aptamers, Nucleotide; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Mice, Inbred BALB C; Mice, Nude; Nanoconjugates; Oligodeoxyribonucleotides; Paclitaxel; Proteins | 2017 |
Mesoporous carbon nanoshells for high hydrophobic drug loading, multimodal optical imaging, controlled drug release, and synergistic therapy.
Topics: Animals; Carbon; Drug Carriers; Drug Liberation; Glioblastoma; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Nude; Nanoshells; Paclitaxel; Rats; Xenograft Model Antitumor Assays | 2017 |
Human mesenchymal stromal cells inhibit tumor growth in orthotopic glioblastoma xenografts.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Glioblastoma; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Paclitaxel; Rats; Xenograft Model Antitumor Assays | 2017 |
Ran suppresses paclitaxel-induced apoptosis in human glioblastoma cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Cell Line, Tumor; Enzyme Activation; G1 Phase; Gene Library; Glioblastoma; Humans; JNK Mitogen-Activated Protein Kinases; Models, Biological; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; ran GTP-Binding Protein; Reactive Oxygen Species; Saccharomyces cerevisiae | 2008 |
Differential sensitivity of human glioblastoma LN18 (PTEN-positive) and A172 (PTEN-negative) cells to Taxol for apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Line, Tumor; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Glioblastoma; Humans; Mitochondria; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; PTEN Phosphohydrolase; Signal Transduction; Vascular Endothelial Growth Factor A | 2008 |
N-(4-Hydroxyphenyl) retinamide potentiated paclitaxel for cell cycle arrest and apoptosis in glioblastoma C6 and RG2 cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Astrocytes; Cadherins; Calpain; Cathepsins; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Survival; Fenretinide; Gene Expression; Glioblastoma; Inhibitor of Differentiation Protein 2; Paclitaxel; Proliferating Cell Nuclear Antigen; Rats; Telomerase; Tumor Suppressor Proteins | 2009 |
Paclitaxel delivery from PLGA foams for controlled release in post-surgical chemotherapy against glioblastoma multiforme.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Division; Cell Line, Tumor; Chemotherapy, Adjuvant; Delayed-Action Preparations; Drug Evaluation, Preclinical; Drug Implants; Glioblastoma; Lactic Acid; Mice; Mice, Inbred BALB C; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rats; Rats, Wistar; Tissue Distribution | 2009 |
Combination of taxol and Bcl-2 siRNA induces apoptosis in human glioblastoma cells and inhibits invasion, angiogenesis and tumour growth.
Topics: Animals; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Down-Regulation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; In Situ Nick-End Labeling; Mice; Neoplasm Invasiveness; Neovascularization, Pathologic; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; RNA, Small Interfering; Subcutaneous Tissue; Xenograft Model Antitumor Assays | 2009 |
In vivo evaluation of intracellular drug-nanocarriers infused into intracranial tumours by convection-enhanced delivery: distribution and radiosensitisation efficacy.
Topics: Animals; Brain Neoplasms; Cell Separation; Combined Modality Therapy; Convection; Female; Flow Cytometry; Glioblastoma; Microscopy, Confocal; Nanocapsules; Nanotechnology; Paclitaxel; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344 | 2010 |
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and paclitaxel have cooperative in vivo effects against glioblastoma multiforme cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Brain Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Synergism; Fluorodeoxyglucose F18; Glioblastoma; Humans; Luminescent Measurements; Mice; Mice, Nude; Paclitaxel; Positron-Emission Tomography; TNF-Related Apoptosis-Inducing Ligand; Treatment Outcome; Tumor Burden; Tumor Suppressor Protein p53; X-Ray Microtomography; Xenograft Model Antitumor Assays | 2009 |
Cyclic RGD conjugated poly(ethylene glycol)-co-poly(lactic acid) micelle enhances paclitaxel anti-glioblastoma effect.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Glioblastoma; Humans; Inhibitory Concentration 50; Injections, Intravenous; Integrin alphaVbeta3; Lactates; Mice; Mice, Nude; Micelles; Paclitaxel; Particle Size; Peptides, Cyclic; Polyethylene Glycols; Technology, Pharmaceutical; Tumor Burden; Xenograft Model Antitumor Assays | 2010 |
MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Inhibitory Concentration 50; MicroRNAs; Models, Biological; Paclitaxel; Phosphorylation; PTEN Phosphohydrolase; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles | 2010 |
Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Diphosphonates; Drug Synergism; Flow Cytometry; Geranyltranstransferase; Glioblastoma; Humans; JNK Mitogen-Activated Protein Kinases; Mevalonic Acid; Paclitaxel; Pamidronate; Polyisoprenyl Phosphates; Sesquiterpenes; Signal Transduction; Time Factors; Tumor Suppressor Protein p53 | 2010 |
The use of submicron/nanoscale PLGA implants to deliver paclitaxel with enhanced pharmacokinetics and therapeutic efficacy in intracranial glioblastoma in mice.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Implants; Glioblastoma; Male; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Nanostructures; Paclitaxel; Treatment Outcome | 2010 |
Enhanced anti-glioblastoma efficacy by PTX-loaded PEGylated poly(ɛ-caprolactone) nanoparticles: In vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Cell Survival; Drug Carriers; Drug Delivery Systems; Drug Stability; Drug Storage; Emulsions; Glioblastoma; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Time Factors | 2010 |
The role of paclitaxel in the development and treatment of multidrug resistant cancer cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Death; Cell Line, Tumor; Colonic Neoplasms; Disease Progression; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glioblastoma; Glutathione; Humans; Inactivation, Metabolic; Paclitaxel; Rhodamine 123; RNA, Messenger; Vascular Endothelial Growth Factor A | 2011 |
Valproic acid induced differentiation and potentiated efficacy of taxol and nanotaxol for controlling growth of human glioblastoma LN18 and T98G cells.
Topics: Albumin-Bound Paclitaxel; Albumins; Apoptosis; Apoptosis Inducing Factor; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase 3; Caspase 8; Caspase 9; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cytochromes c; Down-Regulation; Drug Therapy, Combination; Glioblastoma; Humans; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Valproic Acid | 2011 |
PEGylated poly(trimethylene carbonate) nanoparticles loaded with paclitaxel for the treatment of advanced glioma: in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Dioxanes; Drug Carriers; Female; Glioblastoma; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2011 |
Glucosylceramide synthase protects glioblastoma cells against autophagic and apoptotic death induced by temozolomide and Paclitaxel.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Central Nervous System Neoplasms; Ceramides; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Glucosyltransferases; Humans; Paclitaxel; Temozolomide | 2012 |
Anti-miR-155 oligonucleotide enhances chemosensitivity of U251 cell to taxol by inducing apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Down-Regulation; Ether-A-Go-Go Potassium Channels; Glioblastoma; Humans; MicroRNAs; Oligonucleotides, Antisense; Paclitaxel | 2012 |
In vitro evaluation of photon and carbon ion radiotherapy in combination with chemotherapy in glioblastoma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carbon; Cell Line, Tumor; Chemoradiotherapy; Cisplatin; Deoxycytidine; Dose-Response Relationship, Radiation; Gemcitabine; Glioblastoma; Humans; In Vitro Techniques; Paclitaxel; Photons; Tumor Stem Cell Assay | 2012 |
Proteasome inhibitor MG132 induces selective apoptosis in glioblastoma cells through inhibition of PI3K/Akt and NFkappaB pathways, mitochondrial dysfunction, and activation of p38-JNK1/2 signaling.
Topics: Adjuvants, Pharmaceutic; Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspase 3; Cell Cycle; Cell Line, Tumor; Cisplatin; Doxorubicin; Glioblastoma; Humans; Leupeptins; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; NF-kappa B; Paclitaxel; Phosphoinositide-3 Kinase Inhibitors; Proteasome Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction | 2012 |
Co-delivery of TRAIL gene enhances the anti-glioblastoma effect of paclitaxel in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Male; Mice; Mice, Inbred BALB C; Paclitaxel; Peptides; Peptides, Cyclic; Plasmids; Polyethylene Glycols; Polyethyleneimine; TNF-Related Apoptosis-Inducing Ligand; Transfection; Tumor Burden | 2012 |
Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cell Line, Tumor; Glioblastoma; Humans; Integrin alphaVbeta3; Paclitaxel; Peptides, Cyclic | 2012 |
The influence of the combined treatment with Vadimezan (ASA404) and taxol on the growth of U251 glioblastoma xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Line, Tumor; Female; Fluorodeoxyglucose F18; Glioblastoma; Humans; Mice; Mice, Nude; Paclitaxel; Positron-Emission Tomography; Tumor Burden; Xanthones; Xenograft Model Antitumor Assays | 2012 |
Anti-glioblastoma efficacy and safety of paclitaxel-loading Angiopep-conjugated dual targeting PEG-PCL nanoparticles.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Humans; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Nanoparticles; Paclitaxel; Peptides; Polyethylene Glycols | 2012 |
Synergistic anti-cancer mechanisms of curcumin and paclitaxel for growth inhibition of human brain tumor stem cells and LN18 and U138MG cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line; Curcumin; Drug Synergism; Glioblastoma; Humans; Microscopy, Fluorescence; Neoplastic Stem Cells; Paclitaxel | 2012 |
Proapoptotic miltefosine nanovesicles show synergism with paclitaxel: Implications for glioblastoma multiforme therapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Drug Synergism; Female; Glioblastoma; Humans; Male; Nanostructures; Paclitaxel; Phosphorylcholine; Rats; Rats, Wistar | 2013 |
PEG-co-PCL nanoparticles modified with MMP-2/9 activatable low molecular weight protamine for enhanced targeted glioblastoma therapy.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Coumarins; Diagnostic Imaging; Drug Delivery Systems; Endocytosis; Ethylene Oxide; Glioblastoma; Kaplan-Meier Estimate; Lactones; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Molecular Weight; Nanoparticles; Paclitaxel; Protamines; Rats; Rats, Sprague-Dawley; Spheroids, Cellular; Tissue Distribution | 2013 |
Enhancing the efficacy of drug-loaded nanocarriers against brain tumors by targeted radiation therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Drug Carriers; Drug Delivery Systems; Glioblastoma; Green Fluorescent Proteins; Humans; Luciferases; Mice; Mice, Nude; Micelles; Microscopy, Fluorescence; Nanostructures; Paclitaxel; Polymers; Treatment Outcome; Xenograft Model Antitumor Assays | 2013 |
The effect of functionalizing lipid nanocapsules with NFL-TBS.40-63 peptide on their uptake by glioblastoma cells.
Topics: Animals; Astrocytes; Brain; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Female; Glioblastoma; Lipids; Mice; Mice, Inbred C57BL; Nanocapsules; Neurofilament Proteins; Paclitaxel; Peptide Fragments; Protein Binding | 2013 |
Bcl-xL antisense oligonucleotides chemosensitize human glioblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; bcl-X Protein; Blotting, Western; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Humans; Oligonucleotides, Antisense; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2002 |
Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain Neoplasms; Capillaries; Cells, Cultured; Cyclosporins; Glioblastoma; Glioma; Humans; Paclitaxel; Swine; Tumor Cells, Cultured | 2002 |
Comparison of antiangiogenic activities using paclitaxel (taxol) and docetaxel (taxotere).
Topics: Angiogenesis Inhibitors; Animals; Aorta; Apoptosis; Capillaries; Carcinoma, Non-Small-Cell Lung; Cell Differentiation; Cell Division; Cells, Cultured; Chemotaxis; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Endothelium, Vascular; Fibrosarcoma; Glioblastoma; Humans; Lung Neoplasms; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Rats; Taxoids; Tumor Cells, Cultured; Umbilical Veins; Xenograft Model Antitumor Assays | 2003 |
Interobserver variability in the radiological assessment of response to chemotherapy in glioma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplatin; Dacarbazine; Ependymoma; Female; Glioblastoma; Glioma; Humans; Image Enhancement; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Observer Variation; Oligodendroglioma; Paclitaxel; Procarbazine; Sensitivity and Specificity; Temozolomide; Tomography, X-Ray Computed; Treatment Outcome; Vincristine | 2003 |
IDN 5390: an oral taxane candidate for protracted treatment schedules.
Topics: Administration, Oral; Animals; Brain Neoplasms; Bridged-Ring Compounds; Carcinoma; Colonic Neoplasms; Drug Administration Schedule; Female; Glioblastoma; Humans; Injections, Subcutaneous; Mice; Mice, Nude; Neoplasms, Experimental; Ovarian Neoplasms; Paclitaxel; Taxoids; Transplantation, Heterologous | 2003 |
Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Becaplermin; Benzimidazoles; Cell Growth Processes; Female; Glioblastoma; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neovascularization, Pathologic; Paclitaxel; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Quinolines; Rats; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Xenograft Model Antitumor Assays | 2005 |
Local chemotherapy of F98 rat glioblastoma with paclitaxel and carboplatin embedded in liquid crystalline cubic phases.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Brain; Brain Neoplasms; Carboplatin; Crystallization; Diffusion; Drug Carriers; Drug Compounding; Drug Delivery Systems; Glioblastoma; Male; Neoplasm Transplantation; Paclitaxel; Rats; Rats, Inbred F344; Survival | 2005 |
Intracavitary chemotherapy (paclitaxel/carboplatin liquid crystalline cubic phases) for recurrent glioblastoma -- clinical observations.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Edema; Brain Neoplasms; Carboplatin; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Carriers; Drug Delivery Systems; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Pilot Projects; Survival Analysis | 2005 |
Synergistic effect and condition of pegylated interferon alpha with paclitaxel on glioblastoma.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Synergism; Glioblastoma; Glioma; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Interferon-alpha; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Polyethylene Glycols; Transplantation, Heterologous | 2006 |
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Fluoresceins; Glioblastoma; Humans; Insecticides; Kinesins; Molecular Structure; Paclitaxel; Pyrimidines; Quinazolines; Rotenone; Spindle Apparatus; Tetrahydroisoquinolines; Thiones; Time Factors; Tubulin; Tubulin Modulators; Vinblastine | 2007 |
Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells.
Topics: Adenosine; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-Associated Death Protein; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Glioblastoma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptor, Adenosine A3 | 2007 |
Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells.
Topics: Adult; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Child; Glioblastoma; Humans; Multiprotein Complexes; Nocodazole; Paclitaxel; Tubulin; Tubulin Modulators; Vinblastine | 2007 |
Differentiation decreased telomerase activity in rat glioblastoma C6 cells and increased sensitivity to IFN-gamma and taxol for apoptosis.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Calcium; Caspase 8; Cell Differentiation; Cell Line, Tumor; DNA Fragmentation; Electrophoretic Mobility Shift Assay; Enzyme Activation; Glioblastoma; Interferon-gamma; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Rats; Recombinant Proteins; Retinoids; Telomerase | 2007 |
Combination of all-trans retinoic acid and taxol regressed glioblastoma T98G xenografts in nude mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Female; Glioblastoma; Graft Survival; Humans; Mice; Mice, Nude; Paclitaxel; Transplantation, Heterologous; Tretinoin | 2007 |
Synthetic nano-LDL with paclitaxel oleate as a targeted drug delivery vehicle for glioblastoma multiforme.
Topics: Amino Acids; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Emulsions; Feasibility Studies; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Glioblastoma; Humans; Inhibitory Concentration 50; Lipoproteins, LDL; Microscopy, Fluorescence; Nanoparticles; Oleic Acid; Paclitaxel; Particle Size; Peptides; Pharmaceutical Vehicles; Protein Structure, Tertiary; Receptors, LDL | 2007 |
Retinoids induced astrocytic differentiation with down regulation of telomerase activity and enhanced sensitivity to taxol for apoptosis in human glioblastoma T98G and U87MG cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Astrocytes; Blotting, Western; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Down-Regulation; Glioblastoma; Humans; Isotretinoin; Paclitaxel; Reactive Oxygen Species; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Telomerase; Tretinoin | 2008 |
Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Differentiation; Cell Line, Tumor; Central Nervous System Neoplasms; Cysteine Endopeptidases; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Inhibitor of Apoptosis Proteins; Mice; Mice, Nude; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Paclitaxel; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Telomerase; Tretinoin; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays | 2008 |
Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3.
Topics: Animals; Antibodies; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Autophagy; Cell Line, Tumor; Ceramides; Dacarbazine; Female; Glioblastoma; Humans; Mice; Mice, Nude; Microtubule-Associated Proteins; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Oxides; Paclitaxel; Phagosomes; Survival Rate; Temozolomide; Transplantation, Heterologous; Tubulin Modulators | 2008 |
Bcl-2 siRNA augments taxol mediated apoptotic death in human glioblastoma U138MG and U251MG cells.
Topics: Apoptosis; BH3 Interacting Domain Death Agonist Protein; Calcium; Calpain; Caspase 3; Cell Line, Tumor; Cytochromes c; Dose-Response Relationship, Drug; Down-Regulation; Fluorescent Antibody Technique; Glioblastoma; Humans; In Situ Nick-End Labeling; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering | 2009 |
In vitro assessment of Taxol for human glioblastoma: chemosensitivity and cellular locomotion.
Topics: Cell Movement; Glioblastoma; Humans; Paclitaxel; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1995 |
A saturation threshold for taxol cytotoxicity in human glial and neuroblastoma cells.
Topics: Brain Neoplasms; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Kinetics; Neuroblastoma; Neuroectodermal Tumors, Primitive; Paclitaxel; Tumor Cells, Cultured | 1993 |
Thromboembolic events with paclitaxel.
Topics: Aged; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Humans; Male; Paclitaxel; Radiation-Sensitizing Agents; Thromboembolism | 1996 |
The development of a novel intraperitoneal tumor-seeding prophylactic.
Topics: Animals; Antineoplastic Agents, Phytogenic; Dose-Response Relationship, Drug; Glioblastoma; Injections, Intraperitoneal; Microspheres; Neoplasm Seeding; Neoplasm Transplantation; Paclitaxel; Peritoneal Neoplasms; Rats; Rats, Wistar | 1997 |
Proliferation, migration and invasion of human glioma cells exposed to paclitaxel (Taxol) in vitro.
Topics: Adult; Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Division; Cell Movement; Female; Flow Cytometry; Glioblastoma; Glioma; Glycerol; Humans; Microscopy, Confocal; Paclitaxel; Rats; Rats, Wistar; Solvents; Spheroids, Cellular; Tumor Cells, Cultured | 1997 |
Fractionated stereotactic radiosurgery and concurrent taxol in recurrent glioblastoma multiforme: a preliminary report.
Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Radiation-Sensitizing Agents; Radiosurgery | 1998 |
Recurrent glioblastoma multiforme: potential benefits using fractionated stereotactic radiotherapy and concurrent taxol.
Topics: Actuarial Analysis; Adult; Aged; Brain; Brain Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Female; Follow-Up Studies; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Paclitaxel; Pilot Projects; Radiation-Sensitizing Agents; Radiosurgery; Recurrence; Retrospective Studies; Survival Analysis; Treatment Outcome | 1997 |
Interaction of paclitaxel (Taxol) and irradiation. In-vitro differences between tumor and fibroblastic cells.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fibroblasts; Flow Cytometry; Glioblastoma; Humans; Lung Neoplasms; Paclitaxel; Particle Accelerators; Radiation-Sensitizing Agents; Radiotherapy, High-Energy; Rodentia; Time Factors; Tumor Cells, Cultured | 1999 |
Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blood Vessels; Brain Neoplasms; Docetaxel; Female; Glioblastoma; Humans; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Paclitaxel; Pressure; Sarcoma, Experimental; Specific Pathogen-Free Organisms; Taxoids; Tumor Cells, Cultured | 1999 |
Paclitaxel loaded poly(L-lactic acid) microspheres for the prevention of intraperitoneal carcinomatosis after a surgical repair and tumor cell spill.
Topics: Animals; Carbon Dioxide; Cecum; Drug Delivery Systems; Glioblastoma; Insufflation; Intraoperative Complications; Lactic Acid; Male; Microspheres; Paclitaxel; Peritoneal Cavity; Polyesters; Polymers; Rats; Rats, Wistar | 2000 |
[Roles of p53 in chemotherapy of glioblastoma].
Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cisplatin; Etoposide; Flow Cytometry; Glioblastoma; Nimustine; Paclitaxel; Polymerase Chain Reaction; Temperature; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Efficacy of BCNU and paclitaxel loaded subcutaneous implants in the interstitial chemotherapy of U-87 MG human glioblastoma xenografts.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Drug Implants; Excipients; Glioblastoma; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Polymers | 2002 |