paclitaxel has been researched along with Animal Mammary Carcinoma in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (16.28) | 18.2507 |
| 2000's | 9 (20.93) | 29.6817 |
| 2010's | 24 (55.81) | 24.3611 |
| 2020's | 3 (6.98) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, AL; Chaplin, DJ; Charlton-Sevcik, AK; Chavarria, GE; Horsman, MR; Kishore Kumar, GD; Odutola, SO; Parker, EN; Pinney, KG; Siemann, DW; Song, J; Strecker, TE; Sudhan, DR; Trawick, ML; Wittenborn, TR | 1 |
| Akrami, M; Davaran, S; Farboudi, A; Irani, M; Nouri, A; Shirinzad, S; Sojoudi, P | 1 |
| Chourasia, MK; Dixit, S; Konwar, R; Meher, JG; Pawar, VK; Saklani, R; Singh, Y | 1 |
| Drahošová, S; Hodorová, I; Kreheľová, A; Mihalik, J; Pastornická, A; Pavliuk-Karachevtseva, A; Rybárová, S | 1 |
| Adachi, Y; Hattori, M; Iwata, H; Kikumori, T; Kodera, Y; Kondo, N; Nakanishi, H; Nishida, K; Shibata, K; Usuki, H; Yatabe, Y; Yoshimura, M | 1 |
| Orhan, C; Ozercan, IH; Sahin, K; Sahin, N; Tuzcu, M; Yabas, M | 1 |
| Hu, Y; Nie, G; Song, Y; Tang, H; Wang, J; Wang, Y; Zhao, R; Zhu, X | 1 |
| Chang, H; Liu, Y; Ren, X; Wu, Y; Xiao, M; Zhao, B | 1 |
| David, A; Feinshtein, V; Rütter, M; Shpirt, L; Ventura, Y; Zaiden, M | 1 |
| Jin, Z; Lei, J; Li, Y; Liu, J; Meng, M; Sun, T; Wang, Q; Xu, H; Xue, H | 1 |
| Luna, JA; Mengatto, LN; Pesoa, JI; Rico, MJ; Rozados, VR; Scharovsky, OG | 1 |
| Chow, A; Kerbel, RS; Khan, KA; Krüger, J; Man, S; Paez-Ribes, M; Pham, E; Wu, FTH; Xu, P | 1 |
| Bush, B; Cam, M; DelRio, FW; Medina, SH; Nandy, K; Schneider, JP; Sevcik, E | 1 |
| Badr El-Din, NK; Ghoneum, M; Hassan, TA; Mahmoud, AZ; Pan, D; Tolentino, L | 1 |
| Fecková, B; Ilkovičová, L; Kimáková, P; Solár, P; Zsóková, E | 1 |
| Barber, CL; Daenen, LG; He, H; Hofmann, JJ; Iruela-Arispe, ML; Lane, TF; Monvoisin, A; Radtke, F; Roodhart, JM; van Amersfoort, M; Voest, EE | 1 |
| Barranger, E; Bertheau, P; Bousquet, G; de Bazelaire, C; Ferreira, I; Feugeas, JP; Janin, A; Jourdan, N; Vercellino, L | 1 |
| Akcakanat, A; Blanco, E; Cara, FE; Do, KA; Evans, KW; Ferrari, M; Gonzalez-Delgado, CA; Granados-Principal, S; Hsiao, A; Meric-Bernstam, F; Ruiz-Esparza, GU; Sangai, T; Wang, Y; Wu, S | 1 |
| Baabur-Cohen, H; Markovsky, E; Satchi-Fainaro, R | 1 |
| Hong, JT; Im, SA; Kim, K; Lee, CK; Lee, YH; Lee, YR; Park, CS; Song, S; Whang, BY | 1 |
| Chen, M; Chen, X; Dai, W; He, B; Lin, Z; Mei, D; Wang, X; Wang, Y; Wang, Z; Yin, Y; Zhang, H; Zhang, Q | 1 |
| Dong, W; Fu, Z; Han, R; Liu, H; Liu, Y; Meng, L; Wang, R; Xia, X; Ye, J | 1 |
| Balusikova, K; Bartunek, P; Kahle, M; Kolar, M; Kralova, J; Lettlova, S; Truksa, J | 1 |
| Ma, L; Panyam, J; Patil, Y; Sadhukha, T | 1 |
| Ma, G; Song, C; Yang, J; Zhang, L | 1 |
| Chakravarthi, SS; Robinson, DH | 1 |
| Brown, RJ; Gabrielson, E; Huso, DL; Jacobs, LK; Jeter, S; Khouri, NF; Kominsky, SL; Lange, JR; Mori, T; Powers, P; Rudek, MA; Stearns, V; Sukumar, S; Tarpinian, K; Tsangaris, TN; Yoshida, T; Zhang, Z | 1 |
| Bell-McGuinn, KM; Brogi, E; Elie, BT; Garfall, AL; Joyce, JA; Kester, JC; Olson, OC; Shree, T; Simpson, K; Zabor, EC | 1 |
| Torchilin, VP | 1 |
| Kamiyama, Y; Okugawa, H; Sakaida, N; Tanaka, K; Tanano, A; Uemura, Y; Yamamoto, D | 1 |
| Gulati, A; Rai, A; Rajeshkumar, NV | 2 |
| Chopra, A; Cohen, EP; Kim, TS; Martinez, D; O-Sullivan, I | 1 |
| Armstrong, L; Nielsen, LL; Porter, GM | 1 |
| DeNardo, DG; DeNardo, GL; DeNardo, SJ; Kroger, LA; Kukis, DL; Lamborn, KR; Meares, CF; Miers, LA; O'Donnell, RT | 1 |
| Arcangeli, G; Cividalli, A; Cordelli, E; Cruciani, G; Danesi, DT; Livdi, E | 1 |
| Dell, J; Gurnani, M; Hajian, G; Lipari, P; Nielsen, LL | 1 |
| Deisseroth, AB; Hanania, EG | 1 |
| Charnsangavej, C; Hunter, NR; Ke, S; Li, C; Milas, L; Price, JE; Wallace, S; Yu, DF | 1 |
| Cividalli, A; Cruciani, G; Livdi, E; Pasqualetti, P; Tirindelli Danesi, D | 1 |
| Carroll, J; Gurnani, M; Hajian, G; Johnson, RC; Mathis, JM; Nielsen, LL; Shi, B; Terracina, G | 1 |
| Vogel, SN; Zaks, TZ; Zaks-Zilberman, M | 1 |
| Ara, KY; Arai, K; Maruo, K; Matsuda, H; Uehara, K | 1 |
1 review(s) available for paclitaxel and Animal Mammary Carcinoma
| Article | Year |
|---|---|
Fluorescence microscopy to follow the targeting of liposomes and micelles to cells and their intracellular fate.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Drug Carriers; Drug Delivery Systems; Liposomes; Mammary Neoplasms, Animal; Mice; Micelles; Microscopy, Fluorescence; Paclitaxel; Technology, Pharmaceutical | 2005 |
1 trial(s) available for paclitaxel and Animal Mammary Carcinoma
| Article | Year |
|---|---|
Preclinical and clinical evaluation of intraductally administered agents in early breast cancer.
Topics: Adult; Animals; Antineoplastic Agents; Breast Neoplasms; Carboplatin; Doxorubicin; Drug Administration Routes; Female; Fluorouracil; Humans; Mammary Glands, Animal; Mammary Neoplasms, Animal; Methylnitrosourea; Paclitaxel; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Young Adult | 2011 |
41 other study(ies) available for paclitaxel and Animal Mammary Carcinoma
| Article | Year |
|---|---|
Synthesis and biochemical evaluation of benzoylbenzophenone thiosemicarbazone analogues as potent and selective inhibitors of cathepsin L.
Topics: Animals; Antineoplastic Agents; Benzophenones; Binding Sites; Cathepsin B; Cathepsin L; Cell Line, Tumor; Cell Movement; Cell Survival; Cysteine Proteinase Inhibitors; Drug Design; Female; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Isomerism; Kinetics; Mammary Neoplasms, Animal; Mice; Molecular Docking Simulation; Protein Structure, Tertiary; Thiosemicarbazones; Transplantation, Heterologous | 2015 |
Synthesis of magnetic gold coated poly (ε-caprolactonediol) based polyurethane/poly(N-isopropylacrylamide)-grafted-chitosan core-shell nanofibers for controlled release of paclitaxel and 5-FU.
Topics: Acrylic Resins; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chitosan; Coated Materials, Biocompatible; Delayed-Action Preparations; Drug Carriers; Female; Fluorouracil; Gold; Magnetic Iron Oxide Nanoparticles; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Nanofibers; Paclitaxel; Polyesters; Polyurethanes | 2020 |
Paclitaxel-Loaded Colloidal Silica and TPGS-Based Solid Self-Emulsifying System Interferes Akt/mTOR Pathway in MDA-MB-231 and Demonstrates Anti-tumor Effect in Syngeneic Mammary Tumors.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Cell Line, Tumor; Colloids; Drug Delivery Systems; Emulsions; Humans; Mammary Neoplasms, Animal; Paclitaxel; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Research Design; Silicon Dioxide; TOR Serine-Threonine Kinases; Vitamin E | 2020 |
Influence of Paclitaxel and Doxorubicin Therapy of ßIII-Tubulin, Carbonic Anhydrase IX, and Survivin in Chemically Induced Breast Cancer in Female Rat.
Topics: Animals; Carbonic Anhydrase IX; Doxorubicin; Female; Mammary Neoplasms, Animal; Paclitaxel; Rats, Sprague-Dawley; Survivin; Tubulin | 2021 |
Acute phase dynamics of circulating tumor cells after paclitaxel and doxorubicin chemotherapy in breast cancer mouse models.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Doxorubicin; Female; Humans; Mammary Neoplasms, Animal; Mice; Neoplastic Cells, Circulating; Paclitaxel; Prognosis | 2018 |
LFM-A13, a potent inhibitor of polo-like kinase, inhibits breast carcinogenesis by suppressing proliferation activity and inducing apoptosis in breast tumors of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amides; Animals; Apoptosis; Carcinogenesis; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Female; Humans; Mammary Neoplasms, Animal; Mice, Inbred BALB C; Nitriles; Paclitaxel; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Rats; Survival Analysis | 2018 |
Doxorubicin and paclitaxel carried by methoxy poly(ethylene glycol)-poly(lactide-co-glycolide) is superior than traditional drug-delivery methods.
Topics: Animals; Breast Neoplasms; Doxorubicin; Drug Delivery Systems; Female; Humans; Kidney; Mammary Neoplasms, Animal; Metabolomics; Mice; Nanoparticles; Paclitaxel; Polyesters; Polyethylene Glycols | 2018 |
Paclitaxel suppresses proliferation and induces apoptosis through regulation of ROS and the AKT/MAPK signaling pathway in canine mammary gland tumor cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dogs; Female; Mammary Neoplasms, Animal; Mitogen-Activated Protein Kinases; Paclitaxel; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2018 |
CD44-Targeted Polymer-Paclitaxel Conjugates to Control the Spread and Growth of Metastatic Tumors.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Delivery Systems; Female; Hyaluronan Receptors; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Paclitaxel; Polymers | 2018 |
A novel approach to monitoring the efficacy of anti-tumor treatments in animal models: combining functional MRI and texture analysis.
Topics: Allografts; Animals; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Contrast Media; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Animal; Mice; Paclitaxel; Treatment Outcome | 2018 |
Paclitaxel delivery system based on poly(lactide-co-glycolide) microparticles and chitosan thermo-sensitive gel for mammary adenocarcinoma treatment.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Female; Gels; Kinetics; Mammary Neoplasms, Animal; Mice, Inbred BALB C; Paclitaxel; Particle Size; Polyglactin 910; Temperature; Tumor Burden | 2018 |
Pre- and post-operative anti-PD-L1 plus anti-angiogenic therapies in mouse breast or renal cancer models of micro- or macro-metastatic disease.
Topics: Animals; B7-H1 Antigen; Bevacizumab; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Immunotherapy; Kidney Neoplasms; Mammary Neoplasms, Animal; Mice; Neoadjuvant Therapy; Neovascularization, Pathologic; Paclitaxel; Sunitinib | 2019 |
Identification of a mechanogenetic link between substrate stiffness and chemotherapeutic response in breast cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Doxorubicin; Extracellular Matrix; Female; Humans; Hydrogels; Male; Mammary Neoplasms, Animal; MCF-7 Cells; Methotrexate; Mice; Mice, Transgenic; Microscopy, Atomic Force; Paclitaxel; Surface Properties; Tamoxifen; Tumor Cells, Cultured; Tumor Microenvironment | 2019 |
Dietary baker's yeast sensitizes Ehrlich mammary adenocarcinoma to paclitaxel in mice bearing tumor.
Topics: Adenocarcinoma; Animals; Apoptosis; Carcinoma, Ehrlich Tumor; Cell Proliferation; Diet; DNA Damage; Female; Humans; Mammary Neoplasms, Animal; MCF-7 Cells; Mice; Paclitaxel; Saccharomyces cerevisiae; Tumor Burden | 2019 |
Erythropoietin receptor induces a paclitaxel resistance phenotype in mammary adenocarcinoma cells.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Drug Resistance, Neoplasm; Erythropoietin; Female; Humans; Mammary Neoplasms, Animal; Paclitaxel; Rats; Tumor Cells, Cultured | 2019 |
Notch1 regulates angio-supportive bone marrow-derived cells in mice: relevance to chemoresistance.
Topics: Animals; Antigens, CD; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bone Marrow Cells; Cadherins; Carcinoma, Lewis Lung; Cisplatin; Colorectal Neoplasms; Drug Resistance, Neoplasm; Mammary Neoplasms, Animal; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Paclitaxel; Receptor, Notch1; Xenograft Model Antitumor Assays | 2013 |
Individual xenograft as a personalized therapeutic resort for women with metastatic triple-negative breast carcinoma.
Topics: Adult; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Cisplatin; Cyclophosphamide; Docetaxel; Epirubicin; Female; Humans; Mammary Neoplasms, Animal; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Paclitaxel; Taxoids; Transplantation, Heterologous; Treatment Outcome; Triple Negative Breast Neoplasms | 2014 |
Colocalized delivery of rapamycin and paclitaxel to tumors enhances synergistic targeting of the PI3K/Akt/mTOR pathway.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mammary Neoplasms, Animal; MCF-7 Cells; Mice; Mice, Nude; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2014 |
Anticancer polymeric nanomedicine bearing synergistic drug combination is superior to a mixture of individually-conjugated drugs.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Combinations; Drug Synergism; Female; Humans; Mammary Neoplasms, Animal; Mice, Nude; Nanomedicine; Paclitaxel; Polyglutamic Acid; Polymers | 2014 |
Baccatin III, a precursor for the semisynthesis of paclitaxel, inhibits the accumulation and suppressive activity of myeloid-derived suppressor cells in tumor-bearing mice.
Topics: Alkaloids; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Female; Male; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Myeloid Cells; Paclitaxel; Reactive Oxygen Species; T-Lymphocytes; Taxoids | 2014 |
A comparative study of thermo-sensitive hydrogels with water-insoluble paclitaxel in molecule, nanocrystal and microcrystal dispersions.
Topics: Animals; Drug Screening Assays, Antitumor; Female; Hot Temperature; Hydrogels; Mammary Neoplasms, Animal; Mice; Nanoparticles; Paclitaxel; Solubility | 2015 |
Improved safety and efficacy of a lipid emulsion loaded with a paclitaxel-cholesterol complex for the treatment of breast tumors.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemistry, Pharmaceutical; Cholesterol; Drug Carriers; Drug Delivery Systems; Emulsions; Female; Humans; Lipids; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Particle Size; Triple Negative Breast Neoplasms | 2016 |
Glycol porphyrin derivatives and temoporfin elicit resistance to photodynamic therapy by different mechanisms.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Neoplasm; Ethylene Glycols; Female; Gene Knockdown Techniques; Glycols; Humans; Mammary Neoplasms, Animal; MCF-7 Cells; Mesoporphyrins; Mice; Paclitaxel; Photochemotherapy; Photosensitizing Agents; Porphyrins | 2017 |
Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotin; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Combinations; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; Leukemia, T-Cell; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quinolines | 2009 |
Effective antitumor activity of paclitaxel-loaded poly (epsilon-caprolactone)/pluronic F68 nanoparticles after intratumoral delivery into the murine breast cancer model.
Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Female; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Nanoparticles; Paclitaxel; Poloxamer; Polyesters | 2010 |
Enhanced cellular association of paclitaxel delivered in chitosan-PLGA particles.
Topics: Adhesiveness; Animals; Antineoplastic Agents, Phytogenic; Boron Compounds; Cell Line, Tumor; Chitosan; Drug Carriers; Female; Inhibitory Concentration 50; Lactic Acid; Mammary Neoplasms, Animal; Mice; Microscopy, Confocal; Microspheres; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2011 |
Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer.
Topics: Animals; Antineoplastic Agents; Cathepsins; Cell Line, Tumor; Doxorubicin; Drug Interactions; Drug Resistance, Neoplasm; Etoposide; Female; Lung Neoplasms; Macrophages; Mammary Neoplasms, Animal; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neoplasm Invasiveness; Paclitaxel | 2011 |
Effect of perductal paclitaxel exposure on the development of MNU-induced mammary carcinoma in female S-D rats.
Topics: Alkylating Agents; Animals; Antineoplastic Agents, Phytogenic; Female; Infusions, Parenteral; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Paclitaxel; Rats; Rats, Sprague-Dawley | 2005 |
Endothelin B receptor agonist, IRL 1620, enhances the anti-tumor efficacy of paclitaxel in breast tumor rats.
Topics: Alkylating Agents; Animals; Antineoplastic Agents, Phytogenic; Disease Progression; Endothelin B Receptor Antagonists; Endothelins; Female; Mammary Neoplasms, Animal; Methylnitrosourea; Paclitaxel; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Tissue Distribution | 2005 |
Combined therapy of an established, highly aggressive breast cancer in mice with paclitaxel and a unique DNA-based cell vaccine.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cancer Vaccines; Female; Mammary Neoplasms, Animal; Mice; Mice, Inbred C3H; Paclitaxel; Vaccines, DNA | 2006 |
Effect of the ET(B) receptor agonist, IRL-1620, on paclitaxel plasma pharmacokinetics of breast tumor rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Endothelins; Female; Mammary Neoplasms, Animal; Paclitaxel; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B | 2006 |
Strategy for developing transgenic assays for screening antineoplastic drugs that affect tubulin polymerization.
Topics: Animals; Drug Screening Assays, Antitumor; Immunohistochemistry; Male; Mammary Neoplasms, Animal; Mice; Mice, Nude; Mice, Transgenic; Microtubules; Neoplasms, Experimental; Paclitaxel; Salivary Gland Neoplasms; Tubulin | 1995 |
Synergy of Taxol and radioimmunotherapy with yttrium-90-labeled chimeric L6 antibody: efficacy and toxicity in breast cancer xenografts.
Topics: Animals; Antibodies; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Interleukin-6; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Paclitaxel; Radioimmunotherapy; Transplantation, Heterologous; Yttrium Radioisotopes | 1997 |
Enhancement of radiation response by paclitaxel in mice according to different treatment schedules.
Topics: Animals; Cell Division; DNA, Neoplasm; Drug Administration Schedule; Drug Screening Assays, Antitumor; Female; G2 Phase; Mammary Neoplasms, Animal; Mice; Paclitaxel; Radiation-Sensitizing Agents; Rats; Skin | 1998 |
Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer.
Topics: Adenoviridae; Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Combined Modality Therapy; Disease Models, Animal; Drug Synergism; Female; Gene Transfer Techniques; Genes, p53; Genetic Therapy; Genetic Vectors; Head and Neck Neoplasms; Humans; Male; Mammary Neoplasms, Animal; Mice; Microtubules; Neoplasms; Ovarian Neoplasms; Paclitaxel; Prostatic Neoplasms; Transduction, Genetic; Treatment Outcome; Tumor Cells, Cultured | 1998 |
Simultaneous genetic chemoprotection of normal marrow cells and genetic chemosensitization of breast cancer cells in a mouse cancer gene therapy model.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Chemoprevention; Disease Models, Animal; DNA, Complementary; Drug Resistance, Neoplasm; Female; Genetic Therapy; Humans; Mammary Neoplasms, Animal; Metallothionein; Mice; Mice, Inbred BALB C; Paclitaxel; Promoter Regions, Genetic; Retroviridae; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1997 |
Antitumor activity of poly(L-glutamic acid)-paclitaxel on syngeneic and xenografted tumors.
Topics: Animals; Carcinoma, Hepatocellular; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Female; Humans; Liver Neoplasms, Experimental; Mammary Neoplasms, Animal; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Paclitaxel; Polyglutamic Acid; Sarcoma, Experimental; Taxoids; Transplantation, Heterologous; Transplantation, Homologous; Tumor Cells, Cultured | 1999 |
Hyperthermia enhances the response of paclitaxel and radiation in a mouse adenocarcinoma.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Screening Assays, Antitumor; Female; Hyperthermia, Induced; Mammary Neoplasms, Animal; Mice; Paclitaxel; Radiation-Sensitizing Agents; Radiobiology | 1999 |
Derivation and initial characterization of a mouse mammary tumor cell line carrying the polyomavirus middle T antigen: utility in the development of novel cancer therapeutics.
Topics: Adenoviridae; Alkyl and Aryl Transferases; Animals; Antigens, Polyomavirus Transforming; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Bridged-Ring Compounds; Cell Division; Cisplatin; Deoxycytidine; Dose-Response Relationship, Drug; Farnesyltranstransferase; Female; Gemcitabine; Gene Transfer Techniques; Genes, p53; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Phosphoric Monoester Hydrolases; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Sequence Analysis, DNA; Taxoids; Time Factors; Transduction, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2000 |
Induction of proinflammatory and chemokine genes by lipopolysaccharide and paclitaxel (Taxol) in murine and human breast cancer cell lines.
Topics: Animals; Breast Neoplasms; Chemokine CXCL10; Chemokine CXCL2; Chemokines; Chemokines, CXC; Coculture Techniques; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; Macrophages; Mammary Neoplasms, Animal; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Tumor Cells, Cultured; Up-Regulation | 2001 |
Characterization of isotype-specific regions of five classes of canine beta-tubulin and their expression in several tissues and cell culture.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Dog Diseases; Dogs; Female; Gene Expression Regulation, Neoplastic; Male; Mammary Neoplasms, Animal; Mice; Mice, SCID; Molecular Sequence Data; Osteosarcoma; Paclitaxel; Polymerase Chain Reaction; Protein Isoforms; Sequence Homology, Amino Acid; Tubulin; Tumor Cells, Cultured | 2001 |