p-chloroamphetamine has been researched along with Serotonin Syndrome in 2 studies
p-Chloroamphetamine: Chlorinated analog of AMPHETAMINE. Potent neurotoxin that causes release and eventually depletion of serotonin in the CNS. It is used as a research tool.
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lamotrigine is a novel anticonvulsant drug which also stabilises mood in bipolar illness via an unknown mechanism." | 1.30 | Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats. ( Hagan, RM; Higgins, GA; Kirkby, D; Southam, E, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smalla, KH | 1 |
| Sahin, J | 1 |
| Putzke, J | 1 |
| Tischmeyer, W | 1 |
| Gundelfinger, ED | 1 |
| Kreutz, MR | 1 |
| Southam, E | 1 |
| Kirkby, D | 1 |
| Higgins, GA | 1 |
| Hagan, RM | 1 |
2 other studies available for p-chloroamphetamine and Serotonin Syndrome
| Article | Year |
|---|---|
Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis.
Topics: Animals; Blotting, Western; Calcium-Binding Proteins; Excitatory Amino Acid Antagonists; Ketamine; M | 2009 |
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; | 1998 |