p-chloroamphetamine has been researched along with Disease Models, Animal in 13 studies
p-Chloroamphetamine: Chlorinated analog of AMPHETAMINE. Potent neurotoxin that causes release and eventually depletion of serotonin in the CNS. It is used as a research tool.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Daily injection of 25 microg/100 gm body weight L-thyroxine (T4, Sigma-Aldrich) for 14 days was performed in 14 rats to induce hyperthyroidism." | 3.75 | An experimental approach to the interrelationship between hyperthyroidism and ejaculation latency time in male rats. ( Aslan, G; Cihan, A; Demir, O; Demir, T; Esen, AA; Gidener, S; Murat, N, 2009) |
| "A challenge in drug dependence is to delineate long-term neurochemical modifications induced by drugs of abuse." | 1.35 | Drugs of abuse specifically sensitize noradrenergic and serotonergic neurons via a non-dopaminergic mechanism. ( Glowinski, J; Lanteri, C; Salomon, L; Tassin, JP; Torrens, Y, 2008) |
| "Citalopram prevented the increase in sucrose consumption in the PCA+CVS rats, and in 5-HT-depleted animals blocked the increase in struggling and reduced the number of defecations in the forced swim test." | 1.35 | Rat behavior after chronic variable stress and partial lesioning of 5-HT-ergic neurotransmission: effects of citalopram. ( Eller, M; Häidkind, R; Harro, J; Kõiv, K; Mällo, T; Tõnissaar, M, 2008) |
| "Diazepam was used as a reference compound." | 1.33 | The anxiolytic-like effect of 5-HT1B receptor ligands in rats: a possible mechanism of action. ( Chojnacka-Wójcik, E; Kłodzińska, A; Tatarczyńska, E, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 9 (69.23) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Furlong, TM | 1 |
| Leavitt, LS | 1 |
| Keefe, KA | 1 |
| Son, JH | 1 |
| Cihan, A | 1 |
| Murat, N | 1 |
| Demir, O | 1 |
| Aslan, G | 1 |
| Demir, T | 1 |
| Gidener, S | 1 |
| Esen, AA | 1 |
| Maneepak, M | 1 |
| le Grand, S | 1 |
| Srikiatkhachorn, A | 1 |
| Wang, JL | 1 |
| Oya, S | 1 |
| Parhi, AK | 1 |
| Lieberman, BP | 1 |
| Ploessl, K | 1 |
| Hou, C | 1 |
| Kung, HF | 1 |
| Iyengar, S | 1 |
| Webster, AA | 1 |
| Hemrick-Luecke, SK | 1 |
| Xu, JY | 1 |
| Simmons, RM | 1 |
| Chojnacka-Wójcik, E | 2 |
| Kłodzińska, A | 1 |
| Tatarczyńska, E | 2 |
| Grider, MH | 1 |
| Mamounas, LA | 1 |
| Le, W | 1 |
| Shine, HD | 1 |
| Lanteri, C | 1 |
| Salomon, L | 1 |
| Torrens, Y | 1 |
| Glowinski, J | 1 |
| Tassin, JP | 1 |
| Tõnissaar, M | 2 |
| Mällo, T | 1 |
| Eller, M | 2 |
| Häidkind, R | 1 |
| Kõiv, K | 2 |
| Harro, J | 2 |
| Kanarik, M | 1 |
| Matrov, D | 1 |
| Knott, PJ | 1 |
| Hutson, PH | 1 |
| Przegaliński, E | 1 |
| Filip, M | 1 |
| Hsieh, MT | 1 |
| Lin, YT | 1 |
| Lin, YH | 1 |
| Wu, CR | 1 |
13 other studies available for p-chloroamphetamine and Disease Models, Animal
| Article | Year |
|---|---|
Methamphetamine-, d-Amphetamine-, and p-Chloroamphetamine-Induced Neurotoxicity Differentially Effect Impulsive Responding on the Stop-Signal Task in Rats.
Topics: Animals; Body Temperature; Brain; Central Nervous System Stimulants; Dextroamphetamine; Disease Mode | 2016 |
An experimental approach to the interrelationship between hyperthyroidism and ejaculation latency time in male rats.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Ejaculation; Hyperthyroidism; Injections, Int | 2009 |
Serotonin depletion increases nociception-evoked trigeminal NMDA receptor phosphorylation.
Topics: Animals; Disease Models, Animal; Male; Oncogene Proteins v-fos; p-Chloroamphetamine; Pain; Phosphory | 2009 |
In vivo studies of the SERT-selective [18F]FPBM and VMAT2-selective [18F]AV-133 radiotracers in a rat model of Parkinson's disease.
Topics: Aniline Compounds; Animals; Autoradiography; Disease Models, Animal; Fluorine Radioisotopes; Male; p | 2010 |
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cycl | 2004 |
The anxiolytic-like effect of 5-HT1B receptor ligands in rats: a possible mechanism of action.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzamides; Conflict, Psychological; Diazepam; Disea | 2005 |
In situ expression of brain-derived neurotrophic factor or neurotrophin-3 promotes sprouting of cortical serotonergic axons following a neurotoxic lesion.
Topics: Animals; Brain Diseases; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Disease Models, Animal; | 2005 |
Drugs of abuse specifically sensitize noradrenergic and serotonergic neurons via a non-dopaminergic mechanism.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Disease Models, Animal; Dopamine; Dopamine Agen | 2008 |
Rat behavior after chronic variable stress and partial lesioning of 5-HT-ergic neurotransmission: effects of citalopram.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Biogenic Monoamines; Brain Injuries; Cital | 2008 |
Changes in regional long-term oxidative metabolism induced by partial serotonergic denervation and chronic variable stress in rat brain.
Topics: Adaptation, Physiological; Animals; Brain; Chronic Disease; Denervation; Depressive Disorder; Diseas | 2008 |
Stress-induced stereotypy in the rat: neuropharmacological similarities to Tourette syndrome.
Topics: Animals; Disease Models, Animal; Fenfluramine; Fluoxetine; Humans; Male; Nervous System; p-Chloroamp | 1982 |
The role of 5-hydroxytryptamine1A (5-HT1A) receptors in the anticonflict activity of beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Animals; Anxiety; Betaxolol; Conflict, Psychological; Disease Models, A | 1994 |
Radix Angelica Sinensis extracts ameliorate scopolamine- and cycloheximide-induced amnesia, but not p-chloroamphetamine-induced amnesia in rats.
Topics: Amnesia; Animals; Apiaceae; Behavior, Animal; Cycloheximide; Disease Models, Animal; Drugs, Chinese | 2000 |