p-aminohippuric acid has been researched along with Renal Insufficiency in 14 studies
p-Aminohippuric Acid: The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.
p-aminohippurate : A hippurate that is the conjugate base of p-aminohippuric acid, arising from deprotonation of the carboxy group.
p-aminohippuric acid : An N-acylglycine that is the 4-amino derivative of hippuric acid; used as a diagnostic agent in the measurement of renal plasma flow.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ischemic acute renal failure (iARF) was described to reduce renal extraction of the organic anion para-aminohippurate (PAH) in humans." | 1.34 | Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats. ( Betz, B; Fischer, D; Galle, J; Gekle, M; Holzinger, H; Otremba, M; Sauvant, C; Schneider, R; Wanner, C, 2007) |
| " The present study was therefore carried out to determine the mechanism and the exact sequence of events that lead to molecular toxic injury." | 1.31 | Atractyloside nephrotoxicity: in vitro studies with suspensions of rat renal fragments and precision-cut cortical slices. ( Bach, PH; Obatomi, DK, 2000) |
| "Aminoglycoside nephrotoxicity remains a common clinical problem and is the major cause of acute toxic renal failure in hospitalized patients." | 1.29 | Effects of diltiazem on netilmicin-induced nephrotoxicity in rabbits. ( Amirault, P; Blanchet, F; Carbon, C; Heudes, D; Lortholary, O; Nochy, D; Seta, N, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lannemyr, L | 1 |
| Ricksten, SE | 1 |
| Rundqvist, B | 1 |
| Andersson, B | 1 |
| Bartfay, SE | 1 |
| Ljungman, C | 1 |
| Dahlberg, P | 1 |
| Bergh, N | 1 |
| Hjalmarsson, C | 1 |
| Gilljam, T | 1 |
| Bollano, E | 1 |
| Karason, K | 1 |
| FEKETE, A | 2 |
| TARABA, I | 2 |
| VALEK, A | 1 |
| COBURN, JW | 1 |
| GONICK, HC | 1 |
| RUBINI, ME | 1 |
| KLEEMAN, CR | 1 |
| BALINT, P | 1 |
| FORGACS, I | 1 |
| Fuiano, G | 1 |
| Mancuso, D | 1 |
| Indolfi, C | 1 |
| Mongiardo, A | 1 |
| Sabbatini, M | 1 |
| Conte, G | 1 |
| De Nicola, L | 1 |
| Minutolo, R | 1 |
| Mazza, G | 1 |
| Cianfrone, P | 1 |
| Andreucci, M | 1 |
| Schneider, R | 1 |
| Sauvant, C | 1 |
| Betz, B | 1 |
| Otremba, M | 1 |
| Fischer, D | 1 |
| Holzinger, H | 1 |
| Wanner, C | 1 |
| Galle, J | 1 |
| Gekle, M | 1 |
| Itkin, RJ | 2 |
| Krawiec, DR | 2 |
| Twardock, AR | 2 |
| Gelberg, HB | 2 |
| Koritz, GD | 1 |
| Lortholary, O | 1 |
| Blanchet, F | 1 |
| Nochy, D | 1 |
| Heudes, D | 1 |
| Seta, N | 1 |
| Amirault, P | 1 |
| Carbon, C | 1 |
| Kuwabara, T | 1 |
| Ishikawa, Y | 1 |
| Kobayashi, H | 1 |
| Kobayashi, S | 1 |
| Sugiyama, Y | 1 |
| Easterling, TR | 1 |
| Van Hook, J | 1 |
| Roberts, B | 1 |
| Koerker, D | 1 |
| Obatomi, DK | 1 |
| Bach, PH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Intravenous Levosimendan Compared With Dobutamine on Renal Hemodynamics and Function in Chronic Heart Failure[NCT02133105] | Phase 3 | 33 participants (Actual) | Interventional | 2014-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for p-aminohippuric acid and Renal Insufficiency
| Article | Year |
|---|---|
Differential Effects of Levosimendan and Dobutamine on Glomerular Filtration Rate in Patients With Heart Failure and Renal Impairment:A Randomized Double-Blind Controlled Trial.
Topics: Aged; Cardio-Renal Syndrome; Cardiotonic Agents; Dobutamine; Double-Blind Method; Female; Glomerular | 2018 |
Early detection of progressive renal dysfunction in patients with coronary artery disease.
Topics: Amino Acids; Coronary Artery Disease; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; | 2005 |
12 other studies available for p-aminohippuric acid and Renal Insufficiency
| Article | Year |
|---|---|
[CHANGES IN THE KIDNEY FUNCTION FOLLOWING PROCAINE INFILTRATION IN ACUTE KIDNEY DAMAGE].
Topics: Acute Kidney Injury; Anuria; Blood; Dogs; Kidney Function Tests; Nephrectomy; Nephritis; Nitrogen; p | 1964 |
ACUTE RENAL INSUFFICIENCY IN INTOXICATION WITH MERCURY COMPOUNDS. I. AETIOLOGY, CLINICAL PICTURE, RENAL FUNCTION.
Topics: Acute Kidney Injury; Anuria; Creatine; Creatinine; Inulin; Kidney Function Tests; Mercury Compounds; | 1965 |
STUDIES OF EXPERIMENTAL RENAL FAILURE IN DOGS. I. EFFECT OF 5-6 NEPHRECTOMY ON CONCENTRATING AND DILUTING CAPACITY OF RESIDUAL NEPHRONS.
Topics: Creatine; Creatinine; Diuresis; Dogs; Fluids and Secretions; Glomerular Filtration Rate; Kidney Dise | 1965 |
CHANGES IN RENAL FUNCTION AFTER PROCAINE TREATMENT IN ACUTE RENAL FAILURE.
Topics: Acute Kidney Injury; Anuria; Blood Pressure; Blood Pressure Determination; Dogs; Inulin; p-Aminohipp | 1965 |
ON THE MECHANISM OF RENAL FAILURE IN DEHYDRATION.
Topics: Acute Kidney Injury; Blood Pressure; Dehydration; Dogs; Kidney; Oximetry; p-Aminohippuric Acid; Rena | 1965 |
Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats.
Topics: Animals; Blotting, Western; Down-Regulation; Female; Inulin; Ischemia; Kidney; Organic Anion Transpo | 2007 |
Evaluation of the single-injection plasma disappearance of technetium-99m mercaptoacetyltriglycine method for determination of effective renal plasma flow in dogs with normal or abnormal renal function.
Topics: Animals; Dog Diseases; Dogs; Erythrocytes; Female; Kidney Function Tests; Male; p-Aminohippuric Acid | 1994 |
Quantitative renal scintigraphic determination of effective renal plasma flow in dogs with normal and abnormal renal function, using 99mTc-mercaptoacetyltriglycine.
Topics: Animals; Dog Diseases; Dogs; Female; Male; p-Aminohippuric Acid; Radionuclide Imaging; Reference Val | 1994 |
Effects of diltiazem on netilmicin-induced nephrotoxicity in rabbits.
Topics: Aldosterone; Animals; Blood Gas Analysis; Diltiazem; Gases; Inulin; Kidney; Kidney Function Tests; K | 1993 |
Renal clearance of a recombinant granulocyte colony-stimulating factor, nartograstim, in rats.
Topics: Animals; Cisplatin; Glomerular Filtration Rate; Granulocyte Colony-Stimulating Factor; Half-Life; Hu | 1995 |
The central and renal hemodynamic effects of amino acid infusion in the study of renal reserve in the baboon.
Topics: Amino Acids; Animals; Diabetic Nephropathies; Disease Models, Animal; Female; Glomerular Filtration | 1998 |
Atractyloside nephrotoxicity: in vitro studies with suspensions of rat renal fragments and precision-cut cortical slices.
Topics: Adenosine Triphosphate; Animals; Atractyloside; Biological Transport; Cell Death; Dose-Response Rela | 2000 |