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p-aminohippuric acid and Proteinuria

p-aminohippuric acid has been researched along with Proteinuria in 38 studies

p-Aminohippuric Acid: The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.
p-aminohippurate : A hippurate that is the conjugate base of p-aminohippuric acid, arising from deprotonation of the carboxy group.
p-aminohippuric acid : An N-acylglycine that is the 4-amino derivative of hippuric acid; used as a diagnostic agent in the measurement of renal plasma flow.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"However, after 6 mo of Valsartan treatment, proteinuria was reduced by 396 +/- 323 mg/24 h (26 +/- 18%) and albuminuria by 531 +/- 499 mg/24 h (41 +/- 21%) with regard to baseline values (P < 0."6.69Effects of the angiotensin II antagonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients with chronic renal failure and hypertension. ( Bünten, B; Grabensee, B; Németh, R; Plum, J, 1998)
"8 mmol/kg) was characterized by diuresis, transiently increased proteinuria, glucosuria and hematuria elevated kidney weight and reduced tetraethylammonium (TEA) uptake by renal cortical slices, and was not as marked as nephrotoxicity induced by NDHS (0."3.69Nephrotoxicity of N-(3-bromophenyl)-2-hydroxysuccinimide: role of halogen groups in the nephrotoxic potential of N-(halophenyl) succinimides. ( Anestis, DK; Brown, PI; Hawco, NM; Hong, SK; Rankin, GO; Valentovic, MA, 1996)
"However, after 6 mo of Valsartan treatment, proteinuria was reduced by 396 +/- 323 mg/24 h (26 +/- 18%) and albuminuria by 531 +/- 499 mg/24 h (41 +/- 21%) with regard to baseline values (P < 0."2.69Effects of the angiotensin II antagonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients with chronic renal failure and hypertension. ( Bünten, B; Grabensee, B; Németh, R; Plum, J, 1998)
"Proteinuria was determined in the course of a three-day collection period at the end of each treatment phase."2.68[Renal hemodynamics and proteinuria in chronic glomerulonephritis treated with beta-receptor blockers or ace inhibitors]. ( Berger, ED; Braun, N; Erley, CM; Heyne, N; Klass, M; Krämer, D; Risler, T; Wolf, S, 1997)
"Hyperuricemia has been reported to affect renal hemodynamics in rat models."1.42Relationship between serum uric acid levels and intrarenal hemodynamic parameters. ( Ichii, M; Inaba, M; Ishimura, E; Mori, K; Nakatani, S; Nakatani, T; Ochi, A; Ohno, Y; Tsuda, A; Uchida, J; Uedono, H; Yasumoto, M, 2015)
" The mechanism of protection conferred to rats by an ADT pretreatment against HCBD-induced nephrotoxicity appears to take place in the kidney at a step beyond the generation of ultimate toxic metabolites derived from PCBC."1.29Assessment of the role of glutathione conjugation in the protection afforded by anethol dithiolthione against hexachloro-1,3-butadiene-induced nephrotoxicity. ( Bouthillier, L; Brodeur, J; Charbonneau, M, 1996)
"As phenobarbital treatment in young rats enhanced the symptoms of nephrotoxicity and metyrapone treatment in adult rats decreased the symptoms of nephrotoxicity, age-dependent differences in chromate nephrotoxicity may be linked to an increase in the enzymatic reduction of Cr(VI) with age."1.28Influence of metyrapone and phenobarbital on sodium dichromate nephrotoxicity in developing rats. ( Appenroth, D; Bräunlich, H; Friese, KH; Gambaryan, S, 1990)
"Treatment with enalapril normalized BP, corrected electrolyte abnormalities, and reduced proteinuria."1.28Angiotensin-converting enzyme inhibition ameliorates the defect in glomerular size selectivity in hyponatremic hypertensive syndrome. ( Battaglia, C; Remuzzi, A; Remuzzi, G; Schieppati, A, 1989)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199021 (55.26)18.7374
1990's14 (36.84)18.2507
2000's2 (5.26)29.6817
2010's1 (2.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uedono, H1
Tsuda, A1
Ishimura, E1
Yasumoto, M1
Ichii, M1
Ochi, A1
Ohno, Y1
Nakatani, S1
Mori, K1
Uchida, J1
Nakatani, T1
Inaba, M1
Appenroth, D2
Beutinger, R1
Lupp, A1
Fleck, C1
CORA, D1
DEBIASI, S1
ZAGARESE, R1
SMYTHE, CM1
BRADHAM, WS1
DENNIS, EJ1
MCIVER, FA1
HOWE, HG1
BRODWALL, EK2
LAAKE, H1
JOACHIM, GR1
CAMERON, JS1
SCHWARTZ, M1
BECKER, EL1
Baylis, C1
Atzpodien, EA1
Freshour, G1
Engels, K1
Wüstenberg, PW1
Dörp, E1
Sinn, W1
Mücke, D1
Wulf, E1
Braunlich, H2
Kuo, CH1
Slocombe, R1
Hook, JB1
Rankin, GO7
Cressey-Veneziano, K1
Brown, PI7
Suzuki, CA1
Hierlihy, L1
Barker, M1
Curran, I1
Mueller, R1
Bondy, GS1
Valentovic, MA4
Nicoll, DW3
Ball, JG3
Anestis, DK4
Wang, RT1
Threefoot, SA1
De Cosmo, S1
Earle, K1
Morocutti, A1
Walker, J1
Ruggenenti, P1
Remuzzi, G2
Viberti, GC1
Hong, SK3
Hawco, NM1
Bouthillier, L1
Charbonneau, M1
Brodeur, J1
Fuiano, G1
Esposito, C1
Sepe, V1
Colucci, G1
Bovino, M1
Rosa, M1
Balletta, M1
Bellinghieri, G1
Conte, G1
Cianciaruso, B1
Dal Canton, A1
Erley, CM1
Berger, ED1
Heyne, N1
Klass, M1
Krämer, D1
Braun, N1
Wolf, S1
Risler, T1
Hannemann, J1
Wunderle, W1
Yousif, T1
Krüger, S1
Baumann, K1
Beers, KW1
Plum, J1
Bünten, B1
Németh, R1
Grabensee, B1
Diézi, J1
Biollaz, J1
Cuppage, FE1
Setter, K1
Sullivan, P1
Reitzes, EJ1
Melnykovych, AO1
Bauman, JW1
Gambaryan, S1
Friese, KH1
Thaiss, F1
Schoeppe, W1
Germann, P1
Stahl, RA1
Tomlanovich, S1
Deen, WM1
Jones, HW1
Schwartz, HC1
Myers, BD1
Remuzzi, A1
Schieppati, A1
Battaglia, C1
Ishi, M1
Hirata, Y1
Sugimoto, T2
Matsuoka, H1
Kimura, K1
Ishimitsu, T1
Fukui, K1
Kurosawa, Y1
Kiyose, H1
Teets, VJ2
Elliott, C1
Madan, E1
Yang, DJ1
Lo, HH1
Heifets, M1
Morrissey, JJ1
Purkerson, ML1
Morrison, AR1
Klahr, S1
Bovee, KC1
Beauchamp, D1
Poirier, A1
Bergeron, MG1
Maitani, T1
Watahiki, A1
Suzuki, KT1

Reviews

1 review available for p-aminohippuric acid and Proteinuria

ArticleYear
Renal function tests in experimental toxicity studies.
    Pharmacology & therapeutics. Part B: General & systematic pharmacology, 1979, Volume: 5, Issue:1-3

    Topics: Animals; Diuresis; Drug Evaluation, Preclinical; Electrolytes; Enzymes; Glomerular Filtration Rate;

1979

Trials

4 trials available for p-aminohippuric acid and Proteinuria

ArticleYear
Glucose-induced changes in renal haemodynamics in proteinuric type 1 (insulin-dependent) diabetic patients: inhibition by acetylsalicilic acid infusion.
    Diabetologia, 1993, Volume: 36, Issue:7

    Topics: Adult; Analysis of Variance; Aspirin; Biopsy; Blood Proteins; Diabetes Mellitus, Type 1; Diabetic Ne

1993
Effects of hypercholesterolemia of renal hemodynamics: study in patients with nephrotic syndrome.
    Nephron, 1996, Volume: 73, Issue:3

    Topics: Adult; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Inulin; Kidney Function Tests

1996
[Renal hemodynamics and proteinuria in chronic glomerulonephritis treated with beta-receptor blockers or ace inhibitors].
    Deutsche medizinische Wochenschrift (1946), 1997, Aug-01, Volume: 122, Issue:31-32

    Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agent

1997
Effects of the angiotensin II antagonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients with chronic renal failure and hypertension.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:12

    Topics: Aged; Albuminuria; Angiotensin II; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Cre

1998

Other Studies

33 other studies available for p-aminohippuric acid and Proteinuria

ArticleYear
Relationship between serum uric acid levels and intrarenal hemodynamic parameters.
    Kidney & blood pressure research, 2015, Volume: 40, Issue:3

    Topics: Adult; Aged; Algorithms; Blood Pressure; Diabetic Nephropathies; Female; Glomerular Filtration Rate;

2015
Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2003, Volume: 54, Issue:5-6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Disease

2003
[Increas'e of proteinuria in the course of tubular saturation with p-aminohippuric acid].
    Il Progresso medico, 1958, Aug-15, Volume: 14, Issue:15

    Topics: Humans; Hypertension; Kidney Diseases; p-Aminohippuric Acid; Proteinuria

1958
RENAL ARTERIOLAR DISEASE IN YOUNG PRIMIPARAS.
    The Journal of laboratory and clinical medicine, 1964, Volume: 63

    Topics: Adolescent; Arteries; Black People; Blood Chemical Analysis; Body Weight; Eclampsia; Female; Humans;

1964
THE RELATION BETWEEN OXYGEN CONSUMPTION AND TRANSPORT OF SODIUM IN THE HUMAN KIDNEY.
    Scandinavian journal of clinical and laboratory investigation, 1964, Volume: 16

    Topics: Amyloidosis; Arteritis; Biological Transport; Celiac Disease; Diabetes Mellitus; Diabetic Nephropath

1964
THE RELATION BETWEEN THE RENAL OXYGEN CONSUMPTION AND THE TRANSPORT OF SODIUM, CLEARANCE OF INULIN AND THE RENAL EXTRACTION OF PAH.
    Scandinavian journal of clinical and laboratory investigation, 1964, Volume: 16

    Topics: Amyloidosis; Arteritis; Biological Transport; Celiac Disease; Diabetes Mellitus; Diabetic Nephropath

1964
SELECTIVITY OF PROTEIN EXCRETION IN PATIENTS WITH THE NEPHROTIC SYNDROME.
    The Journal of clinical investigation, 1964, Volume: 43

    Topics: Amyloidosis; Blood Proteins; Diabetes Mellitus; Drug Therapy; Glomerulonephritis; Humans; Immunodiff

1964
Peroxisome proliferator-activated receptor [gamma] agonist provides superior renal protection versus angiotensin-converting enzyme inhibition in a rat model of type 2 diabetes with obesity.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Body Weight; Diabetes Complication

2003
[Methodologic references for clinical function diagnosis of glomerular permeability selectivity by molecular wight related protein analysis and additional para-aminohippuric acid load].
    Zeitschrift fur Urologie und Nephrologie, 1984, Volume: 77, Issue:10

    Topics: Aminohippuric Acids; Capillary Permeability; Glomerular Filtration Rate; Humans; Kidney Function Tes

1984
cis-Dichlorodiammineplatinum nephrotoxicity in rats of different ages.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 44, Issue:2

    Topics: Age Factors; Animals; Blood Urea Nitrogen; Body Weight; Cisplatin; Dose-Response Relationship, Drug;

1984
Onset of and recovery from acute N-(3,5-dichlorophenyl)succinimide-induced nephrotoxicity in Sprague-Dawley rats.
    Toxicology, 1984, Apr-02, Volume: 30, Issue:3

    Topics: Animals; Blood Urea Nitrogen; Diuresis; Hematuria; Kidney Diseases; Kidney Tubules, Proximal; Male;

1984
The effects of fumonisin B1 on several markers of nephrotoxicity in rats.
    Toxicology and applied pharmacology, 1995, Volume: 133, Issue:2

    Topics: Animals; Biomarkers; Carcinogens, Environmental; Creatinine; Electrophoresis, Polyacrylamide Gel; Fl

1995
In vivo and in vitro 4-amino-2,6-dichlorophenol nephrotoxicity and hepatotoxicity in the Fischer 344 rat.
    Toxicology, 1994, May-31, Volume: 90, Issue:1-2

    Topics: Alanine Transaminase; Animals; Blood Urea Nitrogen; Chlorophenols; Gluconeogenesis; Glycosuria; Hema

1994
Influence of obstructed renal lymph flow on effects of a nephrotoxin on renal function.
    Lymphology, 1993, Volume: 26, Issue:4

    Topics: Animals; Body Water; Creatinine; Dogs; Electrolytes; Female; Kidney; Lymphatic System; Organometalli

1993
Nephrotoxicity of N-(3-bromophenyl)-2-hydroxysuccinimide: role of halogen groups in the nephrotoxic potential of N-(halophenyl) succinimides.
    Toxicology, 1996, Jun-17, Volume: 110, Issue:1-3

    Topics: Analysis of Variance; Animals; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Fungicides, Ind

1996
Assessment of the role of glutathione conjugation in the protection afforded by anethol dithiolthione against hexachloro-1,3-butadiene-induced nephrotoxicity.
    Toxicology and applied pharmacology, 1996, Volume: 139, Issue:1

    Topics: Anethole Trithione; Animals; Bile; Binding Sites; Butadienes; Cholagogues and Choleretics; Cysteine;

1996
Toxic effect of concomitant administration of cyclosporin A and acyclovir on renal function and morphology in rats.
    Archives of toxicology, 1997, Volume: 71, Issue:9

    Topics: Acetylglucosaminidase; Acyclovir; Animals; Antiviral Agents; Blood Urea Nitrogen; Body Weight; Creat

1997
Effects of sodium sulfate on acute N-(3,5-dichlorophenyl)succinimide (NDPS) nephrotoxicity in the Fischer 344 rat.
    Toxicology, 1997, Nov-21, Volume: 123, Issue:1-2

    Topics: Animals; Biotransformation; Blood Urea Nitrogen; Diuresis; Drug Synergism; Fungicides, Industrial; K

1997
Effect of glucuronidation substrates/inhibitors on N-(3,5-dichlorophenyl)succinimide nephrotoxicity in Fischer 344 rats.
    Toxicology, 1999, Jan-01, Volume: 132, Issue:1

    Topics: Animals; Biotransformation; Blood Urea Nitrogen; Camphanes; Clofibric Acid; Drinking; Eating; Eugeno

1999
Gentamicin nephrotoxicity. II. Physiological, biochemical and morphological effects of prolonged administration to rats.
    Virchows Archiv. B, Cell pathology, 1977, Jun-24, Volume: 24, Issue:2

    Topics: Animals; Blood Urea Nitrogen; Gentamicins; Glomerular Filtration Rate; Kidney; Male; Microscopy, Ele

1977
Corticoid effects on angiotensin- and norepinephrine-induced proteinuria in rats.
    The American journal of physiology, 1979, Volume: 237, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Dexamethasone; Female; Inulin; Norepinephrine; p-Aminohippuric

1979
Influence of metyrapone and phenobarbital on sodium dichromate nephrotoxicity in developing rats.
    Journal of applied toxicology : JAT, 1990, Volume: 10, Issue:3

    Topics: Aging; Animals; Chromates; Chromium; Cromolyn Sodium; Female; Kidney; Kidney Diseases; Kidney Tubule

1990
Dietary fish oil intake: effects on glomerular prostanoid formation, hemodynamics, and proteinuria in nephrotoxic serum nephritis.
    The Journal of laboratory and clinical medicine, 1990, Volume: 116, Issue:2

    Topics: Animals; Diet; Dinoprostone; Eicosanoids; Fish Oils; Glomerular Filtration Rate; Hemodynamics; Immun

1990
Functional nature of glomerular injury in progressive diabetic glomerulopathy.
    Diabetes, 1987, Volume: 36, Issue:5

    Topics: Adult; Aged; Capillaries; Cell Membrane; Creatinine; Dextrans; Diabetes Mellitus, Type 1; Diabetic N

1987
Angiotensin-converting enzyme inhibition ameliorates the defect in glomerular size selectivity in hyponatremic hypertensive syndrome.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 14, Issue:3

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Dextrans; Enalapril; Glomerular Filtration Rate; Hum

1989
Effect of alpha-human atrial natriuretic peptide on proteinuria in patients with primary glomerular diseases.
    Clinical science (London, England : 1979), 1989, Volume: 77, Issue:6

    Topics: Adolescent; Adult; Aged; Albuminuria; Atrial Natriuretic Factor; Creatinine; Female; Glomerular Filt

1989
Comparative acute renal effects of three N-(3,5-dichlorophenyl)carboximide fungicides: N-(3,5-dichlorophenyl)succinimide, vinclozolin and iprodione.
    Toxicology, 1989, Jun-16, Volume: 56, Issue:3

    Topics: Aminoimidazole Carboxamide; Animals; Blood Urea Nitrogen; Diuresis; Drinking; Eating; Fungicides, In

1989
Cephaloridine nephrotoxicity in streptozotocin induced diabetic Fischer 344 (F344) rats.
    Toxicology, 1989, Jul-17, Volume: 57, Issue:2

    Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Cephaloridine; Diabetes Mellitus, Experimental; Glycosu

1989
Structure-nephrotoxicity relationships for meta-substituted N-phenylsuccinimides.
    Journal of applied toxicology : JAT, 1987, Volume: 7, Issue:3

    Topics: Animals; Blood Urea Nitrogen; Diuresis; Electrons; Fungicides, Industrial; Hematuria; Kidney; Male;

1987
Effect of dietary lipids on renal function in rats with subtotal nephrectomy.
    Kidney international, 1987, Volume: 32, Issue:3

    Topics: Animals; Blood Pressure; Body Weight; Dietary Fats; Fatty Acids; Female; Inulin; Kidney; Kidney Func

1987
Renal function and laboratory evaluation.
    Toxicologic pathology, 1986, Volume: 14, Issue:1

    Topics: Amino Acids; Animals; Blood Chemical Analysis; Glomerular Filtration Rate; Glucose; Humans; Kidney;

1986
Increased nephrotoxicity of gentamicin in pyelonephritic rats.
    Kidney international, 1985, Volume: 28, Issue:2

    Topics: Animals; beta-Galactosidase; Diuresis; Escherichia coli Infections; Female; Gentamicins; Glomerular

1985
Acute renal dysfunction by cadmium injected with cysteine in relation to renal critical concentration of cadmium.
    Archives of toxicology, 1986, Volume: 58, Issue:3

    Topics: Animals; Cadmium; Calcium; Cysteine; Dose-Response Relationship, Drug; Glycosuria; Kidney; Kidney Di

1986