p-aminohippuric acid has been researched along with Kidney Failure, Chronic in 29 studies
p-Aminohippuric Acid: The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.
p-aminohippurate : A hippurate that is the conjugate base of p-aminohippuric acid, arising from deprotonation of the carboxy group.
p-aminohippuric acid : An N-acylglycine that is the 4-amino derivative of hippuric acid; used as a diagnostic agent in the measurement of renal plasma flow.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, after 6 mo of Valsartan treatment, proteinuria was reduced by 396 +/- 323 mg/24 h (26 +/- 18%) and albuminuria by 531 +/- 499 mg/24 h (41 +/- 21%) with regard to baseline values (P < 0." | 6.69 | Effects of the angiotensin II antagonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients with chronic renal failure and hypertension. ( Bünten, B; Grabensee, B; Németh, R; Plum, J, 1998) |
| "Fenofibrate is a potent hypolipemic agent, widely used in patients with mild to severe renal failure in whom hyperlipoproteinemia is frequent." | 5.09 | [Fenofibrate increases blood creatinine, but does not change the glomerular filtration rate in patients with mild renal insufficiency]. ( Achard, JM; el Esper, N; Fournier, A; Hottelart, C; Pruna, A, 1999) |
| " 51Chromium-ethylenediamine tetraacetic acid, para-amino hippuric acid, lithium, and sodium clearances, measurements of serum and urinary electrolytes, and urinary concentration tests were performed." | 3.69 | Kidney function in cyclosporine-treated pediatric heart transplant recipients. ( Holmberg, C; Jalanko, H; Laine, J; Leijala, M; Sairanen, H, 1997) |
| "However, after 6 mo of Valsartan treatment, proteinuria was reduced by 396 +/- 323 mg/24 h (26 +/- 18%) and albuminuria by 531 +/- 499 mg/24 h (41 +/- 21%) with regard to baseline values (P < 0." | 2.69 | Effects of the angiotensin II antagonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients with chronic renal failure and hypertension. ( Bünten, B; Grabensee, B; Németh, R; Plum, J, 1998) |
| "The progress of chronic renal failure (CRF) is characterized by the development of glomerular and tubular lesions." | 1.33 | Altered renal elimination of organic anions in rats with chronic renal failure. ( Anzai, N; Brandoni, A; Endou, H; Mac Laughlin, M; Mónica Torres, A; Muller, A, 2005) |
| "However, their changes in chronic renal failure (CRF) are poorly understood." | 1.31 | Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy. ( Inui, K; Ji, L; Masuda, S; Saito, H, 2002) |
| "End-state renal disease (ESRD) affects 300000 people in the United States each year." | 1.31 | High-throughput multi-analyte screening for renal disease using capillary electrophoresis. ( Clark, EA; Fanguy, JC; Henry, CS, 2001) |
| " Serum IGFBP-3 levels fell while IGFBP-1 and -2 levels rose during treatment, changes that likely affect the bioavailability of IGF-I." | 1.30 | Early experience with extended use of insulin-like growth factor-1 in advanced chronic renal failure. ( Fervenza, FC; Hintz, RL; Hoffman, AR; Ike, JO; Liu, F; Rabkin, R; Yeh, I, 1997) |
| "Ten patients with chronic renal failure whose hypertension was controlled with triple drug therapy consisting of propranolol-hydralazine-furosemide were switched to the angiotensin-converting enzyme (ACE) inhibitor captopril for a period of 12 months." | 1.28 | Converting enzyme inhibition in chronic renal failure. ( Miranda, B; Morales, JM; Raij, L; Rodicio, JL; Romero, JC; Ruilope, LM, 1989) |
| " The dose-response curve is similar to that of a known competitive inhibitor, hippuric acid, and the average inhibitory activity of uremic extract as derived from these curves was 3." | 1.26 | Suppression of tubular anion transport by an inhibitor of serum protein binding in uremia. ( Depner, TA, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.69) | 18.7374 |
| 1990's | 13 (44.83) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ji, L | 1 |
| Masuda, S | 1 |
| Saito, H | 1 |
| Inui, K | 1 |
| Agarwal, R | 1 |
| Vasavada, N | 1 |
| Chase, SD | 1 |
| Appenroth, D | 2 |
| Beutinger, R | 1 |
| Lupp, A | 1 |
| Fleck, C | 2 |
| Sutter, L | 1 |
| Koch, B | 1 |
| Meinhold, T | 1 |
| Pitack, M | 1 |
| Gasser, R | 1 |
| Mónica Torres, A | 1 |
| Mac Laughlin, M | 1 |
| Muller, A | 1 |
| Brandoni, A | 1 |
| Anzai, N | 1 |
| Endou, H | 1 |
| Schwarz, A | 1 |
| Rustien, G | 1 |
| Merkel, S | 1 |
| Radermacher, J | 1 |
| Haller, H | 1 |
| Franz, KA | 1 |
| Reubi, FC | 1 |
| Depner, TA | 1 |
| Yü, TF | 1 |
| Berger, L | 1 |
| Maxwell, H | 1 |
| Nair, DR | 1 |
| Dalton, RN | 1 |
| Rigden, SP | 1 |
| Rees, L | 1 |
| Miller, SB | 2 |
| Moulton, M | 1 |
| O'Shea, M | 1 |
| Hammerman, MR | 2 |
| Prescott, LF | 2 |
| Freestone, S | 2 |
| McAuslane, JA | 2 |
| O'Shea, MH | 1 |
| Cortsen, M | 1 |
| Petersen, LJ | 1 |
| Ståhlberg, F | 1 |
| Thomsen, C | 1 |
| Søndergaard, L | 1 |
| Petersen, JR | 1 |
| Ladefoged, SD | 1 |
| Henriksen, O | 1 |
| Ike, JO | 1 |
| Fervenza, FC | 1 |
| Hoffman, AR | 1 |
| Yeh, I | 1 |
| Hintz, RL | 1 |
| Liu, F | 1 |
| Rabkin, R | 1 |
| Laine, J | 1 |
| Jalanko, H | 1 |
| Leijala, M | 1 |
| Sairanen, H | 1 |
| Holmberg, C | 1 |
| Plum, J | 1 |
| Bünten, B | 1 |
| Németh, R | 1 |
| Grabensee, B | 1 |
| Roy, L | 1 |
| Legault, L | 1 |
| Pomier-Layrargues, G | 1 |
| Hottelart, C | 1 |
| el Esper, N | 1 |
| Achard, JM | 1 |
| Pruna, A | 1 |
| Fournier, A | 1 |
| Pastore, A | 1 |
| Bernardini, S | 1 |
| Dello Strologo, L | 1 |
| Rizzoni, G | 1 |
| Cortese, C | 1 |
| Federici, G | 1 |
| Clark, EA | 1 |
| Fanguy, JC | 1 |
| Henry, CS | 1 |
| Deguchi, T | 1 |
| Ohtsuki, S | 1 |
| Otagiri, M | 1 |
| Takanaga, H | 1 |
| Asaba, H | 1 |
| Mori, S | 1 |
| Terasaki, T | 1 |
| Guidi, E | 1 |
| Minetti, EE | 1 |
| Cozzi, MG | 1 |
| Berg, KJ | 1 |
| Brooks, DP | 1 |
| Goldstein, R | 1 |
| Koster, PF | 1 |
| DePalma, PD | 1 |
| DiCristo, M | 1 |
| Karpinski, K | 1 |
| Hyneck, M | 1 |
| Deray, G | 1 |
| Cacoub, P | 1 |
| Jacquiaud, C | 1 |
| Drobinski, G | 1 |
| Brillet, G | 1 |
| Bunker, D | 1 |
| Jaudon, MC | 1 |
| Jacobs, C | 1 |
| Drobinski, M | 1 |
| Ruilope, LM | 1 |
| Miranda, B | 1 |
| Morales, JM | 1 |
| Rodicio, JL | 1 |
| Romero, JC | 1 |
| Raij, L | 1 |
| Gloff, CA | 1 |
| Benet, LZ | 1 |
6 trials available for p-aminohippuric acid and Kidney Failure, Chronic
| Article | Year |
|---|---|
Differential effects of recombinant human growth hormone on glomerular filtration rate and renal plasma flow in chronic renal failure.
Topics: Adolescent; Blood Pressure; Body Height; Child; Child, Preschool; Creatinine; Female; Glomerular Fil | 1995 |
Effects of IGF-I on renal function in end-stage chronic renal failure.
Topics: Adult; Aged; Female; Glomerular Filtration Rate; Humans; Insulin-Like Growth Factor I; Inulin; Kidne | 1994 |
Effects of the angiotensin II antagonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients with chronic renal failure and hypertension.
Topics: Aged; Albuminuria; Angiotensin II; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Cre | 1998 |
[Fenofibrate increases blood creatinine, but does not change the glomerular filtration rate in patients with mild renal insufficiency].
Topics: Aged; Creatinine; Cross-Over Studies; Female; Fenofibrate; Glomerular Filtration Rate; Humans; Hyper | 1999 |
Acute and long-term effects of ACE inhibition on renal haemodynamics in glomerular and interstitial nephropathies.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Enalapril; Female; Glomerular Filtration Rate; Glom | 2002 |
Effects of tenoxicam on renal function and the disposition of inulin and p-aminohippurate in healthy volunteers and patients with chronic renal failure.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; beta 2-Microglobulin; Dinoprostone; Glomerular Filtr | 1991 |
23 other studies available for p-aminohippuric acid and Kidney Failure, Chronic
| Article | Year |
|---|---|
Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy.
Topics: Animals; Cimetidine; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Estradiol; Gonadal | 2002 |
Liquid chromatography for iothalamate in biological samples.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Calibration; Chromatography, High Pressure Liquid; Contr | 2003 |
Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Disease | 2003 |
Use of gene chip technology for the characterisation of the regulation of renal transport processes and of nephrotoxicity in rats.
Topics: Aging; Animals; Biological Transport; Dexamethasone; Disease Models, Animal; Female; Gene Expression | 2003 |
Altered renal elimination of organic anions in rats with chronic renal failure.
Topics: Animals; Anions; Blood Pressure; Creatinine; Kidney; Kidney Failure, Chronic; Male; Organic Anion Tr | 2005 |
Decreased renal transplant function after parathyroidectomy.
Topics: Biopsy; Calcinosis; Calcium; Creatinine; Female; Follow-Up Studies; Humans; Hyperparathyroidism, Sec | 2007 |
Rate of functional deterioration in polycystic kidney disease.
Topics: Adult; Age Factors; Aged; Chromium Radioisotopes; Creatinine; Edetic Acid; Follow-Up Studies; Glomer | 1983 |
Suppression of tubular anion transport by an inhibitor of serum protein binding in uremia.
Topics: Animals; Biological Transport; Blood Proteins; Humans; Kidney Failure, Chronic; Kidney Tubules; Niac | 1981 |
Impaired renal function gout: its association with hypertensive vascular disease and intrinsic renal disease.
Topics: Adolescent; Adult; Aged; Aging; Coronary Disease; Gout; Humans; Hypertension; Inulin; Kidney; Kidney | 1982 |
The concentration-dependent disposition of intravenous p-aminohippurate in subjects with normal and impaired renal function.
Topics: Acetylation; Adult; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Injections, Intrave | 1993 |
Effects of IGF-I on renal function in patients with chronic renal failure.
Topics: Adolescent; Adult; Female; Glomerular Filtration Rate; Humans; Insulin-Like Growth Factor I; Inulin; | 1993 |
MR velocity mapping measurement of renal artery blood flow in patients with impaired kidney function.
Topics: Aged; Blood Flow Velocity; Chromium Radioisotopes; Edetic Acid; Electrocardiography; Female; Humans; | 1996 |
Early experience with extended use of insulin-like growth factor-1 in advanced chronic renal failure.
Topics: Adult; Aged; Blood Urea Nitrogen; Creatinine; Drug Tolerance; Female; Hemodynamics; Humans; Insulin- | 1997 |
Kidney function in cyclosporine-treated pediatric heart transplant recipients.
Topics: Adolescent; Azathioprine; Biopsy; Chelating Agents; Child; Child, Preschool; Chromium Radioisotopes; | 1997 |
Glomerular filtration rate measurement in cirrhotic patients with renal failure.
Topics: Creatinine; Female; Glomerular Filtration Rate; Humans; Inulin; Kidney Failure, Chronic; Liver Cirrh | 1998 |
Simultaneous determination of inulin and p-aminohippuric acid in plasma and urine by reversed-phase high-performance liquid chromatography.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Insulin; Kidney Failure, Chronic; Male; p-Amino | 2001 |
High-throughput multi-analyte screening for renal disease using capillary electrophoresis.
Topics: Creatine; Creatinine; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Kidney Failure | 2001 |
Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney.
Topics: Animals; Anions; Biological Transport; Dose-Response Relationship, Drug; Female; Furans; Indican; Ki | 2002 |
Acute effects of acetylsalicylic acid in patients with chronic renal insufficiency.
Topics: Aged; Aspirin; Diuresis; Drug Interactions; Female; Furosemide; Glomerular Filtration Rate; Humans; | 1977 |
Effect of fenoldopam in dogs with spontaneous renal insufficiency.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Administration, Oral; Animals; Creatinin | 1990 |
Renal tolerance for ioxaglate in patients with chronic renal failure.
Topics: Adult; Aged; Coronary Angiography; Glomerular Filtration Rate; Humans; Inulin; Ioxaglic Acid; Kidney | 1991 |
Converting enzyme inhibition in chronic renal failure.
Topics: Adult; Body Weight; Captopril; Creatinine; Female; Humans; Hypertension, Renal; Inulin; Kidney Failu | 1989 |
Differential effects of the degree of renal damage on p-aminohippuric acid and inulin clearances in rats.
Topics: Aminohippuric Acids; Animals; Dose-Response Relationship, Drug; Inulin; Kidney; Kidney Failure, Chro | 1989 |