Page last updated: 2024-10-22

p-aminohippuric acid and Diabetes Mellitus, Type 2

p-aminohippuric acid has been researched along with Diabetes Mellitus, Type 2 in 7 studies

p-Aminohippuric Acid: The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.
p-aminohippurate : A hippurate that is the conjugate base of p-aminohippuric acid, arising from deprotonation of the carboxy group.
p-aminohippuric acid : An N-acylglycine that is the 4-amino derivative of hippuric acid; used as a diagnostic agent in the measurement of renal plasma flow.

Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Research Excerpts

ExcerptRelevanceReference
"To examine whether glomerular hemodynamic parameters in humans are associated with glycemic control indices, by simultaneously measuring clearance of inulin (Cin) and para-aminohippuric acid (CPHA)."1.40Significant association of poor glycemic control with increased resistance in efferent arterioles--study of inulin and para-aminohippuric acid clearance in humans. ( Emoto, M; Fukumoto, S; Ichii, M; Inaba, M; Ishimura, E; Mori, K; Nakatani, S; Ohno, Y; Tsuda, A, 2014)
"GFR of the subjects with type 2 diabetes was next examined."1.28[Measurement of renal plasma flow and glomerular filtration rates in diabetic subjects]. ( Ebata, K; Haneda, M; Kikkawa, R; Shigeta, Y; Sugimoto, T, 1992)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ontawong, A1
Saowakon, N1
Vivithanaporn, P1
Pongchaidecha, A1
Lailerd, N1
Amornlerdpison, D1
Lungkaphin, A1
Srimaroeng, C1
Tsuda, A1
Ishimura, E1
Ohno, Y1
Ichii, M1
Nakatani, S1
Mori, K1
Fukumoto, S1
Emoto, M1
Inaba, M1
Ritt, M1
Ott, C1
Raff, U1
Schneider, MP1
Schuster, I1
Hilgers, KF1
Schlaich, MP1
Schmieder, RE1
Pruijm, M1
Wuerzner, G1
Maillard, M1
Bovet, P1
Renaud, C1
Bochud, M1
Burnier, M1
Baylis, C1
Atzpodien, EA1
Freshour, G1
Engels, K1
Stankovic, AR1
Fisher, ND1
Hollenberg, NK1
Haneda, M1
Kikkawa, R1
Ebata, K1
Sugimoto, T1
Shigeta, Y1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Linagliptin on Renal Endothelium Function in Patients With Type 2 Diabetes[NCT01835678]Phase 365 participants (Actual)Interventional2012-10-31Completed
Prospective Study on Endothelial Function in Subjects With Type 2 Diabetes Mellitus[NCT00905528]69 participants (Anticipated)Observational2002-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for p-aminohippuric acid and Diabetes Mellitus, Type 2

ArticleYear
Antioxidant and renoprotective effects of Spirogyra neglecta (Hassall) Kützing extract in experimental type 2 diabetic rats.
    BioMed research international, 2013, Volume: 2013

    Topics: Animals; Antioxidants; Biological Transport; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ

2013
Significant association of poor glycemic control with increased resistance in efferent arterioles--study of inulin and para-aminohippuric acid clearance in humans.
    Diabetes research and clinical practice, 2014, Volume: 104, Issue:2

    Topics: Adult; Aged; Arterioles; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; F

2014
Renal vascular endothelial function in hypertensive patients with type 2 diabetes mellitus.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood

2009
Renal vascular endothelial function in hypertensive patients with type 2 diabetes mellitus.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood

2009
Renal vascular endothelial function in hypertensive patients with type 2 diabetes mellitus.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood

2009
Renal vascular endothelial function in hypertensive patients with type 2 diabetes mellitus.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood

2009
Glomerular hyperfiltration and increased proximal sodium reabsorption in subjects with type 2 diabetes or impaired fasting glucose in a population of the African region.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:7

    Topics: Absorption; Adult; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephr

2010
Peroxisome proliferator-activated receptor [gamma] agonist provides superior renal protection versus angiotensin-converting enzyme inhibition in a rat model of type 2 diabetes with obesity.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Body Weight; Diabetes Complication

2003
Prorenin and angiotensin-dependent renal vasoconstriction in type 1 and type 2 diabetes.
    Journal of the American Society of Nephrology : JASN, 2006, Volume: 17, Issue:12

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diabetes Mellitus, Type 1;

2006
[Measurement of renal plasma flow and glomerular filtration rates in diabetic subjects].
    Rinsho byori. The Japanese journal of clinical pathology, 1992, Volume: 40, Issue:7

    Topics: Diabetes Mellitus, Type 2; Glomerular Filtration Rate; Humans; Inulin; p-Aminohippuric Acid; Renal C

1992