p-aminohippuric acid has been researched along with ADPKD in 3 studies
p-Aminohippuric Acid: The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.
p-aminohippurate : A hippurate that is the conjugate base of p-aminohippuric acid, arising from deprotonation of the carboxy group.
p-aminohippuric acid : An N-acylglycine that is the 4-amino derivative of hippuric acid; used as a diagnostic agent in the measurement of renal plasma flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with autosomal dominant polycystic kidney disease (ADPKD) (n = 4) and medullary sponge kidneys (MSK) (n = 3) with normal glomerular filtration rate (GFR), determined by inulin clearance, and effective renal plasma flow (ERPF), measured by p-aminohippurate clearance, underwent measurement of proximal and distal tubular functions." | 1.30 | Renal tubular dysfunction in patients with cystic disease of the kidneys. ( Freeman, RB; McKenna, BA; Pabico, RC, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Irazabal, MV | 1 |
| Torres, VE | 1 |
| Hogan, MC | 1 |
| Glockner, J | 1 |
| King, BF | 1 |
| Ofstie, TG | 1 |
| Krasa, HB | 1 |
| Ouyang, J | 1 |
| Czerwiec, FS | 1 |
| Tanner, GA | 1 |
| Gretz, N | 1 |
| Shao, Y | 1 |
| Evan, AP | 1 |
| Steinhausen, M | 1 |
| Pabico, RC | 1 |
| McKenna, BA | 1 |
| Freeman, RB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Longitudinal Efficacy and Safety Study of Tolvaptan on Autosomal Dominant Polycystic Kidney Disease Patients (LET-PKD Study)[NCT02729662] | 118 participants (Actual) | Interventional | 2016-10-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for p-aminohippuric acid and ADPKD
| Article | Year |
|---|---|
Short-term effects of tolvaptan on renal function and volume in patients with autosomal dominant polycystic kidney disease.
Topics: Adult; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Biomarkers; Contrast Media; Creatini | 2011 |
2 other studies available for p-aminohippuric acid and ADPKD
| Article | Year |
|---|---|
Organic anion secretion in polycystic kidney disease.
Topics: Animals; Anions; Disease Models, Animal; Female; Fluoresceins; Heterozygote; Humans; Ion Transport; | 1997 |
Renal tubular dysfunction in patients with cystic disease of the kidneys.
Topics: Adult; Female; Glomerular Filtration Rate; Glucose; Humans; Kidney Concentrating Ability; Kidney Tub | 1998 |