p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe and Weight-Loss

p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe has been researched along with Weight-Loss* in 1 studies

Other Studies

1 other study(ies) available for p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe and Weight-Loss

ArticleYear
Pyrazole Agonist of the Apelin Receptor Improves Symptoms of Metabolic Syndrome in Mice.
    Journal of medicinal chemistry, 2021, 03-25, Volume: 64, Issue:6

    Apelin receptor agonism improves symptoms of metabolic syndrome. However, endogenous apelin peptides have short half-lives, making their utility as potential drugs limited. Previously, we had identified a novel pyrazole-based agonist scaffold. Systematic modification of this scaffold was performed to produce compounds with improved ADME properties. Compound

    Topics: Animals; Apelin Receptors; Humans; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Pyrazoles; Weight Loss

2021