Page last updated: 2024-08-22

ozone and Metaplasia

ozone has been researched along with Metaplasia in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's11 (42.31)18.2507
2000's9 (34.62)29.6817
2010's4 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harkema, JR; Wagner, JG3
Buglak, N; Harkema, JR; Jackson-Humbles, DN; Kumagai, K; Lewandowski, RP; Li, N; Van Dyken, SJ; Wagner, JG; White, K1
Harkema, JR; Hotchkiss, LA; Jackson-Humbles, DN; Lewandowski, RP; Vetter, NA; Wagner, JG1
Ballinger, CA; Bartolucci, AA; Carey, SA; Harkema, JR; McDonald, RJ; Plopper, CG; Postlethwait, EM1
Tesfaigzi, Y1
Harkema, JR; Hotchkiss, JA; Van Dyken, SJ; Wagner, JG; Wierenga, JR1
Avila-Casado, MC; Avila-Costa, MR; Fortoul, TI; Gonzalez-Villalva, A; López, MC; Mussali-Galante, P; Ostrosky-Shejet, P; Rojas, E; Valverde, M1
Chang, LY; Crapo, JD; Mellick, PW; Ménache, MG; Mercer, RR; Stockstill, BL1
Chang, LY; Crapo, JD; Ménache, MG; Mercer, RR; Stockstill, BL1
Catalano, PJ; Griffith, WC; Gross, EA; Harkema, JR; Morgan, KT1
Harkema, JR; Hotchkiss, JA1
Griffith, WC; Harkema, JR; Hotchkiss, JA1
Cho, H; Harkema, JR; Hilaski, R; Hotchkiss, JA; Regan, K; Slack, K; Spencer, P1
Harkema, JR; Hotchkiss, JA; Tesfaigzi, J1
Fanucchi, MV; Harkema, JR; Hotchkiss, JA1
Barr, EB; Basbaum, C; Bennett, CB; Gallup, M; Harkema, JR; Hotchkiss, JA; Lee, JK1
Bennett, CB; Cho, HY; Harkema, JR; Hotchkiss, JA2
Cho, HY; Harkema, JR; Hotchkiss, JA1
Luster, MI1
Harkema, JR; Hotchkiss, JA; Van Dyken, SJ; Wagner, JG1
Harkema, JR; Hotchkiss, JA; Wagner, JG1
Penha, PD; Werthamer, S1
Carr, JJ; Schwarz, LH; Soskind, L; Werthamer, S1

Reviews

6 review(s) available for ozone and Metaplasia

ArticleYear
Innate Lymphoid Cell-Dependent Airway Epithelial and Inflammatory Responses to Inhaled Ozone: A New Paradigm in Pathogenesis.
    Toxicologic pathology, 2019, Volume: 47, Issue:8

    Topics: Air Pollutants; Animals; Humans; Immunity, Innate; Inhalation Exposure; Lymphocytes; Metaplasia; Ozone; Respiratory Mucosa; Respiratory Tract Diseases; Species Specificity

2019
Non-allergic models of mucous cell metaplasia and mucus hypersecretion in rat nasal and pulmonary airways.
    Novartis Foundation symposium, 2002, Volume: 248

    Topics: Animals; Drosophila Proteins; Endotoxins; Epithelial Cells; ErbB Receptors; Exocrine Glands; Exocytosis; Goblet Cells; Hyperplasia; Inflammation; Lung; Membrane Glycoproteins; Metaplasia; Mucins; Mucus; Nasal Mucosa; Neutrophils; Organ Specificity; Ozone; Rats; Rats, Inbred F344; Receptors, Cell Surface; Secretory Rate; Toll-Like Receptors

2002
The role of apoptotic regulators in metaplastic mucous cells.
    Novartis Foundation symposium, 2002, Volume: 248

    Topics: Allergens; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Bezafibrate; Cell Division; Endotoxins; Epithelial Cells; Exocrine Glands; Genes, bcl-2; Goblet Cells; Inflammation; Inflammation Mediators; Lipopolysaccharides; Metaplasia; Mucous Membrane; Ozone; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred BN; Smoke

2002
Epithelial and inflammatory responses in the airways of laboratory rats coexposed to ozone and biogenic substances: enhancement of toxicant-induced airway injury.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2005, Volume: 57 Suppl 1

    Topics: Air Pollutants; Animals; Biological Factors; Disease Models, Animal; Drug Synergism; Endotoxins; Inflammation; Inhalation Exposure; Metaplasia; Neutrophils; Ovalbumin; Ozone; Rats; Rats, Inbred F344; Respiratory Mucosa; Respiratory Tract Diseases

2005
Ozone- and endotoxin-induced mucous cell metaplasias in rat airway epithelium: novel animal models to study toxicant-induced epithelial transformation in airways.
    Toxicology letters, 1993, Volume: 68, Issue:1-2

    Topics: Animals; Disease Models, Animal; Endotoxins; Lung; Metaplasia; Mucous Membrane; Nasal Mucosa; Ozone; Rats; Respiratory System

1993
Ozone-induced mucous cell metaplasia.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 60, Issue:2

    Topics: Air Pollutants; Animals; Humans; Inhalation Exposure; Metaplasia; Oxidants, Photochemical; Ozone; Respiratory Mucosa

2001

Other Studies

20 other study(ies) available for ozone and Metaplasia

ArticleYear
Innate Lymphoid Cells Mediate Pulmonary Eosinophilic Inflammation, Airway Mucous Cell Metaplasia, and Type 2 Immunity in Mice Exposed to Ozone.
    Toxicologic pathology, 2017, Volume: 45, Issue:6

    Topics: Air Pollutants; Animals; DNA-Binding Proteins; Immunity, Innate; Immunity, Mucosal; Inhalation Exposure; Interleukin Receptor Common gamma Subunit; Lymphocytes; Male; Metaplasia; Mice, Inbred C57BL; Mice, Knockout; Ozone; Pulmonary Eosinophilia; Respiratory Mucosa

2017
Strain Differences in a Murine Model of Air Pollutant-induced Nonatopic Asthma and Rhinitis.
    Toxicologic pathology, 2017, Volume: 45, Issue:1

    Topics: Air Pollutants; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Gene Expression; Immunity, Mucosal; Male; Metaplasia; Mice, Inbred BALB C; Mice, Inbred C57BL; Ozone; Respiratory Mucosa; Rhinitis; Species Specificity

2017
Persistent rhinitis and epithelial remodeling induced by cyclic ozone exposure in the nasal airways of infant monkeys.
    American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 300, Issue:2

    Topics: Air Pollutants; Animals; Antioxidants; Child; Disease Models, Animal; Gene Expression; Glutamate-Cysteine Ligase; Glutathione; Humans; Macaca mulatta; Male; Metaplasia; Nasal Mucosa; Neutrophils; Ozone; Rhinitis; RNA, Messenger

2011
Ozone exposure enhances endotoxin-induced mucous cell metaplasia in rat pulmonary airways.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 74, Issue:2

    Topics: Administration, Intranasal; Animals; Bronchoalveolar Lavage Fluid; Drug Synergism; Inhalation Exposure; Lipopolysaccharides; Lung; Male; Metaplasia; Mucin 5AC; Mucins; Neutrophil Infiltration; Neutrophils; Oxidants, Photochemical; Ozone; Pseudomonas aeruginosa; Rats; Rats, Inbred F344; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2003
Genotoxic differences by sex in nasal epithelium and blood leukocytes in subjects residing in a highly polluted area.
    Environmental research, 2004, Volume: 94, Issue:3

    Topics: Adult; Air Pollutants; Analysis of Variance; Comet Assay; DNA Damage; Female; Histological Techniques; Humans; Leukocytes; Male; Metaplasia; Mexico; Nasal Mucosa; Ozone; Sex Factors; Urban Health

2004
Bronchiolarized metaplasia and interstitial fibrosis in rat lungs chronically exposed to high ambient levels of ozone.
    Toxicology and applied pharmacology, 1995, Volume: 134, Issue:2

    Topics: Animals; Bronchi; Female; Male; Metaplasia; Oxidants, Photochemical; Ozone; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Sex Factors

1995
Consequences of prolonged inhalation of ozone on F344/N rats: collaborative studies. Part VIII: Morphometric analysis of structural alterations in alveolar regions.
    Research report (Health Effects Institute), 1995, Issue:65 Pt 8-9

    Topics: Analysis of Variance; Animals; Bronchi; Dose-Response Relationship, Drug; Epithelium; Female; Lung Diseases, Interstitial; Macrophages, Alveolar; Male; Metaplasia; Ozone; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Sex Factors; Time Factors

1995
Consequences of prolonged inhalation of ozone on F344/N rats: collaborative studies. Part VII: Effects on the nasal mucociliary apparatus.
    Research report (Health Effects Institute), 1994, Issue:65 Pt 7

    Topics: Administration, Inhalation; Air Pollutants; Animals; Bone Resorption; Cilia; Cytoplasmic Granules; Dose-Response Relationship, Drug; Eosinophils; Epithelium; Female; Hyperplasia; Male; Metaplasia; Nasal Bone; Nasal Mucosa; Nasal Septum; Ozone; Rats; Rats, Inbred F344; Rhinitis

1994
Mucous cell metaplasia in rat nasal epithelium after a 20-month exposure to ozone: a morphometric study of epithelial differentiation.
    American journal of respiratory cell and molecular biology, 1997, Volume: 16, Issue:5

    Topics: Animals; Cell Differentiation; Epithelium; Female; Male; Metaplasia; Nasal Mucosa; Ozone; Rats; Rats, Inbred F344

1997
Fluticasone propionate attenuates ozone-induced rhinitis and mucous cell metaplasia in rat nasal airway epithelium.
    American journal of respiratory cell and molecular biology, 1998, Volume: 18, Issue:1

    Topics: Administration, Topical; Androstadienes; Animals; Anti-Inflammatory Agents; Cell Count; DNA; Epithelial Cells; Fluticasone; Glucocorticoids; Male; Metaplasia; Nasal Mucosa; Neutrophils; Ozone; Rats; Rats, Inbred F344; Rhinitis

1998
Expression of the Bcl-2 protein in nasal epithelia of F344/N rats during mucous cell metaplasia and remodeling.
    American journal of respiratory cell and molecular biology, 1998, Volume: 18, Issue:6

    Topics: Animals; Blotting, Western; Epithelium; Immunohistochemistry; Male; Metaplasia; Mucous Membrane; Nasal Mucosa; Ozone; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344; Respiratory System

1998
Endotoxin potentiates ozone-induced mucous cell metaplasia in rat nasal epithelium.
    Toxicology and applied pharmacology, 1998, Volume: 152, Issue:1

    Topics: Animals; Cell Count; DNA Primers; Drug Synergism; Epithelial Cells; Lipopolysaccharides; Male; Metaplasia; Mucin-5B; Mucins; Nasal Mucosa; Oxidants, Photochemical; Ozone; Pseudomonas aeruginosa; Rats; Rats, Inbred F344; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Turbinates

1998
Long-lasting effects of chronic ozone exposure on rat nasal epithelium.
    American journal of respiratory cell and molecular biology, 1999, Volume: 20, Issue:3

    Topics: Animals; Epithelium; Inhalation Exposure; Male; Metaplasia; Nasal Mucosa; Ozone; Rats; Rats, Inbred F344; Turbinates

1999
Effects of pre-existing rhinitis on ozone-induced mucous cell metaplasia in rat nasal epithelium.
    Toxicology and applied pharmacology, 1999, Jul-15, Volume: 158, Issue:2

    Topics: Animals; Endotoxins; Epithelial Cells; Inflammation; Male; Metaplasia; Mucins; Nasal Mucosa; Neutrophils; Ozone; Random Allocation; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rhinitis; RNA, Messenger; Time Factors

1999
Inflammatory and epithelial responses during the development of ozone-induced mucous cell metaplasia in the nasal epithelium of rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 51, Issue:1

    Topics: Administration, Inhalation; Animals; Bromodeoxyuridine; Cell Count; DNA; Goblet Cells; Male; Metaplasia; Mucin-5B; Mucins; Neutrophils; Oxidants, Photochemical; Ozone; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Rhinitis; RNA, Messenger; Turbinates; Up-Regulation

1999
Neutrophil-dependent and neutrophil-independent alterations in the nasal epithelium of ozone-exposed rats.
    American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:2 Pt 1

    Topics: Animals; DNA; Epithelial Cells; Leukocyte Count; Male; Metaplasia; Mucins; Nasal Mucosa; Neutrophil Infiltration; Neutrophils; Ozone; Rats; Rats, Inbred F344; RNA, Messenger; Up-Regulation

2000
Endotoxin enhancement of ozone-induced mucous cell metaplasia is neutrophil-dependent in rat nasal epithelium.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 60, Issue:2

    Topics: Air Pollutants; Animals; Drug Interactions; Immune Sera; Inhalation Exposure; Lipopolysaccharides; Male; Metaplasia; Mucins; Nasal Mucosa; Neutropenia; Neutrophil Infiltration; Neutrophils; Ozone; Pseudomonas aeruginosa; Rats; Rats, Inbred F344; RNA, Messenger; Turbinates

2001
Effects of ozone and endotoxin coexposure on rat airway epithelium: potentiation of toxicant-induced alterations.
    Environmental health perspectives, 2001, Volume: 109 Suppl 4

    Topics: Animals; Disease Models, Animal; Drug Interactions; Endotoxins; Epithelium; Lung; Male; Metaplasia; Neutrophils; Ozone; Pseudomonas aeruginosa; Rats; Rats, Inbred F344; Respiratory Mucosa; Respiratory System

2001
Pulmonary lesions induced by long-term exposure to ozone. II. Ultrastructure observations of proliferative and regressive lesions.
    Archives of environmental health, 1974, Volume: 29, Issue:5

    Topics: Animals; Bronchi; Epithelial Cells; Epithelium; Hyperplasia; Lung Diseases; Metaplasia; Mice; Microscopy, Electron; Ozone; Pulmonary Alveoli; Time Factors; Trachea

1974
Ozone-induced pulmonary lesions. Severe epithelial changes following sublethal doses.
    Archives of environmental health, 1970, Volume: 20, Issue:1

    Topics: Adenoma; Animals; Bronchial Diseases; Epithelium; Hyperplasia; Lung Diseases; Lung Neoplasms; Male; Metaplasia; Mice; Ozone; Pneumonia; Pulmonary Fibrosis

1970