ozone has been researched along with Bronchial Hyperreactivity in 138 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 63 (45.65) | 18.2507 |
| 2000's | 50 (36.23) | 29.6817 |
| 2010's | 24 (17.39) | 24.3611 |
| 2020's | 1 (0.72) | 2.80 |
| Authors | Studies |
|---|---|
| Adouli, J; Bennett, WC; Budney, SD; Chason, KD; Cruse, G; German, Z; Hedgespeth, BA; Hua, X; Jania, CM; Jaspers, I; Kelada, SN; Kong, X; Lazarowski, ER; Oby, BT; Randell, SH; Schworer, SA; Smith, GJ; Tilley, SL; van Heusden, C | 1 |
| Bao, A; Bao, W; Fei, X; Zhang, M; Zhang, X; Zhang, Y; Zhou, X | 1 |
| Bae, DJ; Jang, AS; Lee, MS; Moon, KY; Park, MK | 1 |
| Chang, YJ; Chuang, YT; Dekruyff, RH; Freeman, GJ; Hsu, JT; Kasahara, DI; Kim, HY; Lee, HH; Martin, T; Savage, PB; Shore, SA; Umetsu, DT | 1 |
| Chen, L; Deng, Z; Gao, ZC; Ge, HQ; Pu, XP; Sun, SY; Wu, DY; Zhang, LR; Zhou, JJ; Zhu, ZP | 1 |
| Adcock, I; Bhavsar, P; Chang, Y; Chung, KF; Clarke, C; Li, F; Seiffert, JM; Wiegman, C; Zhang, J; Zhou, X; Zhu, J | 1 |
| Adcock, I; Chang, Y; Chung, KF; Gong, J; Hong, Y; Li, F; Wiegman, CH; Zhang, JJ; Zhang, M; Zhang, P; Zhou, X | 1 |
| Ammit, AJ; Chung, KF; Clark, AR; Hussain, F; Li, F; Pinart, M; Shirali, S; Zhu, J | 1 |
| Adcock, IM; Bao, W; Barnes, PJ; Bittner, A; Chung, KF; Clarke, CJ; Haji, G; Kanerva, J; Kirkham, PA; Michaeloudes, C; Murphy, MP; Narang, P; Pavlidis, S; Rao, N; Russell, KE; Wiegman, CH | 1 |
| Cho, Y; Hunt, G; Kasahara, DI; Liao, JK; Mathews, JA; Park, CY; Shore, SA; Wurmbrand, AP | 1 |
| Lambert, JA; Song, W | 1 |
| Campen, MJ; Herbert, G; Lucas, SN; Sanchez, B; Zychowski, KE | 1 |
| Alexis, NE; Bennett, WD; Brar, SS; Bromberg, PA; Ivins, S; London, SJ; Travlos, G; Wu, J | 1 |
| Fryer, AD; Jacoby, DB; Wicher, SA | 1 |
| Fryer, AD; Jacoby, DB; Verhein, KC | 1 |
| Shore, SA; Williams, ES; Zhu, M | 1 |
| Adcock, IM; Chung, KF; Durham, A; Higgins, LS; Issa, R; Kapoun, A; Leung, SY; Medicherla, S; Williams, AS | 1 |
| Adcock, IM; Chung, KF; De Sanctis, GT; Eynott, PR; Jupp, R; Leung, SY; Nath, P; Resnick, R; Williams, AS | 1 |
| Fischer, BM; Foster, WM; Ghio, AJ; Grover, AR; Jaiswal, AK; Potts, EN; Voynow, JA; Zheng, S | 1 |
| Foster, WM; Garantziotis, S; Hollingsworth, JW; Kimata, K; Li, Z; Morgan, DL; Noble, PW; Potts, EN; Savani, RC; Schwartz, DA; Zhuo, L | 1 |
| Berhane, K; Gilliland, FD; Lee, YL; McConnell, R | 1 |
| Dekruyff, RH; Matangkasombut, P; Pichavant, M; Umetsu, DT | 1 |
| Auten, RL; Fischer, B; Foster, WM; Huang, Y; Mason, SN; Potts, EN | 1 |
| Blackwell, TS; Foster, WM; Garantziotis, S; Hollingsworth, JW; Li, Z; Lindsey, JY; Polosukhin, VV; Potts, EN; Schwartz, DA; Stober, VP | 1 |
| Gelfand, EW; Larsen, ST; Matsubara, S; McConville, G; Poulsen, SS | 1 |
| Blair, IA; Christmas, P; Cooper, PR; Douaidy, K; Mesaros, AC; Mittelman, MA; Panettieri, RA; Soberman, RJ; Stark, CM; Zhang, J | 1 |
| Gao, G; Howard, ST; Liu, C; Liu, HJ; Qin, XQ; Xiang, Y; Zhu, XL | 1 |
| Fryer, AD; Hazari, MS; Jacoby, DB; Jacoby, IW; Moulton, BC; Verhein, KC | 1 |
| Amatullah, H; Grasemann, H; Khanna, N; North, ML; Scott, JA; Silverman, F; Urch, B | 1 |
| Du, W; Eu, JP; Foster, WM; Frush, S; Garantziotis, S; He, YW; Hollingsworth, JW; Li, Z; Potts, EN | 1 |
| Foster, WM; Que, LG; Stiles, JV; Sundy, JS | 1 |
| Auten, RL; Foster, WM; Gilmour, MI; Krantz, QT; Mason, SN; Potts, EN | 1 |
| Chen, Q; Li, X; Shen, L; Xie, Z; Zhang, J | 1 |
| Feng, F; Foster, WM; Hollingsworth, JW; Li, Z; Potts-Kant, EN; Williams, KL; Wu, Y | 1 |
| Cohen, M; Gordon, T; Ménache, MG; Nadziejko, C; Regal, JF; Schlesinger, RB; Sisco, M; Zelikoff, JT | 1 |
| Barraclough-Mitchell, H; Bassett, DJ; DeLorme, MP; Elbon-Copp, C; Gao, X; Yang, H | 1 |
| Aizawa, H; Hara, N; Inoue, H; Yoshida, M | 1 |
| Allen, CB; Dakhama, A; Gelfand, EW; Giclas, PC; Holers, VM; Joetham, A; Kodama, T; Lambris, JD; McConville, G; Park, JW; Sfyroera, G; Shultz, LD; Takeda, K; Taube, C | 1 |
| Allen, CB; Balhorn, A; Dakhama, A; Dinarello, CA; Gelfand, EW; Joetham, A; Kim, SH; Kodama, T; Miyahara, N; Park, JW; Swasey, C; Takeda, K; Taube, C | 1 |
| Kelly, FJ; Mudway, IS | 1 |
| Fredberg, JJ; Johnston, RA; Rivera-Sanchez, YM; Schwartzman, IN; Shore, SA; Silverman, ES; Valone, J | 1 |
| Guan, CX; Luo, ZQ; Qin, XQ; Ren, YH; Sun, XH; Zhang, CQ | 2 |
| Balmes, JR; Chen, LL; Christian, DL; Ferrando, RE; Peden, DB; Tager, IB; Welch, BS | 1 |
| Flynt, L; Johnston, RA; Schwartzman, IN; Shore, SA | 1 |
| Fryer, AD; Gleich, GJ; Jacoby, DB; Yost, BL | 1 |
| Annesi-Maesano, I; Caillaud, D; Charpin, D; Kopferschmitt, C; Lavaud, F; Pénard-Morand, C; Raherison, C | 1 |
| Guan, C; Luo, Z; Qi, M; Qin, X; Wu, H; Xiang, Y; Zhang, C | 1 |
| Arakawa, H; Mochizuki, H; Morikawa, A; Muramatsu, R; Tokuyama, K | 1 |
| Johnston, RA; Shore, SA; Terry, RD; Theman, TA; Williams, ES | 1 |
| Lotriet, CJ; Oliver, DW; Venter, DP | 1 |
| Aubier, M; Bonay, M | 1 |
| Adcock, IM; Bennett, BL; Chung, KF; Ferguson, GD; Issa, R; Leung, SY; Nath, P; Williams, AS | 1 |
| Adcock, IM; Bhavsar, P; Chung, KF; Issa, R; Khorasani, NM; Leung, SY; Mitchell, JA; Nath, P; Williams, AS | 1 |
| Alexeeff, SE; Litonjua, AA; Schwartz, J; Sparrow, D; Suh, H; Vokonas, PS | 1 |
| Bric, JM; Gershwin, LJ; Joad, JP; Kott, KS; Peake, JL; Pinkerton, KE; Plopper, CG; Schelegle, ES | 1 |
| DeKruyff, RH; Goya, S; Iwakura, Y; Johnston, RA; Kim, HY; Matangkasombut, P; Meyer, EH; Pichavant, M; Savage, PB; Shore, SA; Umetsu, DT; Zhu, M | 1 |
| Amrani, Y; Haczku, A; Kierstein, S; Krytska, K; Panettieri, RA; Salmon, M; Sharma, S; Zangrilli, J | 1 |
| Johnston, RA; Lu, FL; Shore, SA; Terry, RD; Theman, TA; Williams, ES | 1 |
| Adcock, IM; Chung, KF; Khorasani, N; Leung, SY; McKenzie, AN; Nath, P; Williams, AS | 1 |
| Martin, JG | 1 |
| Conlon, PD; O'Byrne, PM; Stevens, WH | 1 |
| Lane, CG; O'Byrne, PM; Smith, W; Stevens, WH; Vanderheyden, C; Wattie, J | 1 |
| Fushimi, K; Ikezawa, K; Iwasaki, H; Kaminuma, O; Kikkawa, H; Matsubara, S; Shimazu, N | 1 |
| Chodimella, V; Lang, Z; Murlas, CG | 1 |
| Szarek, JL | 1 |
| Aizawa, H; Hara, N; Inoue, H; Koto, H; Takata, S | 2 |
| Elbon, CL; Fryer, AD; Gambone, LM | 1 |
| Covert, DS; Dumler, K; Hanley, QS; Koenig, JQ; McKinney, SE; Pierson, WE; Rebolledo, V | 1 |
| Cox, C; Frampton, MW; Gibb, FR; Levy, PC; Morrow, PE; Speers, DM; Utell, MJ | 1 |
| Fernandes, AL; McClean, PA; Molfino, NA; Raizenne, M; Silverman, F; Slutsky, AS; Tarlo, S; Zamel, N | 1 |
| Bassett, DJ; Fryer, AD; Schultheis, AH | 1 |
| Black, C; Ellis, R; Ford-Hutchinson, A; Lane, CG; O'Byrne, PM; Stevens, WH; Tagari, P; Woolley, MJ | 1 |
| Anderson, KR; Avol, EL; Hackney, JD; Linn, WS; Peng, RC; Shamoo, DA | 1 |
| Abdul-Salaam, S; Folinsbee, LJ; Harder, S; Horstman, DH; Ives, PJ; Kehrl, HR | 1 |
| Asano, M; Hiroi, J; Imai, T; Inamura, N; Inoue, H; Masunaga, T; Nakahara, K; Notsu, Y; Takishima, T; Yatabe, T | 1 |
| Broadley, KJ; Thorne, JR | 1 |
| Ichinose, M; Inoue, H; Katsumata, U; Kimura, K; Miura, M; Shirato, K; Takahashi, T; Takishima, T | 1 |
| Bric, JM; Hyde, DM; Joad, JP; McDonald, RJ; Pino, MV | 1 |
| Gebbers, JO | 1 |
| Garssen, J; Steerenberg, PA; van Bree, L; van Loveren, H | 1 |
| Beckett, WS; Chen, AH; Pace, PE; Perlman, GD; Sferlazza, SJ; Xu, XP | 1 |
| Chung, KF; Koto, H; Sun, J | 1 |
| Marthan, R; Roux, E; Savineau, JP | 1 |
| Chung, KF; Sun, J | 1 |
| Bast, A; van Bree, L; van Hoof, IH | 1 |
| Bast, A; Boere, AJ; Dormans, JA; Kramer, K; van Bree, L; van Hoof, HJ; Voss, HP | 1 |
| Canada, AT; Costa, DL; Fryer, AD; Schulman, SR; Winsett, DW | 1 |
| Chung, KF; Huang, TJ; Koto, H; Salmon, M; Zagorski, J | 1 |
| Lee, LY; Morton, RF; Wu, ZX | 1 |
| Aizawa, H; Hara, M; Hara, N; Inoue, H; Matsumoto, K; Shigyo, M; Takata, S | 1 |
| Cox, C; Frampton, MW; Looney, RJ; Morow, PE; Speers, DM; Torres, A; Tsai, Y; Utell, MJ; Voter, KZ; Whitin, JC | 1 |
| Aris, RM; Balmes, JR; Chen, LL; Christian, D; Ferrando, R; Finkbeiner, W; Hearne, PQ; Kelly, T; Scannell, C; Tager, IB; Welch, B | 1 |
| Cox, C; Frampton, MW; Morrow, PE; Speers, DM; Torres, A; Tsai, Y; Utell, MJ; Voter, KZ; Whitin, JC | 1 |
| Balmes, JR; Cox, C; Frampton, MW; Krein, PM; Speers, DM; Tsai, Y; Utell, MJ | 1 |
| Ikezawa, K; Kaminuma, O; Kikkawa, H; Matsubara, S | 1 |
| Aizawa, H; Hara, N; Inoue, H; Koto, H; Matsumoto, K; Nakano, H; Shigyo, M; Takata, S | 1 |
| Gustin, P; Montaño, LM; Romero, L; Sommer, B; Vargas, MH; Zamudio, P | 1 |
| Ameling, CB; Brunekreef, B; de Bruijne, CR; Fischer, PH; Hiemstra, PS; Hiltermann, TJ; Sterk, PJ; Stolk, J; van Bree, L; van der Zee, SC | 1 |
| Igarashi, A; Iijima, H; Shirato, K; Tamura, G | 1 |
| Brewer, JP; Drazen, JM; Galli, SJ; Martin, TR; Noviski, N; Skornik, WA | 1 |
| Arakawa, H; Mochizuki, H; Morikawa, A; Ohki, Y; Tokuyama, K | 1 |
| Hyvelin, JM; Marthan, R; Roux, E; Savineau, JP | 1 |
| Adcock, IM; Barnes, PJ; Chung, KF; Hisada, T; Huang, TJ; Nasuhara, Y; Salmon, M | 1 |
| Depuydt, P; Joos, GF; Pauwels, RA | 1 |
| Fryer, AD; Gleich, GJ; Yost, BL | 1 |
| Costa, DL; Devlin, RB; Dye, JA; Lehmann, JR; Madden, MC; Richards, JH | 1 |
| Bake, B; Hagberg, S; Henriksson, L; Ljungkvist, G; Olin, AC; Torén, K | 1 |
| Ball, B; Folinsbee, LJ; Horstman, D; Kehrl, HR; Peden, DB | 1 |
| Aizawa, H; Hara, N; Inoue, H; Koto, H; Matsumoto, K; Nakano, H | 1 |
| Aizawa, H; Hara, N; Inoue, H; Matsumoto, K; Nakano, H; Shigyo, M | 1 |
| Aizawa, H; Hara, N; Inoue, H; Kuwano, K; Matsumoto, K; Nadel, JA; Nakano, H | 1 |
| Dunster, C; Frischer, T; Grimminger, F; Holz, O; Jörres, RA; Kelly, FJ; Koschyk, S; Lubec, G; Magnussen, H; Müller, B; Niendorf, A; Seeger, W; Timm, P; Waschewski, M; Zachgo, W | 1 |
| Arakida, Y; Honda, K; Miyata, K; Morio, H; Ohga, K; Okada, Y; Suwa, K; Yamada, T; Yokota, M | 1 |
| Chung, KF; Hisada, T; Nasuhara, Y; Salmon, M | 1 |
| Herz, U; Neuhaus-Steinmetz, U; Renz, H; Uffhausen, F | 1 |
| Aizawa, H; Fukuyama, S; Hara, N; Inoue, H; Matsumoto, K; Nakano, H | 1 |
| Brown, RH; Foster, WM; Macri, K; Mitchell, CS | 1 |
| Cho, HY; Kleeberger, SR; Zhang, LY | 1 |
| Bergamaschi, E; Bernard, A; Broeckaert, F; De Palma, G; Mozzoni, P; Mutti, A; Vanni, S; Vettori, MV | 1 |
| Leikauf, GD; Santrock, J; Zhao, Q; Zhou, S | 1 |
| Doerschuk, CM; Le Blanc, B; Murthy, GG; Schwartzman, IN; Shore, SA | 1 |
| Lee, LY; Widdicombe, JG | 1 |
| Carbajal, V; Chavez, J; Montaño, LM; Segura, P; Sommer, B; Vargas, MH | 1 |
| Hiltermann, JT; Peters, EA; Stolk, J | 1 |
| Hots, TIu | 1 |
| Chism, D; Johnston, RA; Krishna Murthy, GG; Schwartzman, IN; Shore, SA | 1 |
| Darley-Usmar, V; O'Leary, VJ; Payne, AN; Wilkinson, D; Yeadon, M | 1 |
| Campos, MG; Montaño, LM; Ponce-Monter, H; Segura, P; Selman, M; Vanda, B; Vargas, MH | 1 |
| Bethel, RA; Tan, WC | 1 |
| Ikeda, H; Nishikawa, M; Nishiyama, H; Okubo, T; Suzuki, S; Yamakawa, H | 1 |
| Keller, R | 2 |
| Adachi, M; Hiyama, T; Idaira, K; Imai, T; Sugeta, A; Takahashi, T; Tanaka, Y | 1 |
| Adachi, M; Hiyama, T; Idaira, K; Imai, T; Suganuma, T; Sugeta, A; Takahashi, T; Tanaka, Y | 1 |
| Gontovnick, LS; Jones, GL; Lane, CG; Matsui, S; O'Byrne, PM; Woolley, MJ | 1 |
9 review(s) available for ozone and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Ozone-induced airway hyperresponsiveness: roles of ROCK isoforms.
Topics: Animals; Bronchial Hyperreactivity; Humans; Lung; Ozone; Protein Isoforms; Respiratory Hypersensitivity; rho-Associated Kinases | 2015 |
Natural killer T cells and the regulation of asthma.
Topics: Air Pollution; Allergens; Animals; Antigens; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Eosinophils; Haplorhini; Humans; Mice; Mice, Knockout; Models, Immunological; Natural Killer T-Cells; Ozone; Phenotype; Respiratory Tract Infections; Th2 Cells; Virus Diseases | 2009 |
An investigation of inhaled ozone dose and the magnitude of airway inflammation in healthy adults.
Topics: Administration, Inhalation; Adolescent; Adult; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cohort Studies; Female; Humans; Inflammation; Linear Models; Male; Neutrophils; Ozone; Probability; Risk Assessment | 2004 |
[Air pollution and allergic airway diseases].
Topics: Air Pollutants; Air Pollution; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Epithelial Cells; Humans; Immunoglobulin E; Macrophages; Mast Cells; Models, Immunological; Nitrogen Dioxide; Oxidative Stress; Ozone; Respiratory Hypersensitivity; Sulfur Dioxide; Vehicle Emissions | 2007 |
[Animal models of bronchial hyperreactivity].
Topics: Adenosine; Animals; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chronic Disease; Cytokines; Dextrans; Disease Models, Animal; Dogs; Guinea Pigs; Inflammation; Leukotrienes; Lipoxygenase; Mast Cells; Ozone; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Tachykinins | 1994 |
Health effects of outdoor air pollution. Committee of the Environmental and Occupational Health Assembly of the American Thoracic Society.
Topics: Adult; Aerosols; Air Pollutants; Air Pollution; Animals; Asthma; Biomarkers; Bronchial Hyperreactivity; Carbon Monoxide; Cardiovascular Diseases; Cattle; Cells, Cultured; Child; Emergencies; Environmental Health; Female; Hospitalization; Humans; Lead; Lung Diseases, Obstructive; Male; Models, Biological; Nitrogen Dioxide; Occupational Health; Ozone; Pregnancy; Rabbits; Rats; Respiratory Function Tests; Respiratory Tract Diseases; Sulfur Dioxide; United States | 1996 |
[Ozone: myths and reality].
Topics: Animals; Bronchial Hyperreactivity; Carcinogens; Humans; Mutagens; Oxidants, Photochemical; Ozone; Respiratory Hypersensitivity; Smog; Urban Health | 1996 |
Ozone alters T-helper cell mediated bronchial hyperreactivity and resistance to bacterial infection.
Topics: Administration, Inhalation; Animals; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Mice; Ozone; Picryl Chloride; T-Lymphocytes, Helper-Inducer; Th1 Cells; Th2 Cells | 1996 |
Modulation of airway sensitivity to inhaled irritants: role of inflammatory mediators.
Topics: Air Pollutants; Animals; Bronchial Hyperreactivity; Cats; Disease Models, Animal; Dogs; Humans; Irritants; Lung; Nerve Fibers; Ozone; Rats; Reflex; Tobacco Smoke Pollution | 2001 |
12 trial(s) available for ozone and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Effect of Obesity on Acute Ozone-Induced Changes in Airway Function, Reactivity, and Inflammation in Adult Females.
Topics: Adolescent; Adult; Biomarkers; Bronchial Hyperreactivity; Case-Control Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Inflammation; Obesity; Ozone; Respiratory System; Young Adult | 2016 |
Pulmonary function, bronchial reactivity, and epithelial permeability are response phenotypes to ozone and develop differentially in healthy humans.
Topics: Adolescent; Adult; Black or African American; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Cross-Over Studies; Female; Forced Expiratory Volume; Humans; Inhalation Exposure; Linear Models; Lung; Male; Methacholine Chloride; North Carolina; Ozone; Permeability; Phenotype; Radiopharmaceuticals; Respiratory Mucosa; Sex Factors; Technetium Tc 99m Pentetate; Time Factors; Vital Capacity; White People; Young Adult | 2011 |
Effect of ozone exposure on airway responses to inhaled allergen in asthmatic subjects.
Topics: Administration, Inhalation; Adolescent; Adult; Antigens, Dermatophagoides; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cross-Over Studies; Environmental Monitoring; Humans; Male; Organothiophosphorus Compounds; Ozone; Probability; Reference Values; Respiratory Function Tests; Sensitivity and Specificity; Statistics, Nonparametric | 2004 |
Oxidant and acid aerosol exposure in healthy subjects and subjects with asthma. Part I: Effects of oxidants, combined with sulfuric or nitric acid, on the pulmonary function of adolescents with asthma.
Topics: Acid Rain; Adolescent; Adult; Aerosols; Air Pollutants; Asthma; Bronchial Hyperreactivity; Bronchial Spasm; Child; Female; Follow-Up Studies; Humans; Hypersensitivity; Lung; Male; Nitric Acid; Nitrogen Dioxide; Oxidants; Ozone; Physical Exertion; Sulfuric Acids | 1994 |
Oxidant and acid aerosol exposure in healthy subjects and subjects with asthma. Part II: Effects of sequential sulfuric acid and ozone exposures on the pulmonary function of healthy subjects and subjects with asthma.
Topics: Adolescent; Adult; Aerosols; Air Pollutants; Asthma; Bronchial Hyperreactivity; Bronchial Spasm; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Lung; Male; Middle Aged; Oxidants; Ozone; Physical Exertion; Sulfuric Acids; Vital Capacity | 1994 |
The effect of pre-exposure to 0.12 ppm of ozone on exercise-induced asthma.
Topics: Adult; Asthma, Exercise-Induced; Atmosphere Exposure Chambers; Bronchial Hyperreactivity; Bronchoconstriction; Double-Blind Method; Exercise Test; Female; Forced Expiratory Volume; Humans; Male; Ozone | 1994 |
Effects of prolonged, repeated exposure to ozone, sulfuric acid, and their combination in healthy and asthmatic volunteers.
Topics: Adolescent; Adult; Air Pollutants; Airway Resistance; Asthma; Bronchial Hyperreactivity; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Ozone; Peak Expiratory Flow Rate; Respiratory Mechanics; Sulfuric Acids; Vital Capacity | 1994 |
Effects of ozone on normal and potentially sensitive human subjects. Part II: Airway inflammation and responsiveness to ozone in nonsmokers and smokers.
Topics: Adolescent; Adult; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Data Interpretation, Statistical; Double-Blind Method; Female; Flow Cytometry; Forced Expiratory Volume; Humans; Inflammation; Interleukin-6; Interleukin-8; Lung; Macrophages, Alveolar; Male; Mast Cells; Methacholine Chloride; Ozone; Physical Exertion; Reactive Oxygen Species; Respiratory Mechanics; Smoking; Spirometry; Therapeutic Irrigation; Time Factors; Vital Capacity | 1997 |
Increased specific airway reactivity of persons with mild allergic asthma after 7.6 hours of exposure to 0.16 ppm ozone.
Topics: Adult; Allergens; Animals; Antigens, Dermatophagoides; Asthma; Bronchial Hyperreactivity; Female; Glycoproteins; Histamine; Humans; Male; Mites; Ozone | 1999 |
Bronchial reactivity of healthy subjects: 18-20 h postexposure to ozone.
Topics: Adult; Air Pollutants; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Cross-Over Studies; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Oxidants, Photochemical; Ozone; Spirometry; Temperature; Time Factors | 2000 |
Polymorphism of quinone-metabolizing enzymes and susceptibility to ozone-induced acute effects.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Adult; Air Pollutants; Benzoquinones; Bronchial Hyperreactivity; Deoxyguanosine; Environmental Exposure; Female; Gene Frequency; Genotype; Glutathione Transferase; Haplotypes; Heterozygote; Homozygote; Humans; Male; NAD(P)H Dehydrogenase (Quinone); Oxidants, Photochemical; Ozone; Polymerase Chain Reaction; Proteins; Uteroglobin | 2001 |
Effect of apocynin on ozone-induced airway hyperresponsiveness to methacholine in asthmatics.
Topics: Acetophenones; Administration, Inhalation; Adult; Aerosols; Antioxidants; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; NADPH Oxidases; Ozone; Placebos | 2001 |
117 other study(ies) available for ozone and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Identification of an ATP/P2X7/mast cell pathway mediating ozone-induced bronchial hyperresponsiveness.
Topics: Adenosine Triphosphate; Animals; Bronchial Hyperreactivity; Female; Humans; Mast Cells; Mice; Ozone | 2021 |
Effects of ozone repeated short exposures on the airway/lung inflammation, airway hyperresponsiveness and mucus production in a mouse model of ovalbumin-induced asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Interleukin-13; Interleukin-1beta; Interleukin-4; Male; Mice; Mice, Inbred C57BL; Mucus; Ovalbumin; Oxidative Stress; Ozone; Pneumonia; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2018 |
The effects of pycnogenol on antioxidant enzymes in a mouse model of ozone exposure.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Disease Models, Animal; Female; Flavonoids; Inhalation Exposure; Lung; Malondialdehyde; Mice; Mice, Inbred BALB C; Nitric Oxide; Oxidative Stress; Ozone; Plant Extracts; Uric Acid; Vitamin A | 2013 |
T-cell immunoglobulin and mucin domain 1 deficiency eliminates airway hyperreactivity triggered by the recognition of airway cell death.
Topics: Animals; Apoptosis; Asthma; Bronchi; Bronchial Hyperreactivity; Epithelial Cells; Hepatitis A Virus Cellular Receptor 1; Membrane Proteins; Mice; Mice, Inbred BALB C; Natural Killer T-Cells; Ozone; Respiratory Syncytial Virus Infections | 2013 |
Treatment responses of procaterol and CD38 inhibitors in an ozone-induced airway hyperresponsiveness mice model.
Topics: ADP-ribosyl Cyclase 1; Animals; Anti-Asthmatic Agents; Benzoates; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Indoles; Leukocyte Count; Lung; Male; Membrane Glycoproteins; Methacholine Chloride; Mice; NF-kappa B; Ozone; Procaterol | 2013 |
Effects of N-acetylcysteine in ozone-induced chronic obstructive pulmonary disease model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Apoptosis; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Deoxyguanosine; Disease Models, Animal; Emphysema; Expectorants; Gene Expression; Lung; Malondialdehyde; Mice; Ozone; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests | 2013 |
Inhibitory effect of hydrogen sulfide on ozone-induced airway inflammation, oxidative stress, and bronchial hyperresponsiveness.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cytokines; Gasotransmitters; HSP27 Heat-Shock Proteins; Hydrogen Sulfide; Inflammation; Male; Malondialdehyde; Mice; Oxidants, Photochemical; Oxidative Stress; Ozone; p38 Mitogen-Activated Protein Kinases; RNA, Messenger | 2015 |
Role of mitogen-activated protein kinase phosphatase-1 in corticosteroid insensitivity of chronic oxidant lung injury.
Topics: Adrenal Cortex Hormones; Animals; Bronchial Hyperreactivity; Dexamethasone; Dual Specificity Phosphatase 1; Inflammation; Interleukin-13; Lung Injury; Male; Matrix Metalloproteinase 12; Mice; Mice, Inbred C57BL; Oxidants; Oxidative Stress; Ozone; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema | 2014 |
Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease.
Topics: Adult; Aged; Airway Remodeling; Animals; Antioxidants; Bronchial Hyperreactivity; Electron Transport Chain Complex Proteins; Female; Gene Expression Regulation; Humans; Hydrogen Peroxide; Male; Membrane Potential, Mitochondrial; Mice; Middle Aged; Mitochondria; Muscle, Smooth; Myocytes, Smooth Muscle; Organophosphorus Compounds; Oxidative Stress; Ozone; Pneumonia; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Respiratory System; Signal Transduction; Smoking; Ubiquinone | 2015 |
ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice.
Topics: Animals; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Interleukin-17; Mice; Mice, Mutant Strains; Muscle Contraction; Muscle, Smooth; Osteopontin; Oxidants, Photochemical; Ozone; Pneumonia; rho-Associated Kinases; Tumor Necrosis Factor-alpha | 2015 |
Hypoxia-induced pulmonary arterial hypertension augments lung injury and airway reactivity caused by ozone exposure.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Air Pollutants; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lung; Lung Injury; Male; Mice, Inbred C57BL; Organ Size; Ozone; Protein Kinase Inhibitors; rho-Associated Kinases; Ventricular Function, Right; Ventricular Pressure | 2016 |
Newly divided eosinophils limit ozone-induced airway hyperreactivity in nonsensitized guinea pigs.
Topics: Animals; Bradycardia; Bromodeoxyuridine; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell Division; Electric Stimulation; Eosinophils; Etanercept; Female; Guinea Pigs; Immunization; Lymphocytes; Macrophages; Methacholine Chloride; Monocytes; Neutrophils; Ozone; Vagus Nerve | 2017 |
IL-1 receptors mediate persistent, but not acute, airway hyperreactivity to ozone in guinea pigs.
Topics: Acetylcholine; Animals; Bone Marrow; Bradycardia; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Electric Stimulation; Eosinophil Major Basic Protein; Eosinophils; Female; Guinea Pigs; Hemodynamics; Inflammation; Injections, Intravenous; Interleukin-1beta; Models, Biological; Muscle Contraction; Muscle, Smooth; Neutrophils; Ozone; Receptors, Interleukin-1; Vagus Nerve | 2008 |
No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice.
Topics: Administration, Oral; Animals; Asthma; Blood Glucose; Body Weight; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Chemokines; Diabetes Mellitus; Disease Models, Animal; Female; Hypoglycemic Agents; Inflammation Mediators; Metformin; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Obese; Neutrophil Infiltration; Obesity; Ozone; Phenotype; Respiratory Mechanics | 2008 |
Role of p38 mitogen-activated protein kinase in ozone-induced airway hyperresponsiveness and inflammation.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation; Indoles; Inflammation; Lung; Male; Mice; Mice, Inbred BALB C; Neutrophils; Oxidants, Photochemical; Ozone; p38 Mitogen-Activated Protein Kinases; Time Factors | 2008 |
Role of cathepsin S in ozone-induced airway hyperresponsiveness and inflammation.
Topics: Air Pollutants; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Cathepsins; Drug Delivery Systems; Inflammation; Interferon-gamma; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Oxidative Stress; Ozone; Time Factors; Tumor Necrosis Factor-alpha | 2009 |
NAD(P)H quinone oxidoreductase 1 is essential for ozone-induced oxidative stress in mice and humans.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cells, Cultured; Chemokines; Dicumarol; Dinoprost; Enzyme Inhibitors; Epithelial Cells; Humans; Interleukin-8; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Oxidants; Oxidation-Reduction; Oxidative Stress; Ozone; Pneumonia; Time Factors | 2009 |
Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice.
Topics: Alpha-Globulins; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Hyaluronan Receptors; Hyaluronic Acid; Lung Injury; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Ozone; Peptides; Trachea | 2009 |
Ambient ozone modifies the effect of tumor necrosis factor G-308A on bronchitic symptoms among children with asthma.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Child; Environmental Exposure; Female; Genotype; Humans; Male; Ozone; Polymorphism, Genetic; Promoter Regions, Genetic; Surveys and Questionnaires; Tumor Necrosis Factor-alpha | 2009 |
Maternal exposure to particulate matter increases postnatal ozone-induced airway hyperreactivity in juvenile mice.
Topics: Air Pollutants; Air Pollution; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Inflammation; Inhalation Exposure; Lung; Maternal Exposure; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Oxidants, Photochemical; Ozone; Particulate Matter; Pregnancy; Prenatal Exposure Delayed Effects; Respiratory Function Tests | 2009 |
TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation.
Topics: Administration, Inhalation; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Hyaluronic Acid; Inflammation Mediators; Macrophages, Alveolar; Male; Mice; Mice, Inbred C57BL; Ozone; Pulmonary Alveoli; Toll-Like Receptor 4 | 2010 |
Ozone increases airway hyperreactivity and mucus hyperproduction in mice previously exposed to allergen.
Topics: Air Pollutants; Allergens; Animals; Asthma; Biomarkers; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Interactions; Inhalation Exposure; Leukocyte Count; Leukocytes; Lung; Methacholine Chloride; Mice; Mucus; Ovalbumin; Ozone; Periodic Acid-Schiff Reaction; Respiratory Function Tests | 2010 |
20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Hydroxyeicosatetraenoic Acids; Lipid Peroxidation; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Neutrophils; Ozone; Respiratory Hypersensitivity; Triazoles | 2010 |
Involvement of integrin beta4 in ozone stress-induced airway hyperresponsiveness.
Topics: Administration, Inhalation; Air Pollutants; Airway Resistance; Animals; Apoptosis; Bronchial Hyperreactivity; Cell Line; Gene Knockdown Techniques; Histamine; Humans; Integrin beta4; Lung; Male; Oxidative Stress; Ozone; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; RNA, Small Interfering | 2010 |
Three days after a single exposure to ozone, the mechanism of airway hyperreactivity is dependent on substance P and nerve growth factor.
Topics: Air Pollutants; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Female; Guinea Pigs; Humans; Lung; Male; Models, Biological; Nerve Growth Factor; Neurokinin-1 Receptor Antagonists; Ozone; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Time Factors; Vagus Nerve | 2011 |
Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways hyperresponsiveness in murine models of asthma.
Topics: Animals; Arginase; Asthma; Blotting, Western; Boronic Acids; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Disease Models, Animal; Enzyme Inhibitors; Female; Immunohistochemistry; Inflammation Mediators; Inhalation Exposure; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Oxidative Stress; Ozone; Particulate Matter; Up-Regulation | 2011 |
The role of the extracellular matrix protein mindin in airway response to environmental airways injury.
Topics: Animals; Bronchial Hyperreactivity; Extracellular Matrix Proteins; Immunity, Innate; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neutrophil Infiltration; Ozone; Toll-Like Receptor 4 | 2011 |
Maternal diesel inhalation increases airway hyperreactivity in ozone-exposed offspring.
Topics: Air Pollutants; Animals; Animals, Newborn; Bronchial Hyperreactivity; Cytokines; Female; Gestational Age; Inhalation Exposure; Lung; Maternal Exposure; Mice; Mice, Inbred C57BL; Ozone; Placenta; Pneumonia; Pregnancy; Pulmonary Alveoli; Ultrasonography; Vehicle Emissions | 2012 |
[Relevance of the expression of CTNNAL1 and the resistance of respiratory tract in rat with airway hyperresponsiveness].
Topics: Airway Resistance; alpha Catenin; Animals; Bronchial Hyperreactivity; Female; Inflammation; Male; Ozone; Rats; Rats, Wistar; RNA, Messenger | 2012 |
Hyaluronan activation of the Nlrp3 inflammasome contributes to the development of airway hyperresponsiveness.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carrier Proteins; Caspase 1; Hyaluronic Acid; Immunoblotting; Inflammasomes; Interleukin-1beta; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Ozone; Real-Time Polymerase Chain Reaction | 2012 |
Ozone-induced modulation of airway hyperresponsiveness in guinea pigs.
Topics: Acute Disease; Air Pollutants; Airway Resistance; Animals; Asthma; Body Weight; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Environmental Exposure; Female; Guinea Pigs; Male; Oxidants, Photochemical; Ozone; Respiratory Function Tests; Sex Characteristics; Time Factors | 2002 |
Hyperresponsive airways correlate with lung tissue inflammatory cell changes in ozone-exposed rats.
Topics: Administration, Inhalation; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cell Count; Collagenases; Inhalation Exposure; Lung; Male; Methacholine Chloride; Neutropenia; Neutrophils; Ozone; Rats; Rats, Wistar; Specific Pathogen-Free Organisms | 2002 |
Traditional oriental herbal medicine, Bakumondo-to, suppresses vagal neuro-effector transmission in guinea pig trachea.
Topics: Acetylcholine; Animals; Antitussive Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Drugs, Chinese Herbal; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Male; Medicine, East Asian Traditional; Muscle, Smooth; Neuroeffector Junction; Ozone; Prostaglandins; Synaptic Transmission; Trachea; Vagus Nerve; Vasodilator Agents | 2003 |
Complement activation is critical to airway hyperresponsiveness after acute ozone exposure.
Topics: Animals; Bronchial Hyperreactivity; Complement Activation; Complement Inactivator Proteins; Disease Models, Animal; Elapid Venoms; Female; Immunoglobulins; Mice; Mice, Inbred C57BL; Neutrophil Activation; Oxidants, Photochemical; Ozone; Receptors, Complement; Receptors, Complement 3b | 2004 |
Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytokines; Dexamethasone; Female; Gene Expression Profiling; Gene Expression Regulation; Glucocorticoids; Humans; Interleukin-1; Methacholine Chloride; Mice; Mice, Inbred C57BL; Neutrophils; Oxidants, Photochemical; Ozone; Receptors, Interleukin-1; Respiratory Mucosa | 2004 |
Differential effects of ozone on airway and tissue mechanics in obese mice.
Topics: Animals; Bronchial Hyperreactivity; Female; Lung; Male; Methacholine Chloride; Mice; Mice, Obese; Obesity; Ozone | 2004 |
Temporal and spatial distribution of VIP, CGRP and their receptors in the development of airway hyperresponsiveness in the lungs.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Epithelium; Lung; Ozone; Rabbits; Receptors, Calcitonin Gene-Related Peptide; Receptors, Vasoactive Intestinal Peptide; Vasoactive Intestinal Peptide | 2004 |
[The temporal and spatial distribution of vasoactive intestinal peptide and its receptor in the development of airway hyperresponsiveness].
Topics: Animals; Bronchial Hyperreactivity; Lung; Male; Ozone; Rabbits; Random Allocation; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Polypeptide, Type I; RNA, Messenger; Vasoactive Intestinal Peptide | 2004 |
Role of interleukin-6 in murine airway responses to ozone.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Drug Administration Schedule; Female; Interleukin-6; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Ozone; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; RNA, Messenger; Solubility | 2005 |
The changing role of eosinophils in long-term hyperreactivity following a single ozone exposure.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Electric Stimulation; Eosinophils; Female; Guinea Pigs; Lung; Neurons; Oxidants, Photochemical; Ozone; Receptor, Muscarinic M2; Specific Pathogen-Free Organisms; Vagus Nerve | 2005 |
Long-term exposure to background air pollution related to respiratory and allergic health in schoolchildren.
Topics: Air Pollutants; Air Pollution; Asthma; Bronchial Hyperreactivity; Child; Cross-Sectional Studies; Dermatitis, Atopic; Environmental Monitoring; Epidemiological Monitoring; Female; France; Humans; Hypersensitivity, Immediate; Male; Nitrogen Dioxide; Ozone; Prevalence; Rhinitis; Schools; Skin Tests; Sulfur Dioxide; Vehicle Emissions | 2005 |
Upregulation of substance P receptor expression by calcitonin gene-related peptide, a possible cooperative action of two neuropeptides involved in airway inflammation.
Topics: Animals; Asthma; Blotting, Western; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Guinea Pigs; Humans; Inflammation; Lung; Ozone; Protein-Tyrosine Kinases; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Substance P; Up-Regulation | 2007 |
Effect of inhaled histamine on airway epithelial cell swelling in ozone-exposed Guinea pigs.
Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Epithelial Cells; Guinea Pigs; Histamine; Histamine Agents; Ion Channels; Male; Oxidants, Photochemical; Ozone; Respiratory Mucosa | 2006 |
Pulmonary responses to acute ozone exposure in fasted mice: effect of leptin administration.
Topics: Airway Resistance; Animals; Body Mass Index; Bronchial Hyperreactivity; Corticosterone; Fasting; Leptin; Male; Mice; Mice, Inbred C57BL; Oxidants, Photochemical; Ozone; Pneumonia; Respiratory Mechanics | 2007 |
The pharmacological effects of ozone on isolated guinea pig tracheal preparations.
Topics: Animals; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Oxidants, Photochemical; Ozone; Trachea | 2007 |
Attenuation of ozone-induced airway inflammation and hyper-responsiveness by c-Jun NH2 terminal kinase inhibitor SP600125.
Topics: Animals; Anthracenes; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Gene Expression Regulation; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lung; Male; Mice; Mice, Inbred BALB C; Oligonucleotide Array Sequence Analysis; Ozone; Phosphorylation; Polymerase Chain Reaction; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun | 2007 |
Role of TLR2, TLR4, and MyD88 in murine ozone-induced airway hyperresponsiveness and neutrophilia.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression; Gene Expression Regulation; Gene Silencing; Interleukin-6; Male; Mice; Mice, Knockout; Myeloid Differentiation Factor 88; Neutrophil Infiltration; Neutrophils; Oxidative Stress; Ozone; Proteins; RNA, Messenger; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2007 |
Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA normative aging study.
Topics: Aged; Aging; Bronchial Hyperreactivity; Bronchial Provocation Tests; Environmental Exposure; Forced Expiratory Volume; Humans; Likelihood Functions; Male; Methacholine Chloride; Obesity; Ozone; Regression Analysis; Spirometry; United States; Veterans; Vital Capacity | 2007 |
The effects of inhaled corticosteroids on intrinsic responsiveness and histology of airways from infant monkeys exposed to house dust mite allergen and ozone.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Animals; Animals, Newborn; Antigens, Dermatophagoides; Bronchial Hyperreactivity; Bronchodilator Agents; Budesonide; Disease Models, Animal; Eosinophils; Leukocyte Count; Macaca mulatta; Mucins; Muscle, Smooth; Ozone; Respiratory Mucosa | 2008 |
Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17.
Topics: Air Pollutants; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Interleukin-13; Interleukin-17; Interleukin-4; Killer Cells, Natural; Leukocyte Count; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Ozone; T-Lymphocytes | 2008 |
Ozone inhalation induces exacerbation of eosinophilic airway inflammation and hyperresponsiveness in allergen-sensitized mice.
Topics: Administration, Inhalation; Allergens; Animals; Apoptosis; Aspergillus fumigatus; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Eosinophilia; Fas Ligand Protein; Female; Gene Expression Regulation; In Vitro Techniques; Inflammation; Mice; Mice, Inbred BALB C; Ovalbumin; Oxidants, Photochemical; Ozone; Trachea | 2008 |
Diet-induced obesity causes innate airway hyperresponsiveness to methacholine and enhances ozone-induced pulmonary inflammation.
Topics: Airway Resistance; Animals; Body Weight; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation Mediators; Injections, Intravenous; Lung Compliance; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Obesity; Ozone; Phenotype; Pneumonia; Pulmonary Edema; Respiratory Mechanics | 2008 |
Modulation of ozone-induced airway hyperresponsiveness and inflammation by interleukin-13.
Topics: Animals; Bronchial Hyperreactivity; Chemokine CCL20; Interleukin-13; Interleukin-4; Mice; Mice, Transgenic; Ozone | 2008 |
Ozone-induced oxygen radical release from bronchoalveolar lavage cells and airway hyper-responsiveness in dogs.
Topics: Acetylcholine; Administration, Inhalation; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dogs; Luminescent Measurements; Oxidants, Photochemical; Ozone; Reactive Oxygen Species | 1995 |
Effect of a leukotriene B4 receptor antagonist SC-53228 on ozone-induced airway hyperresponsiveness and inflammation in dogs.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Benzopyrans; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Dogs; Female; Luminescent Measurements; Male; Ozone; Random Allocation; Receptors, Leukotriene B4; Respiratory Burst | 1995 |
Importance of impairment of the airway epithelium for ozone-induced airway hyperresponsiveness in guinea pigs.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Dose-Response Relationship, Drug; Eosinophils; Epithelium; Guinea Pigs; Inflammation; Injections, Intravenous; Lung; Macrophages; Male; Methacholine Chloride; Neutrophils; Ozone; T-Lymphocytes; Trachea | 1995 |
Dexamethasone reduces tachykinin but not ACh airway hyperreactivity after O3.
Topics: Acetylcholine; Airway Resistance; Animals; Anti-Bacterial Agents; Bronchial Hyperreactivity; Capsaicin; Dexamethasone; Guinea Pigs; Male; Neprilysin; Oligopeptides; Ozone; Peptides; Substance P; Tachykinins | 1993 |
Consequences of prolonged inhalation of ozone on Fischer-344/N rats: collaborative studies. Part II: Mechanical properties, responses to bronchoactive stimuli, and eicosanoid release in isolated large and small airways.
Topics: Animals; Bronchial Hyperreactivity; Disease Models, Animal; Eicosanoids; Environmental Exposure; Female; Male; Ozone; Rats; Rats, Inbred F344; Respiratory Mechanics; Time Factors | 1994 |
An important role of tachykinins in ozone-induced airway hyperresponsiveness.
Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Capsaicin; Guinea Pigs; Histamine; Neutrophils; Ozone; Premedication; Tachykinins | 1995 |
Ozone exposure suppresses epithelium-dependent relaxation in feline airway.
Topics: Acetylcholine; Airway Resistance; Animals; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cats; Dose-Response Relationship, Drug; Epithelium; Female; Male; Nitric Oxide; Ozone | 1995 |
Ozone-induced loss of neuronal M2 muscarinic receptor function is prevented by cyclophosphamide.
Topics: Anesthesia; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Gallamine Triethiodide; Guinea Pigs; Leukocyte Count; Lung; Male; Muscarinic Antagonists; Neurons; Ozone; Pilocarpine; Pneumonia; Receptors, Muscarinic; Respiratory Mechanics | 1994 |
Ozone-induced airway hyperresponsiveness and loss of neuronal M2 muscarinic receptor function.
Topics: Acetylcholine; Animals; Blood Pressure; Bronchial Hyperreactivity; Electric Stimulation; Gallamine Triethiodide; Guanethidine; Guinea Pigs; Heart Rate; Male; Methacholine Compounds; Muscle, Smooth; Neurons; Ozone; Parasympathetic Nervous System; Pilocarpine; Receptors, Muscarinic; Sympathetic Nervous System; Vagus Nerve | 1994 |
Effect of FLAP antagonist MK-0591 on leukotriene production and ozone-induced airway responses in dogs.
Topics: 5-Lipoxygenase-Activating Proteins; Acetylcholine; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carrier Proteins; Dogs; Indoles; Inflammation; Leukotriene Antagonists; Leukotriene B4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Ozone; Quinolines; Respiratory System | 1994 |
Respiratory responses to repeated prolonged exposure to 0.12 ppm ozone.
Topics: Analysis of Variance; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cough; Environmental Exposure; Exercise Test; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride; Ozone; Pain; Plethysmography, Whole Body; Time Factors; Vital Capacity | 1994 |
A 5-lipoxygenase inhibitor, FR110302, inhibits ozone-induced airway hyperresponsiveness in guinea pigs and dogs.
Topics: Acetylcholine; Administration, Oral; Airway Resistance; Animals; Bronchial Hyperreactivity; Dogs; Guinea Pigs; Lipoxygenase Inhibitors; Naphthols; Ozone; Quinolines | 1993 |
Adenosine-induced bronchoconstriction in conscious hyperresponsive and sensitized guinea pigs.
Topics: Adenosine; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol; Guinea Pigs; Immunization; Male; Ovalbumin; Ozone; Platelet Activating Factor | 1994 |
Involvement of superoxide in ozone-induced airway hyperresponsiveness in anesthetized cats.
Topics: Acetylcholine; Anesthesia; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Catalase; Cats; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Free Radical Scavengers; Ozone; Polyethylene Glycols; Respiratory Mechanics; Superoxides; Time Factors | 1993 |
Effects of ozone and neutrophils on function and morphology of the isolated rat lung.
Topics: Animals; Bronchial Hyperreactivity; Humans; In Vitro Techniques; Lung; Methacholine Chloride; Neutrophils; Ozone; Perfusion; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Airway reactivity in welders: a controlled prospective cohort study.
Topics: Adult; Air Pollution; Analysis of Variance; Bronchial Hyperreactivity; Case-Control Studies; Cross-Over Studies; Female; Humans; Linear Models; Logistic Models; Male; Methacholine Chloride; Multivariate Analysis; Occupational Diseases; Ozone; Prospective Studies; Pulmonary Ventilation; Respiration Disorders; Smoking; Spirometry; Time Factors; United States; Welding | 1996 |
Interaction of ozone and allergen challenges on bronchial responsiveness and inflammation in sensitised guinea pigs.
Topics: Acetylcholine; Allergens; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Guinea Pigs; Immunization; Inflammation; Male; Ovalbumin; Oxidants, Photochemical; Ozone; Proteins | 1997 |
Human bronchial smooth muscle responsiveness after in vitro exposure to oxidizing pollutants.
Topics: Acrolein; Air Pollutants; Bronchi; Bronchial Hyperreactivity; Humans; In Vitro Techniques; Muscle, Smooth; Nitrogen Dioxide; Oxidation-Reduction; Ozone | 1996 |
Airway inflammation despite loss of bronchial hyper-responsiveness after multiple ozone exposures.
Topics: Adaptation, Physiological; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Guinea Pigs; Male; Neutrophils; Ozone | 1997 |
Changes in receptor function by oxidative stress in guinea pig tracheal smooth muscle.
Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Culture Techniques; Guinea Pigs; Hydrogen Peroxide; Hypochlorous Acid; Male; Oxidative Stress; Ozone; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1996 |
Changes in neuroreceptor function of tracheal smooth muscle following acute ozone exposure of guinea pigs.
Topics: Animals; Bronchial Hyperreactivity; Epithelium; Guinea Pigs; Isoproterenol; Male; Methacholine Chloride; Muscle, Smooth; Oxidants, Photochemical; Ozone; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1997 |
Airway hyperreactivity produced by short-term exposure to hyperoxia in neonatal guinea pigs.
Topics: Acetylcholine; Acetylcholinesterase; Airway Resistance; Animals; Animals, Newborn; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Electric Stimulation; Glutathione; Guinea Pigs; Humans; Hyperoxia; Incidence; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Ozone; Pilocarpine; Rats; Receptor, Muscarinic M2; Receptors, Muscarinic; Respiration; Vagus Nerve | 1997 |
Role of cytokine-induced neutrophil chemoattractant (CINC) in ozone-induced airway inflammation and hyperresponsiveness.
Topics: Acetylcholine; Animals; Antibodies; Bronchial Hyperreactivity; Chemokines; Chemokines, CXC; Chemotactic Factors; Growth Substances; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Neutrophils; Ozone; Rats; Rats, Inbred BN; RNA, Messenger | 1997 |
Role of tachykinins in ozone-induced airway hyperresponsiveness to cigarette smoke in guinea pigs.
Topics: Acetylcholine; Animals; Blood Pressure; Bronchi; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Ozone; Receptors, Neurokinin-2; Respiratory Mechanics; Substance P; Tachykinins; Tobacco Smoke Pollution | 1997 |
Effect of beta 2-agonists on histamine-induced airway microvascular leakage in ozone-exposed guinea pigs.
Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Animals; Blood-Air Barrier; Bronchial Hyperreactivity; Disease Models, Animal; Drug Evaluation, Preclinical; Ethanolamines; Extravascular Lung Water; Formoterol Fumarate; Guinea Pigs; Histamine; Male; Oxidants, Photochemical; Ozone | 1997 |
Airway inflammation in smokers and nonsmokers with varying responsiveness to ozone.
Topics: Adolescent; Adult; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Susceptibility; Female; Forced Expiratory Volume; Humans; Inflammation; Interleukin-6; Interleukin-8; Male; Neutrophils; Oxidants, Photochemical; Ozone; Smoking | 1997 |
Effects of ozone on normal and potentially sensitive human subjects. Part I: Airway inflammation and responsiveness to ozone in normal and asthmatic subjects.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Biopsy; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoscopy; Data Interpretation, Statistical; Female; Forced Expiratory Volume; Humans; Immunohistochemistry; Inflammation; Interleukin-8; Lung; Male; Methacholine Chloride; Middle Aged; Ozone; Physical Exertion; Therapeutic Irrigation; Time Factors; Vital Capacity | 1997 |
Effects of ozone on normal and potentially sensitive human subjects. Part III: Mediators of inflammation in bronchoalveolar lavage fluid from nonsmokers, smokers, and asthmatic subjects exposed to ozone: a collaborative study.
Topics: Adolescent; Adult; alpha-Macroglobulins; Asthma; Biopsy; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoscopy; Data Interpretation, Statistical; Female; Humans; Inflammation; Inflammation Mediators; Interleukin-6; Interleukin-8; Lung; Male; Ozone; Smoking; Time Factors | 1997 |
Angiotensin-converting enzyme inhibitors can potentiate ozone-induced airway hyperresponsiveness.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bronchial Hyperreactivity; Captopril; Drug Synergism; Enalapril; Guinea Pigs; Imidazoles; Imidazolidines; Male; Ozone; Respiratory Function Tests | 1997 |
The effects of a specific tachykinin receptor antagonist FK-224 on ozone-induced airway hyperresponsiveness and inflammation.
Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Guinea Pigs; Inflammation; Infusions, Intravenous; Male; Ozone; Peptides, Cyclic; Receptors, Tachykinin; Reference Values | 1997 |
Chronic exposure to ozone causes tolerance to airway hyperresponsiveness in guinea pigs: lack of SOD role.
Topics: Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Cell Count; Glycopeptides; Guinea Pigs; Inflammation; Infusions, Intravenous; Insufflation; Leukocytes; Lung; Macrophages; Male; Ozone; Substance P; Superoxide Dismutase | 1998 |
Asthma severity and susceptibility to air pollution.
Topics: Adult; Air Pollution; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodilator Agents; Female; Humans; Hypersensitivity, Immediate; Male; Netherlands; Oxidants, Photochemical; Ozone; Peak Expiratory Flow Rate; Prevalence; Prospective Studies; Respiratory Function Tests; Severity of Illness Index | 1998 |
Tazanolast inhibits ozone-induced airway hyperresponsiveness in guinea pigs.
Topics: Airway Resistance; Animals; Anti-Allergic Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Dose-Response Relationship, Drug; Guinea Pigs; Male; Mast Cells; Methacholine Chloride; Neutrophils; Ozone; Tetrazoles | 1998 |
Mast cell activation is not required for induction of airway hyperresponsiveness by ozone in mice.
Topics: Animals; Bronchial Hyperreactivity; Cell Degranulation; Leukocyte Count; Lung; Male; Mast Cells; Mice; Mice, Inbred Strains; Neutrophils; Oxidants, Photochemical; Ozone; Parasympathetic Nervous System; Respiratory Function Tests | 1999 |
Effect of ultrasonically nebulized distilled water on airway epithelial cell swelling in guinea pigs.
Topics: Administration, Inhalation; Airway Resistance; Algorithms; Animals; Bronchi; Bronchial Hyperreactivity; Cell Size; Epithelial Cells; Guinea Pigs; Male; Nebulizers and Vaporizers; Oxidants, Photochemical; Ozone; Ultrasonics; Water | 1999 |
Human isolated airway contraction: interaction between air pollutants and passive sensitization.
Topics: Acrolein; Adult; Air Pollutants; Airway Resistance; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; Female; Histamine; Humans; In Vitro Techniques; Male; Ozone; Respiratory Hypersensitivity | 1999 |
Inhibition of ozone-induced lung neutrophilia and nuclear factor-kappaB binding activity by vitamin A in rat.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; DNA-Binding Proteins; Lung; Male; Neutrophils; NF-kappa B; Oxidants, Photochemical; Ozone; Protein Binding; Rats; Rats, Inbred BN; Vasodilator Agents; Vitamin A | 1999 |
Ambient ozone concentrations induce airway hyperresponsiveness in some rat strains.
Topics: Alkaline Phosphatase; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Free Radical Scavengers; L-Lactate Dehydrogenase; Lung; Male; Oxidants, Photochemical; Ozone; Rats; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Lew; Rats, Long-Evans; Rats, Sprague-Dawley; Rats, Wistar; Serotonin; Species Specificity | 1999 |
Ozone-induced hyperresponsiveness and blockade of M2 muscarinic receptors by eosinophil major basic protein.
Topics: Animals; Antibodies; Blood Proteins; Bronchial Hyperreactivity; Bronchoconstriction; Electric Stimulation; Eosinophil Granule Proteins; Eosinophils; Female; Guinea Pigs; Interleukin-5; Muscarinic Agonists; Muscarinic Antagonists; Ozone; Pilocarpine; Ribonucleases; Vagus Nerve | 1999 |
Ozone effects on airway responsiveness, lung injury, and inflammation. Comparative rat strain and in vivo/in vitro investigations.
Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Culture Techniques; Epithelium; Inhalation Exposure; Lung Diseases; Male; Oxidants, Photochemical; Ozone; Pneumonia; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar; Respiratory Physiological Phenomena; Species Specificity; Trachea | 1999 |
Exhaled nitric oxide among pulpmill workers reporting gassing incidents involving ozone and chlorine dioxide.
Topics: Adult; Air Pollutants, Occupational; Biomarkers; Bronchial Hyperreactivity; Chlorine Compounds; Female; Humans; Industry; Lung; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Occupational Diseases; Occupational Exposure; Oxides; Ozone; Paper; Respiration; Respiratory Function Tests | 1999 |
Role of neutrophil elastase in ozone-induced airway responses in guinea-pigs.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Glycine; Guinea Pigs; Leukocyte Elastase; Male; Oxidants, Photochemical; Ozone; Serine Proteinase Inhibitors; Sulfonamides; Time Factors | 1999 |
Effect of the Chinese herbal medicine, Bakumondo-to, on airway hyperresponsiveness induced by ozone exposure in guinea-pigs.
Topics: Airway Resistance; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Membrane Permeability; Disease Models, Animal; Drugs, Chinese Herbal; Guinea Pigs; Lung; Male; Ozone; Random Allocation; Reference Values; Statistics, Nonparametric | 1999 |
Nitric oxide synthase inhibitors attenuate ozone-induced airway inflammation in guinea pigs. Possible role of interleukin-8.
Topics: Acetylcholine; Animals; Blotting, Northern; Bronchi; Bronchial Hyperreactivity; Bronchitis; Bronchoalveolar Lavage Fluid; Cells, Cultured; DNA Primers; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Guanidines; Guinea Pigs; Humans; In Situ Hybridization; Interleukin-8; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ozone; RNA, Messenger | 2000 |
The effect of repeated ozone exposures on inflammatory markers in bronchoalveolar lavage fluid and mucosal biopsies.
Topics: Adult; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Inflammation Mediators; Leukocyte Count; Male; Neutrophils; Ozone; Respiratory Mucosa | 2000 |
Effect of YM158, a dual lipid mediator antagonist, on immediate and late asthmatic responses, and on airway hyper-responsiveness in guinea pigs.
Topics: Acetylcholine; Airway Resistance; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Benzoquinones; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chromones; Dose-Response Relationship, Immunologic; Guinea Pigs; Heptanoic Acids; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Leukotriene Antagonists; Male; Membrane Proteins; Ovalbumin; Ozone; Receptors, Leukotriene; Receptors, Thromboxane; Tetrazoles; Thiazoles | 2000 |
Involvement of haemoxygenase-1 in ozone-induced airway inflammation and hyperresponsiveness.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchitis; Bronchoalveolar Lavage Fluid; Cell Count; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemoglobins; Lung; Male; Metalloporphyrins; Neutrophils; Ozone; Protoporphyrins; Rats; Rats, Inbred BN; Specific Pathogen-Free Organisms | 2000 |
Priming of allergic immune responses by repeated ozone exposure in mice.
Topics: Administration, Inhalation; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Dose-Response Relationship, Drug; Female; Hypersensitivity, Immediate; Immunoglobulin E; Immunoglobulin G; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ovalbumin; Oxidants, Photochemical; Ozone; Th2 Cells | 2000 |
Cyclooxygenase-2 participates in the late phase of airway hyperresponsiveness after ozone exposure in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Benzenesulfonates; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Guinea Pigs; Histamine; Immunohistochemistry; Isoenzymes; Male; Oxazoles; Oxidants, Photochemical; Ozone; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane A2 | 2000 |
Ozone-induced lung inflammation and hyperreactivity are mediated via tumor necrosis factor-alpha receptors.
Topics: Animals; Antigens, CD; Bronchial Hyperreactivity; Lung; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Ozone; Pneumonia; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; RNA, Messenger | 2001 |
Activation of eicosanoid metabolism in human airway epithelial cells by ozonolysis products of membrane fatty acids.
Topics: Air Pollutants; Aldehydes; Asthma; Bronchial Hyperreactivity; Cells, Cultured; Chromatography, High Pressure Liquid; Eicosanoids; Environmental Exposure; Fatty Acids; Humans; Hydrogen Peroxide; Hydrolysis; Lipid Peroxides; Maximum Allowable Concentration; Membrane Lipids; Oxidation-Reduction; Ozone; Radioimmunoassay; Respiratory Mucosa | 1995 |
Tumor necrosis factor receptor 2 contributes to ozone-induced airway hyperresponsiveness in mice.
Topics: Administration, Inhalation; Animals; Animals, Wild; Antigens, CD; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Environmental Exposure; Leukocyte Count; Methacholine Chloride; Mice; Mice, Knockout; Neutrophils; Oxidants, Photochemical; Ozone; Plethysmography, Whole Body; Pulmonary Ventilation; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Time Factors | 2001 |
Differences between inhaled and intravenous bronchial challenge to detect O(3)-induced hyperresponsiveness.
Topics: Acetylcholinesterase; Administration, Inhalation; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Guinea Pigs; Injections, Intravenous; Lung; Male; Motor Activity; Ozone; Respiration, Artificial; Respiratory Function Tests | 2001 |
[The effects of ozone and toxic air particles on airway function in mice].
Topics: Air Pollutants; Animals; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Male; Methacholine Compounds; Mice; Mice, Inbred BALB C; Ozone; Particle Size; Respiratory Function Tests; Titanium | 2001 |
Ozone-induced airway hyperresponsiveness is reduced in immature mice.
Topics: Administration, Inhalation; Aging; Animals; Animals, Newborn; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Female; Male; Methacholine Chloride; Mice; Mice, Inbred Strains; Oxidants, Photochemical; Ozone; Respiration | 2002 |
Mechanisms contributing to ozone-induced bronchial hyperreactivity in guinea-pigs.
Topics: Adenine Nucleotides; Animals; Ascorbic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Fentanyl; Glutathione; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase Inhibitors; Male; Neprilysin; Oligopeptides; Oxidation-Reduction; Ozone; Pyrilamine; Substance P; Vagus Nerve | 1992 |
O3-induced airway hyperresponsiveness to noncholinergic system and other stimuli.
Topics: Animals; Autonomic Nervous System; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Ovalbumin; Ozone; Substance P; Trachea; Vagus Nerve | 1992 |
The effect of platelet activating factor antagonist on ozone-induced airway inflammation and bronchial hyperresponsiveness in guinea pigs.
Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Eosinophils; Furans; Guinea Pigs; Male; Methacholine Chloride; Ozone; Platelet Activating Factor; Respiratory Function Tests | 1992 |
Combined effects of ozone and cigarette smoke on airway responsiveness and vascular permeability in guinea pigs.
Topics: Airway Resistance; Animals; Bronchi; Bronchial Hyperreactivity; Capillary Permeability; Dose-Response Relationship, Drug; Female; Guinea Pigs; Ozone; Tobacco Smoke Pollution; Trachea | 1992 |
[Asthma and ozone].
Topics: Air Pollutants; Asthma; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Humans; Oxidants, Photochemical; Ozone | 1992 |
[Role of thromboxane A2 and prostaglandin I2 in the increase of airway responsiveness in dogs after ozone exposure].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Atmosphere Exposure Chambers; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dogs; Epoprostenol; Female; Ozone; Thromboxane A2; Thromboxane B2 | 1992 |
[Inhibitory effect of S-1452, a specific thromboxane A2 receptor antagonist on the increase of airway responsiveness in dogs after ozone exposure].
Topics: Animals; Bridged Bicyclo Compounds; Bronchial Hyperreactivity; Dogs; Environmental Exposure; Fatty Acids, Monounsaturated; Female; Ozone; Receptors, Prostaglandin; Receptors, Thromboxane | 1992 |
[Effects of tropospheric ozone on human respiratory organs].
Topics: Air Pollutants; Asthma; Bronchial Hyperreactivity; Humans; Ozone; Respiratory System; Respiratory Tract Diseases | 1992 |
The effect of antioxidants on ozone-induced airway hyperresponsiveness in dogs.
Topics: Acetylcholine; Allopurinol; Animals; Antioxidants; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Deferoxamine; Dogs; Free Radicals; Ozone; Premedication | 1991 |