oxytocin and Bernard-Soulier-Syndrome

Bernard-Soulier Syndrome is a rare hereditary thrombocytopathy that manifests clinically by excessive bleeding out of proportion to the degree of thrombocytopenia. Only eight reports of Bernard-Soulier Syndrome in pregnancy have been previously described. In some patients the pregnancy course was smooth while in others post-partum haemorrhage was the most common complication. We present a primiparous female who had immediate and delayed post-partum haemorrhage that was managed conservatively. Review of the literature is also included.

Topics: Adult; Bernard-Soulier Syndrome; Consanguinity; Crystalloid Solutions; Dinoprost; Female; Humans; Isotonic Solutions; Oxytocin; Plasma Substitutes; Postpartum Hemorrhage; Pregnancy; Pregnancy Complications, Hematologic