oxytetracycline--anhydrous and Uterine-Cervicitis

In an urban clinic for sexually-transmitted diseases, 270 women with cervical swabs culture positive for Chlamydia trachomatis were treated with 250 mg oxytetracycline orally four times daily for 7 days. Chlamydial infection was found again in 17 of 220 (7.3%) women examined one month after treatment, and in 12 of 113 (9.7%) women reexamined three months after treatment. Even in cases where reinfection seemed unlikely, only 177 of 198 (89%) were cured. Most post-treatment infections were not clinically apparent, and laboratory follow-up was essential for evaluation of chemotherapy.

Topics: Chlamydia Infections; Chlamydia trachomatis; Drug Administration Schedule; Female; Humans; Oxytetracycline; Recurrence; Uterine Cervicitis

Chlamydia trachomatis was isolated from the cervix in 20.4 per cent (104/511) of women attending a department of genito-urinary medicine. Isolation rates ranged from 43.3 per cent in women with gonorrhoea to 4.2 per cent in women with no STD and who required no treatment. There was no association between the presence of chlamydia in the cervix and any symptom complex. Although high isolation rates were also noted in women with signs of cervicitis and in women whose partners had non-gonococcal urethritis, the accuracy of such clinical and epidemiological criteria in predicting cervical infection was low. In the absence of a screening service the chlamydial infection of 81 women (those who were not NGU contacts) would have been undiagnosed and untreated. The need for a screening service is discussed.

Topics: Adolescent; Adult; Chlamydia Infections; Chlamydia trachomatis; Female; Gonorrhea; Humans; Mass Screening; Neisseria gonorrhoeae; Oxytetracycline; Scotland; Uterine Cervical Diseases; Uterine Cervicitis

Topics: Adult; Candida albicans; Cervix Uteri; Contraceptive Devices; Family Practice; Female; Humans; London; Male; Methods; Microscopy; Neisseria gonorrhoeae; Oxytetracycline; Rectum; Trichomonas vaginalis; Urethra; Urethritis; Urine; Uterine Cervicitis; Vagina

Topics: Anti-Bacterial Agents; Female; Humans; Hydrocortisone; Intraabdominal Infections; Oxytetracycline; Trichomonas; Trichomonas Infections; Trichomonas Vaginitis; Uterine Cervicitis; Vaginitis